| Year |
Citation |
Score |
| 2023 |
Khan S, Chakraborty M, Wu F, Chen N, Wang T, Chan YT, Sayad A, Vásquez JDS, Kotlyar M, Nguyen K, Huang Y, Alibhai FJ, Woo M, Li RK, Husain M, ... ... Ohashi PS, et al. B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters. Biorxiv : the Preprint Server For Biology. PMID 38529494 DOI: 10.1101/2023.09.12.556363 |
0.348 |
|
| 2022 |
Lukhele S, Rabbo DA, Guo M, Shen J, Elsaesser HJ, Quevedo R, Carew M, Gadalla R, Snell LM, Mahesh L, Ciudad MT, Snow BE, You-Ten A, Haight J, Wakeham A, ... Ohashi PS, et al. The transcription factor IRF2 drives interferon-mediated CD8 T cell exhaustion to restrict anti-tumor immunity. Immunity. PMID 36370712 DOI: 10.1016/j.immuni.2022.10.020 |
0.365 |
|
| 2022 |
Dimitriou ID, Meiri D, Jitkova Y, Elford AR, Koritzinsky M, Schimmer AD, Ohashi PS, Sonenberg N, Rottapel R. Translational Control by 4E-BP1/2 Suppressor Proteins Regulates Mitochondrial Biosynthesis and Function during CD8 T Cell Proliferation. Journal of Immunology (Baltimore, Md. : 1950). PMID 35667842 DOI: 10.4049/jimmunol.2101090 |
0.323 |
|
| 2022 |
Chung DC, Jacquelot N, Ghaedi M, Warner K, Ohashi PS. Innate Lymphoid Cells: Role in Immune Regulation and Cancer. Cancers. 14. PMID 35565201 DOI: 10.3390/cancers14092071 |
0.359 |
|
| 2022 |
Han S, Liu ZQ, Chung DC, St Paul M, Garcia-Batres CR, Sayad A, Elford AR, Gold MJ, Grimshaw N, Ohashi PS. Overproduction of IFNγ by Cbl-b-deficient CD8+ T cells provides resistance against regulatory T cells and induces potent antitumor immunity. Cancer Immunology Research. PMID 35181779 DOI: 10.1158/2326-6066.CIR-20-0973 |
0.418 |
|
| 2021 |
St Paul M, Saibil SD, Han S, Israni-Winger K, Lien SC, Laister RC, Sayad A, Penny S, Amaria RN, Haydu LE, Garcia-Batres CR, Kates M, Mulder DT, Robert-Tissot C, Gold MJ, ... ... Ohashi PS, et al. Coenzyme A fuels T cell anti-tumor immunity. Cell Metabolism. 33: 2415-2427.e6. PMID 34879240 DOI: 10.1016/j.cmet.2021.11.010 |
0.313 |
|
| 2020 |
Tran CW, Gold MJ, Garcia-Batres C, Tai K, Elford AR, Himmel ME, Elia AJ, Ohashi PS. Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity. Plos One. 15: e0244366. PMID 33382742 DOI: 10.1371/journal.pone.0244366 |
0.342 |
|
| 2020 |
Sacher AG, St Paul M, Paige CJ, Ohashi PS. Cytotoxic CD4 T Cells in Bladder Cancer-A New License to Kill. Cancer Cell. 38: 28-30. PMID 32663467 DOI: 10.1016/J.Ccell.2020.06.013 |
0.33 |
|
| 2020 |
St Paul M, Ohashi PS. The Roles of CD8 T Cell Subsets in Antitumor Immunity. Trends in Cell Biology. PMID 32624246 DOI: 10.1016/j.tcb.2020.06.003 |
0.365 |
|
| 2020 |
Han S, Chung DC, St Paul M, Liu ZQ, Garcia-Batres C, Elford AR, Tran CW, Chapatte L, Ohashi PS. Overproduction of IL-2 by Cbl-b deficient CD4 T cells provides resistance against regulatory T cells. Oncoimmunology. 9: 1737368. PMID 32313719 DOI: 10.1080/2162402X.2020.1737368 |
0.393 |
|
| 2020 |
Lang PA, Crome SQ, Xu HC, Lang KS, Chapatte L, Deenick EK, Grusdat M, Pandyra AA, Pozdeev VI, Wang R, Holderried TAW, Cantor H, Diefenbach A, Elford AR, McIlwain DR, ... ... Ohashi PS, et al. NK Cells Regulate CD8 T Cell Mediated Autoimmunity. Frontiers in Cellular and Infection Microbiology. 10: 36. PMID 32117809 DOI: 10.3389/Fcimb.2020.00036 |
0.632 |
|
| 2020 |
Romero JM, Grünwald BT, Jang GH, Bavi PP, Jhaveri A, Masoomian M, Fischer SE, Zhang A, Denroche RE, Lungu IM, De Luca A, Bartlett JMS, Xu J, Li N, Dhaliwal S, ... ... Ohashi PS, et al. A four-chemokine signature is associated with a T cell-inflamed phenotype in primary and metastatic pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31964786 DOI: 10.1158/1078-0432.Ccr-19-2803 |
0.326 |
|
| 2020 |
St Paul M, Saibil SD, Lien SL, Han S, Sayad A, Mulder D, Garcia-Batres CR, Elford AR, Israni-Winger K, Robert-Tissot C, Zon M, Katz SR, Shaw P, Clarke BA, Bernardini MQ, ... ... Ohashi PS, et al. IL6 induces an IL22+ CD8+ T cell subset with potent antitumor function. Cancer Immunology Research. PMID 31964625 DOI: 10.1158/2326-6066.Cir-19-0521 |
0.312 |
|
| 2019 |
Halaby MJ, Hezaveh K, Lamorte S, Ciudad MT, Kloetgen A, MacLeod BL, Guo M, Chakravarthy A, Medina TDS, Ugel S, Tsirigos A, Bronte V, Munn DH, Pugh TJ, De Carvalho DD, ... ... Ohashi PS, et al. GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment. Science Immunology. 4. PMID 31836669 DOI: 10.1126/Sciimmunol.Aax8189 |
0.308 |
|
| 2019 |
Martin K, Touil R, Kolb Y, Cvijetic G, Murakami K, Israel L, Duraes F, Buffet D, Glück A, Niwa S, Bigaud M, Junt T, Zamurovic N, Smith P, McCoy KD, ... Ohashi PS, et al. Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 31659015 DOI: 10.4049/jimmunol.1900327 |
0.41 |
|
| 2019 |
Warner K, Ohashi PS. ILC regulation of T cell responses in inflammatory diseases and cancer. Seminars in Immunology. 101284. PMID 31383506 DOI: 10.1016/j.smim.2019.101284 |
0.353 |
|
| 2019 |
Toker A, Ohashi PS. Expression of costimulatory and inhibitory receptors in FoxP3 regulatory T cells within the tumor microenvironment: Implications for combination immunotherapy approaches. Advances in Cancer Research. 144: 193-261. PMID 31349899 DOI: 10.1016/bs.acr.2019.05.001 |
0.322 |
|
| 2019 |
Han S, Toker A, Liu ZQ, Ohashi PS. Turning the Tide Against Regulatory T Cells. Frontiers in Oncology. 9: 279. PMID 31058083 DOI: 10.3389/fonc.2019.00279 |
0.386 |
|
| 2019 |
Cox MA, Duncan GS, Lin GHY, Steinberg BE, Yu LX, Brenner D, Buckler LN, Elia AJ, Wakeham AC, Nieman B, Dominguez-Brauer C, Elford AR, Gill KT, Kubli SP, Haight J, ... ... Ohashi PS, et al. Choline acetyltransferase-expressing T cells are required to control chronic viral infection. Science (New York, N.Y.). 363: 639-644. PMID 30733420 DOI: 10.1126/Science.Aau9072 |
0.761 |
|
| 2019 |
Benveniste PM, Nakatsugawa M, Nguyen L, Ohashi PS, Hirano N, Zúñiga-Pflücker JC. In vitro-generated MART-1-specific CD8 T cells display a broader T cell receptor repertoire than naïve ex vivo and tumor infiltrating lymphocytes. Immunology and Cell Biology. PMID 30633397 DOI: 10.1111/imcb.12231 |
0.388 |
|
| 2019 |
Romero JM, Grünwald B, Connor A, Jang GH, Bavi P, Jhaveri A, Masoomian M, Fischer S, Zhang A, Denroche RE, McGaha T, Notta F, Ohashi P, O'Kane G, Wilson J, et al. Abstract 1500: Mediators of CD8+cytotoxic T lymphocyte infiltration in pancreatic cancer Cancer Research. 79: 1500-1500. DOI: 10.1158/1538-7445.Am2019-1500 |
0.406 |
|
| 2018 |
Butler MO, Majeed H, Nelles M, Saibil S, Bonilla L, Boross-Harmer S, Sotov V, Elston S, Ross K, van As B, Le M, Fyrsta M, Lo C, Yam J, Nie J, ... ... Ohashi P, et al. Study of TBI-1301 (NY-ESO-1 specific TCR gene transduced autologous T lymphocytes) in patients with solid tumors. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii441. PMID 32137125 DOI: 10.1093/Annonc/Mdy288.113 |
0.329 |
|
| 2018 |
