| Year |
Citation |
Score |
| 2022 |
Lancaster EB, Johnson WH, LeVieux JA, Hardtke HA, Zhang YJ, Whitman CP. A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway. Archives of Biochemistry and Biophysics. 733: 109471. PMID 36522814 DOI: 10.1016/j.abb.2022.109471 |
0.495 |
|
| 2022 |
Lancaster EB, Yang W, Johnson WH, Baas BJ, Zhang YJ, Whitman CP. Kinetic, Inhibition, and Structural Characterization of a Malonate Semialdehyde Decarboxylase-like Protein from sp. PCC 6303: A Gateway to the non-Pro1 Tautomerase Superfamily Members. Biochemistry. PMID 35559608 DOI: 10.1021/acs.biochem.2c00101 |
0.331 |
|
| 2021 |
Baas BJ, Medellin BP, LeVieux JA, Erwin K, Lancaster EB, Johnson WH, Kaoud TS, Moreno RY, de Ruijter M, Babbitt PC, Zhang YJ, Whitman CP. Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications. Biochemistry. PMID 34019384 DOI: 10.1021/acs.biochem.1c00220 |
0.608 |
|
| 2020 |
Medellin BP, Lancaster EB, Brown S, Rakhade S, Babbitt PC, Whitman CP, Zhang YJ. Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer. Biochemistry. PMID 32242662 DOI: 10.1021/Acs.Biochem.0C00211 |
0.583 |
|
| 2019 |
Erwin KL, Johnson WH, Meichan AJ, Whitman CP. Preparation of dihydroxy polycyclic aromatic hydrocarbons and activities of two dioxygenases in the phenanthrene degradative pathway. Archives of Biochemistry and Biophysics. 108081. PMID 31445023 DOI: 10.1016/J.Abb.2019.108081 |
0.362 |
|
| 2019 |
Baas BJ, Medellin BP, LeVieux J, de Ruijter M, Zhang YJ, Brown SD, Akiva E, Babbitt PC, Whitman CP. Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer. Biochemistry. PMID 31074977 DOI: 10.1021/Acs.Biochem.9B00303 |
0.641 |
|
| 2018 |
Haugland JO, Kinney KA, Johnson WH, Camino MMA, Whitman CP, Lawler DF. Laccase removal of 2-chlorophenol and sulfamethoxazole in municipal wastewater. Water Environment Research : a Research Publication of the Water Environment Federation. PMID 30802358 DOI: 10.1002/Wer.1006 |
0.354 |
|
| 2018 |
LeVieux J, Medellin BP, Johnson WH, Erwin K, Li W, Johnson IA, Zhang YJ, Whitman CP. Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for Specificity, Catalysis, and the N-acetylneuraminate lyase subgroup of the Aldolase Superfamily. Biochemistry. PMID 29856600 DOI: 10.1021/Acs.Biochem.8B00532 |
0.488 |
|
| 2018 |
Stack TMM, Li W, Johnson WH, Zhang YJ, Whitman CP. Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry. PMID 29303557 DOI: 10.1021/Acs.Biochem.7B00899 |
0.416 |
|
| 2017 |
Davidson R, Baas BJ, Akiva E, Holliday GL, Polacco BJ, LeVieux JA, Pullara CR, Zhang YJ, Whitman CP, Babbitt PC. A global view of structure-function relationships in the tautomerase superfamily. The Journal of Biological Chemistry. PMID 29184004 DOI: 10.1074/Jbc.M117.815340 |
0.645 |
|
| 2017 |
LeVieux JA, Baas BJ, Kaoud TS, Davidson R, Babbitt PC, Zhang YJ, Whitman CP. Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily. Archives of Biochemistry and Biophysics. PMID 29111295 DOI: 10.1016/J.Abb.2017.10.018 |
0.706 |
|
| 2017 |
Stack TMM, Jr WHJ, Whitman CP. Synthesis and enzymatic ketonization of the 5-(halo)-2-hydroxymuconates and 5-(halo)-2-hydroxy-2,4-pentadienoates. Beilstein Journal of Organic Chemistry. 13: 1022-1031. PMID 28684981 DOI: 10.3762/Bjoc.13.101 |
0.35 |
|
