| Year |
Citation |
Score |
| 2024 |
Vahkal B, Altosaar I, Ariana A, Jabbour J, Pantieras F, Daniel R, Tremblay É, Sad S, Beaulieu JF, Côté M, Ferretti E. Human milk extracellular vesicles modulate inflammation and cell survival in intestinal and immune cells. Pediatric Research. PMID 39609615 DOI: 10.1038/s41390-024-03757-5 |
0.316 |
|
| 2024 |
Yadav S, El Hamra R, Alturki NA, Ariana A, Bhan A, Hurley K, Gaestel M, Blackshear PJ, Blais A, Sad S. Regulation of Zfp36 by ISGF3 and MK2 restricts the expression of inflammatory cytokines during necroptosis stimulation. Cell Death & Disease. 15: 574. PMID 39117638 DOI: 10.1038/s41419-024-06964-4 |
0.405 |
|
| 2023 |
Khan AUH, Ali AK, Marr B, Jo D, Ahmadvand S, Fong-McMaster C, Almutairi SM, Wang L, Sad S, Harper ME, Lee SH. The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis. Cellular & Molecular Immunology. PMID 37553427 DOI: 10.1038/s41423-023-01071-4 |
0.386 |
|
| 2023 |
Thakker P, Ariana A, Hajjar S, Cai D, Rijal D, Sad S. XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively. Plos Pathogens. 19: e1011455. PMID 37347786 DOI: 10.1371/journal.ppat.1011455 |
0.404 |
|
| 2022 |
Jahan S, Awaja N, Hess B, Hajjar S, Sad S, Lohnes D. The transcription factor Cdx2 regulates inflammasome activity through expression of the NLRP3 suppressor TRIM31 to maintain intestinal homeostasis. The Journal of Biological Chemistry. 102386. PMID 35985421 DOI: 10.1016/j.jbc.2022.102386 |
0.304 |
|
| 2021 |
Cai D, Brickey WJ, Ting JP, Sad S. Isolates of Salmonella typhimurium circumvent NLRP3 inflammasome recognition in macrophages during the chronic phase of infection. The Journal of Biological Chemistry. 298: 101461. PMID 34864057 DOI: 10.1016/j.jbc.2021.101461 |
0.415 |
|
| 2021 |
Hajjar S, Nathan N, Joseph J, Mottawea W, Ariana A, Pyatibrat S, Harper ME, Alain T, Blais A, Russell RC, Sad S. Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10 model of colitis. Cell Death and Differentiation. PMID 34588632 DOI: 10.1038/s41418-021-00876-y |
0.378 |
|
| 2021 |
Phuong MS, Hernandez RE, Wolter DJ, Hoffman LR, Sad S. Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response. Cell Death & Disease. 12: 241. PMID 33664232 DOI: 10.1038/s41419-021-03526-w |
0.359 |
|
| 2020 |
Rana A, de Almeida FC, Paico Montero HA, Gonzales Carazas MM, Bortoluci KR, Sad S, Amarante-Mendes GP. RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified . Frontiers in Immunology. 11: 536. PMID 32328060 DOI: 10.3389/Fimmu.2020.00536 |
0.471 |
|
| 2020 |
Sadh S, Hajjar S, Ariana A, Phuong MS, Cai D, Thakker P, Sad S. Coating M-CSF on plastic surface results in the generation of increased numbers of macrophages in vitro. Journal of Immunological Methods. 112788. PMID 32304707 DOI: 10.1016/J.Jim.2020.112788 |
0.39 |
|
| 2020 |
Ariana A, Alturki NA, Hajjar S, Stumpo DJ, Tiedje C, Alnemri ES, Gaestel M, Blackshear PJ, Sad S. Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages. The Journal of Biological Chemistry. PMID 32094226 DOI: 10.1074/Jbc.Ra119.011633 |
0.499 |
|
| 2019 |
Shutinoski B, Hakimi M, Harmsen IE, Lunn M, Rocha J, Lengacher N, Zhou YY, Khan J, Nguyen A, Hake-Volling Q, El-Kodsi D, Li J, Alikashani A, Beauchamp C, Majithia J, ... ... Sad S, et al. alleles modulate inflammation during microbial infection of mice in a sex-dependent manner. Science Translational Medicine. 11. PMID 31554740 DOI: 10.1126/Scitranslmed.Aas9292 |
0.763 |
|
