| Year |
Citation |
Score |
| 2024 |
Xie X, Macknight HP, Lu AL, Chalfant CE. RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer. Biorxiv : the Preprint Server For Biology. PMID 39026815 DOI: 10.1101/2024.07.08.602494 |
0.304 |
|
| 2019 |
DeLigio JT, Stevens SC, Nazario-Munoz GS, MacKnight HP, Doe KK, Chalfant CE, Park MA. SERINE/ARGININE-RICH SPLICING FACTOR 3 MODULATES THE ALTERNATIVE SPLICING OF CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN 2. Molecular Cancer Research : McR. PMID 31138601 DOI: 10.1158/1541-7786.MCR-18-1291 |
0.301 |
|
| 2017 |
Vhuiyan MI, Pak ML, Park MA, Thomas D, Lakowski TM, Chalfant CE, Frankel A. PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X. Journal of Biochemistry. PMID 28057797 DOI: 10.1093/Jb/Mvw102 |
0.357 |
|
| 2016 |
Shapiro BA, Vu NT, Shultz MD, Shultz JC, Mietla JA, Gouda MM, Yacoub A, Dent P, Fisher PB, Park MA, Chalfant CE. Melanoma differentiation associated gene 7/IL-24 exerts cytotoxic effects by altering the alternative splicing of Bcl-x pre-mRNA via the SRC/PKCδ signaling axis. The Journal of Biological Chemistry. PMID 27519412 DOI: 10.1074/Jbc.M116.737569 |
0.788 |
|
| 2016 |
Vu NT, Park MA, Shultz MD, Bulut GB, Ladd AC, Chalfant CE. Caspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung Tumorigenesis. Cancer Research. 76: 2977-2989. PMID 27197231 DOI: 10.1158/0008-5472.CAN-15-2512 |
0.37 |
|
| 2016 |
McClure MJ, Clark NM, Hyzy SL, Chalfant CE, Olivares-Navarrete R, Boyan BD, Schwartz Z. Role of Integrin α7β1 Signaling in Myoblast Differentiation on Aligned Polydioxanone Scaffolds. Acta Biomaterialia. PMID 27142254 DOI: 10.1016/J.Actbio.2016.04.046 |
0.325 |
|
| 2015 |
Johnson RM, Vu NT, Griffin BP, Gentry AE, Archer KJ, Chalfant CE, Park MA. The alternative splicing of cytoplasmic polyadenylation element binding protein 2 drives anoikis resistance and the metastasis of triple negative breast cancer. The Journal of Biological Chemistry. PMID 26304115 DOI: 10.1074/Jbc.M115.671206 |
0.416 |
|
| 2015 |
Barbour SE, Nguyen PT, Park M, Emani B, Lei X, Kambalapalli M, Shultz JC, Wijesinghe D, Chalfant CE, Ramanadham S. Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells. The Journal of Biological Chemistry. 290: 11021-31. PMID 25762722 DOI: 10.1074/Jbc.M115.648956 |
0.782 |
|
| 2015 |
Vu NT, Park MA, Shultz MD, Ladd AC, Chalfant CE. Abstract LB-023: Caspase-9b directly interacts with cIAP1 to drive agonist-independent NF-κB activation and tumorigenesis in non-small cell lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-023 |
0.438 |
|
| 2014 |
Simanshu DK, Kamlekar RK, Wijesinghe DS, Zou X, Zhai X, Mishra SK, Molotkovsky JG, Malinina L, Hinchcliffe EH, Chalfant CE, Patel DJ, Brown RE. Nonvesicular Trafficking of Ceramide-1-Phosphate by a Lipid Transfer Protein that Regulates Eicosanoid Production Biophysical Journal. 106: 303a. DOI: 10.1016/J.Bpj.2013.11.1759 |
0.33 |
|
| 2013 |
West NW, Garcia-Vargas A, Chalfant CE, Park MA. OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2. Bmc Cancer. 13: 256. PMID 23706161 DOI: 10.1186/1471-2407-13-256 |
0.304 |
|
| 2013 |
Hoeferlin LA, Wijesinghe DS, Chalfant CE. The role of ceramide-1-phosphate in biological functions. Handbook of Experimental Pharmacology. 153-66. PMID 23579454 DOI: 10.1007/978-3-7091-1368-4_8 |
0.313 |
|
| 2013 |
Vu NT, Park MA, Shultz JC, Goehe RW, Hoeferlin LA, Shultz MD, Smith SA, Lynch KW, Chalfant CE. HnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L Journal of Biological Chemistry. 288: 8575-8584. PMID 23396972 DOI: 10.1074/Jbc.M112.443333 |
0.785 |
|
| 2012 |