| 2017 |
Huddleston JP, Wang SC, Johnson KA, Whitman CP. Resolution of the uncertainty in the kinetic mechanism for the trans-3-Chloroacrylic acid dehalogenase-catalyzed reaction. Archives of Biochemistry and Biophysics. PMID 28499743 DOI: 10.1016/J.Abb.2017.05.004 |
0.445 |
|
| 2016 |
Johnson WH, Stack TM, Taylor SM, Burks EA, Whitman CP. The Stereochemical Consequences of Vinylpyruvate Hydratase-catalyzed Reactions. Biochemistry. PMID 27362840 DOI: 10.1021/Acs.Biochem.6B00552 |
0.404 |
|
| 2016 |
Guimarães SL, Coitinho JB, Costa DM, Araújo SS, Whitman CP, Nagem RA. Crystal structures of apo and liganded 4-oxalocrotonate decarboxylase uncover a structural basis for the metal-assisted decarboxylation of a vinylogous β-keto acid. Biochemistry. PMID 27082660 DOI: 10.1021/Acs.Biochem.6B00050 |
0.496 |
|
| 2016 |
LeVieux JA, Johnson WH, Erwin K, Li W, Jessie Zhang Y, Whitman CP. The bacterial catabolism of polycyclic aromatic hydrocarbons: Characterization of three hydratase-aldolase-catalyzed reactions Perspectives in Science. 9: 33-41. DOI: 10.1016/J.Pisc.2016.03.025 |
0.443 |
|
| 2015 |
Araújo SS, Neves CM, Guimarães SL, Whitman CP, Johnson WH, Aparicio R, Nagem RA. Structural and kinetic characterization of recombinant 2-hydroxymuconate semialdehyde dehydrogenase from Pseudomonas putida G7. Archives of Biochemistry and Biophysics. 579: 8-17. PMID 26032336 DOI: 10.1016/J.Abb.2015.05.006 |
0.431 |
|
| 2015 |
Huddleston JP, Johnson WH, Schroeder GK, Whitman CP. Reactions of Cg10062, a cis-3-Chloroacrylic Acid Dehalogenase Homologue, with Acetylene and Allene Substrates: Evidence for a Hydration-Dependent Decarboxylation. Biochemistry. 54: 3009-23. PMID 25894805 DOI: 10.1021/Acs.Biochem.5B00240 |
0.527 |
|
| 2015 |
Huddleston JP, Johnson WH, Schroeder GK, Whitman CP. The accidental assignment of function in the tautomerase superfamily Perspectives in Science. 4: 38-45. DOI: 10.1016/J.Pisc.2014.12.007 |
0.503 |
|
| 2014 |
Huddleston JP, Burks EA, Whitman CP. Identification and characterization of new family members in the tautomerase superfamily: analysis and implications. Archives of Biochemistry and Biophysics. 564: 189-96. PMID 25219626 DOI: 10.1016/J.Abb.2014.08.019 |
0.396 |
|
| 2014 |
Hackert M, Guo Y, Johnson, Jr. W, Whitman C. Comparison of the Structures and Activities of Cg10062 with other 4-OT Enzymes Acta Crystallographica Section a Foundations and Advances. 70: C1645-C1645. DOI: 10.1107/S2053273314083545 |
0.763 |
|
| 2013 |
Cornish-Bowden A, Whitman CP. A century of Michaelis--Menten kinetics. Introduction. Febs Letters. 587: 2711. PMID 23899672 DOI: 10.1016/J.Febslet.2013.07.035 |
0.303 |
|
| 2013 |
Poelarends GJ, Serrano H, Huddleston JP, Johnson WH, Whitman CP. A mutational analysis of active site residues in trans-3-chloroacrylic acid dehalogenase. Febs Letters. 587: 2842-50. PMID 23851010 DOI: 10.1016/J.Febslet.2013.07.006 |
0.725 |
|
| 2013 |
Terrell CR, Burks EA, Whitman CP, Hoffman DW. Structural and kinetic characterization of two 4-oxalocrotonate tautomerases in Methylibium petroleiphilum strain PM1. Archives of Biochemistry and Biophysics. 537: 113-24. PMID 23831510 DOI: 10.1016/J.Abb.2013.06.016 |
0.387 |
|
| 2013 |
