John H. Brumell - Publications

Medical Science University of Toronto, Toronto, ON, Canada 
Cell Biology, Microbiology Biology

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rojas Márquez JD, Li T, McCluggage ARR, Tan JMJ, Muise A, Higgins DE, Brumell JH. Cutting Edge: NOX2 NADPH Oxidase Controls Infection by an Intracellular Bacterial Pathogen through Limiting the Type 1 IFN Response. Journal of Immunology (Baltimore, Md. : 1950). PMID 33288542 DOI: 10.4049/jimmunol.2000694  0.36
2018 Coyaud E, Ranadheera C, Cheng D, Gonçalves J, Dyakov BJA, Laurent EMN, St-Germain J, Pelletier L, Gingras AC, Brumell JH, Kim PK, Safronetz D, Raught B. Global Interactomics Uncovers Extensive Organellar Targeting by Zika Virus. Molecular & Cellular Proteomics : McP. 17: 2242-2255. PMID 33503773 DOI: 10.1074/mcp.TIR118.000800  0.48
2018 Tan JMJ, Mellouk N, Osborne SE, Ammendolia DA, Dyer DN, Li R, Brunen D, van Rijn JM, Huang J, Czuczman MA, Cemma MA, Won AM, Yip CM, Xavier RJ, MacDuff DA, ... ... Brumell JH, et al. An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread. Nature Microbiology. 3: 1472-1485. PMID 30478389 DOI: 10.1038/s41564-018-0293-5  0.64
2018 Coyaud E, Ranadheera C, Cheng DT, Goncalves J, Dyakov B, Laurent E, St-Germain JR, Pelletier L, Gingras AC, Brumell JH, Kim PK, Safronetz D, Raught B. Global interactomics uncovers extensive organellar targeting by Zika virus. Molecular & Cellular Proteomics : McP. PMID 30037810 DOI: 10.1074/mcp.TIR118.000800  0.48
2018 Ghosh P, Halvorsen EM, Ammendolia DA, Mor-Vaknin N, O'Riordan MXD, Brumell JH, Markovitz DM, Higgins DE. Invasion of the Brain byIs Mediated by InlF and Host Cell Vimentin. Mbio. 9. PMID 29487235 DOI: 10.1128/mBio.00160-18  0.36
2017 Law KB, Bronte-Tinkew D, Di Pietro E, Snowden A, Jones RO, Moser A, Brumell JH, Braverman N, Kim PK. The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders. Autophagy. 13: 868-884. PMID 28521612 DOI: 10.1080/15548627.2017.1291470  0.48
2017 Hua R, Cheng D, Coyaud É, Freeman S, Di Pietro E, Wang Y, Vissa A, Yip CM, Fairn GD, Braverman N, Brumell JH, Trimble WS, Raught B, Kim PK. VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis. The Journal of Cell Biology. PMID 28108526 DOI: 10.1083/jcb.201608128  0.48
2016 Osborne SE, Sit B, Shaker A, Currie E, Tan JM, van Rijn J, Higgins DE, Brumell JH. Type I Interferon Promotes Cell-to-Cell Spread of Listeria monocytogenes. Cellular Microbiology. PMID 27582004 DOI: 10.1111/cmi.12660  0.36
2016 Cemma M, Grinstein S, Brumell JH. Autophagy Proteins are not Universally Required for Phagosome Maturation. Autophagy. 0. PMID 27310610 DOI: 10.1080/15548627.2016.1191724  0.48
2016 Dolma S, Selvadurai HJ, Lan X, Lee L, Kushida M, Voisin V, Whetstone H, So M, Aviv T, Park N, Zhu X, Xu C, Head R, Rowland KJ, Bernstein M, ... ... Brumell JH, et al. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 29: 859-873. PMID 27300435 DOI: 10.1016/j.ccell.2016.05.002  1
2016 Li Q, Lee CH, Peters LA, Mastropaolo LA, Thoeni C, Elkadri A, Schwerd T, Zhu J, Zhang B, Zhao Y, Hao K, Dinarzo A, Hoffman G, Kidd BA, Murchie R, ... ... Brumell JH, et al. Variants in TRIM22 that Affect NOD2 Signaling Are Associated With Very Early Onset Inflammatory Bowel Disease. Gastroenterology. PMID 26836588 DOI: 10.1053/j.gastro.2016.01.031  1
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Brumell JH, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.48
2015 Hayes P, Dhillon S, O'Neill K, Thoeni C, Hui KY, Elkadri A, Guo CH, Kovacic L, Aviello G, Alvarez LA, Griffiths AM, Snapper SB, Brant SR, Doroshow JH, Silverberg MS, ... ... Brumell JH, et al. Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology. 1: 489-502. PMID 26301257 DOI: 10.1016/j.jcmgh.2015.06.005  1
