Christoph D. Rau, Ph.D. - Publications

Affiliations: 
2013 Microbiology, Immunology, & Molecular Genetics 0440 University of California, Los Angeles, Los Angeles, CA 
Area:
Genetics, Bioinformatics Biology, Systematic Biology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Baranowski BJ, Allen MD, Nyarko JN, Rector RS, Padilla J, Mousseau DD, Rau CD, Wang Y, Laughlin MH, Emter CA, MacPherson RE, Olver TD. Cerebrovascular insufficiency and amyloidogenic signaling in Ossabaw swine with cardiometabolic heart failure. Jci Insight. 6. PMID 34027891 DOI: 10.1172/jci.insight.143141  0.4
2021 Kelly SC, Rau CD, Ouyang A, Thorne PK, Olver TD, Edwards JC, Domeier TL, Padilla J, Grisanti LA, Fleenor BS, Wang Y, Rector RS, Emter CA. The Right Ventricular Transcriptome Signature in Ossabaw Swine with Cardio-Metabolic Heart Failure: Implications for the Coronary Vasculature. Physiological Genomics. PMID 33491589 DOI: 10.1152/physiolgenomics.00093.2020  0.4
2020 Rau CD, Gonzales NM, Bloom JS, Park D, Ayroles J, Palmer AA, Lusis AJ, Zaitlen N. Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis". Plos Genetics. 16: e1009165. PMID 33104702 DOI: 10.1371/journal.pgen.1009165  0.44
2020 Yokota T, Li J, Huang J, Xiong Z, Zhang Q, Chan TW, Ding Y, Rau CD, Sung K, Ren S, Kulkarni RP, Hsiai T, Xiao X, Touma M, Minamisawa S, et al. p38 mitogen-activated protein kinase regulates chamber specific perinatal growth in heart. The Journal of Clinical Investigation. PMID 32573492 DOI: 10.1172/Jci135859  0.4
2020 Rau CD, Lusis AJ, Wang Y. Systems Genetics for Mechanistic Discovery in Heart Diseases. Circulation Research. 126: 1795-1815. PMID 32496909 DOI: 10.1161/Circresaha.119.315863  0.44
2019 Olver TD, Edwards JC, Jurrissen TJ, Veteto AB, Jones JL, Gao C, Rau C, Warren CM, Klutho PJ, Alex L, Ferreira-Nichols SC, Ivey JR, Thorne PK, McDonald KS, Krenz M, et al. Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. Jacc. Basic to Translational Science. 4: 404-421. PMID 31312763 DOI: 10.1016/J.Jacbts.2019.02.004  0.4
2019 Tzimas C, Rau CD, Buergisser PE, Jean-Louis G, Lee K, Chukwuneke J, Dun W, Wang Y, Tsai EJ. WIPI1 is a conserved mediator of right ventricular failure. Jci Insight. 5. PMID 31021818 DOI: 10.1172/Jci.Insight.122929  0.4
2018 Lin LY, Chun-Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, et al. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure. G3 (Bethesda, Md.). PMID 30201759 DOI: 10.1534/G3.118.200655  0.44
2018 Chang SC, Ren S, Rau CD, Wang JJ. Isoproterenol-Induced Heart Failure Mouse Model Using Osmotic Pump Implantation. Methods in Molecular Biology (Clifton, N.J.). 1816: 207-220. PMID 29987822 DOI: 10.1007/978-1-4939-8597-5_16  0.4
2018 Santolini M, Romay MC, Yukhtman CL, Rau CD, Ren S, Saucerman JJ, Wang JJ, Weiss JN, Wang Y, Lusis AJ, Karma A. A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure. Npj Systems Biology and Applications. 4: 12. PMID 29507758 DOI: 10.1038/s41540-018-0046-3  0.44
2017 Wisniewski N, Bondar G, Rau C, Chittoor J, Chang E, Esmaeili A, Cadeiras M, Deng M. Integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support: a prospective observational study. Bmc Medical Genomics. 10: 52. PMID 28851355 DOI: 10.1186/S12920-017-0288-8  0.4
2017 Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, et al. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genetics. PMID 28783163 DOI: 10.1038/Ng.3929  0.44
2017 Gao C, Howard-Quijano K, Rau C, Takamiya T, Song Y, Shivkumar K, Wang Y, Mahajan A. Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction. Plos One. 12: e0177750. PMID 28542617 DOI: 10.1371/Journal.Pone.0177750  0.4
2017 Seldin MM, Kim ED, Romay MC, Li S, Rau CD, Wang JJ, Chella Krishnan K, Wang Y, Deb A, Lusis AJ. Systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00068.2016. PMID 28235788 DOI: 10.1152/Ajpheart.00068.2016  0.44
2017 Rau CD, Civelek M, Pan C, Lusis AJ. A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel. Methods in Molecular Biology (Clifton, N.J.). 1488: 153-188. PMID 27933524 DOI: 10.1007/978-1-4939-6427-7_7  0.44
2016 Rau CD, Romay MC, Tuteryan M, Wang JJ, Santolini M, Ren S, Karma A, Weiss JN, Wang Y, Lusis AJ. Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell Systems. PMID 27866946 DOI: 10.1016/J.Cels.2016.10.016  0.44
2016 Rau CD, Gao C, Wang Y. Deconvolution of the Human Endothelial Transcriptome. Cell Systems. 3: 218-220. PMID 27684186 DOI: 10.1016/J.Cels.2016.09.006  0.4
2016 Wang JJ, Rau C, Avetisyan R, Ren S, Romay MC, Stolin G, Gong KW, Wang Y, Lusis AJ. Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. Plos Genetics. 12: e1006038. PMID 27385019 DOI: 10.1371/Journal.Pgen.1006038  0.4