Saibil SD, St Paul M, Laister RC, Garcia-Batres CR, Israni-Winger K, Elford AR, Grimshaw N, Robert-Tissot C, Roy DG, Jones RG, Nguyen LT, Ohashi PS. Activation of peroxisome proliferator-activated receptors α and δ synergizes with inflammatory signals to enhance adoptive cell therapy. Cancer Research. PMID 30573521 DOI: 10.1158/0008-5472.CAN-17-3053 |
0.395 |
|
| 2018 |
Benveniste PM, Roy S, Nakatsugawa M, Chen ELY, Nguyen L, Millar DG, Ohashi PS, Hirano N, Adams EJ, Zúñiga-Pflücker JC. Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells. Science Immunology. 3. PMID 30552102 DOI: 10.1126/Sciimmunol.Aav4036 |
0.333 |
|
| 2018 |
Dimitriou ID, Lee K, Akpan I, Lind EF, Barr VA, Ohashi PS, Samelson LE, Rottapel R. Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8 T Cell Expansion and Differentiation. Cell Reports. 24: 1123-1135. PMID 30067970 DOI: 10.1016/J.Celrep.2018.06.075 |
0.377 |
|
| 2018 |
Toker A, Nguyen LT, Stone SC, Yang C, Katz SR, Shaw PA, Clarke BA, Ghazarian DA, Al Habeeb AS, Easson AM, Leong W, McCready D, Reedijk M, Guidos CJ, Pugh TJ, ... ... Ohashi PS, et al. Regulatory T cells in ovarian cancer are characterized by a highly activated phenotype distinct from that in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30065096 DOI: 10.1158/1078-0432.Ccr-18-0554 |
0.332 |
|
| 2017 |
Tran CW, Saibil SD, Le Bihan T, Hamilton SR, Lang KS, You H, Lin AE, Garza KM, Elford AR, Tai K, Parsons ME, Wigmore K, Vainberg MG, Penninger JM, Woodgett JR, ... ... Ohashi PS, et al. Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29109121 DOI: 10.4049/Jimmunol.1600396 |
0.3 |
|
| 2017 |
Ono N, Murakami K, Chan O, Hall H, Elford AR, Yen P, Calzascia T, Spencer DM, Ohashi PS, Dhanji S. Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes. Plos One. 12: e0173176. PMID 28257518 DOI: 10.1371/journal.pone.0173176 |
0.356 |
|
| 2017 |
Crome SQ, Nguyen LT, Lopez-Verges S, Yang SY, Martin B, Yam JY, Johnson DJ, Nie J, Pniak M, Yen PH, Milea A, Sowamber R, Katz SR, Bernardini MQ, Clarke BA, ... ... Ohashi PS, et al. A distinct innate lymphoid cell population regulates tumor-associated T cells. Nature Medicine. PMID 28165478 DOI: 10.1038/Nm.4278 |
0.611 |
|
| 2017 |
Hao Z, Sheng Y, Duncan GS, Li WY, Dominguez C, Sylvester J, Su YW, Lin GH, Snow BE, Brenner D, You-Ten A, Haight J, Inoue S, Wakeham A, Elford A, ... ... Ohashi PS, et al. K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Nature Communications. 8: 14003. PMID 28084302 DOI: 10.1038/Ncomms14003 |
0.406 |
|
| 2016 |
Maney SK, Xu HC, Huang J, Pandyra AA, Ehlting C, Aguilar-Valenzuela R, Pozdeev VI, McIlwain DR, Zimmermann A, Bode JG, Hengel H, Kirschning CJ, Kim IR, Hiscott J, Brenner D, ... ... Ohashi PS, et al. RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 1271-1280. PMID 27606466 DOI: 10.1159/000447832 |
0.664 |
|
| 2016 |
Mahe E, Mulder D, Dowar M, Sukhai M, Nguyen L, Ohashi P, Delabie J, Stockley TL, Pugh T, Kamel-Reid S. Abstract 846: Improving T-cell receptor clonotyping of T-cell lymphomas using hybrid-Capture and next-generation sequencing Cancer Research. 76: 846-846. DOI: 10.1158/1538-7445.Am2016-846 |
0.412 |
|
| 2015 |
Ng D, Maître B, Cummings D, Lin A, Ward LA, Rahbar R, Mossman KL, Ohashi PS, Gommerman JL. A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology. Journal of Immunology (Baltimore, Md. : 1950). 195: 4650-9. PMID 26459352 DOI: 10.4049/Jimmunol.1501053 |
0.376 |
|
| 2015 |
Lind EF, Millar DG, Dissanayake D, Savage JC, Grimshaw NK, Kerr WG, Ohashi PS. miR-155 Upregulation in Dendritic Cells Is Sufficient To Break Tolerance In Vivo by Negatively Regulating SHIP1. Journal of Immunology (Baltimore, Md. : 1950). 195: 4632-40. PMID 26447227 DOI: 10.4049/Jimmunol.1302941 |
0.727 |
|
| 2015 |
Itsumi M, Inoue S, Elia AJ, Murakami K, Sasaki M, Lind EF, Brenner D, Harris IS, Chio II, Afzal S, Cairns RA, Cescon DW, Elford AR, Ye J, Lang PA, ... ... Ohashi PS, et al. Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio. Cell Death and Differentiation. PMID 25882048 DOI: 10.1038/Cdd.2015.38 |
0.488 |
|
| 2015 |
Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, ... ... Ohashi PS, et al. Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 3723-34. PMID 25762782 DOI: 10.4049/jimmunol.1402254 |
0.333 |
|
| 2015 |
Xu HC, Huang J, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, et al. Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection. Journal of Virology. 89: 4748-59. PMID 25673724 DOI: 10.1128/Jvi.02976-14 |
0.602 |
|
| 2015 |
Rahbar R, Lin A, Ghazarian M, Yau HL, Paramathas S, Lang PA, Schildknecht A, Elford AR, Garcia-Batres C, Martin B, Berman HK, Leong WL, McCready DR, Reedijk M, Done SJ, ... ... Ohashi PS, et al. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity. Cancer Immunology Research. 3: 184-95. PMID 25527357 DOI: 10.1158/2326-6066.Cir-14-0113 |
0.512 |
|
| 2015 |
Lang PA, Meryk A, Pandyra AA, Brenner D, Brüstle A, Xu HC, Merches K, Lang F, Khairnar V, Sharma P, Funkner P, Recher M, Shaabani N, Duncan GS, Duhan V, ... ... Ohashi PS, et al. Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection. Cell Death and Differentiation. 22: 164-73. PMID 25257173 DOI: 10.1038/Cdd.2014.138 |
0.583 |
|
| 2014 |
Parish IA, Marshall HD, Staron MM, Lang PA, Brüstle A, Chen JH, Cui W, Tsui YC, Perry C, Laidlaw BJ, Ohashi PS, Weaver CT, Kaech SM. Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1. The Journal of Clinical Investigation. 124: 3455-68. PMID 25003188 DOI: 10.1172/Jci66108 |
0.565 |
|
| 2014 |
Xu HC, Grusdat M, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, ... ... Ohashi PS, et al. Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity. Immunity. 40: 949-60. PMID 24909887 DOI: 10.1016/J.Immuni.2014.05.004 |
0.638 |
|
| 2014 |
Dissanayake D, Murakami K, Tran MD, Elford AR, Millar DG, Ohashi PS. Peptide-pulsed dendritic cells have superior ability to induce immune-mediated tissue destruction compared to peptide with adjuvant. Plos One. 9: e92380. PMID 24647761 DOI: 10.1371/Journal.Pone.0092380 |
0.725 |
|
| 2014 |
Grusdat M, McIlwain DR, Xu HC, Pozdeev VI, Knievel J, Crome SQ, Robert-Tissot C, Dress RJ, Pandyra AA, Speiser DE, Lang E, Maney SK, Elford AR, Hamilton SR, Scheu S, ... ... Ohashi PS, et al. IRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV. Cell Death and Differentiation. 21: 1050-60. PMID 24531538 DOI: 10.1038/Cdd.2014.19 |
0.627 |
|
| 2014 |
Brenner D, Brüstle A, Lin GH, Lang PA, Duncan GS, Knobbe-Thomsen CB, St Paul M, Reardon C, Tusche MW, Snow B, Hamilton SR, Pfefferle A, Gilani SO, Ohashi PS, Lang KS, et al. Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1060-5. PMID 24398517 DOI: 10.1073/Pnas.1323166111 |
0.61 |
|
| 2014 |
