| Year |
Citation |
Score |
| 2020 |
Falcicchia C, Tozzi F, Arancio O, Watterson DM, Origlia N. Involvement of p38 MAPK in Synaptic Function and Dysfunction. International Journal of Molecular Sciences. 21. PMID 32781522 DOI: 10.3390/Ijms21165624 |
0.344 |
|
| 2020 |
Roy SM, Minasov G, Arancio O, Chico LW, Van Eldik LJ, Anderson WF, Pelletier JC, Watterson DM. Correction to "A Selective and Brain Penetrant p38αMAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction". Journal of Medicinal Chemistry. PMID 32672466 DOI: 10.1021/Acs.Jmedchem.0C01060 |
0.496 |
|
| 2019 |
Roy SM, Minasov G, Arancio O, Chico LW, Van Eldik LJ, Anderson WF, Pelletier JC, Watterson DM. A Selective and Brain Penetrant p38αMAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction. Journal of Medicinal Chemistry. PMID 30978288 DOI: 10.1021/Acs.Jmedchem.9B00058 |
0.56 |
|
| 2019 |
Bailey A, Suri A, Tavares M, Roy S, Tomita T, Kosikowski A, Watterson D, Sredni S. THER-09. EVALUATION OF PROTEIN KINASE INHIBITORS WITH PLK4 CROSS-OVER POTENTIAL IN PEDIATRIC EMBRYONAL BRAIN TUMORS Neuro-Oncology. 21: ii115-ii116. DOI: 10.1093/Neuonc/Noz036.216 |
0.37 |
|
| 2018 |
Rutigliano G, Stazi M, Arancio O, Watterson DM, Origlia N. An isoform-selective p38α mitogen-activated protein kinase inhibitor rescues early entorhinal cortex dysfunctions in a mouse model of Alzheimer's disease. Neurobiology of Aging. 70: 86-91. PMID 30007168 DOI: 10.1016/J.Neurobiolaging.2018.06.006 |
0.306 |
|
| 2017 |
Sredni ST, Bailey AW, Suri A, Hashizume R, He X, Louis N, Gokirmak T, Piper DR, Watterson DM, Tomita T. Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma. Oncotarget. 8: 111190-111212. PMID 29340047 DOI: 10.18632/Oncotarget.22704 |
0.332 |
|
| 2017 |
Zhou Z, Bachstetter AD, Späni CB, Roy SM, Watterson DM, Van Eldik LJ. Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes. Journal of Neuroinflammation. 14: 75. PMID 28381303 DOI: 10.1186/S12974-017-0845-2 |
0.743 |
|
| 2016 |
Maphis N, Jiang S, Xu G, Kokiko-Cochran ON, Roy SM, Van Eldik LJ, Watterson DM, Lamb BT, Bhaskar K. Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology. Alzheimer's Research & Therapy. 8: 54. PMID 27974048 DOI: 10.1186/S13195-016-0221-Y |
0.546 |
|
| 2016 |
Bachstetter AD, Zhou Z, Rowe RK, Xing B, Goulding DS, Conley AN, Sompol P, Meier S, Abisambra JF, Lifshitz J, Watterson DM, Van Eldik LJ. MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses. Plos One. 11: e0149451. PMID 26871438 DOI: 10.1371/Journal.Pone.0149451 |
0.683 |
|
| 2016 |
Van Eldik LJ, Zhou Z, Watterson DM, Bachstetter AD. P2-129: A Small Molecule Anti-Neuroinflammatory Experimental Therapeutic Inhibited IL-1Beta Levels After Traumatic Brain Injury with no Effect on Microglia Physiological Responses Alzheimer's & Dementia. 12: P661-P661. DOI: 10.1016/J.Jalz.2016.06.1499 |
0.606 |
|
| 2015 |
Webster SJ, Van Eldik LJ, Watterson DM, Bachstetter AD. Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6554-69. PMID 25904805 DOI: 10.1523/Jneurosci.0291-15.2015 |
0.678 |
|
| 2015 |