| 2019 |
Shutinoski B, Patel R, Tomlinson JJ, Schlossmacher MG, Sad S. Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome. Microbes and Infection. PMID 31430539 DOI: 10.1016/J.Micinf.2019.08.002 |
0.802 |
|
| 2019 |
Losier TT, Akuma M, McKee-Muir OC, LeBlond ND, Suk Y, Alsaadi RM, Guo Z, Reshke R, Sad S, Campbell-Valois FX, Gibbings DJ, Fullerton MD, Russell RC. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Reports. 26: 2150-2165.e5. PMID 30784596 DOI: 10.1016/J.Celrep.2019.01.062 |
0.421 |
|
| 2019 |
Phuong MS, Hernandez RE, Sad S. 413. Differences in Inflammatory Mechanisms in Pseudomonas aeruginosa and Staphyloccoccus auereus Infections in Cystic Fibrosis Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz360.486 |
0.363 |
|
| 2018 |
Agbayani G, Wachholz K, Murphy SP, Sad S, Krishnan L. Type I interferons differentially modulate maternal host immunity to infection by Listeria monocytogenes and Salmonella enterica serovar Typhimurium during pregnancy. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13068. PMID 30376200 DOI: 10.1111/Aji.13068 |
0.413 |
|
| 2018 |
Wight A, Mahmoud AB, Scur M, Tu MM, Rahim MMA, Sad S, Makrigiannis AP. Critical role for the Ly49 family of class I MHC receptors in adaptive natural killer cell responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 30249666 DOI: 10.1073/Pnas.1722374115 |
0.374 |
|
| 2018 |
Rijal D, Ariana A, Wight A, Kim K, Alturki NA, Aamir Z, Ametepe E, Korneluk RG, Tiedje C, Menon MB, Gaestel M, McComb S, Sad S. Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1. The Journal of Biological Chemistry. PMID 29899110 DOI: 10.1074/Jbc.Ra118.003614 |
0.712 |
|
| 2018 |
Alturki NA, McComb S, Ariana A, Rijal D, Korneluk RG, Sun SC, Alnemri E, Sad S. Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis. Cell Death & Disease. 9: 592. PMID 29789521 DOI: 10.1038/S41419-018-0672-0 |
0.679 |
|
| 2018 |
Agbayani G, Gurnani K, Zafer A, Sad S, Krishnan L. Lack of functional selectin-ligand interactions enhances innate immune resistance to systemic Listeria monocytogenes infection. Journal of Leukocyte Biology. 103: 355-368. PMID 29345354 DOI: 10.1002/Jlb.4A1216-499R |
0.471 |
|
| 2018 |
Karunakaran D, Geoffrion M, Wei L, Gan W, Perisic L, Maegdefessel L, Hedin U, Sad S, Guo L, Kolodgie F, Ruddy T, Virmani R, Rayner K. Therapeutically Targeting the Kinase Activity or Gene Expression of RIP1 Reduces Inflammation-driven Atherosclerosis and Promotes Plaque Stability Atherosclerosis Supplements. 32: 11-12. DOI: 10.1016/J.Atherosclerosissup.2018.04.035 |
0.325 |
|
| 2017 |
Patel R, Kim K, Shutinoski B, Wachholz K, Krishnan L, Sad S. Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells. Cell Death and Differentiation. PMID 28686578 DOI: 10.1038/Cdd.2017.112 |
0.785 |
|
| 2017 |
Tomlinson JJ, Shutinoski B, Dong L, Meng F, Elleithy D, Lengacher NA, Nguyen AP, Cron GO, Jiang Q, Roberson ED, Nussbaum RL, Majbour NK, El-Agnaf OM, Bennett SA, Lagace DC, ... ... Sad S, et al. Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 28477284 DOI: 10.1007/S00702-017-1726-7 |
0.733 |
|
| 2017 |
Deguise MO, De Repentigny Y, McFall E, Auclair N, Sad S, Kothary R. Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice. Human Molecular Genetics. PMID 28108555 DOI: 10.1093/Hmg/Ddw434 |
0.337 |
|
| 2016 |
Joseph J, Ametepe ES, Haribabu N, Agbayani G, Krishnan L, Blais A, Sad S. Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium. Nature Communications. 7: 12748. PMID 27599659 DOI: 10.1038/Ncomms12748 |
