Jeff B. Helms, Ph.D. - Publications

Affiliations: 
2010 Illinois State University, Normal, IL, United States 
Area:
Molecular Biology, Pharmacology, General Biophysics

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Tuohetahuntila M, Molenaar MR, Spee B, Brouwers JF, Houweling M, Vaandrager AB, Helms JB. ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells. Journal of Lipid Research. PMID 27179362 DOI: 10.1194/jlr.M066415  0.56
2016 Maric-Biresev J, Hunn JP, Krut O, Helms JB, Martens S, Howard JC. Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection. Bmc Biology. 14: 33. PMID 27098192 DOI: 10.1186/S12915-016-0255-4  0.56
2016 van Gestel RA, Brouwers JF, Ultee A, Helms JB, Gadella BM. Ultrastructure and lipid composition of detergent-resistant membranes derived from mammalian sperm and two types of epithelial cells. Cell and Tissue Research. 363: 129-45. PMID 26378009 DOI: 10.1007/s00441-015-2272-y  0.56
2015 Arroyo-Olarte RD, Brouwers JF, Kuchipudi A, Helms JB, Biswas A, Dunay IR, Lucius R, Gupta N. Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence. Plos Biology. 13: e1002288. PMID 26565995 DOI: 10.1371/journal.pbio.1002288  0.56
2015 Helms JB, Kaloyanova DV, Strating JR, van Hellemond JJ, van der Schaar HM, Tielens AG, van Kuppeveld FJ, Brouwers JF. Targeting of the hydrophobic metabolome by pathogens. Traffic (Copenhagen, Denmark). 16: 439-60. PMID 25754025 DOI: 10.1111/tra.12280  0.56
2015 Brachet A, Norwood S, Brouwers JF, Palomer E, Helms JB, Dotti CG, Esteban JA. LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic delivery. The Journal of Cell Biology. 208: 791-806. PMID 25753037 DOI: 10.1085/Jgp.1454Oia11  0.56
2015 Tuohetahuntila M, Spee B, Kruitwagen HS, Wubbolts R, Brouwers JF, van de Lest CH, Molenaar MR, Houweling M, Helms JB, Vaandrager AB. Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells. Biochimica Et Biophysica Acta. 1851: 220-30. PMID 25500141 DOI: 10.1016/j.bbalip.2014.12.003  0.56
2015 Lolicato F, Brouwers JF, de Lest CH, Wubbolts R, Aardema H, Priore P, Roelen BA, Helms JB, Gadella BM. The cumulus cell layer protects the bovine maturing oocyte against fatty acid-induced lipotoxicity. Biology of Reproduction. 92: 16. PMID 25297544 DOI: 10.1095/biolreprod.114.120634  0.56
2014 Boerke A, van der Lit J, Lolicato F, Stout TA, Helms JB, Gadella BM. Removal of GPI-anchored membrane proteins causes clustering of lipid microdomains in the apical head area of porcine sperm. Theriogenology. 81: 613-24. PMID 24377861 DOI: 10.1016/j.theriogenology.2013.11.014  0.56
2013 Galva C, Virgin GK, Helms JB, Gatto C. ATP protects against FITC labeling of Solanum lycopersicon and Arabidopsis thaliana Ca2+-ATPase ATP binding domains. Plant Physiology and Biochemistry : Ppb / SociéTé FrançAise De Physiologie VéGéTale. 71: 261-7. PMID 23974359 DOI: 10.1016/J.Plaphy.2013.07.010  0.56
2013 Aardema H, Lolicato F, van de Lest CH, Brouwers JF, Vaandrager AB, van Tol HT, Roelen BA, Vos PL, Helms JB, Gadella BM. Bovine cumulus cells protect maturing oocytes from increased fatty acid levels by massive intracellular lipid storage. Biology of Reproduction. 88: 164. PMID 23616596 DOI: 10.1095/biolreprod.112.106062  0.56
2013 Brouwers JF, Aalberts M, Jansen JW, van Niel G, Wauben MH, Stout TA, Helms JB, Stoorvogel W. Distinct lipid compositions of two types of human prostasomes. Proteomics. 13: 1660-6. PMID 23404715 DOI: 10.1002/pmic.201200348  0.56