Guo Y, Serrano H, Poelarends GJ, Johnson WH, Hackert ML, Whitman CP. Kinetic, mutational, and structural analysis of malonate semialdehyde decarboxylase from Coryneform bacterium strain FG41: mechanistic implications for the decarboxylase and hydratase activities. Biochemistry. 52: 4830-41. PMID 23781927 DOI: 10.1021/Bi400567A |
0.814 |
|
| 2013 |
Schroeder GK, Huddleston JP, Johnson WH, Whitman CP. A mutational analysis of the active site loop residues in cis-3-Chloroacrylic acid dehalogenase. Biochemistry. 52: 4204-16. PMID 23692140 DOI: 10.1021/Bi4004414 |
0.503 |
|
| 2012 |
Huddleston JP, Schroeder GK, Johnson KA, Whitman CP. A pre-steady state kinetic analysis of the αY60W mutant of trans-3-chloroacrylic acid dehalogenase: implications for the mechanism of the wild-type enzyme. Biochemistry. 51: 9420-35. PMID 23110338 DOI: 10.1021/Bi3010686 |
0.522 |
|
| 2012 |
Schroeder GK, Johnson WH, Huddleston JP, Serrano H, Johnson KA, Whitman CP. Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine. Journal of the American Chemical Society. 134: 293-304. PMID 22129074 DOI: 10.1021/Ja206873F |
0.707 |
|
| 2011 |
Burks EA, Yan W, Johnson WH, Li W, Schroeder GK, Min C, Gerratana B, Zhang Y, Whitman CP. Kinetic, crystallographic, and mechanistic characterization of TomN: elucidation of a function for a 4-oxalocrotonate tautomerase homologue in the tomaymycin biosynthetic pathway. Biochemistry. 50: 7600-11. PMID 21809870 DOI: 10.1021/Bi200947W |
0.497 |
|
| 2011 |
Guo Y, Serrano H, Johnson WH, Ernst S, Hackert ML, Whitman CP. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanisms. Bioorganic Chemistry. 39: 1-9. PMID 21074239 DOI: 10.1016/J.Bioorg.2010.10.001 |
0.817 |
|
| 2010 |
Almrud JJ, Dasgupta R, Czerwinski RM, Kern AD, Hackert ML, Whitman CP. Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members. Bioorganic Chemistry. 38: 252-9. PMID 20709352 DOI: 10.1016/J.Bioorg.2010.07.002 |
0.739 |
|
| 2010 |
Burks EA, Fleming CD, Mesecar AD, Whitman CP, Pegan SD. Kinetic and structural characterization of a heterohexamer 4-oxalocrotonate tautomerase from Chloroflexus aurantiacus J-10-fl: implications for functional and structural diversity in the tautomerase superfamily . Biochemistry. 49: 5016-27. PMID 20465238 DOI: 10.1021/Bi100502Z |
0.51 |
|
| 2010 |
Srivastava D, Zhu W, Johnson WH, Whitman CP, Becker DF, Tanner JJ. The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction. Biochemistry. 49: 560-9. PMID 19994913 DOI: 10.1021/Bi901717S |
0.43 |
|
| 2009 |
Robertson BA, Schroeder GK, Jin Z, Johnson KA, Whitman CP. Pre-steady-state kinetic analysis of cis-3-chloroacrylic acid dehalogenase: analysis and implications. Biochemistry. 48: 11737-44. PMID 19856961 DOI: 10.1021/Bi901349Z |
0.727 |
|
| 2009 |
Sevastik R, Whitman CP, Himo F. Reaction mechanism of cis-3-chloroacrylic acid dehalogenase: a theoretical study. Biochemistry. 48: 9641-9. PMID 19725565 DOI: 10.1021/Bi900879A |
0.469 |
|
| 2008 |
Pegan SD, Serrano H, Whitman CP, Mesecar AD. Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity. Acta Crystallographica. Section D, Biological Crystallography. 64: 1277-82. PMID 19018104 DOI: 10.1107/S0907444908034707 |
0.737 |
|
| 2008 |
