Year |
Citation |
Score |
2023 |
Szwabowski GL, Cole JA, Baker DL, Parrill AL. Structure-based pharmacophore modeling 1. Automated random pharmacophore model generation. Journal of Molecular Graphics & Modelling. 108429. PMID 36804368 DOI: 10.1016/j.jmgm.2023.108429 |
0.323 |
|
2021 |
Thomas BN, Parrill AL, Baker DL. Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes: Impact of ligand type and receptor activation state. Journal of Molecular Graphics & Modelling. 112: 108119. PMID 34979368 DOI: 10.1016/j.jmgm.2021.108119 |
0.313 |
|
2020 |
Banerjee S, Norman DD, Deng S, Fakayode SO, Lee SC, Parrill AL, Li W, Miller DD, Tigyi GJ. Molecular modelling guided design, synthesis and QSAR analysis of new small molecule non-lipid autotaxin inhibitors. Bioorganic Chemistry. 103: 104188. PMID 32890995 DOI: 10.1016/J.Bioorg.2020.104188 |
0.496 |
|
2020 |
Szwabowski GL, Castleman PN, Sears CK, Wink LH, Cole JA, Baker DL, Parrill AL. Benchmarking GPCR homology model template selection in combination with de novo loop generation. Journal of Computer-Aided Molecular Design. PMID 32737667 DOI: 10.1007/S10822-020-00325-X |
0.426 |
|
2020 |
Morstein J, Dacheux MA, Norman DD, Shemet A, Donthamsetti PC, Citir M, Frank J, Schultz C, Isacoff EY, Parrill AL, Tigyi GJ, Trauner D. Optical Control of Lysophosphatidic Acid Signaling. Journal of the American Chemical Society. PMID 32469525 DOI: 10.1021/Jacs.0C02154 |
0.408 |
|
2019 |
Wink LH, Baker DL, Cole JA, Parrill AL. A benchmark study of loop modeling methods applied to G protein-coupled receptors. Journal of Computer-Aided Molecular Design. PMID 31123958 DOI: 10.1007/S10822-019-00196-X |
0.396 |
|
2019 |
Morstein J, Hill RZ, Novak AJE, Feng S, Norman DD, Donthamsetti PC, Frank JA, Harayama T, Williams BM, Parrill AL, Tigyi GJ, Riezman H, Isacoff EY, Bautista DM, Trauner D. Optical control of sphingosine-1-phosphate formation and function. Nature Chemical Biology. PMID 31036923 DOI: 10.1038/S41589-019-0269-7 |
0.34 |
|
2018 |
Castleman PN, Sears CK, Cole JA, Baker DL, Parrill AL. GPCR homology model template selection benchmarking: Global versus local similarity measures. Journal of Molecular Graphics & Modelling. 86: 235-246. PMID 30390544 DOI: 10.1016/J.Jmgm.2018.10.016 |
0.393 |
|
2017 |
Banerjee S, Norman DD, Lee SC, Parrill AL, Pham TC, Baker DL, Tigyi GG, Miller DD. Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. Journal of Medicinal Chemistry. PMID 28112925 DOI: 10.1021/Acs.Jmedchem.6B01270 |
0.673 |
|
2016 |
Ragle LE, Palanisamy DJ, Joe MJ, Stein RS, Norman DD, Tigyi G, Baker DL, Parrill AL. Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition. Bioorganic & Medicinal Chemistry. PMID 27544588 DOI: 10.1016/J.Bmc.2016.08.004 |
0.501 |
|
2016 |
Parrill AL. Reprint of: "Synthetic lipids and their role in defining macromolecular assemblies". Chemistry and Physics of Lipids. 194: 149-57. PMID 26496150 DOI: 10.1016/J.Chemphyslip.2015.10.005 |
0.31 |
|
2015 |
Parrill AL. Synthetic lipids and their role in defining macromolecular assemblies. Chemistry and Physics of Lipids. 191: 38-47. PMID 26248325 DOI: 10.1016/J.Chemphyslip.2015.07.024 |
0.31 |
|
2014 |
McMillan JE, Bukiya AN, Terrell CL, Patil SA, Miller DD, Dopico AM, Parrill AL. Multi-generational pharmacophore modeling for ligands to the cholane steroid-recognition site in the β₁ modulatory subunit of the BKCa channel. Journal of Molecular Graphics & Modelling. 54: 174-83. PMID 25459769 DOI: 10.1016/J.Jmgm.2014.10.008 |