Lang P, Xu H, Grusdat M, Parish I, Recher M, Elford A, Dhanji S, Shaabani N, Tran C, Dissanayake D, Rahbar R, Ghazarian M, Brustle A, Fine J, Chen P, ... ... Ohashi P, et al. NK cell activity promotes liver damage and chronic viral infection Zeitschrift FüR Gastroenterologie. 52. DOI: 10.1055/S-0033-1361041 |
0.724 |
|
| 2013 |
Dervovic DD, Liang HC, Cannons JL, Elford AR, Mohtashami M, Ohashi PS, Schwartzberg PL, Zúñiga-Pflücker JC. Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch. Journal of Immunology (Baltimore, Md. : 1950). 191: 1704-15. PMID 23851691 DOI: 10.4049/Jimmunol.1300417 |
0.371 |
|
| 2013 |
Johnson DJ, Pao LI, Dhanji S, Murakami K, Ohashi PS, Neel BG. Shp1 regulates T cell homeostasis by limiting IL-4 signals. The Journal of Experimental Medicine. 210: 1419-31. PMID 23797092 DOI: 10.1084/jem.20122239 |
0.381 |
|
| 2013 |
Johnson DJ, Ohashi PS. Molecular programming of steady-state dendritic cells: impact on autoimmunity and tumor immune surveillance. Annals of the New York Academy of Sciences. 1284: 46-51. PMID 23651192 DOI: 10.1111/nyas.12114 |
0.327 |
|
| 2013 |
Crome SQ, Lang PA, Lang KS, Ohashi PS. Natural killer cells regulate diverse T cell responses. Trends in Immunology. 34: 342-9. PMID 23601842 DOI: 10.1016/J.It.2013.03.002 |
0.627 |
|
| 2013 |
Lang KS, Lang PA, Meryk A, Pandyra AA, Boucher LM, Pozdeev VI, Tusche MW, Göthert JR, Haight J, Wakeham A, You-Ten AJ, McIlwain DR, Merches K, Khairnar V, Recher M, ... ... Ohashi PS, et al. Involvement of Toso in activation of monocytes, macrophages, and granulocytes. Proceedings of the National Academy of Sciences of the United States of America. 110: 2593-8. PMID 23359703 DOI: 10.1073/Pnas.1222264110 |
0.552 |
|
| 2013 |
Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, ... Ohashi PS, et al. Reactive oxygen species delay control of lymphocytic choriomeningitis virus. Cell Death and Differentiation. 20: 649-58. PMID 23328631 DOI: 10.1038/Cdd.2012.167 |
0.631 |
|
| 2013 |
Lind EF, Elford AR, Ohashi PS. Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges. Journal of Immunology (Baltimore, Md. : 1950). 190: 1210-6. PMID 23275599 DOI: 10.4049/jimmunol.1202700 |
0.33 |
|
| 2013 |
Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, ... ... Ohashi PS, et al. Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors Journal of Clinical Investigation. 123: 315-328. PMID 23202731 DOI: 10.1172/Jci64180 |
0.725 |
|
| 2013 |
Lin AE, Ebert G, Ow Y, Preston SP, Toe JG, Cooney JP, Scott HW, Sasaki M, Saibil SD, Dissanayake D, Kim RH, Wakeham A, You-Ten A, Shahinian A, Duncan G, ... ... Ohashi PS, et al. ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system. Nature Immunology. 14: 27-33. PMID 23179078 DOI: 10.1038/Ni.2478 |
0.73 |
|
| 2013 |
Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, et al. Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency. The Journal of Allergy and Clinical Immunology. 131: 815-24. PMID 23141740 DOI: 10.1016/J.Jaci.2012.08.050 |
0.533 |
|
| 2013 |
Hamilton SR, Crome SQ, Ohashi PS. Immunological Tolerance-T Cells The Autoimmune Diseases: Fifth Edition. 87-102. DOI: 10.1016/B978-0-12-384929-8.00007-1 |
0.339 |
|
| 2012 |
Brüstle A, Brenner D, Knobbe CB, Lang PA, Virtanen C, Hershenfield BM, Reardon C, Lacher SM, Ruland J, Ohashi PS, Mak TW. The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells. The Journal of Clinical Investigation. 122: 4698-709. PMID 23114599 DOI: 10.1172/JCI63528 |
0.571 |
|
| 2012 |
Chen G, Dimitriou I, Milne L, Lang KS, Lang PA, Fine N, Ohashi PS, Kubes P, Rottapel R. The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activation. Journal of Immunology (Baltimore, Md. : 1950). 189: 2138-50. PMID 22815290 DOI: 10.4049/Jimmunol.1103184 |
0.526 |
|
| 2012 |
Chatterjee S, Seifried L, Feigin ME, Gibbons DL, Scuoppo C, Lin W, Rizvi ZH, Lind E, Dissanayake D, Kurie J, Ohashi P, Muthuswamy SK. Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells. Plos One. 7: e34343. PMID 22529912 DOI: 10.1371/Journal.Pone.0034343 |
0.724 |
|
| 2012 |
McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, ... Ohashi PS, et al. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science (New York, N.Y.). 335: 229-32. PMID 22246778 DOI: 10.1126/Science.1214448 |
0.529 |
|
| 2012 |
Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, ... ... Ohashi PS, et al. The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. The Journal of Experimental Medicine. 209: 173-86. PMID 22213803 DOI: 10.1084/Jem.20111363 |
0.539 |
|
| 2012 |
Wang C, McPherson AJ, Jones RB, Kawamura KS, Lin GH, Lang PA, Ambagala T, Pellegrini M, Calzascia T, Aidarus N, Elford AR, Yue FY, Kremmer E, Kovacs CM, Benko E, ... ... Ohashi PS, et al. Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection. The Journal of Experimental Medicine. 209: 77-91. PMID 22184633 DOI: 10.1084/Jem.20110675 |
0.589 |
|
| 2012 |
Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brüstle A, Fine J, ... ... Ohashi PS, et al. Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: 1210-5. PMID 22167808 DOI: 10.1073/Pnas.1118834109 |
0.801 |
|
| 2011 |
Dissanayake D, Hall H, Berg-Brown N, Elford AR, Hamilton SR, Murakami K, Deluca LS, Gommerman JL, Ohashi PS. Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells. Nature Medicine. 17: 1663-7. PMID 22081022 DOI: 10.1038/Nm.2556 |
0.76 |
|
| 2011 |
Lin AC, Dissanayake D, Dhanji S, Elford AR, Ohashi PS. Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity. Plos One. 6: e23940. PMID 21931625 DOI: 10.1371/Journal.Pone.0023940 |
0.753 |
|
| 2011 |
Dissanayake D, Gronski MA, Lin A, Elford AR, Ohashi PS. Immunological perspective of self versus tumor antigens: insights from the RIP-gp model. Immunological Reviews. 241: 164-79. PMID 21488897 DOI: 10.1111/J.1600-065X.2011.01014.X |
0.76 |
|
| 2011 |
Ramanathan S, Dubois S, Chen XL, Leblanc C, Ohashi PS, Ilangumaran S. Exposure to IL-15 and IL-21 enables autoreactive CD8 T cells to respond to weak antigens and cause disease in a mouse model of autoimmune diabetes. Journal of Immunology (Baltimore, Md. : 1950). 186: 5131-41. PMID 21430227 DOI: 10.4049/jimmunol.1001221 |
0.349 |
|
| 2011 |
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, ... ... Ohashi PS, et al. IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology. Cell. 144: 601-13. PMID 21295337 DOI: 10.1016/J.Cell.2011.01.011 |
0.56 |
|
| 2011 |
Liontos LM, Dissanayake D, Ohashi PS, Weiss A, Dragone LL, McGlade CJ. The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 186: 1923-33. PMID 21220694 DOI: 10.4049/Jimmunol.0903292 |
0.745 |
|
| 2011 |
Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW. 14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1. Proceedings of the National Academy of Sciences of the United States of America. 108: 1555-60. PMID 21205887 DOI: 10.1073/Pnas.1017729108 |
0.641 |
|
| 2011 |