Norton SK, Wijesinghe DS, Dellinger A, Sturgill J, Zhou Z, Barbour S, Chalfant C, Conrad DH, Kepley CL. Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma. The Journal of Allergy and Clinical Immunology. 130: 761-769.e2. PMID 22664166 DOI: 10.1016/J.Jaci.2012.04.023 |
0.313 |
|
| 2012 |
Shultz JC, Vu N, Shultz MD, Mba MUU, Shapiro BA, Chalfant CE. The proto-oncogene PKCι regulates the alternative splicing of Bcl-x Pre-mRNA Molecular Cancer Research. 10: 660-669. PMID 22522453 DOI: 10.1158/1541-7786.Mcr-11-0363 |
0.806 |
|
| 2012 |
Shultz JC, Chalfant CE. The flip-flop HuR: part of the problem or the solution in fighting cancer? The Journal of Clinical Investigation. 122: 16-9. PMID 22201677 DOI: 10.1172/Jci61677 |
0.761 |
|
| 2011 |
Lamour NF, Wijesinghe DS, Mietla JA, Ward KE, Stahelin RV, Chalfant CE. Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme. The Journal of Biological Chemistry. 286: 42808-17. PMID 22009748 DOI: 10.1074/Jbc.M111.310169 |
0.333 |
|
| 2011 |
Shultz JC, Goehe RW, Murudkar CS, Wijesinghe DS, Mayton EK, Massiello A, Hawkins AJ, Mukerjee P, Pinkerman RL, Park MA, Chalfant CE. SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cells. Molecular Cancer Research : McR. 9: 889-900. PMID 21622622 DOI: 10.1158/1541-7786.Mcr-11-0061 |
0.767 |
|
| 2011 |
Shultz JC, Chalfant CE. Caspase 9b: a new target for therapy in non-small-cell lung cancer. Expert Review of Anticancer Therapy. 11: 499-502. PMID 21504315 DOI: 10.1586/Era.11.23 |
0.747 |
|
| 2010 |
Shultz JC, Goehe RW, Wijesinghe DS, Murudkar C, Hawkins AJ, Shay JW, Minna JD, Chalfant CE. Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a. Cancer Research. 70: 9185-96. PMID 21045158 DOI: 10.1158/0008-5472.Can-10-1545 |
0.772 |
|
| 2010 |
Goehe RW, Shultz JC, Murudkar C, Usanovic S, Lamour NF, Massey DH, Zhang L, Camidge DR, Shay JW, Minna JD, Chalfant CE. hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing. The Journal of Clinical Investigation. 120: 3923-39. PMID 20972334 DOI: 10.1172/Jci43552 |
0.792 |
|
| 2009 |
Lamour NF, Subramanian P, Wijesinghe DS, Stahelin RV, Bonventre JV, Chalfant CE. Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis. The Journal of Biological Chemistry. 284: 26897-907. PMID 19632995 DOI: 10.1074/Jbc.M109.001677 |
0.468 |
|
| 2009 |
Wijesinghe DS, Subramanian P, Lamour NF, Gentile LB, Granado MH, Bielawska A, Szulc Z, Gomez-Munoz A, Chalfant CE. Chain length specificity for activation of cPLA2alpha by C1P: use of the dodecane delivery system to determine lipid-specific effects. Journal of Lipid Research. 50: 1986-95. PMID 19075030 DOI: 10.1194/Jlr.M800367-Jlr200 |
0.487 |
|
| 2007 |
Shultz JC, Chalfant CE. Emetine and the alternative splicing of Bcl-X: where to next? Chemistry & Biology. 14: 1313-4. PMID 18096499 DOI: 10.1016/J.Chembiol.2007.12.002 |
0.781 |
|
| 2007 |
Subramanian P, Vora M, Gentile LB, Stahelin RV, Chalfant CE. Anionic lipids activate group IVA cytosolic phospholipase A2 via distinct and separate mechanisms. Journal of Lipid Research. 48: 2701-8. PMID 17890681 DOI: 10.1194/Jlr.M700356-Jlr200 |
0.526 |
|
| 2007 |
Stahelin RV, Subramanian P, Vora M, Cho W, Chalfant CE. Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain. The Journal of Biological Chemistry. 282: 20467-74. PMID 17472963 DOI: 10.1074/Jbc.M701396200 |
0.508 |
|
| 2007 |
Paronetto MP, Achsel T, Massiello A, Chalfant CE, Sette C. The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x. The Journal of Cell Biology. 176: 929-39. PMID 17371836 DOI: 10.1083/Jcb.200701005 |
0.72 |
|
| 2007 |
Mitra P, Maceyka M, Payne SG, Lamour N, Milstien S, Chalfant CE, Spiegel S. Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells. Febs Letters. 581: 735-40. PMID 17274985 DOI: 10.1016/j.febslet.2007.01.041 |
0.327 |
|
| 2007 |
