Irun Cohen - Publications

Weizmann Institute of Science, Rehovot, Israel 
Immunology, Microbiology Biology

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gordin M, Philip H, Zilberberg A, Gidoni M, Margalit R, Clouser C, Adams K, Vigneault F, Cohen IR, Yaari G, Efroni S. Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans. Plos Computational Biology. 17: e1008486. PMID 33465095 DOI: 10.1371/journal.pcbi.1008486  0.48
2020 Liu A, Shi FD, Cohen IR, Castaldo G, Matarese G, Quintana FJ, La Cava A. DNA vaccine encoding heat shock protein 90 protects from murine lupus. Arthritis Research & Therapy. 22: 152. PMID 32571400 DOI: 10.1186/s13075-020-02246-4  0.44
2020 Liu A, Ferretti C, Shi FD, Cohen IR, Quintana FJ, La Cava A. DNA Vaccination with Heat Shock Protein 70 Protects (NZB x NZW)F Mice from Systemic Lupus Erythematosus. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31943822 DOI: 10.1002/art.41202  0.44
2018 Zanin-Zhorov A, Cahalon L, Tal G, Margalit R, Lider O, Cohen IR. Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling. The Journal of Clinical Investigation. PMID 29733295 DOI: 10.1172/JCI121856  0.88
2017 Dishon S, Cohen SJ, Cohen IR, Nussbaum G. Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice. Frontiers in Immunology. 8: 615. PMID 28611775 DOI: 10.3389/fimmu.2017.00615  0.36
2016 Cohen IR, Friedman N, Quintana FJ. T-Cell Vaccination: An Insight Into T-Cell Regulation Translational Neuroimmunology in Multiple Sclerosis: From Disease Mechanisms to Clinical Applications. 457-473. DOI: 10.1016/B978-0-12-801914-6.00031-3  0.44
2015 Swiatczak B, Cohen IR. Gut feelings of safety: tolerance to the microbiota mediated by innate immune receptors. Microbiology and Immunology. 59: 573-85. PMID 26306708 DOI: 10.1111/1348-0421.12318  1
2015 Fattal I, Shental N, Ben-Dor S, Molad Y, Gabrielli A, Pokroy-Shapira E, Oren S, Livneh A, Langevitz P, Zandman-Goddard G, Sarig O, Margalit R, Gafter U, Domany E, Cohen IR. Guanine polynucleotides are self-antigens for human natural autoantibodies and are significantly reduced in the human genome. Immunology. 146: 401-10. PMID 26227667 DOI: 10.1111/imm.12514  1
2015 Madi A, Bransburg-Zabary S, Maayan-Metzger A, Dar G, Ben-Jacob E, Cohen IR. Tumor-associated and disease-associated autoantibody repertoires in healthy colostrum and maternal and newborn cord sera. Journal of Immunology (Baltimore, Md. : 1950). 194: 5272-81. PMID 25917091 DOI: 10.4049/jimmunol.1402771  1
2014 Madi A, Shifrut E, Reich-Zeliger S, Gal H, Best K, Ndifon W, Chain B, Cohen IR, Friedman N. T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity. Genome Research. 24: 1603-12. PMID 25024161 DOI: 10.1101/gr.170753.113  1
2014 Fattal I, Rimer J, Shental N, Molad Y, Gabrielli A, Livneh A, Sarig O, Goldberg I, Gafter U, Domany E, Cohen IR. Pemphigus vulgaris is characterized by low IgG reactivities to specific self-antigens along with high IgG reactivity to desmoglein 3. Immunology. 143: 374-80. PMID 24820664 DOI: 10.1111/imm.12316  1
2014 Raz I, Ziegler AG, Linn T, Schernthaner G, Bonnici F, Distiller LA, Giordano C, Giorgino F, de Vries L, Mauricio D, Procházka V, Wainstein J, Elias D, Avron A, Tamir M, ... ... Cohen IR, et al. Treatment of recent-onset type 1 diabetic patients with DiaPep277: results of a double-blind, placebo-controlled, randomized phase 3 trial. Diabetes Care. 37: 1392-400. PMID 24757230 DOI: 10.2337/dc13-1391  1
2014 Rimer J, Cohen IR, Friedman N. Do all creatures possess an acquired immune system of some sort? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 273-81. PMID 24421210 DOI: 10.1002/bies.201300124  1
2014 Pozzilli P, Raz I, Peled D, Elias D, Avron A, Tamir M, Eren R, Dagan S, Cohen IR. Evaluation of long-term treatment effect in a type 1 diabetes intervention trial: differences after stimulation with glucagon or a mixed meal. Diabetes Care. 37: 1384-91. PMID 24408401 DOI: 10.2337/dc13-1392  1
2014 Fattal I, Shental N, Molad Y, Gabrielli A, Pokroy-Shapira E, Oren S, Livneh A, Langevitz P, Pauzner R, Sarig O, Gafter U, Domany E, Cohen IR. Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA. Immunology. 141: 276-85. PMID 24164500 DOI: 10.1111/imm.12200  1
2013 Zanin-Zhorov A, Cohen IR. Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals. Frontiers in Immunology. 4: 211. PMID 23898332 DOI: 10.3389/fimmu.2013.00211  1
2013 Bransburg-Zabary S, Kenett DY, Dar G, Madi A, Merbl Y, Quintana FJ, Tauber AI, Cohen IR, Ben-Jacob E. Individual and meta-immune networks. Physical Biology. 10: 025003. PMID 23492831 DOI: 10.1088/1478-3975/10/2/025003  1