Sukhai MA, Hurren R, Rutledge A, Livak B, Wang X, Seneviratne A, Cusimano MC, Gebbia M, Skrtic M, Sun H, Gronda M, Spagnuolo PA, Urbanus M, Eppert K, Dissanayake D, ... ... Ohashi P, et al. Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production Blood. 118: 61-61. DOI: 10.1182/Blood.V118.21.61.61 |
0.748 |
|
| 2011 |
Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW. 14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1 (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 4, (1555-1560) DOI: 10.1073/pnas.1017729108) Proceedings of the National Academy of Sciences of the United States of America. 108: 6689. DOI: 10.1073/Pnas.1104407108 |
0.526 |
|
| 2011 |
Rahbar R, Lin A, Ghazarian M, Lang P, Elford AR, Suh W, Mak TW, Ohashi PS. PS2-085 Understanding anti-tumor immunity in breast cancer: Characterization the influence of B7-H4 in T cell responses to tumor antigens Cytokine. 56: 86-87. DOI: 10.1016/J.Cyto.2011.07.248 |
0.515 |
|
| 2010 |
Murakami K, Liadis N, Sarmiento J, Elford AR, Woo M, Nguyen LT, Mak TW, Ohashi PS. Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death. European Journal of Immunology. 40: 3372-7. PMID 21110320 DOI: 10.1002/Eji.201040475 |
0.36 |
|
| 2010 |
Nguyen LT, Yen PH, Nie J, Liadis N, Ghazarian D, Al-Habeeb A, Easson A, Leong W, Lipa J, McCready D, Reedijk M, Hogg D, Joshua AM, Quirt I, Messner H, ... ... Ohashi PS, et al. Expansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs). Plos One. 5: e13940. PMID 21085676 DOI: 10.1371/Journal.Pone.0013940 |
0.308 |
|
| 2010 |
Lang PA, Merkler D, Funkner P, Shaabani N, Meryk A, Krings C, Barthuber C, Recher M, Brück W, Häussinger D, Ohashi PS, Lang KS. Oxidized ATP inhibits T-cell-mediated autoimmunity. European Journal of Immunology. 40: 2401-8. PMID 20683833 DOI: 10.1002/Eji.200939838 |
0.605 |
|
| 2010 |
Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, ... ... Ohashi PS, et al. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology (Baltimore, Md.). 52: 25-32. PMID 20578253 DOI: 10.1002/Hep.23640 |
0.567 |
|
| 2010 |
Ramanathan S, Dubois S, Gagnon J, Leblanc C, Mariathasan S, Ferbeyre G, Rottapel R, Ohashi PS, Ilangumaran S. Regulation of cytokine-driven functional differentiation of CD8 T cells by suppressor of cytokine signaling 1 controls autoimmunity and preserves their proliferative capacity toward foreign antigens. Journal of Immunology (Baltimore, Md. : 1950). 185: 357-66. PMID 20519645 DOI: 10.4049/Jimmunol.1000066 |
0.688 |
|
| 2010 |
Deenick EK, Elford AR, Pellegrini M, Hall H, Mak TW, Ohashi PS. c-Rel but not NF-kappaB1 is important for T regulatory cell development. European Journal of Immunology. 40: 677-81. PMID 20082358 DOI: 10.1002/eji.201040298 |
0.338 |
|
| 2010 |
Deenick EK, Po L, Chapatte L, Murakami K, Lu YC, Elford AR, Saibil SD, Ruland J, Gerondakis S, Mak TW, Ohashi PS. c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance. European Journal of Immunology. 40: 867-77. PMID 19950170 DOI: 10.1002/eji.200939445 |
0.403 |
|
| 2010 |
Lin A, Schildknecht A, Nguyen LT, Ohashi PS. Dendritic cells integrate signals from the tumor microenvironment to modulate immunity and tumor growth. Immunology Letters. 127: 77-84. PMID 19778555 DOI: 10.1016/j.imlet.2009.09.003 |
0.349 |
|
| 2010 |
Kishi Y, Higuchi T, Sakamaki Y, Tsubata T, Miller SD, Martin AJ, Getts D, McCarthy D, Luo X, Ohashi P, Dissanayake D, Lind E, Gary R, Völkl S, Mackensen A, et al. Peripheral tolerance and lymphocyte anergy (WS-072) Chairpersons: Takeshi Tsubata, Pamela Ohashi International Immunology. 22. DOI: 10.1093/Intimm/Dxq323 |
0.314 |
|
| 2010 |
deLuca LS, Ng D, Gao Y, Lin A, Dissanayake D, Rahbar R, Ohashi PS, Gommerman JL. PS1-13 LT-βετα-R Signaling in dendritic cells induces a type I IFN response that integrates with CD40-derived signals for cross-priming of CD8+ T cells Cytokine. 52: 19-20. DOI: 10.1016/J.Cyto.2010.07.085 |
0.735 |
|
| 2009 |
Kamizono S, Duncan GS, Seidel MG, Morimoto A, Hamada K, Grosveld G, Akashi K, Lind EF, Haight JP, Ohashi PS, Look AT, Mak TW. Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo. The Journal of Experimental Medicine. 206: 2977-86. PMID 19995955 DOI: 10.1084/jem.20092176 |
0.353 |
|
| 2009 |
Alam MU, Harken JA, Knorn AM, Elford AR, Wigmore K, Ohashi PS, Millar DG. Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage. Journal of Immunology (Baltimore, Md. : 1950). 183: 5728-37. PMID 19812207 DOI: 10.4049/jimmunol.0901288 |
0.32 |
|
| 2009 |
Kim IR, Murakami K, Chen NJ, Saibil SD, Matysiak-Zablocki E, Elford AR, Bonnard M, Benchimol S, Jurisicova A, Yeh WC, Ohashi PS. DNA damage- and stress-induced apoptosis occurs independently of PIDD. Apoptosis : An International Journal On Programmed Cell Death. 14: 1039-49. PMID 19575295 DOI: 10.1007/S10495-009-0375-1 |
0.518 |
|
| 2009 |
Schildknecht A, Probst HC, McCoy KD, Miescher I, Brenner C, Leone DP, Suter U, Ohashi PS, van den Broek M. Antigens expressed by myelinating glia cells induce peripheral cross-tolerance of endogenous CD8+ T cells. European Journal of Immunology. 39: 1505-15. PMID 19462379 DOI: 10.1002/Eji.200839019 |
0.388 |
|
| 2009 |
Lu YC, Kim I, Lye E, Shen F, Suzuki N, Suzuki S, Gerondakis S, Akira S, Gaffen SL, Yeh WC, Ohashi PS. Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines. Journal of Immunology (Baltimore, Md. : 1950). 182: 7212-21. PMID 19454718 DOI: 10.4049/Jimmunol.0802971 |
0.536 |
|
| 2009 |
Pellegrini M, Calzascia T, Elford AR, Shahinian A, Lin AE, Dissanayake D, Dhanji S, Nguyen LT, Gronski MA, Morre M, Assouline B, Lahl K, Sparwasser T, Ohashi PS, Mak TW. Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies. Nature Medicine. 15: 528-36. PMID 19396174 DOI: 10.1038/Nm.1953 |
0.739 |
|
| 2009 |
Lang PA, Cervantes-Barragan L, Verschoor A, Navarini AA, Recher M, Pellegrini M, Flatz L, Bergthaler A, Honda K, Ludewig B, Ohashi PS, Lang KS. Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood. 113: 1045-52. PMID 18971424 DOI: 10.1182/Blood-2007-10-117861 |
0.58 |
|
| 2009 |
Pellegrini M, Calzascia T, Elford AR, Shahinian A, Lin AE, Dissanayake D, Dhanji S, Nguyen LT, Gronski MA, Morre M, Assouline B, Lahl K, Sparwasser T, Ohashi PS, Mak TW. Erratum: Corrigendum: Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies Nature Medicine. 15: 819-819. DOI: 10.1038/Nm0709-819B |
0.677 |
|
| 2008 |
Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, ... ... Ohashi PS, et al. Aggravation of viral hepatitis by platelet-derived serotonin. Nature Medicine. 14: 756-61. PMID 18516052 DOI: 10.1038/Nm1780 |
0.517 |
|
| 2008 |
Calzascia T, Pellegrini M, Lin A, Garza KM, Elford AR, Shahinian A, Ohashi PS, Mak TW. CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 105: 2999-3004. PMID 18287017 DOI: 10.1073/pnas.0712135105 |
0.34 |
|
| 2008 |