2016 Karbassi E, Monte E, Chapski DJ, Lopez R, Rosa Garrido M, Kim J, Wisniewski NN, Rau CC, Wang JJ, Weiss JN, Wang Y, Lusis AJ, Vondriska TM. Relationship of Disease-Associated Gene Expression to Cardiac Phenotype is Buffered by Genetic Diversity and Chromatin Regulation. Physiological Genomics. physiolgenomics.0003. PMID 27287924 DOI: 10.1152/Physiolgenomics.00035.2016  0.4
2016 Monte E, Rosa-Garrido M, Karbassi E, Chen H, Lopez R, Rau CD, Wang J, Nelson SF, Wu Y, Stefani E, Lusis AJ, Wang Y, Kurdistani SK, Franklin S, Vondriska TM. Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins HMGB and CTCF: Implications for Transcriptional Regulation. The Journal of Biological Chemistry. PMID 27226577 DOI: 10.1074/Jbc.M116.719633  0.4
2016 Lusis AJ, Seldin M, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber C, Hui ST, Mehrabian M, Norheim F, Pan C, Parks B, Rau C, Smith DJ, et al. The Hybrid Mouse Diversity Panel: A Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits. Journal of Lipid Research. PMID 27099397 DOI: 10.1194/Jlr.R066944  0.4
2016 Sun H, Olson KC, Gao C, Prosdocimo DA, Zhou M, Wang Z, Jeyaraj D, Youn JY, Ren S, Liu Y, Rau CD, Shah S, Ilkayeva O, Gui WJ, Williams NS, et al. Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure. Circulation. PMID 27059949 DOI: 10.1161/Circulationaha.115.020226  0.4
2016 Chen H, Orozco LD, Wang J, Rau CD, Rubbi L, Ren S, Wang Y, Pellegrini M, Lusis AJ, Vondriska TM. DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circulation Research. PMID 26838786 DOI: 10.1161/Circresaha.115.305298  0.44
2016 Wisniewski N, Bondar G, Rau C, Chittoor J, Chang E, Esmaeili A, Deng M. A Gene Expression Biomarker Panel for Predicting Mechanical Circulatory Support Outcomes Journal of Heart and Lung Transplantation. 35. DOI: 10.1016/J.Healun.2016.01.157  0.4
2015 Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y. RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. The Journal of Clinical Investigation. PMID 26619120 DOI: 10.1172/Jci84015  0.4
2015 Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ. High Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda, Md.). PMID 26224782 DOI: 10.1534/G3.115.020784  0.4
2015 Neelankavil J, Rau CD, Wang Y. The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets. Journal of Cardiothoracic and Vascular Anesthesia. 29: 1328-32. PMID 25976605 DOI: 10.1053/J.Jvca.2015.01.031  0.4
2015 Rau CD, Lusis AJ, Wang Y. Genetics of common forms of heart failure: challenges and potential solutions. Current Opinion in Cardiology. 30: 222-7. PMID 25768955 DOI: 10.1097/Hco.0000000000000160  0.4
2015 Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, et al. Genetic architecture of insulin resistance in the mouse. Cell Metabolism. 21: 334-46. PMID 25651185 DOI: 10.1016/J.Cmet.2015.01.002  0.4
2015 Rau CD, Wang J, Avetisyan R, Romay MC, Martin L, Ren S, Wang Y, Lusis AJ. Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circulation. Cardiovascular Genetics. 8: 40-9. PMID 25480693 DOI: 10.1161/Circgenetics.113.000732  0.4
2013 Lu G, Ota A, Ren S, Franklin S, Rau CD, Ping P, Lane TF, Zhou ZH, Reue K, Lusis AJ, Vondriska T, Wang Y. PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Molecular Metabolism. 2: 405-16. PMID 24327956 DOI: 10.1016/J.Molmet.2013.07.005  0.4
2013 Rau CD, Wisniewski N, Orozco LD, Bennett B, Weiss J, Lusis AJ. Maximal information component analysis: a novel non-linear network analysis method. Frontiers in Genetics. 4: 28. PMID 23487572 DOI: 10.3389/Fgene.2013.00028  0.4
2013 Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. Genome-wide association mapping of blood cell traits in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 105-18. PMID 23417284 DOI: 10.1007/S00335-013-9448-0  0.4
2013 Lagarrigue S, Hormozdiari F, Martin LJ, Lecerf F, Hasin Y, Rau C, Hagopian R, Xiao Y, Yan J, Drake TA, Ghazalpour A, Eskin E, Lusis AJ. Limited RNA editing in exons of mouse liver and adipose. Genetics. 193: 1107-15. PMID 23410828 DOI: 10.1534/Genetics.112.149054  0.4
2013 Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, Mehrabian M, Ursell LK, He A, Castellani LW, Zinker B, et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metabolism. 17: 141-52. PMID 23312289 DOI: 10.1016/J.Cmet.2012.12.007  0.4
2012 Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, et al. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 680-92. PMID 22892838 DOI: 10.1007/S00335-012-9411-5  0.4
2012 Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. "Good enough solutions" and the genetics of complex diseases. Circulation Research. 111: 493-504. PMID 22859671 DOI: 10.1161/Circresaha.112.269084  0.4
2011 Mungrue IN, Zhao P, Yao Y, Meng H, Rau C, Havel JV, Gorgels TG, Bergen AA, MacLellan WR, Drake TA, Boström KI, Lusis AJ. Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2806-12. PMID 21979437 DOI: 10.1161/Atvbaha.111.237420  0.44
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