Robert A. Weinberg, Ph.D. - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
oncogenes
Website:
https://biology.mit.edu/people/robert_weinberg

319 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lambert AW, Zhang Y, Weinberg RA. Publisher Correction: Cell-intrinsic and microenvironmental determinants of metastatic colonization. Nature Cell Biology. PMID 38926507 DOI: 10.1038/s41556-024-01458-z  0.334
2024 Lambert AW, Zhang Y, Weinberg RA. Cell-intrinsic and microenvironmental determinants of metastatic colonization. Nature Cell Biology. 26: 687-697. PMID 38714854 DOI: 10.1038/s41556-024-01409-8  0.372
2022 Lambert AW, Fiore C, Chutake Y, Verhaar ER, Strasser PC, Chen MW, Farouq D, Das S, Li X, Eaton EN, Zhang Y, Liu Donaher J, Engstrom I, Reinhardt F, Yuan B, ... ... Weinberg RA, et al. ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells. Developmental Cell. 57: 2714-2730.e8. PMID 36538894 DOI: 10.1016/j.devcel.2022.11.015  0.384
2022 Zhang Y, Donaher JL, Das S, Li X, Reinhardt F, Krall JA, Lambert AW, Thiru P, Keys HR, Khan M, Hofree M, Wilson MM, Yedier-Bayram O, Lack NA, Onder TT, ... ... Weinberg RA, et al. Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis. Nature Cell Biology. PMID 35411083 DOI: 10.1038/s41556-022-00877-0  0.337
2021 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, ... ... Weinberg RA, et al. Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 34654908 DOI: 10.1038/s41580-021-00428-9  0.489
2021 Hamza B, Miller AB, Meier L, Stockslager M, Ng SR, King EM, Lin L, DeGouveia KL, Mulugeta N, Calistri NL, Strouf H, Bray C, Rodriguez F, Freed-Pastor WA, Chin CR, ... ... Weinberg RA, et al. Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice. Nature Communications. 12: 5680. PMID 34584084 DOI: 10.1038/s41467-021-25917-5  0.577
2020 Zou Y, Henry WS, Ricq EL, Graham ET, Phadnis VV, Maretich P, Paradkar S, Boehnke N, Deik AA, Reinhardt F, Eaton JK, Ferguson B, Wang W, Fairman J, Keys HR, ... ... Weinberg RA, et al. Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. Nature. PMID 32939090 DOI: 10.1038/S41586-020-2732-8  0.38
2020 Wilson MM, Weinberg RA, Lees JA, Guen VJ. Emerging Mechanisms by which EMT Programs Control Stemness. Trends in Cancer. PMID 32312682 DOI: 10.1016/J.Trecan.2020.03.011  0.355
2020 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, ... ... Weinberg RA, et al. Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 32300252 DOI: 10.1038/S41580-020-0237-9  0.573
2020 Zhang S, Iyer S, Ran H, Wei W, Weinberg RA, Neel BG. Abstract PR12: Genetic aberrations dictate distinct tumor immune landscape and chemosensitivity in HGSOC Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-Pr12  0.376
2020 Lambert A, Fiore C, Chutake Y, Verhaar E, Chen MW, Donaher J, Reinhardt F, Engstrom I, Yuan B, Bierie B, Farouq D, Carulli J, Olson E, Guenther M, Weinberg R. Abstract P4-04-02: Epigenomic analysis of cancer stem cells (CSCs) from triple-negative breast cancer (TNBC) reveals p63 and p73 as core metastasis drivers Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-04-02  0.389
2020 Böpple K, Dong M, Kleih M, Gaißler A, Oren Y, Henry WS, Oren M, Aylon Y, Winkler B, Regev A, Weinberg RA, Kopp H, Aulitzky WE, Essmann F. Abstract 4320: Ovarian cancer persister cells are characterized by enhanced ER stress gene expression correlating with poor survival Endocrinology. DOI: 10.1158/1538-7445.Am2020-4320  0.326
2019 Shibue T, Reinhardt F, Weinberg RA. Syndecan-mediated ligation of ECM proteins triggers proliferative arrest of disseminated tumor cells. Cancer Research. PMID 31481497 DOI: 10.1158/0008-5472.Can-19-1165  0.418
2019 Rashidian M, LaFleur MW, Verschoor VL, Dongre A, Zhang Y, Nguyen TH, Kolifrath S, Aref AR, Lau CJ, Paweletz CP, Bu X, Freeman GJ, Barrasa MI, Weinberg RA, Sharpe AH, et al. Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade. Proceedings of the National Academy of Sciences of the United States of America. PMID 31375632 DOI: 10.1073/Pnas.1905005116  0.406
2019 Weinberg RA. How TP53 (almost) became an oncogene. Journal of Molecular Cell Biology. PMID 31282927 DOI: 10.1093/Jmcb/Mjz061  0.317
2019 Derynck R, Weinberg RA. EMT and Cancer: More Than Meets the Eye. Developmental Cell. 49: 313-316. PMID 31063750 DOI: 10.1016/J.Devcel.2019.04.026  0.333
2019 Kröger C, Afeyan A, Mraz J, Eaton EN, Reinhardt F, Khodor YL, Thiru P, Bierie B, Ye X, Burge CB, Weinberg RA. Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30910979 DOI: 10.1073/Pnas.1812876116  0.346
2019 Weinberg RA. Abstract SY23-02: Actions of the EMT Program in fostering malignant progression Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Sy23-02  0.415
2019 Zhang S, Iyer S, Ran H, wei W, Weinberg RA, Neel BG. Abstract PR05: Development of new immune therapy combinations for ovarian cancer using genetically defined organoid platform Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Pr05  0.368
2019 Iyer S, Zhang S, Farkkila A, Smith S, Pepin D, Mohan R, Reinhardt F, Xia T, Chavarria TE, Hoefsmit E, Pathania S, Zhou Y, Elias KM, Neel BG, Weinberg RA. Abstract PR04: The genomic architecture of serous carcinomas shapes the tumor microenvironment and modulates responses to targeted and immunotherapies Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Pr04  0.379
2018 Dongre A, Weinberg RA. New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer. Nature Reviews. Molecular Cell Biology. PMID 30459476 DOI: 10.1038/S41580-018-0080-4  0.43
2018 Castaño Z, San Juan BP, Spiegel A, Pant A, DeCristo MJ, Laszewski T, Ubellacker JM, Janssen SR, Dongre A, Reinhardt F, Henderson A, Del Rio AG, Gifford AM, Herbert ZT, Hutchinson JN, ... Weinberg RA, et al. IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization. Nature Cell Biology. 20: 1084-1097. PMID 30154549 DOI: 10.1038/S41556-018-0173-5  0.305
2018 Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, ... ... Weinberg RA, et al. An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer. Elife. 7. PMID 30059005 DOI: 10.7554/Elife.37184  0.741
2018 Fröse J, Chen MB, Hebron KE, Reinhardt F, Hajal C, Zijlstra A, Kamm RD, Weinberg RA. Epithelial-Mesenchymal Transition Induces Podocalyxin to Promote Extravasation via Ezrin Signaling. Cell Reports. 24: 962-972. PMID 30044991 DOI: 10.1016/J.Celrep.2018.06.092  0.406
2018 Zhang Y, Weinberg RA. Epithelial-to-mesenchymal transition in cancer: complexity and opportunities. Frontiers of Medicine. PMID 30043221 DOI: 10.1007/S11684-018-0656-6  0.461
2018 Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA. The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy. Science Translational Medicine. 10. PMID 29643230 DOI: 10.1126/Scitranslmed.Aan3464  0.32
2018 Brabletz T, Kalluri R, Nieto MA, Weinberg RA. EMT in cancer. Nature Reviews. Cancer. PMID 29326430 DOI: 10.1038/Nrc.2017.118  0.358
2018 Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, ... ... Weinberg RA, et al. Author response: An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer Elife. DOI: 10.7554/Elife.37184.034  0.711
2018 Guenther M, Lambert A, Chen M, Fiore C, Eaton M, Orlando D, Bierie B, Weinberg R, Fritz C, Olson E. Abstract P2-04-03: Epigenomic analysis of cancer stem cell (CSC)-enriched triple-negative breast cancer (TNBC) populations reveals gene regulatory circuitry and novel tumor cell vulnerabilities Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-04-03  0.427
2017 Guen VJ, Chavarria TE, Kröger C, Ye X, Weinberg RA, Lees JA. EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158396 DOI: 10.1073/Pnas.1711534114  0.382
2017 Rashidian M, Ingram JR, Dougan M, Dongre A, Whang KA, LeGall C, Cragnolini JJ, Bierie B, Gostissa M, Gorman J, Grotenbreg GM, Bhan A, Weinberg RA, Ploegh HL. Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells. The Journal of Experimental Medicine. PMID 28666979 DOI: 10.1084/Jem.20161950  0.301
2017 Dongre A, Rashidian M, Reinhardt F, Bagnato A, Keckesova Z, Ploegh HL, Weinberg RA. Epithelial-to-mesenchymal Transition contributes to Immunosuppression in Breast Carcinomas. Cancer Research. PMID 28428275 DOI: 10.1158/0008-5472.Can-16-3292  0.386