Lye E, Dhanji S, Calzascia T, Elford AR, Ohashi PS. IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses. European Journal of Immunology. 38: 870-6. PMID 18286567 DOI: 10.1002/eji.200737429 |
0.307 |
|
| 2008 |
Hall HT, Wilhelm MT, Saibil SD, Mak TW, Flavell RA, Ohashi PS. RIP2 contributes to Nod signaling but is not essential for T cell proliferation, T helper differentiation or TLR responses. European Journal of Immunology. 38: 64-72. PMID 18085666 DOI: 10.1002/Eji.200737393 |
0.377 |
|
| 2007 |
Saibil SD, Deenick EK, Ohashi PS. The sound of silence: modulating anergy in T lymphocytes. Current Opinion in Immunology. 19: 658-64. PMID 17949964 DOI: 10.1016/j.coi.2007.08.005 |
0.359 |
|
| 2007 |
Ford MS, Chen W, Wong S, Li C, Vanama R, Elford AR, Asa SL, Ohashi PS, Zhang L. Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development. European Journal of Immunology. 37: 2234-41. PMID 17578845 DOI: 10.1002/eji.200636991 |
0.382 |
|
| 2007 |
Saibil SD, Jones RG, Deenick EK, Liadis N, Elford AR, Vainberg MG, Baerg H, Woodgett JA, Gerondakis S, Ohashi PS. CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Cθ c-Rel, and protein kinase B Journal of Immunology. 178: 2932-2939. PMID 17312138 DOI: 10.4049/Jimmunol.178.5.2932 |
0.307 |
|
| 2007 |
Lemmers B, Salmena L, Bidère N, Su H, Matysiak-Zablocki E, Murakami K, Ohashi PS, Jurisicova A, Lenardo M, Hakem R, Hakem A. Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling. The Journal of Biological Chemistry. 282: 7416-23. PMID 17213198 DOI: 10.1074/jbc.M606721200 |
0.359 |
|
| 2006 |
Suh WK, Wang S, Duncan GS, Miyazaki Y, Cates E, Walker T, Gajewska BU, Deenick E, Dawicki W, Okada H, Wakeham A, Itie A, Watts TH, Ohashi PS, Jordana M, et al. Generation and characterization of B7-H4/B7S1/B7x-deficient mice. Molecular and Cellular Biology. 26: 6403-11. PMID 16914726 DOI: 10.1128/MCB.00755-06 |
0.305 |
|
| 2006 |
Suzuki N, Suzuki S, Millar DG, Unno M, Hara H, Calzascia T, Yamasaki S, Yokosuka T, Chen NJ, Elford AR, Suzuki J, Takeuchi A, Mirtsos C, Bouchard D, Ohashi PS, et al. A critical role for the innate immune signaling molecule IRAK-4 in T cell activation. Science (New York, N.Y.). 311: 1927-32. PMID 16574867 DOI: 10.1126/science.1124256 |
0.362 |
|
| 2006 |
Gronski MA, Ohashi PS. Tolerance and Autoimmunity: T cells The Autoimmune Diseases. 103-118. DOI: 10.1016/B978-012595961-2/50011-1 |
0.36 |
|
| 2005 |
Chau H, Wong V, Chen NJ, Huang HL, Lin WJ, Mirtsos C, Elford AR, Bonnard M, Wakeham A, You-Ten AI, Lemmers B, Salmena L, Pellegrini M, Hakem R, Mak TW, ... Ohashi P, et al. Cellular FLICE-inhibitory protein is required for T cell survival and cycling. The Journal of Experimental Medicine. 202: 405-13. PMID 16043518 DOI: 10.1084/Jem.20050118 |
0.487 |
|
| 2005 |
Kwon H, Jun HS, Yang Y, Mora C, Mariathasan S, Ohashi PS, Flavell RA, Yoon JW. Development of autoreactive diabetogenic T cells in the thymus of NOD mice. Journal of Autoimmunity. 24: 11-23. PMID 15725572 DOI: 10.1016/J.Jaut.2004.10.002 |
0.666 |
|
| 2005 |
Krawczyk CM, Jones RG, Atfteld A, Bachmaier K, Arya S, Odermatt B, Ohashi PS, Penninger JM. Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b Journal of Immunology. 174: 1472-1478. PMID 15661906 DOI: 10.4049/Jimmunol.174.3.1472 |
0.316 |
|
| 2004 |
Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS. TCR affinity and negative regulation limit autoimmunity. Nature Medicine. 10: 1234-9. PMID 15467726 DOI: 10.1038/Nm1114 |
0.346 |
|
| 2004 |
Jeon MS, Atfield A, Venuprasad K, Krawczyk C, Sarao R, Elly C, Yang C, Arya S, Bachmaier K, Su L, Bouchard D, Jones R, Gronski M, Ohashi P, Wada T, et al. Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction Immunity. 21: 167-177. PMID 15308098 DOI: 10.1016/J.Immuni.2004.07.013 |
0.448 |
|
| 2004 |
Suh WK, Tafuri A, Berg-Brown NN, Shahinian A, Plyte S, Duncan GS, Okada H, Wakeham A, Odermatt B, Ohashi PS, Mak TW. The Inducible Costimulator Plays the Major Costimulatory Role in Humoral Immune Responses in the Absence of CD28 Journal of Immunology. 172: 5917-5923. PMID 15128772 |
0.34 |
|
| 2004 |
Schmitt TM, de Pooter RF, Gronski MA, Cho SK, Ohashi PS, Zúñiga-Pflücker JC. Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nature Immunology. 5: 410-7. PMID 15034575 DOI: 10.1038/Ni1055 |
0.337 |
|
| 2004 |
Berg-Brown NN, Gronski MA, Jones RG, Elford AR, Deenick EK, Odermatt B, Littman DR, Ohashi PS. PKCθ Signals Activation versus Tolerance In Vivo Journal of Experimental Medicine. 199: 743-752. PMID 15024044 DOI: 10.1084/Jem.20031022 |
0.341 |
|
| 2003 |
Millar DG, Garza KM, Odermatt B, Elford AR, Ono N, Li Z, Ohashi PS. Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo Nature Medicine. 9: 1469-1476. PMID 14625545 DOI: 10.1038/nm962 |
0.318 |
|
| 2003 |
Holmberg K, Mariathasan S, Ohteki T, Ohashi PS, Gascoigne NR. TCR binding kinetics measured with MHC class I tetramers reveal a positive selecting peptide with relatively high affinity for TCR. Journal of Immunology (Baltimore, Md. : 1950). 171: 2427-34. PMID 12928390 DOI: 10.4049/Jimmunol.171.5.2427 |
0.614 |
|
| 2003 |
Mak TW, Shahinian A, Yoshinaga SK, Wakeham A, Boucher LM, Pintilie M, Duncan G, Gajewska BU, Gronski M, Eriksson U, Odermatt B, Ho A, Bouchard D, Whorisky JS, Jordana M, ... Ohashi PS, et al. Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses. Nature Immunology. 4: 765-72. PMID 12833154 DOI: 10.1038/ni947 |
0.378 |
|
| 2003 |
Salmena L, Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K, Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, Wakeham A, Bouchard D, Yeh WC, McGlade JC, Ohashi PS, et al. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes & Development. 17: 883-95. PMID 12654726 DOI: 10.1101/gad.1063703 |
0.384 |
|
| 2003 |
Winer S, Tsui H, Lau A, Song A, Li X, Cheung RK, Sampson A, Afifiyan F, Elford A, Jackowski G, Becker DJ, Santamaria P, Ohashi P, Dosch HM. Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive. Nature Medicine. 9: 198-205. PMID 12539039 DOI: 10.1038/Nm818 |
0.423 |
|
| 2002 |
Bertram EM, Tafuri A, Shahinian A, Chan VS, Hunziker L, Recher M, Ohashi PS, Mak TW, Watts TH. Role of ICOS versus CD28 in antiviral immunity. European Journal of Immunology. 32: 3376-85. PMID 12432568 DOI: 10.1002/1521-4141(200212)32:12<3376::AID-IMMU3376>3.0.CO;2-Y |
0.344 |
|
| 2002 |
Jones RG, Elford AR, Parsons MJ, Wu L, Krawczyk CM, Yeh WC, Hakem R, Rottapel R, Woodgett JR, Ohashi PS. CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. The Journal of Experimental Medicine. 196: 335-48. PMID 12163562 DOI: 10.1084/Jem.20020307 |
0.337 |
|
| 2002 |
Ford MS, Young KJ, Zhang Z, Ohashi PS, Zhang L. The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo. The Journal of Experimental Medicine. 196: 261-7. PMID 12119351 DOI: 10.1084/jem.20020029 |
0.374 |
|
| 2002 |