2015 D'Costa VM, Braun V, Landekic M, Shi R, Proteau A, McDonald L, Cygler M, Grinstein S, Brumell JH. Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports. 12: 1508-18. PMID 26299973 DOI: 10.1016/j.celrep.2015.07.063  1
2015 Sit B, Crowley SM, Bhullar K, Lai CC, Tang C, Hooda Y, Calmettes C, Khambati H, Ma C, Brumell JH, Schryvers AB, Vallance BA, Moraes TF. Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathogens. 11: e1005107. PMID 26295949 DOI: 10.1371/journal.ppat.1005107  1
2015 Hu Y, Carraro-Lacroix LR, Wang A, Owen C, Bajenova E, Corey PN, Brumell JH, Voronov I. Lysosomal pH Plays a Key Role in Regulation of mTOR Activity in Osteoclasts. Journal of Cellular Biochemistry. PMID 26212375 DOI: 10.1002/jcb.25287  1
2015 Cemma M, Lam GY, Stöckli M, Higgins DE, Brumell JH. Strain-Specific Interactions of Listeria monocytogenes with the Autophagy System in Host Cells. Plos One. 10: e0125856. PMID 25970638 DOI: 10.1371/journal.pone.0125856  1
2015 Fattouh R, Kwon H, Czuczman MA, Copeland JW, Pelletier L, Quinlan ME, Muise AM, Higgins DE, Brumell JH. The diaphanous-related formins promote protrusion formation and cell-to-cell spread of Listeria monocytogenes. The Journal of Infectious Diseases. 211: 1185-95. PMID 25281757 DOI: 10.1093/infdis/jiu546  1
2014 Dhillon SS, Fattouh R, Elkadri A, Xu W, Murchie R, Walters T, Guo C, Mack D, Huynh HQ, Baksh S, Silverberg MS, Griffiths AM, Snapper SB, Brumell JH, Muise AM. Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease. Gastroenterology. 147: 680-689.e2. PMID 24931457 DOI: 10.1053/j.gastro.2014.06.005  1
2014 Truong D, Copeland JW, Brumell JH. Bacterial subversion of host cytoskeletal machinery: hijacking formins and the Arp2/3 complex. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 687-96. PMID 24849003 DOI: 10.1002/bies.201400038  1
2014 Costford SR, Castro-Alves J, Chan KL, Bailey LJ, Woo M, Belsham DD, Brumell JH, Klip A. Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver. American Journal of Physiology. Endocrinology and Metabolism. 306: E1341-53. PMID 24760992 DOI: 10.1152/ajpendo.00089.2014  1
2014 Czuczman MA, Fattouh R, van Rijn JM, Canadien V, Osborne S, Muise AM, Kuchroo VK, Higgins DE, Brumell JH. Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread. Nature. 509: 230-4. PMID 24739967 DOI: 10.1038/nature13168  1
2014 Zhang L, Chen X, Sharma P, Moon M, Sheftel AD, Dawood F, Nghiem MP, Wu J, Li RK, Gramolini AO, Sorensen PH, Penninger JM, Brumell JH, Liu PP. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nature Communications. 5: 3430. PMID 24614889 DOI: 10.1038/ncomms4430  1
2014 Dhillon SS, Mastropaolo LA, Murchie R, Griffiths C, Thöni C, Elkadri A, Xu W, Mack A, Walters T, Guo C, Mack D, Huynh H, Baksh S, Silverberg MS, Brumell JH, et al. Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease. Clinical and Translational Gastroenterology. 5: e46. PMID 24430113 DOI: 10.1038/ctg.2013.17  1
2014 Avitzur Y, Guo C, Mastropaolo LA, Bahrami E, Chen H, Zhao Z, Elkadri A, Dhillon S, Murchie R, Fattouh R, Huynh H, Walker JL, Wales PW, Cutz E, Kakuta Y, ... ... Brumell JH, et al. Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease. Gastroenterology. 146: 1028-39. PMID 24417819 DOI: 10.1053/j.gastro.2014.01.015  1
2014 Huang J, Brumell JH. Bacteria-autophagy interplay: a battle for survival. Nature Reviews. Microbiology. 12: 101-14. PMID 24384599 DOI: 10.1038/nrmicro3160  1
2013 Roppenser B, Kwon H, Canadien V, Xu R, Devreotes PN, Grinstein S, Brumell JH. Multiple host kinases contribute to Akt activation during Salmonella infection. Plos One. 8: e71015. PMID 23990921 DOI: 10.1371/journal.pone.0071015  1