0.357 |
|
2014 |
Fells JI, Lee SC, Norman DD, Tsukahara R, Kirby JR, Nelson S, Seibel W, Papoian R, Patil R, Miller DD, Parrill AL, Pham TC, Baker DL, Bittman R, Tigyi G. Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif. The Febs Journal. 281: 1017-28. PMID 24314137 DOI: 10.1111/Febs.12674 |
0.816 |
|
2013 |
Norman DD, Ibezim A, Scott WE, White S, Parrill AL, Baker DL. Autotaxin inhibition: development and application of computational tools to identify site-selective lead compounds. Bioorganic & Medicinal Chemistry. 21: 5548-60. PMID 23816044 DOI: 10.1016/J.Bmc.2013.05.061 |
0.441 |
|
2013 |
Fells JI, Lee SC, Fujiwara Y, Norman DD, Lim KG, Tsukahara R, Liu J, Patil R, Miller DD, Kirby RJ, Nelson S, Seibel W, Papoian R, Parrill AL, Baker DL, et al. Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface. Molecular Pharmacology. 84: 415-24. PMID 23793291 DOI: 10.1124/Mol.113.087080 |
0.776 |
|
2013 |
Young JK, Clayton BT, Kikonyogo A, Pham TC, Parrill AL. Structural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint. International Journal of Molecular Sciences. 14: 2788-807. PMID 23434648 DOI: 10.3390/Ijms14022788 |
0.793 |
|
2013 |
Parrill AL. Computational design and experimental characterization of GPCR segment models. Methods in Enzymology. 522: 81-95. PMID 23374181 DOI: 10.1016/B978-0-12-407865-9.00005-4 |
0.375 |
|
2013 |
Parrill AL, Tigyi G. Integrating the puzzle pieces: the current atomistic picture of phospholipid-G protein coupled receptor interactions. Biochimica Et Biophysica Acta. 1831: 2-12. PMID 22982815 DOI: 10.1016/J.Bbalip.2012.09.002 |
0.448 |
|
2012 |
Parrill AL. Comparative modeling of lipid receptors. Methods in Molecular Biology (Clifton, N.J.). 914: 207-18. PMID 22976030 DOI: 10.1007/978-1-62703-023-6_12 |
0.47 |
|
2012 |
Kiss GN, Fells JI, Gupte R, Lee SC, Liu J, Nusser N, Lim KG, Ray RM, Lin FT, Parrill AL, Sümegi B, Miller DD, Tigyi G. Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions. Molecular Pharmacology. 82: 1162-73. PMID 22968304 DOI: 10.1124/Mol.112.079699 |
0.773 |
|
2012 |
Parrill AL, Lima S, Spiegel S. Structure of the first sphingosine 1-phosphate receptor. Science Signaling. 5: pe23. PMID 22623751 DOI: 10.1126/Scisignal.2003160 |
0.439 |
|
2012 |
Singh AK, Bukiya AN, Parrill AL, Dopico AM. The CRAC Motif Nearest to the N-End of Slo1 Cytosolic C-Tail is the Main Determinant of BK Channel Sensitivity to Membrane Cholesterol Biophysical Journal. 102: 133a. DOI: 10.1016/J.Bpj.2011.11.739 |
0.308 |
|
2011 |
Parrill AL, Wanjala IW, Pham TC, Baker DL. Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7. Bmc Biochemistry. 12: 65. PMID 22177013 DOI: 10.1186/1471-2091-12-65 |
0.761 |
|
2011 |
Mize CD, Abbott AM, Gacasan SB, Parrill AL, Baker DL. Ligand-based autotaxin pharmacophore models reflect structure-based docking results. Journal of Molecular Graphics & Modelling. 31: 76-86. PMID 21967734 DOI: 10.1016/J.Jmgm.2011.09.004 |
0.449 |
|
2011 |
Valentine WJ, Godwin VI, Osborne DA, Liu J, Fujiwara Y, Van Brocklyn J, Bittman R, Parrill AL, Tigyi G. FTY720 (Gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P1) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane domain 2. The Journal of Biological Chemistry. 286: 30513-25. PMID 21719706 DOI: 10.1074/Jbc.M111.263442 |