2017 Shibue T, Weinberg RA. EMT, CSCs, and drug resistance: the mechanistic link and clinical implications. Nature Reviews. Clinical Oncology. PMID 28397828 DOI: 10.1038/Nrclinonc.2017.44  0.329
2017 Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. PMID 28329758 DOI: 10.1038/Nature21408  0.377
2017 Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova Z, Weinberg RA. Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270621 DOI: 10.1073/Pnas.1618298114  0.441
2017 Lambert AW, Pattabiraman DR, Weinberg RA. Emerging Biological Principles of Metastasis. Cell. 168: 670-691. PMID 28187288 DOI: 10.1016/J.Cell.2016.11.037  0.329
2017 Pattabiraman DR, Weinberg RA. Targeting the Epithelial-to-Mesenchymal Transition: The Case for Differentiation-Based Therapy. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28057845 DOI: 10.1101/Sqb.2016.81.030957  0.352
2017 Li J, Choi P, Chaffer C, Labella K, Kim JW, Doench J, Dai C, Giacomelli A, Ly SH, Hwang J, Hong A, Ilic N, Gjoerup O, Meyerson M, Brooks A, ... Weinberg R, et al. Abstract A36: Genome-scale ORF screening to identify modulators of the epithelial-to-mesenchymal transition Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-A36  0.774
2017 Khodor YL, Froese J, Gertler F, Weinberg RA, Burge CB. Abstract 863: Neuronal splicing regulatory factors are upregulated in models of epithelial-mesenchymal transition Cancer Research. 77: 863-863. DOI: 10.1158/1538-7445.Am2017-863  0.436
2017 Li J, Choi P, Chaffer C, Labella K, Kim JW, Doench J, Dai C, Giacomelli A, Ly SH, Hwang J, Hong A, Ilic N, Gjoerup O, Meyerson M, Brooks A, ... Weinberg R, et al. Abstract 5020: A genome-scale ORF screen reveals an alternative splicing program that regulates mesenchymal and stem-like cell states in breast cancer Cancer Research. 77: 5020-5020. DOI: 10.1158/1538-7445.Am2017-5020  0.774
2016 Chaffer CL, San Juan BP, Lim E, Weinberg RA. EMT, cell plasticity and metastasis. Cancer Metastasis Reviews. PMID 27878502 DOI: 10.1007/S10555-016-9648-7  0.408
2016 De Cock JM, Shibue T, Dongre A, Keckesova Z, Reinhardt F, Weinberg RA. Inflammation triggers Zeb1-dependent escape from tumor latency. Cancer Research. PMID 27530323 DOI: 10.1158/0008-5472.Can-16-0608  0.407
2016 Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, ... ... Weinberg RA, et al. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells. Cancer Discovery. PMID 27072748 DOI: 10.1158/2159-8290.Cd-15-1157  0.39
2016 Pattabiraman DR, Bierie B, Kober KI, Thiru P, Krall JA, Zill C, Reinhardt F, Tam WL, Weinberg RA. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science (New York, N.Y.). 351: aad3680. PMID 26941323 DOI: 10.1126/Science.Aad3680  0.409
2016 Lu H, Tam WL, Donnenberg V, Ye X, Bhargava R, Weinberg R. Abstract B150: Juxtacrine signaling between the tumor-associated macrophages and the breast cancer stem cells contribute to the cancer stem cell niche by inducing a cytokine signaling network Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B150  0.413
2016 Castano Z, Chaffer CL, Spiegel A, Pant A, Richardson AL, Reinhardt F, Marsh T, Janssen S, Gifford AM, Weinberg RA, McAllister SS. Abstract PR13: Understanding the systemic interactions between primary tumors and disseminated tumor initiating cells Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Pr13  0.377
2016 Pattabiraman D, Shibue T, Ye X, Weinberg RA. Abstract IA26: Regulation of epithelial versus mesenchymal polarity and malignant progression Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Ia26  0.437
2015 Ye X, Weinberg RA. Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression. Trends in Cell Biology. 25: 675-86. PMID 26437589 DOI: 10.1016/J.Tcb.2015.07.012  0.354
2015 Ye X, Tam WL, Shibue T, Kaygusuz Y, Reinhardt F, Ng Eaton E, Weinberg RA. Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature. 525: 256-60. PMID 26331542 DOI: 10.1038/Nature14897  0.409
2015 Watnick RS, Rodriguez RK, Wang S, Blois AL, Rangarajan A, Ince T, Weinberg RA. Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells. Oncogene. 34: 2949-50. PMID 26020734 DOI: 10.1038/Onc.2015.183  0.389
2015 Katajisto P, Döhla J, Chaffer CL, Pentinmikko N, Marjanovic N, Iqbal S, Zoncu R, Chen W, Weinberg RA, Sabatini DM. Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. Science (New York, N.Y.). 348: 340-3. PMID 25837514 DOI: 10.1126/Science.1260384  0.354
2015 Chaffer CL, Weinberg RA. How does multistep tumorigenesis really proceed? Cancer Discovery. 5: 22-4. PMID 25583800 DOI: 10.1158/2159-8290.Cd-14-0788  0.406
2015 Watnick RS, Rodriguez RK, Wang S, Blois AL, Rangarajan A, Ince T, Weinberg RA. Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells. Oncogene. 34: 2823-35. PMID 25109329 DOI: 10.1038/Onc.2014.228  0.44
2015 Pattabiraman DR, Weinberg RA. Abstract C27: Activation of PKA induces a mesenchymal-to-epithelial transition and epigenetic reprogramming-mediated loss of tumor initiating ability Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C27  0.432
2014 Unternaehrer JJ, Zhao R, Kim K, Cesana M, Powers JT, Ratanasirintrawoot S, Onder T, Shibue T, Weinberg RA, Daley GQ. The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming. Stem Cell Reports. 3: 691-8. PMID 25316190 DOI: 10.1016/J.Stemcr.2014.09.008  0.374
2014 Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhardt F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nature Cell Biology. 16: 1105-17. PMID 25266422 DOI: 10.1038/Ncb3041  0.401
2014 Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, et al. Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 158: 1094-109. PMID 25171410 DOI: 10.1016/J.Cell.2014.07.032  0.419
2014 Pattabiraman DR, Weinberg RA. Tackling the cancer stem cells - what challenges do they pose? Nature Reviews. Drug Discovery. 13: 497-512. PMID 24981363 DOI: 10.1038/Nrd4253  0.397
2014 Weinberg RA. Abstract SY20-04: Mechanisms of malignant progression Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy20-04  0.36
2014 Hahn WC, Weinberg RA. Cancer: A Genetic Disorder The Molecular Basis of Cancer: Fourth Edition. 3-18.e1. DOI: 10.1016/B978-1-4557-4066-6.00001-9  0.356
2013 Tam WL, Weinberg RA. The epigenetics of epithelial-mesenchymal plasticity in cancer. Nature Medicine. 19: 1438-49. PMID 24202396 DOI: 10.1038/Nm.3336  0.365
2013 Shibue T, Brooks MW, Weinberg RA. An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization. Cancer Cell. 24: 481-98. PMID 24035453 DOI: 10.1016/J.Ccr.2013.08.012  0.363
2013 Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA. Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell. 24: 347-64. PMID 24029232 DOI: 10.1016/J.Ccr.2013.08.005  0.63
2013 Marjanovic ND, Weinberg RA, Chaffer CL. Poised with purpose: cell plasticity enhances tumorigenicity. Cell Cycle (Georgetown, Tex.). 12: 2713-4. PMID 23966153 DOI: 10.4161/Cc.26075  0.451
2013 Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F, D'Alessio AC, Young RA, Weinberg RA. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell. 154: 61-74. PMID 23827675 DOI: 10.1016/J.Cell.2013.06.005  0.406
2013 Marjanovic ND, Weinberg RA, Chaffer CL. Cell plasticity and heterogeneity in cancer. Clinical Chemistry. 59: 168-79. PMID 23220226 DOI: 10.1373/Clinchem.2012.184655  0.405
2013 Pfister TD, Dieckman LJ, Kinders RJ, Book A, Colantonio S, Mutreja K, Lawrence SM, Aziz A, Hiltke T, Whiteley G, Parchment RE, Tomaszewski JE, Weinberg RA, Doroshow JH. Abstract 5544: Development of recombinant transcription factor proteins and antibodies for application in clinical immunoassays. Cancer Research. 73: 5544-5544. DOI: 10.1158/1538-7445.Am2013-5544  0.355
2013 Pattabiraman DR, Reinhardt F, Bierie B, Weinberg RA. Abstract 1497: Inducing a mesenchymal-to-epithelial transition for the targeting of cancer stem cells. Cancer Research. 73: 1497-1497. DOI: 10.1158/1538-7445.Am2013-1497  0.407
2013 Weinberg RA. Abstract CN06-01: Cancer stem cells and the EMT. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-Cn06-01  0.414
2013 Scheel C, Dragoi D, Eaton EN, Hsin-Jung LS, Reinhardt F, Weinberg RA. Abstract B25: Inhibition of autocrine signaling as a strategy to target tumor-initiating breast cancer cells Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-B25  0.412