Ohashi PS. T-cell signalling and autoimmunity: molecular mechanisms of disease. Nature Reviews. Immunology. 2: 427-38. PMID 12093009 DOI: 10.1038/nri822 |
0.325 |
|
| 2002 |
Chan VS, Wong C, Ohashi PS. Calcineurin Aalpha plays an exclusive role in TCR signaling in mature but not in immature T cells. European Journal of Immunology. 32: 1223-9. PMID 11981809 DOI: 10.1002/1521-4141(200205)32:5<1223::AID-IMMU1223>3.0.CO;2-5 |
0.39 |
|
| 2002 |
Krawczyk C, Oliveira-dos-Santos A, Sasaki T, Griffiths E, Ohashi PS, Snapper S, Alt F, Penninger JM. Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity. 16: 331-43. PMID 11911819 DOI: 10.1016/S1074-7613(02)00291-1 |
0.323 |
|
| 2002 |
Garza KM, McKall-Faienza KJ, Otheki T, Zakarian A, Odermatt B, Ohashi PS. Enhanced T cell responses contribute to the genetic predisposition of CD8-mediated spontaneous autoimmunity European Journal of Immunology. 32: 885-894. PMID 11870633 DOI: 10.1002/1521-4141(200203)32:3<885::AID-IMMU885>3.0.CO;2-E |
0.385 |
|
| 2001 |
Mariathasan S, Zakarian A, Bouchard D, Michie AM, Zúñiga-Pflücker JC, Ohashi PS. Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection. Journal of Immunology (Baltimore, Md. : 1950). 167: 4966-73. PMID 11673503 DOI: 10.4049/Jimmunol.167.9.4966 |
0.596 |
|
| 2001 |
Griffiths EK, Krawczyk C, Kong YY, Raab M, Hyduk SJ, Bouchard D, Chan VS, Kozieradzki I, Oliveira-Dos-Santos AJ, Wakeham A, Ohashi PS, Cybulsky MI, Rudd CE, Penninger JM. Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science (New York, N.Y.). 293: 2260-3. PMID 11567140 DOI: 10.1126/Science.1063397 |
0.37 |
|
| 2001 |
Parsons MJ, Jones RG, Tsao MS, Odermatt B, Ohashi PS, Woodgett JR. Expression of active protein kinase B in T cells perturbs both T and B cell homeostasis and promotes inflammation. Journal of Immunology (Baltimore, Md. : 1950). 167: 42-8. PMID 11418630 DOI: 10.4049/Jimmunol.167.1.42 |
0.4 |
|
| 2001 |
Suzuki A, Yamaguchi MT, Ohteki T, Sasaki T, Kaisho T, Kimura Y, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi PS, Koyasu S, Penninger JM, Nakano T, et al. T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity. 14: 523-34. PMID 11371355 DOI: 10.1016/S1074-7613(01)00134-0 |
0.389 |
|
| 2001 |
Ruland J, Duncan GS, Elia A, del Barco Barrantes I, Nguyen L, Plyte S, Millar DG, Bouchard D, Wakeham A, Ohashi PS, Mak TW. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell. 104: 33-42. PMID 11163238 DOI: 10.1016/S0092-8674(01)00189-1 |
0.312 |
|
| 2000 |
Garza KM, Chan VS, Ohashi PS. T cell tolerance and autoimmunity. Reviews in Immunogenetics. 2: 2-17. PMID 11324690 |
0.367 |
|
| 2000 |
Watanabe N, Arase H, Onodera M, Ohashi PS, Saito T. The quantity of TCR signal determines positive selection and lineage commitment of T cells Journal of Immunology. 165: 6252-6261. PMID 11086060 |
0.315 |
|
| 2000 |
Krawczyk C, Bachmaier K, Sasaki T, Jones RG, Snapper SB, Bouchard D, Kozieradzki I, Ohashi PS, Alt FW, Penninger JM. Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells. Immunity. 13: 463-73. PMID 11070165 DOI: 10.1016/S1074-7613(00)00046-7 |
0.313 |
|
| 2000 |
Oliveira-Dos-Santos AJ, Matsumoto G, Snow BE, Bai D, Houston FP, Whishaw IQ, Mariathasan S, Sasaki T, Wakeham A, Ohashi PS, Roder JC, Barnes CA, Siderovski DP, Penninger JM. Regulation of T cell activation, anxiety, and male aggression by RGS2. Proceedings of the National Academy of Sciences of the United States of America. 97: 12272-7. PMID 11027316 DOI: 10.1073/Pnas.220414397 |
0.666 |
|
| 2000 |
Ohteki T, Parsons M, Zakarian A, Jones RG, Nguyen LT, Woodgett JR, Ohashi PS. Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. The Journal of Experimental Medicine. 192: 99-104. PMID 10880530 DOI: 10.1084/Jem.192.1.99 |
0.4 |
|
| 2000 |
Garza KM, Chan SM, Suri R, Nguyen LT, Odermatt B, Schoenberger SP, Ohashi PS. Role of antigen-presenting cells in mediating tolerance and autoimmunity Journal of Experimental Medicine. 191: 2021-2027. PMID 10839816 DOI: 10.1084/jem.191.11.2021 |
0.366 |
|
| 2000 |
Jones RG, Parsons M, Bonnard M, Chan VS, Yeh WC, Woodgett JR, Ohashi PS. Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo. The Journal of Experimental Medicine. 191: 1721-34. PMID 10811865 DOI: 10.1084/Jem.191.10.1721 |
0.364 |
|
| 2000 |
Mariathasan S, Ho SS, Zakarian A, Ohashi PS. Degree of ERK activation influences both positive and negative thymocyte selection. European Journal of Immunology. 30: 1060-8. PMID 10760794 DOI: 10.1002/(Sici)1521-4141(200004)30:4<1060::Aid-Immu1060>3.0.Co;2-2 |
0.599 |
|
| 2000 |
Nguyen LT, McKall-Faienza K, Zakarian A, Speiser DE, Mak TW, Ohashi PS. TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions. European Journal of Immunology. 30: 683-8. PMID 10671227 DOI: 10.1002/1521-4141(200002)30:2<683::AID-IMMU683>3.0.CO;2-5 |
0.328 |
|
| 2000 |
Sasaki T, Irie-Sasaki J, Jones RG, Oliveira-Dos-Santos AJ, Stanford WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi PS, Suzuki A, Penninger JM. Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration Science. 287: 1040-4046. PMID 10669416 DOI: 10.1126/Science.287.5455.1040 |
0.327 |
|
| 2000 |
Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, Mariathasan S, Bouchard D, Wakeham A, Itie A, Le J, Ohashi PS, Sarosi I, Nishina H, Lipkowitz S, et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature. 403: 211-6. PMID 10646608 DOI: 10.1038/35003228 |
0.679 |
|
| 1999 |
Bachmann MF, Ohashi PS. The role of T-cell receptor dimerization in T-cell activation Immunology Today. 20: 568-575. PMID 10562708 DOI: 10.1016/S0167-5699(99)01543-1 |
0.345 |
|
| 1999 |
DeBenedette MA, Wen T, Bachmann MF, Ohashi PS, Barber BH, Stocking KL, Peschon JJ, Watts TH. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus Journal of Immunology. 163: 4833-4841. PMID 10528184 |
0.324 |
|
| 1999 |
Mariathasan S, Jones RG, Ohashi PS. Signals involved in thymocyte positive and negative selection Seminars in Immunology. 11: 263-272. PMID 10441212 DOI: 10.1006/Smim.1999.0182 |
0.598 |
|
| 1999 |
Bachmann MF, Speiser DE, Mak TW, Ohashi PS. Absence of co-stimulation and not the intensity of TCR signaling is critical for the induction of T cell unresponsiveness in vivo European Journal of Immunology. 29: 2156-2166. PMID 10427978 DOI: 10.1002/(SICI)1521-4141(199907)29:07<2156::AID-IMMU2156>3.0.CO;2-P |
0.406 |
|
| 1999 |
Bachmann MF, Nitschke L, Krawczyk C, Tedford K, Ohashi PS, Fischer KD, Penninger JM. The guanine-nucleotide exchange factor Vav is a crucial regulator of B cell receptor activation and B cell responses to nonrepetitive antigens. Journal of Immunology (Baltimore, Md. : 1950). 163: 137-42. PMID 10384109 |
0.371 |
|
| 1999 |
Penninger JM, Fischer KD, Sasaki T, Kozieradzki I, Le J, Tedford K, Bachmaier K, Ohashi PS, Bachmann MF. The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation. European Journal of Immunology. 29: 1709-18. PMID 10359126 DOI: 10.1002/(Sici)1521-4141(199905)29:05<1709::Aid-Immu1709>3.0.Co;2-O |