2013 Boerke A, Brouwers JF, Olkkonen VM, van de Lest CH, Sostaric E, Schoevers EJ, Helms JB, Gadella BM. Involvement of bicarbonate-induced radical signaling in oxysterol formation and sterol depletion of capacitating mammalian sperm during in vitro fertilization. Biology of Reproduction. 88: 21. PMID 23115269 DOI: 10.1095/biolreprod.112.101253  0.56
2012 Cebollero E, van der Vaart A, Zhao M, Rieter E, Klionsky DJ, Helms JB, Reggiori F. Phosphatidylinositol-3-phosphate clearance plays a key role in autophagosome completion. Current Biology : Cb. 22: 1545-53. PMID 22771041 DOI: 10.1016/J.Cub.2012.06.029  0.56
2012 van Galen J, Olrichs NK, Schouten A, Serrano RL, Nolte-'t Hoen EN, Eerland R, Kaloyanova D, Gros P, Helms JB. Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization. Biochimica Et Biophysica Acta. 1818: 2175-83. PMID 22560898 DOI: 10.1016/J.Bbamem.2012.04.016  0.56
2012 Sodero AO, Vriens J, Ghosh D, Stegner D, Brachet A, Pallotto M, Sassoè-Pognetto M, Brouwers JF, Helms JB, Nieswandt B, Voets T, Dotti CG. Cholesterol loss during glutamate-mediated excitotoxicity. The Embo Journal. 31: 1764-73. PMID 22343944 DOI: 10.1038/Emboj.2012.31  0.56
2011 Vogels MW, van Balkom BW, Heck AJ, de Haan CA, Rottier PJ, Batenburg JJ, Kaloyanova DV, Helms JB. Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle. Proteomics. 11: 4477-91. PMID 21919203 DOI: 10.1002/Pmic.201100224  0.56
2011 Brouwers JF, Boerke A, Silva PF, Garcia-Gil N, van Gestel RA, Helms JB, van de Lest CH, Gadella BM. Mass spectrometric detection of cholesterol oxidation in bovine sperm. Biology of Reproduction. 85: 128-36. PMID 21415139 DOI: 10.1095/biolreprod.111.091207  0.56
2011 Vogels MW, van Balkom BW, Kaloyanova DV, Batenburg JJ, Heck AJ, Helms JB, Rottier PJ, de Haan CA. Identification of host factors involved in coronavirus replication by quantitative proteomics analysis. Proteomics. 11: 64-80. PMID 21182195 DOI: 10.1002/pmic.201000309  0.56
2010 Bot M, Bot I, Lopez-Vales R, van de Lest CH, Saulnier-Blache JS, Helms JB, David S, van Berkel TJ, Biessen EA. Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation. The American Journal of Pathology. 176: 3073-84. PMID 20431029 DOI: 10.2353/ajpath.2010.090009  0.56
2010 Van Galen J, Van Balkom BW, Serrano RL, Kaloyanova D, Eerland R, Stüven E, Helms JB. Binding of GAPR-1 to negatively charged phospholipid membranes: unusual binding characteristics to phosphatidylinositol. Molecular Membrane Biology. 27: 81-91. PMID 20095951 DOI: 10.3109/09687680903507080  0.56
2010 van der Meer-Janssen YP, van Galen J, Batenburg JJ, Helms JB. Lipids in host-pathogen interactions: pathogens exploit the complexity of the host cell lipidome. Progress in Lipid Research. 49: 1-26. PMID 19638285 DOI: 10.1016/j.plipres.2009.07.003  0.56
2009 Verheijen MH, Camargo N, Verdier V, Nadra K, de Preux Charles AS, Médard JJ, Luoma A, Crowther M, Inouye H, Shimano H, Chen S, Brouwers JF, Helms JB, Feltri ML, Wrabetz L, et al. SCAP is required for timely and proper myelin membrane synthesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 21383-8. PMID 19948958 DOI: 10.1073/Pnas.0905633106  0.56
2009 van de Wetering K, Feddema W, Helms JB, Brouwers JF, Borst P. Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo. Gastroenterology. 137: 1725-35. PMID 19577570 DOI: 10.1053/J.Gastro.2009.06.052  0.56
2009 Testerink N, van der Sanden MH, Houweling M, Helms JB, Vaandrager AB. Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex. Journal of Lipid Research. 50: 2182-92. PMID 19458387 DOI: 10.1194/jlr.M800660-JLR200  0.56