2013 Rangarajan A, Hong SJ, Gifford A, Weinberg RA. Erratum to Species- and Cell Type-Specific Requirements for Cellular Transformation [Cancer Cell 6, (2004) 171-183] Cancer Cell. 24: 394-398. DOI: 10.1016/J.Ccr.2013.08.028  0.389
2012 Li HJ, Reinhardt F, Herschman HR, Weinberg RA. Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discovery. 2: 840-55. PMID 22763855 DOI: 10.1158/2159-8290.Cd-12-0101  0.4
2012 Shibue T, Brooks MW, Inan MF, Reinhardt F, Weinberg RA. The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions. Cancer Discovery. 2: 706-21. PMID 22609699 DOI: 10.1158/2159-8290.Cd-11-0239  0.403
2012 Scheel C, Weinberg RA. Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. Seminars in Cancer Biology. 22: 396-403. PMID 22554795 DOI: 10.1016/J.Semcancer.2012.04.001  0.419
2012 Weinberg RA. Bengt Westermark and our current understanding of tumor pathogenesis. Upsala Journal of Medical Sciences. 117: 81-2. PMID 22512243 DOI: 10.3109/03009734.2012.670978  0.433
2012 Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell. 148: 1015-28. PMID 22385965 DOI: 10.1016/J.Cell.2012.02.008  0.743
2011 Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell. 147: 275-92. PMID 22000009 DOI: 10.1016/J.Cell.2011.09.024  0.413
2011 Weinberg RA. Hunting the elusive oncogene: a stroke of good luck. Nature Cell Biology. 13: 876. PMID 21808240 DOI: 10.1038/Ncb2302  0.403
2011 Scheel C, Weinberg RA. Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells? International Journal of Cancer. Journal International Du Cancer. 129: 2310-4. PMID 21792896 DOI: 10.1002/Ijc.26311  0.396
2011 Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Rubin J, Richardson AL, Weinberg RA. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 145: 926-40. PMID 21663795 DOI: 10.1016/J.Cell.2011.04.029  0.621
2011 Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proceedings of the National Academy of Sciences of the United States of America. 108: 7950-5. PMID 21498687 DOI: 10.1073/Pnas.1102454108  0.395
2011 Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science (New York, N.Y.). 331: 1559-64. PMID 21436443 DOI: 10.1126/Science.1203543  0.357
2011 Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 144: 646-74. PMID 21376230 DOI: 10.1016/J.Cell.2011.02.013  0.402
2011 Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirström K, Magnusson K, Ebert BL, Pontén F, Weinberg RA, McAllister SS. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. The Journal of Clinical Investigation. 121: 784-99. PMID 21266779 DOI: 10.1172/Jci43757  0.389
2011 Shibue T, Weinberg RA. Metastatic colonization: settlement, adaptation and propagation of tumor cells in a foreign tissue environment. Seminars in Cancer Biology. 21: 99-106. PMID 21145969 DOI: 10.1016/J.Semcancer.2010.12.003  0.356
2011 Rai P, Young JJ, Burton DG, Giribaldi MG, Onder TT, Weinberg RA. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence. Oncogene. 30: 1489-96. PMID 21076467 DOI: 10.1038/Onc.2010.520  0.359
2011 Scheel C, NgEaton E, Li SH, Chaffer CL, Reinhardt F, Kah K, Bell G, Guo W, Rubin J, Richardson A, Weinberg RA. Abstract LB-108: Formation and maintenance of mesenchymal and stem-cell states in the breast by paracrine and autocrine signals Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-108  0.638
2010 Kojima Y, Acar A, Eaton EN, Mellody KT, Scheel C, Ben-Porath I, Onder TT, Wang ZC, Richardson AL, Weinberg RA, Orimo A. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 107: 20009-14. PMID 21041659 DOI: 10.1073/Pnas.1013805107  0.372
2010 Roussos ET, Keckesova Z, Haley JD, Epstein DM, Weinberg RA, Condeelis JS. AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment. Cancer Research. 70: 7360-4. PMID 20823151 DOI: 10.1158/0008-5472.Can-10-1208  0.374
2010 Chaffer CL, Weinberg RA. Cancer cell of origin: spotlight on luminal progenitors. Cell Stem Cell. 7: 271-2. PMID 20804960 DOI: 10.1016/J.Stem.2010.08.008  0.375
2010 Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 15449-54. PMID 20713713 DOI: 10.1073/Pnas.1004900107  0.632
2010 McAllister SS, Weinberg RA. Tumor-host interactions: a far-reaching relationship. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4022-8. PMID 20644094 DOI: 10.1200/Jco.2010.28.4257  0.348
2010 Weinberg R, Fisher DE, Rich J. Dynamic and transient cancer stem cells nurture melanoma. Nature Medicine. 16: 758. PMID 20613753 DOI: 10.1038/Nm0710-758  0.339
2010 Blick T, Hugo H, Widodo E, Waltham M, Pinto C, Mani SA, Weinberg RA, Neve RM, Lenburg ME, Thompson EW. Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. Journal of Mammary Gland Biology and Neoplasia. 15: 235-52. PMID 20521089 DOI: 10.1007/S10911-010-9175-Z  0.628
2010 Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, Teruya-Feldstein J, Reinhardt F, Onder TT, Valastyan S, Westermann F, Speleman F, Vandesompele J, Weinberg RA. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nature Cell Biology. 12: 247-56. PMID 20173740 DOI: 10.1038/Ncb2024  0.306
2010 Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, et al. Erratum: Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudinlow and metaplastic breast cancer subtypes (Proceedings of the National Academy of Sciences of the United States of America (2010) 107:35 (15449-15454)) Proceedings of the National Academy of Sciences of the United States of America. 107. DOI: 10.1073/Pnas.1015095107  0.584
2009 Valastyan S, Weinberg RA. Assaying microRNA loss-of-function phenotypes in mammalian cells: emerging tools and their potential therapeutic utility. Rna Biology. 6: 541-5. PMID 19901530 DOI: 10.4161/Rna.6.5.10081  0.351
2009 Valastyan S, Weinberg RA. MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis. Cell Cycle (Georgetown, Tex.). 8: 3506-12. PMID 19838065 DOI: 10.4161/Cc.8.21.9802  0.32
2009 Gupta PB, Chaffer CL, Weinberg RA. Cancer stem cells: mirage or reality? Nature Medicine. 15: 1010-2. PMID 19734877 DOI: 10.1038/Nm0909-1010  0.375
2009 Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell. 138: 645-59. PMID 19682730 DOI: 10.1016/J.Cell.2009.06.034  0.384
2009 Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szász AM, Wang ZC, Brock JE, Richardson AL, Weinberg RA. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 137: 1032-46. PMID 19524507 DOI: 10.1016/J.Cell.2009.03.047  0.303
2009 Shibue T, Weinberg RA. Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proceedings of the National Academy of Sciences of the United States of America. 106: 10290-5. PMID 19502425 DOI: 10.1073/Pnas.0904227106  0.385
2009 Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. The Journal of Clinical Investigation. 119: 1420-8. PMID 19487818 DOI: 10.1172/Jci39104  0.339
2009 Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nature Reviews. Cancer. 9: 265-73. PMID 19262571 DOI: 10.1038/Nrc2620  0.366
2009 Rai P, Onder TT, Young JJ, McFaline JL, Pang B, Dedon PC, Weinberg RA. Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 106: 169-74. PMID 19118192 DOI: 10.1073/Pnas.0809834106  0.345
2009 Weinberg R. Breast Cancer Stem Cells and the Epithelial-Mesenchymal Transition. Cancer Research. 69. DOI: 10.1158/0008-5472.Sabcs-09-A1-1  0.439
2009 Weinberg RA. Abstract IA-21: Malignant progression and the stem‐cell state Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-Ia-21  0.461
2009 McAllister SS, Scheel C, Nilsson B, Gifford AM, Reinhardt F, Bray M, Carpenter AE, Ebert BL, Weinberg RA. Abstract C75: Granulin‐expressing bone marrow cells promote the outgrowth of indolent tumors Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-C75  0.403
2008 Weinberg RA. Leaving home early: reexamination of the canonical models of tumor progression. Cancer Cell. 14: 283-4. PMID 18835030 DOI: 10.1016/J.Ccr.2008.09.009  0.306
2008 Weinberg RA. Twisted epithelial-mesenchymal transition blocks senescence. Nature Cell Biology. 10: 1021-3. PMID 18758491 DOI: 10.1038/Ncb0908-1021  0.359
2008 Ma L, Weinberg RA. Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends in Genetics : Tig. 24: 448-56. PMID 18674843 DOI: 10.1016/J.Tig.2008.06.004  0.347
2008 Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 134: 62-73. PMID 18614011 DOI: 10.1016/J.Cell.2008.06.006  0.629
