| Year |
Citation |
Score |
| 2022 |
Walewska A, Kosikowska-Adamus P, Tomczykowska M, Jaroszewski B, Prahl A, Bulaj G. Improving Fmoc Solid Phase Synthesis of Human Beta Defensin 3. International Journal of Molecular Sciences. 23. PMID 36293413 DOI: 10.3390/ijms232012562 |
0.373 |
|
| 2017 |
Metcalf CS, Klein BD, McDougle DR, Zhang L, Kaufmann D, Bulaj G, White HS. Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics. Epilepsia. PMID 28098336 DOI: 10.1111/Epi.13647 |
0.358 |
|
| 2016 |
Walls AB, Flynn SP, West PJ, Müller MS, Bak LK, Bulaj G, Schousboe A, White HS. The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission. Epilepsy Research. 121: 55-63. PMID 26894875 DOI: 10.1016/J.Eplepsyres.2016.01.006 |
0.317 |
|
| 2016 |
Green BR, Gajewiak J, Chhabra S, Skalicky JJ, Zhang MM, Rivier JE, Bulaj G, Olivera BM, Yoshikami D, Norton RS. Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ. The Journal of Biological Chemistry. PMID 26817840 DOI: 10.1074/Jbc.M115.697672 |
0.398 |
|
| 2015 |
Zhang MM, Gajewiak J, Azam L, Bulaj G, Olivera BM, Yoshikami D. Probing the Redox States of Sodium Channel Cysteines at the Binding Site of μO§-Conotoxin GVIIJ. Biochemistry. 54: 3911-20. PMID 26039939 DOI: 10.1021/Acs.Biochem.5B00390 |
0.45 |
|
| 2015 |
Lee HK, Zhang L, Smith MD, Walewska A, Vellore NA, Baron R, McIntosh JM, White HS, Olivera BM, Bulaj G. A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties. Frontiers in Pharmacology. 6: 11. PMID 25713532 DOI: 10.3389/Fphar.2015.00011 |
0.373 |
|
| 2014 |
Green BR, Bulaj G, Norton RS. Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity. Future Medicinal Chemistry. 6: 1677-98. PMID 25406007 DOI: 10.4155/Fmc.14.107 |
0.425 |
|
| 2014 |
Green BR, Zhang MM, Chhabra S, Robinson SD, Wilson MJ, Redding A, Olivera BM, Yoshikami D, Bulaj G, Norton RS. Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3. The Febs Journal. 281: 2885-98. PMID 24814369 DOI: 10.1111/Febs.12835 |
0.454 |
|
| 2014 |
Platt RJ, Curtice KJ, Twede VD, Watkins M, Gruszczy?ski P, Bulaj G, Horvath MP, Olivera BM. From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypes. Toxicon : Official Journal of the International Society On Toxinology. 81: 67-79. PMID 24508768 DOI: 10.1016/J.Toxicon.2014.01.016 |
0.372 |
|
| 2014 |
Gajewiak J, Azam L, Imperial J, Walewska A, Green BR, Bandyopadhyay PK, Raghuraman S, Ueberheide B, Bern M, Zhou HM, Minassian NA, Hagan RH, Flinspach M, Liu Y, Bulaj G, et al. A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ. Proceedings of the National Academy of Sciences of the United States of America. 111: 2758-63. PMID 24497506 DOI: 10.1073/Pnas.1324189111 |
0.499 |
|
| 2013 |
Steiner AM, Bulaj G, Puillandre N. On the importance of oxidative folding in the evolution of conotoxins: cysteine codon preservation through gene duplication and adaptation. Plos One. 8: e78456. PMID 24244311 DOI: 10.1371/Journal.Pone.0078456 |
0.66 |
|
| 2013 |
Walewska A, Han TS, Zhang MM, Yoshikami D, Bulaj G, Rolka K. Expanding chemical diversity of conotoxins: peptoid-peptide chimeras of the sodium channel blocker μ-KIIIA and its selenopeptide analogues. European Journal of Medicinal Chemistry. 65: 144-150. PMID 23707919 DOI: 10.1016/J.Ejmech.2013.04.041 |