0.514 |
|
| 2016 |
Karunakaran D, Geoffrion M, Wei L, Gan W, Richards L, Shangari P, DeKemp EM, Beanlands RA, Perisic L, Maegdefessel L, Hedin U, Sad S, Guo L, Kolodgie FD, Virmani R, et al. Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis. Science Advances. 2: e1600224. PMID 27532042 DOI: 10.1126/Sciadv.1600224 |
0.448 |
|
| 2016 |
Shutinoski B, Alturki NA, Rijal D, Bertin J, Gough PJ, Schlossmacher MG, Sad S.. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo. Cell Death Differ.. 10: 1628-37. PMID 27258786 DOI: 10.1038/Cdd.2016.51 |
0.793 |
|
| 2016 |
Huus KE, Joseph J, Zhang L, Wong A, Aaron SD, Mah TF, Sad S. Clinical Isolates of Pseudomonas aeruginosa from Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation. Journal of Immunology (Baltimore, Md. : 1950). PMID 26895832 DOI: 10.4049/Jimmunol.1501642 |
0.41 |
|
| 2016 |
Shutinoski B, Alturki NA, Rijal D, Bertin J, Gough PJ, Schlossmacher MG, Sad S. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo Cell Death and Differentiation. DOI: 10.1038/cdd.2016.51 |
0.791 |
|
| 2015 |
Patel R, Sad S. Transcription factor Batf3 is important for development of CD8(+) T-cell response against a phagosomal bacterium regardless of the location of antigen. Immunology and Cell Biology. PMID 26567886 DOI: 10.1038/Icb.2015.98 |
0.468 |
|
| 2015 |
Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan L, Zafer AA, et al. A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections. Mbio. 6. PMID 26396246 DOI: 10.1128/Mbio.01421-15 |
0.328 |
|
| 2015 |
Arulanandam R, Batenchuk C, Angarita FA, Ottolino-Perry K, Cousineau S, Mottashed A, Burgess E, Falls TJ, De Silva N, Tsang J, Howe GA, Bourgeois-Daigneault MC, Conrad DP, Daneshmand M, Breitbach CJ, ... ... Sad S, et al. VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection. Cancer Cell. 28: 210-24. PMID 26212250 DOI: 10.1016/J.Ccell.2015.06.009 |
0.327 |
|
| 2015 |
Côté S, Matte J, Sad S, Angel JB, Crawley AM. Complexed soluble IL-7 receptor α and IL-7 increase IL-7-mediated proliferation and viability of CD8⁺ T-cells in vitro. Cellular Immunology. 293: 122-5. PMID 25596474 DOI: 10.1016/J.Cellimm.2015.01.001 |
0.382 |
|
| 2014 |
McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S. Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 111: E3206-13. PMID 25049377 DOI: 10.1073/Pnas.1407068111 |
0.778 |
|
| 2014 |
McComb S, Shutinoski B, Thurston S, Cessford E, Kumar K, Sad S. Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase. Journal of Immunology (Baltimore, Md. : 1950). 192: 5671-8. PMID 24799565 DOI: 10.4049/Jimmunol.1303380 |
0.781 |
|
| 2014 |
Shutinoski B, Sad S. The detrimental role of Type I interferon signaling during infection with salmonella typhimurium Bacterial Activation of Type I Interferons. 79-86. DOI: 10.1007/978-3-319-09498-4_7 |
0.764 |
|
| 2013 |
Nguyen T, Robinson N, Allison SE, Coombes BK, Sad S, Krishnan L. IL-10 produced by trophoblast cells inhibits phagosome maturation leading to profound intracellular proliferation of Salmonella enterica Typhimurium. Placenta. 34: 765-74. PMID 23834952 DOI: 10.1016/J.Placenta.2013.06.003 |
0.441 |
|
| 2013 |
Tzelepis F, Joseph J, Haddad EK, Maclean S, Dudani R, Agenes F, Peng SL, Sekaly RP, Sad S. Intrinsic role of FoxO3a in the development of CD8+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 190: 1066-75. PMID 23277488 DOI: 10.4049/Jimmunol.1200639 |
