Michael L. Dustin - Publications

Affiliations: 
Basic Medical Science New York University, New York, NY, United States 
Area:
Immunology, Microbiology Biology

389 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, ... ... Dustin ML, et al. Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature Immunology. PMID 38561495 DOI: 10.1038/s41590-024-01802-3  0.431
2024 Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, ... ... Dustin ML, et al. Transmembrane domain-driven PD-1 dimers mediate T cell inhibition. Science Immunology. 9: eade6256. PMID 38457513 DOI: 10.1126/sciimmunol.ade6256  0.784
2024 Kvalvaag A, Dustin ML. Clathrin controls bidirectional communication between T cells and antigen presenting cells. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300230. PMID 38412391 DOI: 10.1002/bies.202300230  0.457
2023 Patel A, Andre V, Eguiguren SB, Barton MI, Burton J, Denham EM, Pettmann J, Mørch AM, Kutuzov MA, Siller-Farfán JA, Dustin ML, van der Merwe PA, Dushek O. Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors. The Embo Journal. 43: 132-150. PMID 38177315 DOI: 10.1038/s44318-023-00012-1  0.847
2023 Lui VG, Hoenig M, Cabrera-Martinez B, Baxter RM, Garcia-Perez JE, Bailey O, Acharya A, Lundquist K, Capera J, Matusewicz P, Hartl FA, D'Abramo M, Alba J, Jacobsen EM, Niewolik D, ... ... Dustin ML, et al. A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation. The Journal of Experimental Medicine. 221. PMID 37962568 DOI: 10.1084/jem.20230927  0.454
2023 Dustin ML. Recent advances in understanding TCR signaling: a synaptic perspective. Faculty Reviews. 12: 25. PMID 37900153 DOI: 10.12703/r/12-25  0.36
2023 Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML. Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells. Biophysical Journal. PMID 37596785 DOI: 10.1016/j.bpj.2023.08.011  0.43
2023 Zhou XMM, Mørch AM, Dustin ML. Curving out a new path: CD28/B7 cis interactions. Immunity. 56: 1155-1157. PMID 37315528 DOI: 10.1016/j.immuni.2023.05.002  0.807
2023 Ogbechi J, Wright HL, Balint S, Topping LM, Kristina Z, Huang YS, Pantazi E, Swart M, Windell D, Marin E, Wempe MF, Endou H, Thomas AM, Filer A, Stone TW, ... ... Dustin ML, et al. LAT1 enables T cell activation under inflammatory conditions. Journal of Autoimmunity. 138: 103031. PMID 37229811 DOI: 10.1016/j.jaut.2023.103031  0.407
2023 Jainarayanan A, Mouroug-Anand N, Arbe-Barnes EH, Bush AJ, Bashford-Rogers R, Frampton A, Heij L, Middleton M, Dustin ML, Abu-Shah E, Sivakumar S. Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform distinct functional states within the regulatory and cytotoxic T cells. Iscience. 26: 106324. PMID 36968070 DOI: 10.1016/j.isci.2023.106324  0.386
2023 Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML. Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211368120. PMID 36730202 DOI: 10.1073/pnas.2211368120  0.449
2022 Mørch AM, Schneider F, Jenkins E, Santos AM, Fraser SE, Davis SJ, Dustin ML. The kinase occupancy of T cell coreceptors reconsidered. Proceedings of the National Academy of Sciences of the United States of America. 119: e2213538119. PMID 36454761 DOI: 10.1073/pnas.2213538119  0.83
2022 Lanna A, Vaz B, D'Ambra C, Valvo S, Vuotto C, Chiurchiù V, Devine O, Sanchez M, Borsellino G, Akbar AN, De Bardi M, Gilroy DW, Dustin ML, Blumer B, Karin M. An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory. Nature Cell Biology. PMID 36109671 DOI: 10.1038/s41556-022-00991-z  0.403
2022 Céspedes PF, Jainarayanan A, Fernández-Messina L, Valvo S, Saliba DG, Kurz E, Kvalvaag A, Chen L, Ganskow C, Colin-York H, Fritzsche M, Peng Y, Dong T, Johnson E, Siller-Farfán JA, ... ... Dustin ML, et al. T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles. Nature Communications. 13: 3460. PMID 35710644 DOI: 10.1038/s41467-022-31160-3  0.408
2022 Jing Z, McCarron MJ, Dustin ML, Fooksman DR. Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength. Cell Reports. 39: 110763. PMID 35508132 DOI: 10.1016/j.celrep.2022.110763  0.369
2022 Céspedes PF, Dustin ML. Preparation of Bead-supported Lipid Bilayers to Study the Particulate Output of T Cell Immune Synapses. Journal of Visualized Experiments : Jove. PMID 35435908 DOI: 10.3791/63130  0.453
2022 Vardhana S, Dustin ML. Magnesium for T cells: strong to the finish! Trends in Immunology. PMID 35260350 DOI: 10.1016/j.it.2022.02.004  0.738
2022 Goyette J, Depoil D, Yang Z, Isaacson SA, Allard J, van der Merwe PA, Gaus K, Dustin ML, Dushek O. Dephosphorylation accelerates the dissociation of ZAP70 from the T cell receptor. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35197288 DOI: 10.1073/pnas.2116815119  0.341
2022 Al-Aghbar MA, Jainarayanan AK, Dustin ML, Roffler SR. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. Communications Biology. 5: 40. PMID 35017678 DOI: 10.1038/s42003-021-02995-1  0.466
2021 Felce SL, Farnie G, Dustin ML, Felce JH. RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line. Wellcome Open Research. 5: 42. PMID 36865034 DOI: 10.12688/wellcomeopenres.15748.2  0.391
2021 Correa K, Dustin ML. Locked and loaded: strong TCR signaling primes anti-PD-1 therapy. Trends in Immunology. 42: 1066-1068. PMID 34772621 DOI: 10.1016/j.it.2021.10.014  0.353
2021 Velas L, Brameshuber M, Huppa JB, Kurz E, Dustin ML, Zelger P, Jesacher A, Schütz GJ. Three-Dimensional Single Molecule Localization Microscopy Reveals the Topography of the Immunological Synapse at Isotropic Precision below 15 nm. Nano Letters. 21: 9247-9255. PMID 34709845 DOI: 10.1021/acs.nanolett.1c03160  0.327
2021 Siokis A, Robert PA, Demetriou P, Kvalvaag A, Valvo S, Mayya V, Dustin ML, Meyer-Hermann M. Characterization of mechanisms positioning costimulatory complexes in immune synapses. Iscience. 24: 103100. PMID 34622155 DOI: 10.1016/j.isci.2021.103100  0.313
2021 Dustin ML. Tireless surveillance by exhausted T cells. The Journal of Clinical Investigation. 131. PMID 34523616 DOI: 10.1172/JCI152382  0.394
2021 Cassioli C, Onnis A, Finetti F, Capitani N, Brunetti J, Compeer EB, Niederlova V, Stepanek O, Dustin ML, Baldari CT. The Bardet-Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly. Journal of Cell Science. 134. PMID 34423835 DOI: 10.1242/jcs.258462  0.332
2021 Lanz AL, Masi G, Porciello N, Cohnen A, Cipria D, Prakaash D, Bálint Š, Raggiaschi R, Galgano D, Cole DK, Lepore M, Dushek O, Dustin ML, Sansom MSP, Kalli AC, et al. Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation. Cell Reports. 36: 109531. PMID 34380025 DOI: 10.1016/j.celrep.2021.109531  0.396
2021 Cassioli C, Balint S, Compeer EB, Felce JH, Gamberucci A, Della Bella C, Felce SL, Brunetti J, Valvo S, Pende D, D'Elios MM, Moretta L, Dustin ML, Baldari CT. Increasing LFA-1 Expression Enhances Immune Synapse Architecture and T Cell Receptor Signaling in Jurkat E6.1 Cells. Frontiers in Cell and Developmental Biology. 9: 673446. PMID 34368126 DOI: 10.3389/fcell.2021.673446  0.403
2021 Lanz AL, Masi G, Porciello N, Cohnen A, Cipria D, Prakaash D, Bálint Š, Raggiaschi R, Galgano D, Cole DK, Lepore M, Dushek O, Dustin ML, Sansom MSP, Kalli AC, et al. Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation. Cell Reports. 36: 109375. PMID 34260912 DOI: 10.1016/j.celrep.2021.109375  0.418
2021 Cassioli C, Onnis A, Finetti F, Capitani N, Brunetti J, Compeer EB, Niederlova V, Stepanek O, Dustin ML, Baldari CT. The Bardet-Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly. Journal of Cell Science. PMID 34251457 DOI: 10.1242/jcs.258462  0.333
2021 Pettmann J, Huhn A, Abu Shah E, Kutuzov MA, Wilson DB, Dustin ML, Davis SJ, van der Merwe PA, Dushek O. The discriminatory power of the T cell receptor. Elife. 10. PMID 34030769 DOI: 10.7554/eLife.67092  0.615
2021 Sivakumar S, Abu-Shah E, Ahern DJ, Arbe-Barnes EH, Jainarayanan AK, Mangal N, Reddy S, Rendek A, Easton A, Kurz E, Silva M, Soonawalla Z, Heij LR, Bashford-Rogers R, Middleton MR, ... Dustin ML, et al. Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer. Cancers. 13. PMID 33917832 DOI: 10.3390/cancers13081776  0.38
2020 Felce JH, Parolini L, Sezgin E, Céspedes PF, Korobchevskaya K, Jones M, Peng Y, Dong T, Fritzsche M, Aarts D, Frater J, Dustin ML. Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse. Frontiers in Cell and Developmental Biology. 8: 608484. PMID 33537301 DOI: 10.3389/fcell.2020.608484  0.436
2020 Daley D, Zambirinis CP, Seifert L, Akkad N, Mohan N, Werba G, Barilla R, Torres-Hernandez A, Hundeyin M, Kumar Mani VR, Avanzi A, Tippens D, Narayanan R, Jang JE, Newman E, ... ... Dustin ML, et al. γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation. Cell. 183: 1134-1136. PMID 33186522 DOI: 10.1016/j.cell.2020.10.041  0.399
2020 Mørch AM, Bálint Š, Santos AM, Davis SJ, Dustin ML. Coreceptors and TCR Signaling - the Strong and the Weak of It. Frontiers in Cell and Developmental Biology. 8: 597627. PMID 33178706 DOI: 10.3389/fcell.2020.597627  0.842
2020 Belardi B, Son S, Felce JH, Dustin ML, Fletcher DA. Cell-cell interfaces as specialized compartments directing cell function. Nature Reviews. Molecular Cell Biology. PMID 33093672 DOI: 10.1038/s41580-020-00298-7  0.357
2020 Demetriou P, Abu-Shah E, Valvo S, McCuaig S, Mayya V, Kvalvaag A, Starkey T, Korobchevskaya K, Lee LYW, Friedrich M, Mann E, Kutuzov MA, Morotti M, Wietek N, Rada H, ... ... Dustin ML, et al. A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals. Nature Immunology. PMID 32929275 DOI: 10.1038/S41590-020-0770-X  0.438
2020 Céspedes PF, Beckers D, Dustin ML, Sezgin E. Model membrane systems to reconstitute immune cell signaling. The Febs Journal. PMID 32681663 DOI: 10.1111/Febs.15488  0.337
2020 Harrison TE, Mørch AM, Felce JH, Sakoguchi A, Reid AJ, Arase H, Dustin ML, Higgins MK. Structural basis for RIFIN-mediated activation of LILRB1 in malaria. Nature. PMID 32650338 DOI: 10.1038/S41586-020-2530-3  0.803
2020 Balint Š, Müller S, Fischer R, Kessler BM, Harkiolaki M, Valitutti S, Dustin ML. Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells. Science (New York, N.Y.). PMID 32381591 DOI: 10.1126/Science.Aay9207  0.392
2020 Coomer CA, Carlon-Andres I, Iliopoulou M, Dustin ML, Compeer EB, Compton AA, Padilla-Parra S. Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion. Plos Pathogens. 16: e1008359. PMID 32084246 DOI: 10.1371/Journal.Ppat.1008359  0.332
2020 Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML. Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity. Scientific Reports. 10: 3317. PMID 32076101 DOI: 10.1038/S41598-020-60485-6  0.42
2020 Kumari S, Mak M, Poh YC, Tohme M, Watson N, Melo M, Janssen E, Dustin M, Geha R, Irvine DJ. Cytoskeletal tension actively sustains the migratory T-cell synaptic contact. The Embo Journal. e102783. PMID 31894880 DOI: 10.15252/Embj.2019102783  0.514