Poelarends GJ, Veetil VP, Whitman CP. The chemical versatility of the β-α-β fold: Catalytic promiscuity and divergent evolution in the tautomerase superfamily Cellular and Molecular Life Sciences. 65: 3606-3618. PMID 18695941 DOI: 10.1007/S00018-008-8285-X |
0.466 |
|
| 2008 |
Robertson BA, Johnson WH, Lo HH, Whitman CP. Inactivation of Cg10062, a cis-3-chloroacrylic acid dehalogenase homologue in Corynebacterium glutamicum, by (R)- and (S)-oxirane-2-carboxylate: analysis and implications. Biochemistry. 47: 8796-803. PMID 18646866 DOI: 10.1021/Bi800790Y |
0.708 |
|
| 2008 |
Poelarends GJ, Serrano H, Person MD, Johnson WH, Whitman CP. Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily. Biochemistry. 47: 8139-47. PMID 18598055 DOI: 10.1021/Bi8007388 |
0.732 |
|
| 2008 |
White TA, Johnson WH, Whitman CP, Tanner JJ. Structural basis for the inactivation of Thermus thermophilus proline dehydrogenase by N-propargylglycine. Biochemistry. 47: 5573-80. PMID 18426222 DOI: 10.1021/Bi800055W |
0.436 |
|
| 2008 |
Hackert M, Ernst S, Guo Y, Serrano H, Johnson W, Whitman C. Flexibility in active site ofcis-3-chloroacrylic acid dehalogenase revealed by multiple structures Acta Crystallographica Section a Foundations of Crystallography. 64: C278-C279. DOI: 10.1107/S0108767308091095 |
0.744 |
|
| 2007 |
Wang SC, Johnson WH, Czerwinski RM, Stamps SL, Whitman CP. Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions. Biochemistry. 46: 11919-29. PMID 17902707 DOI: 10.1021/Bi701231A |
0.443 |
|
| 2007 |
Poelarends GJ, Johnson WH, Serrano H, Whitman CP. Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction? Biochemistry. 46: 9596-604. PMID 17661448 DOI: 10.1021/Bi7007189 |
0.727 |
|
| 2007 |
de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate. The Journal of Biological Chemistry. 282: 2440-9. PMID 17121835 DOI: 10.1074/Jbc.M608134200 |
0.735 |
|
| 2006 |
Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH, Hackert ML, Whitman CP. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase. Biochemistry. 45: 7700-8. PMID 16784221 DOI: 10.1021/Bi0600603 |
0.743 |
|
| 2006 |
Golubkov PA, Johnson WH, Czerwinski RM, Person MD, Wang SC, Whitman CP, Hackert ML. Inactivation of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor by 2-oxo-4-phenyl-3-butynoate. Bioorganic Chemistry. 34: 183-99. PMID 16780921 DOI: 10.1016/J.Bioorg.2006.05.001 |
0.715 |
|
| 2005 |
Almrud JJ, Poelarends GJ, Johnson WH, Serrano H, Hackert ML, Whitman CP. Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities. Biochemistry. 44: 14818-27. PMID 16274229 DOI: 10.1021/Bi051383M |
0.785 |
|
| 2005 |
Poelarends GJ, Serrano H, Johnson WH, Whitman CP. Inactivation of malonate semialdehyde decarboxylase by 3-halopropiolates: evidence for hydratase activity. Biochemistry. 44: 9375-81. PMID 15982004 DOI: 10.1021/Bi050296R |
0.754 |
|
| 2005 |
Azurmendi HF, Miller SG, Whitman CP, Mildvan AS. Half-of-the-sites binding of reactive intermediates and their analogues to 4-oxalocrotonate tautomerase and induced structural asymmetry of the enzyme. Biochemistry. 44: 7725-37. PMID 15909987 DOI: 10.1021/Bi0502590 |
0.43 |
|
| 2005 |
Gunsch CK, Cheng Q, Kinney KA, Szaniszlo PJ, Whitman CP. Identification of a homogentisate-1,2-dioxygenase gene in the fungus Exophiala lecanii-corni: analysis and implications. Applied Microbiology and Biotechnology. 68: 405-11. PMID 15731901 DOI: 10.1007/S00253-005-1899-0 |
