Santhakumar Manicassamy, Ph.D. - Publications

Affiliations: 
2006 University of Illinois at Chicago, Health Sciences Center 
Area:
Immunology, Microbiology Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Manoharan I, Prasad PD, Thangaraju M, Manicassamy S. Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages. Frontiers in Immunology. 12: 691134. PMID 34394085 DOI: 10.3389/fimmu.2021.691134  1
2021 Manoharan I, Swafford D, Shanmugam A, Patel N, Prasad PD, Thangaraju M, Manicassamy S. Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 34348977 DOI: 10.4049/jimmunol.2100010  1
2021 Bridges AE, Ramachandran S, Tamizhmani K, Parwal U, Lester A, Rajpurohit P, Morera DS, Hasanali SL, Arjunan P, Jedeja RN, Patel N, Marin PM, Korkaya H, Singh N, Manicassamy S, et al. RAD51AP1 loss attenuates colorectal cancer stem cell renewal and sensitizes to chemotherapy. Molecular Cancer Research : McR. PMID 34099522 DOI: 10.1158/1541-7786.MCR-20-0780  1
2021 Manicassamy S, Prasad PD, Swafford D. Mouse Models of Colitis-Associated Colon Cancer. Methods in Molecular Biology (Clifton, N.J.). 2224: 133-146. PMID 33606212 DOI: 10.1007/978-1-0716-1008-4_10  1
2020 Swafford D, Shanmugam A, Ranganathan P, Manoharan I, Hussein MS, Patel N, Sifuentes H, Koni PA, Prasad PD, Thangaraju M, Manicassamy S. The Wnt-β-Catenin-IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota. Journal of Immunology (Baltimore, Md. : 1950). PMID 32917787 DOI: 10.4049/Jimmunol.1901376  1
2020 Vogel OA, Han J, Liang CY, Manicassamy S, Perez JT, Manicassamy B. The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection. Plos Pathogens. 16: e1008842. PMID 32898178 DOI: 10.1371/Journal.Ppat.1008842  1
2020 Bridges AE, Ramachandran S, Pathania R, Parwal U, Lester A, Rajpurohit P, Morera DS, Patel N, Singh N, Korkaya H, Manicassamy S, Prasad PD, Lokeshwar VB, Lokeshwar BL, Ganapathy V, et al. RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal. Cancer Research. PMID 32665355 DOI: 10.1158/0008-5472.Can-19-3713  1
2020 Suryawanshi A, Hussein MS, Prasad PD, Manicassamy S. Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity. Frontiers in Immunology. 11: 122. PMID 32132993 DOI: 10.3389/Fimmu.2020.00122  1
2020 Kandasamy M, Furlong K, Perez JT, Manicassamy S, Manicassamy B. Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue Resident Memory T cell During H5N1 infection. Journal of Virology. PMID 32075925 DOI: 10.1128/Jvi.00057-20  1
2020 Artham S, Verma A, Alwhaibi A, Adil MS, Manicassamy S, Munn DH, Somanath PR. Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T-cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32073894 DOI: 10.1152/Ajplung.00251.2019  1
2018 Swafford D, Shanmugam A, Ranganathan P, Hussein MS, Koni PA, Prasad PD, Thangaraju M, Manicassamy S. Canonical Wnt Signaling in CD11cAPCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon. Journal of Immunology (Baltimore, Md. : 1950). PMID 29602775 DOI: 10.4049/Jimmunol.1701086  1
2018 Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein MS, Koni PA, Prasad PD, Kurago ZB, Thangaraju M, Ganapathy V, Manicassamy S. GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 29386257 DOI: 10.4049/Jimmunol.1700604  1
2016 Suryawanshi A, Tadagavadi RK, Swafford D, Manicassamy S. Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer. Frontiers in Immunology. 7: 460. PMID 27833613 DOI: 10.3389/Fimmu.2016.00460  1
2016 Kandasamy M, Suryawanshi A, Tundup S, Perez JT, Schmolke M, Manicassamy S, Manicassamy B. RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection. Plos Pathogens. 12: e1005754. PMID 27438481 DOI: 10.1371/Journal.Ppat.1005754  1
2016 Pathania R, Ramachandran S, Mariappan G, Thakur P, Shi H, Choi JH, Manicassamy S, Kolhe R, Prasad PD, Sharma S, Lokeshwar BL, Ganapathy V, Thangaraju M. Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth. Cancer Research. PMID 27197203 DOI: 10.1158/0008-5472.Can-15-2249  1