0.48 |
|
| 2013 |
Kuang Z, Zhang MM, Gupta K, Gajewiak J, Gulyas J, Balaram P, Rivier JE, Olivera BM, Yoshikami D, Bulaj G, Norton RS. Mammalian neuronal sodium channel blocker μ-conotoxin BuIIIB has a structured N-terminus that influences potency. Acs Chemical Biology. 8: 1344-51. PMID 23557677 DOI: 10.1021/Cb300674X |
0.472 |
|
| 2013 |
Zhang L, Klein BD, Metcalf CS, Smith MD, McDougle DR, Lee HK, White HS, Bulaj G. Incorporation of monodisperse oligoethyleneglycol amino acids into anticonvulsant analogues of galanin and neuropeptide y provides peripherally acting analgesics. Molecular Pharmaceutics. 10: 574-85. PMID 23259957 DOI: 10.1021/Mp300236V |
0.33 |
|
| 2013 |
Green BR, Klein BD, Lee HK, Smith MD, Steve White H, Bulaj G. Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling. Bioorganic & Medicinal Chemistry. 21: 303-10. PMID 23176753 DOI: 10.1016/J.Bmc.2012.10.026 |
0.383 |
|
| 2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F |
0.388 |
|
| 2013 |
Zhang MM, Wilson MJ, Azam L, Gajewiak J, Rivier JE, Bulaj G, Olivera BM, Yoshikami D. Co-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins. British Journal of Pharmacology. 168: 1597-610. PMID 23146020 DOI: 10.1111/Bph.12051 |
0.328 |
|
| 2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A |
0.368 |
|
| 2012 |
Khoo KK, Gupta K, Green BR, Zhang MM, Watkins M, Olivera BM, Balaram P, Yoshikami D, Bulaj G, Norton RS. Distinct disulfide isomers of μ-conotoxins KIIIA and KIIIB block voltage-gated sodium channels. Biochemistry. 51: 9826-35. PMID 23167564 DOI: 10.1021/Bi301256S |
0.335 |
|
| 2012 |
Safavi-Hemami H, Gorasia DG, Steiner AM, Williamson NA, Karas JA, Gajewiak J, Olivera BM, Bulaj G, Purcell AW. Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails. The Journal of Biological Chemistry. 287: 34288-303. PMID 22891240 DOI: 10.1074/Jbc.M112.366781 |
0.705 |
|
| 2012 |
Gowd KH, Blais KD, Elmslie KS, Steiner AM, Olivera BM, Bulaj G. Dissecting a role of evolutionary-conserved but noncritical disulfide bridges in cysteine-rich peptides using ω-conotoxin GVIA and its selenocysteine analogs. Biopolymers. 98: 212-23. PMID 22782563 DOI: 10.1002/Bip.22047 |
0.718 |
|
| 2012 |
Singer HM, Erhardt M, Steiner AM, Zhang MM, Yoshikami D, Bulaj G, Olivera BM, Hughes KT. Selective purification of recombinant neuroactive peptides using the flagellar type III secretion system. Mbio. 3. PMID 22647788 DOI: 10.1128/Mbio.00115-12 |
0.694 |
|
| 2012 |
Gowd KH, Han TS, Twede V, Gajewiak J, Smith MD, Watkins M, Platt RJ, Toledo G, White HS, Olivera BM, Bulaj G. Conantokins derived from the Asprella clade impart conRl-B, an N-methyl d-aspartate receptor antagonist with a unique selectivity profile for NR2B subunits. Biochemistry. 51: 4685-92. PMID 22594498 DOI: 10.1021/Bi300055N |
0.341 |
|
| 2012 |
Platt RJ, Han TS, Green BR, Smith MD, Skalicky J, Gruszczynski P, White HS, Olivera B, Bulaj G, Gajewiak J. Stapling mimics noncovalent interactions of γ-carboxyglutamates in conantokins, peptidic antagonists of N-methyl-D-aspartic acid receptors. The Journal of Biological Chemistry. 287: 20727-36. PMID 22518838 DOI: 10.1074/Jbc.M112.350462 |
0.484 |
|
| 2012 |