0.445 |
|
| 2012 |
Tzelepis F, Alcon V, Dudani R, Gurnani K, Zafer A, Everson ES, Young KG, Rüssmann H, Krishnan L, Sad S. Modulation of antigenic location converts chronic into acute infection by forcing CD8+ T cell recognition. Cell Reports. 2: 1710-21. PMID 23219554 DOI: 10.1016/J.Celrep.2012.10.024 |
0.443 |
|
| 2012 |
Robinson N, McComb S, Mulligan R, Dudani R, Krishnan L, Sad S. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nature Immunology. 13: 954-62. PMID 22922364 DOI: 10.1038/Ni.2397 |
0.719 |
|
| 2012 |
McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death and Differentiation. 19: 1791-801. PMID 22576661 DOI: 10.1038/Cdd.2012.59 |
0.698 |
|
| 2012 |
Stark FC, Gurnani K, Sad S, Krishnan L. Lack of functional selectin ligand interactions compromises long term tumor protection by CD8+ T cells. Plos One. 7: e32211. PMID 22359671 DOI: 10.1371/Journal.Pone.0032211 |
0.449 |
|
| 2011 |
Young KG, Maclean S, Dudani R, Krishnan L, Sad S. CD8+ T cells primed in the periphery provide time-bound immune-surveillance to the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 187: 1192-200. PMID 21715683 DOI: 10.4049/Jimmunol.1100695 |
0.409 |
|
| 2010 |
McComb S, Mulligan R, Sad S. Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo. Plos One. 5: e15328. PMID 21203525 DOI: 10.1371/Journal.Pone.0015328 |
0.665 |
|
| 2010 |
Chattopadhyay A, Robinson N, Sandhu JK, Finlay BB, Sad S, Krishnan L. Salmonella enterica serovar Typhimurium-induced placental inflammation and not bacterial burden correlates with pathology and fatal maternal disease. Infection and Immunity. 78: 2292-301. PMID 20194592 DOI: 10.1128/Iai.01186-09 |
0.452 |
|
| 2010 |
Krishnan L, Pejcic-Karapetrovic B, Gurnani K, Zafer A, Sad S. Pregnancy does not deter the development of a potent maternal protective CD8+ T-cell acquired immune response against Listeria monocytogenes despite preferential placental colonization. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 63: 54-65. PMID 19912156 DOI: 10.1111/J.1600-0897.2009.00766.X |
0.366 |
|
| 2009 |
Russell MS, Dudani R, Krishnan L, Sad S. IFN-gamma expressed by T cells regulates the persistence of antigen presentation by limiting the survival of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 7710-8. PMID 19923462 DOI: 10.4049/Jimmunol.0901274 |
0.467 |
|
| 2009 |
Wong CE, Sad S, Coombes BK. Salmonella enterica serovar typhimurium exploits Toll-like receptor signaling during the host-pathogen interaction. Infection and Immunity. 77: 4750-60. PMID 19720755 DOI: 10.1128/Iai.00545-09 |
0.467 |
|
| 2009 |
Albaghdadi H, Robinson N, Finlay B, Krishnan L, Sad S. Selectively reduced intracellular proliferation of Salmonella enterica serovar typhimurium within APCs limits antigen presentation and development of a rapid CD8 T cell response. Journal of Immunology (Baltimore, Md. : 1950). 183: 3778-87. PMID 19692639 DOI: 10.4049/Jimmunol.0900843 |
0.515 |
|
| 2009 |
Stark FC, Sad S, Krishnan L. Intracellular bacterial vectors that induce CD8(+) T cells with similar cytolytic abilities but disparate memory phenotypes provide contrasting tumor protection. Cancer Research. 69: 4327-34. PMID 19435919 DOI: 10.1158/0008-5472.Can-08-3160 |
0.416 |
|
| 2008 |
