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Ethan S. Lippmann, Ph.D. - Publications

Affiliations: 
2012 University of Wisconsin, Madison, Madison, WI 
Area:
Chemical Engineering, Biomedical Engineering, Cell Biology
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sorets A, Schwensen K, Francini N, Kjar A, Abdulrahman A, Shostak A, Katdare K, Schoch K, Cowell R, Park J, Ligocki A, Ford W, Ventura-Antunes L, Hoogenboezem E, Prusky A, ... ... Lippmann E, et al. Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system. Biorxiv : the Preprint Server For Biology. PMID 38915549 DOI: 10.1101/2024.06.09.598079  0.354
2024 Katdare KA, Kjar A, O'Brown NM, Neal EH, Sorets AG, Shostak A, Romero-Fernandez W, Kwiatkowski AJ, Mlouk K, Kim H, Cowell RP, Schwensen KR, Horner KB, Wilson JT, Schrag MS, ... ... Lippmann ES, et al. IQGAP2 regulates blood-brain barrier immune dynamics. Biorxiv : the Preprint Server For Biology. PMID 38645082 DOI: 10.1101/2023.02.07.527394  0.379
2022 Kim H, Leng K, Park J, Sorets AG, Kim S, Shostak A, Embalabala RJ, Mlouk K, Katdare KA, Rose IVL, Sturgeon SM, Neal EH, Ao Y, Wang S, Sofroniew MV, ... ... Lippmann ES, et al. Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Nature Communications. 13: 6581. PMID 36323693 DOI: 10.1038/s41467-022-34412-4  0.73
2022 Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, ... ... Lippmann ES, et al. CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states. Nature Neuroscience. PMID 36303069 DOI: 10.1038/s41593-022-01180-9  0.377
2022 Shi Y, Kim H, Hamann CA, Rhea EM, Brunger JM, Lippmann ES. Nuclear receptor ligand screening in an iPSC-derived in vitro blood-brain barrier model identifies new contributors to leptin transport. Fluids and Barriers of the Cns. 19: 77. PMID 36131285 DOI: 10.1186/s12987-022-00375-3  0.394
2022 Rosch JC, Hoogenboezem EN, Sorets AG, Duvall CL, Lippmann ES. Albumin-Binding Aptamer Chimeras for Improved siRNA Bioavailability. Cellular and Molecular Bioengineering. 15: 161-173. PMID 35401842 DOI: 10.1007/s12195-022-00718-y  0.68
2021 Bosworth AM, Kim H, O'Grady KP, Richter I, Lee L, O'Grady BJ, Lippmann ES. Influence of Substrate Stiffness on Barrier Function in an iPSC-Derived Blood-Brain Barrier Model. Cellular and Molecular Bioengineering. 15: 31-42. PMID 35096185 DOI: 10.1007/s12195-021-00706-8  0.402
2021 Neal EH, Katdare KA, Shi Y, Marinelli NA, Hagerla KA, Lippmann ES. Influence of basal media composition on barrier fidelity within human pluripotent stem cell-derived blood-brain barrier models. Journal of Neurochemistry. PMID 34716922 DOI: 10.1111/jnc.15532  0.491
2020 O'Grady BJ, Balotin KM, Bosworth AM, McClatchey PM, Weinstein RM, Gupta M, Poole KS, Bellan LM, Lippmann ES. Development of an N-Cadherin Biofunctionalized Hydrogel to Support the Formation of Synaptically Connected Neural Networks. Acs Biomaterials Science & Engineering. 6: 5811-5822. PMID 33320550 DOI: 10.1021/Acsbiomaterials.0C00885  0.377
2020 Rosch JC, Neal EH, Balikov DA, Rahim M, Lippmann ES. CRISPR-Mediated Isogenic Cell-SELEX Approach for Generating Highly Specific Aptamers Against Native Membrane Proteins. Cellular and Molecular Bioengineering. 13: 559-574. PMID 33184583 DOI: 10.1007/S12195-020-00651-Y  0.305