2007 Bleijerveld OB, Brouwers JF, Vaandrager AB, Helms JB, Houweling M. The CDP-ethanolamine pathway and phosphatidylserine decarboxylation generate different phosphatidylethanolamine molecular species. The Journal of Biological Chemistry. 282: 28362-72. PMID 17673461 DOI: 10.1074/jbc.M703786200  0.56
2007 Huitema LF, van Weeren PR, van Balkom BW, Visser T, van de Lest CH, Barneveld A, Helms JB, Vaandrager AB. Soluble factors released by ATDC5 cells affect the formation of calcium phosphate crystals. Biochimica Et Biophysica Acta. 1774: 1108-17. PMID 17669701 DOI: 10.1016/j.bbapap.2007.06.005  0.56
2007 Li X, Kaloyanova D, van Eijk M, Eerland R, van der Goot G, Oorschot V, Klumperman J, Lottspeich F, Starkuviene V, Wieland FT, Helms JB. Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure. Molecular Biology of the Cell. 18: 1261-71. PMID 17251550 DOI: 10.1091/mbc.E06-03-0236  0.56
2006 Gatto C, Helms JB, Prasse MC, Huang SY, Zou X, Arnett KL, Milanick MA. Similarities and differences between organic cation inhibition of the Na,K-ATPase and PMCA. Biochemistry. 45: 13331-45. PMID 17073454 DOI: 10.1021/Bi060667J  0.56
2006 Huitema LF, van Weeren PR, Barneveld A, van de Lest CH, Helms JB, Vaandrager AB. Iron ions derived from the nitric oxide donor sodium nitroprusside inhibit mineralization. European Journal of Pharmacology. 542: 48-53. PMID 16828741 DOI: 10.1016/j.ejphar.2006.06.006  0.56
2006 Huitema LF, Vaandrager AB, van Weeren PR, Barneveld A, Helms JB, van de Lest CH. The nitric oxide donor sodium nitroprusside inhibits mineralization in ATDC5 cells. Calcified Tissue International. 78: 171-7. PMID 16523220 DOI: 10.1007/s00223-005-1233-y  0.56
2005 van Gestel RA, Brewis IA, Ashton PR, Helms JB, Brouwers JF, Gadella BM. Capacitation-dependent concentration of lipid rafts in the apical ridge head area of porcine sperm cells. Molecular Human Reproduction. 11: 583-90. PMID 16051681 DOI: 10.1093/molehr/gah200  0.56
2005 van Gestel RA, Helms JB, Brouwers JF, Gadella BM. Effects of methyl-beta-cyclodextrin-mediated cholesterol depletion in porcine sperm compared to somatic cells. Molecular Reproduction and Development. 72: 386-95. PMID 16044473 DOI: 10.1002/mrd.20351  0.56
2005 Kokubo H, Kayed R, Glabe CG, Saido TC, Iwata N, Helms JB, Yamaguchi H. Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain. Brain Research. 1045: 224-8. PMID 15910781 DOI: 10.1016/J.Brainres.2005.03.017  0.56
2005 Gatto C, Helms JB, Prasse MC, Arnett KL, Milanick MA. Kinetic characterization of tetrapropylammonium inhibition reveals how ATP and Pi alter access to the Na+-K+-ATPase transport site. American Journal of Physiology. Cell Physiology. 289: C302-11. PMID 15788490 DOI: 10.1152/Ajpcell.00043.2005  0.56
2005 Kokubo H, Saido TC, Iwata N, Helms JB, Shinohara R, Yamaguchi H. Part of membrane-bound Abeta exists in rafts within senile plaques in Tg2576 mouse brain. Neurobiology of Aging. 26: 409-18. PMID 15653169 DOI: 10.1016/j.neurobiolaging.2004.04.008  0.56
2004 van der Sanden MH, Meems H, Houweling M, Helms JB, Vaandrager AB. Induction of CCAAT/enhancer-binding protein (C/EBP)-homologous protein/growth arrest and DNA damage-inducible protein 153 expression during inhibition of phosphatidylcholine synthesis is mediated via activation of a C/EBP-activating transcription factor-responsive element. The Journal of Biological Chemistry. 279: 52007-15. PMID 15466475 DOI: 10.1074/jbc.M405577200  0.56