2016 Manoharan I, Suryawanshi A, Hong Y, Ranganathan P, Shanmugam A, Ahmad S, Swafford D, Manicassamy B, Ramesh G, Koni PA, Thangaraju M, Manicassamy S. Homeostatic PPARα Signaling Limits Inflammatory Responses to Commensal Microbiota in the Intestine. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183583 DOI: 10.4049/Jimmunol.1501489  1
2016 Hong Y, Manoharan I, Suryawanshi A, Shanmugam A, Swafford D, Ahmad S, Chinnadurai R, Manicassamy B, He Y, Mellor AL, Thangaraju M, Munn DH, Manicassamy S. Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity. Oncoimmunology. 5: e1115941. PMID 27141399 DOI: 10.1080/2162402X.2015.1115941  1
2015 Suryawanshi A, Manicassamy S. Tumors induce immune tolerance through activation of β-catenin/TCF4 signaling in dendritic cells: A novel therapeutic target for cancer immunotherapy. Oncoimmunology. 4: e1052932. PMID 26587326 DOI: 10.1080/2162402X.2015.1052932  1
2015 Swafford D, Manicassamy S. Wnt signaling in dendritic cells: its role in regulation of immunity and tolerance. Discovery Medicine. 19: 303-10. PMID 25977193  1
2015 Pathania R, Ramachandran S, Elangovan S, Padia R, Yang P, Cinghu S, Veeranan-Karmegam R, Arjunan P, Gnana-Prakasam JP, Sadanand F, Pei L, Chang CS, Choi JH, Shi H, Manicassamy S, et al. DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis. Nature Communications. 6: 6910. PMID 25908435 DOI: 10.1038/Ncomms7910  1
2015 Suryawanshi A, Manoharan I, Hong Y, Swafford D, Majumdar T, Taketo MM, Manicassamy B, Koni PA, Thangaraju M, Sun Z, Mellor AL, Munn DH, Manicassamy S. Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 3295-304. PMID 25710911 DOI: 10.4049/Jimmunol.1402691  1
2015 Hong Y, Manoharan I, Suryawanshi A, Majumdar T, Angus-Hill ML, Koni PA, Manicassamy B, Mellor AL, Munn DH, Manicassamy S. β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells. Cancer Research. 75: 656-65. PMID 25568183 DOI: 10.1158/0008-5472.Can-14-2377  1
2015 Hong Y, Manoharan I, Suryawanshi A, Manicassamy S. Abstract 5036: Tumor-induced activation of the Wnt/β-catenin/TCF4 pathway in dendritic cells promotes immune tolerance Cancer Research. 75: 5036-5036. DOI: 10.1158/1538-7445.Am2015-5036  1
2014 Manoharan I, Hong Y, Suryawanshi A, Angus-Hill ML, Sun Z, Mellor AL, Munn DH, Manicassamy S. TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation. Journal of Immunology (Baltimore, Md. : 1950). 193: 4203-13. PMID 25210120 DOI: 10.4049/Jimmunol.1400614  1
2014 Manicassamy S, Manoharan I. Mouse models of acute and chronic colitis. Methods in Molecular Biology (Clifton, N.J.). 1194: 437-48. PMID 25064119 DOI: 10.1007/978-1-4939-1215-5_25  1
2014 Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V. Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. Immunity. 40: 128-39. PMID 24412617 DOI: 10.1016/J.Immuni.2013.12.007  1
2013 Ranganathan P, Jayakumar C, Manicassamy S, Ramesh G. CXCR2 knockout mice are protected against DSS-colitis-induced acute kidney injury and inflammation. American Journal of Physiology. Renal Physiology. 305: F1422-7. PMID 23986515 DOI: 10.1152/Ajprenal.00319.2013  1
2011 Denning TL, Norris BA, Medina-Contreras O, Manicassamy S, Geem D, Madan R, Karp CL, Pulendran B. Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization. Journal of Immunology (Baltimore, Md. : 1950). 187: 733-47. PMID 21666057 DOI: 10.4049/Jimmunol.1002701  1
2011 Manicassamy S, Pulendran B. Dendritic cell control of tolerogenic responses. Immunological Reviews. 241: 206-27. PMID 21488899 DOI: 10.1111/J.1600-065X.2011.01015.X  1
2011 Ganguly S, Manicassamy S, Blackwell J, Pulendran B, Amara RR. Adenovirus type 5 induces vitamin A-metabolizing enzymes in dendritic cells and enhances priming of gut-homing CD8 T cells Mucosal Immunology. 4: 528-538. PMID 21289616 DOI: 10.1038/Mi.2011.1  1
2011 Manicassamy S, Pulendran B. Response to comment on "activation of β-catenin in dendritic cells regulates immunity versus tolerance in the intestine", Science. 333. DOI: 10.1126/Science.1198771  1
2010 Manicassamy S, Reizis B, Ravindran R, Nakaya H, Salazar-Gonzalez RM, Wang YC, Pulendran B. Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine. Science (New York, N.Y.). 329: 849-53. PMID 20705860 DOI: 10.1126/Science.1188510  1