2008 McAllister SS, Gifford AM, Greiner AL, Kelleher SP, Saelzler MP, Ince TA, Reinhardt F, Harris LN, Hylander BL, Repasky EA, Weinberg RA. Systemic endocrine instigation of indolent tumor growth requires osteopontin. Cell. 133: 994-1005. PMID 18555776 DOI: 10.1016/J.Cell.2008.04.045  0.323
2008 Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Developmental Cell. 14: 818-29. PMID 18539112 DOI: 10.1016/J.Devcel.2008.05.009  0.377
2008 Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 133: 704-15. PMID 18485877 DOI: 10.1016/J.Cell.2008.03.027  0.745
2008 Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Research. 68: 3645-54. PMID 18483246 DOI: 10.1158/0008-5472.Can-07-2938  0.594
2008 Weinberg RA. Mechanisms of malignant progression. Carcinogenesis. 29: 1092-5. PMID 18453542 DOI: 10.1093/Carcin/Bgn104  0.322
2008 Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nature Genetics. 40: 499-507. PMID 18443585 DOI: 10.1038/Ng.127  0.422
2008 Weinberg RA. Coevolution in the tumor microenvironment. Nature Genetics. 40: 494-5. PMID 18443582 DOI: 10.1038/Ng0508-494  0.362
2007 Scheel C, Onder T, Karnoub A, Weinberg RA. Adaptation versus selection: the origins of metastatic behavior. Cancer Research. 67: 11476-9; discussion . PMID 18089773 DOI: 10.1158/0008-5472.Can-07-1653  0.311
2007 Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 449: 557-63. PMID 17914389 DOI: 10.1038/Nature06188  0.411
2007 Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature. 449: 682-8. PMID 17898713 DOI: 10.1038/Nature06174  0.323
2007 Liao MJ, Zhang CC, Zhou B, Zimonjic DB, Mani SA, Kaba M, Gifford A, Reinhardt F, Popescu NC, Guo W, Eaton EN, Lodish HF, Weinberg RA. Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Research. 67: 8131-8. PMID 17804725 DOI: 10.1158/0008-5472.Can-06-4493  0.74
2007 Ince TA, Richardson AL, Bell GW, Saitoh M, Godar S, Karnoub AE, Iglehart JD, Weinberg RA. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 12: 160-70. PMID 17692807 DOI: 10.1016/J.Ccr.2007.06.013  0.421
2007 Mani SA, Yang J, Brooks M, Schwaninger G, Zhou A, Miura N, Kutok JL, Hartwell K, Richardson AL, Weinberg RA. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proceedings of the National Academy of Sciences of the United States of America. 104: 10069-74. PMID 17537911 DOI: 10.1073/Pnas.0703900104  0.662
2007 Gupta PB, Proia D, Cingoz O, Weremowicz J, Naber SP, Weinberg RA, Kuperwasser C. Systemic stromal effects of estrogen promote the growth of estrogen receptor-negative cancers. Cancer Research. 67: 2062-71. PMID 17332335 DOI: 10.1158/0008-5472.Can-06-3895  0.347
2006 Karnoub AE, Weinberg RA. Chemokine networks and breast cancer metastasis. Breast Disease. 26: 75-85. PMID 17473367 DOI: 10.3233/Bd-2007-26107  0.371
2006 Weinberg R, Mihich E. Eighteenth annual pezcoller symposium: tumor microenvironment and heterotypic interactions. Cancer Research. 66: 11550-3. PMID 17158190 DOI: 10.1158/0008-5472.Can-06-3149  0.346
2006 Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA. The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 18969-74. PMID 17142318 DOI: 10.1073/Pnas.0608636103  0.432
2006 Orimo A, Weinberg RA. Stromal fibroblasts in cancer: a novel tumor-promoting cell type. Cell Cycle (Georgetown, Tex.). 5: 1597-601. PMID 16880743 DOI: 10.4161/Cc.5.15.3112  0.413
2006 Stewart SA, Weinberg RA. Telomeres: cancer to human aging. Annual Review of Cell and Developmental Biology. 22: 531-57. PMID 16824017 DOI: 10.1146/Annurev.Cellbio.22.010305.104518  0.401
2006 Yang J, Mani SA, Weinberg RA. Exploring a new twist on tumor metastasis. Cancer Research. 66: 4549-52. PMID 16651402 DOI: 10.1158/0008-5472.Can-05-3850  0.618
2005 Gupta PB, Mani S, Yang J, Hartwell K, Weinberg RA. The evolving portrait of cancer metastasis. Cold Spring Harbor Symposia On Quantitative Biology. 70: 291-7. PMID 16869765 DOI: 10.1101/Sqb.2005.70.033  0.62
2005 Gupta PB, Kuperwasser C, Brunet JP, Ramaswamy S, Kuo WL, Gray JW, Naber SP, Weinberg RA. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nature Genetics. 37: 1047-54. PMID 16142232 DOI: 10.1038/Ng1634  0.4
2005 Kuperwasser C, Dessain S, Bierbaum BE, Garnet D, Sperandio K, Gauvin GP, Naber SP, Weinberg RA, Rosenblatt M. A mouse model of human breast cancer metastasis to human bone. Cancer Research. 65: 6130-8. PMID 16024614 DOI: 10.1158/0008-5472.Can-04-1408  0.323
2005 Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 121: 335-48. PMID 15882617 DOI: 10.1016/J.Cell.2005.02.034  0.383
2005 Ben-Porath I, Weinberg RA. The signals and pathways activating cellular senescence. The International Journal of Biochemistry & Cell Biology. 37: 961-76. PMID 15743671 DOI: 10.1016/J.Biocel.2004.10.013  0.333
2004 Rangarajan A, Hong SJ, Gifford A, Weinberg RA. Species- and cell type-specific requirements for cellular transformation. Cancer Cell. 6: 171-83. PMID 15324700 DOI: 10.1016/J.Ccr.2004.07.009  0.415
2004 Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell. 117: 927-39. PMID 15210113 DOI: 10.1016/J.Cell.2004.06.006  0.643
2004 Kuperwasser C, Chavarria T, Wu M, Magrane G, Gray JW, Carey L, Richardson A, Weinberg RA. Reconstruction of functionally normal and malignant human breast tissues in mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 4966-71. PMID 15051869 DOI: 10.1073/Pnas.0401064101  0.354
2004 Ben-Porath I, Weinberg RA. When cells get stressed: an integrative view of cellular senescence. The Journal of Clinical Investigation. 113: 8-13. PMID 14702100 DOI: 10.1172/Jci20663  0.368
2003 Rangarajan A, Weinberg RA. Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice. Nature Reviews. Cancer. 3: 952-9. PMID 14737125 DOI: 10.1038/Nrc1235  0.304
2003 Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA, Hahn WC. Telomerase maintains telomere structure in normal human cells. Cell. 114: 241-53. PMID 12887925 DOI: 10.1016/S0092-8674(03)00550-6  0.559
2003 Stenvers KL, Tursky ML, Harder KW, Kountouri N, Amatayakul-Chantler S, Grail D, Small C, Weinberg RA, Sizeland AM, Zhu HJ. Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos. Molecular and Cellular Biology. 23: 4371-85. PMID 12773577 DOI: 10.1128/Mcb.23.12.4371-4385.2003  0.311
2003 Watnick RS, Cheng YN, Rangarajan A, Ince TA, Weinberg RA. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell. 3: 219-31. PMID 12676581 DOI: 10.1016/S1535-6108(03)00030-8  0.383
2003 Stewart SA, Ben-Porath I, Carey VJ, O'Connor BF, Hahn WC, Weinberg RA. Erosion of the telomeric single-strand overhang at replicative senescence. Nature Genetics. 33: 492-6. PMID 12652299 DOI: 10.1038/Ng1127  0.525
2003 Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. Lentivirus-delivered stable gene silencing by RNAi in primary cells. Rna (New York, N.Y.). 9: 493-501. PMID 12649500 DOI: 10.1261/Rna.2192803  0.538
2002 Jacks T, Weinberg RA. Taking the study of cancer cell survival to a new dimension. Cell. 111: 923-5. PMID 12507419 DOI: 10.1016/S0092-8674(02)01229-1  0.659
2002 Brisken C, Ayyannan A, Nguyen C, Heineman A, Reinhardt F, Tan J, Dey SK, Dotto GP, Weinberg RA, Jan T. IGF-2 is a mediator of prolactin-induced morphogenesis in the breast. Developmental Cell. 3: 877-87. PMID 12479812 DOI: 10.1016/S1534-5807(02)00365-9  0.312
2002 Hahn WC, Weinberg RA. Rules for making human tumor cells New England Journal of Medicine. 347: 1593-1603. PMID 12432047 DOI: 10.1056/Nejmra021902  0.561
2002 Brisken C, Socolovsky M, Lodish HF, Weinberg R. The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium Proceedings of the National Academy of Sciences of the United States of America. 99: 14241-14245. PMID 12381781 DOI: 10.1073/Pnas.222549599  0.321
2002 Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 99: 12606-11. PMID 12193655 DOI: 10.1073/Pnas.182407599  0.577
2002 Ince TA, Weinberg RA. Functional genomics and the breast cancer problem Cancer Cell. 1: 15-17. PMID 12086883 DOI: 10.1016/S1535-6108(02)00023-5  0.316
2002 Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks MW, Fleming MD, Olsen JC, Miller SW, Weinberg RA, Hahn WC. Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene. 21: 4577-86. PMID 12085236 DOI: 10.1038/Sj.Onc.1205550  0.58
