| Year |
Citation |
Score |
| 2019 |
Hsu TI, Chen YJ, Hung CY, Wang YC, Lin SJ, Su WC, Lai MD, Kim SY, Wang Q, Qian K, Goto M, Zhao Y, Kashiwada Y, Lee KH, Chang WC, et al. Correction: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy. Oncotarget. 10: 6536-6537. PMID 31741716 DOI: 10.18632/Oncotarget.27297 |
0.431 |
|
| 2015 |
Hsu TI, Chen YJ, Hung CY, Wang YC, Lin SJ, Su WC, Lai MD, Kim SY, Wang Q, Qian K, Goto M, Zhao Y, Kashiwada Y, Lee KH, Chang WC, et al. A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy. Oncotarget. 6: 13671-87. PMID 25909174 DOI: 10.18632/Oncotarget.3701 |
0.459 |
|
| 2015 |
Liu YQ, Li WQ, Morris-Natschke SL, Qian K, Yang L, Zhu GX, Wu XB, Chen AL, Zhang SY, Nan X, Lee KH. Perspectives on Biologically Active Camptothecin Derivatives. Medicinal Research Reviews. 35: 753-89. PMID 25808858 DOI: 10.1002/Med.21342 |
0.545 |
|
| 2015 |
Liu YQ, Tian J, Qian K, Zhao XB, Morris-Natschke SL, Yang L, Nan X, Tian X, Lee KH. Recent progress on C-4-modified podophyllotoxin analogs as potent antitumor agents. Medicinal Research Reviews. 35: 1-62. PMID 24827545 DOI: 10.1002/Med.21319 |
0.572 |
|
| 2014 |
Wang MJ, Liu YQ, Chang LC, Wang CY, Zhao YL, Zhao XB, Qian K, Nan X, Yang L, Yang XM, Hung HY, Yang JS, Kuo DH, Goto M, Morris-Natschke SL, et al. Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents. Journal of Medicinal Chemistry. 57: 6008-18. PMID 25003995 DOI: 10.1021/Jm5003588 |
0.653 |
|
| 2014 |
Wu ZY, Liu N, Qin B, Huang L, Yu F, Qian K, Morris-Natschke SL, Jiang S, Chen CH, Lee KH, Xie L. Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS. Chemmedchem. 9: 1546-55. PMID 24895029 DOI: 10.1002/Cmdc.201400075 |
0.608 |
|
| 2014 |
Wang XF, Guan F, Ohkoshi E, Guo W, Wang L, Zhu DQ, Wang SB, Wang LT, Hamel E, Yang D, Li L, Qian K, Morris-Natschke SL, Yuan S, Lee KH, et al. Optimization of 4-(N-cycloamino)phenylquinazolines as a novel class of tubulin-polymerization inhibitors targeting the colchicine site. Journal of Medicinal Chemistry. 57: 1390-402. PMID 24502232 DOI: 10.1021/Jm4016526 |
0.568 |
|
| 2014 |
Hung HY, Nakagawa-Goto K, Tokuda H, Iida A, Suzuki N, Bori ID, Qian K, Lee KH. A-ring modified betulinic acid derivatives as potent cancer preventive agents. Bioorganic & Medicinal Chemistry Letters. 24: 1005-8. PMID 24411124 DOI: 10.1016/J.Bmcl.2013.12.041 |
0.7 |
|
| 2014 |
Yang L, Zhao Y, Zhao C, Li H, Wang M, Morris-Natschke SL, Qian K, Lee K, Liu Y. Design, synthesis, crystal structure, bioactivity, and molecular docking studies of novel sulfonylamidine-derived neonicotinoid analogs Medicinal Chemistry Research. 23: 5043-5057. DOI: 10.1007/S00044-014-1046-5 |
0.382 |
|
| 2013 |
Wang XF, Wang SB, Ohkoshi E, Wang LT, Hamel E, Qian K, Morris-Natschke SL, Lee KH, Xie L. N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines: a novel class of antitumor agents targeting the colchicine site on tubulin. European Journal of Medicinal Chemistry. 67: 196-207. PMID 23867604 DOI: 10.1016/J.Ejmech.2013.06.041 |
0.602 |
|
| 2013 |