Bachstetter AD, Webster SJ, Goulding DS, Morton JE, Watterson DM, Van Eldik LJ. Attenuation of traumatic brain injury-induced cognitive impairment in mice by targeting increased cytokine levels with a small molecule experimental therapeutic. Journal of Neuroinflammation. 12: 69. PMID 25886256 DOI: 10.1186/S12974-015-0289-5 |
0.694 |
|
| 2015 |
Roy SM, Grum-Tokars VL, Schavocky JP, Saeed F, Staniszewski A, Teich AF, Arancio O, Bachstetter AD, Webster SJ, Van Eldik LJ, Minasov G, Anderson WF, Pelletier JC, Watterson DM. Targeting human central nervous system protein kinases: An isoform selective p38αMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models. Acs Chemical Neuroscience. 6: 666-80. PMID 25676389 DOI: 10.1021/Acschemneuro.5B00002 |
0.738 |
|
| 2014 |
Bachstetter AD, Webster SJ, Tu T, Goulding DS, Haiech J, Watterson DM, Van Eldik LJ. Generation and behavior characterization of CaMKIIβ knockout mice. Plos One. 9: e105191. PMID 25127391 DOI: 10.1371/Journal.Pone.0105191 |
0.688 |
|
| 2014 |
Bachstetter AD, Watterson DM, Van Eldik LJ. Target engagement analysis and link to pharmacodynamic endpoint for a novel class of CNS-penetrant and efficacious p38α MAPK inhibitors. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 454-60. PMID 24789302 DOI: 10.1007/S11481-014-9543-3 |
0.731 |
|
| 2013 |
Watterson DM, Grum-Tokars VL, Roy SM, Schavocky JP, Bradaric BD, Bachstetter AD, Xing B, Dimayuga E, Saeed F, Zhang H, Staniszewski A, Pelletier JC, Minasov G, Anderson WF, Arancio O, et al. Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction. Plos One. 8: e66226. PMID 23840427 DOI: 10.1371/Journal.Pone.0066226 |
0.744 |
|
| 2012 |
Chico LK, Watterson DM. The 6th drug discovery for neurodegeneration conference: an intensive course on translating research into drugs. Expert Opinion On Drug Discovery. 7: 1225-8. PMID 23092534 DOI: 10.1517/17460441.2012.733692 |
0.325 |
|
| 2012 |
Bachstetter AD, Norris CM, Sompol P, Wilcock DM, Goulding D, Neltner JH, St Clair D, Watterson DM, Van Eldik LJ. Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10201-10. PMID 22836255 DOI: 10.1523/Jneurosci.1496-12.2012 |
0.706 |
|
| 2012 |
Van Eldik L, Bachstetter A, Sompol P, St. Clair D, Watterson DM. P2-382: Targeting proinflammatory cytokine up-regulation with a novel anti-cytokine therapeutic, MW-151, attenuates pathology in an APP/PS1 knock-in mouse model Alzheimer's & Dementia. 8: P397-P397. DOI: 10.1016/J.Jalz.2012.05.1092 |
0.611 |
|
| 2012 |
Van Eldik LJ, Watterson DM. Calmodulin and Calcium Signal Transduction: An Introduction Calmodulin and Signal Transduction. 1-15. DOI: 10.1016/B978-0-08-092636-0.50005-0 |
0.439 |
|
| 2012 |
Van Eldik LJ, Watterson DM. Preface Calmodulin and Signal Transduction. xi-xiv. DOI: 10.1016/B978-0-08-092636-0.50004-9 |
0.38 |
|
| 2012 |
Van Eldik LJ, Watterson DM. Calmodulin and Signal Transduction Calmodulin and Signal Transduction. 1-482. |
0.422 |
|
| 2011 |
Bachstetter AD, Xing B, de Almeida L, Dimayuga ER, Watterson DM, Van Eldik LJ. Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ). Journal of Neuroinflammation. 8: 79. PMID 21733175 DOI: 10.1186/1742-2094-8-79 |
0.723 |
|
| 2011 |