2020 Dustin ML, Stow JL. Decision letter: Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse Elife. DOI: 10.7554/Elife.58065.Sa1  0.358
2020 Dustin ML. Decision letter: CD56 regulates human NK cell cytotoxicity through Pyk2 Elife. DOI: 10.7554/Elife.57346.Sa1  0.395
2020 Cannon J, Dustin ML. Decision letter: Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo Elife. DOI: 10.7554/Elife.53933.Sa1  0.392
2020 Felce SL, Farnie G, Dustin ML, Felce JH. RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line Wellcome Open Research. 5: 42. DOI: 10.12688/wellcomeopenres.15748.1  0.39
2020 Felce JH, Dustin ML. Single-Molecule Imaging Reveals Chemokine Receptor Contributions to the T Cell Immunological Synapse Biophysical Journal. 118: 97a. DOI: 10.1016/J.Bpj.2019.11.692  0.464
2019 Sivakumar S, Abu-Shah E, Ahern D, Mangal N, Reddy S, Rendek A, Silva M, Soonawalla Z, Middleton M, Dustin M. The T cell architecture of pancreatic ductal adenocarcinoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 30: iv64. PMID 32085242 DOI: 10.1093/Annonc/Mdz155.233  0.443
2019 Abu Shah E, Demetriou P, Bálint Š, Mayya V, Kutuzov MA, Dushek O, Dustin ML. A tissue-like platform for studying engineered quiescent human T-cells' interactions with dendritic cells. Elife. 8. PMID 31552826 DOI: 10.7554/Elife.48221  0.541
2019 Saliba DG, Cespedes-Donoso PF, Bálint Š, Compeer EB, Korobchevskaya K, Valvo S, Mayya V, Kvalvaag A, Peng Y, Dong T, Tognoli ML, O'Neill E, Bonham S, Fischer R, Kessler BM, ... Dustin ML, et al. Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T-cells. Elife. 8. PMID 31469364 DOI: 10.7554/Elife.47528  0.537
2019 Mintz MA, Felce JH, Chou MY, Mayya V, Xu Y, Shui JW, An J, Li Z, Marson A, Okada T, Ware CF, Kronenberg M, Dustin ML, Cyster JG. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. PMID 31204070 DOI: 10.1016/J.Immuni.2019.05.022  0.504
2019 Mayya V, Judokusumo E, Abu-Shah E, Neiswanger W, Sachar C, Depoil D, Kam LC, Dustin ML. Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts. Journal of Immunology (Baltimore, Md. : 1950). PMID 31201237 DOI: 10.4049/Jimmunol.1801687  0.507
2019 Dustin ML, Scotet E, Olive D. An X-ray Vision for Phosphoantigen Recognition. Immunity. 50: 1026-1028. PMID 30995494 DOI: 10.1016/J.Immuni.2019.03.015  0.317
2019 Dustin ML. Integrins and Their Role in Immune Cell Adhesion. Cell. PMID 30952447 DOI: 10.1016/J.Cell.2019.03.038  0.36
2019 Brown MH, Dustin ML. Retraction: Steering CAR T Cells into Solid Tumors. N Engl J Med 2019;380:289-91. The New England Journal of Medicine. PMID 30786181 DOI: 10.1056/Nejmc1902526  0.438
2019 Brown MH, Dustin ML. Steering CAR T Cells into Solid Tumors. The New England Journal of Medicine. 380: 289-291. PMID 30650328 DOI: 10.1056/Nejmcibr1811991  0.45
2019 Abu-Shah E, Demetriou P, Bálint Š, Mayya V, Kutuzov MA, Dushek O, Dustin ML. Author response: A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells Elife. DOI: 10.7554/Elife.48221.Sa2  0.406
2019 Saliba DG, Céspedes-Donoso PF, Bálint Š, Compeer EB, Korobchevskaya K, Valvo S, Mayya V, Kvalvaag A, Peng Y, Dong T, Tognoli M, O'Neill E, Bonham S, Fischer R, Kessler BM, ... Dustin ML, et al. Author response: Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells Elife. DOI: 10.7554/Elife.47528.035  0.505
2019 Dustin ML. Decision letter: Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion Elife. DOI: 10.7554/Elife.45789.043  0.427
2019 Dustin ML. Decision letter: A composition-dependent molecular clutch between T cell signaling condensates and actin Elife. DOI: 10.7554/Elife.42695.060  0.43
2019 Sivakumar S, Shah EA, Ahern D, Mangal N, Reddy S, Rendek A, Soonawalla Z, Silva M, Middleton M, Dustin M. Abstract B52: The T-cell architecture of pancreatic ductal adenocarcinoma Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B52  0.49
2018 Felce JH, Sezgin E, Wane M, Brouwer H, Dustin ML, Eggeling C, Davis SJ. CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity. Science Signaling. 11. PMID 30563863 DOI: 10.1126/Scisignal.Aat0756  0.645
2018 Beilin C, Choudhuri K, Bouma G, Malinova D, Llodra J, Stokes DL, Shimaoka M, Springer TA, Dustin ML, Thrasher AJ, Burns SO. Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse. Wellcome Open Research. 3: 84. PMID 30483599 DOI: 10.12688/wellcomeopenres.14493.2  0.544
2018 Dushek O, Dustin ML. CD8 helps TCR catch slippery self pMHC. Nature Immunology. 19: 1280-1281. PMID 30420625 DOI: 10.1038/S41590-018-0261-5  0.344
2018 Muller J, Baeyens A, Dustin ML. Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function. Advances in Immunology. 140: 21-57. PMID 30366518 DOI: 10.1016/Bs.Ai.2018.08.001  0.497
2018 Jenkins E, Santos AM, O'Brien-Ball C, Felce JH, Wilcock MJ, Hatherley D, Dustin ML, Davis SJ, Eggeling C, Sezgin E. Reconstitution of immune cell interactions in free-standing membranes. Journal of Cell Science. PMID 30209137 DOI: 10.1242/Jcs.219709  0.628
2018 Felce JH, Dustin ML. Natural killers shed attachments to kill again. The Journal of Cell Biology. PMID 30108125 DOI: 10.1083/Jcb.201807105  0.422
2018 McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, ... ... Dustin ML, et al. The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease. The Journal of Clinical Investigation. PMID 30106752 DOI: 10.1172/Jci95713  0.465
2018 Siokis A, Robert PA, Demetriou P, Dustin ML, Meyer-Hermann M. F-Actin-Driven CD28-CD80 Localization in the Immune Synapse. Cell Reports. 24: 1151-1162. PMID 30067972 DOI: 10.1016/J.Celrep.2018.06.114  0.48
2018 Sanchez-Blanco C, Clarke F, Cornish GH, Depoil D, Thompson SJ, Dai X, Rawlings DJ, Dustin ML, Zamoyska R, Cope AP, Purvis HA. Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses. Journal of Autoimmunity. PMID 30054208 DOI: 10.1016/J.Jaut.2018.07.008  0.566
2018 Newton RH, Shrestha S, Sullivan JM, Yates KB, Compeer EB, Ron-Harel N, Blazar BR, Bensinger SJ, Haining WN, Dustin ML, Campbell DJ, Chi H, Turka LA. Maintenance of CD4 T cell fitness through regulation of Foxo1. Nature Immunology. PMID 29988091 DOI: 10.1038/S41590-018-0157-4  0.517
2018 Velázquez P, Williams C, Leiner I, Pamer EG, Dustin ML. Distinct behavior of myelomonocytic cells and CD8 T cells underlies the hepatic response to . Wellcome Open Research. 3: 48. PMID 29862325 DOI: 10.12688/wellcomeopenres.12941.1  0.61
2018 Cai H, Muller J, Depoil D, Mayya V, Sheetz MP, Dustin ML, Wind SJ. Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering. Nature Nanotechnology. PMID 29713075 DOI: 10.1038/S41565-018-0113-3  0.51
2018 Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, et al. Capturing resting T cells: the perils of PLL. Nature Immunology. PMID 29476188 DOI: 10.1038/S41590-018-0048-8  0.509
2018 Arbulo-Echevarria MM, Narbona-Sánchez I, Fernandez-Ponce CM, Vico-Barranco I, Rueda-Ygueravide MD, Dustin ML, Miazek A, Duran-Ruiz MC, García-Cózar F, Aguado E. A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling. Frontiers in Immunology. 9: 115. PMID 29456532 DOI: 10.3389/Fimmu.2018.00115  0.486
2018 Mayya V, Judokusumo E, Abu Shah E, Peel CG, Neiswanger W, Depoil D, Blair DA, Wiggins CH, Kam LC, Dustin ML. Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse. Cell Reports. 22: 340-349. PMID 29320731 DOI: 10.1016/J.Celrep.2017.12.052  0.537
2018 Dustin ML, Turley S. Decision letter: High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node Elife. DOI: 10.7554/Elife.41239.017  0.319
2018 Felce J, Sezgin E, Wane M, Dustin M, Eggeling C, Davis S. Triggering of the High-Affinity IgE Receptor in an Aggregation-Independent Manner Biophysical Journal. 114: 108a-109a. DOI: 10.1016/J.Bpj.2017.11.630  0.522
2017 Azoulay-Alfaguter I, Strazza M, Peled M, Novak HK, Muller J, Dustin ML, Mor A. The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse. Science Signaling. 10. PMID 28790195 DOI: 10.1126/Scisignal.Aal2880  0.545
2017 Jang JE, Hajdu CH, Liot C, Miller G, Dustin ML, Bar-Sagi D. Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer. Cell Reports. 20: 558-571. PMID 28723561 DOI: 10.1016/J.Celrep.2017.06.062  0.51
2017 Papa I, Saliba D, Ponzoni M, Bustamante S, Canete PF, Gonzalez-Figueroa P, McNamara HA, Valvo S, Grimbaldeston M, Sweet RA, Vohra H, Cockburn IA, Meyer-Hermann M, Dustin ML, Doglioni C, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. PMID 28700579 DOI: 10.1038/Nature23013  0.465
2017 Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML. Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity. Scientific Reports. 7: 4258. PMID 28652577 DOI: 10.1038/S41598-017-04053-5  0.483
2017 Mendoza A, Fang V, Chen C, Serasinghe M, Verma A, Muller J, Chaluvadi VS, Dustin ML, Hla T, Elemento O, Chipuk JE, Schwab SR. Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. Nature. PMID 28538737 DOI: 10.1038/Nature22352  0.508
2017 Bálint Š, Dustin ML. Localizing order to boost signaling. Elife. 6. PMID 28358300 DOI: 10.7554/Elife.25375  0.337
2017 Lopes FB, Bálint Š, Valvo S, Felce JH, Hessel EM, Dustin ML, Davis DM. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. The Journal of Cell Biology. PMID 28289091 DOI: 10.1083/Jcb.201608094  0.317
2017 Valvo S, Mayya V, Seraia E, Afrose J, Novak-Kotzer H, Ebner D, Dustin ML. Comprehensive Analysis of Immunological Synapse Phenotypes Using Supported Lipid Bilayers. Methods in Molecular Biology (Clifton, N.J.). 1584: 423-441. PMID 28255717 DOI: 10.1007/978-1-4939-6881-7_26  0.309
2017 Cai H, Depoil D, Muller J, Sheetz MP, Dustin ML, Wind SJ. Spatial Control of Biological Ligands on Surfaces Applied to T Cell Activation. Methods in Molecular Biology (Clifton, N.J.). 1584: 307-331. PMID 28255709 DOI: 10.1007/978-1-4939-6881-7_18  0.349
2017 Dustin ML, Baldari CT. The Immune Synapse: Past, Present, and Future. Methods in Molecular Biology (Clifton, N.J.). 1584: 1-5. PMID 28255692 DOI: 10.1007/978-1-4939-6881-7_1  0.429
2016 Fu W, Hu W, Shi L, Mundra JJ, Xiao G, Dustin ML, Liu CJ. Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28011648 DOI: 10.1096/Fj.201601134R  0.327
2016 Dustin ML. Help to go: T cells transfer CD40L to antigen-presenting B cells. European Journal of Immunology. PMID 28004382 DOI: 10.1002/Eji.201646786  0.504
2016 Schmid EM, Bakalar MH, Choudhuri K, Weichsel J, Ann H, Geissler PL, Dustin ML, Fletcher DA. Size-dependent protein segregation at membrane interfaces. Nature Physics. 12: 704-711. PMID 27980602 DOI: 10.1038/Nphys3678  0.341
2016 Dustin ML. Complement Receptors in Myeloid Cell Adhesion and Phagocytosis. Microbiology Spectrum. 4. PMID 27809953 DOI: 10.1128/Microbiolspec.Mchd-0034-2016  0.366