2013 Truong D, Brabant D, Bashkurov M, Wan LC, Braun V, Heo WD, Meyer T, Pelletier L, Copeland J, Brumell JH. Formin-mediated actin polymerization promotes Salmonella invasion. Cellular Microbiology. 15: 2051-63. PMID 23869992 DOI: 10.1111/cmi.12173  1
2013 Chaturvedi S, Yuen DA, Bajwa A, Huang YW, Sokollik C, Huang L, Lam GY, Tole S, Liu GY, Pan J, Chan L, Sokolskyy Y, Puthia M, Godaly G, John R, ... ... Brumell JH, et al. Slit2 prevents neutrophil recruitment and renal ischemia-reperfusion injury. Journal of the American Society of Nephrology : Jasn. 24: 1274-87. PMID 23766538 DOI: 10.1681/ASN.2012090890  1
2013 Hu P, Muise AM, Xing X, Brumell JH, Silverberg MS, Xu W. Association between a multi-locus genetic risk score and inflammatory bowel disease. Bioinformatics and Biology Insights. 7: 143-52. PMID 23761965 DOI: 10.4137/BBI.S11601  1
2013 Fattouh R, Guo CH, Lam GY, Gareau MG, Ngan BY, Glogauer M, Muise AM, Brumell JH. Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection. Plos One. 8: e61629. PMID 23613889 DOI: 10.1371/journal.pone.0061629  1
2013 Lam GY, Cemma M, Muise AM, Higgins DE, Brumell JH. Host and bacterial factors that regulate LC3 recruitment to Listeria monocytogenes during the early stages of macrophage infection. Autophagy. 9: 985-95. PMID 23584039 DOI: 10.4161/auto.24406  1
2013 Cemma M, Brumell JH. Immunology. Bacterial escape artists set afire. Science (New York, N.Y.). 339: 912-3. PMID 23430642 DOI: 10.1126/science.1235639  1
2013 Tyler AD, Milgrom R, Stempak JM, Xu W, Brumell JH, Muise AM, Sehgal R, Cohen Z, Koltun W, Shen B, Silverberg MS. The NOD2insC polymorphism is associated with worse outcome following ileal pouch-anal anastomosis for ulcerative colitis. Gut. 62: 1433-9. PMID 22879519 DOI: 10.1136/gutjnl-2011-301957  1
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Brumell JH, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/auto.19496  0.48
2012 Mrakovic A, Kay JG, Furuya W, Brumell JH, Botelho RJ. Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages. Traffic (Copenhagen, Denmark). 13: 1667-79. PMID 22909026 DOI: 10.1111/tra.12003  1
2012 Mijaljica D, Nazarko TY, Brumell JH, Huang WP, Komatsu M, Prescott M, Simonsen A, Yamamoto A, Zhang H, Klionsky DJ, Devenish RJ. Receptor protein complexes are in control of autophagy. Autophagy. 8: 1701-5. PMID 22874568 DOI: 10.4161/auto.21332  1
2012 Cemma M, Brumell JH. Interactions of pathogenic bacteria with autophagy systems. Current Biology : Cb. 22: R540-5. PMID 22790007 DOI: 10.1016/j.cub.2012.06.001  1
2012 Sarantis H, Balkin DM, De Camilli P, Isberg RR, Brumell JH, Grinstein S. Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)Pâ‚‚ and membrane scission. Cell Host & Microbe. 11: 117-28. PMID 22341461 DOI: 10.1016/j.chom.2012.01.010  1
2012 Huang J, Brumell JH. Microbiology: A sweet way of sensing danger. Nature. 482: 316-7. PMID 22337047 DOI: 10.1038/482316a  1
2012 Roppenser B, Grinstein S, Brumell JH. Modulation of host phosphoinositide metabolism during Salmonella invasion by the type III secreted effector SopB. Methods in Cell Biology. 108: 173-86. PMID 22325603 DOI: 10.1016/B978-0-12-386487-1.00009-2  1
2012 Brumell JH. Brucella "hitches a ride" with autophagy Cell Host and Microbe. 11: 2-4. PMID 22264507 DOI: 10.1016/j.chom.2012.01.003  1
2012 Lam GY, Czuczman MA, Higgins DE, Brumell JH. Interactions of Listeria monocytogenes with the autophagy system of host cells. Advances in Immunology. 113: 7-18. PMID 22244576 DOI: 10.1016/B978-0-12-394590-7.00008-7  1