Dudani R, Murali-Krishna K, Krishnan L, Sad S. IFN-gamma induces the erosion of preexisting CD8 T cell memory during infection with a heterologous intracellular bacterium. Journal of Immunology (Baltimore, Md. : 1950). 181: 1700-9. PMID 18641306 DOI: 10.4049/Jimmunol.181.3.1700 |
0.423 |
|
| 2008 |
Sad S, Dudani R, Gurnani K, Russell M, van Faassen H, Finlay B, Krishnan L. Pathogen proliferation governs the magnitude but compromises the function of CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 5853-61. PMID 18424704 DOI: 10.4049/Jimmunol.180.9.5853 |
0.476 |
|
| 2008 |
Dudani R, Russell M, van Faassen H, Krishnan L, Sad S. Mutation in the Fas pathway impairs CD8+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 180: 2933-41. PMID 18292515 DOI: 10.4049/Jimmunol.180.5.2933 |
0.425 |
|
| 2007 |
Pejcic-Karapetrovic B, Gurnani K, Russell MS, Finlay BB, Sad S, Krishnan L. Pregnancy impairs the innate immune resistance to Salmonella typhimurium leading to rapid fatal infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 6088-96. PMID 17947683 DOI: 10.4049/Jimmunol.179.9.6088 |
0.431 |
|
| 2007 |
Russell MS, Iskandar M, Mykytczuk OL, Nash JH, Krishnan L, Sad S. A reduced antigen load in vivo, rather than weak inflammation, causes a substantial delay in CD8+ T cell priming against Mycobacterium bovis (bacillus Calmette-Guérin). Journal of Immunology (Baltimore, Md. : 1950). 179: 211-20. PMID 17579040 DOI: 10.4049/Jimmunol.179.1.211 |
0.464 |
|
| 2007 |
Krishnan L, Gurnani K, Dicaire CJ, van Faassen H, Zafer A, Kirschning CJ, Sad S, Sprott GD. Rapid clonal expansion and prolonged maintenance of memory CD8+ T cells of the effector (CD44highCD62Llow) and central (CD44highCD62Lhigh) phenotype by an archaeosome adjuvant independent of TLR2. Journal of Immunology (Baltimore, Md. : 1950). 178: 2396-406. PMID 17277146 DOI: 10.4049/Jimmunol.178.4.2396 |
0.429 |
|
| 2006 |
Luu RA, Gurnani K, Dudani R, Kammara R, van Faassen H, Sirard JC, Krishnan L, Sad S. Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium. Journal of Immunology (Baltimore, Md. : 1950). 177: 1516-25. PMID 16849458 DOI: 10.4049/Jimmunol.177.3.1516 |
0.481 |
|
| 2006 |
Saito K, Yajima T, Kumabe S, Doi T, Yamada H, Sad S, Shen H, Yoshikai Y. Impaired protection against Mycobacterium bovis bacillus Calmette-Guerin infection in IL-15-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 2496-504. PMID 16456010 DOI: 10.4049/Jimmunol.176.4.2496 |
0.424 |
|
| 2006 |
Winau F, Weber S, Sad S, de Diego J, Hoops SL, Breiden B, Sandhoff K, Brinkmann V, Kaufmann SH, Schaible UE. Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity. 24: 105-17. PMID 16413927 DOI: 10.1016/J.Immuni.2005.12.001 |
0.471 |
|
| 2006 |
Yajima T, Yoshihara K, Nakazato K, Kumabe S, Koyasu S, Sad S, Shen H, Kuwano H, Yoshikai Y. IL-15 regulates CD8+ T cell contraction during primary infection. Journal of Immunology (Baltimore, Md. : 1950). 176: 507-15. PMID 16365444 DOI: 10.4049/Jimmunol.176.1.507 |
0.457 |
|
| 2005 |
van Faassen H, Saldanha M, Gilbertson D, Dudani R, Krishnan L, Sad S. Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset. Journal of Immunology (Baltimore, Md. : 1950). 174: 5341-50. PMID 15843531 DOI: 10.4049/Jimmunol.174.9.5341 |
0.439 |
|
| 2005 |
Yajima T, Nishimura H, Sad S, Shen H, Kuwano H, Yoshikai Y. A novel role of IL-15 in early activation of memory CD8+ CTL after reinfection. Journal of Immunology (Baltimore, Md. : 1950). 174: 3590-7. PMID 15749896 DOI: 10.4049/Jimmunol.174.6.3590 |
0.415 |
|
| 2004 |