2016 Deng J, Mitsuki YY, Shen G, Ray J, Cicala C, Arthos J, Dustin ML, Hioe CE. HIV envelope gp120 alters T-cell receptor mobilization in the immunological synapse of uninfected CD4 T cells and augments the T cell activation. Journal of Virology. PMID 27630246 DOI: 10.1128/Jvi.01532-16  0.511
2016 Dustin ML, Peel CG. Force Bistability in Adhesion Switch. Biophysical Journal. 111: 900-901. PMID 27602717 DOI: 10.1016/J.Bpj.2016.07.031  0.339
2016 Daley D, Zambirinis CP, Seifert L, Akkad N, Mohan N, Werba G, Barilla R, Torres-Hernandez A, Hundeyin M, Mani VR, Avanzi A, Tippens D, Narayanan R, Jang JE, Newman E, ... ... Dustin ML, et al. γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation. Cell. PMID 27569912 DOI: 10.1016/J.Cell.2016.07.046  0.54
2016 Lanna A, Dustin ML. Mitochondrial fusion fuels T cell memory. Cell Research. PMID 27514702 DOI: 10.1038/Cr.2016.94  0.357
2016 Dustin ML, Choudhuri K. Signaling and Polarized Communication Across the T Cell Immunological Synapse. Annual Review of Cell and Developmental Biology. PMID 27501450 DOI: 10.1146/Annurev-Cellbio-100814-125330  0.538
2016 Chen HH, Händel N, Ngeow J, Muller J, Hühn M, Yang HT, Heindl M, Berbers RM, Hegazy AN, Kionke J, Yehia L, Sack U, Bläser F, Rensing-Ehl A, Reifenberger J, ... ... Dustin ML, et al. Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. The Journal of Allergy and Clinical Immunology. PMID 27477328 DOI: 10.1016/J.Jaci.2016.03.059  0.343
2016 Mayya V, Dustin ML. What Scales the T Cell Response? Trends in Immunology. PMID 27364960 DOI: 10.1016/J.It.2016.06.005  0.487
2016 Santos LC, Blair DA, Kumari S, Cammer M, Iskratsch T, Herbin O, Alexandropoulos K, Dustin ML, Sheetz MP. Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability. Immunology and Cell Biology. PMID 27359298 DOI: 10.1038/Icb.2016.61  0.475
2016 Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, ... ... Dustin ML, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. The Journal of Clinical Investigation. PMID 27294527 DOI: 10.1172/Jci85796  0.385
2016 Dustin ML, Kam LC. Tapping out a mechanical code for T cell triggering. The Journal of Cell Biology. 213: 501-503. PMID 27269063 DOI: 10.1083/Jcb.201605072  0.482
2016 Padilla-Parra S, Dustin ML. Actin Dynamics and HIV-1 Entry. Trends in Molecular Medicine. PMID 27151391 DOI: 10.1016/J.Molmed.2016.03.007  0.357
2016 Dustin ML, Muller J. CELL SIGNALING. Liquidity in immune cell signaling. Science (New York, N.Y.). 352: 516-7. PMID 27126023 DOI: 10.1126/Science.Aaf8179  0.349
2016 Hu J, Gondarenko A, Dang A, Bashour K, O'Connor R, Lee S, Liapis A, Ghassemi S, Milone M, Sheetz MP, Dustin ML, Kam LC, Hone JC. High throughput mechanobiology screening platform using micro- and nano-topography. Nano Letters. PMID 26990380 DOI: 10.1021/Acs.Nanolett.5B04364  0.406
2016 Dustin ML. Cancer immunotherapy: Killers on sterols. Nature. 531: 583-4. PMID 26982727 DOI: 10.1038/Nature17310  0.465
2016 Cai H, Wolfenson H, Depoil D, Dustin ML, Sheetz MP, Wind SJ. Molecular Occupancy of Nanodot Arrays. Acs Nano. PMID 26966946 DOI: 10.1021/Acsnano.5B07425  0.321
2016 Lin J, Yang L, Silva HM, Trzeciak A, Choi Y, Schwab SR, Dustin ML, Lafaille JJ. Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus. Nature Communications. 7: 10562. PMID 26923114 DOI: 10.1038/Ncomms10562  0.46
2016 Dustin ML, Davis SJ. Phagocytes Get Close to Their Enemies. Developmental Cell. 36: 131-2. PMID 26812012 DOI: 10.1016/J.Devcel.2016.01.004  0.556
2016 Depoil D, Dustin ML. Agile CD22 nanoclusters run rings around fenced BCR. The Embo Journal. 35: 237-8. PMID 26746852 DOI: 10.15252/Embj.201593745  0.397
2016 Jang J, Hajdu CH, Miller G, Dustin ML, Bar-Sagi D. Abstract A100: Crosstalk between regulatory T cells and tumor-associated dendritic cells controls antitumor immunity in pancreatic cancer Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A100  0.515
2016 Dustin M. Regulatory T Cell Immunological Synapse In Rheumatoid Arthritis Rheumatology. 55: 11-11. DOI: 10.1093/Rheumatology/Kew095  0.455
2015 Shaw TN, Stewart-Hutchinson PJ, Strangward P, Dandamudi DB, Coles JA, Villegas-Mendez A, Gallego-Delgado J, van Rooijen N, Zindy E, Rodriguez A, Brewer JM, Couper KN, Dustin ML. Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria. Plos Pathogens. 11: e1005210. PMID 26562533 DOI: 10.1371/Journal.Ppat.1005210  0.83
2015 Lee JH, Dustin ML, Kam LC. A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 26400012 DOI: 10.1039/C5Ib00215J  0.572
2015 Biswas KH, Hartman KL, Yu CH, Harrison OJ, Song H, Smith AW, Huang WY, Lin WC, Guo Z, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R, et al. E-cadherin junction formation involves an active kinetic nucleation process. Proceedings of the National Academy of Sciences of the United States of America. 112: 10932-7. PMID 26290581 DOI: 10.1073/Pnas.1513775112  0.346
2015 Tabdanov E, Gondarenko S, Kumari S, Liapis A, Dustin ML, Sheetz MP, Kam LC, Iskratsch T. Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 1272-84. PMID 26156536 DOI: 10.1039/C5Ib00032G  0.523
2015 Kumari S, Dustin ML. Immunology: Dendritic Cells Pull the T Cell's Strings. Current Biology : Cb. 25: R413-5. PMID 25989080 DOI: 10.1016/J.Cub.2015.03.040  0.485
2015 Dustin ML. T cells have a light touch. Biophysical Journal. 108: 2089-90. PMID 25954864 DOI: 10.1016/J.Bpj.2015.03.049  0.504
2015 Kuan EL, Ivanov S, Bridenbaugh EA, Victora G, Wang W, Childs EW, Platt AM, Jakubzick CV, Mason RJ, Gashev AA, Nussenzweig M, Swartz MA, Dustin ML, Zawieja DC, Randolph GJ. Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 5200-10. PMID 25917096 DOI: 10.4049/Jimmunol.1500221  0.638
2015 Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler FB, Kam LC, Carman CV, Burkhardt JK, Irvine DJ, Dustin ML. Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway. Elife. 4. PMID 25758716 DOI: 10.7554/Elife.04953  0.4
2015 Dustin M. Pointing B cells in the right direction. Journal of Experimental Medicine. 212: 3-4. PMID 25582314 DOI: 10.1084/Jem.2121Insight3  0.377
2015 Mayya V, Neiswanger W, Medina R, Wiggins CH, Dustin ML. Integrative analysis of T cell motility from multi-channel microscopy data using TIAM. Journal of Immunological Methods. 416: 84-93. PMID 25445324 DOI: 10.1016/J.Jim.2014.11.004  0.465
2015 Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler FB, Kam LC, Carman CV, Burkhardt JK, Irvine DJ, Dustin ML. Author response: Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway Elife. DOI: 10.7554/Elife.04953.034  0.389
2015 Blazar BR, O'Connor RS, Milone MC, Dustin ML, Riley JL, Vincent BG, Serody JS, Flynn RP, Paz K, Du J, Panoskaltsis-Mortari A, Jeffrey M, Ahmed R, Turka LAA, Freeman GJ, et al. Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease Blood. 126: SCI-8-SCI-8. DOI: 10.1182/Blood.V126.23.Sci-8.Sci-8  0.334
2015 McDonald-Hyman C, Thangavelu G, Muller J, Zhang G, Kumari S, Saha A, Koehn BH, Mitchell JS, Fife BT, Serody JS, Osborn MJ, Hippen KL, Kelekar A, Munn DH, Altman A, ... ... Dustin ML, et al. Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function Blood. 126: 849-849. DOI: 10.1182/Blood.V126.23.849.849  0.426
2015 Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Burrill JS, Guo L, Sacristan C, Furlan SN, ... ... Dustin ML, et al. Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality Blood. 126: 147-147. DOI: 10.1182/Blood.V126.23.147.147  0.435
2015 Cai H, Depoil D, Sheetz MP, Dustin ML, Wind SJ. Probing the Minimum Geometric Requirements for T-Cell Stimulation Biophysical Journal. 108: 631a-632a. DOI: 10.1016/J.Bpj.2014.11.3433  0.497
2014 Depoil D, Dustin ML. Force and affinity in ligand discrimination by the TCR. Trends in Immunology. 35: 597-603. PMID 25466309 DOI: 10.1016/J.It.2014.10.007  0.422
2014 Zanin-Zhorov A, Weiss JM, Nyuydzefe MS, Chen W, Scher JU, Mo R, Depoil D, Rao N, Liu B, Wei J, Lucas S, Koslow M, Roche M, Schueller O, Weiss S, ... ... Dustin ML, et al. Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 111: 16814-9. PMID 25385601 DOI: 10.1073/Pnas.1414189111  0.406
2014 Pollitt AY, Poulter NS, Gitz E, Navarro-Nuñez L, Wang YJ, Hughes CE, Thomas SG, Nieswandt B, Douglas MR, Owen DM, Jackson DG, Dustin ML, Watson SP. Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells. The Journal of Biological Chemistry. 289: 35695-710. PMID 25368330 DOI: 10.1074/Jbc.M114.584284  0.324
2014 Dustin ML. The immunological synapse. Cancer Immunology Research. 2: 1023-33. PMID 25367977 DOI: 10.1186/Ar559  0.516
2014 Thauland TJ, Koguchi Y, Dustin ML, Parker DC. CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation. Journal of Immunology (Baltimore, Md. : 1950). 193: 5894-903. PMID 25355918 DOI: 10.4049/Jimmunol.1401752  0.51
2014 Céspedes PF, Bueno SM, Ramírez BA, Gomez RS, Riquelme SA, Palavecino CE, Mackern-Oberti JP, Mora JE, Depoil D, Sacristán C, Cammer M, Creneguy A, Nguyen TH, Riedel CA, Dustin ML, et al. Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E3214-23. PMID 25056968 DOI: 10.1073/Pnas.1400760111  0.546
2014 Dustin ML. T-cells play the classics with a different spin. Molecular Biology of the Cell. 25: 1699-703. PMID 24874016 DOI: 10.1091/Mbc.E13-11-0636  0.519
2014 Dustin ML. What counts in the immunological synapse? Molecular Cell. 54: 255-62. PMID 24766889 DOI: 10.1016/J.Molcel.2014.04.001  0.512
2014 Dustin ML. How T cells lose their touch. Immunity. 40: 169-71. PMID 24560192 DOI: 10.1016/J.Immuni.2014.02.001  0.498
2014 Choudhuri K, Llodrá J, Roth EW, Tsai J, Gordo S, Wucherpfennig KW, Kam LC, Stokes DL, Dustin ML. Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse. Nature. 507: 118-23. PMID 24487619 DOI: 10.1038/Nature12951  0.565
2014 Dustin ML, Davis SJ. TCR signaling: the barrier within. Nature Immunology. 15: 136-7. PMID 24448571 DOI: 10.1038/Ni.2811  0.665
2014 Bashour KT, Tsai J, Shen K, Lee JH, Sun E, Milone MC, Dustin ML, Kam LC. Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility. Molecular and Cellular Biology. 34: 955-64. PMID 24379441 DOI: 10.1128/Mcb.00842-13  0.494
2014 Fooksman DR, Nussenzweig MC, Dustin ML. Myeloid cells limit production of antibody-secreting cells after immunization in the lymph node. Journal of Immunology (Baltimore, Md. : 1950). 192: 1004-12. PMID 24376270 DOI: 10.4049/Jimmunol.1300977  0.428
2014 Kumari S, Curado S, Mayya V, Dustin ML. T cell antigen receptor activation and actin cytoskeleton remodeling. Biochimica Et Biophysica Acta. 1838: 546-56. PMID 23680625 DOI: 10.1016/J.Bbamem.2013.05.004  0.564
2013 Cai H, Depoil D, Palma M, Sheetz MP, Dustin ML, Wind SJ. Bifunctional nanoarrays for probing the immune response at the single-molecule level. Journal of Vacuum Science and Technology. B, Nanotechnology & Microelectronics : Materials, Processing, Measurement, & Phenomena : Jvst B. 31: 6F902. PMID 24353927 DOI: 10.1116/1.4823764  0.501