2012 Muise AM, Xu W, Guo CH, Walters TD, Wolters VM, Fattouh R, Lam GY, Hu P, Murchie R, Sherlock M, Gana JC, Russell RK, Glogauer M, Duerr RH, ... ... Brumell JH, et al. NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2. Gut. 61: 1028-35. PMID 21900546 DOI: 10.1136/gutjnl-2011-300078  1
2012 Muise AM, Fattouh R, Lam GY, Dhillon S, Brumell JH. The authors' reply Gut. 61: 1097-1098. DOI: 10.1136/gutjnl-2011-301469  1
2011 Lam GY, Fattouh R, Muise AM, Grinstein S, Higgins DE, Brumell JH. Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host & Microbe. 10: 627-34. PMID 22177565 DOI: 10.1016/j.chom.2011.11.005  1
2011 Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, et al. A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy. 7: 1273-94. PMID 21997368 DOI: 10.4161/auto.7.11.17661  1
2011 Kaniuk NA, Canadien V, Bagshaw RD, Bakowski M, Braun V, Landekic M, Mitra S, Huang J, Heo WD, Meyer T, Pelletier L, Andrews-Polymenis H, McClelland M, Pawson T, Grinstein S, ... Brumell JH, et al. Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer. Cellular Microbiology. 13: 1812-23. PMID 21824248 DOI: 10.1111/j.1462-5822.2011.01663.x  1
2011 Muise AM, Walters T, Xu W, Shen-Tu G, Guo CH, Fattouh R, Lam GY, Wolters VM, Bennitz J, van Limbergen J, Renbaum P, Kasirer Y, Ngan BY, Turner D, Denson LA, ... ... Brumell JH, et al. Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis. Gastroenterology. 141: 633-41. PMID 21684284 DOI: 10.1053/j.gastro.2011.04.057  1
2011 Shahnazari S, Namolovan A, Mogridge J, Kim PK, Brumell JH. Bacterial toxins can inhibit host cell autophagy through cAMP generation Autophagy. 7: 957-965. PMID 21606683 DOI: 10.4161/auto.7.9.16435  1
2011 Qiu W, Zhang J, Dekker MJ, Wang H, Huang J, Brumell JH, Adeli K. Hepatic autophagy mediates endoplasmic reticulum stress-induced degradation of misfolded apolipoprotein B. Hepatology (Baltimore, Md.). 53: 1515-25. PMID 21360721 DOI: 10.1002/hep.24269  1
2011 Shahnazari S, Brumell JH. Mechanisms and consequences of bacterial targeting by the autophagy pathway. Current Opinion in Microbiology. 14: 68-75. PMID 21112809 DOI: 10.1016/j.mib.2010.11.001  1
2011 Shahnazari S, Namolovan A, Klionsky DJ, Brumell JH. A role for diacylglycerol in antibacterial autophagy. Autophagy. 7: 331-3. PMID 21079417 DOI: 10.4161/auto.7.3.14045  1
2011 Cemma M, Kim PK, Brumell JH. The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway Autophagy. 7: 341-345. PMID 21079414 DOI: 10.4161/auto.7.3.14046  1
2011 Huang J, Birmingham CL, Shahnazari S, Shiu J, Zheng YT, Smith AC, Campellone KG, Heo WD, Gruenheid S, Meyer T, Welch MD, Ktistakis NT, Kim PK, Klionsky DJ, Brumell JH. Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase. Autophagy. 7: 17-26. PMID 20980813 DOI: 10.4161/auto.7.1.13840  1
2011 Kaniuk NA, Lam GY, Ma C, Galindo-Mata E, Jones N, Vallance BA, Brumell JH. Citrobacter rodentium infection induces MyD88-dependent formation of ubiquitinated protein aggregates in the intestinal epithelium. Journal of Innate Immunity. 3: 83-98. PMID 20962508 DOI: 10.1159/000320644  1
2011 Huang J, Lam GY, Brumell JH. Autophagy signaling through reactive oxygen species. Antioxidants & Redox Signaling. 14: 2215-31. PMID 20874258 DOI: 10.1089/ars.2010.3554  1
2010 Lam GY, Huang J, Brumell JH. The many roles of NOX2 NADPH oxidase-derived ROS in immunity. Seminars in Immunopathology. 32: 415-30. PMID 20803017 DOI: 10.1007/s00281-010-0221-0  1
2010 Braun V, Brumell JH. Bacterial invasion: entry through the exocyst door. Current Biology : Cb. 20: R677-9. PMID 20728054 DOI: 10.1016/j.cub.2010.06.047  1
