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Rajendra Uprety, Ph.D. - Publications

Affiliations: 
2013 Chemistry North Carolina State University, Raleigh, NC 
Area:
Biochemistry, Microbiology Biology
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12/32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Luo J, Arbely E, Zhang J, Chou C, Uprety R, Chin JW, Deiters A. Genetically encoded optical activation of DNA recombination in human cells. Chemical Communications (Cambridge, England). PMID 27277957 DOI: 10.1039/C6Cc03934K  0.791
2015 Hemphill J, Liu Q, Uprety R, Samanta S, Tsang M, Juliano RL, Deiters A. Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides. Journal of the American Chemical Society. 137: 3656-62. PMID 25734836 DOI: 10.1021/Jacs.5B00580  0.749
2014 Luo J, Uprety R, Naro Y, Chou C, Nguyen DP, Chin JW, Deiters A. Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation. Journal of the American Chemical Society. 136: 15551-8. PMID 25341086 DOI: 10.1021/Ja5055862  0.763
2014 Uprety R, Luo J, Liu J, Naro Y, Samanta S, Deiters A. Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells Chembiochem. 15: 1793-1799. PMID 24976145 DOI: 10.1002/Cbic.201400073  0.738
2014 Engelke H, Chou C, Uprety R, Jess P, Deiters A. Control of protein function through optochemical translocation. Acs Synthetic Biology. 3: 731-6. PMID 24933258 DOI: 10.1021/Sb400192A  0.818
2014 Hemphill J, Govan J, Uprety R, Tsang M, Deiters A. Site-specific promoter caging enables optochemical gene activation in cells and animals. Journal of the American Chemical Society. 136: 7152-8. PMID 24802207 DOI: 10.1021/Ja500327G  0.76
2013 Govan JM, Uprety R, Thomas M, Lusic H, Lively MO, Deiters A. Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. Acs Chemical Biology. 8: 2272-82. PMID 23915424 DOI: 10.1021/Cb400293E  0.705
2012 Connelly CM, Uprety R, Hemphill J, Deiters A. Spatiotemporal control of microRNA function using light-activated antagomirs. Molecular Biosystems. 8: 2987-93. PMID 22945263 DOI: 10.1039/C2Mb25175B  0.724
2012 Govan JM, Uprety R, Hemphill J, Lively MO, Deiters A. Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells. Acs Chemical Biology. 7: 1247-56. PMID 22540192 DOI: 10.1021/Cb300161R  0.763
2011 Chou C, Uprety R, Davis L, Chin JW, Deiters A. Genetically encoding an aliphatic diazirine for protein photocrosslinking Chemical Science. 2: 480-483. DOI: 10.1039/C0Sc00373E  0.804
2010 Hancock SM, Uprety R, Deiters A, Chin JW. Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair. Journal of the American Chemical Society. 132: 14819-24. PMID 20925334 DOI: 10.1021/Ja104609M  0.583
2010 Lusic H, Uprety R, Deiters A. Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite. Organic Letters. 12: 916-9. PMID 20112966 DOI: 10.1021/Ol902807Q  0.744
Low-probability matches (unlikely to be authored by this person)
2014 Reschke ML, Uprety R, Bodhinayake I, Banu M, Boockvar JA, Sauve AA. Multifunctionalization of cetuximab with bioorthogonal chemistries and parallel EGFR profiling of cell-lines using imaging, FACS and immunoprecipitation approaches. Biochimica Et Biophysica Acta. 1844: 2182-2192. PMID 25091197 DOI: 10.1016/j.bbapap.2014.07.017  0.165
2020 Grinnell SG, Uprety R, Varadi A, Subrath J, Hunkele A, Pan YX, Pasternak GW, Majumdar S. Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain. Cellular and Molecular Neurobiology. PMID 32424771 DOI: 10.1007/S10571-020-00867-6  0.146
2018 Uprety R, Váradi A, Allaoa A, Redel-Traub GN, Palmer TC, Feinberg EN, Ferris AC, Pande VS, Pasternak GW, Majumdar S. Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ) receptor selective ligands. European Journal of Medicinal Chemistry. 164: 241-251. PMID 30597325 DOI: 10.1016/J.Ejmech.2018.12.048  0.133
2021 Uprety R, Che T, Zaidi SA, Grinnell SG, Varga BR, Faouzi A, Slocum ST, Allaoa A, Varadi A, Nelson M, Bernhard SM, Kulko E, LeRouzic V, Eans SO, Simons CA, et al. Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site. Elife. 10. PMID 33555255 DOI: 10.7554/eLife.56519  0.113