Asada Y, Sukemori A, Watanabe T, Malla KJ, Yoshikawa T, Li W, Kuang X, Koike K, Chen CH, Akiyama T, Qian K, Nakagawa-Goto K, Morris-Natschke SL, Lu Y, Lee KH. Isolation, structure determination, and anti-HIV evaluation of tigliane-type diterpenes and biflavonoid from Stellera chamaejasme. Journal of Natural Products. 76: 852-7. PMID 23611151 DOI: 10.1021/Np300815T |
0.645 |
|
| 2013 |
Li WQ, Wang XL, Qian K, Liu YQ, Wang CY, Yang L, Tian J, Morris-Natschke SL, Zhou XW, Lee KH. Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives. Bioorganic & Medicinal Chemistry. 21: 2363-9. PMID 23490151 DOI: 10.1016/J.Bmc.2013.01.069 |
0.594 |
|
| 2013 |
Dang Z, Ho P, Zhu L, Qian K, Lee KH, Huang L, Chen CH. New betulinic acid derivatives for bevirimat-resistant human immunodeficiency virus type-1. Journal of Medicinal Chemistry. 56: 2029-37. PMID 23379607 DOI: 10.1021/Jm3016969 |
0.609 |
|
| 2012 |
Lee KH, Morris-Natschke S, Qian K, Dong Y, Yang X, Zhou T, Belding E, Wu SF, Wada K, Akiyama T. Recent Progress of Research on Herbal Products Used in Traditional Chinese Medicine: the Herbs belonging to The Divine Husbandman's Herbal Foundation Canon ( Shén Nóng Běn Cǎo Jīng). Journal of Traditional and Complementary Medicine. 2: 6-26. PMID 24716110 DOI: 10.1016/S2225-4110(16)30066-9 |
0.573 |
|
| 2012 |
Guo H, Zhuang X, Qian K, Sun L, Wang X, Li H, Lee K, Xie L. Prodrug design, synthesis and pharmacokinetic evaluation of (3' R, 4' R)-3-hydroxymethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone. Acta Pharmaceutica Sinica. B. 2: 213-219. PMID 23687633 DOI: 10.1016/J.Apsb.2012.02.008 |
0.599 |
|
| 2012 |
Dang Z, Jung K, Qian K, Lee KH, Huang L, Chen CH. Synthesis of Lithocholic Acid Derivatives as Proteasome Regulators. Acs Medicinal Chemistry Letters. 3: 925-930. PMID 23330053 DOI: 10.1021/Ml3001962 |
0.531 |
|
| 2012 |
Liu Y, Qian K, Wang CY, Chen CH, Yang X, Lee KH. Synthesis and biological evaluation of novel spin labeled 18β-glycyrrhetinic acid derivatives. Bioorganic & Medicinal Chemistry Letters. 22: 7530-3. PMID 23122524 DOI: 10.1016/J.Bmcl.2012.10.041 |
0.553 |
|
| 2012 |
Qian K, Bori ID, Chen CH, Huang L, Lee KH. Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors. Journal of Medicinal Chemistry. 55: 8128-36. PMID 22978745 DOI: 10.1021/Jm301040S |
0.658 |
|
| 2012 |
Wang XF, Tian XT, Ohkoshi E, Qin B, Liu YN, Wu PC, Hour MJ, Hung HY, Qian K, Huang R, Bastow KF, Janzen WP, Jin J, Morris-Natschke SL, Lee KH, et al. Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents. Bioorganic & Medicinal Chemistry Letters. 22: 6224-8. PMID 22932313 DOI: 10.1016/J.Bmcl.2012.08.014 |
0.692 |
|
| 2012 |
Sun LQ, Zhu L, Qian K, Qin B, Huang L, Chen CH, Lee KH, Xie L. Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates. Journal of Medicinal Chemistry. 55: 7219-29. PMID 22856541 DOI: 10.1021/Jm3007678 |
0.608 |
|
| 2012 |
Dang Z, Qian K, Ho P, Zhu L, Lee KH, Huang L, Chen CH. Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants. Bioorganic & Medicinal Chemistry Letters. 22: 5190-4. PMID 22818973 DOI: 10.1016/J.Bmcl.2012.06.080 |
0.594 |
|
| 2012 |