2020 Lippmann ES, Azarin SM, Palecek SP, Shusta EV. Commentary on human pluripotent stem cell-based blood-brain barrier models. Fluids and Barriers of the Cns. 17: 64. PMID 33076946 DOI: 10.1186/s12987-020-00222-3  0.679
2020 Sorets AG, Rosch JC, Duvall CL, Lippmann ES. Caveolae-Mediated Transport at the Injured Blood-Brain Barrier as an Underexplored Pathway for Central Nervous System Drug Delivery. Current Opinion in Chemical Engineering. 30: 86-95. PMID 32953427 DOI: 10.1016/J.Coche.2020.08.009  0.719
2020 Brown JA, Faley SL, Shi Y, Hillgren KM, Sawada GA, Baker TK, Wikswo JP, Lippmann ES. Advances in blood-brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure. Fluids and Barriers of the Cns. 17: 38. PMID 32493346 DOI: 10.1186/S12987-020-00200-9  0.487
2020 Challa AP, Beam AL, Shen M, Peryea T, Lavieri RR, Lippmann ES, Aronoff DM. Machine learning on drug-specific data to predict small molecule teratogenicity. Reproductive Toxicology (Elmsford, N.Y.). PMID 32428651 DOI: 10.1016/J.Reprotox.2020.05.004  0.309
2020 Robertson GL, Romero-Morales AI, Lippmann ES, Gama V. Uncovering cell biology in the third dimension. Molecular Biology of the Cell. 31: 319-323. PMID 32105584 DOI: 10.1091/Mbc.E19-04-0211  0.509
2019 Romero-Morales AI, O'Grady BJ, Balotin KM, Bellan LM, Lippmann ES, Gama V. Spin∞: an updated miniaturized spinning bioreactor design for the generation of human cerebral organoids from pluripotent stem cells. Hardwarex. 6. PMID 32864515 DOI: 10.1016/J.Ohx.2019.E00084  0.422
2019 O'Grady BJ, Balikov DA, Lippmann ES, Bellan LM. Spatiotemporal Control of Morphogen Delivery to Pattern Stem Cell Differentiation in Three-Dimensional Hydrogels. Current Protocols in Stem Cell Biology. 51: e97. PMID 31756050 DOI: 10.1002/Cpsc.97  0.349
2019 Balikov DA, Neal EH, Lippmann ES. Organotypic Neurovascular Models: Past Results and Future Directions. Trends in Molecular Medicine. PMID 31699496 DOI: 10.1016/J.Molmed.2019.09.010  0.407
2019 Chasman D, Iyer N, Fotuhi Siahpirani A, Estevez Silva M, Lippmann E, McIntosh B, Probasco MD, Jiang P, Stewart R, Thomson JA, Ashton RS, Roy S. Inferring Regulatory Programs Governing Region Specificity of Neuroepithelial Stem Cells during Early Hindbrain and Spinal Cord Development. Cell Systems. PMID 31302154 DOI: 10.1016/J.Cels.2019.05.012  0.336
2019 Neal EH, Marinelli NA, Shi Y, McClatchey PM, Balotin KM, Gullett DR, Hagerla KA, Bowman AB, Ess KC, Wikswo JP, Lippmann ES. A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs. Stem Cell Reports. 12: 1380-1388. PMID 31189096 DOI: 10.1016/J.Stemcr.2019.05.008  0.569
2019 Afshar Bakooshli M, Lippmann ES, Mulcahy B, Iyer N, Nguyen CT, Tung K, Stewart BA, van den Dorpel H, Fuehrmann T, Shoichet M, Bigot A, Pegoraro E, Ahn H, Ginsberg H, Zhen M, et al. A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction. Elife. 8. PMID 31084710 DOI: 10.7554/Elife.44530  0.306
2019 O'Grady B, Balikov DA, Wang JX, Neal EK, Ou YC, Bardhan R, Lippmann ES, Bellan LM. Spatiotemporal control and modeling of morphogen delivery to induce gradient patterning of stem cell differentiation using fluidic channels. Biomaterials Science. PMID 30778445 DOI: 10.1039/C8Bm01199K  0.379