0.418 |
|
| 1999 |
Sebzda E, Mariathasan S, Ohteki T, Jones R, Bachmann MF, Ohashi PS. Selection of the T cell repertoire Annual Review of Immunology. 17: 829-874. PMID 10358775 DOI: 10.1146/Annurev.Immunol.17.1.829 |
0.658 |
|
| 1999 |
Kägi D, Ho A, Odermatt B, Zakarian A, Ohashi PS, Mak TW. TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes. Journal of Immunology (Baltimore, Md. : 1950). 162: 4598-605. PMID 10201999 |
0.313 |
|
| 1998 |
Kong YY, Fischer KD, Bachmann MF, Mariathasan S, Kozieradzki I, Nghiem MP, Bouchard D, Bernstein A, Ohashi PS, Penninger JM. Vav regulates peptide-specific apoptosis in thymocytes. The Journal of Experimental Medicine. 188: 2099-111. PMID 9841924 DOI: 10.1084/Jem.188.11.2099 |
0.642 |
|
| 1998 |
Mariathasan S, Bachmann MF, Bouchard D, Ohteki T, Ohashi PS. Degree of TCR internalization and Ca2+ flux correlates with thymocyte selection. Journal of Immunology (Baltimore, Md. : 1950). 161: 6030-7. PMID 9834085 |
0.621 |
|
| 1998 |
Bachmann MF, Speiser DE, Zakarian A, Ohashi PS. Inhibition of TCR triggering by a spectrum of altered peptide ligands suggests the mechanism for TCR antagonism. European Journal of Immunology. 28: 3110-9. PMID 9808179 DOI: 10.1002/(SICI)1521-4141(199810)28:10<3110::AID-IMMU3110>3.0.CO;2-5 |
0.307 |
|
| 1998 |
Liu Q, Oliveira-Dos-Santos AJ, Mariathasan S, Bouchard D, Jones J, Sarao R, Kozieradzki I, Ohashi PS, Penninger JM, Dumont DJ. The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling. The Journal of Experimental Medicine. 188: 1333-42. PMID 9763612 DOI: 10.1084/Jem.188.7.1333 |
0.659 |
|
| 1998 |
Bachmann MF, Salzmann M, Oxenius A, Ohashi PS. Formation of TCR dimers/trimers as a crucial step for T cell activation European Journal of Immunology. 28: 2571-2579. PMID 9710234 DOI: 10.1002/(SICI)1521-4141(199808)28:08<2571::AID-IMMU2571>3.0.CO;2-T |
0.303 |
|
| 1998 |
Speiser DE, Ohashi PS. Activation of cytotoxic T cells by solid tumours? Cellular and Molecular Life Sciences. 54: 263-271. PMID 9575338 DOI: 10.1007/s000180050148 |
0.31 |
|
| 1998 |
Bachmann MF, Waterhouse P, Speiser DE, McKall-Faienza K, Mak TW, Ohashi PS. Normal responsiveness of CTLA-4-deficient anti-viral cytotoxic T cells Journal of Immunology. 160: 95-100. PMID 9551960 |
0.38 |
|
| 1998 |
Ohteki T, Yoshida H, Matsuyama T, Duncan GS, Mak TW, Ohashi PS. The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells. The Journal of Experimental Medicine. 187: 967-72. PMID 9500799 DOI: 10.1084/jem.187.6.967 |
0.336 |
|
| 1998 |
Yoshida H, Nishina H, Takimoto H, Marengère LE, Wakeham AC, Bouchard D, Kong YY, Ohteki T, Shahinian A, Bachmann M, Ohashi PS, Penninger JM, Crabtree GR, Mak TW. The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity. 8: 115-24. PMID 9462517 DOI: 10.1016/S1074-7613(00)80464-1 |
0.313 |
|
| 1997 |
Bachmann MF, Mariathasan S, Bouchard D, Speiser DE, Ohashi PS. Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists. European Journal of Immunology. 27: 3414-9. PMID 9464830 DOI: 10.1002/Eji.1830271241 |
0.632 |
|
| 1997 |
Yeh WC, Shahinian A, Speiser D, Kraunus J, Billia F, Wakeham A, De La Pompa JL, Ferrick D, Hum B, Iscove N, Ohashi P, Rothe M, Goeddel DV, Mak TW. Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice Immunity. 7: 715-725. PMID 9390694 DOI: 10.1016/S1074-7613(00)80391-X |
0.387 |
|
| 1997 |
Bachmann MF, Ohteki T, Faienza KM, Zakarian A, Kägi D, Speiser DE, Ohashi PS. Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis. Journal of Immunology (Baltimore, Md. : 1950). 159: 4165-70. PMID 9379009 |
0.374 |
|
| 1997 |
Bachmann MF, McKall-Faienza K, Schmits R, Bouchard D, Beach J, Speiser DE, Mak TW, Ohashi PS. Distinct roles for LFA-1 and CD28 during activation of naive T cells: Adhesion versus costimulation Immunity. 7: 549-557. PMID 9354475 |
0.39 |
|
| 1997 |
Bachmann MF, Oxenius A, Speiser DE, Mariathasan S, Hengartner H, Zinkernagel RM, Ohashi PS. Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation. European Journal of Immunology. 27: 2195-203. PMID 9341759 DOI: 10.1002/Eji.1830270912 |
0.682 |
|
| 1997 |
Waterhouse P, Bachmann MF, Penninger JM, Ohashi PS, Mak TW. Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice European Journal of Immunology. 27: 1887-1892. PMID 9295023 DOI: 10.1002/Eji.1830270811 |
0.376 |
|
| 1997 |
Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes. The Journal of Experimental Medicine. 186: 941-53. PMID 9294148 DOI: 10.1084/Jem.186.6.941 |
0.306 |
|
| 1997 |
Kawai K, Ohashi PS. "Normal" development of Vgamma3 dendritic epidermal T cells in CD45-deficient mice? The Journal of Investigative Dermatology. 109: 250-1. PMID 9242517 DOI: 10.1111/1523-1747.ep12319800 |
0.311 |
|
| 1997 |
Speiser DE, Lee SY, Wong B, Arron J, Santana A, Kong YY, Ohashi PS, Choi Y. A regulatory role for TRAF1 in antigen-induced apoptosis of T cells. The Journal of Experimental Medicine. 185: 1777-83. PMID 9151703 DOI: 10.1084/Jem.185.10.1777 |
0.38 |
|
| 1997 |
Bachmann MF, Kündig TM, Speiser DE, McKall-Faienza K, Kishara K, Mak TW, Ohashi PS. T-cell-independent antiviral B cell responses in CD45-deficient mice Cellular Immunology. 175: 12-15. PMID 9015183 DOI: 10.1006/cimm.1996.1041 |
0.367 |
|
| 1996 |
Ohashi PS. T cell selection and autoimmunity: Flexibility and tuning Current Opinion in Immunology. 8: 808-814. PMID 8994860 DOI: 10.1016/S0952-7915(96)80009-4 |
0.337 |
|
| 1996 |
Speiser DE, Sebzda E, Ohteki T, Bachmann MF, Pfeffer K, Mak TW, Ohashi PS. Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo European Journal of Immunology. 26: 3055-3060. PMID 8977304 |
0.379 |
|
| 1996 |
Bachmann MF, Sebzda E, Kündig TM, Shahinian A, Speiser DE, Mak TW, Ohashi PS. T cell responses are governed by avidity and co-stimulatory thresholds European Journal of Immunology. 26: 2017-2022. PMID 8814240 |
0.396 |
|
| 1996 |
Kündig TM, Bachmann MF, Oehen S, Hoffmann UW, Simard JJ, Kalberer CP, Pircher H, Ohashi PS, Hengartner H, Zinkernagel RM. On the role of antigen in maintaining cytotoxic T-cell memory. Proceedings of the National Academy of Sciences of the United States of America. 93: 9716-23. PMID 8790397 DOI: 10.1073/pnas.93.18.9716 |
0.345 |
|
| 1996 |
Kündig TM, Bachmann MF, Ohashi PS, Pircher H, Hengartner H, Zinkernagel RM. On T cell memory: arguments for antigen dependence. Immunological Reviews. 150: 63-90. PMID 8782702 DOI: 10.1111/J.1600-065X.1996.Tb00696.X |
0.31 |
|
| 1996 |
Kündig TM, Shahinian A, Kawai K, Mittrücker HW, Sebzda E, Bachmann MF, Mak TW, Ohashi PS. Duration of TCR stimulation determines costimulatory requirement of T cells Immunity. 5: 41-52. PMID 8758893 DOI: 10.1016/S1074-7613(00)80308-8 |
0.407 |
|
| 1996 |
