Harriet C. Isom - Publications

Affiliations: 
Microbiology and Immunology Pennsylvania State University, State College, PA, United States 
Area:
Microbiology Biology, Physiology Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Moon MS, McDevitt EI, Zhu J, Stanley B, Krzeminski J, Amin S, Aliaga C, Miller TG, Isom HC. Elevated hepatic iron activates NF-E2-related factor 2-regulated pathway in a dietary iron overload mouse model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 74-85. PMID 22649188 DOI: 10.1093/Toxsci/Kfs193  0.414
2011 Moon MS, Kang BH, Krzeminski J, Amin S, Aliaga C, Zhu J, McDevitt EI, Kocher S, Richie JP, Isom HC. 3,5,5-trimethyl-hexanoyl-ferrocene diet protects mice from moderate transient acetaminophen-induced hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 348-58. PMID 21908766 DOI: 10.1093/Toxsci/Kfr231  0.372
2010 Moon MS, Richie JP, Isom HC. Iron potentiates acetaminophen-induced oxidative stress and mitochondrial dysfunction in cultured mouse hepatocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 119-27. PMID 20667997 DOI: 10.1093/Toxsci/Kfq230  0.387
2010 McDevitt E, Moon MS, Kocher S, Krzeminski J, Das A, Amin S, El-Bayoumy K, Isom HC. Abstract 1886: Selenium prevents specific iron-mediated hepatic cellular changes associated with antioxidant defense and proliferation Cancer Research. 70: 1886-1886. DOI: 10.1158/1538-7445.Am10-1886  0.399
2009 Isom HC, McDevitt EI, Moon MS. Elevated hepatic iron: a confounding factor in chronic hepatitis C. Biochimica Et Biophysica Acta. 1790: 650-62. PMID 19393721 DOI: 10.1016/J.Bbagen.2009.04.009  0.429
2009 Heipertz RA, Starkey JL, Miller TG, Hu J, Isom HC. trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase. Virology. 388: 57-67. PMID 19383566 DOI: 10.1016/J.Virol.2009.03.018  0.775
2009 Starkey JL, Chiari EF, Isom HC. Hepatitis B virus (HBV)-specific short hairpin RNA is capable of reducing the formation of HBV covalently closed circular (CCC) DNA but has no effect on established CCC DNA in vitro. The Journal of General Virology. 90: 115-26. PMID 19088280 DOI: 10.1099/Vir.0.004408-0  0.472
2008 Shan W, Palkar PS, Murray IA, McDevitt EI, Kennett MJ, Kang BH, Isom HC, Perdew GH, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. Toxicological Sciences : An Official Journal of the Society of Toxicology. 105: 418-28. PMID 18622026 DOI: 10.1093/Toxsci/Kfn142  0.354
2007 Heipertz RA, Miller TG, Kelley CM, Delaney WE, Locarnini SA, Isom HC. In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication. Journal of Virology. 81: 3068-76. PMID 17215289 DOI: 10.1128/Jvi.02341-06  0.784
2007 Isom HC, Heipertz RA, Miller TG, Kelley CM. The lamivudine resistant mutation rtM204I and its effect on HBV replication in vitro The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A72  0.752
2007 Moon MS, Stoehr S, McDevitt E, Isom H. Hepatic iron potentiates acetaminophen (APAP) induced mitochondrial permeability transition (MPT) and hepatotoxicity The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A189-D  0.729
2004 Isom HC, Abdelhamed AM, Bilello JP, Miller TG. Baculovirus-mediated gene transfer for the study of hepatitis B virus. Methods in Molecular Medicine. 96: 219-37. PMID 14762273 DOI: 10.1385/1-59259-670-3:219  0.755
2003 Stoehr SA, Isom HC. Gap junction-mediated intercellular communication in a long-term primary mouse hepatocyte culture system. Hepatology (Baltimore, Md.). 38: 1125-35. PMID 14578851 DOI: 10.1053/Jhep.2003.50418  0.729