2019 Faley SL, Neal EH, Wang JX, Bosworth AM, Weber CM, Balotin KM, Lippmann ES, Bellan LM. iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds. Stem Cell Reports. PMID 30773484 DOI: 10.1016/J.Stemcr.2019.01.009  0.55
2018 Chiou B, Neal EH, Bowman AB, Lippmann ES, Simpson IA, Connor JR. Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18783372. PMID 29911470 DOI: 10.1177/0271678X18783372  0.439
2018 Chiou B, Neal EH, Bowman AB, Lippmann ES, Simpson IA, Connor JR. Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier. Plos One. 13: e0198775. PMID 29889872 DOI: 10.1371/Journal.Pone.0198775  0.379
2017 Bosworth AM, Faley SL, Bellan LM, Lippmann ES. Modeling Neurovascular Disorders and Therapeutic Outcomes with Human-Induced Pluripotent Stem Cells. Frontiers in Bioengineering and Biotechnology. 5: 87. PMID 29441348 DOI: 10.3389/Fbioe.2017.00087  0.536
2017 Stebbins MJ, Lippmann ES, Faubion MG, Daneman R, Palecek SP, Shusta EV. Activation of RARα, RARγ, or RXRα Increases Barrier Tightness in Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells. Biotechnology Journal. PMID 28960887 DOI: 10.1002/Biot.201700093  0.706
2017 Hollmann EK, Bailey AK, Potharazu AV, Neely MD, Bowman AB, Lippmann ES. Accelerated differentiation of human induced pluripotent stem cells to blood-brain barrier endothelial cells. Fluids and Barriers of the Cns. 14: 9. PMID 28407791 DOI: 10.1186/S12987-017-0059-0  0.558
2016 Rosch JC, Hollmann EK, Lippmann ES. In vitro selection technologies to enhance biomaterial functionality. Experimental Biology and Medicine (Maywood, N.J.). 241: 962-71. PMID 27188514 DOI: 10.1177/1535370216647182  0.305
2015 Lippmann ES, Williams CE, Ruhl DA, Estevez-Silva MC, Chapman ER, Coon JJ, Ashton RS. Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm. Stem Cell Reports. 4: 632-44. PMID 25843047 DOI: 10.1016/J.Stemcr.2015.02.018  0.345
2014 Lippmann ES, Al-Ahmad A, Azarin SM, Palecek SP, Shusta EV. A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources. Scientific Reports. 4: 4160. PMID 24561821 DOI: 10.1038/Srep04160  0.784
2014 Lippmann ES, Estevez-Silva MC, Ashton RS. Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors. Stem Cells (Dayton, Ohio). 32: 1032-42. PMID 24357014 DOI: 10.1002/Stem.1622  0.418
2013 Lippmann ES, Al-Ahmad A, Palecek SP, Shusta EV. Modeling the blood-brain barrier using stem cell sources. Fluids and Barriers of the Cns. 10: 2. PMID 23305164 DOI: 10.1186/2045-8118-10-2  0.788
2012 Lippmann ES, Azarin SM, Kay JE, Nessler RA, Wilson HK, Al-Ahmad A, Palecek SP, Shusta EV. Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. Nature Biotechnology. 30: 783-91. PMID 22729031 DOI: 10.1038/Nbt.2247  0.784
2011 Lippmann ES, Weidenfeller C, Svendsen CN, Shusta EV. Blood-brain barrier modeling with co-cultured neural progenitor cell-derived astrocytes and neurons. Journal of Neurochemistry. 119: 507-20. PMID 21854389 DOI: 10.1111/J.1471-4159.2011.07434.X  0.678
2010 Agarwal N, Lippmann ES, Shusta EV. Identification and expression profiling of blood-brain barrier membrane proteins. Journal of Neurochemistry. 112: 625-35. PMID 19895664 DOI: 10.1111/J.1471-4159.2009.06481.X  0.62
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