Aron M. Geurts, Ph.D. - Publications

2006 University of Minnesota, Twin Cities, Minneapolis, MN 

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 McPherson KC, Taylor L, Johnson AC, Didion SP, Geurts AM, Garrett MR, Williams JM. Early development of podocyte injury independent of hyperglycemia and elevations in arterial pressure in non-diabetic obese Dahl SS leptin receptor mutant rats. American Journal of Physiology. Renal Physiology. ajprenal.00590.2015. PMID 27465994 DOI: 10.1152/ajprenal.00590.2015  0.4
2016 Geurts AM, Ekker SC. Gene Editing: Practical Application in the Lab. Human Gene Therapy. 27: 417-8. PMID 27322167 DOI: 10.1089/hum.2016.29029.amg  0.4
2016 Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW, Geurts AM, Staruschenko A, Imig JD, Sorokin A. p66Shc regulates renal vascular tone in hypertension-induced nephropathy. The Journal of Clinical Investigation. PMID 27270176 DOI: 10.1172/JCI75079  0.4
2016 Mitzelfelt KA, Limphong P, Choi MJ, Kondrat FD, Lai S, Kolander KD, Kwok WM, Dai Q, Grzybowski MN, Zhang H, Taylor GM, Lui Q, Thao MT, Hudson JA, Barresi R, ... ... Geurts AM, et al. Human 343delT HSPB5 Chaperone associated with Early-onset Skeletal Myopathy causes Defects in Protein Solubility. The Journal of Biological Chemistry. PMID 27226619 DOI: 10.1074/jbc.M116.730481  0.4
2016 Kuijk EW, Rasmussen S, Blokzijl F, Huch M, Gehart H, Toonen P, Begthel H, Clevers H, Geurts AM, Cuppen E. Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure. Scientific Reports. 6: 22154. PMID 26915950 DOI: 10.1038/srep22154  0.4
2016 Bennett B, Helbling D, Meng H, Jarzembowski J, Geurts AM, Friederich MW, Van Hove JL, Lawlor MW, Dimmock DP. Potentially diagnostic electron paramagnetic resonance spectra elucidate the underlying mechanism of mitochondrial dysfunction in the deoxyguanosine kinase deficient rat model of a genetic mitochondrial DNA depletion syndrome. Free Radical Biology & Medicine. PMID 26773591 DOI: 10.1016/j.freeradbiomed.2016.01.001  0.4
2016 Priestley JR, Kautenburg KE, Casati MC, Endres BT, Geurts AM, Lombard JH. The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction. American Journal of Physiology. Heart and Circulatory Physiology. 310: H478-87. PMID 26637559 DOI: 10.1152/ajpheart.00586.2015  0.4
2015 Cowley AW, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Hypertension. PMID 26644237 DOI: 10.1161/HYPERTENSIONAHA.115.06280  0.4
2015 Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA. Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. Purinergic Signalling. PMID 26385692 DOI: 10.1007/s11302-015-9470-7  0.4
2015 Endres BT, Staruschenko A, Schulte M, Geurts AM, Palygin O. Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta. Journal of Visualized Experiments : Jove. e52734. PMID 26132549 DOI: 10.3791/52734  0.4
2015 Holditch SJ, Schreiber CA, Nini R, Tonne JM, Peng KW, Geurts A, Jacob HJ, Burnett JC, Cataliotti A, Ikeda Y. B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension. Hypertension. 66: 199-210. PMID 26063669 DOI: 10.1161/HYPERTENSIONAHA.115.05610  0.4
2015 Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A. 2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. Journal of Cardiovascular Translational Research. 8: 269-77. PMID 25920443 DOI: 10.1007/s12265-015-9626-4  0.4
2015 Qin W, Dion SL, Kutny PM, Zhang Y, Cheng AW, Jillette NL, Malhotra A, Geurts AM, Chen YG, Wang H. Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease. Genetics. 200: 423-30. PMID 25819794 DOI: 10.1534/genetics.115.176594  0.4
2015 Rudemiller NP, Lund H, Priestley JR, Endres BT, Prokop JW, Jacob HJ, Geurts AM, Cohen EP, Mattson DL. Mutation of SH2B3 (LNK), a genome-wide association study candidate for hypertension, attenuates Dahl salt-sensitive hypertension via inflammatory modulation. Hypertension. 65: 1111-7. PMID 25776069 DOI: 10.1161/HYPERTENSIONAHA.114.04736  0.4
2015 Flister MJ, Hoffman MJ, Lemke A, Prisco SZ, Rudemiller N, O'Meara CC, Tsaih SW, Moreno C, Geurts AM, Lazar J, Adhikari N, Hall JL, Jacob HJ. SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis. Circulation. Cardiovascular Genetics. 8: 294-304. PMID 25628389 DOI: 10.1161/CIRCGENETICS.114.000527  0.4