Ghosh N, Patel N, Jiang K, Watson JE, Cheng J, Chalfant CE, Cooper DR. Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells. Endocrinology. 148: 1359-66. PMID 17158207 DOI: 10.1210/En.2006-0750 |
0.317 |
|
| 2007 |
Payne SG, Oskeritzian CA, Griffiths R, Subramanian P, Barbour SE, Chalfant CE, Milstien S, Spiegel S. The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors. Blood. 109: 1077-85. PMID 17008548 DOI: 10.1182/Blood-2006-03-011437 |
0.56 |
|
| 2006 |
Barnstein BO, Li G, Wang Z, Kennedy S, Chalfant C, Nakajima H, Bunting KD, Ryan JJ. Stat5 expression is required for IgE-mediated mast cell function. Journal of Immunology (Baltimore, Md. : 1950). 177: 3421-6. PMID 16920984 DOI: 10.4049/Jimmunol.177.5.3421 |
0.4 |
|
| 2006 |
Massiello A, Roesser JR, Chalfant CE. SAP155 Binds to ceramide-responsive RNA cis-element 1 and regulates the alternative 5' splice site selection of Bcl-x pre-mRNA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1680-2. PMID 16790528 DOI: 10.1096/Fj.05-5021Fje |
0.72 |
|
| 2006 |
Bandyopadhyay S, Zhan R, Wang Y, Pai SK, Hirota S, Hosobe S, Takano Y, Saito K, Furuta E, Iiizumi M, Mohinta S, Watabe M, Chalfant C, Watabe K. Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells. Cancer Research. 66: 5934-40. PMID 16740734 DOI: 10.1158/0008-5472.Can-05-3197 |
0.411 |
|
| 2006 |
Massiello A, Chalfant CE. SRp30a (ASF/SF2) regulates the alternative splicing of caspase-9 pre-mRNA and is required for ceramide-responsiveness. Journal of Lipid Research. 47: 892-7. PMID 16505493 DOI: 10.1194/jlr.C600003-JLR200 |
0.697 |
|
| 2006 |
Kanj SS, Dandashi N, El-Hed A, Harik H, Maalouf M, Kozhaya L, Mousallem T, Tollefson AE, Wold WS, Chalfant CE, Dbaibo GS. Ceramide regulates SR protein phosphorylation during adenoviral infection. Virology. 345: 280-9. PMID 16271740 DOI: 10.1016/J.Virol.2005.09.060 |
0.359 |
|
| 2005 |
Chalfant CE, Spiegel S. Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling. Journal of Cell Science. 118: 4605-12. PMID 16219683 DOI: 10.1242/Jcs.02637 |
0.356 |
|
| 2005 |
Wijesinghe DS, Massiello A, Subramanian P, Szulc Z, Bielawska A, Chalfant CE. Substrate specificity of human ceramide kinase. Journal of Lipid Research. 46: 2706-16. PMID 16170208 DOI: 10.1194/Jlr.M500313-Jlr200 |
0.684 |
|
| 2005 |
Subramanian P, Stahelin RV, Szulc Z, Bielawska A, Cho W, Chalfant CE. Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2 alpha and enhances the interaction of the enzyme with phosphatidylcholine. The Journal of Biological Chemistry. 280: 17601-7. PMID 15743759 DOI: 10.1074/Jbc.M414173200 |
0.533 |
|
| 2004 |
Patel NA, Apostolatos HS, Mebert K, Chalfant CE, Watson JE, Pillay TS, Sparks J, Cooper DR. Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene. Molecular Endocrinology (Baltimore, Md.). 18: 899-911. PMID 14752056 DOI: 10.1210/Me.2003-0391 |
0.346 |
|
| 2004 |
Massiello A, Salas A, Pinkerman RL, Roddy P, Roesser JR, Chalfant CE. Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide. The Journal of Biological Chemistry. 279: 15799-804. PMID 14734550 DOI: 10.1074/Jbc.M313950200 |
0.709 |
|
| 2004 |
Pettus BJ, Bielawska A, Subramanian P, Wijesinghe DS, Maceyka M, Leslie CC, Evans JH, Freiberg J, Roddy P, Hannun YA, Chalfant CE. Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2. The Journal of Biological Chemistry. 279: 11320-6. PMID 14676210 DOI: 10.1074/Jbc.M309262200 |
0.524 |
|
| 2002 |
Chalfant CE, Rathman K, Pinkerman RL, Wood RE, Obeid LM, Ogretmen B, Hannun YA. De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. The Journal of Biological Chemistry. 277: 12587-95. PMID 11801602 DOI: 10.1074/Jbc.M112010200 |
0.45 |
|
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