Gene S. Tan, Ph.D. - Publications

Affiliations: 
2007 Thomas Jefferson University 
Area:
Virology Biology, Microbiology Biology, Molecular Biology

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 He W, Tan GS, Mullarkey CE, Lee AJ, Lam MM, Krammer F, Henry C, Wilson PC, Ashkar AA, Palese P, Miller MS. Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus. Proceedings of the National Academy of Sciences of the United States of America. PMID 27698132 DOI: 10.1073/pnas.1609316113  0.6
2016 Leon PE, He W, Mullarkey CE, Bailey MJ, Miller MS, Krammer F, Palese P, Tan GS. Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647907 DOI: 10.1073/pnas.1613225113  0.6
2016 Henry Dunand CJ, Leon PE, Huang M, Choi A, Chromikova V, Ho IY, Tan GS, Cruz J, Hirsh A, Zheng NY, Mullarkey CE, Ennis FA, Terajima M, Treanor JJ, Topham DJ, et al. Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection. Cell Host & Microbe. 19: 800-813. PMID 27281570 DOI: 10.1016/j.chom.2016.05.014  0.6
2016 Tan GS, Leon PE, Albrecht RA, Margine I, Hirsh A, Bahl J, Krammer F. Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection. Plos Pathogens. 12: e1005578. PMID 27081859 DOI: 10.1371/journal.ppat.1005578  0.6
2016 Tran EE, Podolsky KA, Bartesaghi A, Kuybeda O, Grandinetti G, Wohlbold TJ, Tan GS, Nachbagauer R, Palese P, Krammer F, Subramaniam S. Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate. Mbio. 7. PMID 27006464 DOI: 10.1128/mBio.00257-16  0.6
2016 Chen CJ, Ermler ME, Tan GS, Krammer F, Palese P, Hai R. Influenza A viruses expressing intra- or inter-group chimeric hemagglutinins. Journal of Virology. PMID 26764009 DOI: 10.1128/JVI.03060-15  0.6
2016 Wohlbold TJ, Chromikova V, Tan GS, Meade P, Amanat F, Comella P, Hirsh A, Krammer F. Hemagglutinin stalk- and neuraminidase-specific monoclonal antibodies protect against lethal H10N8 influenza virus infection in mice Journal of Virology. 90: 851-861. DOI: 10.1128/JVI.02275-15  0.6
2015 Wang TT, Maamary J, Tan GS, Bournazos S, Davis CW, Krammer F, Schlesinger SJ, Palese P, Ahmed R, Ravetch JV. Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy. Cell. 162: 160-9. PMID 26140596 DOI: 10.1016/j.cell.2015.06.026  0.6
2014 Tan GS, Lee PS, Hoffman RM, Mazel-Sanchez B, Krammer F, Leon PE, Ward AB, Wilson IA, Palese P. Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin. Journal of Virology. 88: 13580-92. PMID 25210195 DOI: 10.1128/JVI.02289-14  0.6
2014 Krammer F, Albrecht RA, Tan GS, Margine I, Hai R, Schmolke M, Runstadler J, Andrews SF, Wilson PC, Cox RJ, Treanor JJ, García-Sastre A, Palese P. Divergent H7 immunogens offer protection from H7N9 virus challenge. Journal of Virology. 88: 3976-85. PMID 24453375 DOI: 10.1128/JVI.03095-13  0.6
2014 DiLillo DJ, Tan GS, Palese P, Ravetch JV. Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo. Nature Medicine. 20: 143-51. PMID 24412922 DOI: 10.1038/nm.3443  0.6
2013 Heaton NS, Leyva-Grado VH, Tan GS, Eggink D, Hai R, Palese P. In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. Journal of Virology. 87: 8272-81. PMID 23698304 DOI: 10.1128/JVI.00969-13  0.6
2012 Krammer F, Margine I, Tan GS, Pica N, Krause JC, Palese P. A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates. Plos One. 7: e43603. PMID 22928001 DOI: 10.1371/journal.pone.0043603  0.6
2012 Schneemann A, Speir JA, Tan GS, Khayat R, Ekiert DC, Matsuoka Y, Wilson IA. A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin. Journal of Virology. 86: 11686-97. PMID 22896619 DOI: 10.1128/JVI.01694-12  0.6
2012 Krammer F, Pica N, Hai R, Tan GS, Palese P. Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice. Journal of Virology. 86: 10302-7. PMID 22787225 DOI: 10.1128/JVI.01336-12  0.6