McNamara LK, Brunzelle JS, Schavocky JP, Watterson DM, Grum-Tokars V. Site-directed mutagenesis of the glycine-rich loop of death associated protein kinase (DAPK) identifies it as a key structure for catalytic activity. Biochimica Et Biophysica Acta. 1813: 1068-73. PMID 21126544 DOI: 10.1016/J.Bbamcr.2010.11.011 |
0.779 |
|
| 2010 |
Zimmermann M, Atmanene C, Xu Q, Fouillen L, Van Dorsselaer A, Bonnet D, Marsol C, Hibert M, Sanglier-Cianferani S, Pigault C, McNamara LK, Watterson DM, Haiech J, Kilhoffer MC. Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter. Plos One. 5: e14120. PMID 21152427 DOI: 10.1371/Journal.Pone.0014120 |
0.8 |
|
| 2009 |
Chico LK, Van Eldik LJ, Watterson DM. Targeting protein kinases in central nervous system disorders. Nature Reviews. Drug Discovery. 8: 892-909. PMID 19876042 DOI: 10.1038/nrd2999 |
0.599 |
|
| 2009 |
Marchenko AV, Sidorova MV, Sekridova AV, Bushuev VN, Lakomkin VL, Orlova TsR, Stepanova OV, Kapel'ko VI, Watterson DM, Van Eldik LJ, Bespalova ZhD, ShirinskiÄ VP. [Penetrating peptide inhibitor of the myosin light chain kinase suppresses hyperpermeability of vascular endothelium]. RossiäSkii Fiziologicheskiä Zhurnal Imeni I.M. Sechenova / RossiäSkaia Akademiia Nauk. 95: 507-15. PMID 19569527 |
0.459 |
|
| 2009 |
Somera-Molina KC, Nair S, Van Eldik LJ, Watterson DM, Wainwright MS. Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model. Brain Research. 1282: 162-72. PMID 19501063 DOI: 10.1016/J.Brainres.2009.05.073 |
0.462 |
|
| 2009 |
McNamara LK, Watterson DM, Brunzelle JS. Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallographica. Section D, Biological Crystallography. 65: 241-8. PMID 19237746 DOI: 10.1107/S0907444908043679 |
0.794 |
|
| 2008 |
Borders AS, de Almeida L, Van Eldik LJ, Watterson DM. The p38alpha mitogen-activated protein kinase as a central nervous system drug discovery target. Bmc Neuroscience. 9: S12. PMID 19090985 DOI: 10.1186/1471-2202-9-S2-S12 |
0.606 |
|
| 2008 |
Karpus WJ, Reynolds N, Behanna HA, Van Eldik LJ, Watterson DM. Inhibition of experimental autoimmune encephalomyelitis by a novel small molecular weight proinflammatory cytokine suppressing drug. Journal of Neuroimmunology. 203: 73-8. PMID 18678415 DOI: 10.1016/J.Jneuroim.2008.06.039 |
0.505 |
|
| 2008 |
Lloyd E, Somera-Molina K, Van Eldik LJ, Watterson DM, Wainwright MS. Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury. Journal of Neuroinflammation. 5: 28. PMID 18590543 DOI: 10.1186/1742-2094-5-28 |
0.514 |
|
| 2008 |
McNamara LK, Schavocky JP, Brunzelle JS, Watterson DM. P3-304: Death associated protein kinase (DAPK): A calcium/calmodulin (CAM) regulator of neuronal apoptosis that is a drug discovery target for neurodegenerative disorders Alzheimer's & Dementia. 4: T611-T611. DOI: 10.1016/J.Jalz.2008.05.1873 |
0.788 |
|
| 2008 |
Borders AS, McNamara LK, Roy SM, Chico LW, Pishchulina A, de Almeida LM, Van Eldik LJ, Watterson DM. P2-419: Development of novel protein kinase inhibitors as experimental therapeutics for neurodegenerative disorders Alzheimer's & Dementia. 4: T496-T496. DOI: 10.1016/J.Jalz.2008.05.1498 |
0.791 |
|
| 2007 |