2003 Iocca HA, Isom HC. Tumor necrosis factor-alpha acts as a complete mitogen for primary rat hepatocytes. The American Journal of Pathology. 163: 465-76. PMID 12875968 DOI: 10.1016/S0002-9440(10)63676-0  0.742
2003 Bilello JP, Cable EE, Myers RL, Isom HC. Role of paracellular junction complexes in baculovirus-mediated gene transfer to nondividing rat hepatocytes. Gene Therapy. 10: 733-49. PMID 12704412 DOI: 10.1038/Sj.Gt.3301937  0.696
2003 Bilello JP, Cable EE, Isom HC. Expression of E-cadherin and other paracellular junction genes is decreased in iron-loaded hepatocytes. The American Journal of Pathology. 162: 1323-38. PMID 12651624 DOI: 10.1016/S0002-9440(10)63928-4  0.709
2003 Chen RY, Edwards R, Shaw T, Colledge D, Delaney WE, Isom H, Bowden S, Desmond P, Locarnini SA. Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro. Hepatology (Baltimore, Md.). 37: 27-35. PMID 12500185 DOI: 10.1053/Jhep.2003.50012  0.42
2003 Abdelhamed AM, Kelley CM, Miller TG, Furman PA, Cable EE, Isom HC. Comparison of anti-hepatitis B virus activities of lamivudine and clevudine by a quantitative assay. Antimicrobial Agents and Chemotherapy. 47: 324-36. PMID 12499209 DOI: 10.1128/Aac.47.1.324-336.2003  0.788
2003 STOEHR S, BILELLO J, ISOM H. 1052 Decreased E-cadherin expression in an in vivo model of chronic iron overload Hepatology. 38: 662-662. DOI: 10.1016/S0270-9139(03)81090-X  0.704
2003 BILELLO J, ISOM H. 894 Expression of paracellular junction genes in iron-loaded hepatocytes Hepatology. 38: 590-590. DOI: 10.1016/S0270-9139(03)80935-7  0.681
2002 Abdelhamed AM, Kelley CM, Miller TG, Furman PA, Isom HC. Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment. Journal of Virology. 76: 8148-60. PMID 12134020 DOI: 10.1128/Jvi.76.16.8148-8160.2002  0.79
2002 Malecki EA, Cable EE, Isom HC, Connor JR. The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice. Biological Trace Element Research. 86: 73-84. PMID 12002662 DOI: 10.1385/Bter:86:1:73  0.305
2001 Bilello JP, Delaney WE, Boyce FM, Isom HC. Transient disruption of intercellular junctions enables baculovirus entry into nondividing hepatocytes. Journal of Virology. 75: 9857-71. PMID 11559819 DOI: 10.1128/Jvi.75.20.9857-9871.2001  0.695
2001 Chin R, Shaw T, Torresi J, Sozzi V, Trautwein C, Bock T, Manns M, Isom H, Furman P, Locarnini S. In vitro susceptibilities of wild-type or drug-resistant hepatitis B virus to (-)-beta-D-2,6-diaminopurine dioxolane and 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil. Antimicrobial Agents and Chemotherapy. 45: 2495-501. PMID 11502520 DOI: 10.1128/Aac.45.9.2495-2501.2001  0.365
2001 Delaney IV WE, Edwards R, Colledge D, Shaw T, Torresi J, Miller TG, Isom HC, Bock CT, Manns MP, Trautwein C, Locarnini S. Cross-resistance testing of antihepadnaviral compounds using novel recombinant baculoviruses which encode drug-resistant strains of hepatitis B virus Antimicrobial Agents and Chemotherapy. 45: 1705-1713. PMID 11353615 DOI: 10.1128/Aac.45.6.1705-1713.2001  0.419
2001 Chen RY, Desmond PV, Delaney WE, Colledge DL, Edwards RM, Isom HC, Locarnini SA. Precore hepatitis B virus carrying lamivudine resistant mutations are not associated with decreassed replication fitness and are sensitive to adefovir Gastroenterology. 120: A64. DOI: 10.1016/S0016-5085(08)80318-6  0.414
1999 Delaney WE, Miller TG, Isom HC. Use of the hepatitis B virus recombinant baculovirus-HepG2 system to study the effects of (-)-β-2',3'-dideoxy-3'-thiacytidine on replication of hepatitis B virus and accumulation of covalently closed circular DNA Antimicrobial Agents and Chemotherapy. 43: 2017-2026. PMID 10428929 DOI: 10.1128/Aac.43.8.2017  0.491