2021 Zarkin A, Jahan R, Uprety R, Zhang Y, McElhinny C, Snyder R, Gay E, Jewula G, Bool H, Clark SD, Runyon S. Identification of a Novel Neuropeptide S Receptor Antagonist Scaffold Based on the SHA-68 Core. Pharmaceuticals (Basel, Switzerland). 14. PMID 34681248 DOI: 10.3390/ph14101024  0.102
2019 Kruegel AC, Uprety R, Grinnell SG, Langreck C, Pekarskaya EA, Le Rouzic V, Ansonoff M, Gassaway MM, Pintar JE, Pasternak GW, Javitch JA, Majumdar S, Sames D. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. Acs Central Science. 5: 992-1001. PMID 31263758 DOI: 10.1021/Acscentsci.9B00141  0.101
2018 Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011  0.097
2020 Faouzi A, Uprety R, Gomes I, Massaly N, Keresztes AI, Le Rouzic V, Gupta A, Zhang T, Yoon HJ, Ansonoff M, Allaoa A, Pan YX, Pintar J, Morón JA, Streicher JM, et al. Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. Journal of Medicinal Chemistry. PMID 33170687 DOI: 10.1021/acs.jmedchem.0c00901  0.097
2023 Tibbs GR, Uprety R, Warren JD, Beyer NP, Joyce RL, Ferrer MA, Mellado W, Wong VSC, Goldberg DC, Cohen MW, Costa CJ, Li Z, Zhang G, Dephoure NE, Barman DN, et al. An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model. British Journal of Anaesthesia. PMID 37567808 DOI: 10.1016/j.bja.2023.06.067  0.083
2021 Chakraborty S, Uprety R, Daibani AE, Rouzic VL, Hunkele A, Appourchaux K, Eans SO, Nuthikattu N, Jilakara R, Thammavong L, Pasternak GW, Pan YX, McLaughlin JP, Che T, Majumdar S. Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom. Acs Chemical Neuroscience. PMID 34213886 DOI: 10.1021/acschemneuro.1c00149  0.067
2017 Baumann MH, Majumdar S, Le Rouzic V, Hunkele A, Uprety R, Huang XP, Xu J, Roth BL, Pan YX, Pasternak GW. Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace. Neuropharmacology. PMID 28807672 DOI: 10.1016/J.Neuropharm.2017.08.016  0.066
2019 Gutridge AM, Robins MT, Cassell RJ, Uprety R, Mores KL, Ko MJ, Pasternak GW, Majumdar S, van Rijn RM. G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder. British Journal of Pharmacology. PMID 31705528 DOI: 10.1111/Bph.14913  0.065
2021 Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, et al. Oxidative Metabolism as a Modulator of Kratom's Biological Actions. Journal of Medicinal Chemistry. PMID 34783240 DOI: 10.1021/acs.jmedchem.1c01111  0.053
1970 Uprety R. Chemical research should be a national priority Himalayan Journal of Sciences. 2: 10. DOI: 10.3126/hjs.v2i3.220  0.047
2020 Atigari DV, Paton KF, Uprety R, Váradi A, Alder AF, Scouller B, Miller JH, Majumdar S, Kivell BM. The mixed kappa and delta opioid receptor agonist, MP1104, attenuates chemotherapy-induced neuropathic pain. Neuropharmacology. 108445. PMID 33383089 DOI: 10.1016/j.neuropharm.2020.108445  0.034
2015 Khera A, Uprety R, Baniah BB. Self directed integrity assessment of non-piggable pipelines Asme 2015 India International Oil and Gas Pipeline Conference, Iogpc 2015. DOI: 10.1115/IOGPC2015-7949  0.034
2020 Ulker E, Toma W, White A, Uprety R, Majumdar S, Damaj MI. The antinociceptive effects of a dual kappa-delta opioid receptor agonist in the mouse formalin test. Behavioural Pharmacology. 31: 174-178. PMID 32168026 DOI: 10.1097/Fbp.0000000000000541  0.027
2021 Wilson LL, Chakraborty S, Eans SO, Cirino TJ, Stacy HM, Simons CA, Uprety R, Majumdar S, McLaughlin JP. Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal. Cellular and Molecular Neurobiology. PMID 33433723 DOI: 10.1007/s10571-020-01034-7  0.025
2019 Atigari DV, Uprety R, Pasternak GW, Majumdar S, Kivell BM. MP1104, a mixed kappa-delta opioid receptor agonist has anti-cocaine properties with reduced side-effects in rats. Neuropharmacology. PMID 30768946 DOI: 10.1016/J.Neuropharm.2019.02.010  0.019
1970 Uprety R. Menacing food commodities Himalayan Journal of Sciences. 1: 75. DOI: 10.3126/hjs.v1i2.197  0.01
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