0.761 |
|
2011 |
Gupte R, Patil R, Liu J, Wang Y, Lee SC, Fujiwara Y, Fells J, Bolen AL, Emmons-Thompson K, Yates CR, Siddam A, Panupinthu N, Pham TC, Baker DL, Parrill AL, et al. Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity. Chemmedchem. 6: 922-35. PMID 21465666 DOI: 10.1002/Cmdc.201000425 |
0.819 |
|
2011 |
Parrill AL. Lysophosphatidic acid receptor agonists and antagonists (WO2010051053). Expert Opinion On Therapeutic Patents. 21: 281-6. PMID 21222547 DOI: 10.1517/13543776.2011.539206 |
0.41 |
|
2011 |
Parrill AL, Bautista DL. GPCR conformations: Implications for rational drug design Pharmaceuticals. 4: 7-43. DOI: 10.3390/Ph4010007 |
0.779 |
|
2010 |
Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD. Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. Bioorganic & Medicinal Chemistry Letters. 20: 7525-8. PMID 21051230 DOI: 10.1016/J.Bmcl.2010.09.115 |
0.669 |
|
2010 |
Parrill AL, Baker DL. Autotaxin inhibitors: a perspective on initial medicinal chemistry efforts. Expert Opinion On Therapeutic Patents. 20: 1619-25. PMID 21047298 DOI: 10.1517/13543776.2010.533658 |
0.374 |
|
2010 |
Pi M, Parrill AL, Quarles LD. GPRC6A mediates the non-genomic effects of steroids. The Journal of Biological Chemistry. 285: 39953-64. PMID 20947496 DOI: 10.1074/Jbc.M110.158063 |
0.322 |
|
2010 |
Tsukahara T, Tsukahara R, Fujiwara Y, Yue J, Cheng Y, Guo H, Bolen A, Zhang C, Balazs L, Re F, Du G, Frohman MA, Baker DL, Parrill AL, Uchiyama A, et al. Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid. Molecular Cell. 39: 421-32. PMID 20705243 DOI: 10.1016/J.Molcel.2010.07.022 |
0.456 |
|
2010 |
Valentine WJ, Kiss GN, Liu J, E S, Gotoh M, Murakami-Murofushi K, Pham TC, Baker DL, Parrill AL, Lu X, Sun C, Bittman R, Pyne NJ, Tigyi G. (S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. Cellular Signalling. 22: 1543-53. PMID 20566326 DOI: 10.1016/J.Cellsig.2010.05.023 |
0.679 |
|
2010 |
Fells JI, Tsukahara R, Liu J, Tigyi G, Parrill AL. 2D binary QSAR modeling of LPA3 receptor antagonism. Journal of Molecular Graphics & Modelling. 28: 828-33. PMID 20356772 DOI: 10.1016/J.Jmgm.2010.03.002 |
0.762 |
|
2010 |
North EJ, Howard AL, Wanjala IW, Pham TC, Baker DL, Parrill AL. Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors. Journal of Medicinal Chemistry. 53: 3095-105. PMID 20349977 DOI: 10.1021/Jm901718Z |
0.785 |
|
2010 |
Hoeglund AB, Bostic HE, Howard AL, Wanjala IW, Best MD, Baker DL, Parrill AL. Optimization of a pipemidic acid autotaxin inhibitor. Journal of Medicinal Chemistry. 53: 1056-66. PMID 20041668 DOI: 10.1021/Jm9012328 |
0.785 |
|
2010 |
Hoeglund AB, Howard AL, Wanjala IW, Pham TC, Parrill AL, Baker DL. Characterization of non-lipid autotaxin inhibitors. Bioorganic & Medicinal Chemistry. 18: 769-76. PMID 20005724 DOI: 10.1016/J.Bmc.2009.11.056 |
0.765 |
|
2009 |
Fells JI, Tsukahara R, Liu J, Tigyi G, Parrill AL. Structure-based drug design identifies novel LPA3 antagonists. Bioorganic & Medicinal Chemistry. 17: 7457-64. PMID 19800804 DOI: 10.1016/J.Bmc.2009.09.022 |
0.777 |
|
2009 |
Zhang H, Xu X, Gajewiak J, Tsukahara R, Fujiwara Y, Liu J, Fells JI, Perygin D, Parrill AL, Tigyi G, Prestwich GD. Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo. Cancer Research. 69: 5441-9. PMID 19509223 DOI: 10.1158/0008-5472.Can-09-0302 |