Sprott GD, Dicaire CJ, Gurnani K, Sad S, Krishnan L. Activation of dendritic cells by liposomes prepared from phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette-Guerin and adjuvant activity in vivo. Infection and Immunity. 72: 5235-46. PMID 15322018 DOI: 10.1128/Iai.72.9.5235-5246.2004 |
0.391 |
|
| 2004 |
Gurnani K, Kennedy J, Sad S, Sprott GD, Krishnan L. Phosphatidylserine receptor-mediated recognition of archaeosome adjuvant promotes endocytosis and MHC class I cross-presentation of the entrapped antigen by phagosome-to-cytosol transport and classical processing. Journal of Immunology (Baltimore, Md. : 1950). 173: 566-78. PMID 15210818 DOI: 10.4049/Jimmunol.173.1.566 |
0.441 |
|
| 2004 |
van Faassen H, Dudani R, Krishnan L, Sad S. Prolonged antigen presentation, APC-, and CD8+ T cell turnover during mycobacterial infection: comparison with Listeria monocytogenes. Journal of Immunology (Baltimore, Md. : 1950). 172: 3491-500. PMID 15004149 DOI: 10.4049/Jimmunol.172.6.3491 |
0.467 |
|
| 2003 |
Sprott GD, Sad S, Fleming LP, Dicaire CJ, Patel GB, Krishnan L. Archaeosomes varying in lipid composition differ in receptor-mediated endocytosis and differentially adjuvant immune responses to entrapped antigen. Archaea (Vancouver, B.C.). 1: 151-64. PMID 15803661 DOI: 10.1155/2003/569283 |
0.327 |
|
| 2003 |
Chapdelaine Y, Smith DK, Pedras-Vasconcelos JA, Krishnan L, Sad S. Increased CD8+ T cell memory to concurrent infection at the expense of increased erosion of pre-existing memory: the paradoxical role of IL-15. Journal of Immunology (Baltimore, Md. : 1950). 171: 5454-60. PMID 14607951 DOI: 10.4049/Jimmunol.171.10.5454 |
0.393 |
|
| 2003 |
Sad S, Krishnan L. Maintenance and attrition of T-cell memory. Critical Reviews in Immunology. 23: 129-47. PMID 12906263 DOI: 10.1615/Critrevimmunol.V23.I12.70 |
0.411 |
|
| 2003 |
Krishnan L, Sad S, Patel GB, Sprott GD. Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped soluble protein in the absence of interleukin 12 and protect against tumor challenge. Cancer Research. 63: 2526-34. PMID 12750276 |
0.352 |
|
| 2002 |
Smith DK, Dudani R, Pedras-Vasconcelos JA, Chapdelaine Y, van Faassen H, Sad S. Cross-reactive antigen is required to prevent erosion of established T cell memory and tumor immunity: a heterologous bacterial model of attrition. Journal of Immunology (Baltimore, Md. : 1950). 169: 1197-206. PMID 12133940 DOI: 10.4049/Jimmunol.169.3.1197 |
0.451 |
|
| 2002 |
Pedras-Vasconcelos JA, Chapdelaine Y, Dudani R, van Faassen H, Smith DK, Sad S. Mycobacterium bovis BCG-infected mice are more susceptible to staphylococcal enterotoxin B-mediated toxic shock than uninfected mice despite reduced in vitro splenocyte responses to superantigens. Infection and Immunity. 70: 4148-57. PMID 12117923 DOI: 10.1128/Iai.70.8.4148-4157.2002 |
0.485 |
|
| 2002 |
Dudani R, Chapdelaine Y, Faassen Hv Hv, Smith DK, Shen H, Krishnan L, Sad S. Multiple mechanisms compensate to enhance tumor-protective CD8(+) T cell response in the long-term despite poor CD8(+) T cell priming initially: comparison between an acute versus a chronic intracellular bacterium expressing a model antigen. Journal of Immunology (Baltimore, Md. : 1950). 168: 5737-45. PMID 12023374 DOI: 10.4049/Jimmunol.168.11.5737 |
0.453 |
|
| 2002 |