2010 Kaniuk NA, Brumell JH. Examining ubiquitinated protein aggregates in tissue sections. Methods in Molecular Biology (Clifton, N.J.). 648: 175-82. PMID 20700712 DOI: 10.1007/978-1-60761-756-3_11  1
2010 Shahnazari S, Yen WL, Birmingham CL, Shiu J, Namolovan A, Zheng YT, Nakayama K, Klionsky DJ, Brumell JH. A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy. Cell Host & Microbe. 8: 137-46. PMID 20674539 DOI: 10.1016/j.chom.2010.07.002  1
2010 Bakowski MA, Braun V, Lam GY, Yeung T, Heo WD, Meyer T, Finlay BB, Grinstein S, Brumell JH. The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host & Microbe. 7: 453-62. PMID 20542249 DOI: 10.1016/j.chom.2010.05.011  1
2010 Braun V, Wong A, Landekic M, Hong WJ, Grinstein S, Brumell JH. Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cellular Microbiology. 12: 1352-67. PMID 20482551 DOI: 10.1111/j.1462-5822.2010.01476.x  1
2010 Lynch-Day MA, Bhandari D, Menon S, Huang J, Cai H, Bartholomew CR, Brumell JH, Ferro-Novick S, Klionsky DJ. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proceedings of the National Academy of Sciences of the United States of America. 107: 7811-6. PMID 20375281 DOI: 10.1073/pnas.1000063107  1
2010 Cooper CA, Zhang K, Andres SN, Fang Y, Kaniuk NA, Hannemann M, Brumell JH, Foster LJ, Junop MS, Coombes BK. Structural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a host. Plos Pathogens. 6: e1000751. PMID 20140193 DOI: 10.1371/journal.ppat.1000751  1
2009 Shahnazari S, Brumell JH. Eating twice for the sake of immunity: a phagocytic receptor that activates autophagy. Cell Host & Microbe. 6: 297-8. PMID 19837368 DOI: 10.1016/j.chom.2009.10.003  1
2009 Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. Journal of Immunology (Baltimore, Md. : 1950). 183: 5909-16. PMID 19812211 DOI: 10.4049/jimmunol.0900441  1
2009 Huang J, Brumell JH. Autophagy in immunity against intracellular bacteria. Current Topics in Microbiology and Immunology. 335: 189-215. PMID 19802566 DOI: 10.1007/978-3-642-00302-8_9  1
2009 Huang J, Brumell JH. NADPH oxidases contribute to autophagy regulation. Autophagy. 5: 887-9. PMID 19550142  1
2009 Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, Glogauer M, Grinstein S, Brumell JH. Activation of antibacterial autophagy by NADPH oxidases. Proceedings of the National Academy of Sciences of the United States of America. 106: 6226-31. PMID 19339495 DOI: 10.1073/pnas.0811045106  1
2009 Birmingham CL, Brumell JH. Methods to monitor autophagy of Salmonella enterica serovar Typhimurium. Methods in Enzymology. 452: 325-43. PMID 19200891 DOI: 10.1016/S0076-6879(08)03620-3  1
2009 Szeto J, Namolovan A, Osborne SE, Coombes BK, Brumell JH. Salmonella-containing vacuoles display centrifugal movement associated with cell-to-cell transfer in epithelial cells. Infection and Immunity. 77: 996-1007. PMID 19103768 DOI: 10.1128/IAI.01275-08  1
2009 Hartley T, Brumell J, Volchuk A. Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells. American Journal of Physiology. Endocrinology and Metabolism. 296: E1-10. PMID 18812463 DOI: 10.1152/ajpendo.90538.2008  1
2008 Lam GY, Brumell JH. Cell biology: A Listeria escape trick. Nature. 455: 1186-7. PMID 18972010 DOI: 10.1038/4551186a  1
2008 Bakowski MA, Braun V, Brumell JH. Salmonella-containing vacuoles: directing traffic and nesting to grow. Traffic (Copenhagen, Denmark). 9: 2022-31. PMID 18778407 DOI: 10.1111/j.1600-0854.2008.00827.x  1
2008 Mallo GV, Espina M, Smith AC, Terebiznik MR, Alemán A, Finlay BB, Rameh LE, Grinstein S, Brumell JH. SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. The Journal of Cell Biology. 182: 741-52. PMID 18725540 DOI: 10.1083/jcb.200804131  1