2002 Hahn WC, Weinberg RA. Modelling the molecular circuitry of cancer Nature Reviews Cancer. 2: 331-341. PMID 12044009 DOI: 10.1038/Nrc795  0.522
2002 Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, DeCaprio JA, Weinberg RA. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Molecular and Cellular Biology. 22: 2111-23. PMID 11884599 DOI: 10.1128/Mcb.22.7.2111-2123.2002  0.602
2002 Bernards R, Weinberg RA. Metastasis: objections to the same-gene model Nature. 419: 560-560. DOI: 10.1038/419560B  0.376
2001 Vaziri H, Dessain SK, Eaton EN, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase Cell. 107: 149-159. PMID 11672523 DOI: 10.1016/S0092-8674(01)00527-X  0.344
2001 Liu X, Sun Y, Weinberg RA, Lodish HF. Ski/Sno and TGF-β signaling Cytokine and Growth Factor Reviews. 12: 1-8. PMID 11312113 DOI: 10.1016/S1359-6101(00)00031-9  0.309
2001 Schratt G, Weinhold B, Lundberg AS, Schuck S, Berger J, Schwarz H, Weinberg RA, Rüther U, Nordheim A. Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cells. Molecular and Cellular Biology. 21: 2933-43. PMID 11283270 DOI: 10.1128/Mcb.21.8.2933-2943.2001  0.415
2001 Elenbaas B, Weinberg RA. Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation Experimental Cell Research. 264: 169-184. PMID 11237532 DOI: 10.1006/Excr.2000.5133  0.404
2001 Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, Popescu NC, Hahn WC, Weinberg RA. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes & Development. 15: 50-65. PMID 11156605 DOI: 10.1101/gad.828901  0.555
2001 Hahn W, Elenbaas B, Stewart S, Watnick R, Yang J, Mani S, Weinberg R. Rules governing the creation of human tumor cells European Journal of Cancer. 37: S369. DOI: 10.1016/S0959-8049(01)81861-X  0.677
2001 Weinberg RA. Cellular Brake Pad Inspection Cell. 105: 318-319. DOI: 10.1016/S0092-8674(01)00350-6  0.426
2000 Stewart SA, Weinberg RA. Telomerase and human tumorigenesis Seminars in Cancer Biology. 10: 399-406. PMID 11170862 DOI: 10.1006/Scbi.2000.0339  0.426
2000 Liu X, Sun Y, Ehrlich M, Lu T, Kloog Y, Weinberg RA, Lodish HF, Henis YI. Disruption of TGF-β growth inhibition by oncogenic ras is linked to p27(kip1) mislocalization Oncogene. 19: 5926-5935. PMID 11127824 DOI: 10.1038/Sj.Onc.1203991  0.318
2000 Lundberg AS, Hahn WC, Gupta P, Weinberg RA. Genes involved in senescence and immortalization. Current Opinion in Cell Biology. 12: 705-9. PMID 11063935 DOI: 10.1016/S0955-0674(00)00155-1  0.534
2000 Liu X, Constantinescu SN, Sun Y, Bogan JS, Hirsch D, Weinberg RA, Lodish HF. Generation of mammalian cells stably expressing multiple genes at predetermined levels Analytical Biochemistry. 280: 20-28. PMID 10805516 DOI: 10.1006/Abio.2000.4478  0.358
2000 Solvason N, Wu WW, Parry D, Mahony D, Lam EW-, Glassford J, Klaus GGB, Sicinski P, Weinberg R, Liu YJ, Howard M, Lees E. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development International Immunology. 12: 631-638. PMID 10784609 DOI: 10.1093/Intimm/12.5.631  0.302
2000 Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA. Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes & Development. 14: 650-4. PMID 10733525 DOI: 10.1101/Gad.14.6.650  0.301
2000 Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Molecular and Cellular Biology. 20: 1436-47. PMID 10648628 DOI: 10.1128/Mcb.20.4.1436-1447.2000  0.571
1999 Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA. Inhibition of telomerase limits the growth of human cancer cells. Nature Medicine. 5: 1164-70. PMID 10502820 DOI: 10.1038/13495  0.653
1999 Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA. Creation of human tumour cells with defined genetic elements. Nature. 400: 464-8. PMID 10440377 DOI: 10.1038/22780  0.73
1999 Geng Y, Whoriskey W, Park MY, Bronson RT, Medema RH, Li T, Weinberg RA, Sicinski P. Rescue of cyclin D1 deficiency by knockin cyclin E Cell. 97: 767-777. PMID 10380928 DOI: 10.1016/S0092-8674(00)80788-6  0.515
1999 Lees JA, Weinberg RA. Tossing monkey wrenches into the clock: new ways of treating cancer. Proceedings of the National Academy of Sciences of the United States of America. 96: 4221-3. PMID 10200241 DOI: 10.1073/Pnas.96.8.4221  0.349
1998 Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proceedings of the National Academy of Sciences of the United States of America. 95: 14723-8. PMID 9843956 DOI: 10.1073/Pnas.95.25.14723  0.712
1998 Weinberg RA. Bumps on the road to immortality Nature. 396: 23-24. PMID 9817198 DOI: 10.1038/23825  0.362
1998 Robles AI, Rodriguez-Puebla ML, Glick AB, Trempus C, Hansen L, Sicinski P, Tennant RW, Weinberg RA, Yuspa SH, Conti CJ. Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo Genes and Development. 12: 2469-2474. PMID 9716400 DOI: 10.1101/Gad.12.16.2469  0.338
1998 Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA, Gerald WL. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nature Genetics. 19: 182-6. PMID 9620778 DOI: 10.1038/554  0.713
1998 Jacks T, Weinberg RA. The expanding role of cell cycle regulators Science. 280: 1035-1036. PMID 9616080 DOI: 10.1126/Science.280.5366.1035  0.645
1998 Brisken C, Park S, Vass T, Lydon JP, O'Malley BW, Weinberg RA. A paracrine role for the epithelial progesterone receptor in mammary gland development Proceedings of the National Academy of Sciences of the United States of America. 95: 5076-5081. PMID 9560231 DOI: 10.1073/Pnas.95.9.5076  0.333
1998 Hatakeyama M, Weinberg RA. The role of RB in cell cycle control. Progress in Cell Cycle Research. 1: 9-19. PMID 9552350 DOI: 10.1007/978-1-4615-1809-9_2  0.345
1998 Counter CM, Meyerson M, Eaton EN, Ellisen LW, Caddle SD, Haber DA, Weinberg RA. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene. 16: 1217-22. PMID 9528864 DOI: 10.1038/Sj.Onc.1201882  0.719
1998 Orr-Weaver TL, Weinberg RA. A checkpoint on the road to cancer. Nature. 392: 223-4. PMID 9521314 DOI: 10.1038/32520  0.368
1997 Planas-Silva MD, Weinberg RA. The restriction point and control of cell proliferation Current Opinion in Cell Biology. 9: 768-772. PMID 9425340 DOI: 10.1016/S0955-0674(97)80076-2  0.335
1997 Liu X, Sun Y, Constantinescu SN, Karam E, Weinberg RA, Lodish HF. Transforming growth factorβ-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 94: 10669-10674. PMID 9380693 DOI: 10.1073/Pnas.94.20.10669  0.309
1997 Fazeli A, Steen RG, Dickinson SL, Bautista D, Dietrich WF, Bronson RT, Bresalier RS, Lander ES, Costa J, Weinberg RA. Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas Proceedings of the National Academy of Sciences of the United States of America. 94: 10199-10204. PMID 9294187 DOI: 10.1073/Pnas.94.19.10199  0.354
1997 Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 90: 785-95. PMID 9288757 DOI: 10.1016/S0092-8674(00)80538-3  0.722
1997 Counter CM, Meyerson M, Eaton EN, Weinberg RA. The catalytic subunit of yeast telomerase. Proceedings of the National Academy of Sciences of the United States of America. 94: 9202-7. PMID 9256460 DOI: 10.1073/Pnas.94.17.9202  0.653
1997 Steiner P, Barnes DM, Harris WH, Weinberg RA. Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer Nature Genetics. 16: 332-333. PMID 9241265 DOI: 10.1038/Ng0897-332  0.317
1997 Planas-Silva MD, Weinberg RA. Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution Molecular and Cellular Biology. 17: 4059-4069. PMID 9199341 DOI: 10.1128/Mcb.17.7.4059  0.364
1997 Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature. 386: 796-804. PMID 9126737 DOI: 10.1038/386796A0  0.307
1997 Weinberg RA. The cat and mouse games that genes, viruses, and cells play. Cell. 88: 573-5. PMID 9054495 DOI: 10.1016/S0092-8674(00)81897-8  0.311
1997 Herrera RE, Mäkelä TP, Weinberg RA. TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein. Molecular Biology of the Cell. 7: 1335-42. PMID 8885230 DOI: 10.1091/Mbc.7.9.1335  0.3
1996 Sicinski P, Donaher JL, Geng Y, Parker SB, Gardner H, Park MY, Robker RL, Richards JS, McGinnis LK, Biggers JD, Eppig JJ, Bronson RT, Elledge SJ, Weinberg RA. Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis. Nature. 384: 470-4. PMID 8945475 DOI: 10.1038/384470A0  0.342
1996 Herrera RE, Chen F, Weinberg RA. Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 93: 11510-5. PMID 8876166 DOI: 10.1073/Pnas.93.21.11510  0.305