2013 Williams CR, Dustin ML, Sauer JD. Inflammasome-mediated inhibition of Listeria monocytogenes-stimulated immunity is independent of myelomonocytic function. Plos One. 8: e83191. PMID 24349458 DOI: 10.1371/Journal.Pone.0083191  0.576
2013 Curado S, Kumari S, Dustin ML. "Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse. Current Topics in Membranes. 72: 313-46. PMID 24210434 DOI: 10.1016/B978-0-12-417027-8.00009-X  0.524
2013 Delcassian D, Depoil D, Rudnicka D, Liu M, Davis DM, Dustin ML, Dunlop IE. Nanoscale ligand spacing influences receptor triggering in T cells and NK cells. Nano Letters. 13: 5608-14. PMID 24125583 DOI: 10.1021/Nl403252X  0.545
2013 Deeg J, Axmann M, Matic J, Liapis A, Depoil D, Afrose J, Curado S, Dustin ML, Spatz JP. T cell activation is determined by the number of presented antigens. Nano Letters. 13: 5619-26. PMID 24117051 DOI: 10.1021/Nl403266T  0.517
2013 Waite JC, Vardhana S, Shaw PJ, Jang JE, McCarl CA, Cameron TO, Feske S, Dustin ML. Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo. European Journal of Immunology. 43: 3343-54. PMID 23939929 DOI: 10.1002/Eji.201243255  0.751
2013 Kam LC, Shen K, Dustin ML. Micro- and nanoscale engineering of cell signaling. Annual Review of Biomedical Engineering. 15: 305-26. PMID 23862677 DOI: 10.1146/Annurev-Bioeng-071811-150050  0.415
2013 Demaria S, Pilones KA, Formenti SC, Dustin ML. Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment. Oncoimmunology. 2: e23127. PMID 23802063 DOI: 10.4161/Onci.23127  0.449
2013 Dustin ML. Opening the frontier of the T cell surface: Schlossman and Goldstein. Journal of Immunology (Baltimore, Md. : 1950). 190: 5343-5. PMID 23687190 DOI: 10.4049/Jimmunol.1300951  0.404
2013 Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, ... ... Dustin ML, et al. The transcriptional landscape of αβ T cell differentiation. Nature Immunology. 14: 619-32. PMID 23644507 DOI: 10.1038/Ni.2590  0.418
2013 Cordoba SP, Choudhuri K, Zhang H, Bridge M, Basat AB, Dustin ML, van der Merwe PA. The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor. Blood. 121: 4295-302. PMID 23580664 DOI: 10.1182/Blood-2012-07-442251  0.517
2013 Zinselmeyer BH, Heydari S, Sacristán C, Nayak D, Cammer M, Herz J, Cheng X, Davis SJ, Dustin ML, McGavern DB. PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis. The Journal of Experimental Medicine. 210: 757-74. PMID 23530125 DOI: 10.1084/Jem.20121416  0.689
2013 Blair DA, Dustin ML. T cell priming goes through a new phase. Nature Immunology. 14: 311-2. PMID 23507636 DOI: 10.1038/Ni.2575  0.553
2013 Demaria S, Dustin ML. Role of the crosstalk between CTLA-4 and NKG2D in the development of anti-CTLA-4 treatment strategies. Immunotherapy. 5: 109-12. PMID 23413900 DOI: 10.2217/Imt.12.160  0.378
2013 Best JA, Blair DA, Knell J, Yang E, Mayya V, Doedens A, Dustin ML, Goldrath AW. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nature Immunology. 14: 404-12. PMID 23396170 DOI: 10.1038/Ni.2536  0.49
2013 Batista FD, Dustin ML. Cell:cell interactions in the immune system. Immunological Reviews. 251: 7-12. PMID 23278736 DOI: 10.1111/Imr.12025  0.519
2013 Liese J, Rooijakkers SH, van Strijp JA, Novick RP, Dustin ML. Intravital two-photon microscopy of host-pathogen interactions in a mouse model of Staphylococcus aureus skin abscess formation. Cellular Microbiology. 15: 891-909. PMID 23217115 DOI: 10.1111/Cmi.12085  0.314
2013 Dustin ML. T Cell Receptor-Associated Actin Patches Generated by Wiskott-Aldrich Syndrom Protein Biophysical Journal. 104: 8a. DOI: 10.1016/J.Bpj.2012.11.069  0.471
2012 Dustin ML. T cell receptors adapt by spacing out. Biophysical Journal. 103: 1813. PMID 23199905 DOI: 10.1016/J.Bpj.2012.09.012  0.524
2012 Weiss JM, Bilate AM, Gobert M, Ding Y, Curotto de Lafaille MA, Parkhurst CN, Xiong H, Dolpady J, Frey AB, Ruocco MG, Yang Y, Floess S, Huehn J, Oh S, Li MO, ... ... Dustin ML, et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. The Journal of Experimental Medicine. 209: 1723-42, S1. PMID 22966001 DOI: 10.1084/Jem.20120914  0.498
2012 Ruocco MG, Pilones KA, Kawashima N, Cammer M, Huang J, Babb JS, Liu M, Formenti SC, Dustin ML, Demaria S. Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects. The Journal of Clinical Investigation. 122: 3718-30. PMID 22945631 DOI: 10.1172/Jci61931  0.43
2012 Kumari S, Vardhana S, Cammer M, Curado S, Santos L, Sheetz MP, Dustin ML. T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse. Frontiers in Immunology. 3: 230. PMID 22912631 DOI: 10.3389/Fimmu.2012.00230  0.771
2012 Christie DA, Kirchhof MG, Vardhana S, Dustin ML, Madrenas J. Mitochondrial and plasma membrane pools of stomatin-like protein 2 coalesce at the immunological synapse during T cell activation. Plos One. 7: e37144. PMID 22623988 DOI: 10.1371/Journal.Pone.0037144  0.419
2012 Mazzon C, Anselmo A, Soldani C, Cibella J, Ploia C, Moalli F, Burden SJ, Dustin ML, Sarukhan A, Viola A. Agrin is required for survival and function of monocytic cells. Blood. 119: 5502-11. PMID 22517892 DOI: 10.1182/Blood-2011-09-382812  0.444
2012 Dustin ML. Signaling at neuro/immune synapses. The Journal of Clinical Investigation. 122: 1149-55. PMID 22466656 DOI: 10.1172/Jci58705  0.307
2012 Xu C, Shen Y, Littman DR, Dustin ML, Velázquez P. Visualization of mucosal homeostasis via single- and multiphoton intravital fluorescence microscopy. Journal of Leukocyte Biology. 92: 413-9. PMID 22457365 DOI: 10.1189/Jlb.0711344  0.45
2012 Prins KC, Vasiliver-Shamis G, Cammer M, Depoil D, Dustin ML, Hioe CE. Imaging of HIV-1 envelope-induced virological synapse and signaling on synthetic lipid bilayers. Journal of Visualized Experiments : Jove. PMID 22433250 DOI: 10.3791/3757  0.469
2012 Dustin ML, Groves JT. Receptor signaling clusters in the immune synapse. Annual Review of Biophysics. 41: 543-56. PMID 22404679 DOI: 10.1146/Annurev-Biophys-042910-155238  0.381
2012 Judokusumo E, Tabdanov E, Kumari S, Dustin ML, Kam LC. Mechanosensing in T lymphocyte activation. Biophysical Journal. 102: L5-7. PMID 22339876 DOI: 10.1016/J.Bpj.2011.12.011  0.557
2012 Schubert DA, Gordo S, Sabatino JJ, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW. Self-reactive human CD4 T cell clones form unusual immunological synapses. The Journal of Experimental Medicine. 209: 335-52. PMID 22312112 DOI: 10.1084/Jem.20111485  0.513
2012 Zanin-Zhorov A, Lin J, Scher J, Kumari S, Blair D, Hippen KL, Blazar BR, Abramson SB, Lafaille JJ, Dustin ML. Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function. Proceedings of the National Academy of Sciences of the United States of America. 109: 1625-30. PMID 22307621 DOI: 10.1073/Pnas.1110120109  0.562
2012 Dustin ML, Meyer-Hermann M. Immunology. Antigen feast or famine. Science (New York, N.Y.). 335: 408-9. PMID 22282794 DOI: 10.1126/Science.1218165  0.354
2012 Gottschalk RA, Hathorn MM, Beuneu H, Corse E, Dustin ML, Altan-Bonnet G, Allison JP. Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses. Proceedings of the National Academy of Sciences of the United States of America. 109: 881-6. PMID 22223661 DOI: 10.1073/Pnas.1119763109  0.504
2012 Springer TA, Dustin ML. Integrin inside-out signaling and the immunological synapse. Current Opinion in Cell Biology. 24: 107-15. PMID 22129583 DOI: 10.1016/J.Ceb.2011.10.004  0.504
2012 Park J, Fooksman DR, Mazumder A, Dustin ML. Multiple Myeloma Cells Adhere to Netrin-1 Via Heparin-Sulphate Moieties Blood. 120: 3952-3952. DOI: 10.1182/Blood.V120.21.3952.3952  0.43
2011 Dustin ML. Visualization of Cell-Cell Interaction Contacts: Synapses and Kinapses. Self/Nonself. 2: 85-97. PMID 22299060 DOI: 10.4161/self.2.2.17931  0.47
2011 Dustin ML, Depoil D. New insights into the T cell synapse from single molecule techniques. Nature Reviews. Immunology. 11: 672-84. PMID 21904389 DOI: 10.1038/Nri3066  0.561
2011 Hioe CE, Tuen M, Vasiliver-Shamis G, Alvarez Y, Prins KC, Banerjee S, Nádas A, Cho MW, Dustin ML, Kachlany SC. HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA). Plos One. 6: e23202. PMID 21850260 DOI: 10.1097/01.Qai.0000413802.72027.88  0.411
2011 Burroughs NJ, Köhler K, Miloserdov V, Dustin ML, van der Merwe PA, Davis DM. Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses. Plos Computational Biology. 7: e1002076. PMID 21829338 DOI: 10.1371/Journal.Pcbi.1002076  0.427
2011 Anandasabapathy N, Victora GD, Meredith M, Feder R, Dong B, Kluger C, Yao K, Dustin ML, Nussenzweig MC, Steinman RM, Liu K. Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. The Journal of Experimental Medicine. 208: 1695-705. PMID 21788405 DOI: 10.1084/Jem.20102657  0.659
2011 Zanin-Zhorov A, Dustin ML, Blazar BR. PKC-θ function at the immunological synapse: prospects for therapeutic targeting. Trends in Immunology. 32: 358-63. PMID 21733754 DOI: 10.1016/J.It.2011.04.007  0.527
2011 Mazzon C, Anselmo A, Cibella J, Soldani C, Destro A, Kim N, Roncalli M, Burden SJ, Dustin ML, Sarukhan A, Viola A. The critical role of agrin in the hematopoietic stem cell niche. Blood. 118: 2733-42. PMID 21653324 DOI: 10.1182/Blood-2011-01-331272  0.391
2011 Gutenkunst RN, Coombs D, Starr T, Dustin ML, Goldstein B. A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies. Plos One. 6: e19701. PMID 21629715 DOI: 10.1371/Journal.Pone.0019701  0.462
2011 Manz BN, Jackson BL, Petit RS, Dustin ML, Groves J. T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters. Proceedings of the National Academy of Sciences of the United States of America. 108: 9089-94. PMID 21576490 DOI: 10.1073/Pnas.1018771108  0.497
2011 Schwickert TA, Victora GD, Fooksman DR, Kamphorst AO, Mugnier MR, Gitlin AD, Dustin ML, Nussenzweig MC. A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. The Journal of Experimental Medicine. 208: 1243-52. PMID 21576382 DOI: 10.1084/Jem.20102477  0.719
2011 Rothlein R, Dustin ML, Marlin SD, Springer TA. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 1986. 137: 1270-1274. Journal of Immunology (Baltimore, Md. : 1950). 186: 5034-8. PMID 21505215  0.387
2011 Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254. Journal of Immunology (Baltimore, Md. : 1950). 186: 5024-33. PMID 21505214  0.35
2011 Kang SS, Herz J, Kim JV, Nayak D, Stewart-Hutchinson P, Dustin ML, McGavern DB. Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection. The Journal of Experimental Medicine. 208: 747-59. PMID 21464219 DOI: 10.1084/Jem.20101295  0.791
2011 Waite JC, Leiner I, Lauer P, Rae CS, Barbet G, Zheng H, Portnoy DA, Pamer EG, Dustin ML. Dynamic imaging of the effector immune response to listeria infection in vivo. Plos Pathogens. 7: e1001326. PMID 21455492 DOI: 10.1371/Journal.Ppat.1001326  0.771