Steiner AM, Woycechowsky KJ, Olivera BM, Bulaj G. Reagentless oxidative folding of disulfide-rich peptides catalyzed by an intramolecular diselenide. Angewandte Chemie (International Ed. in English). 51: 5580-4. PMID 22454362 DOI: 10.1002/Anie.201200062 |
0.699 |
|
| 2012 |
Zhang L, Bulaj G. Converting peptides into drug leads by lipidation. Current Medicinal Chemistry. 19: 1602-18. PMID 22376031 DOI: 10.2174/092986712799945003 |
0.433 |
|
| 2012 |
Robertson CR, Pruess TH, Grussendorf E, White HS, Bulaj G. Generating orally active galanin analogues with analgesic activities. Chemmedchem. 7: 903-9. PMID 22374865 DOI: 10.1002/Cmdc.201100574 |
0.348 |
|
| 2011 |
Green BR, Smith M, White KL, White HS, Bulaj G. Analgesic neuropeptide W suppresses seizures in the brain revealed by rational repositioning and peptide engineering. Acs Chemical Neuroscience. 2: 51-6. PMID 22826747 DOI: 10.1021/Cn1000974 |
0.361 |
|
| 2011 |
Khoo KK, Wilson MJ, Smith BJ, Zhang MM, Gulyas J, Yoshikami D, Rivier JE, Bulaj G, Norton RS. Lactam-stabilized helical analogues of the analgesic μ-conotoxin KIIIA. Journal of Medicinal Chemistry. 54: 7558-66. PMID 21962108 DOI: 10.1021/Jm200839A |
0.435 |
|
| 2011 |
Wilson MJ, Zhang MM, Azam L, Olivera BM, Bulaj G, Yoshikami D. Navβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIB. The Journal of Pharmacology and Experimental Therapeutics. 338: 687-93. PMID 21586605 DOI: 10.1124/Jpet.110.178343 |
0.326 |
|
| 2011 |
Robertson CR, Flynn SP, White HS, Bulaj G. Anticonvulsant neuropeptides as drug leads for neurological diseases. Natural Product Reports. 28: 741-62. PMID 21340067 DOI: 10.1039/C0Np00048E |
0.343 |
|
| 2011 |
Walewska A, Jaśkiewicz A, Bulaj G, Rolka K. Selenopeptide analogs of EETI-II retain potent trypsin inhibitory activities. Chemical Biology & Drug Design. 77: 93-97. PMID 20958922 DOI: 10.1111/J.1747-0285.2010.01046.X |
0.44 |
|
| 2011 |
Steiner AM, Bulaj G. Optimization of oxidative folding methods for cysteine-rich peptides: a study of conotoxins containing three disulfide bridges. Journal of Peptide Science : An Official Publication of the European Peptide Society. 17: 1-7. PMID 20814907 DOI: 10.1002/Psc.1283 |
0.702 |
|
| 2010 |
McIntosh JA, Robertson CR, Agarwal V, Nair SK, Bulaj GW, Schmidt EW. Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst. Journal of the American Chemical Society. 132: 15499-501. PMID 20961047 DOI: 10.1021/Ja1067806 |
0.454 |
|
| 2010 |
Han TS, Zhang MM, Gowd KH, Walewska A, Yoshikami D, Olivera BM, Bulaj G. Disulfide-Depleted Selenoconopeptides: a Minimalist Strategy to Oxidative Folding of Cysteine-Rich Peptides. Acs Medicinal Chemistry Letters. 1: 140-144. PMID 20676359 DOI: 10.1021/Ml900017Q |
0.523 |
|
| 2010 |
Green BR, White KL, McDougle DR, Zhang L, Klein B, Scholl EA, Pruess TH, White HS, Bulaj G. Introduction of lipidization-cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 486-95. PMID 20645434 DOI: 10.1002/Psc.1266 |
0.413 |
|
| 2010 |
Gowd KH, Watkins M, Twede VD, Bulaj GW, Olivera BM. Characterization of conantokin Rl-A: molecular phylogeny as structure/function study. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 375-82. PMID 20572027 DOI: 10.1002/Psc.1249 |
0.465 |
|
| 2010 |