2013 Mor F, Cohen IR. Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin. Proceedings of the National Academy of Sciences of the United States of America. 110: 2981-6. PMID 23382225 DOI: 10.1073/pnas.1215722110  0.32
2012 Karussis D, Shor H, Yachnin J, Lanxner N, Amiel M, Baruch K, Keren-Zur Y, Haviv O, Filippi M, Petrou P, Hajag S, Vourka-Karussis U, Vaknin-Dembinsky A, Khoury S, Abramsky O, ... ... Cohen IR, et al. T cell vaccination benefits relapsing progressive multiple sclerosis patients: a randomized, double-blind clinical trial. Plos One. 7: e50478. PMID 23272061 DOI: 10.1371/journal.pone.0050478  1
2012 Madi A, Bransburg-Zabary S, Kenett DY, Ben-Jacob E, Cohen IR. The natural autoantibody repertoire in newborns and adults: a current overview. Advances in Experimental Medicine and Biology. 750: 198-212. PMID 22903676 DOI: 10.1007/978-1-4614-3461-0_15  1
2012 Cohen N, Margalit R, Pevsner-Fischer M, Yona S, Jung S, Eisenbach L, Cohen IR. Mouse dendritic cells pulsed with capsular polysaccharide induce resistance to lethal pneumococcal challenge: roles of T cells and B cells. Plos One. 7: e39193. PMID 22723962 DOI: 10.1371/journal.pone.0039193  1
2012 Quintana FJ, Farez MF, Izquierdo G, Lucas M, Cohen IR, Weiner HL. Antigen microarrays identify CNS-produced autoantibodies in RRMS. Neurology. 78: 532-9. PMID 22262743 DOI: 10.1212/WNL.0b013e318247f9f3  1
2012 Pevsner-Fischer M, Levin S, Hammer-Topaz T, Cohen Y, Mor F, Wagemaker G, Nagler A, Cohen IR, Zipori D. Stable changes in mesenchymal stromal cells from multiple myeloma patients revealed through their responses to Toll-like receptor ligands and epidermal growth factor. Stem Cell Reviews. 8: 343-54. PMID 21881833 DOI: 10.1007/s12015-011-9310-2  0.6
2012 Setty Y, Cohen IR, Harel D. Executable modeling of morphogenesis: A Turing-inspired approach Fundamenta Informaticae. 118: 403-417. DOI: 10.3233/FI-2012-722  1
2011 Margel D, Pevsner-Fischer M, Baniel J, Yossepowitch O, Cohen IR. Corrigendum to "Stress Proteins and Cytokines are Urinary Biomarkers for Diagnosis and Staging of Bladder Cancer" [Eur Urol 2011;59:113-9]. European Urology. 59: 670. PMID 27989304 DOI: 10.1016/j.eururo.2010.12.016  0.6
2011 Volovitz I, Marmor Y, Azulay M, Machlenkin A, Goldberger O, Mor F, Slavin S, Ram Z, Cohen IR, Eisenbach L. Split immunity: immune inhibition of rat gliomas by subcutaneous exposure to unmodified live tumor cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 5452-62. PMID 21998458 DOI: 10.4049/jimmunol.1003946  1
2011 Madi A, Kenett DY, Bransburg-Zabary S, Merbl Y, Quintana FJ, Boccaletti S, Tauber AI, Cohen IR, Ben-Jacob E. Analyses of antigen dependency networks unveil immune system reorganization between birth and adulthood. Chaos (Woodbury, N.Y.). 21: 016109. PMID 21456851 DOI: 10.1063/1.3543800  1
2011 Madi A, Kenett DY, Bransburg-Zabary S, Merbl Y, Quintana FJ, Tauber AI, Cohen IR, Ben-Jacob E. Network theory analysis of antibody-antigen reactivity data: the immune trees at birth and adulthood. Plos One. 6: e17445. PMID 21408156 DOI: 10.1371/journal.pone.0017445  1
2011 Quintana FJ, Cohen IR. The HSP60 immune system network. Trends in Immunology. 32: 89-95. PMID 21145789 DOI: 10.1016/  0.44
2011 Margel D, Pevsner-Fischer M, Pesvner-Fischer M, Baniel J, Yossepowitch O, Cohen IR. Stress proteins and cytokines are urinary biomarkers for diagnosis and staging of bladder cancer. European Urology. 59: 113-9. PMID 20970244 DOI: 10.1016/j.eururo.2010.10.008  1
2010 Cohen T, Cohen SJ, Antonovsky N, Cohen IR, Shai Y. HIV-1 gp41 and TCRalpha trans-membrane domains share a motif exploited by the HIV virus to modulate T-cell proliferation. Plos Pathogens. 6: e1001085. PMID 20824090 DOI: 10.1371/journal.ppat.1001085  1
2010 Volovitz I, Marmor Y, Mor F, Flügel A, Odoardi F, Eisenbach L, Cohen IR. T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells. Journal of Autoimmunity. 35: 135-44. PMID 20580204 DOI: 10.1016/j.jaut.2010.05.003  1
2010 Fattal I, Shental N, Mevorach D, Anaya JM, Livneh A, Langevitz P, Zandman-Goddard G, Pauzner R, Lerner M, Blank M, Hincapie ME, Gafter U, Naparstek Y, Shoenfeld Y, Domany E, ... Cohen IR, et al. An antibody profile of systemic lupus erythematosus detected by antigen microarray. Immunology. 130: 337-43. PMID 20201986 DOI: 10.1111/j.1365-2567.2010.03245.x  1
2010 Cohen SJ, Cohen IR, Nussbaum G. IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 212-21. PMID 19949074 DOI: 10.4049/jimmunol.0900296  1