2011 Milstein O, Hagin D, Lask A, Reich-Zeliger S, Shezen E, Ophir E, Eidelstein Y, Afik R, Antebi YE, Dustin ML, Reisner Y. CTLs respond with activation and granule secretion when serving as targets for T-cell recognition. Blood. 117: 1042-52. PMID 21045195 DOI: 10.1182/Blood-2010-05-283770  0.577
2011 Formenti S, Encouse G, Adams S, Pilones K, Ruocco MG, Dustin M, Demaria S. 35 INVITED Role of T-Lymphocytes for Tumour Response to Radiotherapy European Journal of Cancer. 47. DOI: 10.1016/S0959-8049(11)70250-7  0.394
2010 Victora GD, Schwickert TA, Fooksman DR, Kamphorst AO, Meyer-Hermann M, Dustin ML, Nussenzweig MC. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell. 143: 592-605. PMID 21074050 DOI: 10.1016/J.Cell.2010.10.032  0.689
2010 Choudhuri K, Dustin ML. Signaling microdomains in T cells. Febs Letters. 584: 4823-31. PMID 20965175 DOI: 10.1016/J.Febslet.2010.10.015  0.467
2010 Vasiliver-Shamis G, Dustin ML, Hioe CE. HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse. Viruses. 2: 1239-60. PMID 20890395 DOI: 10.3390/V2051239  0.448
2010 Dustin ML, Chakraborty AK, Shaw AS. Understanding the structure and function of the immunological synapse. Cold Spring Harbor Perspectives in Biology. 2: a002311. PMID 20843980 DOI: 10.1101/Cshperspect.A002311  0.347
2010 Fooksman DR, Schwickert TA, Victora GD, Dustin ML, Nussenzweig MC, Skokos D. Development and migration of plasma cells in the mouse lymph node. Immunity. 33: 118-27. PMID 20619695 DOI: 10.1016/J.Immuni.2010.06.015  0.621
2010 Owen DM, Oddos S, Kumar S, Davis DM, Neil MA, French PM, Dustin ML, Magee AI, Cebecauer M. High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells. Molecular Membrane Biology. 27: 178-89. PMID 20540668 DOI: 10.3109/09687688.2010.495353  0.391
2010 Dustin ML, Long EO. Cytotoxic immunological synapses. Immunological Reviews. 235: 24-34. PMID 20536553 DOI: 10.1111/J.0105-2896.2010.00904.X  0.499
2010 Fooksman DR, Dustin ML. Affinity measured by microcluster. The Journal of Experimental Medicine. 207: 907-9. PMID 20439542 DOI: 10.1084/Jem.20100780  0.457
2010 Shi C, Velázquez P, Hohl TM, Leiner I, Dustin ML, Pamer EG. Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression. Journal of Immunology (Baltimore, Md. : 1950). 184: 6266-74. PMID 20435926 DOI: 10.4049/Jimmunol.0904160  0.329
2010 Vardhana S, Choudhuri K, Varma R, Dustin ML. Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster. Immunity. 32: 531-40. PMID 20399684 DOI: 10.1016/J.Immuni.2010.04.005  0.759
2010 Zanin-Zhorov A, Ding Y, Kumari S, Attur M, Hippen KL, Brown M, Blazar BR, Abramson SB, Lafaille JJ, Dustin ML. Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science (New York, N.Y.). 328: 372-6. PMID 20339032 DOI: 10.1126/Science.1186068  0.427
2010 Fooksman DR, Vardhana S, Vasiliver-Shamis G, Liese J, Blair DA, Waite J, Sacristán C, Victora GD, Zanin-Zhorov A, Dustin ML. Functional anatomy of T cell activation and synapse formation. Annual Review of Immunology. 28: 79-105. PMID 19968559 DOI: 10.1146/Annurev-Immunol-030409-101308  0.847
2010 Dustin ML. Insights into function of the immunological synapse from studies with supported planar bilayers. Current Topics in Microbiology and Immunology. 340: 1-24. PMID 19960306 DOI: 10.1007/978-3-642-03858-7_1  0.48
2010 Schubert D, Gordo S, Vardhana S, Pyrdol J, Seth N, Raddassi K, Hafler D, Dustin M, Wucherpfennig K. Altered Synapse Formation by Self-reactive T Cells from MS Patients Clinical Immunology. 135: S75-S76. DOI: 10.1016/J.Clim.2010.03.227  0.39
2010 Gordo S, Schubert D, Vardhana S, Seth N, Pyrdol J, Raddassi K, Hafler D, Dustin M, Wucherpfennig K. Efficient Activation of Self-reactive T Cells from MS Patients with Altered Synapse Formation Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.031  0.395
2010 Tsai J, Shen K, Dustin ML, Milone M, Kam LC. Microscale Colocalization of CD3 and CD28 is Required for Activation of Human CD4+ T Cells Biophysical Journal. 98: 406a. DOI: 10.1016/J.Bpj.2009.12.2186  0.515
2010 Shen K, Dustin ML, Kam LC. Dynamic Force Generation within the Immune Synapse Biophysical Journal. 98: 367a. DOI: 10.1016/J.Bpj.2009.12.1978  0.511
2010 Mayya V, Dustin ML. Actin cytoskeleton and the dynamics of immunological synapse Actin-Based Motility: Cellular, Molecular and Physical Aspects. 103-124. DOI: 10.1007/978-90-481-9301-1_5  0.465
2010 Dunlop IE, Dustin ML, Spatz JP. The micro- and nanoscale architecture of the immunological synapse Nanotechnology. 323-343. DOI: 10.1002/9783527628155.Nanotech059  0.541
2010 Shen K, Milone MC, Dustin ML, Kam LC. Nanoengineering of immune cell function Materials Research Society Symposium Proceedings. 1209: 141-150.  0.446
2009 Shen K, Milone MC, Dustin ML, Kam LC. Nanoengineering of Immune Cell Function. Materials Research Society Symposia Proceedings. Materials Research Society. 1209. PMID 21562611 DOI: 10.1557/Proc-1209-Yy03-01  0.542
2009 Dustin ML. Modular design of immunological synapses and kinapses. Cold Spring Harbor Perspectives in Biology. 1: a002873. PMID 20066081 DOI: 10.1101/Cshperspect.A002873  0.532
2009 Beal AM, Anikeeva N, Varma R, Cameron TO, Vasiliver-Shamis G, Norris PJ, Dustin ML, Sykulev Y. Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain. Immunity. 31: 632-42. PMID 19833088 DOI: 10.1016/J.Immuni.2009.09.004  0.423
2009 Vasiliver-Shamis G, Cho MW, Hioe CE, Dustin ML. Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse. Journal of Virology. 83: 11341-55. PMID 19710135 DOI: 10.1128/Jvi.01440-09  0.495
2009 Chen HY, Fermin A, Vardhana S, Weng IC, Lo KF, Chang EY, Maverakis E, Yang RY, Hsu DK, Dustin ML, Liu FT. Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proceedings of the National Academy of Sciences of the United States of America. 106: 14496-501. PMID 19706535 DOI: 10.1073/Pnas.0903497106  0.593
2009 Darrasse-Jèze G, Deroubaix S, Mouquet H, Victora GD, Eisenreich T, Yao KH, Masilamani RF, Dustin ML, Rudensky A, Liu K, Nussenzweig MC. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. The Journal of Experimental Medicine. 206: 1853-62. PMID 19667061 DOI: 10.1084/Jem.20090746  0.747
2009 Liu D, Bryceson YT, Meckel T, Vasiliver-Shamis G, Dustin ML, Long EO. Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses. Immunity. 31: 99-109. PMID 19592272 DOI: 10.1016/J.Immuni.2009.05.009  0.424
2009 Srivastava S, Di L, Zhdanova O, Li Z, Vardhana S, Wan Q, Yan Y, Varma R, Backer J, Wulff H, Dustin ML, Skolnik EY. The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells. Molecular Biology of the Cell. 20: 3783-91. PMID 19587117 DOI: 10.1091/Mbc.E09-05-0390  0.755
2009 Buonamici S, Trimarchi T, Ruocco MG, Reavie L, Cathelin S, Mar BG, Klinakis A, Lukyanov Y, Tseng JC, Sen F, Gehrie E, Li M, Newcomb E, Zavadil J, Meruelo D, ... ... Dustin ML, et al. CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature. 459: 1000-4. PMID 19536265 DOI: 10.1038/Nature08020  0.49
2009 Dustin ML. Multiscale analysis of T cell activation: correlating in vitro and in vivo analysis of the immunological synapse. Current Topics in Microbiology and Immunology. 334: 47-70. PMID 19521681 DOI: 10.1007/978-3-540-93864-4_3  0.544
2009 Dustin ML. Supported bilayers at the vanguard of immune cell activation studies. Journal of Structural Biology. 168: 152-60. PMID 19500675 DOI: 10.1016/J.Jsb.2009.05.007  0.468
2009 Kaizuka Y, Douglass AD, Vardhana S, Dustin ML, Vale RD. The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells. The Journal of Cell Biology. 185: 521-34. PMID 19398758 DOI: 10.1083/Jcb.200809136  0.57
2009 Dustin ML. The cellular context of T cell signaling. Immunity. 30: 482-92. PMID 19371714 DOI: 10.1016/J.Immuni.2009.03.010  0.558
2009 Dustin ML. Visualizing immune system complexity. Science Signaling. 2: mr4. PMID 19366990 DOI: 10.1126/Scisignal.266Mr4  0.335
2009 Ilani T, Vasiliver-Shamis G, Vardhana S, Bretscher A, Dustin ML. T cell antigen receptor signaling and immunological synapse stability require myosin IIA Nature Immunology. 10: 531-539. PMID 19349987 DOI: 10.1038/Ni.1723  0.538
2009 Mor A, Wynne JP, Ahearn IM, Dustin ML, Du G, Philips MR. Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane. Molecular and Cellular Biology. 29: 3297-306. PMID 19332557 DOI: 10.1128/Mcb.00366-09  0.434
2009 Dehan E, Bassermann F, Guardavaccaro D, Vasiliver-Shamis G, Cohen M, Lowes KN, Dustin M, Huang DC, Taunton J, Pagano M. betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. Molecular Cell. 33: 109-16. PMID 19150432 DOI: 10.1016/J.Molcel.2008.12.020  0.311
2009 Kim JV, Kang SS, Dustin ML, McGavern DB. Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis. Nature. 457: 191-5. PMID 19011611 DOI: 10.1038/Nature07591  0.503
2009 Vasiliver-Shamis G, Cho MW, Dustin ML, Hioe CE. P07-03. HIV gp120 interaction with CD4+ T cells induces local intracellular signaling and creates an F-actin depleted zone in the virological synapse Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P101  0.452
2009 Vasiliver-Shamis G, Cho M, Dustin ML, Hioe CE. 119 HIV-1 envelope gp120 induces a stop signal and virological synapse formation in non-infected CD4+ T cells Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351076.74461.96  0.444
2009 Manz BN, Jackson BL, Petit RS, Dustin ML, Groves JT. Dissecting T cell receptor nanocluster signaling Biophysical Journal. 96: 680a-681a. DOI: 10.1016/J.Bpj.2008.12.3596  0.537
2008 Vardhana S, Dustin M. Supported Planar Bilayers for the Formation of Study of Immunological Synapses and Kinapse. Journal of Visualized Experiments. PMID 19066534 DOI: 10.3791/947  0.741
2008 Dustin ML. Visualization of cell-cell interaction contacts-synapses and kinapses Advances in Experimental Medicine and Biology. 640: 164-182. PMID 19065791 DOI: 10.1007/978-0-387-09789-3_13  0.558
2008 Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T. Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation. Immunity. 29: 589-601. PMID 18848472 DOI: 10.1016/J.Immuni.2008.08.011  0.587
2008 Kim N, Stiegler AL, Cameron TO, Hallock PT, Gomez AM, Huang JH, Hubbard SR, Dustin ML, Burden SJ. Lrp4 is a receptor for Agrin and forms a complex with MuSK. Cell. 135: 334-42. PMID 18848351 DOI: 10.1016/J.Cell.2008.10.002  0.313
2008 Milstein O, Tseng SY, Starr T, Llodra J, Nans A, Liu M, Wild MK, van der Merwe PA, Stokes DL, Reisner Y, Dustin ML. Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. The Journal of Biological Chemistry. 283: 34414-22. PMID 18826951 DOI: 10.1074/Jbc.M804756200  0.406
2008 Tseng SY, Waite JC, Liu M, Vardhana S, Dustin ML. T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta. Journal of Immunology (Baltimore, Md. : 1950). 181: 4852-63. PMID 18802089 DOI: 10.4049/Jimmunol.181.7.4852  0.838