Zhang MM, Han TS, Olivera BM, Bulaj G, Yoshikami D. μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels. Biochemistry. 49: 4804-12. PMID 20459109 DOI: 10.1021/Bi100207K |
0.399 |
|
| 2010 |
Zhang MM, Gruszczynski P, Walewska A, Bulaj G, Olivera BM, Yoshikami D. Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin. Journal of Neurophysiology. 104: 88-97. PMID 20410356 DOI: 10.1152/Jn.00145.2010 |
0.414 |
|
| 2010 |
Gowd KH, Yarotskyy V, Elmslie KS, Skalicky JJ, Olivera BM, Bulaj G. Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA. Biochemistry. 49: 2741-52. PMID 20175537 DOI: 10.1021/Bi902137C |
0.534 |
|
| 2010 |
Safavi-Hemami H, Bulaj G, Olivera BM, Williamson NA, Purcell AW. Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins. The Journal of Biological Chemistry. 285: 12735-46. PMID 20147296 DOI: 10.1074/Jbc.M109.078691 |
0.493 |
|
| 2010 |
Robertson CR, Scholl EA, Pruess TH, Green BR, White HS, Bulaj G. Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery. Journal of Medicinal Chemistry. 53: 1871-5. PMID 20121116 DOI: 10.1021/Jm9018349 |
0.313 |
|
| 2010 |
Han TS, Zhang MM, Gowd KH, Walewska A, Yoshikami D, Olivera BM, Bulaj G. Disulfide-depleted selenoconopeptides: Simplified oxidative folding of cysteine-rich peptides Acs Medicinal Chemistry Letters. 1: 140-144. DOI: 10.1021/ml900017q |
0.375 |
|
| 2009 |
Lee HK, Smith MD, Smith BJ, Grussendorf J, Xu L, Gillies RJ, White HS, Bulaj G. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. Acs Chemical Biology. 4: 659-71. PMID 19634861 DOI: 10.1021/Cb900045C |
0.393 |
|
| 2009 |
Twede VD, Miljanich G, Olivera BM, Bulaj G. Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads. Current Opinion in Drug Discovery & Development. 12: 231-9. PMID 19333868 |
0.327 |
|
| 2009 |
Twede VD, Teichert RW, Walker CS, Gruszczy?ski P, Ka?mierkiewicz R, Bulaj G, Olivera BM. Conantokin-Br from Conus brettinghami and selectivity determinants for the NR2D subunit of the NMDA receptor. Biochemistry. 48: 4063-73. PMID 19309162 DOI: 10.1021/Bi802259A |
0.392 |
|
| 2009 |
Zhang L, Lee HK, Pruess TH, White HS, Bulaj G. Synthesis and applications of polyamine amino acid residues: improving the bioactivity of an analgesic neuropeptide, neurotensin. Journal of Medicinal Chemistry. 52: 1514-7. PMID 19236044 DOI: 10.1021/Jm801481Y |
0.337 |
|
| 2009 |
Zhang MM, McArthur JR, Azam L, Bulaj G, Olivera BM, French RJ, Yoshikami D. Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels. Channels (Austin, Tex.). 3: 32-8. PMID 19221510 DOI: 10.4161/Chan.3.1.7500 |
0.462 |
|
| 2009 |
Walewska A, Zhang MM, Skalicky JJ, Yoshikami D, Olivera BM, Bulaj G. Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins. Angewandte Chemie (International Ed. in English). 48: 2221-4. PMID 19206132 DOI: 10.1002/Anie.200806085 |
0.412 |
|
| 2009 |
Zhang L, Robertson CR, Green BR, Pruess TH, White HS, Bulaj G. Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues. Journal of Medicinal Chemistry. 52: 1310-6. PMID 19199479 DOI: 10.1021/Jm801397W |
0.383 |
|
| 2009 |
Lee HK, Zhang L, Smith MD, White HS, Bulaj G. Glycosylated neurotensin analogues exhibit sub-picomolar anticonvulsant potency in a pharmacoresistant model of epilepsy. Chemmedchem. 4: 400-5. PMID 19173215 DOI: 10.1002/Cmdc.200800421 |