2010 Setty Y, Cohen IR, Harel D. Modeling biology using generic reactive animation Fundamenta Informaticae. 103: 235-246. DOI: 10.3233/FI-2010-327  1
2009 Volovitz I, Mor F, Machlenkin A, Machlenkin A, Goldberger O, Marmor Y, Eisenbach L, Cohen IR, Cohen I. T-cell seeding: neonatal transfer of anti-myelin basic protein T-cell lines renders Fischer rats susceptible later in life to the active induction of experimental autoimmune encephalitis. Immunology. 128: 92-102. PMID 19689739 DOI: 10.1111/j.1365-2567.2009.03074.x  1
2009 Madi A, Hecht I, Bransburg-Zabary S, Merbl Y, Pick A, Zucker-Toledano M, Quintana FJ, Tauber AI, Cohen IR, Ben-Jacob E. Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data. Proceedings of the National Academy of Sciences of the United States of America. 106: 14484-9. PMID 19667184 DOI: 10.1073/pnas.0901528106  1
2009 Cohen-Sfady M, Pevsner-Fischer M, Margalit R, Cohen IR. Heat shock protein 60, via MyD88 innate signaling, protects B cells from apoptosis, spontaneous and induced. Journal of Immunology (Baltimore, Md. : 1950). 183: 890-6. PMID 19561102 DOI: 10.4049/jimmunol.0804238  1
2009 Merbl Y, Itzchak R, Vider-Shalit T, Louzoun Y, Quintana FJ, Vadai E, Eisenbach L, Cohen IR. A systems immunology approach to the host-tumor interaction: large-scale patterns of natural autoantibodies distinguish healthy and tumor-bearing mice. Plos One. 4: e6053. PMID 19557135 DOI: 10.1371/journal.pone.0006053  1
2008 Quintana FJ, Mimran A, Carmi P, Mor F, Cohen IR. HSP60 as a target of anti-ergotypic regulatory T cells. Plos One. 3: e4026. PMID 19107191 DOI: 10.1371/journal.pone.0004026  1
2008 Setty Y, Cohen IR, Dor Y, Harel D. Four-dimensional realistic modeling of pancreatic organogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 20374-9. PMID 19091945 DOI: 10.1073/pnas.0808725105  1
2008 Quintana FJ, Farez MF, Viglietta V, Iglesias AH, Merbl Y, Izquierdo G, Lucas M, Basso AS, Khoury SJ, Lucchinetti CF, Cohen IR, Weiner HL. Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 18889-94. PMID 19028871 DOI: 10.1073/pnas.0806310105  1
2008 Quintana FJ, Solomon A, Cohen IR, Nussbaum G. Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation. Plos One. 3: e3509. PMID 18946502 DOI: 10.1371/journal.pone.0003509  0.44
2008 Quintana FJ, Cohen IR. HSP60 speaks to the immune system in many voices. Novartis Foundation Symposium. 291: 101-11; discussion 1. PMID 18575269  0.44
2008 Quintana FJ, Cohen IR. Regulatory T cells and immune computation. European Journal of Immunology. 38: 903-7. PMID 18395856 DOI: 10.1002/eji.200838143  0.44
2008 Cohen T, Pevsner-Fischer M, Cohen N, Cohen IR, Shai Y. Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor. Biochemistry. 47: 4826-33. PMID 18376816 DOI: 10.1021/bi800100p  1
2008 Cohen N, Stolarsky-Bennun M, Amir-Kroll H, Margalit R, Nussbaum G, Cohen-Sfady M, Pevsner-Fischer M, Fridkin M, Bercovier H, Eisenbach L, Jung S, Cohen IR. Pneumococcal capsular polysaccharide is immunogenic when present on the surface of macrophages and dendritic cells: TLR4 signaling induced by a conjugate vaccine or by lipopolysaccharide is conducive. Journal of Immunology (Baltimore, Md. : 1950). 180: 2409-18. PMID 18250450  1
2007 Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. Response to "Interaction between HIV gp41 fusion peptide and T cell receptor: putting the puzzle pieces back together". Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1635. PMID 29430959 DOI: 10.1096/fj.07-0604ltr  0.44
2007 Zanin-Zhorov A, Tal-Lapidot G, Cahalon L, Cohen-Sfady M, Pevsner-Fischer M, Lider O, Cohen IR. Cutting edge: T cells respond to lipopolysaccharide innately via TLR4 signaling. Journal of Immunology (Baltimore, Md. : 1950). 179: 41-4. PMID 17579019  1
2007 Wucherpfennig KW, Allen PM, Celada F, Cohen IR, De Boer R, Garcia KC, Goldstein B, Greenspan R, Hafler D, Hodgkin P, Huseby ES, Krakauer DC, Nemazee D, Perelson AS, Pinilla C, et al. Polyspecificity of T cell and B cell receptor recognition. Seminars in Immunology. 19: 216-24. PMID 17398114 DOI: 10.1016/j.smim.2007.02.012  1
2007 Shternhall-Ron K, Quintana FJ, Perl S, Meivar-Levy I, Barshack I, Cohen IR, Ferber S. Ectopic PDX-1 expression in liver ameliorates type 1 diabetes. Journal of Autoimmunity. 28: 134-42. PMID 17383157 DOI: 10.1016/j.jaut.2007.02.010  1
2007 Merbl Y, Zucker-Toledano M, Quintana FJ, Cohen IR. Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. The Journal of Clinical Investigation. 117: 712-8. PMID 17332892 DOI: 10.1172/JCI29943  0.44