2008 Beal AM, Anikeeva N, Varma R, Cameron TO, Norris PJ, Dustin ML, Sykulev Y. Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL. Journal of Immunology (Baltimore, Md. : 1950). 181: 4815-24. PMID 18802085 DOI: 10.4049/Jimmunol.181.7.4815  0.463
2008 Matsumura S, Wang B, Kawashima N, Braunstein S, Badura M, Cameron TO, Babb JS, Schneider RJ, Formenti SC, Dustin ML, Demaria S. Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 3099-107. PMID 18713980 DOI: 10.4049/Jimmunol.181.5.3099  0.478
2008 Kirchhof MG, Chau LA, Lemke CD, Vardhana S, Darlington PJ, Márquez ME, Taylor R, Rizkalla K, Blanca I, Dustin ML, Madrenas J. Modulation of T cell activation by stomatin-like protein 2. Journal of Immunology (Baltimore, Md. : 1950). 181: 1927-36. PMID 18641330 DOI: 10.4049/Jimmunol.181.3.1927  0.546
2008 Vasiliver-Shamis G, Tuen M, Wu TW, Starr T, Cameron TO, Thomson R, Kaur G, Liu J, Visciano ML, Li H, Kumar R, Ansari R, Han DP, Cho MW, Dustin ML, et al. Human immunodeficiency virus type 1 envelope gp120 induces a stop signal and virological synapse formation in noninfected CD4+ T cells. Journal of Virology. 82: 9445-57. PMID 18632854 DOI: 10.1128/Jvi.00835-08  0.527
2008 Dustin ML. Hunter to gatherer and back: Immunological synapses and kinapses as variations on the theme of amoeboid locomotion Annual Review of Cell and Developmental Biology. 24: 577-596. PMID 18598213 DOI: 10.1146/Annurev.Cellbio.24.110707.175226  0.398
2008 Thauland TJ, Koguchi Y, Wetzel SA, Dustin ML, Parker DC. Th1 and Th2 cells form morphologically distinct immunological synapses. Journal of Immunology (Baltimore, Md. : 1950). 181: 393-9. PMID 18566405 DOI: 10.4049/Jimmunol.181.1.393  0.438
2008 Shen K, Thomas VK, Dustin ML, Kam LC. Micropatterning of costimulatory ligands enhances CD4+ T cell function. Proceedings of the National Academy of Sciences of the United States of America. 105: 7791-6. PMID 18505845 DOI: 10.1073/Pnas.0710295105  0.789
2008 Tolentino TP, Wu J, Zarnitsyna VI, Fang Y, Dustin ML, Zhu C. Measuring diffusion and binding kinetics by contact area FRAP. Biophysical Journal. 95: 920-30. PMID 18390627 DOI: 10.1529/Biophysj.107.114447  0.329
2008 Dustin ML. Synaptic Asymmetry to Go Cell. 132: 733-734. PMID 18329360 DOI: 10.1016/J.Cell.2008.02.016  0.499
2008 Dustin ML. T-cell activation through immunological synapses and kinapses Immunological Reviews. 221: 77-89. PMID 18275476 DOI: 10.1111/J.1600-065X.2008.00589.X  0.561
2008 Velázquez P, Cameron TO, Kinjo Y, Nagarajan N, Kronenberg M, Dustin ML. Cutting edge: activation by innate cytokines or microbial antigens can cause arrest of natural killer T cell patrolling of liver sinusoids. Journal of Immunology (Baltimore, Md. : 1950). 180: 2024-8. PMID 18250405 DOI: 10.4049/Jimmunol.180.4.2024  0.406
2008 DeMond AL, Mossman KD, Starr T, Dustin ML, Groves JT. T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation. Biophysical Journal. 94: 3286-92. PMID 18199675 DOI: 10.1529/Biophysj.107.119099  0.453
2008 Kim JV, Tadokoro CE, Shen S, Jiang N, Lafaille JJ, Dustin ML. CXCR6 is required for T cell recruitment into injured gray matter in EAE The Faseb Journal. 22: 424-424. DOI: 10.1096/Fasebj.22.2_Supplement.424  0.483
2007 Dustin ML, Starr T, Varma R, Thomas VK. Supported planar bilayers for study of the immunological synapse. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 18.13. PMID 18432988 DOI: 10.1002/0471142735.Im1813S76  0.747
2007 Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD. Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 20296-301. PMID 18077330 DOI: 10.1073/Pnas.0710258105  0.523
2007 Velázquez P, Waite JC, Dustin ML. Dynamics of host defense: the view at the front lines. Nature Immunology. 8: 1153-7. PMID 17952039 DOI: 10.1038/Ni1520  0.67
2007 Dustin ML. Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses Current Opinion in Cell Biology. 19: 529-533. PMID 17923403 DOI: 10.1016/J.Ceb.2007.08.003  0.454
2007 Dustin ML, Starr T, Coombs D, Majeau GR, Meier W, Hochman PS, Douglass A, Vale R, Goldstein B, Whitty A. Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion. The Journal of Biological Chemistry. 282: 34748-57. PMID 17911103 DOI: 10.1074/Jbc.M705616200  0.497
2007 Skokos D, Shakhar G, Varma R, Waite JC, Cameron TO, Lindquist RL, Schwickert T, Nussenzweig MC, Dustin ML. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nature Immunology. 8: 835-44. PMID 17632517 DOI: 10.1038/Ni1490  0.793
2007 Mor A, Dustin ML, Philips MR. Small GTPases and LFA-1 reciprocally modulate adhesion and signaling. Immunological Reviews. 218: 114-25. PMID 17624948 DOI: 10.1111/J.1600-065X.2007.00538.X  0.471
2007 Huang JH, Cárdenas-Navia LI, Caldwell CC, Plumb TJ, Radu CG, Rocha PN, Wilder T, Bromberg JS, Cronstein BN, Sitkovsky M, Dewhirst MW, Dustin ML. Requirements for T lymphocyte migration in explanted lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 178: 7747-55. PMID 17548612 DOI: 10.4049/Jimmunol.178.12.7747  0.483
2007 Sims TN, Soos TJ, Xenias HS, Dubin-Thaler B, Hofman JM, Waite JC, Cameron TO, Thomas VK, Varma R, Wiggins CH, Sheetz MP, Littman DR, Dustin ML. Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse. Cell. 129: 773-85. PMID 17512410 DOI: 10.1016/J.Cell.2007.03.037  0.839
2007 Mor A, Campi G, Du G, Zheng Y, Foster DA, Dustin ML, Philips MR. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nature Cell Biology. 9: 713-9. PMID 17486117 DOI: 10.1038/Ncb1592  0.66
2007 Schwickert TA, Lindquist RL, Shakhar G, Livshits G, Skokos D, Kosco-Vilbois MH, Dustin ML, Nussenzweig MC. In vivo imaging of germinal centres reveals a dynamic open structure. Nature. 446: 83-7. PMID 17268470 DOI: 10.1038/Nature05573  0.433
2007 Alon R, Dustin ML. Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity. 26: 17-27. PMID 17241958 DOI: 10.1016/J.Immuni.2007.01.002  0.395
2007 Zhu DM, Dustin ML, Cairo CW, Golan DE. Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules. Biophysical Journal. 92: 1022-34. PMID 17085486 DOI: 10.1529/Biophysj.106.089649  0.448
2007 Kirchhof MG, Chau LA, Lemke CD, Vardhana S, Darlington PJ, Marquez ME, Taylor R, Rizkalla K, Blaca I, Dustin ML, Madrenas J. Stomatin-like Protein 2 Links Mitochondria to T-Cell Receptor Signalosomes at the Immunological Synapse and Enhances T-Cell Activation Nature Precedings. 2: 1-1. DOI: 10.1038/Npre.2007.1068.1  0.534
2007 Skokos D, Shakhar G, Varma R, Waite JC, Cameron TO, Lindquist RL, Schwickert T, Nussenzweig MC, Dustin ML. Erratum: Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes Nature Immunology. 8: 1266-1266. DOI: 10.1038/Ni1107-1266A  0.746
2006 Zhu DM, Dustin ML, Cairo CW, Thatte HS, Golan DE. Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion. Acs Chemical Biology. 1: 649-58. PMID 17168569 DOI: 10.1021/Cb6002515  0.511
2006 DeMond AL, Starr T, Dustin ML, Groves JT. Control of antigen presentation with a photoreleasable agonist peptide. Journal of the American Chemical Society. 128: 15354-5. PMID 17131984 DOI: 10.1021/Ja065304L  0.503
2006 Anikeeva N, Lebedeva T, Clapp AR, Goldman ER, Dustin ML, Mattoussi H, Sykulev Y. Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response. Proceedings of the National Academy of Sciences of the United States of America. 103: 16846-51. PMID 17077145 DOI: 10.1073/Pnas.0607771103  0.495
2006 Dustin ML. Impact of the immunological synapse on T cell signaling Results and Problems in Cell Differentiation. 43: 175-198. PMID 17068972 DOI: 10.1007/400_019  0.566
2006 Döbereiner HG, Dubin-Thaler BJ, Hofman JM, Xenias HS, Sims TN, Giannone G, Dustin ML, Wiggins CH, Sheetz MP. Lateral membrane waves constitute a universal dynamic pattern of motile cells. Physical Review Letters. 97: 038102. PMID 16907546 DOI: 10.1103/Physrevlett.97.038102  0.385
2006 Dustin ML. When F-actin becomes too much of a good thing Science. 313: 767-768. PMID 16902113 DOI: 10.1126/Science.1131714  0.324
2006 Varma R, Campi G, Yokosuka T, Saito T, Dustin ML. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity. 25: 117-27. PMID 16860761 DOI: 10.1016/J.Immuni.2006.04.010  0.69
2006 Germain RN, Miller MJ, Dustin ML, Nussenzweig MC. Dynamic imaging of the immune system: Progress, pitfalls and promise Nature Reviews Immunology. 6: 497-507. PMID 16799470 DOI: 10.1038/Nri1884  0.384
2006 Dustin ML, Tseng SY, Varma R, Campi G. T cell-dendritic cell immunological synapses. Current Opinion in Immunology. 18: 512-6. PMID 16777399 DOI: 10.1016/J.Coi.2006.05.017  0.737
2006 Dustin ML, Zhu C. T cells like a firm molecular handshake Proceedings of the National Academy of Sciences of the United States of America. 103: 4335-4336. PMID 16537367 DOI: 10.1073/Pnas.0600899103  0.483
2006 Tadokoro CE, Shakhar G, Shen S, Ding Y, Lino AC, Maraver A, Lafaille JJ, Dustin ML. Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. The Journal of Experimental Medicine. 203: 505-11. PMID 16533880 DOI: 10.1084/Jem.20050783  0.549
2006 Tadokoro CE, Shakhar G, Shen S, Ding Y, Lino AC, Maraver A, Lafaille JJ, Dustin ML. Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo Journal of Cell Biology. 172: i17-i17. DOI: 10.1083/JCB1727OIA17  0.479
2006 Lebedeva T, Dustin ML, Sykulev Y. Target Cell Contributions to Cytotoxic T Cell Sensitivity Antigen Presenting Cells: From Mechanisms to Drug Development. 199-220. DOI: 10.1002/3527607021.ch7  0.384
2005 Tseng SY, Liu M, Dustin ML. CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse. Journal of Immunology (Baltimore, Md. : 1950). 175: 7829-36. PMID 16339518 DOI: 10.4049/Jimmunol.175.12.7829  0.506
2005 Mossman KD, Campi G, Groves JT, Dustin ML. Altered TCR signaling from geometrically repatterned immunological synapses. Science (New York, N.Y.). 310: 1191-3. PMID 16293763 DOI: 10.1126/Science.1119238  0.676
2005 Yokosuka T, Sakata-Sogawa K, Kobayashi W, Hiroshima M, Hashimoto-Tane A, Tokunaga M, Dustin ML, Saito T. Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nature Immunology. 6: 1253-62. PMID 16273097 DOI: 10.1038/Ni1272  0.509
2005 Dustin ML. A dynamic view of the immunological synapse Seminars in Immunology. 17: 400-410. PMID 16266811 DOI: 10.1016/J.Smim.2005.09.002  0.567
2005 Campi G, Varma R, Dustin ML. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. The Journal of Experimental Medicine. 202: 1031-6. PMID 16216891 DOI: 10.1084/Jem.20051182  0.705
2005 Shakhar G, Lindquist RL, Skokos D, Dudziak D, Huang JH, Nussenzweig MC, Dustin ML. Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo Nature Immunology. 6: 707-714. PMID 15924144 DOI: 10.1038/Ni1210  0.526
2005 Shao JY, Yu Y, Dustin ML. A model for CD2/CD58-mediated adhesion strengthening. Annals of Biomedical Engineering. 33: 483-93. PMID 15909654 DOI: 10.1007/S10439-005-2504-5  0.416
2005 Lebedeva T, Dustin ML, Sykulev Y. ICAM-1 co-stimulates target cells to facilitate antigen presentation Current Opinion in Immunology. 17: 251-258. PMID 15886114 DOI: 10.1016/J.Coi.2005.04.008  0.591