Yeung RSM, Penninger JM, Kündig T, Khoo W, Ohashi PS, Kroemer G, Mak TW. Human CD4 and human major histocompatibility complex class II (DQ6) transgenic mice: Supersensitivity to superantigen-induced septic shock European Journal of Immunology. 26: 1074-1082. PMID 8647170 DOI: 10.1002/Eji.1830260518 |
0.3 |
|
| 1996 |
Kägi D, Odermatt B, Ohashi PS, Zinkernagel RM, Hengartner H. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity. The Journal of Experimental Medicine. 183: 2143-52. PMID 8642324 DOI: 10.1084/jem.183.5.2143 |
0.362 |
|
| 1996 |
Kawai K, Shahinian A, Mak TW, Ohashi PS. Skin allograft rejection in CD28-deficient mice Transplantation. 61: 352-355. PMID 8610339 DOI: 10.1097/00007890-199602150-00003 |
0.319 |
|
| 1996 |
Amakawa R, Hakem A, Kundig TM, Matsuyama T, Simard JJ, Timms E, Wakeham A, Mittruecker HW, Griesser H, Takimoto H, Schmits R, Shahinian A, Ohashi P, Penninger JM, Mak TW. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice. Cell. 84: 551-62. PMID 8598042 DOI: 10.1016/S0092-8674(00)81031-4 |
0.34 |
|
| 1996 |
Speiser DE, Sebzda E, Ohteki T, Bachmann MF, Mak TW, Ohashi PS. TNF receptor p55 mediates peripheral cytotoxic T cell deletion Faseb Journal. 10. |
0.403 |
|
| 1996 |
Bachmann MF, Sehzda E, Kuendig TM, Shahinian A, Speiser D, Mak TW, Ohashi PS. T cell responses are governed by avidity and costimulatory thresholds Faseb Journal. 10. |
0.381 |
|
| 1995 |
Kawai K, Ohashi PS. Immunological function of a defined T-cell population tolerized to low-affinity self antigens Nature. 374: 68-69. PMID 7870174 |
0.337 |
|
| 1995 |
Kawai K, Kishihara K, Molina TJ, Wallace VA, Mak TW, Ohashi PS. Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient mice. The Journal of Experimental Medicine. 181: 345-9. PMID 7807014 |
0.346 |
|
| 1995 |
Suzuki H, Kündig TM, Furlonger C, Wakeham A, Timms E, Matsuyama T, Schmits R, Simard JJ, Ohashi PS, Griesser H. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science (New York, N.Y.). 268: 1472-6. PMID 7770771 DOI: 10.1126/Science.7770771 |
0.482 |
|
| 1995 |
Kündig TM, Bachmann MF, DiPaolo C, Simard JJ, Battegay M, Lother H, Gessner A, Kühlcke K, Ohashi PS, Hengartner H. Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science (New York, N.Y.). 268: 1343-7. PMID 7761853 DOI: 10.1126/Science.7761853 |
0.476 |
|
| 1995 |
Ally BA, Hawley TS, McKall-Faienza KJ, Kündig TM, Oehen SU, Pircher H, Hawley RG, Ohashi PS. Prevention of autoimmune disease by retroviral-mediated gene therapy. Journal of Immunology (Baltimore, Md. : 1950). 155: 5404-8. PMID 7594557 |
0.306 |
|
| 1994 |
Aichele P, Kyburz D, Ohashi PS, Odermatt B, Zinkernagel RM, Hengartner H, Pircher H. Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America. 91: 444-8. PMID 8290546 DOI: 10.1073/Pnas.91.2.444 |
0.323 |
|
| 1994 |
Oehen SU, Ohashi PS, Bürki K, Hengartner H, Zinkernagel RM, Aichele P. Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels. Cellular Immunology. 158: 342-52. PMID 7923387 DOI: 10.1006/cimm.1994.1281 |
0.303 |
|
| 1994 |
Rahemtulla A, Kündig TM, Narendran A, Bachmann MF, Julius M, Paige CJ, Ohashi PS, Zinkernagel RM, Mak TW. Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice. European Journal of Immunology. 24: 2213-8. PMID 7916297 DOI: 10.1002/Eji.1830240942 |
0.334 |
|
| 1994 |
Harlan DM, Hengartner H, Huang ML, Kang YH, Abe R, Moreadith RW, Pircher H, Gray GS, Ohashi PS, Freeman GJ. Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proceedings of the National Academy of Sciences of the United States of America. 91: 3137-41. PMID 7512724 DOI: 10.1073/pnas.91.8.3137 |
0.378 |
|
| 1994 |
Ohashi PS. ″Ignorance is bliss″ [T cell tolerance] Immunologist. 2: 87-92. |
0.317 |
|
| 1993 |
Pfeffer K, Matsuyama T, Kündig TM, Wakeham A, Kishihara K, Shahinian A, Wiegmann K, Ohashi PS, Krönke M, Mak TW. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection Cell. 73: 457-467. PMID 8387893 DOI: 10.1016/0092-8674(93)90134-C |
0.312 |
|
| 1993 |
Shahinian A, Pfeffer K, Lee KP, Kündig TM, Kishihara K, Wakeham A, Kawai K, Ohashi PS, Thompson CB, Mak TW. Differential T cell costimulatory requirements in CD28-deficient mice Science. 261: 609-612. PMID 7688139 DOI: 10.1126/Science.7688139 |
0.383 |
|
| 1992 |
Crompton T, Macdonald HR, Ohashi P, Schneider SD, Pircher H. A cortisone sensitive cd3|0w subset of d4+cd8" thymocytes represents an intermediate stage in intrathymic repertoire selection International Immunology. 4: 153-161. PMID 1535784 DOI: 10.1093/Intimm/4.2.153 |
0.329 |
|
| 1992 |
Speiser DE, Pircher H, Ohashi PS, Kyburz D, Hengartner H, Zinkernagel RM. Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny. The Journal of Experimental Medicine. 175: 1277-83. PMID 1533241 DOI: 10.1084/Jem.175.5.1277 |
0.363 |
|
| 1992 |
Zinkernagel RM, Pircher H, Ohashi PS, Hengartner H. T cells causing immunological disease. Springer Seminars in Immunopathology. 14: 105-13. PMID 1475738 DOI: 10.1007/BF00195288 |
0.339 |
|
| 1992 |
Wilson A, Pircher H, Ohashi P, MacDonald HR. Analysis of immature (CD4-CD8-) thymic subsets in T-cell receptor alpha beta transgenic mice. Developmental Immunology. 2: 85-94. PMID 1386545 DOI: 10.1155/1992/45150 |
0.384 |
|
| 1991 |
Zinkernagel RM, Pircher HP, Ohashi P, Oehen S, Odermatt B, Mak T, Arnheiter H, Bürki K, Hengartner H. T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease. Immunological Reviews. 122: 133-71. PMID 1937540 DOI: 10.1111/J.1600-065X.1991.Tb00601.X |
0.496 |
|
| 1991 |
Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, Odermatt B, Malissen B, Zinkernagel RM, Hengartner H. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell. 65: 305-17. PMID 1901764 DOI: 10.1016/0092-8674(91)90164-T |
0.387 |
|
| 1990 |
Pircher H, Ohashi P, Miescher G, Lang R, Zikopoulos A, Bürki K, Mak TW, MacDonald HR, Hengartner H. T cell receptor (TcR) beta chain transgenic mice: studies on allelic exclusion and on the TcR+ gamma/delta population. European Journal of Immunology. 20: 417-24. PMID 1968840 DOI: 10.1002/Eji.1830200227 |
0.373 |
|
| 1989 |
Ferrick DA, Ohashi PS, Wallace V, Schilham M, Mak TW. Thymic ontogeny and selection of αβ and γδ T cells Immunology Today. 10: 403-407. PMID 2619879 DOI: 10.1016/0167-5699(89)90035-2 |
0.308 |
|
| 1987 |
Mak TW, Caccia N, Reis M, Ohashi P, Sangster R, Kimura N, Toyonaga B. Genes Encoding the α, β, and γ Chains of the Human T Cell Antigen Receptor Journal of Infectious Diseases. 155: 418-422. PMID 3543154 DOI: 10.1093/Infdis/155.3.418 |
0.338 |
|
| 1986 |
Mak TW, Caccia N, Kimura N, Spolski R, Iwamoto A, Ohashi P, Reis MD, Toyonaga B. Structures and evolution of the T-cell antigen receptor genes Cold Spring Harbor Symposia On Quantitative Biology. 51: 797-802. PMID 3472762 DOI: 10.1101/Sqb.1986.051.01.092 |
0.389 |
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