2015 Fan F, Geurts AM, Murphy SR, Pabbidi MR, Jacob HJ, Roman RJ. Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308: R379-90. PMID 25540098 DOI: 10.1152/ajpregu.00256.2014  0.4
2015 Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW. Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. Hypertension. 65: 447-55. PMID 25452472 DOI: 10.1161/HYPERTENSIONAHA.114.04179  0.4
2014 Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ. Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice. Bmc Genetics. 15: 135. PMID 25476608 DOI: 10.1186/s12863-014-0135-2  0.4
2014 Fan F, Geurts AM, Pabbidi MR, Smith SV, Harder DR, Jacob H, Roman RJ. Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. Plos One. 9: e112878. PMID 25397684 DOI: 10.1371/journal.pone.0112878  0.4
2014 Flister MJ, Endres BT, Rudemiller N, Sarkis AB, Santarriaga S, Roy I, Lemke A, Geurts AM, Moreno C, Ran S, Tsaih SW, De Pons J, Carlson DF, Tan W, Fahrenkrug SC, et al. CXM: a new tool for mapping breast cancer risk in the tumor microenvironment. Cancer Research. 74: 6419-29. PMID 25172839 DOI: 10.1158/0008-5472.CAN-13-3212  0.4
2014 Endres BT, Priestley JR, Palygin O, Flister MJ, Hoffman MJ, Weinberg BD, Grzybowski M, Lombard JH, Staruschenko A, Moreno C, Jacob HJ, Geurts AM. Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Proceedings of the National Academy of Sciences of the United States of America. 111: 12817-22. PMID 25136115 DOI: 10.1073/pnas.1410745111  0.4
2014 Jin C, Sun J, Stilphen CA, Smith SM, Ocasio H, Bermingham B, Darji S, Guha A, Patel R, Geurts AM, Jacob HJ, Lambert NA, O'Connor PM. HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats. Hypertension. 64: 541-50. PMID 24935944 DOI: 10.1161/HYPERTENSIONAHA.114.03549  0.4
2014 Rudemiller N, Lund H, Jacob HJ, Geurts AM, Mattson DL. CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney. Hypertension. 63: 559-64. PMID 24343121 DOI: 10.1161/HYPERTENSIONAHA.113.02191  0.4
2014 Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH. Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. American Journal of Physiology. Heart and Circulatory Physiology. 306: H339-47. PMID 24322611 DOI: 10.1152/ajpheart.00619.2012  0.4
2014 Chen YG, Forsberg MH, Khaja S, Ciecko AE, Hessner MJ, Geurts AM. Gene targeting in NOD mouse embryos using zinc-finger nucleases. Diabetes. 63: 68-74. PMID 23974926 DOI: 10.2337/db13-0192  0.4
2014 Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA. Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. Neuropharmacology. 76: 250-8. PMID 23791960 DOI: 10.1016/j.neuropharm.2013.05.047  0.4
2013 Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C. Identifying multiple causative genes at a single GWAS locus. Genome Research. 23: 1996-2002. PMID 24006081 DOI: 10.1101/gr.160283.113  0.4
2013 Mattson DL, Lund H, Guo C, Rudemiller N, Geurts AM, Jacob H. Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R407-14. PMID 23364523 DOI: 10.1152/ajpregu.00304.2012  0.4
2013 Chen CC, Geurts AM, Jacob HJ, Fan F, Roman RJ. Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury. Physiological Genomics. 45: 110-8. PMID 23249995 DOI: 10.1152/physiolgenomics.00119.2012  0.4
2013 Katter K, Geurts AM, Hoffmann O, Mátés L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, et al. Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 930-41. PMID 23195032 DOI: 10.1096/fj.12-205526  0.4
2012 Feng D, Yang C, Geurts AM, Kurth T, Liang M, Lazar J, Mattson DL, O'Connor PM, Cowley AW. Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell Metabolism. 15: 201-8. PMID 22326221 DOI: 10.1016/j.cmet.2012.01.003  0.4
2011 Wilber A, Ulloa Montoya F, Hammer L, Moriarity BS, Geurts AM, Largaespada DA, Verfaillie CM, McIvor RS, Lakshmipathy U. Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells. Stem Cells International. 2011: 717069. PMID 21977042 DOI: 10.4061/2011/717069  0.4
2011 Dwinell MR, Lazar J, Geurts AM. The emerging role for rat models in gene discovery. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 466-75. PMID 21732192 DOI: 10.1007/s00335-011-9346-2  0.4