2005 Anikeeva N, Somersalo K, Sims TN, Thomas VK, Dustin ML, Sykulev Y. Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 102: 6437-42. PMID 15851656 DOI: 10.1073/Pnas.0502467102  0.824
2005 Geissmann F, Cameron TO, Sidobre S, Manlongat N, Kronenberg M, Briskin MJ, Dustin ML, Littman DR. Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids Plos Biology.. 3: e113. PMID 15799695 DOI: 10.1371/Journal.Pbio.0030113  0.457
2005 Dustin ML. Antibody catches T-cell receptor in the act Blood. 106: 396. DOI: 10.1182/Blood-2005-04-1695  0.496
2005 Heissmeyer V, Macián F, Varma R, Im SH, García-Cozar F, Horton HF, Byrne MC, Feske S, Venuprasad K, Gu H, Liu YC, Dustin ML, Rao A. A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling. Novartis Foundation Symposium. 267: 165-174. DOI: 10.1002/047002139X.Ch11  0.405
2004 Lindquist RL, Shakhar G, Dudziak D, Wardemann H, Eisenreich T, Dustin ML, Nussenzweig MC. Visualizing dendritic cell networks in vivo Nature Immunology. 5: 1243-1250. PMID 15543150 DOI: 10.1038/Ni1139  0.418
2004 Sims TN, Dustin ML. A polarizing situation. Nature Immunology. 5: 1012-3. PMID 15454929 DOI: 10.1038/Ni1004-1012  0.454
2004 Dustin ML. Stop and go traffic to tune T cell responses Immunity. 21: 305-314. PMID 15357942 DOI: 10.1016/J.Immuni.2004.08.016  0.486
2004 Sumen C, Dustin ML, Davis MM. T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation. The Journal of Cell Biology. 166: 579-90. PMID 15314068 DOI: 10.1083/Jcb.200404059  0.559
2004 Davis DM, Dustin ML. What is the importance of the immunological synapse? Trends in Immunology. 25: 323-327. PMID 15145322 DOI: 10.1016/J.It.2004.03.007  0.435
2004 Carrasco YR, Fleire SJ, Cameron T, Dustin ML, Batista FD. LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation Immunity. 20: 589-599. PMID 15142527 DOI: 10.1016/S1074-7613(04)00105-0  0.44
2004 Dustin M. A Supercode for Inflammation Immunity. 20: 361-362. PMID 15084264 DOI: 10.1016/S1074-7613(04)00083-4  0.39
2004 Dustin ML, Bivona TG, Philips MR. Membranes as messengers in T cell adhesion signaling. Nature Immunology. 5: 363-72. PMID 15052266 DOI: 10.1038/Ni1057  0.424
2004 Heissmeyer V, Macián F, Im SH, Varma R, Feske S, Venuprasad K, Gu H, Liu YC, Dustin ML, Rao A. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nature Immunology. 5: 255-65. PMID 14973438 DOI: 10.1038/Ni1047  0.481
2004 Somersalo K, Anikeeva N, Sims TN, Thomas VK, Strong RK, Spies T, Lebedeva T, Sykulev Y, Dustin ML. Cytotoxic T lymphocytes form an antigen-independent ring junction. The Journal of Clinical Investigation. 113: 49-57. PMID 14702108 DOI: 10.1172/Jci19337  0.826
2004 Dustin ML. New ways for lymphocytes to meet Blood. 104: 2618-2619. DOI: 10.1182/Blood-2004-08-3084  0.422
2003 Lee KH, Dinner AR, Tu C, Campi G, Raychaudhuri S, Varma R, Sims TN, Burack WR, Wu H, Wang J, Kanagawa O, Markiewicz M, Allen PM, Dustin ML, Chakraborty AK, et al. The immunological synapse balances T cell receptor signaling and degradation. Science (New York, N.Y.). 302: 1218-22. PMID 14512504 DOI: 10.1126/Science.1086507  0.751
2003 Groves JT, Dustin ML. Supported planar bilayers in studies on immune cell adhesion and communication. Journal of Immunological Methods. 278: 19-32. PMID 12957393 DOI: 10.1016/S0022-1759(03)00193-5  0.482
2003 Dustin ML. Coordination of T cell activation and migration through formation of the immunological synapse Annals of the New York Academy of Sciences. 987: 51-59. PMID 12727623 DOI: 10.1111/J.1749-6632.2003.Tb06032.X  0.566
2003 Dustin M. Viral spread through protoplasmic kiss Nature Cell Biology. 5: 271-272. PMID 12669071 DOI: 10.1038/Ncb0403-271  0.332
2002 Dustin ML. Regulation of T cell migration through formation of immunological synapses: The stop signal hypothesis Advances in Experimental Medicine and Biology. 512: 191-201. PMID 12405204 DOI: 10.1007/978-1-4615-0757-4_25  0.476
2002 Dustin ML, Colman DR. Neural and immunological synaptic relations. Science (New York, N.Y.). 298: 785-9. PMID 12399580 DOI: 10.1126/Science.1076386  0.398
2002 Lee SJ, Hori Y, Groves JT, Dustin ML, Chakraborty AK. The synapse assembly model. Trends in Immunology. 23: 500-2. PMID 12297422 DOI: 10.1016/S1471-4906(02)02325-6  0.313
2002 Lee SJ, Hori Y, Groves JT, Dustin ML, Chakraborty AK. Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation. Trends in Immunology. 23: 492-9. PMID 12297421 DOI: 10.1016/S1471-4906(02)02285-8  0.508
2002 Sims TN, Dustin ML. The immunological synapse: integrins take the stage. Immunological Reviews. 186: 100-17. PMID 12234366 DOI: 10.1034/J.1600-065X.2002.18610.X  0.523
2002 Tseng SY, Dustin ML. T-cell activation: a multidimensional signaling network. Current Opinion in Cell Biology. 14: 575-80. PMID 12231352 DOI: 10.1016/S0955-0674(02)00370-8  0.524
2002 Burack WR, Lee KH, Holdorf AD, Dustin ML, Shaw AS. Cutting edge: quantitative imaging of raft accumulation in the immunological synapse. Journal of Immunology (Baltimore, Md. : 1950). 169: 2837-41. PMID 12218094 DOI: 10.4049/Jimmunol.169.6.2837  0.338
2002 Dustin ML. Shmoos, rafts, and uropods - The many facets of cell polarity Cell. 110: 13-18. PMID 12150993 DOI: 10.1016/S0092-8674(02)00820-6  0.355
2002 Hailman E, Burack WR, Shaw AS, Dustin ML, Allen PM. Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. Immunity. 16: 839-48. PMID 12121665 DOI: 10.1016/S1074-7613(02)00326-6  0.477
2002 Dustin ML. The immunological synapse. Arthritis Research. S119-25. PMID 12110130 DOI: 10.1186/ar559  0.439
2002 Bromley SK, Dustin ML. Stimulation of naïve T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms Immunology. 106: 289-298. PMID 12100716 DOI: 10.1046/J.1365-2567.2002.01441.X  0.545
2002 Savage ND, Kimzey SL, Bromley SK, Johnson KG, Dustin ML, Green JM. Polar redistribution of the sialoglycoprotein CD43: implications for T cell function. Journal of Immunology (Baltimore, Md. : 1950). 168: 3740-6. PMID 11937524 DOI: 10.4049/Jimmunol.168.8.3740  0.565
2002 Antón IM, de la Fuente MA, Sims TN, Freeman S, Ramesh N, Hartwig JH, Dustin ML, Geha RS. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity. 16: 193-204. PMID 11869681 DOI: 10.1016/S1074-7613(02)00268-6  0.538
2002 Lee KH, Holdorf AD, Dustin ML, Chan AC, Allen PM, Shaw AS. T cell receptor signaling precedes immunological synapse formation. Science (New York, N.Y.). 295: 1539-42. PMID 11859198 DOI: 10.1126/Science.1067710  0.557
2002 Dustin ML. Membrane domains and the immunological synapse: Keeping T cells resting and ready Journal of Clinical Investigation. 109: 155-160. PMID 11805125 DOI: 10.1172/Jci14842  0.54
2002 Wülfing C, Sumen C, Sjaastad MD, Wu LC, Dustin ML, Davis MM. Costimulation and endogenous MHC ligands contribute to T cell recognition. Nature Immunology. 3: 42-7. PMID 11731799 DOI: 10.1038/Ni741  0.516
2002 Thomas VK, Wu J, Zhu C, Dustin ML. Dynamics of surface receptor interactions required for an immune response Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 345-346.  0.777
2001 Bromley SK, Iaboni A, Davis SJ, Whitty A, Green JM, Shaw AS, Weiss A, Dustin ML. The immunological synapse and CD28-CD80 interactions. Nature Immunology. 2: 1159-66. PMID 11713465 DOI: 10.1038/Ni737  0.69
2001 Dustin ML, Bromley SK, Davis MM, Zhu C. Identification of self through two-dimensional chemistry and synapses Annual Review of Cell and Developmental Biology. 17: 133-157. PMID 11687486 DOI: 10.1146/Annurev.Cellbio.17.1.133  0.342
2001 Dustin ML. Role of adhesion molecules in activation signaling in T lymphocytes Journal of Clinical Immunology. 21: 258-263. PMID 11506195 DOI: 10.1023/A:1010927208180  0.566
2001 Dustin ML, De Fougerolles AR. Reprograming T cells: The role of extracellular matrix in coordination of T cell activation and migration Current Opinion in Immunology. 13: 286-290. PMID 11406359 DOI: 10.1016/S0952-7915(00)00217-X  0.53
2001 Dustin ML, Dustin LB. The immunological relay race: B cells take antigen by synapse Nature Immunology. 2: 480-482. PMID 11376330 DOI: 10.1038/88666  0.486
2001 Dustin ML, Allen PM, Shaw AS. Environmental control of immunological synapse formation and duration. Trends in Immunology. 22: 192-4. PMID 11274923 DOI: 10.1016/S1471-4906(01)01872-5  0.498
2001 Bromley SK, Burack WR, Johnson KG, Somersalo K, Sims TN, Sumen C, Davis MM, Shaw AS, Allen PM, Dustin ML. The immunological synapse. Annual Review of Immunology. 19: 375-96. PMID 11244041 DOI: 10.1146/Annurev.Immunol.19.1.375  0.557
2000 Johnson KG, Bromley SK, Dustin ML, Thomas ML. A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 97: 10138-43. PMID 10963676 DOI: 10.1073/Pnas.97.18.10138  0.493
2000 Dustin ML, Cooper JA. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling Nature Immunology. 1: 23-29. PMID 10881170 DOI: 10.1038/76877  0.51
2000 Bromley SK, Peterson DA, Gunn MD, Dustin ML. Cutting edge: Hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation Journal of Immunology. 165: 15-19. PMID 10861029 DOI: 10.4049/Jimmunol.165.1.15  0.549
2000 Anton van der Merwe P, Davis SJ, Shaw AS, Dustin ML. Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition. Seminars in Immunology. 12: 5-21. PMID 10723794 DOI: 10.1006/Smim.2000.0203  0.667
2000 Mordue DG, Desai N, Dustin M, Sibley LD. Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring. The Journal of Experimental Medicine. 190: 1783-92. PMID 10601353 DOI: 10.1084/Jem.190.12.1783  0.377
1999 Davis MM, Wülfing C, Krummel MF, Savage PA, Xu J, Sumen C, Dustin ML, Chien YH. Visualizing T-cell recognition. Cold Spring Harbor Symposia On Quantitative Biology. 64: 243-51. PMID 11232292 DOI: 10.1101/Sqb.1999.64.243  0.42
1999 Shih NY, Li J, Karpitskii V, Nguyen A, Dustin ML, Kanagawa O, Miner JH, Shaw AS. Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science (New York, N.Y.). 286: 312-5. PMID 10514378 DOI: 10.1126/Science.286.5438.312  0.437
1999 Grakoui A, Bromley SK, Sumen C, Davis MM, Shaw AS, Allen PM, Dustin ML. The immunological synapse: a molecular machine controlling T cell activation. Science (New York, N.Y.). 285: 221-7. PMID 10398592 DOI: 10.1126/Science.285.5425.221  0.537
1999 Dustin ML, Shaw AS. Costimulation: building an immunological synapse. Science (New York, N.Y.). 283: 649-50. PMID 9988658 DOI: 10.1126/Science.283.5402.649  0.448
1998 Dustin ML. Making a little affinity go a long way: A topological view of LFA-1 regulation Cell Adhesion and Communication. 6: 255-262. PMID 9823476 DOI: 10.3109/15419069809004481  0.368
1998 Dustin ML, Olszowy MW, Holdorf AD, Li J, Bromley S, Desai N, Widder P, Rosenberger F, van der Merwe PA, Allen PM, Shaw AS. A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. Cell. 94: 667-77. PMID 9741631 DOI: 10.1016/S0092-8674(00)81608-6  0.509