0.309 |
|
| 2009 |
Khoo KK, Feng ZP, Smith BJ, Zhang MM, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion. Biochemistry. 48: 1210-9. PMID 19170536 DOI: 10.1021/Bi801998A |
0.372 |
|
| 2009 |
Han TS, Zhang MM, Walewska A, Gruszczynski P, Robertson CR, Cheatham TE, Yoshikami D, Olivera BM, Bulaj G. Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics. Chemmedchem. 4: 406-14. PMID 19107760 DOI: 10.1002/Cmdc.200800292 |
0.436 |
|
| 2009 |
Holford M, Zhang MM, Gowd KH, Azam L, Green BR, Watkins M, Ownby JP, Yoshikami D, Bulaj G, Olivera BM. Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus. Toxicon : Official Journal of the International Society On Toxinology. 53: 90-8. PMID 18950653 DOI: 10.1016/J.Toxicon.2008.10.017 |
0.419 |
|
| 2009 |
McArthur JR, Zhang M, Azam L, Luo S, Olivera BM, Yoshikami D, Bulaj G, Levinson SR, French RJ. Molecular Determinants of μ-Conotoxin KIIIA Block of Voltage-Gated Sodium Channels Biophysical Journal. 96: 248a. DOI: 10.1016/J.Bpj.2008.12.1219 |
0.344 |
|
| 2008 |
Bulaj G, Green BR, Lee HK, Robertson CR, White K, Zhang L, Sochanska M, Flynn SP, Scholl EA, Pruess TH, Smith MD, White HS. Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities. Journal of Medicinal Chemistry. 51: 8038-47. PMID 19053761 DOI: 10.1021/Jm801088X |
0.365 |
|
| 2008 |
Walewska A, Skalicky JJ, Davis DR, Zhang MM, Lopez-Vera E, Watkins M, Han TS, Yoshikami D, Olivera BM, Bulaj G. NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA. Journal of the American Chemical Society. 130: 14280-6. PMID 18831583 DOI: 10.1021/Ja804303P |
0.453 |
|
| 2008 |
Yao S, Zhang MM, Yoshikami D, Azam L, Olivera BM, Bulaj G, Norton RS. Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA. Biochemistry. 47: 10940-9. PMID 18798648 DOI: 10.1021/Bi801010U |
0.413 |
|
| 2008 |
Han TS, Teichert RW, Olivera BM, Bulaj G. Conus venoms - a rich source of peptide-based therapeutics. Current Pharmaceutical Design. 14: 2462-79. PMID 18781995 DOI: 10.2174/138161208785777469 |
0.377 |
|
| 2008 |
Bulaj G. Integrating the discovery pipeline for novel compounds targeting ion channels Current Opinion in Chemical Biology. 12: 441-447. PMID 18678277 DOI: 10.1016/J.Cbpa.2008.07.012 |
0.341 |
|
| 2008 |
Gowd KH, Twede V, Watkins M, Krishnan KS, Teichert RW, Bulaj G, Olivera BM. Conantokin-P, an unusual conantokin with a long disulfide loop. Toxicon : Official Journal of the International Society On Toxinology. 52: 203-13. PMID 18586049 DOI: 10.1016/J.Toxicon.2008.04.178 |
0.438 |
|
| 2008 |
Fiedler B, Zhang MM, Buczek O, Azam L, Bulaj G, Norton RS, Olivera BM, Yoshikami D. Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7. Biochemical Pharmacology. 75: 2334-44. PMID 18486102 DOI: 10.1016/J.Bcp.2008.03.019 |
0.369 |
|
| 2008 |
Lopez-Vera E, Walewska A, Skalicky JJ, Olivera BM, Bulaj G. Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins. Biochemistry. 47: 1741-51. PMID 18189422 DOI: 10.1021/Bi701934M |
0.467 |
|
| 2008 |
Lluisma AO, López-Vera E, Bulaj G, Watkins M, Olivera BM. Characterization of a novel psi-conotoxin from Conus parius Reeve. Toxicon : Official Journal of the International Society On Toxinology. 51: 174-80. PMID 18054976 DOI: 10.1016/J.Toxicon.2007.07.009 |