0.341 |
|
| 2004 |
Poelarends GJ, Serrano H, Johnson WH, Hoffman DW, Whitman CP. The hydratase activity of malonate semialdehyde decarboxylase: mechanistic and evolutionary implications. Journal of the American Chemical Society. 126: 15658-9. PMID 15571384 DOI: 10.1021/Ja044304N |
0.725 |
|
| 2004 |
Poelarends GJ, Whitman CP. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural studies of the 1,3-dichloropropene catabolic enzymes. Bioorganic Chemistry. 32: 376-92. PMID 15381403 DOI: 10.1016/J.Bioorg.2004.05.006 |
0.55 |
|
| 2004 |
Johnson WH, Wang SC, Stanley TM, Czerwinski RM, Almrud JJ, Poelarends GJ, Murzin AG, Whitman CP. 4-Oxalocrotonate tautomerase, its homologue YwhB, and active vinylpyruvate hydratase: synthesis and evaluation of 2-fluoro substrate analogues. Biochemistry. 43: 10490-501. PMID 15301547 DOI: 10.1021/Bi049489P |
0.464 |
|
| 2004 |
Poelarends GJ, Serrano H, Johnson WH, Whitman CP. Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications. Biochemistry. 43: 7187-96. PMID 15170356 DOI: 10.1021/Bi049823H |
0.743 |
|
| 2004 |
Azurmendi HF, Wang SC, Massiah MA, Poelarends GJ, Whitman CP, Mildvan AS. The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis. Biochemistry. 43: 4082-91. PMID 15065850 DOI: 10.1021/Bi030241U |
0.522 |
|
| 2004 |
Cheng Q, Kinney KA, Whitman CP, Szaniszlo PJ. Characterization of two polyketide synthase genes in Exophiala lecanii-corni, a melanized fungus with bioremediation potential. Bioorganic Chemistry. 32: 92-108. PMID 14990308 DOI: 10.1016/J.Bioorg.2003.10.001 |
0.322 |
|
| 2004 |
Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases. Biochemistry. 43: 759-72. PMID 14730981 DOI: 10.1021/Bi0355948 |
0.734 |
|
| 2004 |
Wang SC, Johnson WH, Czerwinski RM, Whitman CP. Reactions of 4-oxalocrotonate tautomerase and YwhB with 3-halopropiolates: analysis and implications. Biochemistry. 43: 748-58. PMID 14730980 DOI: 10.1021/Bi035495U |
0.507 |
|
| 2004 |
de Jong RM, Brugman W, Poelarends GJ, Whitman CP, Dijkstra BW. The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily. The Journal of Biological Chemistry. 279: 11546-52. PMID 14701869 DOI: 10.1074/Jbc.M311966200 |
0.403 |
|
| 2003 |
Wang SC, Johnson WH, Whitman CP. The 4-oxalocrotonate tautomerase- and YwhB-catalyzed hydration of 3E-haloacrylates: implications for the evolution of new enzymatic activities. Journal of the American Chemical Society. 125: 14282-3. PMID 14624569 DOI: 10.1021/Ja0370948 |
0.473 |
|
| 2003 |
Poelarends GJ, Johnson WH, Murzin AG, Whitman CP. Mechanistic characterization of a bacterial malonate semialdehyde decarboxylase: identification of a new activity on the tautomerase superfamily. The Journal of Biological Chemistry. 278: 48674-83. PMID 14506256 DOI: 10.1074/Jbc.M306706200 |
0.524 |
|
| 2003 |
Wang SC, Person MD, Johnson WH, Whitman CP. Reactions of trans-3-chloroacrylic acid dehalogenase with acetylene substrates: consequences of and evidence for a hydration reaction. Biochemistry. 42: 8762-73. PMID 12873137 DOI: 10.1021/Bi034598+ |
0.503 |
|
| 2002 |