Bori ID, Hung HY, Qian K, Chen CH, Morris-Natschke SL, Lee KH. Anti-AIDS agents 88. Anti-HIV conjugates of betulin and betulinic acid with AZT prepared via click chemistry. Tetrahedron Letters. 53: 1987-1989. PMID 22711941 DOI: 10.1016/J.Tetlet.2012.02.022 |
0.728 |
|
| 2012 |
Hung HY, Qian K, Morris-Natschke SL, Hsu CS, Lee KH. Recent discovery of plant-derived anti-diabetic natural products. Natural Product Reports. 29: 580-606. PMID 22491825 DOI: 10.1039/C2Np00074A |
0.593 |
|
| 2012 |
Sun LQ, Qin B, Huang L, Qian K, Chen CH, Lee KH, Xie L. Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 2376-9. PMID 22406117 DOI: 10.1016/J.Bmcl.2012.02.055 |
0.608 |
|
| 2012 |
Chen Y, Liu HR, Liu HS, Cheng M, Xia P, Qian K, Wu PC, Lai CY, Xia Y, Yang ZY, Morris-Natschke SL, Lee KH. Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents. European Journal of Medicinal Chemistry. 49: 74-85. PMID 22265685 DOI: 10.1016/J.Ejmech.2011.12.025 |
0.619 |
|
| 2012 |
Vijaya Bhaskar Reddy M, Shen YC, Ohkoshi E, Bastow KF, Qian K, Lee KH, Wu TS. Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents. European Journal of Medicinal Chemistry. 47: 97-103. PMID 22115618 DOI: 10.1016/J.Ejmech.2011.10.026 |
0.619 |
|
| 2011 |
Vijaya Bhaskar Reddy M, Tsai WJ, Qian K, Lee KH, Wu TS. Structure-activity relationships of chalcone analogs as potential inhibitors of ADP- and collagen-induced platelet aggregation. Bioorganic & Medicinal Chemistry. 19: 7711-9. PMID 22055718 DOI: 10.1016/J.Bmc.2011.08.004 |
0.51 |
|
| 2011 |
Liu HS, Xu SQ, Cheng M, Chen Y, Xia P, Qian K, Xia Y, Yang ZY, Chen CH, Morris-Natschke SL, Lee KH. Anti-AIDS agents 87. New bio-isosteric dicamphanoyl-dihydropyranochromone (DCP) and dicamphanoyl-khellactone (DCK) analogues with potent anti-HIV activity. Bioorganic & Medicinal Chemistry Letters. 21: 5831-4. PMID 21871800 DOI: 10.1016/J.Bmcl.2011.07.105 |
0.616 |
|
| 2011 |
Chen Y, Cheng M, Liu FQ, Xia P, Qian K, Yu D, Xia Y, Yang ZY, Chen CH, Morris-Natschke SL, Lee KH. Anti-AIDS agents 86. Synthesis and anti-HIV evaluation of 2',3'-seco-3'-nor DCP and DCK analogues. European Journal of Medicinal Chemistry. 46: 4924-36. PMID 21864952 DOI: 10.1016/J.Ejmech.2011.07.051 |
0.745 |
|
| 2011 |
Qian K, Kim SY, Hung HY, Huang L, Chen CH, Lee KH. New betulinic acid derivatives as potent proteasome inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 5944-7. PMID 21856154 DOI: 10.1016/J.Bmcl.2011.07.072 |
0.692 |
|
| 2011 |
Wang Q, Hu W, Wang S, Pan Z, Tao L, Guo X, Qian K, Chen CH, Lee KH, Chang J. Synthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents. European Journal of Medicinal Chemistry. 46: 4178-83. PMID 21745701 DOI: 10.1016/J.Ejmech.2011.06.020 |
0.649 |
|
| 2011 |
Asada Y, Sukemori A, Watanabe T, Malla KJ, Yoshikawa T, Li W, Koike K, Chen CH, Akiyama T, Qian K, Nakagawa-Goto K, Morris-Natschke SL, Lee KH. Stelleralides A-C, novel potent anti-HIV daphnane-type diterpenoids from Stellera chamaejasme L. Organic Letters. 13: 2904-7. PMID 21561135 DOI: 10.1021/Ol200889S |
0.646 |
|
| 2011 |
Chan HH, Hwang TL, Reddy MV, Li DT, Qian K, Bastow KF, Lee KH, Wu TS. Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds. Journal of Natural Products. 74: 796-802. PMID 21417387 DOI: 10.1021/Np100851S |