2004 Serrano RL, Kuhn A, Hendricks A, Helms JB, Sinning I, Groves MR. Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. Journal of Molecular Biology. 339: 173-83. PMID 15123429 DOI: 10.1016/j.jmb.2004.03.015  0.56
2004 Helms JB, Arnett KL, Gatto C, Milanick MA. Bretylium, an organic quaternary amine, inhibits the Na,K-ATPase by binding to the extracellular K-site. Blood Cells, Molecules & Diseases. 32: 394-400. PMID 15121098 DOI: 10.1016/J.Bcmd.2004.01.013  0.56
2004 Groves MR, Kuhn A, Hendricks A, Radke S, Serrano RL, Helms JB, Sinning I. Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains. Acta Crystallographica. Section D, Biological Crystallography. 60: 730-2. PMID 15039568 DOI: 10.1107/S0907444904002136  0.56
2004 Helms JB, Zurzolo C. Lipids as targeting signals: lipid rafts and intracellular trafficking. Traffic (Copenhagen, Denmark). 5: 247-54. PMID 15030566 DOI: 10.1111/J.1600-0854.2004.0181.X  0.56
2004 Bleijerveld OB, Klein W, Vaandrager AB, Helms JB, Houweling M. Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol. The Biochemical Journal. 379: 711-9. PMID 14759225 DOI: 10.1042/BJ20031422  0.56
2003 Stüven E, Porat A, Shimron F, Fass E, Kaloyanova D, Brügger B, Wieland FT, Elazar Z, Helms JB. Intra-Golgi protein transport depends on a cholesterol balance in the lipid membrane. The Journal of Biological Chemistry. 278: 53112-22. PMID 14561753 DOI: 10.1074/Jbc.M300402200  0.56
2003 Kokubo H, Helms JB, Ohno-Iwashita Y, Shimada Y, Horikoshi Y, Yamaguchi H. Ultrastructural localization of flotillin-1 to cholesterol-rich membrane microdomains, rafts, in rat brain tissue. Brain Research. 965: 83-90. PMID 12591123 DOI: 10.1016/S0006-8993(02)04140-9  0.56
2002 Eberle HB, Serrano RL, Füllekrug J, Schlosser A, Lehmann WD, Lottspeich F, Kaloyanova D, Wieland FT, Helms JB. Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex. Journal of Cell Science. 115: 827-38. PMID 11865038  0.56
2001 Gommel DU, Memon AR, Heiss A, Lottspeich F, Pfannstiel J, Lechner J, Reinhard C, Helms JB, Nickel W, Wieland FT. Recruitment to Golgi membranes of ADP-ribosylation factor 1 is mediated by the cytoplasmic domain of p23. The Embo Journal. 20: 6751-60. PMID 11726511 DOI: 10.1093/emboj/20.23.6751  0.56
2001 Gkantiragas I, Brügger B, Stüven E, Kaloyanova D, Li XY, Löhr K, Lottspeich F, Wieland FT, Helms JB. Sphingomyelin-enriched microdomains at the Golgi complex. Molecular Biology of the Cell. 12: 1819-33. PMID 11408588  0.56
2000 Brügger B, Sandhoff R, Wegehingel S, Gorgas K, Malsam J, Helms JB, Lehmann WD, Nickel W, Wieland FT. Evidence for segregation of sphingomyelin and cholesterol during formation of COPI-coated vesicles. The Journal of Cell Biology. 151: 507-18. PMID 11062253 DOI: 10.1083/jcb.151.3.507  0.56
2000 Fischer KD, Helms JB, Zhao L, Wieland FT. Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles. Methods (San Diego, Calif.). 20: 455-64. PMID 10720466 DOI: 10.1006/meth.2000.0958  0.56
1999 Zhao L, Helms JB, Brunner J, Wieland FT. GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23. The Journal of Biological Chemistry. 274: 14198-203. PMID 10318838 DOI: 10.1074/jbc.274.20.14198  0.56
1999 Gommel D, Orci L, Emig EM, Hannah MJ, Ravazzola M, Nickel W, Helms JB, Wieland FT, Sohn K. p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway. Febs Letters. 447: 179-85. PMID 10214941 DOI: 10.1016/S0014-5793(99)00246-X  0.56