2012 Tan GS, Krammer F, Eggink D, Kongchanagul A, Moran TM, Palese P. A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. Journal of Virology. 86: 6179-88. PMID 22491456 DOI: 10.1128/JVI.00469-12  0.6
2012 Hai R, Krammer F, Tan GS, Pica N, Eggink D, Maamary J, Margine I, Albrecht RA, Palese P. Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes. Journal of Virology. 86: 5774-81. PMID 22398287 DOI: 10.1128/JVI.00137-12  0.6
2012 Pica N, Hai R, Krammer F, Wang TT, Maamary J, Eggink D, Tan GS, Krause JC, Moran T, Stein CR, Banach D, Wrammert J, Belshe RB, García-Sastre A, Palese P. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses. Proceedings of the National Academy of Sciences of the United States of America. 109: 2573-8. PMID 22308500 DOI: 10.1073/pnas.1200039109  0.6
2010 Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P. Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 18979-84. PMID 20956293 DOI: 10.1073/pnas.1013387107  0.6
2010 Wang TT, Tan GS, Hai R, Pica N, Petersen E, Moran TM, Palese P. Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins. Plos Pathogens. 6: e1000796. PMID 20195520 DOI: 10.1371/journal.ppat.1000796  0.6
2010 Préhaud C, Wolff N, Terrien E, Lafage M, Mégret F, Babault N, Cordier F, Tan GS, Maitrepierre E, Ménager P, Chopy D, Hoos S, England P, Delepierre M, Schnell MJ, et al. Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein. Science Signaling. 3: ra5. PMID 20086240 DOI: 10.1126/scisignal.2000510  0.6
2009 Cenna J, Hunter M, Tan GS, Papaneri AB, Ribka EP, Schnell MJ, Marx PA, McGettigan JP. Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates. The Journal of Infectious Diseases. 200: 1251-60. PMID 19764884 DOI: 10.1086/605949  0.6
2009 Preuss MA, Faber ML, Tan GS, Bette M, Dietzschold B, Weihe E, Schnell MJ. Intravenous inoculation of a bat-associated rabies virus causes lethal encephalopathy in mice through invasion of the brain via neurosecretory hypothalamic fibers. Plos Pathogens. 5: e1000485. PMID 19543379 DOI: 10.1371/journal.ppat.1000485  0.6
2008 Cenna J, Tan GS, Papaneri AB, Dietzschold B, Schnell MJ, McGettigan JP. Immune modulating effect by a phosphoprotein-deleted rabies virus vaccine vector expressing two copies of the rabies virus glycoprotein gene. Vaccine. 26: 6405-14. PMID 18804506 DOI: 10.1016/j.vaccine.2008.08.069  0.6
2008 Wirblich C, Tan GS, Papaneri A, Godlewski PJ, Orenstein JM, Harty RN, Schnell MJ. PPEY motif within the rabies virus (RV) matrix protein is essential for efficient virion release and RV pathogenicity. Journal of Virology. 82: 9730-8. PMID 18667490 DOI: 10.1128/JVI.00889-08  0.6
2007 Tan GS, Preuss MA, Williams JC, Schnell MJ. The dynein light chain 8 binding motif of rabies virus phosphoprotein promotes efficient viral transcription. Proceedings of the National Academy of Sciences of the United States of America. 104: 7229-34. PMID 17438267 DOI: 10.1073/pnas.0701397104  0.6
2005 Schnell MJ, Tan GS, Dietzschold B. The application of reverse genetics technology in the study of rabies virus (RV) pathogenesis and for the development of novel RV vaccines. Journal of Neurovirology. 11: 76-81. PMID 15804964 DOI: 10.1080/13550280590900436  0.6
2005 Tan GS, McKenna PM, Koser ML, McLinden R, Kim JH, McGettigan JP, Schnell MJ. Strong cellular and humoral anti-HIV Env immune responses induced by a heterologous rhabdoviral prime-boost approach. Virology. 331: 82-93. PMID 15582655 DOI: 10.1016/j.virol.2004.10.018  0.6
2004 Koser ML, McGettigan JP, Tan GS, Smith ME, Koprowski H, Dietzschold B, Schnell MJ. Rabies virus nucleoprotein as a carrier for foreign antigens Proceedings of the National Academy of Sciences of the United States of America. 101: 9405-9410. PMID 15197258 DOI: 10.1073/pnas.0403060101  0.6
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