0.53 |
|
| 2011 |
Reddy MV, Shen YC, Yang JS, Hwang TL, Bastow KF, Qian K, Lee KH, Wu TS. New bichalcone analogs as NF-κB inhibitors and as cytotoxic agents inducing Fas/CD95-dependent apoptosis. Bioorganic & Medicinal Chemistry. 19: 1895-906. PMID 21377368 DOI: 10.1016/J.Bmc.2011.02.004 |
0.579 |
|
| 2011 |
Yang ML, Kuo PC, Hwang TL, Chiou WF, Qian K, Lai CY, Lee KH, Wu TS. Synthesis, in vitro anti-inflammatory and cytotoxic evaluation, and mechanism of action studies of 1-benzoyl-β-carboline and 1-benzoyl-3-carboxy-β-carboline derivatives. Bioorganic & Medicinal Chemistry. 19: 1674-82. PMID 21316977 DOI: 10.1016/J.Bmc.2011.01.034 |
0.582 |
|
| 2011 |
Zhang P, Xu L, Qian K, Liu J, Zhang L, Lee KH, Sun H. Efficient synthesis and biological evaluation of epiceanothic acid and related compounds. Bioorganic & Medicinal Chemistry Letters. 21: 338-41. PMID 21123066 DOI: 10.1016/J.Bmcl.2010.11.004 |
0.661 |
|
| 2011 |
Shi LS, Chao CH, Shen DY, Chan HH, Chen CH, Liao YR, Wu SJ, Leu YL, Shen YC, Kuo YH, Lee EJ, Qian K, Wu TS, Lee KH. Biologically active constituents from the fruiting body of Taiwanofungus camphoratus. Bioorganic & Medicinal Chemistry. 19: 677-83. PMID 21115251 DOI: 10.1016/J.Bmc.2010.10.032 |
0.588 |
|
| 2011 |
Wang Q, Hu W, Wang S, Pan Z, Tao L, Guo X, Qian K, Chen C, Lee K, Chang J. ChemInform Abstract: Synthesis of New 2′-Deoxy-2′-fluoro-4′-azido Nucleoside Analogues as Potent anti-HIV Agents. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201204187 |
0.369 |
|
| 2010 |
Wu SJ, Leu YL, Chen CH, Chao CH, Shen DY, Chan HH, Lee EJ, Wu TS, Wang YH, Shen YC, Qian K, Bastow KF, Lee KH. Camphoratins A-J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus. Journal of Natural Products. 73: 1756-62. PMID 21028898 DOI: 10.1021/Np1002143 |
0.608 |
|
| 2010 |
Chou LC, Tsai MT, Hsu MH, Wang SH, Way TD, Huang CH, Lin HY, Qian K, Dong Y, Lee KH, Huang LJ, Kuo SC. Design, synthesis, and preclinical evaluation of new 5,6- (or 6,7-) disubstituted-2-(fluorophenyl)quinolin-4-one derivatives as potent antitumor agents. Journal of Medicinal Chemistry. 53: 8047-58. PMID 20973552 DOI: 10.1021/Jm100780C |
0.648 |
|
| 2010 |
Xu SQ, Yan X, Chen Y, Xia P, Qian K, Yu D, Xia Y, Yang ZY, Morris-Natschke SL, Lee KH. Anti-AIDS agents 84. Synthesis and anti-human immunodeficiency virus (HIV) activity of 2'-monomethyl-4-methyl- and 1'-thia-4-methyl-(3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogs. Bioorganic & Medicinal Chemistry. 18: 7203-11. PMID 20846868 DOI: 10.1016/J.Bmc.2010.08.031 |
0.712 |
|
| 2010 |
Xiong J, Kashiwada Y, Chen CH, Qian K, Morris-Natschke SL, Lee KH, Takaishi Y. Conjugates of betulin derivatives with AZT as potent anti-HIV agents. Bioorganic & Medicinal Chemistry. 18: 6451-69. PMID 20673723 DOI: 10.1016/J.Bmc.2010.06.092 |
0.611 |
|
| 2010 |
Wang Q, Li Y, Song C, Qian K, Chen CH, Lee KH, Chang J. Synthesis and anti-HIV activity of 2'-deoxy-2'-fluoro-4'-C-ethynyl nucleoside analogs. Bioorganic & Medicinal Chemistry Letters. 20: 4053-6. PMID 20542430 DOI: 10.1016/J.Bmcl.2010.05.090 |