2007 Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model. Biochemistry. 46: 2317-25. PMID 17288453 DOI: 10.1021/bi061849g  1
2007 Efroni S, Harel D, Cohen IR. Emergent dynamics of thymocyte development and lineage determination. Plos Computational Biology. 3: e13. PMID 17257050 DOI: 10.1371/journal.pcbi.0030013  1
2007 Cohen IR, Harel D. Explaining a complex living system: dynamics, multi-scaling and emergence. Journal of the Royal Society, Interface / the Royal Society. 4: 175-82. PMID 17251153 DOI: 10.1098/rsif.2006.0173  1
2007 Bloch I, Quintana FJ, Gerber D, Cohen T, Cohen IR, Shai Y. T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 393-401. PMID 17185749 DOI: 10.1096/fj.06-7061com  1
2007 Brent L, Cohen IR, Doherty PC, Feldmann M, Matzinger P, Ghost Lab, Holgate ST, Lachmann P, Mitchison NA, Nossal G, Rose NR, Zinkernagel R. Crystal-ball gazing--the future of immunological research viewed from the cutting edge. Clinical and Experimental Immunology. 147: 1-10. PMID 17177957 DOI: 10.1111/j.1365-2249.2006.03234.x  1
2007 Raz I, Avron A, Tamir M, Metzger M, Symer L, Eldor R, Cohen IR, Elias D. Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomized, double-blind, phase II trial. Diabetes/Metabolism Research and Reviews. 23: 292-8. PMID 17124720 DOI: 10.1002/dmrr.712  1
2007 Pevsner-Fischer M, Morad V, Cohen-Sfady M, Rousso-Noori L, Zanin-Zhorov A, Cohen S, Cohen IR, Zipori D. Toll-like receptors and their ligands control mesenchymal stem cell functions. Blood. 109: 1422-32. PMID 17038530 DOI: 10.1182/blood-2006-06-028704  1
2007 Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. Response to "Interaction between HIV gp41 fusion peptide and T cell receptor: Putting the puzzle pieces back together" [2] Faseb Journal. 21: 1635. DOI: 10.1096/fj.07-0604ltr  1
2006 Nussbaum G, Zanin-Zhorov A, Quintana F, Lider O, Cohen IR. Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis. International Immunology. 18: 1413-9. PMID 16893923 DOI: 10.1093/intimm/dxl074  1
2006 Quintana FJ, Zaltzman R, Fernandez-Montesinos R, Herrera JL, Gozes I, Cohen IR, Pozo D. NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function. Annals of the New York Academy of Sciences. 1070: 500-6. PMID 16888216 DOI: 10.1196/annals.1317.069  1
2006 Zanin-Zhorov A, Cahalon L, Tal G, Margalit R, Lider O, Cohen IR. Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. The Journal of Clinical Investigation. 116: 2022-32. PMID 16767222 DOI: 10.1172/JCI28423  1
2006 Mor F, Cohen IR. How special is a pathogenic CNS autoantigen? Immunization to many CNS self-antigens does not induce autoimmune disease. Journal of Neuroimmunology. 174: 3-11. PMID 16427143 DOI: 10.1016/j.jneuroim.2005.12.003  0.32
2005 Cohen-Sfady M, Nussbaum G, Pevsner-Fischer M, Mor F, Carmi P, Zanin-Zhorov A, Lider O, Cohen IR. Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway. Journal of Immunology (Baltimore, Md. : 1950). 175: 3594-602. PMID 16148103  1
2005 Mor F, Izak M, Cohen IR. Identification of aldolase as a target antigen in Alzheimer's disease. Journal of Immunology (Baltimore, Md. : 1950). 175: 3439-45. PMID 16116239  0.32
2005 Quintana FJ, Cohen IR. Heat shock proteins as endogenous adjuvants in sterile and septic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 175: 2777-82. PMID 16116161  0.44
2005 Mimran A, Cohen IR. Regulatory T cells in autoimmune diseases: anti-ergotypic T cells. International Reviews of Immunology. 24: 159-79. PMID 16036372 DOI: 10.1080/08830180590934949  1
2005 Quintana FJ, Gerber D, Kent SC, Cohen IR, Shai Y. HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation. The Journal of Clinical Investigation. 115: 2149-58. PMID 16007266 DOI: 10.1172/JCI23956  1
2005 Zanin-Zhorov A, Tal G, Shivtiel S, Cohen M, Lapidot T, Nussbaum G, Margalit R, Cohen IR, Lider O. Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation. Journal of Immunology (Baltimore, Md. : 1950). 175: 276-85. PMID 15972659  1
2005 Quintana FJ, Cohen IR. DNA vaccines coding for heat-shock proteins (HSPs): tools for the activation of HSP-specific regulatory T cells. Expert Opinion On Biological Therapy. 5: 545-54. PMID 15934832 DOI: 10.1517/14712598.5.4.545  0.44
2005 Mimran A, Mor F, Quintana FJ, Cohen IR. Anti-ergotypic T cells in naïve rats. Journal of Autoimmunity. 24: 191-201. PMID 15848041 DOI: 10.1016/j.jaut.2004.12.002  1
2005 Gerber D, Quintana FJ, Bloch I, Cohen IR, Shai Y. D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1190-2. PMID 15837719 DOI: 10.1096/fj.04-3498fje  1