2008 Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH. Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication. Infection and Immunity. 76: 2722-35. PMID 18411289 DOI: 10.1128/IAI.00152-08  1
2008 Birmingham CL, Higgins DE, Brumell JH. Avoiding death by autophagy: interactions of Listeria monocytogenes with the macrophage autophagy system. Autophagy. 4: 368-71. PMID 18216493  1
2008 Birmingham CL, Canadien V, Kaniuk NA, Steinberg BE, Higgins DE, Brumell JH. Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles. Nature. 451: 350-4. PMID 18202661 DOI: 10.1038/nature06479  1
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Brumell JH, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/auto.5338  1
2008 Király MA, Bates HE, Kaniuk NA, Yue JT, Brumell JH, Matthews SG, Riddell MC, Vranic M. Swim training prevents hyperglycemia in ZDF rats: mechanisms involved in the partial maintenance of beta-cell function. American Journal of Physiology. Endocrinology and Metabolism. 294: E271-83. PMID 18029442 DOI: 10.1152/ajpendo.00476.2007  1
2007 Brumell JH, Scidmore MA. Manipulation of rab GTPase function by intracellular bacterial pathogens. Microbiology and Molecular Biology Reviews : Mmbr. 71: 636-52. PMID 18063721 DOI: 10.1128/MMBR.00023-07  1
2007 Boyle EC, Brown NF, Brumell JH, Finlay BB. Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells. Microbiology (Reading, England). 153: 3517-26. PMID 17906149 DOI: 10.1099/mic.0.2007/008581-0  1
2007 Bakowski MA, Cirulis JT, Brown NF, Finlay BB, Brumell JH. SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion. Cellular Microbiology. 9: 2839-55. PMID 17696999 DOI: 10.1111/j.1462-5822.2007.01000.x  1
2007 Birmingham CL, Canadien V, Gouin E, Troy EB, Yoshimori T, Cossart P, Higgins DE, Brumell JH. Listeria monocytogenes evades killing by autophagy during colonization of host cells. Autophagy. 3: 442-51. PMID 17568179  1
2007 Binker MG, Cosen-Binker LI, Terebiznik MR, Mallo GV, McCaw SE, Eskelinen EL, Willenborg M, Brumell JH, Saftig P, Grinstein S, Gray-Owen SD. Arrested maturation of Neisseria-containing phagosomes in the absence of the lysosome-associated membrane proteins, LAMP-1 and LAMP-2. Cellular Microbiology. 9: 2153-66. PMID 17506821 DOI: 10.1111/j.1462-5822.2007.00946.x  1
2007 Kaniuk NA, Kiraly M, Bates H, Vranic M, Volchuk A, Brumell JH. Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy. Diabetes. 56: 930-9. PMID 17395740 DOI: 10.2337/db06-1160  1
2007 Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S. Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. The Journal of General Physiology. 129: 267-83. PMID 17389247 DOI: 10.1085/jgp.200609656  1
2007 Smith AC, Won DH, Braun V, Jiang X, Macrae C, Casanova JE, Scidmore MA, Grinstein S, Meyer T, Brumell JH. A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium Journal of Cell Biology. 176: 263-268. PMID 17261845 DOI: 10.1083/jcb.200611056  1
2006 Szeto J, Kaniuk NA, Canadien V, Nisman R, Mizushima N, Yoshimori T, Bazett-Jones DP, Brumell JH. ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy. Autophagy. 2: 189-99. PMID 16874109  1
2006 Birmingham CL, Brumell JH. Autophagy recognizes intracellular Salmonella enterica serovar Typhimurium in damaged vacuoles. Autophagy. 2: 156-8. PMID 16874057  1
2006 Brown NF, Szeto J, Jiang X, Coombes BK, Finlay BB, Brumell JH. Mutational analysis of Salmonella translocated effector members SifA and SopD2 reveals domains implicated in translocation, subcellular localization and function. Microbiology (Reading, England). 152: 2323-43. PMID 16849798 DOI: 10.1099/mic.0.28995-0  1