2011 Xu D, Guo H, Xu X, Lu Z, Fassett J, Hu X, Xu Y, Tang Q, Hu D, Somani A, Geurts AM, Ostertag E, Bache RJ, Weir EK, Chen Y. Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase. Hypertension. 58: 303-9. PMID 21730301 DOI: 10.1161/HYPERTENSIONAHA.110.166819  0.4
2011 Moreno C, Hoffman M, Stodola TJ, Didier DN, Lazar J, Geurts AM, North PE, Jacob HJ, Greene AS. Creation and characterization of a renin knockout rat. Hypertension. 57: 614-9. PMID 21242461 DOI: 10.1161/HYPERTENSIONAHA.110.163840  0.4
2011 Taylor SB, Taylor AR, Markham JA, Geurts AM, Kanaskie BZ, Koenig JI. Disruption of the neuregulin 1 gene in the rat alters HPA axis activity and behavioral responses to environmental stimuli. Physiology & Behavior. 104: 205-14. PMID 21092742 DOI: 10.1016/j.physbeh.2010.11.015  0.4
2011 Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC. Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic Research. 20: 29-45. PMID 20352328 DOI: 10.1007/s11248-010-9386-5  0.4
2010 Jacob HJ, Lazar J, Dwinell MR, Moreno C, Geurts AM. Gene targeting in the rat: advances and opportunities. Trends in Genetics : Tig. 26: 510-8. PMID 20869786 DOI: 10.1016/j.tig.2010.08.006  0.4
2010 Geurts AM, Moreno C. Zinc-finger nucleases: new strategies to target the rat genome. Clinical Science (London, England : 1979). 119: 303-11. PMID 20615201 DOI: 10.1042/CS20100201  0.4
2010 Geurts AM, Cost GJ, Rémy S, Cui X, Tesson L, Usal C, Ménoret S, Jacob HJ, Anegon I, Buelow R. Generation of gene-specific mutated rats using zinc-finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 597: 211-25. PMID 20013236 DOI: 10.1007/978-1-60327-389-3_15  0.4
2009 Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, et al. Knockout rats via embryo microinjection of zinc-finger nucleases. Science (New York, N.Y.). 325: 433. PMID 19628861 DOI: 10.1126/science.1172447  0.4
2008 Aitman TJ, Critser JK, Cuppen E, Dominiczak A, Fernandez-Suarez XM, Flint J, Gauguier D, Geurts AM, Gould M, Harris PC, Holmdahl R, Hubner N, Izsvák Z, Jacob HJ, Kuramoto T, et al. Progress and prospects in rat genetics: a community view. Nature Genetics. 40: 516-22. PMID 18443588 DOI: 10.1038/ng.147  0.4
2007 Hackett CS, Geurts AM, Hackett PB. Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome Biology. 8: S12. PMID 18047689 DOI: 10.1186/gb-2007-8-s1-s12  0.4
2007 Lu B, Geurts AM, Poirier C, Petit DC, Harrison W, Overbeek PA, Bishop CE. Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 338-46. PMID 17557177 DOI: 10.1007/s00335-007-9025-5  0.4
2007 Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW. Efficient transgenic rat production by a lentiviral vector. American Journal of Physiology. Heart and Circulatory Physiology. 293: H881-94. PMID 17322424 DOI: 10.1152/ajpheart.00060.2007  0.4
2006 Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/journal.pgen.0020169  0.4
2006 Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. Plos Genetics. 2: e156. PMID 17009875 DOI: 10.1371/journal.pgen.0020156  0.4
2006 Geurts AM, Wilber A, Carlson CM, Lobitz PD, Clark KJ, Hackett PB, McIvor RS, Largaespada DA. Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. Bmc Biotechnology. 6: 30. PMID 16800892 DOI: 10.1186/1472-6750-6-30  0.4
2006 Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB. Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic Acids Research. 34: 2803-11. PMID 16717285 DOI: 10.1093/nar/gkl301  0.4
2005 Liu G, Geurts AM, Yae K, Srinivasan AR, Fahrenkrug SC, Largaespada DA, Takeda J, Horie K, Olson WK, Hackett PB. Target-site preferences of Sleeping Beauty transposons. Journal of Molecular Biology. 346: 161-73. PMID 15663935 DOI: 10.1016/j.jmb.2004.09.086  0.4
2004 Clark KJ, Geurts AM, Bell JB, Hackett PB. Transposon vectors for gene-trap insertional mutagenesis in vertebrates. Genesis (New York, N.Y. : 2000). 39: 225-33. PMID 15286994 DOI: 10.1002/gene.20049  0.4
2003 Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 108-17. PMID 12842434 DOI: 10.1016/S1525-0016(03)00099-6  0.4
2002 Cui Z, Geurts AM, Liu G, Kaufman CD, Hackett PB. Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. Journal of Molecular Biology. 318: 1221-35. PMID 12083513 DOI: 10.1016/S0022-2836(02)00237-1  0.4
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