1998 Delaney WE, Isom HC. Hepatitis B virus replication in human HepG2 cells mediated by hepatitis B virus recombinant baculovirus Hepatology. 28: 1134-1146. PMID 9755254 DOI: 10.1002/Hep.510280432  0.493
1997 Cable EE, Isom HC. Exposure of primary rat hepatocytes in long-term DMSO culture to selected transition metals induces hepatocyte proliferation and formation of duct-like structures Hepatology. 26: 1444-1457. PMID 9397984 DOI: 10.1002/Hep.510260611  0.412
1996 Guilhot S, Miller T, Cornman G, Isom HC. Apoptosis induced by tumor necrosis factor-α in rat hepatocyte cell lines expressing hepatitis B virus American Journal of Pathology. 148: 801-814. PMID 8774135  0.308
1995 Kempe KC, Isom HC, Greene FE. Responsiveness of an SV40-immortalized hepatocyte cell line to growth hormone Biochemical Pharmacology. 49: 1091-1098. PMID 7748190 DOI: 10.1016/0006-2952(95)98506-5  0.301
1993 Serra R, Isom HC. Stimulation of DNA synthesis and protooncogene expression in primary rat hepatocytes in long-term DMSO culture. Journal of Cellular Physiology. 154: 543-53. PMID 8436603 DOI: 10.1002/Jcp.1041540313  0.328
1990 Isom HC, Yin CY. Guinea pig cytomegalovirus gene expression Current Topics in Microbiology and Immunology. 154: 101-121. PMID 2161318 DOI: 10.1007/978-3-642-74980-3_5  0.312
1989 Liao WS, Ma KT, Woodworth CD, Mengel L, Isom HC. Stimulation of the acute-phase response in simian virus 40-hepatocyte cell lines. Molecular and Cellular Biology. 9: 2779-86. PMID 2476657 DOI: 10.1128/Mcb.9.7.2779  0.378
1989 Patel NU, Jameel S, Isom H, Siddiqui A. Interactions between nuclear factors and the hepatitis B virus enhancer. Journal of Virology. 63: 5293-5301. DOI: 10.1128/Jvi.63.12.5293-5301.1989  0.412
1988 Cammisa HM, Isom HC, Greene FE. Hormonal regulation of pseudocholinesterase activity in cultured rat hepatocytes Endocrinology. 122: 991-996. PMID 3342764 DOI: 10.1210/Endo-122-3-991  0.319
1988 Woodworth CD, Kreider JW, Mengel L, Miller T, Meng YL, Isom HC. Tumorigenicity of simian virus 40-hepatocyte cell lines: effect of in vitro and in vivo passage on expression of liver-specific genes and oncogenes. Molecular and Cellular Biology. 8: 4492-501. PMID 2460744 DOI: 10.1128/Mcb.8.10.4492  0.376
1987 Woodworth CD, Isom HC. Transformation of differentiated rat hepatocytes with adenovirus and adenovirus DNA Journal of Virology. 61: 3570-3579. PMID 3669153 DOI: 10.1128/Jvi.61.11.3570-3579.1987  0.378
1987 Sha M, Griffith BP, Raveh D, Isom HC, Ward DC, Hsiung GD. Detection of guinea pig cytomegalovirus nucleic acids in cultured cells with biotin-labelled hybridization probes Virus Research. 6: 317-329. PMID 3031892 DOI: 10.1016/0168-1702(87)90064-5  0.31
1987 Woodworth CD, Isom HC. Regulation of albumin gene expression in a series of rat hepatocyte cell lines immortalized by simian virus 40 and maintained in chemically defined medium Molecular and Cellular Biology. 7: 3740-3748. PMID 2446120 DOI: 10.1128/Mcb.7.10.3740  0.332
1985 Isom HC, Secott T, Georgoff I, Woodworth C, Mummaw J. Maintenance of differentiated rat hepatocytes in primary culture Proceedings of the National Academy of Sciences of the United States of America. 82: 3252-3256. PMID 3858822 DOI: 10.1073/Pnas.82.10.3252  0.334
1984 Isom HC, Gao M, Wigdahl B. Characterization of guinea pig cytomegalovirus DNA Journal of Virology. 49: 426-436. PMID 6319742 DOI: 10.1128/Jvi.49.2.426-436.1984  0.312