Almrud JJ, Kern AD, Wang SC, Czerwinski RM, Johnson WH, Murzin AG, Hackert ML, Whitman CP. The crystal structure of YdcE, a 4-oxalocrotonate tautomerase homologue from Escherichia coli, confirms the structural basis for oligomer diversity. Biochemistry. 41: 12010-24. PMID 12356301 DOI: 10.1021/Bi020271H |
0.693 |
|
| 2002 |
Whitman CP. The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif. Archives of Biochemistry and Biophysics. 402: 1-13. PMID 12051677 DOI: 10.1016/S0003-9861(02)00052-8 |
0.52 |
|
| 2002 |
Hackert ML, Almrud JJ, Wang SC, Johnson WH, Whitman CP. Structural and functional diversity within the 4-OT family of enzymes Acta Crystallographica Section a Foundations of Crystallography. 58: c101-c101. DOI: 10.1107/S0108767302089079 |
0.659 |
|
| 2001 |
Czerwinski RM, Harris TK, Massiah MA, Mildvan AS, Whitman CP. The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50. Biochemistry. 40: 1984-95. PMID 11329265 DOI: 10.1021/Bi0024714 |
0.462 |
|
| 2000 |
Stamps SL, Taylor AB, Wang SC, Hackert ML, Whitman CP. Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants. Biochemistry. 39: 9671-8. PMID 10933783 DOI: 10.1021/Bi000373C |
0.723 |
|
| 2000 |
Stanley TM, Johnson WH, Burks EA, Whitman CP, Hwang CC, Cook PF. Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase. Biochemistry. 39: 718-26. PMID 10651637 DOI: 10.1021/Bi9918902 |
0.379 |
|
| 1999 |
Johnson WH, Czerwinski RM, Stamps SL, Whitman CP. A kinetic and stereochemical investigation of the role of lysine-32 in the phenylpyruvate tautomerase activity catalyzed by macrophage migration inhibitory factor Biochemistry. 38: 16024-16033. PMID 10625471 DOI: 10.1021/Bi991825S |
0.491 |
|
| 1999 |
Hermanowski-Vosatka A, Mundt SS, Ayala JM, Goyal S, Hanlon WA, Czerwinski RM, Wright SD, Whitman CP. Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration Biochemistry. 38: 12841-12849. PMID 10504254 DOI: 10.1021/Bi991352P |
0.424 |
|
| 1999 |
Czerwinski RM, Harris TK, Johnson WH, Legler PM, Stivers JT, Mildvan AS, Whitman CP. Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the pKa values of active site residues and on the pH dependence of catalysis. Biochemistry. 38: 12358-66. PMID 10493803 DOI: 10.1021/Bi9911177 |
0.451 |
|
| 1999 |
Harris TK, Czerwinski RM, Johnson WH, Legler PM, Abeygunawardana C, Massiah MA, Stivers JT, Whitman CP, Mildvan AS. Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase. Biochemistry. 38: 12343-57. PMID 10493802 DOI: 10.1021/Bi991116E |
0.497 |
|
| 1999 |
Taylor AB, Johnson WH, Czerwinski RM, Li HS, Hackert ML, Whitman CP. Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition. Biochemistry. 38: 7444-52. PMID 10360941 DOI: 10.1021/Bi9904048 |
0.711 |
|
| 1999 |
Gadda G, Dangott LJ, Johnson WH, Whitman CP, Fitzpatrick PF. Characterization of 2-oxo-3-pentynoate as an active-site-directed inactivator of flavoprotein oxidases: identification of active-site peptides in tryptophan 2-monooxygenase. Biochemistry. 38: 5822-8. PMID 10231533 DOI: 10.1021/Bi982777Z |
0.458 |
|
| 1998 |
Taylor AB, Czerwinski RM, Johnson WH, Whitman CP, Hackert ML. Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis. Biochemistry. 37: 14692-700. PMID 9778344 DOI: 10.1021/Bi981607J |
0.709 |
|
| 1998 |