2005 Zanin-Zhorov A, Bruck R, Tal G, Oren S, Aeed H, Hershkoviz R, Cohen IR, Lider O. Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines. Journal of Immunology (Baltimore, Md. : 1950). 174: 3227-36. PMID 15749853  1
2005 Efroni S, Harel D, Cohen Ir. 17 A theory for complex systems: reactive animation Studies in Multidisciplinarity. 3: 309-324. DOI: 10.1016/S1571-0831(06)80021-3  1
2004 Quintana FJ, Carmi P, Mor F, Cohen IR. Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein. Arthritis and Rheumatism. 50: 3712-20. PMID 15529360 DOI: 10.1002/art.20635  0.44
2004 Cohen IR, Quintana FJ, Mimran A. Tregs in T cell vaccination: exploring the regulation of regulation. The Journal of Clinical Investigation. 114: 1227-32. PMID 15520852 DOI: 10.1172/JCI23396  1
2004 Herkel J, Kam N, Erez N, Mimran A, Heifetz A, Eisenstein M, Rotter V, Cohen IR. Monoclonal antibody to a DNA-binding domain of p53 mimics charge structure of DNA: anti-idiotypes to the anti-p53 antibody are anti-DNA. European Journal of Immunology. 34: 3623-32. PMID 15495163 DOI: 10.1002/eji.200425371  1
2004 Achiron A, Lavie G, Kishner I, Stern Y, Sarova-Pinhas I, Ben-Aharon T, Barak Y, Raz H, Lavie M, Barliya T, Faibel M, Cohen IR, Mandel M. T cell vaccination in multiple sclerosis relapsing-remitting nonresponders patients. Clinical Immunology (Orlando, Fla.). 113: 155-60. PMID 15451472 DOI: 10.1016/j.clim.2004.06.004  1
2004 Quintana FJ, Hagedorn PH, Elizur G, Merbl Y, Domany E, Cohen IR. Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes. Proceedings of the National Academy of Sciences of the United States of America. 101: 14615-21. PMID 15308778 DOI: 10.1073/pnas.0404848101  0.44
2004 Montero E, Nussbaum G, Kaye JF, Perez R, Lage A, Ben-Nun A, Cohen IR. Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies. Journal of Autoimmunity. 23: 1-7. PMID 15236747 DOI: 10.1016/j.jaut.2004.05.001  0.36
2004 Quintana FJ, Cohen IR. The natural autoantibody repertoire and autoimmune disease. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 58: 276-81. PMID 15194162 DOI: 10.1016/j.biopha.2004.04.011  0.44
2004 Quintana FJ, Buzas E, Prohászka Z, Bíró A, Kocsis J, Füst G, Falus A, Cohen IR. Knock-out of the histidine decarboxylase gene modifies the repertoire of natural autoantibodies. Journal of Autoimmunity. 22: 297-305. PMID 15120753 DOI: 10.1016/j.jaut.2004.03.003  0.44
2004 Mimran A, Mor F, Carmi P, Quintana FJ, Rotter V, Cohen IR. DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response. The Journal of Clinical Investigation. 113: 924-32. PMID 15067325 DOI: 10.1172/JCI17772  1
2004 Cohen IR, Hershberg U, Solomon S. Antigen-receptor degeneracy and immunological paradigms. Molecular Immunology. 40: 993-6. PMID 15036901 DOI: 10.1016/j.molimm.2003.11.020  1
2004 Mor F, Quintana FJ, Cohen IR. Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization. Journal of Immunology (Baltimore, Md. : 1950). 172: 4618-23. PMID 15034080  0.44
2004 Hecht I, Hershkoviz R, Shivtiel S, Lapidot T, Cohen IR, Lider O, Cahalon L. Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling. Journal of Leukocyte Biology. 75: 1139-46. PMID 15020655 DOI: 10.1189/jlb.1203659  1
2003 Efroni S, Harel D, Cohen IR. Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation. Genome Research. 13: 2485-97. PMID 14597657 DOI: 10.1101/gr.1215303  1
2003 Quintana FJ, Carmi P, Mor F, Cohen IR. DNA fragments of the human 60-kDa heat shock protein (HSP60) vaccinate against adjuvant arthritis: identification of a regulatory HSP60 peptide. Journal of Immunology (Baltimore, Md. : 1950). 171: 3533-41. PMID 14500649  0.44
2003 Quintana FJ, Getz G, Hed G, Domany E, Cohen IR. Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity. Journal of Autoimmunity. 21: 65-75. PMID 12892737  0.44
2003 Zanin-Zhorov A, Nussbaum G, Franitza S, Cohen IR, Lider O. T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1567-9. PMID 12824285 DOI: 10.1096/fj.02-1139fje  1
2003 Amir-Kroll H, Nussbaum G, Cohen IR. Proteins and their derived peptides as carriers in a conjugate vaccine for Streptococcus pneumoniae: self-heat shock protein 60 and tetanus toxoid. Journal of Immunology (Baltimore, Md. : 1950). 170: 6165-71. PMID 12794147  0.36
2003 Tal Y, Souan L, Cohen IR, Meiner Z, Taraboulos A, Mor F. Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice. Journal of Neuroscience Research. 71: 286-90. PMID 12503092 DOI: 10.1002/jnr.10474  0.32
2003 Quintana FJ, Pitashny M, Cohen IR. Experimental autoimmune myasthenia gravis in naive non-obese diabetic (NOD/LtJ) mice: susceptibility associated with natural IgG antibodies to the acetylcholine receptor. International Immunology. 15: 11-6. PMID 12502721  0.44