Munoz L, Ralay Ranaivo H, Roy SM, Hu W, Craft JM, McNamara LK, Chico LW, Van Eldik LJ, Watterson DM. A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model. Journal of Neuroinflammation. 4: 21. PMID 17784957 DOI: 10.1186/1742-2094-4-21 |
0.784 |
|
| 2007 |
Somera-Molina KC, Robin B, Somera CA, Anderson C, Stine C, Koh S, Behanna HA, Van Eldik LJ, Watterson DM, Wainwright MS. Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation. Epilepsia. 48: 1785-800. PMID 17521344 DOI: 10.1111/J.1528-1167.2007.01135.X |
0.462 |
|
| 2007 |
Hu W, Ralay Ranaivo H, Roy SM, Behanna HA, Wing LK, Munoz L, Guo L, Van Eldik LJ, Watterson DM. Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits. Bioorganic & Medicinal Chemistry Letters. 17: 414-8. PMID 17079143 DOI: 10.1016/J.Bmcl.2006.10.028 |
0.555 |
|
| 2007 |
Watterson D, Ranaivo HR, Behanna H, Roy SM, Wing LK, Hu W, Munoz L, Guo L, McNamara LK, Van Eldik LJ. P-014: Improving the CNS drug discovery process: Case study with an integrative approach yielding novel potential disease-modifying therapies Alzheimer's & Dementia. 3: S99-S99. DOI: 10.1016/J.Jalz.2007.04.230 |
0.754 |
|
| 2006 |
Schumacher AM, Velentza AV, Watterson DM, Dresios J. Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis. Biochemistry. 45: 13614-21. PMID 17087515 DOI: 10.1021/bi060413y |
0.317 |
|
| 2006 |
Behanna HA, Watterson DM, Ralay Ranaivo H. Development of a novel bioavailable inhibitor of the calmodulin-regulated protein kinase MLCK: a lead compound that attenuates vascular leak. Biochimica Et Biophysica Acta. 1763: 1266-74. PMID 16996151 DOI: 10.1016/J.Bbamcr.2006.08.007 |
0.326 |
|
| 2006 |
Wing LK, Behanna HA, Van Eldik LJ, Watterson DM, Ralay Ranaivo H. De novo and molecular target-independent discovery of orally bioavailable lead compounds for neurological disorders. Current Alzheimer Research. 3: 205-14. PMID 16842097 DOI: 10.2174/156720506777632844 |
0.502 |
|
| 2006 |
Ralay Ranaivo H, Craft JM, Hu W, Guo L, Wing LK, Van Eldik LJ, Watterson DM. Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 662-70. PMID 16407564 DOI: 10.1523/JNEUROSCI.4652-05.2006 |
0.549 |
|
| 2006 |
Craft JM, Watterson DM, Van Eldik LJ. Human amyloid beta-induced neuroinflammation is an early event in neurodegeneration. Glia. 53: 484-90. PMID 16369931 DOI: 10.1002/glia.20306 |
0.535 |
|
| 2005 |
Craft JM, Watterson DM, Van Eldik LJ. Neuroinflammation: a potential therapeutic target. Expert Opinion On Therapeutic Targets. 9: 887-900. PMID 16185146 DOI: 10.1517/14728222.9.5.887 |
0.548 |
|
| 2005 |
Clayburgh DR, Barrett TA, Tang Y, Meddings JB, Van Eldik LJ, Watterson DM, Clarke LL, Mrsny RJ, Turner JR. Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. The Journal of Clinical Investigation. 115: 2702-15. PMID 16184195 DOI: 10.1172/Jci24970 |
0.518 |
|
| 2005 |
Hu W, Ralay Ranaivo H, Craft JM, Van Eldik LJ, Watterson DM. Validation of the neuroinflammation cycle as a drug discovery target using integrative chemical biology and lead compound development with an Alzheimer's disease-related mouse model. Current Alzheimer Research. 2: 197-205. PMID 15974919 DOI: 10.2174/1567205053585828 |
0.521 |
|
| 2005 |
Craft JM, Watterson DM, Hirsch E, Van Eldik LJ. Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human beta-amyloid. Journal of Neuroinflammation. 2: 15. PMID 15967035 DOI: 10.1186/1742-2094-2-15 |