0.654 |
|
| 2010 |
Tang J, Qian K, Zhang BN, Chen Y, Xia P, Yu D, Xia Y, Yang ZY, Chen CH, Morris-Natschke SL, Lee KH. Anti-AIDS agents 82: synthesis of seco-(3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives as novel anti-HIV agents. Bioorganic & Medicinal Chemistry. 18: 4363-73. PMID 20537902 DOI: 10.1016/J.Bmc.2010.04.089 |
0.75 |
|
| 2010 |
Qin B, Jiang X, Lu H, Tian X, Barbault F, Huang L, Qian K, Chen CH, Huang R, Jiang S, Lee KH, Xie L. Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors. Journal of Medicinal Chemistry. 53: 4906-16. PMID 20527972 DOI: 10.1021/Jm1002952 |
0.589 |
|
| 2010 |
Qian K, Kuo RY, Chen CH, Huang L, Morris-Natschke SL, Lee KH. Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors. Journal of Medicinal Chemistry. 53: 3133-41. PMID 20329730 DOI: 10.1021/Jm901782M |
0.643 |
|
| 2010 |
Liu J, Zhao M, Qian K, Zhang X, Lee KH, Wu J, Liu YN, Peng S. Benzyl 1,2,3,5,11,11a-hexahydro-3,3-dimethyl-1-oxo-6H-imidazo[3',4':1,2]pyridin[3,4-b]indole-2-substituted acetates: One-pot-preparation, anti-tumor activity, docking toward DNA and 3D QSAR analysis. Bioorganic & Medicinal Chemistry. 18: 1910-7. PMID 20171109 DOI: 10.1016/J.Bmc.2010.01.038 |
0.502 |
|
| 2010 |
Chou LC, Chen CT, Lee JC, Way TD, Huang CH, Huang SM, Teng CM, Yamori T, Wu TS, Sun CM, Chien DS, Qian K, Morris-Natschke SL, Lee KH, Huang LJ, et al. Synthesis and preclinical evaluations of 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one monosodium phosphate (CHM-1-P-Na) as a potent antitumor agent. Journal of Medicinal Chemistry. 53: 1616-26. PMID 20102207 DOI: 10.1021/Jm901292J |
0.564 |
|
| 2010 |
Li SL, Song JZ, Qiao CF, Zhou Y, Qian K, Lee KH, Xu HX. A novel strategy to rapidly explore potential chemical markers for the discrimination between raw and processed Radix Rehmanniae by UHPLC-TOFMS with multivariate statistical analysis. Journal of Pharmaceutical and Biomedical Analysis. 51: 812-23. PMID 19879709 DOI: 10.1016/j.jpba.2009.10.002 |
0.361 |
|
| 2010 |
Wu S, Chan H, Hwang T, Qian K, Morris-Natschke S, Lee K, Wu T. Salviatalin A and salvitrijudin A, two diterpenes with novel skeletons from roots of Salvia digitaloides and anti-inflammatory evaluation Tetrahedron Letters. 51: 4287-4290. DOI: 10.1016/J.Tetlet.2010.06.048 |
0.366 |
|
| 2010 |
Wang Q, Li Y, Song C, Qian K, Chen C, Lee K, Chang J. ChemInform Abstract: Synthesis and anti-HIV Activity of 2′-Deoxy-2′-fluoro-4′-C-ethynyl Nucleoside Analogues. Cheminform. 41: no-no. DOI: 10.1002/chin.201049203 |
0.352 |
|
| 2010 |
Kuo R, Qian K, Morris-Natschke SL, Lee K. ChemInform Abstract: Anitumor Agents. Part 267. Anti-AIDS-Agents. Part 77. Plant-Derived Triterpenoids and Analogues as Antitumor and anti-HIV Agents Cheminform. 41. DOI: 10.1002/chin.201002265 |
0.313 |
|
| 2009 |
Kuo RY, Qian K, Morris-Natschke SL, Lee KH. Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents. Natural Product Reports. 26: 1321-44. PMID 19779642 DOI: 10.1039/B810774M |
0.621 |
|
| 2009 |