1996 Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes & Development. 10: 1633-44. PMID 8682294 DOI: 10.1101/Gad.10.13.1633  0.774
1996 Wang Z, Sicinski P, Weinberg RA, Zhang Y, Ravid K. Characterization of the mouse cyclin D3 gene: Exon/intron organization and promoter activity Genomics. 35: 156-163. PMID 8661116 DOI: 10.1006/Geno.1996.0334  0.357
1996 Weinberg RA. E2F and cell proliferation: a world turned upside down. Cell. 85: 457-9. PMID 8653779 DOI: 10.1016/S0092-8674(00)81244-1  0.407
1996 Jacks T, Weinberg RA. Cell-cycle control and its watchman. Nature. 381: 643-4. PMID 8649505 DOI: 10.1038/381643A0  0.633
1996 Herrera RE, Sah VP, Williams BO, Mäkelä TP, Weinberg RA, Jacks T. Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts Molecular and Cellular Biology. 16: 2402-2407. PMID 8628308 DOI: 10.1128/Mcb.16.5.2402  0.729
1995 Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, Chen A, Weinberg RA. E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 92: 2403-7. PMID 7892279 DOI: 10.1073/Pnas.92.6.2403  0.348
1995 Serizawa H, Mäkelä TP, Conaway JW, Conaway RC, Weinberg RA, Young RA. Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature. 374: 280-2. PMID 7885450 DOI: 10.1038/374280A0  0.307
1995 Weinberg RA. The retinoblastoma protein and cell cycle control. Cell. 81: 323-30. PMID 7736585 DOI: 10.1016/0092-8674(95)90385-2  0.32
1995 Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, Haslam SZ, Bronson RT, Elledge SJ, Weinberg RA. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell. 82: 621-30. PMID 7664341 DOI: 10.1016/0092-8674(95)90034-9  0.309
1995 Weinberg RA. The molecular basis of oncogenes and tumor suppressor genes. Annals of the New York Academy of Sciences. 758: 331-8. PMID 7625701 DOI: 10.1111/J.1749-6632.1995.Tb24838.X  0.31
1995 Medema RH, Herrera RE, Lam F, Weinberg RA. Growth suppression by p16ink4 requires functional retinoblastoma protein. Proceedings of the National Academy of Sciences of the United States of America. 92: 6289-93. PMID 7603984 DOI: 10.1073/Pnas.92.14.6289  0.601
1994 Hinds PW, Dowdy SF, Eaton EN, Arnold A, Weinberg RA. Function of a human cyclin gene as an oncogene Proceedings of the National Academy of Sciences of the United States of America. 91: 709-713. PMID 8290586 DOI: 10.1073/Pnas.91.2.709  0.423
1994 Williams BO, Schmitt EM, Remington L, Bronson RT, Albert DM, Weinberg RA, Jacks T. Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences Embo Journal. 13: 4251-4259. PMID 7925270 DOI: 10.1002/J.1460-2075.1994.Tb06745.X  0.736
1994 Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT, Weinberg RA. Tumor spectrum analysis in p53-mutant mice Current Biology. 4: 1-7. PMID 7922305 DOI: 10.1016/S0960-9822(00)00002-6  0.719
1994 Jacks T, Shih TS, Schmitt EM, Bronson RT, Bernards A, Weinberg RA. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 Nature Genetics. 7: 353-361. PMID 7920653 DOI: 10.1038/ng0794-353  0.551
1994 Weinberg RA. Oncogenes and tumor suppressor genes Ca: a Cancer Journal For Clinicians. 44: 160-170. PMID 7621068 DOI: 10.3322/Canjclin.44.3.160  0.329
1994 Hatakeyama M, Herrera RA, Makela T, Dowdy SF, Jacks T, Weinberg RA. The cancer cell and the cell cycle clock. Cold Spring Harbor Symposia On Quantitative Biology. 59: 1-10. PMID 7587058 DOI: 10.1101/Sqb.1994.059.01.003  0.654
1993 Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 363: 45-51. PMID 8479536 DOI: 10.1038/363045A0  0.623
1993 Egan SE, Weinberg RA. The pathway to signal achievement Nature. 365: 781-783. PMID 8413661 DOI: 10.1038/365781A0  0.595
1993 Cobrinik D, Whyte P, Peeper DS, Jacks T, Weinberg RA. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes & Development. 7: 2392-404. PMID 8253385 DOI: 10.1101/Gad.7.12A.2392  0.624
1993 Simon M, Dodson G, Rubin G, Olivier J, Egan S, Giddings B, Brooks M, Buday L, Sizeland A, Weinberg R, Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D, et al. Tyrosine kinases to Ras Trends in Cell Biology. 3: 228. DOI: 10.1016/0962-8924(93)90117-J  0.701
1993 Albright C, Giddings B, Liu J, Vito M, Weinberg R. Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase. The Embo Journal. 12: 339-347. DOI: 10.1002/J.1460-2075.1993.Tb05662.X  0.303
1992 Massagué J, Weinberg RA. Negative regulators of growth. Current Opinion in Genetics & Development. 2: 28-32. PMID 1633423 DOI: 10.1016/S0959-437X(05)80317-X  0.344
1992 Settleman J, Narasimhan V, Foster LC, Weinberg RA. Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus Cell. 69: 539-549. PMID 1581965 DOI: 10.1016/0092-8674(92)90454-K  0.327
1992 Settleman J, Albright CF, Foster LC, Weinberg RA. Association between GTPase activators for Rho and Ras families Nature. 359: 153-154. PMID 1522900 DOI: 10.1038/359153A0  0.633
1992 Weinberg RA. The integration of molecular genetics into cancer management. Cancer. 70: 1653-8. PMID 1516021 DOI: 10.1002/1097-0142(19920915)70:4+<1653::Aid-Cncr2820701603>3.0.Co;2-1  0.413
1992 Cobrinik D, Dowdy SF, Hinds PW, Mittnacht S, Weinberg RA. The retinoblastoma protein and the regulation of cell cycling Trends in Biochemical Sciences. 17: 312-315. PMID 1412705 DOI: 10.1016/0968-0004(92)90443-D  0.337
1992 Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA. Effects of an Rb mutation in the mouse Nature. 359: 295-300. PMID 1406933 DOI: 10.1038/359295A0  0.622
1992 Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins Cell. 70: 993-1006. PMID 1388095 DOI: 10.1016/0092-8674(92)90249-C  0.39
1991 Mittnacht S, Weinberg RA. G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment. Cell. 65: 381-93. PMID 2018973 DOI: 10.1016/0092-8674(91)90456-9  0.305
1991 Templeton DJ, Park SH, Lanier L, Weinberg RA. Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering. Proceedings of the National Academy of Sciences of the United States of America. 88: 3033-7. PMID 1826560 DOI: 10.1073/Pnas.88.8.3033  0.343
1991 Mittnacht S, Hinds PW, Dowdy SF, Weinberg RA. Modulation of retinoblastoma protein activity during the cell cycle Cold Spring Harbor Symposia On Quantitative Biology. 56: 197-209. PMID 1819486 DOI: 10.1101/Sqb.1991.056.01.025  0.323
1991 Weinberg RA. Tumor suppressor genes. Science (New York, N.Y.). 254: 1138-46. PMID 1659741 DOI: 10.1016/0959-437X(94)90102-3  0.341
1991 Wang XF, Lin HY, Ng-Eaton E, Downward J, Lodish HF, Weinberg RA. Expression cloning and characterization of the TGF-beta type III receptor. Cell. 67: 797-805. PMID 1657407 DOI: 10.1016/0092-8674(91)90074-9  0.481
1990 Weinberg RA. The genetic bases of cancer. Lucy Wortham James lecture. Archives of Surgery (Chicago, Ill. : 1960). 125: 257-60. PMID 2405814 DOI: 10.1001/Archsurg.1990.01410140135022  0.318
1990 Weinberg RA. The retinoblastoma gene and cell growth control. Trends in Biochemical Sciences. 15: 199-202. PMID 2193439 DOI: 10.1016/0968-0004(90)90162-5  0.316
1990 Horowitz JM, Park SH, Bogenmann E, Cheng JC, Yandell DW, Kaye FJ, Minna JD, Dryja TP, Weinberg RA. Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells Proceedings of the National Academy of Sciences of the United States of America. 87: 2775-2779. PMID 2181449 DOI: 10.1073/Pnas.87.7.2775  0.395
1990 Downward J, Riehl R, Wu L, Weinberg RA. Identification of a nucleotide exchange-promoting activity for p21ras. Proceedings of the National Academy of Sciences of the United States of America. 87: 5998-6002. PMID 2116014 DOI: 10.1073/Pnas.87.15.5998  0.509
1989 Horowitz JM, Yandell DW, Park SH, Canning S, Whyte P, Buchkovich K, Harlow E, Weinberg RA, Dryja TP. Point mutational inactivation of the retinoblastoma antioncogene. Science (New York, N.Y.). 243: 937-40. PMID 2521957 DOI: 10.1126/Science.2521957  0.303
1989 Avraham H, Weinberg RA. Characterization and expression of the human rhoH12 gene product. Molecular and Cellular Biology. 9: 2058-66. PMID 2501657 DOI: 10.1128/Mcb.9.5.2058  0.366
1989 de Gunzburg J, Riehl R, Weinberg RA. Identification of a protein associated with p21ras by chemical crosslinking. Proceedings of the National Academy of Sciences of the United States of America. 86: 4007-11. PMID 2498879 DOI: 10.1073/Pnas.86.11.4007  0.356