2003 Mor F, Quintana F, Mimran A, Cohen IR. Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein. Journal of Immunology (Baltimore, Md. : 1950). 170: 628-34. PMID 12496452  1
2002 Gonzalez G, Montero E, Leon K, Cohen IR, Lage A. Autoimmunization to epidermal growth factor, a component of the immunological homunculus. Autoimmunity Reviews. 1: 89-95. PMID 12849064 DOI: 10.1016/S1568-9972(01)00015-5  1
2002 Herkel J, Modrow JP, Bamberger S, Kanzler S, Rotter V, Cohen IR, Lohse AW. Prevalence of autoantibodies to the p53 protein in autoimmune hepatitis. Autoimmunity. 35: 493-6. PMID 12765474 DOI: 10.1080/0891693021000054075  1
2002 Quintana FJ, Carmi P, Cohen IR. DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes. Journal of Immunology (Baltimore, Md. : 1950). 169: 6030-5. PMID 12421990  0.44
2002 Quintana FJ, Carmi P, Mor F, Cohen IR. Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60. Journal of Immunology (Baltimore, Md. : 1950). 169: 3422-8. PMID 12218165  0.44
2002 Mor F, Cohen IR. Propagation of lewis rat encephalitogenic T cell lines: T-cell-growth-factor is superior to recombinant IL-2. Journal of Neuroimmunology. 123: 76-82. PMID 11880152  0.32
2002 Mor F, Weinberger A, Cohen IR. Identification of alpha-tropomyosin as a target self-antigen in Behçet's syndrome. European Journal of Immunology. 32: 356-65. PMID 11807775 DOI: 10.1002/1521-4141(200202)32:2<356::AID-IMMU356>3.0.CO;2-9  0.32
2001 Milyavsky M, Mimran A, Senderovich S, Zurer I, Erez N, Shats I, Goldfinger N, Cohen I, Rotter V. Activation of p53 protein by telomeric (TTAGGG)n repeats. Nucleic Acids Research. 29: 5207-15. PMID 11812854  1
2001 Raz I, Elias D, Avron A, Tamir M, Metzger M, Cohen IR. Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet (London, England). 358: 1749-53. PMID 11734230 DOI: 10.1016/S0140-6736(01)06801-5  1
2001 Herkel J, Mimran A, Erez N, Kam N, Lohse AW, Märker-Hermann E, Rotter V, Cohen IR. Autoimmunity to the p53 protein is a feature of systemic lupus erythematosus (SLE) related to anti-DNA antibodies. Journal of Autoimmunity. 17: 63-9. PMID 11488638 DOI: 10.1006/jaut.2001.0518  1
2001 Chowers Y, Lider O, Schor H, Barshack I, Tal R, Ariel A, Bar-Meir S, Cohen IR, Cahalon L. Disaccharides derived from heparin or heparan sulfate regulate IL-8 and IL-1 beta secretion by intestinal epithelial cells. Gastroenterology. 120: 449-59. PMID 11159885 DOI: 10.1053/gast.2001.21202  1
2000 Moalem G, Gdalyahu A, Shani Y, Otten U, Lazarovici P, Cohen IR, Schwartz M. Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity. Journal of Autoimmunity. 15: 331-45. PMID 11040074 DOI: 10.1006/jaut.2000.0441  1
2000 Kipnis J, Yoles E, Porat Z, Cohen A, Mor F, Sela M, Cohen IR, Schwartz M. T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: possible therapy for optic neuropathies. Proceedings of the National Academy of Sciences of the United States of America. 97: 7446-51. PMID 10861010 DOI: 10.1073/pnas.97.13.7446  1
2000 Herkel J, Erez-Alon N, Mimran A, Wolkowicz R, Harmelin A, Ruiz P, Rotter V, Cohen IR. Systemic lupus erythematosus in mice, spontaneous and induced, is associated with autoimmunity to the C-terminal domain of p53 that recognizes damaged DNA. European Journal of Immunology. 30: 977-84. PMID 10760784 DOI: 10.1002/(SICI)1521-4141(200004)30:4<977::AID-IMMU977>3.0.CO;2-A  1
2000 Hershkoviz R, Schor H, Ariel A, Hecht I, Cohen IR, Lider O, Cahalon L. Disaccharides generated from heparan sulphate or heparin modulate chemokine-induced T-cell adhesion to extracellular matrix. Immunology. 99: 87-93. PMID 10651945 DOI: 10.1046/j.1365-2567.2000.00931.x  1
1999 Tikochinski Y, Elias D, Steeg C, Marcus H, Kantorowitz M, Reshef T, Ablamunits V, Cohen IR, Friedmann A. A shared TCR CDR3 sequence in NOD mouse autoimmune diabetes International Immunology. 11: 951-956. PMID 10360969 DOI: 10.1093/intimm/11.6.951  1
1999 Rechter M, Lider O, Cahalon L, Baharav E, Dekel M, Seigel D, Vlodavsky I, Aingorn H, Cohen IR, Shoseyov O. A cellulose-binding domain-fused recombinant human T cell connective tissue-activating peptide-III manifests heparanase activity Biochemical and Biophysical Research Communications. 255: 657-662. PMID 10049766 DOI: 10.1006/bbrc.1999.0181  1
1999 Ablamunits V, Elias D, Cohen IR. The pathogenicity of islet-infiltrating lymphocytes in the non-obese diabetic (NOD) mouse Clinical and Experimental Immunology. 115: 260-267. PMID 9933451 DOI: 10.1046/j.1365-2249.1999.00802.x  1