0.498 |
|
| 2005 |
Craft JM, Watterson DM, Marks A, Van Eldik LJ. Enhanced susceptibility of S-100B transgenic mice to neuroinflammation and neuronal dysfunction induced by intracerebroventricular infusion of human beta-amyloid. Glia. 51: 209-16. PMID 15810011 DOI: 10.1002/glia.20194 |
0.479 |
|
| 2004 |
Craft JM, Watterson DM, Frautschy SA, Van Eldik LJ. Aminopyridazines inhibit beta-amyloid-induced glial activation and neuronal damage in vivo. Neurobiology of Aging. 25: 1283-92. PMID 15465624 DOI: 10.1016/j.neurobiolaging.2004.01.006 |
0.518 |
|
| 2004 |
Craft JM, Van Eldik LJ, Zasadzki M, Hu W, Watterson DM. Aminopyridazines attenuate hippocampus-dependent behavioral deficits induced by human beta-amyloid in a murine model of neuroinflammation. Journal of Molecular Neuroscience : Mn. 24: 115-22. PMID 15314259 DOI: 10.1385/JMN:24:1:115 |
0.53 |
|
| 2004 |
Kudryashov DS, Stepanova OV, Vilitkevich EL, Nikonenko TA, Nadezhdina ES, Shanina NA, Lukas TJ, Van Eldik LJ, Watterson DM, Shirinsky VP. Myosin light chain kinase (210 kDa) is a potential cytoskeleton integrator through its unique N-terminal domain. Experimental Cell Research. 298: 407-17. PMID 15265689 DOI: 10.1016/j.yexcr.2004.04.025 |
0.492 |
|
| 2004 |
Schumacher AM, Schavocky JP, Velentza AV, Mirzoeva S, Watterson DM. A calmodulin-regulated protein kinase linked to neuron survival is a substrate for the calmodulin-regulated death-associated protein kinase. Biochemistry. 43: 8116-24. PMID 15209507 DOI: 10.1021/bi049589v |
0.334 |
|
| 2003 |
Velentza AV, Wainwright MS, Zasadzki M, Mirzoeva S, Schumacher AM, Haiech J, Focia PJ, Egli M, Watterson DM. An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury. Bioorganic & Medicinal Chemistry Letters. 13: 3465-70. PMID 14505650 DOI: 10.1016/S0960-894X(03)00733-9 |
0.33 |
|
| 2003 |
Watterson DM, Velentza AV, Zasadzki M, Craft JM, Haiech J, Van Eldik LJ. Discovery of a new class of synthetic protein kinase inhibitors that suppress selective aspects of glial activation and protect against beta-amyloid induced injury: a foundation for future medicinal chemistry efforts focused on targeting Alzheimer's disease progression. Journal of Molecular Neuroscience : Mn. 20: 411-23. PMID 14501026 DOI: 10.1385/JMN:20:3:411 |
0.588 |
|
| 2003 |
Wainwright MS, Rossi J, Schavocky J, Crawford S, Steinhorn D, Velentza AV, Zasadzki M, Shirinsky V, Jia Y, Haiech J, Van Eldik LJ, Watterson DM. Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment. Proceedings of the National Academy of Sciences of the United States of America. 100: 6233-8. PMID 12730364 DOI: 10.1073/Pnas.1031595100 |
0.549 |
|
| 2002 |
Schumacher AM, Velentza AV, Watterson DM. Death-associated protein kinase as a potential therapeutic target. Expert Opinion On Therapeutic Targets. 6: 497-506. PMID 12223064 DOI: 10.1517/14728222.6.4.497 |
0.368 |
|
| 2002 |
Watterson DM, Haiech J, Van Eldik LJ. Discovery of new chemical classes of synthetic ligands that suppress neuroinflammatory responses. Journal of Molecular Neuroscience : Mn. 19: 89-93. PMID 12212800 DOI: 10.1007/s12031-002-0016-4 |