1984 Isom HC, Georgoff I. Quantitative assay for albumin-producing liver cells after simian virus 40 transformation of rat hepatocytes maintained in chemically defined medium Proceedings of the National Academy of Sciences of the United States of America. 81: 6378-6382. PMID 6093099 DOI: 10.1073/Pnas.81.20.6378  0.361
1983 Isom HC, Mummaw J, Kreider JW. Malignant transformation of guinea pig cells after exposure to ultraviolet-irradiated guinea pig cytomegalovirus. Virology. 126: 693-700. PMID 6305008 DOI: 10.1016/S0042-6822(83)80025-7  0.302
1983 Isom HC, Liao WS, Taylor JM, Willwerth GE, Eadline TS. Rapid and selective shutoff of plasma protein production in herpes simplex virus type 2-infected hepatoma cells. Virology. 126: 548-62. PMID 6190309 DOI: 10.1016/S0042-6822(83)80012-9  0.331
1982 Wigdahl BL, Isom HC, De Clercq E, Rapp F. Activation of herpes simplex virus (HSV) type 1 genome by temperature-sensitive mutants of HSV type 2. Virology. 116: 468-79. PMID 6278723 DOI: 10.1016/0042-6822(82)90140-4  0.388
1981 Wigdahl BL, Isom HC, Rapp F. Repression and activation of the genome of herpes simplex viruses in human cells Proceedings of the National Academy of Sciences of the United States of America. 78: 6522-6526. PMID 6273875 DOI: 10.1073/Pnas.78.10.6522  0.382
1981 Colberg-Poley AM, Isom HC, Rapp F. Involvement of an early human cytomegalovirus function in reactivation of quiescent herpes simplex virus type 2 Journal of Virology. 37: 1051-1059. PMID 6262523 DOI: 10.1128/Jvi.37.3.1051-1059.1981  0.384
1980 Isom HC. DNA synthesis in isolated hepatocytes infected with herpesviruses Virology. 103: 199-216. PMID 6245526 DOI: 10.1016/0042-6822(80)90138-5  0.391
1980 Isom HC, Tevethia MJ, Taylor JM. Properties of simian virus 40 (SV40)-transformed hepatocytes Annals of the New York Academy of Sciences. 391-392. PMID 6111975 DOI: 10.1111/J.1749-6632.1980.Tb29545.X  0.325
1980 Isom HC, Tevethia MJ, Taylor JM. Transformation of isolated rat hepatocytes with simian virus 40 Journal of Cell Biology. 85: 651-659. PMID 6104673 DOI: 10.1083/Jcb.85.3.651  0.355
1979 Colberg-Poley AM, Isom H, Rapp F. Experimental HSV Latency Using Phosphonoacetic Acid Proceedings of the Society For Experimental Biology and Medicine. 162: 235-237. PMID 504235 DOI: 10.3181/00379727-162-40655  0.35
1979 Colberg-Poley AM, Isom HC, Rapp F. Reactivation of herpes simplex virus type 2 from a quiescent state by human cytomegalovirus Proceedings of the National Academy of Sciences of the United States of America. 76: 5948-5951. PMID 230494 DOI: 10.1073/Pnas.76.11.5948  0.348
1979 Isom HC, Pegg AE. Inhibition of cytomegalovirus-stimulated human cell ornithine decarboxylase by α-difluoromethylornithine Bba Section Nucleic Acids and Protein Synthesis. 564: 402-413. PMID 227464 DOI: 10.1016/0005-2787(79)90031-5  0.302
1979 Isom HC. Stimulation of ornithine decarboxylase by human cytomegalovirus Journal of General Virology. 42: 265-278. PMID 217956 DOI: 10.1099/0022-1317-42-2-265  0.345
1978 Isom H, Colberg A, Reed C, Rapp F. Conditions required for induction of murine p30 by herpes simplex virus. International Journal of Cancer. 22: 22-7. PMID 210128 DOI: 10.1002/Ijc.2910220106  0.354
1978 Isom HC, Pizer LI. Growth dependence of phosphoglyceric acid dehydrogenase activity in cultured rat liver cells Journal of Cellular Physiology. 95: 139-150. PMID 206565 DOI: 10.1002/Jcp.1040950203  0.337
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