1998 Ruiz PJ, Wolkowicz R, Waisman A, Hirschberg DL, Carmi P, Erez N, Garren H, Herkel J, Karpuj M, Steinman L, Rotter V, Cohen IR. Idiotypic immunization induces immunity to mutated p53 and tumor rejection. Nature Medicine. 4: 710-2. PMID 9623981 DOI: 10.1038/nm0698-710  1
1997 Cahalon L, Lider O, Schor H, Avron A, Gilat D, Hershkoviz R, Margalit R, Eshel A, Shoseyev O, Cohen IR. Heparin disaccharides inhibit tumor necrosis factor-alpha production by macrophages and arrest immune inflammation in rodents. International Immunology. 9: 1517-22. PMID 9352356 DOI: 10.1093/intimm/9.10.1517  1
1997 Bockova J, Elias D, Cohen IR. Treatment of NOD diabetes with a novel peptide of the hsp60 molecule induces Th2-type antibodies Journal of Autoimmunity. 10: 323-329. PMID 9237795 DOI: 10.1006/jaut.1997.0150  1
1997 Reizis B, Schild H, Stefanović S, Mor F, Rammensee H, Cohen IR. Peptide binding motifs of the MHC class I molecules (RT1.Al) of the Lewis rat. Immunogenetics. 45: 278-9. PMID 9002449 DOI: 10.1007/s002510050204  0.32
1996 Reizis B, Mor F, Eisenstein M, Schild H, Stefanoviç S, Rammensee HG, Cohen IR. The peptide binding specificity of the MHC class II I-A molecule of the Lewis rat, RT1.BI. International Immunology. 8: 1825-32. PMID 8982766 DOI: 10.1093/intimm/8.12.1825  0.32
1996 Elias D, Cohen IR. The hsp60 peptide p277 arrests the autoimmune diabetes induced by the toxin streptozotocin Diabetes. 45: 1168-1172. PMID 8772717 DOI: 10.2337/diab.45.9.1168  1
1996 Birk OS, Elias D, Weiss AS, Rosen A, Van-Der Zee R, Walker MD, Cohen IR. NOD mouse diabetes: The ubiquitous mouse hsp60 is a β-cell target antigen of autoimmune T cells Journal of Autoimmunity. 9: 159-166. PMID 8738959 DOI: 10.1006/jaut.1996.0019  1
1996 Waisman A, Ruiz PJ, Hirschberg DL, Gelman A, Oksenberg JR, Brocke S, Mor F, Cohen IR, Steinman L. Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nature Medicine. 2: 899-905. PMID 8705860 DOI: 10.1038/nm0896-899  1
1996 Birk OS, Douek DC, Elias D, Takacs K, Dewchand H, Gur SL, Walker MD, Van Der Zee R, Cohen IR, Altmann DM. A role of Hsp60 in autoimmune diabetes: Analysis in a transgenic model Proceedings of the National Academy of Sciences of the United States of America. 93: 1032-1037. PMID 8577709 DOI: 10.1073/pnas.93.3.1032  1
1995 Segel LA, Jäger E, Elias D, Cohen IR. A quantitative model of autoimmune disease and T-cell vaccination: does more mean less? Immunology Today. 16: 80-84. PMID 7888071 DOI: 10.1016/0167-5699(95)80093-X  1
1995 Elias D, Cohen IR. Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277 Diabetes. 44: 1132-1138. PMID 7657040 DOI: 10.2337/diab.44.9.1132  1
1994 Achiron A, Margalit R, Hershkoviz R, Markovits D, Reshef T, Melamed E, Cohen IR, Lider O. Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor alpha secretion. The Journal of Clinical Investigation. 93: 600-5. PMID 8113397 DOI: 10.1172/JCI117012  0.6
1994 Achiron A, Gilad R, Margalit R, Gabbay U, Sarova-Pinhas I, Cohen IR, Melamed E, Lider O, Noy S, Ziv I. Intravenous gammaglobulin treatment in multiple sclerosis and experimental autoimmune encephalomyelitis: delineation of usage and mode of action. Journal of Neurology, Neurosurgery, and Psychiatry. 57: 57-61. PMID 7964856 DOI: 10.1136/jnnp.57.Suppl.57  1
1994 Elias D, Cohen IR. Peptide therapy for diabetes in NOD mice The Lancet. 343: 704-706. PMID 7907681 DOI: 10.1016/S0140-6736(94)91582-2  1
1994 Cohen IR. Treatment of autoimmune disease: To activate or to deactivate? Chemical Immunology. 60: 150-160. PMID 7857526  1
1992 Cohen IR. The cognitive principle challenges clonal selection Immunology Today. 13: 441-444. PMID 1476598  1
1991 Feige U, Cohen IR. The 65-kDa heat-shock protein in the pathogenesis, prevention and therapy of autoimmune arthritis and diabetes mellitus in rats and mice Springer Seminars in Immunopathology. 13: 99-113. PMID 1776121 DOI: 10.1007/BF01225281  1
1991 Cohen IR. T-cell vaccination in immunological disease Journal of Internal Medicine. 230: 471-477. PMID 1748855  1
1991 Cohen IR. The aging paradox and autoimmune disease by E. Talor and N.R. Rose Autoimmunity. 8: 253. DOI: 10.3109/08916939108997114  1
1990 Elias D, Bone AJ, Baird JD, Cooke A, Cohen IR. Insulin-mimicking anti-idiotypic antibodies in development of spontaneous autoimmune diabetes in BB/E rats. Diabetes. 39: 1467-71. PMID 2245874 DOI: 10.2337/diab.39.12.1467  1
1989 Cohen IR. An eclectic summary of the symposium on autoimmunity Immunology Today. 10: 394-396. PMID 2619875  1
