| Year |
Citation |
Score |
| 2000 |
Messer WS, Rajeswaran WG, Cao Y, Zhang HJ, el-Assadi AA, Dockery C, Liske J, O'Brien J, Williams FE, Huang XP, Wroblewski ME, Nagy PI, Peseckis SM. Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors. Pharmaceutica Acta Helvetiae. 74: 135-40. PMID 10812950 DOI: 10.1016/S0031-6865(99)00026-6 |
0.508 |
|
| 1999 |
Krishnan V, Pham WN, Messer WS, Peseckis SM. First fatty acylated dipeptides to affect muscarinic receptor ligand binding. Bioorganic & Medicinal Chemistry Letters. 9: 3363-8. PMID 10612600 DOI: 10.1016/S0960-894X(99)00604-6 |
0.426 |
|
| 1999 |
Huang XP, Williams FE, Peseckis SM, Messer WS. Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M1 muscarinic acetylcholine receptors Molecular Pharmacology. 56: 775-783. PMID 10496961 |
0.488 |
|
| 1999 |
Huang XP, Nagy PI, Williams FE, Peseckis SM, Messer WS. Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1 muscarinic receptors British Journal of Pharmacology. 126: 735-745. PMID 10188986 DOI: 10.1038/Sj.Bjp.0702301 |
0.553 |
|
| 1999 |
Messer W, Huang X, Nagy P, Williams F, Peseckis S. Mutant M1 muscarinic receptors with increased agonist affinity and G protein coupling Life Sciences. 64: 563. DOI: 10.1016/S0024-3205(99)90482-4 |
0.505 |
|
| 1999 |
Huang X, Williams F, Peseckis S, Messer W. Mutant M1 muscarinic receptors with enhanced agonist activity Life Sciences. 64: 563. DOI: 10.1016/S0024-3205(99)90481-2 |
0.522 |
|
| 1998 |
Huang XP, Williams FE, Peseckis SM, Messer W.S. J. Pharmacological characterization of human m1 muscarinic acetylcholine receptors with double mutations at the junction of TM VI and the third extracellular domain Journal of Pharmacology and Experimental Therapeutics. 286: 1129-1139. PMID 9732369 |
0.515 |
|
| 1997 |
Huang X, Edgar M, Freed J, Peseckis S, Nagy P, Ojo B, Zhang H, Messer W. Molecular studies of agonist interactions with wild-type, T234A, and N507A m3 receptors Life Sciences. 60: 1178. DOI: 10.1016/S0024-3205(97)84329-9 |
0.464 |
|
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