Year |
Citation |
Score |
2018 |
Jacques B, Coinçon M, Sygusch J. Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. The Journal of Biological Chemistry. PMID 29593097 DOI: 10.1074/Jbc.Ra117.001098 |
0.607 |
|
2017 |
Mohanty B, Rimmer K, McMahon RM, Headey SJ, Vazirani M, Shouldice SR, Coinçon M, Tay S, Morton CJ, Simpson JS, Martin JL, Scanlon MJ. Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. Plos One. 12: e0173436. PMID 28346540 DOI: 10.1371/journal.pone.0173436 |
0.305 |
|
2015 |
Tanner JE, Coinçon M, Leblond V, Hu J, Fang JM, Sygusch J, Alfieri C. Peptides designed to spatially depict the Epstein-Barr virus major virion glycoprotein gp350 neutralization epitope elicit antibodies that block virus-neutralizing antibody 72A1 interaction with the native gp350 molecule. Journal of Virology. 89: 4932-41. PMID 25694592 DOI: 10.1128/Jvi.03269-14 |
0.508 |
|
2012 |
Smith MA, Coinçon M, Paschos A, Jolicoeur B, Lavallée P, Sygusch J, Baron C. Identification of the binding site of Brucella VirB8 interaction inhibitors. Chemistry & Biology. 19: 1041-8. PMID 22921071 DOI: 10.1016/J.Chembiol.2012.07.007 |
0.607 |
|
2012 |
Coincon M, Wang W, Sygusch J, Seah SY. Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity. The Journal of Biological Chemistry. 287: 36208-21. PMID 22908224 DOI: 10.1074/Jbc.M112.400705 |
0.604 |
|
2011 |
de la Paz Santangelo M, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R, Lenaerts AJ, Schnappinger D, Therisod M, Ehrt S, Sygusch J, et al. Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli. The Journal of Biological Chemistry. 286: 40219-31. PMID 21949126 DOI: 10.1074/Jbc.M111.259440 |
0.596 |
|
2010 |
Daher R, Coinçon M, Fonvielle M, Gest PM, Guerin ME, Jackson M, Sygusch J, Therisod M. Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. Journal of Medicinal Chemistry. 53: 7836-42. PMID 20929256 DOI: 10.1021/Jm1009814 |
0.616 |
|
2009 |
Starnes GL, Coincon M, Sygusch J, Sibley LD. Aldolase is essential for energy production and bridging adhesin-actin cytoskeletal interactions during parasite invasion of host cells. Cell Host & Microbe. 5: 353-64. PMID 19380114 DOI: 10.1016/J.Chom.2009.03.005 |
0.556 |
|
2008 |
Fonvielle M, Coinçon M, Daher R, Desbenoit N, Kosieradzka K, Barilone N, Gicquel B, Sygusch J, Jackson M, Therisod M. Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 8521-9. PMID 18688832 DOI: 10.1002/Chem.200800857 |
0.606 |
|
2006 |
Dax C, Duffieux F, Chabot N, Coincon M, Sygusch J, Michels PA, Blonski C. Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei. Journal of Medicinal Chemistry. 49: 1499-502. PMID 16509566 DOI: 10.1021/Jm050237B |
0.606 |
|
2005 |
Dax C, Coinçon M, Sygusch J, Blonski C. Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase. Biochemistry. 44: 5430-43. PMID 15807536 DOI: 10.1021/Bi0477992 |
0.619 |
|
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