0.775 |
|
2009 |
Williams JR, Khandoga AL, Goyal P, Fells JI, Perygin DH, Siess W, Parrill AL, Tigyi G, Fujiwara Y. Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation. The Journal of Biological Chemistry. 284: 17304-19. PMID 19366702 DOI: 10.1074/Jbc.M109.003194 |
0.813 |
|
2009 |
North EJ, Osborne DA, Bridson PK, Baker DL, Parrill AL. Autotaxin structure-activity relationships revealed through lysophosphatidylcholine analogs. Bioorganic & Medicinal Chemistry. 17: 3433-42. PMID 19345587 DOI: 10.1016/J.Bmc.2009.03.030 |
0.762 |
|
2008 |
Parrill AL, Baker DL. Autotaxin inhibition: challenges and progress toward novel anti-cancer agents. Anti-Cancer Agents in Medicinal Chemistry. 8: 917-23. PMID 19075574 DOI: 10.2174/187152008786847765 |
0.412 |
|
2008 |
Parrill AL. Lysophospholipid interactions with protein targets. Biochimica Et Biophysica Acta. 1781: 540-6. PMID 18501204 DOI: 10.1016/J.Bbalip.2008.04.011 |
0.448 |
|
2008 |
Fells JI, Tsukahara R, Fujiwara Y, Liu J, Perygin DH, Osborne DA, Tigyi G, Parrill AL. Identification of non-lipid LPA3 antagonists by virtual screening. Bioorganic & Medicinal Chemistry. 16: 6207-17. PMID 18467108 DOI: 10.1016/J.Bmc.2008.04.035 |
0.786 |
|
2008 |
Parrill AL. Crystal structures of a second g protein-coupled receptor: triumphs and implications. Chemmedchem. 3: 1021-3. PMID 18409177 DOI: 10.1002/Cmdc.200800070 |
0.412 |
|
2008 |
Valentine WJ, Fells JI, Perygin DH, Mujahid S, Yokoyama K, Fujiwara Y, Tsukahara R, Van Brocklyn JR, Parrill AL, Tigyi G. Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors. The Journal of Biological Chemistry. 283: 12175-87. PMID 18316373 DOI: 10.1074/Jbc.M708847200 |
0.787 |
|
2008 |
Pham TC, Fells JI, Osborne DA, North EJ, Naor MM, Parrill AL. Molecular recognition in the sphingosine 1-phosphate receptor family. Journal of Molecular Graphics & Modelling. 26: 1189-201. PMID 18165127 DOI: 10.1016/J.Jmgm.2007.11.001 |
0.808 |
|
2008 |
Parrill AL, Echols U, Nguyen T, Pham TC, Hoeglund A, Baker DL. Virtual screening approaches for the identification of non-lipid autotaxin inhibitors. Bioorganic & Medicinal Chemistry. 16: 1784-95. PMID 18036821 DOI: 10.1016/J.Bmc.2007.11.018 |
0.815 |
|
2007 |
Deng W, Shuyu E, Tsukahara R, Valentine WJ, Durgam G, Gududuru V, Balazs L, Manickam V, Arsura M, VanMiddlesworth L, Johnson LR, Parrill AL, Miller DD, Tigyi G. The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury. Gastroenterology. 132: 1834-51. PMID 17484878 DOI: 10.1053/J.Gastro.2007.03.038 |
0.32 |
|
2007 |
Naor MM, Walker MD, Van Brocklyn JR, Tigyi G, Parrill AL. Sphingosine 1-phosphate pKa and binding constants: intramolecular and intermolecular influences. Journal of Molecular Graphics & Modelling. 26: 519-28. PMID 17467317 DOI: 10.1016/J.Jmgm.2007.03.004 |
0.365 |
|
2007 |
Pham TC, Kriwacki RW, Parrill AL. Peptide design and structural characterization of a GPCR loop mimetic. Biopolymers. 86: 298-310. PMID 17443712 DOI: 10.1002/Bip.20745 |
0.676 |
|
2007 |
Fujiwara Y, Osborne DA, Walker MD, Wang DA, Bautista DA, Liliom K, Van Brocklyn JR, Parrill AL, Tigyi G. Identification of the hydrophobic ligand binding pocket of the S1P1 receptor. The Journal of Biological Chemistry. 282: 2374-85. PMID 17114791 DOI: 10.1074/Jbc.M609648200 |
