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Lakshmi Krishnan - Publications

Affiliations: 
Biochimie, microbiologie et immunologie / Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
Immunology, Oncology, Cell Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Agbayani G, Clark K, Sandhu JK, Hewitt M, Sad S, Murphy SP, Krishnan L. IFN-alpha receptor deficiency enhances host resistance to oral Salmonella enterica serovar Typhimurium infection during murine pregnancy. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13454. PMID 33991140 DOI: 10.1111/aji.13454  0.311
2019 Perry ID, Nguyen T, Sherina V, Love TMT, Miller RK, Krishnan L, Murphy SP. Analysis of the capacity of Salmonella enterica Typhimurium to infect the human Placenta. Placenta. 83: 43-52. PMID 31477206 DOI: 10.1016/J.Placenta.2019.06.386  0.369
2019 Perry ID, Krishnan L, Murphy SP. SLC11A1 is expressed in the human placenta across multiple gestational ages. Placenta. 75: 23-26. PMID 30712662 DOI: 10.1016/J.Placenta.2018.11.009  0.372
2018 Akache B, Stark FC, Jia Y, Deschatelets L, Dudani R, Harrison BA, Agbayani G, Williams D, Jamshidi MP, Krishnan L, McCluskie MJ. Sulfated archaeol glycolipids: Comparison with other immunological adjuvants in mice. Plos One. 13: e0208067. PMID 30513093 DOI: 10.1371/Journal.Pone.0208067  0.358
2018 Agbayani G, Wachholz K, Murphy SP, Sad S, Krishnan L. Type I interferons differentially modulate maternal host immunity to infection by Listeria monocytogenes and Salmonella enterica serovar Typhimurium during pregnancy. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13068. PMID 30376200 DOI: 10.1111/Aji.13068  0.404
2018 Agbayani G, Gurnani K, Zafer A, Sad S, Krishnan L. Lack of functional selectin-ligand interactions enhances innate immune resistance to systemic Listeria monocytogenes infection. Journal of Leukocyte Biology. 103: 355-368. PMID 29345354 DOI: 10.1002/Jlb.4A1216-499R  0.408
2017 Agbayani G, Wachholz K, Chattopadhyay A, Gurnani K, Murphy SP, Krishnan L. Modulation of Th17 and regulatory T-cell responses during murine pregnancy contributes to increased maternal susceptibility to Salmonella Typhimurium infection. American Journal of Reproductive Immunology (New York, N.Y. : 1989). PMID 28990696 DOI: 10.1111/Aji.12742  0.341
2017 Patel R, Kim K, Shutinoski B, Wachholz K, Krishnan L, Sad S. Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells. Cell Death and Differentiation. PMID 28686578 DOI: 10.1038/Cdd.2017.112  0.405
2016 Joseph J, Ametepe ES, Haribabu N, Agbayani G, Krishnan L, Blais A, Sad S. Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium. Nature Communications. 7: 12748. PMID 27599659 DOI: 10.1038/Ncomms12748  0.405
2014 Wachholz K, Agbayani G, Nguyen T, Gurnani K, Krishnan L. Placental infection by Salmonella enterica typhimurium in a murine model: mechanisms of pathogenesis and role of inflammatory cell death Placenta. 35. DOI: 10.1016/J.Placenta.2014.06.207  0.435
2014 Nguyen T, Perry I, Murphy S, Gruslin A, Krishnan L. Salmonella enterica serovar typhimurium productively infects human primary trophoblast cells and induces inflammatory cell death Placenta. 35: A62-A63. DOI: 10.1016/J.Placenta.2014.06.203  0.37
2013 Nguyen T, Robinson N, Allison SE, Coombes BK, Sad S, Krishnan L. IL-10 produced by trophoblast cells inhibits phagosome maturation leading to profound intracellular proliferation of Salmonella enterica Typhimurium. Placenta. 34: 765-74. PMID 23834952 DOI: 10.1016/J.Placenta.2013.06.003  0.402
2013 Krishnan L, Nguyen T, McComb S. From mice to women: the conundrum of immunity to infection during pregnancy. Journal of Reproductive Immunology. 97: 62-73. PMID 23432873 DOI: 10.1016/J.Jri.2012.10.015  0.407
2012 Tzelepis F, Alcon V, Dudani R, Gurnani K, Zafer A, Everson ES, Young KG, Rüssmann H, Krishnan L, Sad S. Modulation of antigenic location converts chronic into acute infection by forcing CD8+ T cell recognition. Cell Reports. 2: 1710-21. PMID 23219554 DOI: 10.1016/J.Celrep.2012.10.024  0.417
2012 Robinson N, McComb S, Mulligan R, Dudani R, Krishnan L, Sad S. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nature Immunology. 13: 954-62. PMID 22922364 DOI: 10.1038/Ni.2397  0.375
2012 McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death and Differentiation. 19: 1791-801. PMID 22576661 DOI: 10.1038/Cdd.2012.59  0.308
2011 Young KG, Maclean S, Dudani R, Krishnan L, Sad S. CD8+ T cells primed in the periphery provide time-bound immune-surveillance to the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 187: 1192-200. PMID 21715683 DOI: 10.4049/Jimmunol.1100695  0.382