Chang YH, Hsu MH, Wang SH, Huang LJ, Qian K, Morris-Natschke SL, Hamel E, Kuo SC, Lee KH. Design and synthesis of 2-(3-benzo[b]thienyl)-6,7-methylenedioxyquinolin-4-one analogues as potent antitumor agents that inhibit tubulin assembly. Journal of Medicinal Chemistry. 52: 4883-91. PMID 19719238 DOI: 10.1021/Jm900456W |
0.597 |
|
| 2009 |
Huang F, Zhao M, Zhang X, Wang C, Qian K, Kuo RY, Morris-Natschke S, Lee KH, Peng S. Synthesis, DNA intercalation and 3D QSAR analysis of cis-2,4,5-trisubstituted-1,3-dithiolanes as a novel class of antitumor agents. Bioorganic & Medicinal Chemistry. 17: 6085-95. PMID 19631550 DOI: 10.1016/J.Bmc.2009.06.011 |
0.541 |
|
| 2009 |
Wu J, Zhao M, Qian K, Lee KH, Morris-Natschke S, Peng S. Novel N-(3-carboxyl-9-benzyl-beta-carboline-1-yl)ethylamino acids: synthesis, anti-tumor evaluation, intercalating determination, 3D QSAR analysis and docking investigation. European Journal of Medicinal Chemistry. 44: 4153-61. PMID 19535177 DOI: 10.1016/J.Ejmech.2009.05.006 |
0.557 |
|
| 2009 |
Dang Z, Lai W, Qian K, Ho P, Lee KH, Chen CH, Huang L. Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors. Journal of Medicinal Chemistry. 52: 7887-91. PMID 19526990 DOI: 10.1021/Jm9004253 |
0.607 |
|
| 2009 |
Qian K, Yu D, Chen CH, Huang L, Morris-Natschke SL, Nitz TJ, Salzwedel K, Reddick M, Allaway GP, Lee KH. Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents. Journal of Medicinal Chemistry. 52: 3248-58. PMID 19388685 DOI: 10.1021/Jm900136J |
0.742 |
|
| 2009 |
Qian K, Morris-Natschke SL, Lee KH. HIV entry inhibitors and their potential in HIV therapy. Medicinal Research Reviews. 29: 369-93. PMID 18720513 DOI: 10.1002/Med.20138 |
0.569 |
|
| 2008 |
Xie L, Guo HF, Lu H, Zhuang XM, Zhang AM, Wu G, Ruan JX, Zhou T, Yu D, Qian K, Lee KH, Jiang S. Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK). Journal of Medicinal Chemistry. 51: 7689-96. PMID 19053755 DOI: 10.1021/Jm8003009 |
0.711 |
|
| 2008 |
Huang L, Yu D, Ho P, Qian K, Lee KH, Chen CH. Synthesis and proteasome inhibition of glycyrrhetinic acid derivatives. Bioorganic & Medicinal Chemistry. 16: 6696-701. PMID 18562200 DOI: 10.1016/J.Bmc.2008.05.078 |
0.654 |
|
| 2008 |
Chen Y, Cui G, Zhao M, Wang C, Qian K, Morris-Natschke S, Lee KH, Peng S. Synthesis, nano-scale assembly, and in vivo anti-thrombotic activity of novel short peptides containing L-Arg and L-Asp or L-Glu. Bioorganic & Medicinal Chemistry. 16: 5914-25. PMID 18495483 DOI: 10.1016/J.Bmc.2008.04.064 |
0.427 |
|
| 2008 |
Lin AS, Qian K, Usami Y, Lin L, Itokawa H, Hsu C, Morris-Natschke SL, Lee KH. 5-Hydroxymethyl-2-furfural, a clinical trials agent for sickle cell anemia, and its mono/di-glucosides from classically processed steamed Rehmanniae Radix. Journal of Natural Medicines. 62: 164-7. PMID 18404317 DOI: 10.1007/S11418-007-0206-Z |
0.467 |
|
| 2007 |
Qian K, Nakagawa-Goto K, Yu D, Morris-Natschke SL, Nitz TJ, Kilgore N, Allaway GP, Lee KH. Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives. Bioorganic & Medicinal Chemistry Letters. 17: 6553-7. PMID 17935987 DOI: 10.1016/J.Bmcl.2007.09.081 |
0.706 |
|
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