1989 Cohen IR, Elias D, Rapoport M, Shechter Y. Production and properties of anti-idiotypic antibodies that recognize insulin receptor Methods in Enzymology. 178: 300-308. PMID 2513465 DOI: 10.1016/0076-6879(89)78022-8  1
1989 Cohen IR. T-cell vaccination against autoimmune disease Hospital Practice. 24: 57-64. PMID 2493021  1
1988 Elias D, Rapoport M, Cohen IR, Shechter Y. Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with β-adrenergic agonists Journal of Clinical Investigation. 81: 1979-1985. PMID 3290258 DOI: 10.1172/JCI113546  1
1987 Elias D, Cohen IR, Schechter Y, Spirer Z, Golander A. Antibodies to insulin receptor followed by anti-idiotype. Antibodies to insulin in child with hypoglycemia. Diabetes. 36: 348-54. PMID 3803741 DOI: 10.2337/diab.36.3.348  1
1987 Altmlann DM, Lider O, Douek DC, Cohen IR. Activation of specific T call lines by the antigens avidin and myelin basic protein in the absence of antigen-presenting cells European Journal of Immunology. 17: 1635-1640. PMID 2445586 DOI: 10.1002/eji.1830171117  1
1986 Cohen IR. Regulation of autoimmune disease: Physiological and therapeutic Immunological Reviews. 5-21. PMID 2948901  1
1984 Sela BA, Offner H, Konat G, Lev-Ram V, Cohen O, Cohen IR. Immunological expression of gangliosides in multiple sclerosis and in a demyelinating model disease in rabbits. Advances in Experimental Medicine and Biology. 174: 441-53. PMID 6611045 DOI: 10.1007/978-1-4684-1200-0_37  1
1983 Shechter Y, Elias D, Maron R, Cohen IR. Mice immunized to insulin develop antibody to the insulin receptor Journal of Cellular Biochemistry. 21: 179-185. PMID 6350327 DOI: 10.1002/jcb.240210208  1
1983 Maron R, Elias D, de Jongh BM, Bruining GJ, van Rood JJ, Shechter Y, Cohen IR. Autoantibodies to the insulin receptor in juvenile onset insulin-dependent diabetes. Nature. 303: 817-8. PMID 6346102 DOI: 10.1038/303817a0  1
1983 Yarom Y, Naparstek Y, Lev-Ram V, Holoshitz J, Ben-Nun A, Cohen IR. Immunospecific inhibition of nerve conduction by T lymphocytes reactive to basic protein of myelin. Nature. 303: 246-7. PMID 6188958 DOI: 10.1038/303246a0  1
1982 Shechter Y, Maron R, Elias D, Cohen IR. Autoantibodies to insulin receptor spontaneously develop as anti-idiotypes in mice immunized with insulin Science. 216: 542-545. PMID 7041258 DOI: 10.1126/science.7041258  1
1979 Cohen IR, Talmon J, Lev-Ram V, Ben-Nun A. Immune response genes have a variable influence on the selection of antigenic foreign and self determinants of insulin. Proceedings of the National Academy of Sciences of the United States of America. 76: 4066-70. PMID 91175 DOI: 10.1073/pnas.76.8.4066  1
1978 Steinman L, Tzehoval E, Cohen IR, Segal S, Glickman E. Sequential interaction of macrophages, initiator T lymphocytes and recruited T lymphocytes in a cell-mediated immune response to soluble antigen European Journal of Immunology. 8: 29-34. PMID 76565 DOI: 10.1002/eji.1830080107  1
1976 Altman A, Cohen IR. Differentiation of cytotoxic T lymphocytes enhanced by T cell factors produced during mixed lymphocyte interactions Advances in Experimental Medicine and Biology. 66: 289-294. PMID 1083639 DOI: 10.1007/978-1-4613-4355-4_43  1
1975 Altman A, Cohen IR. Cell free media of mixed lymphocyte cultures augmenting sensitization in vitro of mouse T lymphocytes against allogeneic fibroblasts European Journal of Immunology. 5: 437-444. PMID 135686 DOI: 10.1002/eji.1830050702  1
1975 Altman A, Cohen IR. Heterogeneity in the development of cytotoxic T lymphocytes in vitro revealed by sensitivity to hydrocortisone Journal of Experimental Medicine. 142: 790-795. PMID 126272 DOI: 10.1084/jem.142.3.790  1
1974 Altman A, Cohen IR. The nonspecific helper effect of mixed lymphocyte reactions on the induction of T cell mediated immunity in vitro European Journal of Immunology. 4: 577-580. PMID 4278331 DOI: 10.1002/eji.1830040811  1
1974 Orgad S, Cohen IR. Autoimmune encephalomyelitis: activation of thymus lymphocytes against syngeneic brain antigens in vitro. Science (New York, N.Y.). 183: 1083-5. PMID 4130125 DOI: 10.1126/science.183.4129.1083  1
1973 Treves AJ, Cohen IR. Recruitment of effector T lymphocytes against a tumor allograft by T lymphocytes sensitized in vitro. Journal of the National Cancer Institute. 51: 1919-25. PMID 4543604 DOI: 10.1093/jnci/51.6.1919  1
1973 Cohen IR. The recruitment of specific effector lymphocytes by antigen-reactive lymphocytes in cell-mediated autosensitization and allosensitization reactions Cellular Immunology. 8: 209-220. PMID 4125285 DOI: 10.1016/0008-8749(73)90111-1  1
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