2010 Chattopadhyay A, Robinson N, Sandhu JK, Finlay BB, Sad S, Krishnan L. Salmonella enterica serovar Typhimurium-induced placental inflammation and not bacterial burden correlates with pathology and fatal maternal disease. Infection and Immunity. 78: 2292-301. PMID 20194592 DOI: 10.1128/Iai.01186-09  0.403
2010 Krishnan L, Pejcic-Karapetrovic B, Gurnani K, Zafer A, Sad S. Pregnancy does not deter the development of a potent maternal protective CD8+ T-cell acquired immune response against Listeria monocytogenes despite preferential placental colonization. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 63: 54-65. PMID 19912156 DOI: 10.1111/J.1600-0897.2009.00766.X  0.401
2010 Nguyen T, Chattopadhyay A, Krishnan L. Host immune and pathogen virulence factors that contribute to placental colonization by Salmonella typhimurium Journal of Reproductive Immunology. 86: 49-50. DOI: 10.1016/J.Jri.2010.06.101  0.319
2009 Russell MS, Dudani R, Krishnan L, Sad S. IFN-gamma expressed by T cells regulates the persistence of antigen presentation by limiting the survival of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 7710-8. PMID 19923462 DOI: 10.4049/Jimmunol.0901274  0.315
2009 Albaghdadi H, Robinson N, Finlay B, Krishnan L, Sad S. Selectively reduced intracellular proliferation of Salmonella enterica serovar typhimurium within APCs limits antigen presentation and development of a rapid CD8 T cell response. Journal of Immunology (Baltimore, Md. : 1950). 183: 3778-87. PMID 19692639 DOI: 10.4049/Jimmunol.0900843  0.381
2008 Dudani R, Murali-Krishna K, Krishnan L, Sad S. IFN-gamma induces the erosion of preexisting CD8 T cell memory during infection with a heterologous intracellular bacterium. Journal of Immunology (Baltimore, Md. : 1950). 181: 1700-9. PMID 18641306 DOI: 10.4049/Jimmunol.181.3.1700  0.39
2008 Sad S, Dudani R, Gurnani K, Russell M, van Faassen H, Finlay B, Krishnan L. Pathogen proliferation governs the magnitude but compromises the function of CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 5853-61. PMID 18424704 DOI: 10.4049/Jimmunol.180.9.5853  0.418
2007 Pejcic-Karapetrovic B, Gurnani K, Russell MS, Finlay BB, Sad S, Krishnan L. Pregnancy impairs the innate immune resistance to Salmonella typhimurium leading to rapid fatal infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 6088-96. PMID 17947683 DOI: 10.4049/Jimmunol.179.9.6088  0.413
2007 Russell MS, Iskandar M, Mykytczuk OL, Nash JH, Krishnan L, Sad S. A reduced antigen load in vivo, rather than weak inflammation, causes a substantial delay in CD8+ T cell priming against Mycobacterium bovis (bacillus Calmette-Guérin). Journal of Immunology (Baltimore, Md. : 1950). 179: 211-20. PMID 17579040 DOI: 10.4049/Jimmunol.179.1.211  0.422
2007 Krishnan L, Gurnani K, Dicaire CJ, van Faassen H, Zafer A, Kirschning CJ, Sad S, Sprott GD. Rapid clonal expansion and prolonged maintenance of memory CD8+ T cells of the effector (CD44highCD62Llow) and central (CD44highCD62Lhigh) phenotype by an archaeosome adjuvant independent of TLR2. Journal of Immunology (Baltimore, Md. : 1950). 178: 2396-406. PMID 17277146 DOI: 10.4049/Jimmunol.178.4.2396  0.389
2006 Luu RA, Gurnani K, Dudani R, Kammara R, van Faassen H, Sirard JC, Krishnan L, Sad S. Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium. Journal of Immunology (Baltimore, Md. : 1950). 177: 1516-25. PMID 16849458 DOI: 10.4049/Jimmunol.177.3.1516  0.359
2005 van Faassen H, Saldanha M, Gilbertson D, Dudani R, Krishnan L, Sad S. Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset. Journal of Immunology (Baltimore, Md. : 1950). 174: 5341-50. PMID 15843531 DOI: 10.4049/Jimmunol.174.9.5341  0.31
2004 van Faassen H, Dudani R, Krishnan L, Sad S. Prolonged antigen presentation, APC-, and CD8+ T cell turnover during mycobacterial infection: comparison with Listeria monocytogenes. Journal of Immunology (Baltimore, Md. : 1950). 172: 3491-500. PMID 15004149 DOI: 10.4049/Jimmunol.172.6.3491  0.341
2002 Dudani R, Chapdelaine Y, Faassen Hv Hv, Smith DK, Shen H, Krishnan L, Sad S. Multiple mechanisms compensate to enhance tumor-protective CD8(+) T cell response in the long-term despite poor CD8(+) T cell priming initially: comparison between an acute versus a chronic intracellular bacterium expressing a model antigen. Journal of Immunology (Baltimore, Md. : 1950). 168: 5737-45. PMID 12023374 DOI: 10.4049/Jimmunol.168.11.5737  0.315
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