Stamps SL, Fitzgerald MC, Whitman CP. Characterization of the role of the amino-terminal proline in the enzymatic activity catalyzed by macrophage migration inhibitory factor. Biochemistry. 37: 10195-202. PMID 9665726 DOI: 10.1021/Bi9806955 |
0.511 |
|
| 1998 |
Burks EA, Johnson WH, Whitman CP. Stereochemical and isotopic labeling studies of 2-oxo-hept-4-ene-1,7- dioate hydratase: Evidence for an enzyme-catalyzed ketonization step in the hydration reaction Journal of the American Chemical Society. 120: 7665-7675. DOI: 10.1021/Ja9808402 |
0.45 |
|
| 1998 |
Lian H, Czerwinski RM, Stanley TM, Johnson WH, Watson RJ, Whitman CP. The contribution of the substrate's carboxylate group to the mechanism of 4-oxalocrotonate tautomerase Bioorganic Chemistry. 26: 141-156. DOI: 10.1006/Bioo.1998.1095 |
0.469 |
|
| 1997 |
Johnson WH, Czerwinski RM, Fitzgerald MC, Whitman CP. Inactivation of 4-oxalocrotonate tautomerase by 2-oxo-3-pentynoate. Biochemistry. 36: 15724-32. PMID 9398301 DOI: 10.1021/Bi971608W |
0.512 |
|
| 1997 |
Czerwinski RM, Johnson WH, Whitman CP, Harris TK, Abeygunawardana C, Mildvan AS. Kinetic and structural effects of mutations of the catalytic amino- terminal proline in 4-oxalocrotonate tautomerase Biochemistry. 36: 14551-14560. PMID 9398173 DOI: 10.1021/Bi971545H |
0.476 |
|
| 1996 |
Stivers JT, Abeygunawardana C, Whitman CP, Mildvan AS. 4-Oxalocrotonate tautomerase, a 41-kDa homohexamer: backbone and side-chain resonance assignments, solution secondary structure, and location of active site residues by heteronuclear NMR spectroscopy. Protein Science : a Publication of the Protein Society. 5: 729-41. PMID 8845763 DOI: 10.1002/Pro.5560050418 |
0.406 |
|
| 1996 |
Fitzgerald MC, Chernushevich I, Standing KG, Whitman CP, Kent SB. Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 93: 6851-6. PMID 8692908 DOI: 10.1073/Pnas.93.14.6851 |
0.413 |
|
| 1996 |
Stivers JT, Abeygunawardana C, Mildvan AS, Hajipour G, Whitman CP. 4-Oxalocrotonate tautomerase: pH dependence of catalysis and pKa values of active site residues. Biochemistry. 35: 814-23. PMID 8547261 DOI: 10.1021/Bi9510789 |
0.386 |
|
| 1996 |
Stivers JT, Abeygunawardana C, Mildvan AS, Hajipour G, Whitman CP, Chen LH. Catalytic role of the amino-terminal proline in 4-oxalocrotonate tautomerase: affinity labeling and heteronuclear NMR studies. Biochemistry. 35: 803-13. PMID 8547260 DOI: 10.1021/Bi951077G |
0.428 |
|
| 1996 |
Taylor AB, Whitman CP, Hackert ML. Structure and crystal packing studies of 4-oxalocrotonate tautomerase Acta Crystallographica Section a Foundations of Crystallography. 52: C124-C124. DOI: 10.1107/S0108767396094214 |
0.619 |
|
| 1995 |
Fitzgerald MC, Chernushevich I, Standing KG, Kent SBH, Whitman CP. Total chemical synthesis and catalytic properties of the enzyme enantiomers L- and D-4-oxalocrotonate tautomerase Journal of the American Chemical Society. 117: 11075-11080. DOI: 10.1021/Ja00150A006 |
0.34 |
|
| 1995 |
Johnson WH, Hajipour G, Whitman CP. Stereochemical studies of 5-(carboxymethyl)-2-hydroxymuconate isomerase and 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase from Escherichia coli C: Mechanistic and evolutionary implications Journal of the American Chemical Society. 117: 8719-8726. DOI: 10.1021/Ja00139A004 |
0.434 |
|
| 1994 |