1998 Dustin ML. Regulation of cell migration by stop signals Experimental Hematology. 26: 703.  0.403
1997 Dustin ML, Golan DE, Zhu DM, Miller JM, Meier W, Davies EA, van der Merwe PA. Low affinity interaction of human or rat T cell adhesion molecule CD2 with its ligand aligns adhering membranes to achieve high physiological affinity. The Journal of Biological Chemistry. 272: 30889-98. PMID 9388235 DOI: 10.1074/Jbc.272.49.30889  0.462
1997 Baorto DM, Gao Z, Malaviya R, Dustin ML, Van Der Merwe A, Lublin DM, Abraham SN. Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic Nature. 389: 636-639. PMID 9335508 DOI: 10.1038/39376  0.365
1997 Ganpule G, Knorr R, Miller JM, Carron CP, Dustin ML. Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions Journal of Immunology. 159: 2685-2692. PMID 9300688  0.371
1997 Knorr R, Dustin ML. The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)-1 and ICAM-3 in hydrodynamic flow Journal of Experimental Medicine. 186: 719-730. PMID 9271587 DOI: 10.1084/Jem.186.5.719  0.424
1997 Dustin ML. Adhesive bond dynamics in contacts between t lymphocytes and glass- supported planar bilayers reconstituted with the immunoglobulin-related adhesion molecule CD58 Journal of Biological Chemistry. 272: 15782-15788. PMID 9188475 DOI: 10.1074/Jbc.272.25.15782  0.453
1997 Shaw AS, Dustin ML. Making the T cell receptor go the distance: a topological view of T cell activation. Immunity. 6: 361-9. PMID 9133415 DOI: 10.1016/S1074-7613(00)80279-4  0.417
1997 Dustin ML, Bromley SK, Kan Z, Peterson DA, Unanue ER. Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 94: 3909-13. PMID 9108078 DOI: 10.1073/Pnas.94.8.3909  0.553
1996 Dustin ML, Ferguson LM, Chan PY, Springer TA, Golan DE. Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area. The Journal of Cell Biology. 132: 465-74. PMID 8636222 DOI: 10.1083/Jcb.132.3.465  0.62
1996 Kucik DF, Dustin ML, Miller JM, Brown EJ. Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes Journal of Clinical Investigation. 97: 2139-2144. PMID 8621804 DOI: 10.1172/Jci118651  0.396
1995 Miller J, Knorr R, Ferrone M, Houdei R, Carron CP, Dustin ML. Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1 Journal of Experimental Medicine. 182: 1231-1241. PMID 7595194 DOI: 10.1084/Jem.182.5.1231  0.473
1995 Meyer DM, Dustin ML, Carron CP. Characterization of intercellular adhesion molecule-1 ectodomain (sICAM-1) as an inhibitor of lymphocyte function-associated molecule-1 interaction with ICAM-1 Journal of Immunology. 155: 3578-3584. PMID 7561056  0.343
1992 Tözeren A, Sung KL, Sung LA, Dustin ML, Chan PY, Springer TA, Chien S. Micromanipulation of adhesion of a Jurkat cell to a planar bilayer membrane containing lymphocyte function-associated antigen 3 molecules. The Journal of Cell Biology. 116: 997-1006. PMID 1370839 DOI: 10.1083/Jcb.116.4.997  0.634
1992 Tözeren A, Mackie LH, Lawrence MB, Chan PY, Dustin ML, Springer TA. Micromanipulation of adhesion of phorbol 12-myristate-13-acetate-stimulated T lymphocytes to planar membranes containing intercellular adhesion molecule-1. Biophysical Journal. 63: 247-58. PMID 1358239 DOI: 10.1016/S0006-3495(92)81578-3  0.609
1992 Dustin ML, Carpen O, Springer TA. Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors. Journal of Immunology (Baltimore, Md. : 1950). 148: 2654-63. PMID 1349320  0.34
1991 Carpén O, Dustin ML, Springer TA, Swafford JA, Beckett LA, Caulfield JP. Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1, and two isoforms of LFA-3. The Journal of Cell Biology. 115: 861-71. PMID 1717493 DOI: 10.1083/Jcb.115.3.861  0.641
1991 Chan PY, Lawrence MB, Dustin ML, Ferguson LM, Golan DE, Springer TA. Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2. The Journal of Cell Biology. 115: 245-55. PMID 1717480 DOI: 10.1083/Jcb.115.1.245  0.594
1991 Dustin ML, Springer TA. Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annual Review of Immunology. 9: 27-66. PMID 1716919 DOI: 10.1146/Annurev.Iy.09.040191.000331  0.696
1991 Tozeren A, Sung KLP, Sung LA, Dustin ML, Chen PY, Springer TA, Chien S. Adherence strength of T cells to planar membranes containing LFA-3 molecules Annals of Biomedical Engineering. 19: 567-568.  0.35
1990 Dustin ML. Two-way signalling through the LFA-1 lymphocyte adhesion receptor Bioessays. 12: 421-427. PMID 2256906 DOI: 10.1002/Bies.950120905  0.472
1990 Staunton DE, Dustin ML, Erickson HP, Springer TA. The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell. 61: 243-54. PMID 1970514 DOI: 10.1016/0092-8674(90)90805-O  0.507
1989 Frohman EM, Frohman TC, Dustin ML, Vayuvegula B, Choi B, Gupta A, Noort SVD, Gupta S. The induction of intercellular adhesion molecule 1 (ICAM-1) expression on human fetal astrocytes by interferon-λ, tumor necrosis factor α, lymphotoxin, and interleukin-1: relevance to intracerebral antigen presentation Journal of Neuroimmunology. 23: 117-124. PMID 2656754 DOI: 10.1016/0165-5728(89)90030-1  0.426
1989 Dustin ML, Garcia-Aguilar J, Hibbs ML, Larson RS, Stacker SA, Staunton DE, Wardlaw AJ, Springer TA. Structure and regulation of the leukocyte adhesion receptor LFA-1 and its counterreceptors, ICAM-1 and ICAM-2. Cold Spring Harbor Symposia On Quantitative Biology. 54: 753-65. PMID 2577025 DOI: 10.1101/Sqb.1989.054.01.089  0.487
1989 Kishimoto TK, Larson RS, Corbi AL, Dustin ML, Staunton DE, Springer TA. The leukocyte integrins. Advances in Immunology. 46: 149-82. PMID 2551146 DOI: 10.1016/S0065-2776(08)60653-7  0.496
1989 Staunton DE, Dustin ML, Springer TA. Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature. 339: 61-4. PMID 2497351 DOI: 10.1038/339061A0  0.63
1989 Dustin ML, Springer TA. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature. 341: 619-24. PMID 2477710 DOI: 10.1038/341619A0  0.652
1989 Staunton DE, Fisher RC, LeBeau MM, Lawrence JB, Barton DE, Francke U, Dustin M, Thorley-Lawson DA. Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and MAPS to chromosome 1q21-23 Journal of Experimental Medicine. 169: 10876-1099. PMID 2466936 DOI: 10.1084/Jem.169.3.1087  0.36
1989 Dustin ML, Olive D, Springer TA. Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function-associated antigen 3. The Journal of Experimental Medicine. 169: 503-17. PMID 2463330 DOI: 10.1084/Jem.169.2.503  0.623
1988 Staunton DE, Marlin SD, Stratowa C, Dustin ML, Springer TA. Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell. 52: 925-33. PMID 3349522 DOI: 10.1016/0092-8674(88)90434-5  0.539
1988 Makgoba MW, Sanders ME, Ginther Luce GE, Dustin ML, Springer TA, Clark EA, Mannoni P, Shaw S. ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells. Nature. 331: 86-8. PMID 3277059 DOI: 10.1038/331086A0  0.592
1988 Dustin ML, Springer TA. Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. The Journal of Cell Biology. 107: 321-31. PMID 3134364 DOI: 10.1083/Jcb.107.1.321  0.599
1988 Dustin ML, Singer KH, Tuck DT, Springer TA. Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1). The Journal of Experimental Medicine. 167: 1323-40. PMID 3128630 DOI: 10.1084/Jem.167.4.1323  0.639
1988 Dustin ML, Staunton DE, Springer TA. Supergene families meet in the immune system. Immunology Today. 9: 213-5. PMID 3076418 DOI: 10.1016/0167-5699(88)91216-9  0.642
1988 Makgoba MW, Sanders ME, Ginther Luce GE, Gugel EA, Dustin ML, Springer TA, Shaw S. Functional evidence that intercellular adhesion molecule-1 (ICAM-1) is a ligand for LFA-1-dependent adhesion in T cell-mediated cytotoxicity. European Journal of Immunology. 18: 637-40. PMID 2896596 DOI: 10.1002/Eji.1830180423  0.635
1988 Denning SM, Dustin ML, Springer TA, Singer KH, Haynes BF. Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway. Journal of Immunology (Baltimore, Md. : 1950). 141: 2980-5. PMID 2459236  0.35
1988 MAKGOBA MW, SANDERS ME, LUCE GEG, GUGEL EA, DUSTIN ML, SPRINGER TA, SHAW S. Intercellular Adhesion Molecule-1 (ICAM-1) Monoclonal Antibody Inhibits Cytotoxic T Lymphocyte Recognition Annals of the New York Academy of Sciences. 532: 427-428. DOI: 10.1111/J.1749-6632.1988.Tb36364.X  0.562
1987 Dustin ML, Selvaraj P, Mattaliano RJ, Springer TA. Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface. Nature. 329: 846-8. PMID 3313053 DOI: 10.1038/329846A0  0.512
1987 Wallner BP, Frey AZ, Tizard R, Mattaliano RJ, Hession C, Sanders ME, Dustin ML, Springer TA. Primary structure of lymphocyte function-associated antigen 3 (LFA-3). The ligand of the T lymphocyte CD2 glycoprotein. The Journal of Experimental Medicine. 166: 923-32. PMID 3309127 DOI: 10.1084/Jem.166.4.923  0.565
1987 Selvaraj P, Dustin ML, Silber R, Low MG, Springer TA. Deficiency of lymphocyte function-associated antigen 3 (LFA-3) in paroxysmal nocturnal hemoglobinuria. Functional correlates and evidence for a phosphatidylinositol membrane anchor. The Journal of Experimental Medicine. 166: 1011-25. PMID 3309123 DOI: 10.1084/Jem.166.4.1011  0.621
1987 Springer TA, Dustin ML, Kishimoto TK, Marlin SD. The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system. Annual Review of Immunology. 5: 223-52. PMID 3109455 DOI: 10.1146/Annurev.Iy.05.040187.001255  0.651
1987 Dustin ML, Sanders ME, Shaw S, Springer TA. Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion. The Journal of Experimental Medicine. 165: 677-92. PMID 3102676 DOI: 10.1084/Jem.165.3.677  0.65
1987 Plunkett ML, Sanders ME, Selvaraj P, Dustin ML, Springer TA. Rosetting of activated human T lymphocytes with autologous erythrocytes. Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 (LFA-3). The Journal of Experimental Medicine. 165: 664-76. PMID 3102675 DOI: 10.1084/Jem.165.3.664  0.63
1987 Selvaraj P, Plunkett ML, Dustin M, Sanders ME, Shaw S, Springer TA. The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3. Nature. 326: 400-3. PMID 2951597 DOI: 10.1038/326400A0  0.675
1987 Tiefenthaler G, Hünig T, Dustin ML, Springer TA, Meuer SC. Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation. European Journal of Immunology. 17: 1847-50. PMID 2891540 DOI: 10.1002/Eji.1830171227  0.676
1987 Tiefenthaler G, Dustin ML, Springer TA, Hünig T. Serologic cross-reactivity of T11 target structure and lymphocyte function-associated antigen 3. Evidence for structural homology of the sheep and human ligands of CD2. Journal of Immunology (Baltimore, Md. : 1950). 139: 2696-701. PMID 2443569  0.314
1986 Rothlein R, Dustin ML, Marlin SD, Springer TA. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. Journal of Immunology (Baltimore, Md. : 1950). 137: 1270-4. PMID 3525675  0.36
1986 Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). Journal of Immunology (Baltimore, Md. : 1950). 137: 245-54. PMID 3086451  0.35
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