Dudani R, Chapdelaine Y, van Faassen H, Smith DK, Shen H, Krishnan L, Sad S. Preexisting inflammation due to Mycobacterium bovis BCG infection differentially modulates T-cell priming against a replicating or nonreplicating immunogen. Infection and Immunity. 70: 1957-64. PMID 11895959 DOI: 10.1128/Iai.70.4.1957-1964.2002 |
0.425 |
|
| 2001 |
Krishnan L, Sad S, Patel GB, Sprott GD. The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 166: 1885-93. PMID 11160236 DOI: 10.4049/Jimmunol.166.3.1885 |
0.463 |
|
| 2000 |
Krishnan L, Sad S, Patel GB, Sprott GD. Archaeosomes induce long-term CD8+ cytotoxic T cell response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4+ T cell help. Journal of Immunology (Baltimore, Md. : 1950). 165: 5177-85. PMID 11046050 DOI: 10.4049/Jimmunol.165.9.5177 |
0.453 |
|
| 2000 |
Liu T, Guo Z, Yang Q, Sad S, Jennings HJ. Biochemical engineering of surface α2-8 polysialic acid for immunotargeting tumor cells Journal of Biological Chemistry. 275: 32832-32836. PMID 10976100 DOI: 10.1074/Jbc.C000573200 |
0.307 |
|
| 1997 |
Mosmann TR, Li L, Sad S. Functions of CD8 T-cell subsets secreting different cytokine patterns Seminars in Immunology. 9: 87-92. PMID 9194219 DOI: 10.1006/Smim.1997.0065 |
0.486 |
|
| 1997 |
Sad S, Krishnan L, Bleackley RC, Kägi D, Hengartner H, Mosmann TR. Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity. European Journal of Immunology. 27: 914-22. PMID 9130644 DOI: 10.1002/Eji.1830270417 |
0.415 |
|
| 1997 |
Li L, Sad S, Kägi D, Mosmann TR. CD8Tc1 and Tc2 Cells Secrete Distinct Cytokine Patterns in Vitro and in Vivo but Induce Similar Inflammatory Reactions Journal of Immunology. 158: 4152-4161. PMID 9126975 |
0.394 |
|
| 1997 |
Mosmann TR, Li L, Hengartner H, Kagi D, Fu W, Sad S. Differentiation and functions of T cell subsets. Ciba Foundation Symposium. 204: 148-54; discussion 1. PMID 9107418 |
0.36 |
|
| 1996 |
Sad S, Kägi D, Mosmann TR. Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation Journal of Experimental Medicine. 184: 1543-1547. PMID 8879227 DOI: 10.1084/Jem.184.4.1543 |
0.456 |
|
| 1996 |
Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more Immunology Today. 17: 138-146. PMID 8820272 DOI: 10.1016/0167-5699(96)80606-2 |
0.428 |
|
| 1996 |
Mosmanm T, Sad S, Li L, Kagi D, Hengartner H, Bleackley R, Krishnan L, Belosevic M, Guilbert L. Immunoregulation by cytokines of T cell subsets Placenta. 17: A6. DOI: 10.1016/S0143-4004(96)90085-5 |
0.394 |
|
| 1995 |
Mosmann TR, Sad S, Krishnan L, Wegmann TG, Guilbert LJ, Belosevic M. Differentiation of subsets of CD4+ and CD8+ T cells. Ciba Foundation Symposium. 195: 42-50; discussion 50. PMID 8724829 |
0.333 |
|
| 1995 |
Krishnan L, Sad S, Raghupathy R. Characterization of an immunosuppressive factor secreted by a human trophoblast-derived choriocarcinoma cell line. Cellular Immunology. 162: 295-308. PMID 7743558 DOI: 10.1006/Cimm.1995.1082 |
0.389 |
|
| 1995 |
Sad S, Marcotte R, Mosmann TR. Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines Immunity. 2: 271-279. PMID 7697544 DOI: 10.1016/1074-7613(95)90051-9 |
0.392 |
|
| 1995 |
Sad S, Mosmann TR. Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: Loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines Journal of Experimental Medicine. 182: 1505-1515. PMID 7595220 DOI: 10.1084/Jem.182.5.1505 |
0.386 |
|
| 1994 |
Sad S, Marcotte R, Mosmann T. IL4 induces differentiation of cytotoxic CD8+ T cells secreting TH2 cytokines Cytokine. 6: 575. DOI: 10.1016/1043-4666(94)90296-8 |
0.404 |
|
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