0.774 |
|
2006 |
Tsukahara T, Tsukahara R, Yasuda S, Makarova N, Valentine WJ, Allison P, Yuan H, Baker DL, Li Z, Bittman R, Parrill A, Tigyi G. Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma. The Journal of Biological Chemistry. 281: 3398-407. PMID 16321982 DOI: 10.1074/Jbc.M510843200 |
0.594 |
|
2006 |
Durgam GG, Tsukahara R, Makarova N, Walker MD, Fujiwara Y, Pigg KR, Baker DL, Sardar VM, Parrill AL, Tigyi G, Miller DD. Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands. Bioorganic & Medicinal Chemistry Letters. 16: 633-40. PMID 16263282 DOI: 10.1016/J.Bmcl.2005.10.031 |
0.502 |
|
2006 |
Tsukahara T, Tsukahara R, Yasuda S, Makarova N, Valentine WJ, Li Z, Bittman R, Yuan H, Alison P, Parrill A, Baker DL, Tigyi G. Differential Recognition of LPA and Rosiglitazone by PPARγ 1 The Faseb Journal. 20. DOI: 10.1096/Fasebj.20.4.A259 |
0.565 |
|
2005 |
Parrill AL. Structural characteristics of lysophosphatidic acid biological targets Biochemical Society Transactions. 33: 1366-1369. PMID 16246120 DOI: 10.1042/Bst20051366 |
0.41 |
|
2005 |
Fujiwara Y, Sardar V, Tokumura A, Baker D, Murakami-Murofushi K, Parrill A, Tigyi G. Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells. The Journal of Biological Chemistry. 280: 35038-50. PMID 16115890 DOI: 10.1074/Jbc.M504351200 |
0.494 |
|
2005 |
Jo E, Sanna MG, Gonzalez-Cabrera PJ, Thangada S, Tigyi G, Osborne DA, Hla T, Parrill AL, Rosen H. S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate. Chemistry & Biology. 12: 703-15. PMID 15975516 DOI: 10.1016/J.Chembiol.2005.04.019 |
0.771 |
|
2005 |
Inagaki Y, Pham TT, Fujiwara Y, Kohno T, Osborne DA, Igarashi Y, Tigyi G, Parrill AL. Sphingosine 1-phosphate analogue recognition and selectivity at S1P4 within the endothelial differentiation gene family of receptors. The Biochemical Journal. 389: 187-95. PMID 15733055 DOI: 10.1042/BJ20050046 |
0.752 |
|
2005 |
Yuan H, Parrill A. Cluster analysis and three-dimensional QSAR studies of HIV-1 integrase inhibitors. Journal of Molecular Graphics & Modelling. 23: 317-28. PMID 15670952 DOI: 10.1016/J.Jmgm.2004.10.003 |
0.555 |
|
2004 |
Holdsworth G, Osborne DA, Pham TT, Fells JI, Hutchinson G, Milligan G, Parrill AL. A single amino acid determines preference between phospholipids and reveals length restriction for activation of the S1P4 receptor. Bmc Biochemistry. 5: 12. PMID 15298705 DOI: 10.1186/1471-2091-5-12 |
0.817 |
|
2004 |
Parrill AL, Sardar VM, Yuan H. Sphingosine 1-phosphate and lysophosphatidic acid receptors: agonist and antagonist binding and progress toward development of receptor-specific ligands. Seminars in Cell & Developmental Biology. 15: 467-76. PMID 15271292 DOI: 10.1016/J.Semcdb.2004.05.006 |
0.653 |
|
2003 |
Parrill AL. HIV-1 integrase inhibition: Binding sites, structure activity relationships and future perspectives Current Medicinal Chemistry. 10: 1811-1824. PMID 12871106 DOI: 10.2174/0929867033457043 |
0.365 |
|
2003 |
Virag T, Elrod DB, Liliom K, Sardar VM, Parrill AL, Yokoyama K, Durgam G, Deng W, Miller DD, Tigyi G. Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors. Molecular Pharmacology. 63: 1032-42. PMID 12695531 DOI: 10.1124/Mol.63.5.1032 |
0.511 |
|
2002 |
Yuan H, Parrill AL. QSAR studies of HIV-1 integrase inhibition. Bioorganic & Medicinal Chemistry. 10: 4169-83. PMID 12413870 DOI: 10.1016/S0968-0896(02)00332-2 |