0.56 |
|
| 2002 |
Velentza AV, Schumacher AM, Watterson DM. Structure, activity, regulation, and inhibitor discovery for a protein kinase associated with apoptosis and neuronal death. Pharmacology & Therapeutics. 93: 217-24. PMID 12191613 |
0.314 |
|
| 2002 |
Van Eldik LJ, Koppal T, Watterson DM. Barriers to Alzheimer disease drug discovery and development in academia. Alzheimer Disease and Associated Disorders. 16: S18-28. PMID 12070358 |
0.489 |
|
| 2002 |
Mirzoeva S, Sawkar A, Zasadzki M, Guo L, Velentza AV, Dunlap V, Bourguignon JJ, Ramstrom H, Haiech J, Van Eldik LJ, Watterson DM. Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic antineuroinflammatory compound. Journal of Medicinal Chemistry. 45: 563-6. PMID 11806708 DOI: 10.1021/jm015573g |
0.57 |
|
| 2001 |
Guo L, Sawkar A, Zasadzki M, Watterson DM, Van Eldik LJ. Similar activation of glial cultures from different rat brain regions by neuroinflammatory stimuli and downregulation of the activation by a new class of small molecule ligands. Neurobiology of Aging. 22: 975-81. PMID 11755006 DOI: 10.1016/S0197-4580(01)00295-0 |
0.526 |
|
| 2001 |
Lam AG, Koppal T, Akama KT, Guo L, Craft JM, Samy B, Schavocky JP, Watterson DM, Van Eldik LJ. Mechanism of glial activation by S100B: involvement of the transcription factor NFkappaB. Neurobiology of Aging. 22: 765-72. PMID 11705636 DOI: 10.1016/S0197-4580(01)00233-0 |
0.516 |
|
| 2001 |
Watterson DM, Mirzoeva S, Guo L, Whyte A, Bourguignon JJ, Hibert M, Haiech J, Van Eldik LJ. Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1 beta and nitric oxide synthase II. Neurochemistry International. 39: 459-68. PMID 11578781 DOI: 10.1016/S0197-0186(01)00053-5 |
0.579 |
|
| 1999 |
Kudryashov DS, Chibalina MV, Birukov KG, Lukas TJ, Sellers JR, Van Eldik LJ, Watterson DM, Shirinsky VP. Unique sequence of a high molecular weight myosin light chain kinase is involved in interaction with actin cytoskeleton. Febs Letters. 463: 67-71. PMID 10601640 DOI: 10.1016/S0014-5793(99)01591-4 |
0.477 |
|
| 1999 |
Watterson DM, Schavocky JP, Guo L, Weiss C, Chlenski A, Shirinsky VP, Van Eldik LJ, Haiech J. Analysis of the kinase-related protein gene found at human chromosome 3q21 in a multi-gene cluster: organization, expression, alternative splicing, and polymorphic marker. Journal of Cellular Biochemistry. 75: 481-91. PMID 10536370 DOI: 10.1002/(SICI)1097-4644(19991201)75:3<481::AID-JCB12>3.0.CO;2-5 |
0.487 |
|
| 1999 |
Mirzoeva S, Koppal T, Petrova TV, Lukas TJ, Watterson DM, Van Eldik LJ. Screening in a cell-based assay for inhibitors of microglial nitric oxide production reveals calmodulin-regulated protein kinases as potential drug discovery targets. Brain Research. 844: 126-34. PMID 10536268 DOI: 10.1016/S0006-8993(99)01911-3 |
0.584 |
|
| 1998 |
Birukov KG, Schavocky JP, Shirinsky VP, Chibalina MV, Van Eldik LJ, Watterson DM. Organization of the genetic locus for chicken myosin light chain kinase is complex: multiple proteins are encoded and exhibit differential expression and localization. Journal of Cellular Biochemistry. 70: 402-13. PMID 9706877 DOI: 10.1002/(SICI)1097-4644(19980901)70:3<402::AID-JCB13>3.0.CO;2-M |