2010 Pulendran B, Tang H, Manicassamy S. Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nature Immunology. 11: 647-55. PMID 20644570 DOI: 10.1038/Ni.1894  1
2010 Manicassamy B, Manicassamy S, Belicha-Villanueva A, Pisanelli G, Pulendran B, García-Sastre A. Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 11531-6. PMID 20534532 DOI: 10.1073/Pnas.0914994107  1
2009 Jiang H, Wang J, Manicassamy B, Manicassamy S, Caffrey M, Rong L. The Role of the Charged Residues of the GP2 Helical Regions in Ebola Entry(). Virologica Sinica. 24: 121-135. PMID 23227032 DOI: 10.1007/S12250-009-3015-6  1
2009 Manicassamy S. Sotrastaurin, a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis. Current Opinion in Investigational Drugs (London, England : 2000). 10: 1225-35. PMID 19876790  1
2009 Manicassamy S, Pulendran B. Modulation of adaptive immunity with Toll-like receptors. Seminars in Immunology. 21: 185-93. PMID 19502082 DOI: 10.1016/J.Smim.2009.05.005  1
2009 Manicassamy S, Ravindran R, Deng J, Oluoch H, Denning TL, Kasturi SP, Rosenthal KM, Evavold BD, Pulendran B. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nature Medicine. 15: 401-9. PMID 19252500 DOI: 10.1038/Nm.1925  1
2009 Manicassamy S, Pulendran B. Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages. Seminars in Immunology. 21: 22-7. PMID 18778953 DOI: 10.1016/J.Smim.2008.07.007  1
2008 Gupta S, Manicassamy S, Vasu C, Kumar A, Shang W, Sun Z. Differential requirement of PKC-theta in the development and function of natural regulatory T cells. Molecular Immunology. 46: 213-24. PMID 18842300 DOI: 10.1016/J.Molimm.2008.08.275  1
2008 Cao W, Manicassamy S, Tang H, Kasturi SP, Pirani A, Murthy N, Pulendran B. Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nature Immunology. 9: 1157-64. PMID 18758466 DOI: 10.1038/Ni.1645  1
2008 Manicassamy S, Yin D, Zhang Z, Molinero LL, Alegre ML, Sun Z. A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection. Journal of Immunology (Baltimore, Md. : 1950). 181: 513-20. PMID 18566417 DOI: 10.4049/Jimmunol.181.1.513  1
2008 Huang Z, Wang R, Xie H, Shang W, Manicassamy S, Sun Z. Stabilized beta-catenin potentiates Fas-mediated T cell apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 180: 6586-92. PMID 18453577 DOI: 10.4049/Jimmunol.180.10.6586  1
2008 Xiang Z, Ma LL, Manicassamy S, Ganesh BB, Williams P, Chari R, Chong A, Yin DP. CD4+ T cells are sufficient to elicit allograft rejection and major histocompatibility complex class I molecule is required to induce recurrent autoimmune diabetes after pancreas transplantation in mice. Transplantation. 85: 1205-11. PMID 18431243 DOI: 10.1097/Tp.0B013E31816B70Bf  1
2008 Manicassamy S, Gupta S, Huang Z, Molkentin JD, Shang W, Sun Z. Requirement of calcineurin a beta for the survival of naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 106-12. PMID 18097009 DOI: 10.4049/Jimmunol.180.1.106  1
2007 Manicassamy S, Sun Z. The critical role of protein kinase C-theta in Fas/Fas ligand-mediated apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 178: 312-9. PMID 17182568 DOI: 10.4049/Jimmunol.178.1.312  1
2006 Manicassamy S, Gupta S, Sun Z. Selective function of PKC-theta in T cells. Cellular & Molecular Immunology. 3: 263-70. PMID 16978534  1
2006 Manicassamy S, Gupta S, Huang Z, Sun Z. Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL. Journal of Immunology (Baltimore, Md. : 1950). 176: 6709-16. PMID 16709830 DOI: 10.4049/Jimmunol.176.11.6709  1
2006 Gudi R, Barkinge J, Hawkins S, Chu F, Manicassamy S, Sun Z, Duke-Cohan JS, Prasad KV. Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD). Oncogene. 25: 3458-62. PMID 16491128 DOI: 10.1038/Sj.Onc.1209381  1
2006 Manicassamy S, Sadim M, Ye RD, Sun Z. Differential roles of PKC-theta in the regulation of intracellular calcium concentration in primary T cells. Journal of Molecular Biology. 355: 347-59. PMID 16309697 DOI: 10.1016/J.Jmb.2005.10.043  1
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