2006 Birmingham CL, Smith AC, Bakowski MA, Yoshimori T, Brumell JH. Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. The Journal of Biological Chemistry. 281: 11374-83. PMID 16495224 DOI: 10.1074/jbc.M509157200  1
2005 Szeto J, Brumell JH. Intracellular Voyeurism: Examining the Modulation of Host Cell Activities bySalmonella enterica Serovar Typhimurium. Ecosal Plus. 1. PMID 26443522 DOI: 10.1128/ecosalplus.2.2.2  1
2005 Ohlson MB, Fluhr K, Birmingham CL, Brumell JH, Miller SI. SseJ deacylase activity by Salmonella enterica serovar Typhimurium promotes virulence in mice. Infection and Immunity. 73: 6249-59. PMID 16177296 DOI: 10.1128/IAI.73.10.6249-6259.2005  1
2005 Smith AC, Cirulis JT, Casanova JE, Scidmore MA, Brumell JH. Interaction of the Salmonella-containing vacuole with the endocytic recycling system. The Journal of Biological Chemistry. 280: 24634-41. PMID 15886200 DOI: 10.1074/jbc.M500358200  1
2005 Canadien V, Tan T, Zilber R, Szeto J, Perrin AJ, Brumell JH. Cutting edge: microbial products elicit formation of dendritic cell aggresome-like induced structures in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 174: 2471-5. PMID 15728449  1
2005 Birmingham CL, Jiang X, Ohlson MB, Miller SI, Brumell JH. Salmonella-induced filament formation is a dynamic phenotype induced by rapidly replicating Salmonella enterica serovar typhimurium in epithelial cells. Infection and Immunity. 73: 1204-8. PMID 15664965 DOI: 10.1128/IAI.73.2.1204-1208.2005  1
2004 Jiang X, Rossanese OW, Brown NF, Kujat-Choy S, Galán JE, Finlay BB, Brumell JH. The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Molecular Microbiology. 54: 1186-98. PMID 15554961 DOI: 10.1111/j.1365-2958.2004.04344.x  1
2004 Coombes BK, Brown NF, Valdez Y, Brumell JH, Finlay BB. Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL. The Journal of Biological Chemistry. 279: 49804-15. PMID 15383528 DOI: 10.1074/jbc.M404299200  1
2004 Harrison RE, Brumell JH, Khandani A, Bucci C, Scott CC, Jiang X, Finlay BB, Grinstein S. Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Molecular Biology of the Cell. 15: 3146-54. PMID 15121880 DOI: 10.1091/mbc.E04-02-0092  1
2004 Perrin AJ, Jiang X, Birmingham CL, So NS, Brumell JH. Recognition of bacteria in the cytosol of Mammalian cells by the ubiquitin system. Current Biology : Cb. 14: 806-11. PMID 15120074 DOI: 10.1016/j.cub.2004.04.033  1
2004 Brumell JH, Grinstein S. Salmonella redirects phagosomal maturation. Current Opinion in Microbiology. 7: 78-84. PMID 15036145 DOI: 10.1016/j.mib.2003.12.005  1
2003 Brumell JH, Grinstein S. Role of lipid-mediated signal transduction in bacterial internalization. Cellular Microbiology. 5: 287-97. PMID 12713488 DOI: 10.1046/j.1462-5822.2003.00273.x  1
2003 Brumell JH, Kujat-Choy S, Brown NF, Vallance BA, Knodler LA, Finlay BB. SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells. Traffic (Copenhagen, Denmark). 4: 36-48. PMID 12535274 DOI: 10.1034/j.1600-0854.2003.40106.x  1
2002 Brumell JH, Tang P, Zaharik ML, Finlay BB. Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infection and Immunity. 70: 3264-70. PMID 12011022 DOI: 10.1128/IAI.70.6.3264-3270.2002  1
2002 Brumell JH, Goosney DL, Finlay BB. SifA, a type III secreted effector of Salmonella typhimurium, directs Salmonella-induced filament (Sif) formation along microtubules. Traffic (Copenhagen, Denmark). 3: 407-15. PMID 12010459 DOI: 10.1034/j.1600-0854.2002.30604.x  1
2002 Steele-Mortimer O, Brumell JH, Knodler LA, Méresse S, Lopez A, Finlay BB. The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells. Cellular Microbiology. 4: 43-54. PMID 11856172 DOI: 10.1046/j.1462-5822.2002.00170.x  1