0.444 |
|
| 2008 |
Bulaj G, Olivera BM. Folding of conotoxins: formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides. Antioxidants & Redox Signaling. 10: 141-55. PMID 17961068 DOI: 10.1089/Ars.2007.1856 |
0.499 |
|
| 2007 |
Teichert RW, Jimenez EC, Twede V, Watkins M, Hollmann M, Bulaj G, Olivera BM. Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 282: 36905-13. PMID 17962189 DOI: 10.1074/Jbc.M706611200 |
0.431 |
|
| 2007 |
Zhang MM, Green BR, Catlin P, Fiedler B, Azam L, Chadwick A, Terlau H, McArthur JR, French RJ, Gulyas J, Rivier JE, Smith BJ, Norton RS, Olivera BM, Yoshikami D, ... Bulaj G, et al. Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. The Journal of Biological Chemistry. 282: 30699-706. PMID 17724025 DOI: 10.1074/Jbc.M704616200 |
0.326 |
|
| 2007 |
Buczek O, Wei D, Babon JJ, Yang X, Fiedler B, Chen P, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Structure and sodium channel activity of an excitatory I1-superfamily conotoxin. Biochemistry. 46: 9929-40. PMID 17696362 DOI: 10.1021/Bi701925D |
0.408 |
|
| 2007 |
Green BR, Catlin P, Zhang MM, Fiedler B, Bayudan W, Morrison A, Norton RS, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity. Chemistry & Biology. 14: 399-407. PMID 17462575 DOI: 10.1016/J.Chembiol.2007.02.009 |
0.467 |
|
| 2007 |
Buczek O, Green BR, Bulaj G. Albumin is a redox-active crowding agent that promotes oxidative folding of cysteine-rich peptides. Biopolymers. 88: 8-19. PMID 17061249 DOI: 10.1002/Bip.20615 |
0.488 |
|
| 2006 |
Dy CY, Buczek P, Imperial JS, Bulaj G, Horvath MP. Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snail. Acta Crystallographica. Section D, Biological Crystallography. 62: 980-90. PMID 16929098 DOI: 10.1107/S0907444906021123 |
0.363 |
|
| 2006 |
Bulaj G, Zhang MM, Green BR, Fiedler B, Layer RT, Wei S, Nielsen JS, Low SJ, Klein BD, Wagstaff JD, Chicoine L, Harty TP, Terlau H, Yoshikami D, Olivera BM. Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity. Biochemistry. 45: 7404-14. PMID 16752929 DOI: 10.1021/Bi060159+ |
0.409 |
|
| 2006 |
Zhang MM, Fiedler B, Green BR, Catlin P, Watkins M, Garrett JE, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels. Biochemistry. 45: 3723-32. PMID 16533055 DOI: 10.1021/Bi052162J |
0.398 |
|
| 2006 |
Zorn S, Leipold E, Hansel A, Bulaj G, Olivera BM, Terlau H, Heinemann SH. The muO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3. Febs Letters. 580: 1360-4. PMID 16458302 DOI: 10.1016/J.Febslet.2006.01.057 |
0.34 |
|
| 2006 |
Green BR, Bulaj G. Oxidative folding of conotoxins in immobilized systems. Protein and Peptide Letters. 13: 67-70. PMID 16454672 DOI: 10.2174/092986606774502162 |
0.446 |
|
| 2005 |
Buczek O, Bulaj G, Olivera BM. Conotoxins and the posttranslational modification of secreted gene products. Cellular and Molecular Life Sciences : Cmls. 62: 3067-79. PMID 16314929 DOI: 10.1007/S00018-005-5283-0 |
0.464 |
|
| 2005 |
West PJ, Bulaj G, Yoshikami D. Effects of δ-Conotoxins PVIA and SVIE on Sodium Channels in the Amphibian Sympathetic Nervous System Journal of Neurophysiology. 94: 3916-3924. PMID 16107523 DOI: 10.1152/Jn.01304.2004 |
0.42 |
|
| 2005 |