Lian H, Whitman CP. Stereochemical and isotopic labeling studies of 4-oxalocrotonate decarboxylase and vinylpyruvate hydratase: Analysis and mechanistic implications Journal of the American Chemical Society. 116: 10403-10411. DOI: 10.1021/Ja00102A007 |
0.338 |
|
| 1993 |
Lian H, Whitman CP. Ketonization of 2-hydroxy-2,4-pentadienoate by 4-oxalocrotonate tautomerase: Implications for the stereochemical course and the mechanism Journal of the American Chemical Society. 115: 7978-7984. DOI: 10.1021/Ja00071A007 |
0.417 |
|
| 1993 |
Hajipour G, Johnson WH, Dauben PD, Stolowich NJ, Whitman CP. Chemical and enzymatic ketonization of 5-(carboxymethyl)-2-hydroxymuconate Journal of the American Chemical Society. 115: 3533-3542. DOI: 10.1021/Ja00062A018 |
0.44 |
|
| 1992 |
Chen LH, Kenyon GL, Curtin F, Harayama S, Bembenek ME, Hajipour G, Whitman CP. 4-Oxalocrotonate tautomerase, an enzyme composed of 62 amino acid residues per monomer. The Journal of Biological Chemistry. 267: 17716-21. PMID 1339435 |
0.595 |
|
| 1992 |
Johnson WH, Hajipour G, Whitman CP. Characterization of a dienol intermediate in the 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase reaction Journal of the American Chemical Society. 114: 11001-11003. DOI: 10.1021/Ja00053A070 |
0.323 |
|
| 1992 |
Whitman CP, Hajipour G, Watson RJ, Johnson WH, Bembenek MH, Stolowich NJ. Stereospecific ketonization of 2-hydroxymuconate by 4-oxalocrotonate tautomerase and 5-(carboxymethyl)-2-hydroxymuconate isomerase Journal of the American Chemical Society. 114: 10104-10110. DOI: 10.1021/Ja00052A002 |
0.458 |
|
| 1991 |
Whitman CP, Aird BA, Gillespie WR, Stolowich NJ. Chemical and enzymatic ketonization of 2-hydroxymuconate, a conjugated enol Journal of the American Chemical Society. 113: 3154-3162. DOI: 10.1021/Ja00008A052 |
0.44 |
|
| 1988 |
Lin DT, Powers VM, Reynolds LJ, Whitman CP, Kozarich JW, Kenyon GL. Evidence for the generation of .alpha.-carboxy-.alpha.-hydroxy-p-xylylene from p-(bromomethyl)mandelate by mandelate racemase Journal of the American Chemical Society. 110: 323-324. DOI: 10.1021/Ja00209A069 |
0.43 |
|
| 1988 |
Lin DT, Powers VM, Reynolds LJ, Whitman CP, Kozarich JW, Kenyon GL. Evidence for the generation of α-carboxy-α-hydroxy-p-xylylene from p-(bromomethyl)mandelate by mandelate racemase Journal of the American Chemical Society. 110: 323-324. |
0.428 |
|
| 1987 |
Chari RVJ, Whitman CP, Kozarich JW, Ngai KL, Ornston LN. Absolute stereochemical course of the 3-carboxymuconate cycloisomerases from Pseudomonas putida and Acinetobacter calcoaceticus: Analysis and implications Journal of the American Chemical Society. 109: 5514-5519. DOI: 10.1021/Ja00252A034 |
0.343 |
|
| 1985 |
Whitman CP, Hegeman GD, Cleland WW, Kenyon GL. Symmetry and asymmetry in mandelate racemase catalysis. Biochemistry. 24: 3936-42. PMID 2996586 DOI: 10.1021/Bi00336A020 |
0.563 |
|
| 1985 |
Whitman CP, Craig JC, Kenyon GL. Synthesis, chiroptical properties and absolute configuration of α-phenylglycidic acid Tetrahedron. 41: 1183-1192. DOI: 10.1016/S0040-4020(01)96519-6 |
0.567 |
|
| 1984 |
Whitman CP, Kenyon GL, Hegeman GD. Affinity labeling of mandelate racemase by S(+)-α-phenylglycidate Federation Proceedings. 43: no. 3435. |
0.424 |
|
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