2002 Brumell JH, Perrin AJ, Goosney DL, Finlay BB. Microbial pathogenesis: New niches for Salmonella Current Biology. 12: R15-R17. PMID 11790317 DOI: 10.1016/S0960-9822(01)00640-6  1
2001 Brumell JH, Tang P, Mills SD, Finlay BB. Characterization of Salmonella-induced filaments (Sifs) reveals a delayed interaction between Salmonella-containing vacuoles and late endocytic compartments Traffic. 2: 643-653. PMID 11555418 DOI: 10.1034/j.1600-0854.2001.20907.x  1
2001 Brumell JH, Rosenberger CM, Gotto GT, Marcus SL, Finlay BB. SifA permits survival and replication of Salmonella typhimurium in murine macrophages. Cellular Microbiology. 3: 75-84. PMID 11207622 DOI: 10.1046/j.1462-5822.2001.00087.x  1
2001 Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS. Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. The Journal of Biological Chemistry. 276: 4772-80. PMID 11092884 DOI: 10.1074/jbc.M007792200  1
2000 Rosenberger CM, Brumell JH, Finlay BB. Microbial pathogenesis: lipid rafts as pathogen portals. Current Biology : Cb. 10: R823-5. PMID 11102822 DOI: 10.1016/S0960-9822(00)00788-0  1
2000 Finlay BB, Brumell JH. Salmonella interactions with host cells: In vitro to in vivo Philosophical Transactions of the Royal Society B: Biological Sciences. 355: 623-631. PMID 10874735  1
2000 Brumell JH, Marcus SL, Finlay BB. N-terminal conservation of putative type III secreted effectors of Salmonella typhimurium. Molecular Microbiology. 36: 773-4. PMID 10844665 DOI: 10.1046/j.1365-2958.2000.01878.x  1
2000 Marcus SL, Brumell JH, Pfeifer CG, Finlay BB. Salmonella pathogenicity islands: big virulence in small packages. Microbes and Infection / Institut Pasteur. 2: 145-56. PMID 10742687 DOI: 10.1016/S1286-4579(00)00273-2  1
1999 Brumell JH, Howard JC, Craig K, Grinstein S, Schreiber AD, Tyers M. Expression of the protein kinase C substrate pleckstrin in macrophages: association with phagosomal membranes. Journal of Immunology (Baltimore, Md. : 1950). 163: 3388-95. PMID 10477609  1
1999 Brumell JH, Steele-Mortimer O, Finlay BB. Bacterial invasion: Force feeding by Salmonella Current Biology. 9. PMID 10226015 DOI: 10.1016/S0960-9822(99)80178-X  1
1997 Brumell JH, Craig KL, Ferguson D, Tyers M, Grinstein S. Phosphorylation and subcellular redistribution of pleckstrin in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 158: 4862-71. PMID 9144502  1
1997 Brumell JH, Chan CK, Butler J, Borregaard N, Siminovitch KA, Grinstein S, Downey GP. Regulation of Src homology 2-containing tyrosine phosphatase 1 during activation of human neutrophils: Role of protein kinase C Journal of Biological Chemistry. 272: 875-882. PMID 8995376 DOI: 10.1074/jbc.272.2.875  1
1996 Nanda A, Brumell JH, Nordström T, Kjeldsen L, Sengeløv H, Borregaard N, Rotstem OD, Grinstein S. Activation of proton pumping in human neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases Journal of Biological Chemistry. 271: 15963-15970. PMID 8663143 DOI: 10.1074/jbc.271.27.15963  1
1996 Brumell JH, Burkhardt AL, Bolen JB, Grinstein S. Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils Journal of Biological Chemistry. 271: 1455-1461. PMID 8576138 DOI: 10.1074/jbc.271.3.1455  1
1996 Brumell JH, Ferguson D, Craig K, Tyers M, Grinstein S. Regulation of pleckstrin phosphorylation in human neutrophils Faseb Journal. 10.  1
1995 Brumell JH, Volchuk A, Sengelov H, Borregaard N, Cieutat AM, Bainton DF, Grinstein S, Klip A. Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments Journal of Immunology. 155: 5750-5759. PMID 7499863  1
1994 Brumell JH, Grinstein S. Serine/threonine kinase activation in human neutrophils: Relationship to tyrosine phosphorylation Am.J.Physiol.. 267.  1
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