Buczek O, Yoshikami D, Watkins M, Bulaj G, Jimenez EC, Olivera BM. Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily. The Febs Journal. 272: 4178-88. PMID 16098199 DOI: 10.1111/J.1742-4658.2005.04830.X |
0.349 |
|
| 2005 |
Bulaj G, West PJ, Garrett JE, Watkins M, Marsh M, Zhang MM, Norton RS, Smith BJ, Yoshikami D, Olivera BM. Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels. Biochemistry. 44: 7259-65. PMID 15882064 DOI: 10.1021/BI0473408 |
0.479 |
|
| 2005 |
Fuller E, Green BR, Catlin P, Buczek O, Nielsen JS, Olivera BM, Bulaj G. Oxidative folding of conotoxins sharing an identical disulfide bridging framework. The Febs Journal. 272: 1727-38. PMID 15794759 DOI: 10.1111/J.1742-4658.2005.04602.X |
0.434 |
|
| 2005 |
Garrett JE, Buczek O, Watkins M, Olivera BM, Bulaj G. Biochemical and gene expression analyses of conotoxins in Conus textile venom ducts. Biochemical and Biophysical Research Communications. 328: 362-7. PMID 15670792 DOI: 10.1016/J.Bbrc.2004.12.178 |
0.317 |
|
| 2005 |
Buczek P, Buczek O, Bulaj G. Total chemical synthesis and oxidative folding of δ‐conotoxin PVIA containing an N‐terminal propeptide Biopolymers. 80: 50-57. PMID 15641120 DOI: 10.1002/Bip.20211 |
0.459 |
|
| 2005 |
Bulaj G. Formation of disulfide bonds in proteins and peptides Biotechnology Advances. 23: 87-92. PMID 15610970 DOI: 10.1016/J.Biotechadv.2004.09.002 |
0.425 |
|
| 2005 |
Buczek O, Yoshikami D, Bulaj G, Jimenez EC, Olivera BM. Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide. The Journal of Biological Chemistry. 280: 4247-53. PMID 15561705 DOI: 10.1074/Jbc.M405835200 |
0.404 |
|
| 2004 |
Teichert RW, Rivier J, Dykert J, Cervini L, Gulyas J, Bulaj G, Ellison M, Olivera BM. AlphaA-Conotoxin OIVA defines a new alphaA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors. Toxicon : Official Journal of the International Society On Toxinology. 44: 207-14. PMID 15246771 DOI: 10.1016/J.Toxicon.2004.05.026 |
0.468 |
|
| 2004 |
Nielsen JS, Buczek P, Bulaj G. Cosolvent‐assisted oxidative folding of a bicyclic α‐conotoxin ImI Journal of Peptide Science. 10: 249-256. PMID 15160836 DOI: 10.1002/Psc.531 |
0.405 |
|
| 2004 |
Bulaj G, Koehn RE, Goldenberg DP. Alteration of the disulfide-coupled folding pathway of BPTI by circular permutation Protein Science. 13: 1182-1196. PMID 15096625 DOI: 10.1110/Ps.03563704 |
0.34 |
|
| 2004 |
Buczek O, Olivera BM, Bulaj G. Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor. Biochemistry. 43: 1093-101. PMID 14744155 DOI: 10.1021/Bi0354233 |
0.443 |
|
| 2003 |
Bulaj G, Buczek O, Goodsell I, Jimenez EC, Kranski J, Nielsen JS, Garrett JE, Olivera BM. Efficient oxidative folding of conotoxins and the radiation of venomous cone snails. Proceedings of the National Academy of Sciences of the United States of America. 100: 14562-8. PMID 14573706 DOI: 10.1073/Pnas.2335845100 |
0.493 |
|
| 2003 |
Keizer DW, West PJ, Lee EF, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA. The Journal of Biological Chemistry. 278: 46805-13. PMID 12970353 DOI: 10.1074/Jbc.M309222200 |
0.423 |
|
| 2003 |
Van Horn JD, Bulaj G, Goldenberg DP, Burrows CJ. The Cys-Xaa-His metal-binding motif: [N] versus [S] coordination and nickel-mediated formation of cysteinyl sulfinic acid. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 8: 601-10. PMID 12827456 DOI: 10.1007/S00775-003-0454-7 |