1999 Reinhard C, Harter C, Bremser M, Brügger B, Sohn K, Helms JB, Wieland F. Receptor-induced polymerization of coatomer. Proceedings of the National Academy of Sciences of the United States of America. 96: 1224-8. PMID 9990005 DOI: 10.1073/pnas.96.4.1224  0.56
1998 Nickel W, Malsam J, Gorgas K, Ravazzola M, Jenne N, Helms JB, Wieland FT. Uptake by COPI-coated vesicles of both anterograde and retrograde cargo is inhibited by GTPgammaS in vitro. Journal of Cell Science. 111: 3081-90. PMID 9739081  0.56
1998 Helms JB, Helms-Brons D, Brügger B, Gkantiragas I, Eberle H, Nickel W, Nürnberg B, Gerdes HH, Wieland FT. A putative heterotrimeric G protein inhibits the fusion of COPI-coated vesicles. Segregation of heterotrimeric G proteins from COPI-coated vesicles. The Journal of Biological Chemistry. 273: 15203-8. PMID 9614134 DOI: 10.1074/jbc.273.24.15203  0.56
1997 Zhao L, Helms JB, Brügger B, Harter C, Martoglio B, Graf R, Brunner J, Wieland FT. Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit beta. Proceedings of the National Academy of Sciences of the United States of America. 94: 4418-23. PMID 9114004 DOI: 10.1073/pnas.94.9.4418  0.56
1997 Galas MC, Helms JB, Vitale N, Thiersé D, Aunis D, Bader MF. Regulated exocytosis in chromaffin cells. A potential role for a secretory granule-associated ARF6 protein. The Journal of Biological Chemistry. 272: 2788-93. PMID 9006918 DOI: 10.1074/jbc.272.5.2788  0.56
1996 Sohn K, Orci L, Ravazzola M, Amherdt M, Bremser M, Lottspeich F, Fiedler K, Helms JB, Wieland FT. A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding. The Journal of Cell Biology. 135: 1239-48. PMID 8947548 DOI: 10.1083/jcb.135.5.1239  0.56
1996 Nickel W, Helms JB, Kneusel RE, Wieland FT. Forskolin stimulates detoxification of brefeldin A. The Journal of Biological Chemistry. 271: 15870-3. PMID 8663452 DOI: 10.1074/jbc.271.27.15870  0.56
1995 Helms JB. Role of heterotrimeric GTP binding proteins in vesicular protein transport: indications for both classical and alternative G protein cycles. Febs Letters. 369: 84-8. PMID 7641891 DOI: 10.1016/0014-5793(95)00620-O  0.56
1993 Palmer DJ, Helms JB, Beckers CJM, Orci L, Rothman JE. Binding of coatomer to Golgi membranes requires ADP-ribosylation factor Journal of Biological Chemistry. 268: 12083-12089. PMID 8505331  0.56
1993 Helms JB, Palmer DJ, Rothman JE. Two distinct populations of ARF bound to Golgi membranes Journal of Cell Biology. 121: 751-760. PMID 8491770 DOI: 10.1083/Jcb.121.4.751  0.56
1993 Tanigawa G, Orci L, Amherdt M, Ravazzola M, Helms JB, Rothman JE. Hydrolysis of bound GTP by ARF protein triggers uncoating of golgi-derived COP-coated vesicles Journal of Cell Biology. 123: 1365-1371. PMID 8253837 DOI: 10.1083/Jcb.123.6.1365  0.56
1992 Helms JB, Rothman JE. Inhibition by brefeldin a of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF Nature. 360: 352-354. PMID 1448152 DOI: 10.1038/360352A0  0.56
1990 Helms JB, Karrenbauer A, Wirtz KW, Rothman JE, Wieland FT. Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin. The Journal of Biological Chemistry. 265: 20027-32. PMID 2246279  0.56
1987 van Amerongen A, Helms JB, van der Krift TP, Schutgens RB, Wirtz KW. Purification of nonspecific lipid transfer protein (sterol carrier protein 2) from human liver and its deficiency in livers from patients with cerebro-hepato-renal (Zellweger) syndrome. Biochimica Et Biophysica Acta. 919: 149-55. PMID 3555624 DOI: 10.1016/0005-2760(87)90201-3  0.56
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