1989 Yarden Y, Weinberg RA. Experimental approaches to hypothetical hormones: detection of a candidate ligand of the neu protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 86: 3179-83. PMID 2470093 DOI: 10.1073/Pnas.86.9.3179  0.515
1989 Rogelj S, Weinberg RA, Fanning P, Klagsbrun M. Characterization of tumors produced by signal peptide-basic fibroblast growth factor-transformed cells Journal of Cellular Biochemistry. 39: 13-23. PMID 2469690 DOI: 10.1002/Jcb.240390103  0.359
1988 Rogelj S, Weinberg RA, Fanning P, Klagsbrun M. Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature. 331: 173-5. PMID 3340164 DOI: 10.1038/331173A0  0.36
1988 Friend SH, Dryja TP, Weinberg RA. Oncogenes and tumor-suppressing genes. The New England Journal of Medicine. 318: 618-22. PMID 3278233 DOI: 10.1056/Nejm198803103181007  0.354
1988 Downward J, Weinberg RA. Influence of p21ras on phosphatidylinositol turnover. Cold Spring Harbor Symposia On Quantitative Biology. 53: 883-92. PMID 2908199 DOI: 10.1101/Sqb.1988.053.01.101  0.442
1988 Horowitz JM, Friend SH, Weinberg RA, Whyte P, Buchkovich K, Harlow E. Anti-oncogenes and the negative regulation of cell growth. Cold Spring Harbor Symposia On Quantitative Biology. 53: 843-7. PMID 2908198 DOI: 10.1101/Sqb.1988.053.01.096  0.364
1988 Bargmann CI, Weinberg RA. Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion. The Embo Journal. 7: 2043-52. PMID 2901345  0.505
1988 Downward J, de Gunzburg J, Riehl R, Weinberg RA. p21ras-induced responsiveness of phosphatidylinositol turnover to bradykinin is a receptor number effect. Proceedings of the National Academy of Sciences of the United States of America. 85: 5774-8. PMID 2901087 DOI: 10.1073/Pnas.85.16.5774  0.539
1988 Bargmann CI, Weinberg RA. Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene. Proceedings of the National Academy of Sciences of the United States of America. 85: 5394-8. PMID 2899890 DOI: 10.1073/Pnas.85.15.5394  0.569
1988 Kimchi A, Wang XF, Weinberg RA, Cheifetz S, Massagué J. Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells Science. 240: 196-199. PMID 2895499 DOI: 10.1126/Science.2895499  0.365
1988 Dotto GP, Weinberg RA, Ariza A. Malignant transformation of mouse primary keratinocytes by Harvey sarcoma virus and its modulation by surrounding normal cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 6389-93. PMID 2457913 DOI: 10.1073/Pnas.85.17.6389  0.4
1987 Stern DF, Hare DL, Cecchini MA, Weinberg RA. Construction of a novel oncogene based on synthetic sequences encoding epidermal growth factor. Science (New York, N.Y.). 235: 321-4. PMID 3492043 DOI: 10.1126/science.3492043  0.535
1987 Friend SH, Horowitz JM, Gerber MR, Wang XF, Bogenmann E, Li FP, Weinberg RA. Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein Proceedings of the National Academy of Sciences of the United States of America. 84: 9059-9063. PMID 3480530 DOI: 10.1073/Pnas.84.24.9059  0.324
1987 Bernards R, Destree A, McKenzie S, Gordon E, Weinberg RA, Panicali D. Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector. Proceedings of the National Academy of Sciences of the United States of America. 84: 6854-8. PMID 3477812 DOI: 10.1073/Pnas.84.19.6854  0.354
1987 Drebin JA, Link VC, Weinberg RA, Greene MI. Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 83: 9129-33. PMID 3466178 DOI: 10.1073/Pnas.83.23.9129  0.327
1987 Bernards R, Dessain SK, Weinberg RA. N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma. Cell. 47: 667-74. PMID 3096575 DOI: 10.1016/0092-8674(86)90509-X  0.309
1987 Stern DF, Heffernan PA, Weinberg RA. p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity. Molecular and Cellular Biology. 6: 1729-40. PMID 2878363 DOI: 10.1128/MCB.6.5.1729  0.515
1986 Bargmann CI, Hung MC, Weinberg RA. The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature. 319: 226-30. PMID 3945311 DOI: 10.1038/319226A0  0.645
1986 Land H, Chen AC, Morgenstern JP, Parada LF, Weinberg RA. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. 6: 1917-25. PMID 3785184 DOI: 10.1128/Mcb.6.6.1917  0.558
1986 McCoy MS, Weinberg RA. A human Ki-ras oncogene encodes two transforming p21 proteins. Molecular and Cellular Biology. 6: 1326-8. PMID 3537700 DOI: 10.1128/Mcb.6.4.1326  0.354
1986 Gilman MZ, Wilson RN, Weinberg RA. Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression. Molecular and Cellular Biology. 6: 4305-16. PMID 3025651  0.522
1986 Stern DF, Roberts AB, Roche NS, Sporn MB, Weinberg RA. Differential responsiveness of myc- and ras-transfected cells to growth factors: Selective stimulation of myc-transfected cells by epidermal growth factor Molecular and Cellular Biology. 6: 870-877. PMID 3022135 DOI: 10.1128/Mcb.6.3.870  0.529
1986 Hung MC, Schechter AL, Chevray PYM, Stern DF, Weinberg RA. Molecular cloning of the neu gene: Absence of gross structural alteration in oncogenic alleles Proceedings of the National Academy of Sciences of the United States of America. 83: 261-264. PMID 3001730 DOI: 10.1073/Pnas.83.2.261  0.658
1986 Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma Nature. 323: 643-646. PMID 2877398 DOI: 10.1038/323643A0  0.328
1986 Bargmann CI, Hung MC, Weinberg RA. Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell. 45: 649-57. PMID 2871941 DOI: 10.1016/0092-8674(86)90779-8  0.649
1986 Dotto GP, Gilman MZ, Maruyama M, Weinberg RA. c-myc and c-fos expression in differentiating mouse primary keratinocytes. The Embo Journal. 5: 2853-7. PMID 2431900  0.543
1985 Dotto GP, Parada LF, Weinberg RA. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature. 318: 472-5. PMID 4069218 DOI: 10.1038/318472A0  0.563
1985 Parada LF, Land H, Chen A, Morganstern J, Weinberg RA. Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. Progrã¨S En Virologie Mã©Dicale. 32: 115-28. PMID 4023262  0.439
1985 Bernstein SC, Weinberg RA. Expression of the metastatic phenotype in cells transfected with human metastatic tumor DNA. Proceedings of the National Academy of Sciences of the United States of America. 82: 1726-30. PMID 3856854 DOI: 10.1073/Pnas.82.6.1726  0.394
1985 Weinberg RA. The action of oncogenes in the cytoplasm and nucleus. Science (New York, N.Y.). 230: 770-6. PMID 2997917 DOI: 10.1126/Science.2997917  0.385
1985 Schechter AL, Hung MC, Vaidyanathan L, Weinberg RA, Yang-Feng TL, Francke U, Ullrich A, Coussens L. The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor Science. 229: 976-978. PMID 2992090 DOI: 10.1126/Science.2992090  0.467
1985 Tabin CJ, Weinberg RA. Analysis of viral and somatic activations of the cHa-ras gene. Journal of Virology. 53: 260-5. PMID 2981345 DOI: 10.1128/Jvi.53.1.260-265.1985  0.569
1985 Drebin JA, Link VC, Stern DF, Weinberg RA, Greene MI. Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies Cell. 41: 695-706. PMID 2860972 DOI: 10.1016/S0092-8674(85)80050-7  0.578
1984 Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature. 312: 649-51. PMID 6390217 DOI: 10.1038/312649A0  0.589
1984 Schechter AL, Stern DF, Vaidyanathan L, Decker SJ, Drebin JA, Greene MI, Weinberg RA. The neu oncogene: An erb-B-related gene encoding a 185,000-M(r) tumour antigen Nature. 312: 513-516. PMID 6095109 DOI: 10.1038/312513A0  0.314
1984 McCoy MS, Bargmann CI, Weinberg RA. Human colon carcinoma Ki-ras2 oncogene and its corresponding proto-oncogene. Molecular and Cellular Biology. 4: 1577-82. PMID 6092920 DOI: 10.1128/Mcb.4.8.1577  0.604
1984 Lenoir GM, Land H, Parada LF, Cunningham JM, Weinberg RA. Activated oncogenes in Burkitt's lymphoma. Current Topics in Microbiology and Immunology. 113: 6-14. PMID 6090072 DOI: 10.1007/978-3-642-69860-6_2  0.543
1983 Weinberg RA. Alteration of the genomes of tumor cells. Cancer. 51: 1971-5. PMID 6839289 DOI: 10.1002/1097-0142(19830601)51:11<1971::Aid-Cncr2820511102>3.0.Co;2-V  0.443
1983 Sakaguchi AY, Naylor SL, Shows TB, Toole JJ, McCoy M, Weinberg RA. Human c-Ki-ras2 proto-oncogene on chromosome 12 Science. 219: 1081-1083. PMID 6823569 DOI: 10.1126/Science.6823569  0.339
1983 Murray MJ, Cunningham JM, Parada LF, Dautry F, Lebowitz P, Weinberg RA. The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell. 33: 749-57. PMID 6683594 DOI: 10.1016/0092-8674(83)90017-X  0.594