0.6 |
|
2002 |
Mishra H, Parrill AL, Williamson JS. Three-dimensional quantitative structure-activity relationship and comparative molecular field analysis of dipeptide hydroxamic acid Helicobacter pylori urease inhibitors. Antimicrobial Agents and Chemotherapy. 46: 2613-8. PMID 12121941 DOI: 10.1128/Aac.46.8.2613-2618.2002 |
0.388 |
|
2002 |
Sardar VM, Bautista DL, Fischer DJ, Yokoyama K, Nusser N, Virag T, Wang DA, Baker DL, Tigyi G, Parrill AL. Molecular basis for lysophosphatidic acid receptor antagonist selectivity. Biochimica Et Biophysica Acta. 1582: 309-17. PMID 12069842 DOI: 10.1016/S1388-1981(02)00185-3 |
0.808 |
|
2001 |
Wang DA, Lorincz Z, Bautista DL, Liliom K, Tigyi G, Parrill AL. A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors. The Journal of Biological Chemistry. 276: 49213-20. PMID 11604399 DOI: 10.1074/Jbc.M107301200 |
0.801 |
|
2001 |
Fischer DJ, Nusser N, Virag T, Yokoyama K, Wang DA, Baker DL, Bautista D, Parrill AL, Tigyi G. Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors Molecular Pharmacology. 60: 776-784. PMID 11562440 |
0.373 |
|
2001 |
Roaten JB, Kazanietz MG, Sweatman TW, Lothstein L, Israel M, Parrill AL. Molecular models of N-benzyladriamycin-14-valerate (AD 198) in complex with the phorbol ester-binding C1b domain of protein kinase C-delta. Journal of Medicinal Chemistry. 44: 1028-34. PMID 11297449 DOI: 10.1021/Jm000289V |
0.34 |
|
2000 |
Parrill AL, Wang D, Bautista DL, Van Brocklyn JR, Lorincz Z, Fischer DJ, Baker DL, Liliom K, Spiegel S, Tigyi G. Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate. The Journal of Biological Chemistry. 275: 39379-84. PMID 10982820 DOI: 10.1074/Jbc.M007680200 |
0.805 |
|
2000 |
Parrill AL, Baker DL, Wang DA, Fischer DJ, Bautista DL, Van Brocklyn J, Spiegel S, Tigyi G. Structural features of EDG1 receptor-ligand complexes revealed by computational modeling and mutagenesis. Annals of the New York Academy of Sciences. 905: 330-9. PMID 10818477 DOI: 10.1111/J.1749-6632.2000.Tb06573.X |
0.787 |
|
2000 |
Tigyi G, Fischer DJ, Baker D, Wang DA, Yue J, Nusser N, Virag T, Zsiros V, Liliom K, Miller D, Parrill A. Pharmacological characterization of phospholipid growth-factor receptors. Annals of the New York Academy of Sciences. 905: 34-53. PMID 10818440 DOI: 10.1111/J.1749-6632.2000.Tb06536.X |
0.425 |
|
2000 |
Yuan H, Parrill AL. QSAR development to describe HIV-1 integrase inhibition Journal of Molecular Structure: Theochem. 529: 273-282. DOI: 10.1016/S0166-1280(00)00553-4 |
0.302 |
|
2000 |
Bautista DL, Baker DL, Wang D, Fischer DJ, Van Brocklyn J, Spiegel S, Tigyi G, Parrill AL. Dynamic modeling of EDG1 receptor structural changes induced by site-directed mutations Journal of Molecular Structure: Theochem. 529: 219-224. DOI: 10.1016/S0166-1280(00)00549-2 |
0.796 |
|
1998 |
Szabo L, Smith BL, McReynolds KD, Parrill AL, Morris ER, Gervay J. Solid Phase Synthesis and Secondary Structural Studies of (1→5) Amide-Linked Sialooligomers Journal of Organic Chemistry. 63: 1074-1078. DOI: 10.1021/Jo971415E |
0.309 |
|
1997 |
Parrill AL, Mamuya N, Dolata DP, Gervay J. Computational studies of sialyllactones: Methods and uses Glycoconjugate Journal. 14: 523-529. PMID 9249154 DOI: 10.1023/A:1018520006315 |
0.367 |
|
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