Year |
Citation |
Score |
2014 |
Al-Mawsawi LQ, Wu NC, Olson CA, Shi VC, Qi H, Zheng X, Wu TT, Sun R. High-throughput profiling of point mutations across the HIV-1 genome. Retrovirology. 11: 124. PMID 25522661 DOI: 10.1186/s12977-014-0124-6 |
0.391 |
|
2014 |
Al-Mawsawi LQ, Wu NC, De La Cruz J, Shi VC, Wu TT, Daar ES, Lewis MJ, Yang OO, Sun R. Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing. Aids Research and Human Retroviruses. 30: 806-11. PMID 24914638 DOI: 10.1089/Aid.2014.0097 |
0.341 |
|
2014 |
Qi H, Olson CA, Wu NC, Ke R, Loverdo C, Chu V, Truong S, Remenyi R, Chen Z, Du Y, Su SY, Al-Mawsawi LQ, Wu TT, Chen SH, Lin CY, et al. A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity. Plos Pathogens. 10: e1004064. PMID 24722365 DOI: 10.1371/Journal.Ppat.1004064 |
0.327 |
|
2012 |
Serrao E, Thys W, Demeulemeester J, Al-Mawsawi LQ, Christ F, Debyser Z, Neamati N. A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication. Plos One. 7: e45177. PMID 23028829 DOI: 10.1371/Journal.Pone.0045177 |
0.752 |
|
2011 |
Al-Mawsawi LQ, Neamati N. Allosteric inhibitor development targeting HIV-1 integrase. Chemmedchem. 6: 228-41. PMID 21275045 DOI: 10.1002/Cmdc.201000443 |
0.74 |
|
2011 |
Al-Mawsawi LQ, Neamati N. New Paradigm for Integrase Inhibition: Blocking Enzyme Function without Directly Targeting the Active Site Hiv-1 Integrase: Mechanism and Inhibitor Design. 457-476. DOI: 10.1002/9781118015377.ch29 |
0.494 |
|
2010 |
Debnath B, Al-Mawsawi LQ, Neamati N. Are we living in the end of the blockbuster drug era? Drug News & Perspectives. 23: 670-84. PMID 21180653 DOI: 10.1358/Dnp.2010.23.10.1506088 |
0.515 |
|
2008 |
Al-Mawsawi LQ, Al-Safi RI, Neamati N. Anti-infectives: clinical progress of HIV-1 integrase inhibitors. Expert Opinion On Emerging Drugs. 13: 213-25. PMID 18537517 DOI: 10.1517/14728214.13.2.213 |
0.694 |
|
2008 |
Al-Mawsawi LQ, Hombrouck A, Dayam R, Debyser Z, Neamati N. Four-tiered π interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity Virology. 377: 355-363. PMID 18514248 DOI: 10.1016/J.Virol.2008.04.030 |
0.633 |
|
2008 |
Al-Mawsawi LQ, Christ F, Dayam R, Debyser Z, Neamati N. Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase-DNA complex formation and catalysis Febs Letters. 582: 1425-1430. PMID 18331842 DOI: 10.1016/J.Febslet.2008.02.076 |
0.511 |
|
2008 |
Dayam R, Al-Mawsawi LQ, Zawahir Z, Witvrouw M, Debyser Z, Neamati N. Quinolone 3-carboxylic acid pharmacophore: Design of second generation HIV-1 integrase inhibitors Journal of Medicinal Chemistry. 51: 1136-1144. PMID 18281931 DOI: 10.1021/Jm070609B |
0.677 |
|
2008 |
Dayam R, Gundla R, Al-Mawsawi LQ, Neamati N. HIV-1 integrase inhibitors: 2005-2006 update. Medicinal Research Reviews. 28: 118-54. PMID 17979144 DOI: 10.1002/Med.20116 |
0.738 |
|
2007 |
Al-Mawsawi LQ, Dayam R, Taheri L, Witvrouw M, Debyser Z, Neamati N. Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors Bioorganic and Medicinal Chemistry Letters. 17: 6472-6475. PMID 17950601 DOI: 10.1016/J.Bmcl.2007.09.102 |
0.701 |
|
2007 |
Dayam R, Al-Mawsawi LQ, Neamati N. Substituted 2-pyrrolinone inhibitors of HIV-1 integrase. Bioorganic & Medicinal Chemistry Letters. 17: 6155-9. PMID 17911021 DOI: 10.1016/J.Bmcl.2007.09.061 |
0.682 |
|
2007 |
Al-Mawsawi LQ, Neamati N. Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy. Trends in Pharmacological Sciences. 28: 526-35. PMID 17888520 DOI: 10.1016/J.Tips.2007.09.005 |
0.67 |
|
2007 |
Deng J, Sanchez T, Al-Mawsawi LQ, Dayam R, Yunes RA, Garofalo A, Bolger MB, Neamati N. Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore. Bioorganic & Medicinal Chemistry. 15: 4985-5002. PMID 17502148 DOI: 10.1016/J.Bmc.2007.04.041 |
0.717 |
|
2007 |
Dayam R, Al-Mawsawi LQ, Neamati N. HIV-1 integrase inhibitors: an emerging clinical reality. Drugs in R&D. 8: 155-68. PMID 17472411 DOI: 10.2165/00126839-200708030-00003 |
0.696 |
|
2007 |
Al-Mawsawi LQ, Sechi M, Neamati N. Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity. Febs Letters. 581: 1151-6. PMID 17328897 DOI: 10.1016/J.Febslet.2007.02.023 |
0.672 |
|
2007 |
Deng J, Dayam R, Al-Mawsawi LQ, Neamati N. Design of second generation HIV-1 integrase inhibitors. Current Pharmaceutical Design. 13: 129-41. PMID 17269923 DOI: 10.2174/138161207779313687 |
0.694 |
|
2007 |
Dayam R, Grande F, Al-Mawsawi LQ, Neamati N. Recent advances in the design and discovery of small-molecule therapeutics targeting HER2/neu Expert Opinion On Therapeutic Patents. 17: 83-102. DOI: 10.1517/13543776.17.1.83 |
0.568 |
|
2006 |
Sechi M, Bacchi A, Carcelli M, Compari C, Duce E, Fisicaro E, Rogolino D, Gates P, Derudas M, Al-Mawsawi LQ, Neamati N. From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes. Journal of Medicinal Chemistry. 49: 4248-60. PMID 16821784 DOI: 10.1021/Jm060193M |
0.583 |
|
2006 |
Al-Mawsawi LQ, Fikkert V, Dayam R, Witvrouw M, Burke TR, Borchers CH, Neamati N. Discovery of a small-molecule HIV-1 integrase inhibitor-binding site. Proceedings of the National Academy of Sciences of the United States of America. 103: 10080-5. PMID 16785440 DOI: 10.1073/Pnas.0511254103 |
0.628 |
|
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