Scott McComb, Ph.D. - Publications

Affiliations: 
2013 Biochimie, microbiologie et immunologie / Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
Immunology, Cell Biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Aguadé-Gorgorió J, McComb S, Eckert C, Guinot A, Marovca B, Mezzatesta C, Jenni S, Abduli L, Schrappe M, Dobay MP, Stanulla M, von Stackelberg A, Cario G, Bourquin JP, Bornhauser BC. TNFR2 is required for RIP1-dependent cell death in human leukemia. Blood Advances. 4: 4823-4833. PMID 33027529 DOI: 10.1182/bloodadvances.2019000796  0.473
2020 Bloemberg D, Nguyen T, MacLean S, Zafer A, Gadoury C, Gurnani K, Chattopadhyay A, Ash J, Lippens J, Harcus D, Pagé M, Fortin A, Pon RA, Gilbert R, Marcil A, ... ... McComb S, et al. A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells. Molecular Therapy. Methods & Clinical Development. 16: 238-254. PMID 32083149 DOI: 10.1016/J.Omtm.2020.01.012  0.367
2019 McComb S, Chan PK, Guinot A, Hartmannsdottir H, Jenni S, Dobay MP, Bourquin JP, Bornhauser BC. Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7. Science Advances. 5: eaau9433. PMID 31392262 DOI: 10.1126/Sciadv.Aau9433  0.454
2019 Chopra K, Alasmar S, Zafer A, Huang J, Jezierski A, Mccomb S, Bauman E, Ben RN. Improving The Cryopreservation Of Human Induced Pluripotent Stem Cells (Ipscs) And Human T-Cells With Ice Recrystallization Inhibitors (Iris) Cryobiology. 91: 162. DOI: 10.1016/J.Cryobiol.2019.10.070  0.31
2018 Rijal D, Ariana A, Wight A, Kim K, Alturki NA, Aamir Z, Ametepe E, Korneluk RG, Tiedje C, Menon MB, Gaestel M, McComb S, Sad S. Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1. The Journal of Biological Chemistry. PMID 29899110 DOI: 10.1074/Jbc.Ra118.003614  0.741
2018 Tripolitsioti D, Kumar KS, Neve A, Migliavacca J, Capdeville C, Rushing EJ, Ma M, Kijima N, Sharma A, Pruschy M, McComb S, Taylor MD, Grotzer MA, Baumgartner M. MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells. Oncotarget. 9: 23220-23236. PMID 29796184 DOI: 10.18632/Oncotarget.25294  0.4
2018 Alturki NA, McComb S, Ariana A, Rijal D, Korneluk RG, Sun SC, Alnemri E, Sad S. Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis. Cell Death & Disease. 9: 592. PMID 29789521 DOI: 10.1038/S41419-018-0672-0  0.687
2017 Jordi M, Marty J, Mordasini V, Lünemann A, McComb S, Bernasconi M, Nadal D. IRAK4 is essential for TLR9-induced suppression of Epstein-Barr virus BZLF1 transcription in Akata Burkitt's lymphoma cells. Plos One. 12: e0186614. PMID 29088270 DOI: 10.1371/Journal.Pone.0186614  0.462
2017 Aguadé-Gorgorio J, McComb S, Eckert C, Dobay MP, Cario G, Mezzatesta C, Stackelberg AV, Stanulla M, Martin S, Bourquin J, Bornhauser BC. Abstract 4321: TNF receptor 2 is essential for RIP1-dependent cell death in refractory leukemia Cancer Research. 77: 4321-4321. DOI: 10.1158/1538-7445.Am2017-4321  0.481
2017 Aguadé-Gorgorió J, McComb S, Dobay M, Mezzatesta C, Cario G, Eckert C, Stackelberg Av, Stanulla M, Schrappe M, Bourquin J, Bornhauser B. Die another way: necroptosis as alternative route to cell death Klinische Padiatrie. 229. DOI: 10.1055/S-0037-1602216  0.404
2016 McComb S, Aguadé-Gorgorió J, Harder L, Marovca B, Cario G, Eckert C, Schrappe M, Stanulla M, von Stackelberg A, Bourquin JP, Bornhauser BC. Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL. Science Translational Medicine. 8: 339ra70. PMID 27194728 DOI: 10.1126/Scitranslmed.Aad2986  0.451
2016 Aguadé-Gorgorió J, McComb S, Cario G, Stanulla M, Eckert C, Bourquin J, Bornhauser BC. Abstract 3548:In vivoCRISPR reveals dual activation of apoptosis and necroptosis as means to eradicate drug resistant leukemia Cancer Research. 76: 3548-3548. DOI: 10.1158/1538-7445.Am2016-3548  0.467
2015 McComb S, Aguadé-Gorgorió J, Marovca B, Harder L, Cario G, Eckert C, Schrappe M, Stanulla M, von Stackelberg A, Bourquin J, Bornhauser B. Activation of Simultaneous Apoptosis and Necroptosis to Eradicate Drug Resistant Leukemia Blood. 126: 1283-1283. DOI: 10.1182/Blood.V126.23.1283.1283  0.483
2014 McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S. Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 111: E3206-13. PMID 25049377 DOI: 10.1073/Pnas.1407068111  0.668
2014 McComb S, Shutinoski B, Thurston S, Cessford E, Kumar K, Sad S. Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase. Journal of Immunology (Baltimore, Md. : 1950). 192: 5671-8. PMID 24799565 DOI: 10.4049/Jimmunol.1303380  0.68
2013 McComb S, Thiriot A, Krishnan L, Stark F. Introduction to the immune system. Methods in Molecular Biology (Clifton, N.J.). 1061: 1-20. PMID 23963928 DOI: 10.1007/978-1-62703-589-7_1  0.308
2012 Robinson N, McComb S, Mulligan R, Dudani R, Krishnan L, Sad S. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nature Immunology. 13: 954-62. PMID 22922364 DOI: 10.1038/Ni.2397  0.707
2012 McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death and Differentiation. 19: 1791-801. PMID 22576661 DOI: 10.1038/Cdd.2012.59  0.736
2010 McComb S, Mulligan R, Sad S. Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo. Plos One. 5: e15328. PMID 21203525 DOI: 10.1371/Journal.Pone.0015328  0.59
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