0.526 |
|
| 1995 |
Watterson DM, Collinge M, Lukas TJ, Van Eldik LJ, Birukov KG, Stepanova OV, Shirinsky VP. Multiple gene products are produced from a novel protein kinase transcription region. Febs Letters. 373: 217-20. PMID 7589469 DOI: 10.1016/0014-5793(95)01048-J |
0.536 |
|
| 1992 |
Collinge M, Matrisian PE, Zimmer WE, Shattuck RL, Lukas TJ, Van Eldik LJ, Watterson DM. Structure and expression of a calcium-binding protein gene contained within a calmodulin-regulated protein kinase gene. Molecular and Cellular Biology. 12: 2359-71. PMID 1373815 DOI: 10.1128/Mcb.12.5.2359 |
0.517 |
|
| 1990 |
Jiang K, Zheng J, Higgins SB, Watterson DM, Craig TA, Lukas TJ, Van Eldik LJ. A knowledge-based experimental design system for nucleic acid engineering. Computer Applications in the Biosciences : Cabios. 6: 205-12. PMID 2207744 DOI: 10.1093/bioinformatics/6.3.205 |
0.439 |
|
| 1990 |
Shoemaker MO, Lau W, Shattuck RL, Kwiatkowski AP, Matrisian PE, Guerra-Santos L, Wilson E, Lukas TJ, Van Eldik LJ, Watterson DM. Use of DNA sequence and mutant analyses and antisense oligodeoxynucleotides to examine the molecular basis of nonmuscle myosin light chain kinase autoinhibition, calmodulin recognition, and activity. The Journal of Cell Biology. 111: 1107-25. PMID 2202734 |
0.517 |
|
| 1990 |
Van Eldik LJ, Zimmer WE, Barger SW, Watterson DM. Perturbation of the calmodulin system in transformed cells. Advances in Experimental Medicine and Biology. 269: 111-20. PMID 2162134 DOI: 10.1007/978-1-4684-5754-4_18 |
0.496 |
|
| 1985 |
Van Eldik LJ, Lukas TJ, Watterson DM. Engineering of site-directed antibodies against plant calmodulin Federation Proceedings. 44: No. 1839. |
0.405 |
|
| 1984 |
Van Eldik LJ, Watterson DM, Burgess WH. Immunoreactive levels of myosin light-chain kinase in normal and virus-transformed chicken embryo fibroblasts. Molecular and Cellular Biology. 4: 2224-6. PMID 6390185 |
0.523 |
|
| 1984 |
Watterson DM, Burgess WH, Lukas TJ, Iverson D, Marshak DR, Schleicher M, Erickson BW, Fok KF, Van Eldik LJ. Towards a molecular and atomic anatomy of calmodulin and calmodulin-binding proteins. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 16: 205-26. PMID 6326525 |
0.538 |
|
| 1984 |
Zendegui JG, Zielinski RE, Watterson DM, Van Eldik LJ. Biosynthesis of calmodulin in normal and virus-transformed chicken embryo fibroblasts. Molecular and Cellular Biology. 4: 883-9. PMID 6203028 |
0.452 |
|
| 1984 |
Burgess WH, Watterson DM, Van Eldik LJ. Identification of calmodulin-binding proteins in chicken embryo fibroblasts. The Journal of Cell Biology. 99: 550-7. PMID 6086671 |
0.512 |
|
| 1983 |
Van Eldik LJ, Watterson DM, Fok KF, Erickson BW. Elucidation of a minimal immunoreactive site of vertebrate calmodulin. Archives of Biochemistry and Biophysics. 227: 522-33. PMID 6667029 DOI: 10.1016/0003-9861(83)90481-2 |
0.471 |
|
| 1983 |
Van Eldik LJ, Fok KF, Erickson BW, Watterson DM. Engineering of site-directed antisera against vertebrate calmodulin by using synthetic peptide immunogens containing an immunoreactive site. Proceedings of the National Academy of Sciences of the United States of America. 80: 6775-9. PMID 6196776 |