0.423 |
|
| 2003 |
DeLa Cruz R, Whitby FG, Buczek O, Bulaj G. Detergent-assisted oxidative folding of delta-conotoxins. The Journal of Peptide Research : Official Journal of the American Peptide Society. 61: 202-12. PMID 12605605 DOI: 10.1034/J.1399-3011.2003.00048.X |
0.389 |
|
| 2002 |
West PJ, Bulaj G, Garrett JE, Olivera BM, Yoshikami D. Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons. Biochemistry. 41: 15388-93. PMID 12484778 DOI: 10.1021/Bi0265628 |
0.45 |
|
| 2002 |
Miles LA, Dy CY, Nielsen J, Barnham KJ, Hinds MG, Olivera BM, Bulaj G, Norton RS. Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif. The Journal of Biological Chemistry. 277: 43033-40. PMID 12193600 DOI: 10.1074/Jbc.M206690200 |
0.427 |
|
| 2002 |
Price-Carter M, Bulaj G, Goldenberg DP. Initial disulfide formation steps in the folding of an ω-conotoxin Biochemistry. 41: 3507-3519. PMID 11876659 DOI: 10.1021/Bi012033C |
0.387 |
|
| 2002 |
Maillo M, Aguilar MB, Lopéz-Vera E, Craig AG, Bulaj G, Olivera BM, Heimer de la Cotera EP. Conorfamide, a Conus venom peptide belonging to the RFamide family of neuropeptides. Toxicon : Official Journal of the International Society On Toxinology. 40: 401-7. PMID 11738233 DOI: 10.1016/S0041-0101(01)00176-3 |
0.46 |
|
| 2001 |
Bulaj G, DeLaCruz R, Azimi-Zonooz A, West P, Watkins M, Yoshikami D, Olivera BM. Delta-conotoxin structure/function through a cladistic analysis. Biochemistry. 40: 13201-8. PMID 11683628 DOI: 10.1021/Bi010683A |
0.428 |
|
| 2001 |
Bulaj G, Goldenberg DP. Mutational analysis of hydrogen bonding residues in the BPTI folding pathway. Journal of Molecular Biology. 313: 639-656. PMID 11676545 DOI: 10.1006/Jmbi.2001.5046 |
0.348 |
|
| 2001 |
Bulaj G, Goldenberg DP. φ-Values for BPTI folding intermediates and implications for transition state analysis Nature Structural & Molecular Biology. 8: 326-330. PMID 11276252 DOI: 10.1038/86200 |
0.36 |
|
| 2000 |
Jones RM, Bulaj G. Conotoxins - new vistas for peptide therapeutics. Current Pharmaceutical Design. 6: 1249-85. PMID 10903392 DOI: 10.2174/1381612003399653 |
0.463 |
|
| 2000 |
McIntosh JM, Corpuz GO, Layer RT, Garrett JE, Wagstaff JD, Bulaj G, Vyazovkina A, Yoshikami D, Cruz LJ, Olivera BM. Isolation and characterization of a novel conus peptide with apparent antinociceptive activity. The Journal of Biological Chemistry. 275: 32391-7. PMID 10900201 DOI: 10.1074/Jbc.M003619200 |
0.459 |
|
| 1999 |
Bulaj G, Goldenberg DP. Early events in the disulfide-coupled folding of BPTI. Protein Science. 8: 1825-1842. PMID 10493584 DOI: 10.1110/Ps.8.9.1825 |
0.39 |
|
| 1998 |
Bulaj G, Kortemme T, Goldenberg DP. Ionization-reactivity relationships for cysteine thiols in polypeptides. Biochemistry. 37: 8965-72. PMID 9636038 DOI: 10.1021/Bi973101R |
0.396 |
|
| 1994 |
Otlewski J, Zbyryt T, Dryjanski M, Bulaj G, Wilusz T. Single peptide bond hydrolysis/resynthesis in squash inhibitors of serine proteinases. 2. Limited proteolysis of Curcurbita maxima trypsin inhibitor I by pepsin. Biochemistry. 33: 208-213. PMID 8286342 DOI: 10.1021/Bi00167A027 |
0.357 |
|
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