1983 Parada LF, Shih C, Murray M, Weinberg RA. The oncogene of a human bladder carcinoma. Progress in Nucleic Acid Research and Molecular Biology. 29: 269-72. PMID 6665172 DOI: 10.1016/S0079-6603(08)60458-4  0.549
1983 Land H, Parada LF, Weinberg RA. Cellular oncogenes and multistep carcinogenesis. Science (New York, N.Y.). 222: 771-8. PMID 6356358 DOI: 10.1126/Science.6356358  0.576
1983 Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304: 596-602. PMID 6308472 DOI: 10.1038/304596A0  0.559
1983 McCoy MS, Toole JJ, Cunningham JM, Chang EH, Lowy DR, Weinberg RA. Characterization of a human colon/lung carcinoma oncogene. Nature. 302: 79-81. PMID 6298638 DOI: 10.1038/302079A0  0.415
1983 de Martinville B, Giacalone J, Shih C, Weinberg RA, Francke U. Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11 Science. 219: 498-501. PMID 6297001 DOI: 10.1126/Science.6297001  0.344
1983 Parada LF, Weinberg RA. Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene. Molecular and Cellular Biology. 3: 2298-301. PMID 6197628  0.518
1983 Hoffmann JW, Steffen D, Gusella J, Tabin C, Bird S, Cowing D, Weinberg RA. DNA methylation affecting the expression of murine leukemia proviruses. Journal of Virology. 44: 144-57. PMID 6183444 DOI: 10.1128/Jvi.44.1.144-157.1982  0.539
1982 Padhy LC, Shih C, Cowing D, Finkelstein R, Weinberg RA. Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas. Cell. 28: 865-71. PMID 7094016 DOI: 10.1016/0092-8674(82)90065-4  0.364
1982 Weinberg RA. Fewer and fewer oncogenes. Cell. 30: 3-4. PMID 6751559 DOI: 10.1016/0092-8674(82)90003-4  0.315
1982 Weinberg RA. Oncogenes of spontaneous and chemically induced tumors. Advances in Cancer Research. 36: 149-163. PMID 6751037 DOI: 10.1016/S0065-230X(08)60424-8  0.334
1982 Tabin CJ, Bradley SM, Bargmann CI, Weinberg RA, Papageorge AG, Scolnick EM, Dhar R, Lowy DR, Chang EH. Mechanism of activation of a human oncogene. Nature. 300: 143-9. PMID 6290897 DOI: 10.1038/300143A0  0.681
1982 Shih C, Weinberg RA. Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell. 29: 161-9. PMID 6286138 DOI: 10.1016/0092-8674(82)90100-3  0.391
1982 Parada LF, Tabin CJ, Shih C, Weinberg RA. Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature. 297: 474-8. PMID 6283357 DOI: 10.1038/297474A0  0.666
1982 Goff SP, Tabin CJ, Wang JY, Weinberg R, Baltimore D. Transfection of fibroblasts by cloned Abelson murine leukemia virus DNA and recovery of transmissible virus by recombination with helper virus. Journal of Virology. 41: 271-85. PMID 6283119 DOI: 10.1128/Jvi.41.1.271-285.1982  0.63
1982 Tabin CJ, Hoffmann JW, Goff SP, Weinberg RA. Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene. Molecular and Cellular Biology. 2: 426-36. PMID 6180306 DOI: 10.1128/Mcb.2.4.426  0.559
1982 Weinberg RA. Oncogenes of human tumor cells Trends in Biochemical Sciences. 7: 135-136. DOI: 10.1016/0968-0004(82)90203-1  0.398
1981 Coffin JM, Varmus HE, Bishop JM, Essex M, Hardy WD, Martin GS, Rosenberg NE, Scolnick EM, Weinberg RA, Vogt PK. Proposal for naming host cell-derived inserts in retrovirus genomes. Journal of Virology. 40: 953-7. PMID 7321107 DOI: 10.1128/Jvi.40.3.953-957.1981  0.488
1981 Goldfarb MP, Weinberg RA. Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination. Journal of Virology. 38: 136-50. PMID 7241647  0.454
1981 Goldfarb MP, Weinberg RA. Structure of the provirus within NIH 3T3 cells transfected with Harvey sarcoma virus DNA. Journal of Virology. 38: 125-35. PMID 7241646  0.499
1981 Shih C, Padhy LC, Murray M, Weinberg RA. Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts. Nature. 290: 261-4. PMID 7207618 DOI: 10.1038/290261A0  0.376
1981 Weinberg RA, Steffen DL. Regulation of expression of the integrated retrovirus genome. The Journal of General Virology. 54: 1-8. PMID 7026730 DOI: 10.1099/0022-1317-54-1-1  0.308
1981 Murray MJ, Shilo BZ, Shih C, Cowing D, Hsu HW, Weinberg RA. Three different human tumor cell lines contain different oncogenes Cell. 25: 355-361. PMID 6269741 DOI: 10.1016/0092-8674(81)90054-4  0.382
1981 Shilo BZ, Weinberg RA. Unique transforming gene in carcinogen-transformed mouse cells Nature. 289: 607-609. PMID 6258087 DOI: 10.1038/289607A0  0.332
1980 Donoghue DJ, Goldfarb MP, Sharp PA, Weinberg RA. Organization of murine sarcoma virus genomes. Cold Spring Harbor Symposia On Quantitative Biology. 44: 721-6. PMID 6253206 DOI: 10.1101/Sqb.1980.044.01.077  0.458
1979 Steffen D, Andersson P, Goldfarb M, Weinberg RA. Integration and possible transduction by retroviruses. Cold Spring Harbor Symposia On Quantitative Biology. 43: 875-9. PMID 290450 DOI: 10.1101/Sqb.1979.043.01.094  0.442
1979 Goldfarb MP, Weinberg RA. Physical map of biologically active Harvey sarcoma virus unintegrated linear DNA. Journal of Virology. 32: 30-9. PMID 232180  0.437
1979 Shih C, Shilo BZ, Goldfarb MP, Dannenberg A, Weinberg RA. Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin. Proceedings of the National Academy of Sciences of the United States of America. 76: 5714-8. PMID 230490 DOI: 10.1073/Pnas.76.11.5714  0.526
1979 Andersson P, Goldfarb MP, Weinberg RA. A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection. Cell. 16: 63-75. PMID 84715 DOI: 10.1016/0092-8674(79)90188-0  0.519
1978 Philipson L, Andersson P, Olshevsky U, Weinberg R, Baltimore D, Gesteland R. Translation of MuLV and MSV RNAs in nuclease-treated reticulocyte extracts: Enhancement of the gag-pol polypeptide with yeast suppressor tRNA Cell. 13: 189-199. PMID 202399 DOI: 10.1016/0092-8674(78)90149-6  0.311
1977 Rothenberg E, Smotkin D, Baltimore D, Weinberg RA. In vitro synthesis of infectious DNA of murine leukaemia virus. Nature. 269: 122-6. PMID 71657 DOI: 10.1038/269122A0  0.448
1975 Paskind MP, Weinberg RA, Baltimore D. Dependence of Moloney murine leukemia virus production on cell growth. Virology. 67: 242-8. PMID 1172324 DOI: 10.1016/0042-6822(75)90421-3  0.46
1974 Lodish HF, Weinberg R, Ozer HL. Translation of mRNA from simian virus 40-infected cells into simian virus 40 capsid protein by cell-free extracts. Journal of Virology. 13: 590-5. PMID 4362863 DOI: 10.1128/Jvi.13.3.590-595.1974  0.318
1974 Besmer P, Smotkin D, Haseltine W, Fan H, Wilson AT, Paskind M, Weinberg R, Baltimore D. Mechanism of induction of RNA tumor viruses by halogenated pyrimidines. Cold Spring Harbor Symposia On Quantitative Biology. 39: 1103-1107. PMID 1057469 DOI: 10.1101/Sqb.1974.039.01.125  0.521
1973 Leibowitz RD, Weinberg RA, Penman S. Unusual metabolism of 5 S RNA in HeLa cells. Journal of Molecular Biology. 73: 139-44. PMID 4690307 DOI: 10.1016/0022-2836(73)90166-6  0.51
1972 Weinberg RA, Warnaar SO, Winocour E. Isolation and characterization of simian virus 40 ribonucleic acid. Journal of Virology. 10: 193-201. PMID 4342237  0.59
1970 Weinberg RA, Penman S. Processing of 45 s nucleolar RNA. Journal of Molecular Biology. 47: 169-78. PMID 4314037 DOI: 10.1016/0022-2836(70)90337-2  0.488
1970 Penman S, Fan H, Perlman S, Rosbash M, Weinberg R, Zylber E. Distinct RNA Synthesis Systems of the HeLa Cell Cold Spring Harbor Symposia On Quantitative Biology. 35: 561-575. DOI: 10.1101/Sqb.1970.035.01.072  0.629
1969 Siev M, Weinberg R, Penman S. The selective interruption of nucleolar RNA synthesis in HeLa cells by cordycepin. The Journal of Cell Biology. 41: 510-20. PMID 5783871 DOI: 10.1083/Jcb.41.2.510  0.507
1969 Penman S, Vesco C, Weinberg R, Zylber E. The RNA metabolism of nucleoli and mitochondria in mammalian cells. Cold Spring Harbor Symposia On Quantitative Biology. 34: 535-46. PMID 4314913 DOI: 10.1101/Sqb.1969.034.01.061  0.521
1969 Weinberg R, Penman S. Metabolism of small molecular weight monodisperse nuclear RNA. Biochimica Et Biophysica Acta. 190: 10-29. PMID 4186242 DOI: 10.1016/0005-2787(69)90150-6  0.512
1968 Weinberg RA, Penman S. Small molecular weight monodisperse nuclear RNA. Journal of Molecular Biology. 38: 289-304. PMID 5718554 DOI: 10.1016/0022-2836(68)90387-2  0.504
1967 Weinberg RA, Loening U, Willems M, Penman S. Acrylamide gel electrophoresis of HeLa cell nucleolar RNA. Proceedings of the National Academy of Sciences of the United States of America. 58: 1088-95. PMID 5233837 DOI: 10.1073/Pnas.58.3.1088  0.521
Show low-probability matches.