0.478 |
|
| 1982 |
Van Eldik LJ, Zendegui JG, Marshak DR, Watterson DM. Calcium-binding proteins and the molecular basis of calcium action. International Review of Cytology. 77: 1-61. PMID 6757171 |
0.463 |
|
| 1981 |
Marshak DR, Watterson DM, Van Eldik LJ. Calcium-dependent interaction of S100b, troponin C, and calmodulin with an immobilized phenothiazine. Proceedings of the National Academy of Sciences of the United States of America. 78: 6793-7. PMID 6947252 |
0.517 |
|
| 1981 |
Van Eldik LJ, Watterson DM. Reproducible production of antiserum against vertebrate calmodulin and determination of the immunoreactive site. The Journal of Biological Chemistry. 256: 4205-10. PMID 6163780 |
0.503 |
|
| 1980 |
Watterson DM, Iverson DB, Van Eldik LJ. Spinach calmodulin: isolation, characterization, and comparison with vertebrate calmodulins. Biochemistry. 19: 5762-8. PMID 7459343 |
0.505 |
|
| 1980 |
Van Eldik LJ, Watterson DM. Reproducible production and characterization of anti-calmodulin antisera. Annals of the New York Academy of Sciences. 356: 437-8. PMID 6940510 DOI: 10.1111/j.1749-6632.1980.tb29663.x |
0.438 |
|
| 1980 |
Marshak DR, Van Eldik LJ, Watterson DM. Isolation of a protein from brain using calcium-dependent affinity-based adsorption chromatography on phenothiazine-Sepharose conjugates. Annals of the New York Academy of Sciences. 356: 410-1. PMID 6940504 DOI: 10.1111/j.1749-6632.1980.tb29651.x |
0.488 |
|
| 1980 |
Van Eldik LJ, Piperno G, Watterson DM. Similarities and dissimilarities between calmodulin and a Chlamydomonas flagellar protein. Proceedings of the National Academy of Sciences of the United States of America. 77: 4779-83. PMID 6254039 |
0.516 |
|
| 1980 |
Watterson DM, Iverson DB, Van Eldik LJ. Rapid separation and quantitation of 3',5'-cyclic nucleotides and 5'-nucleotides in phosphodiesterase reaction mixtures using high-performance liquid chromatography. Journal of Biochemical and Biophysical Methods. 2: 139-46. PMID 6252261 DOI: 10.1016/0165-022X(80)90021-4 |
0.425 |
|
| 1980 |
Van Eldik LJ, Piperno G, Watterson DM. Comparative biochemistry of calmodulins and calmodulin-like proteins. Annals of the New York Academy of Sciences. 356: 36-42. PMID 6112948 DOI: 10.1111/j.1749-6632.1980.tb29597.x |
0.507 |
|
| 1980 |
Van Eldik LJ, Grossman AR, Iverson DB, Watterson DM. Isolation and characterization of calmodulin from spinach leaves and in vitro translation mixtures Proceedings of the National Academy of Sciences of the United States of America. 77: 1912-1916. DOI: 10.1073/Pnas.77.4.1912 |
0.513 |
|
| 1979 |
Van Eldik LJ, Watterson DM. Characterization of a calcium-modulated protein from transformed chicken fibroblasts. The Journal of Biological Chemistry. 254: 10250-5. PMID 226538 |
0.502 |
|
| 1976 |
Watterson DM, Van Eldik LJ, Smith RE, Vanaman TC. Calcium-dependent regulatory protein of cyclic nucleotide metabolism in normal and transformed chicken embryo fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 73: 2711-5. PMID 183206 DOI: 10.1073/Pnas.73.8.2711 |
0.494 |
|
| Show low-probability matches. |