David L. Hacker - Publications

Affiliations: 
The University of Tennessee, Knoxville, TN, United States 
Area:
Microbiology Biology, Molecular Biology

10/113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2001 Lee SK, Dabney-Smith C, Hacker DL, Bruce BD. Membrane activity of the southern cowpea mosaic virus coat protein: the role of basic amino acids, helix-forming potential, and lipid composition. Virology. 291: 299-310. PMID 11878899 DOI: 10.1006/Viro.2001.1210  0.508
2001 Lee SK, Hacker DL. In vitro analysis of an RNA binding site within the N-terminal 30 amino acids of the southern cowpea mosaic virus coat protein. Virology. 286: 317-27. PMID 11485399 DOI: 10.1006/Viro.2001.0979  0.522
2000 Hacker DL, Fowler BC. Complementation of the host range restriction of southern cowpea mosaic virus in bean by southern bean mosaic virus. Virology. 266: 140-9. PMID 10612668 DOI: 10.1006/Viro.1999.0072  0.345
1998 Sivakumaran K, Fowler BC, Hacker DL. Identification of viral genes required for cell-to-cell movement of southern bean mosaic virus. Virology. 252: 376-86. PMID 9878617 DOI: 10.1006/Viro.1998.9489  0.434
1998 Sivakumaran K, Hacker DL. The 105-kDa polyprotein of southern bean mosaic virus is translated by scanning ribosomes. Virology. 246: 34-44. PMID 9656991 DOI: 10.1006/Viro.1998.9183  0.427
1997 Hacker DL, Sivakumaran K. Mapping and expression of southern bean mosaic virus genomic and subgenomic RNAs. Virology. 234: 317-27. PMID 9268164 DOI: 10.1006/Viro.1997.8667  0.456
1995 Bowen MD, Jackson AO, Bruns TD, Hacker DL, Hardy JL. Determination and comparative analysis of the small RNA genomic sequences of California encephalitis, Jamestown Canyon, Jerry Slough, Melao, Keystone and Trivittatus viruses (Bunyaviridae, genus Bunyavirus, California serogroup). The Journal of General Virology. 76: 559-72. PMID 7897347 DOI: 10.1099/0022-1317-76-3-559  0.382
1995 Hacker DL. Identification of a coat protein binding site on southern bean mosaic virus RNA. Virology. 207: 562-5. PMID 7886960 DOI: 10.1006/Viro.1995.1117  0.483
1992 Hacker DL, Petty IT, Wei N, Morris TJ. Turnip crinkle virus genes required for RNA replication and virus movement. Virology. 186: 1-8. PMID 1727594 DOI: 10.1016/0042-6822(92)90055-T  0.36
1992 Wei N, Hacker DL, Morris TJ. Characterization of an internal element in turnip crinkle virus RNA involved in both coat protein binding and replication. Virology. 190: 346-55. PMID 1529538 DOI: 10.1016/0042-6822(92)91221-F  0.413
Low-probability matches (unlikely to be authored by this person)
2019 Alpern D, Gardeux V, Russeil J, Mangeat B, Meireles-Filho ACA, Breysse R, Hacker D, Deplancke B. BRB-seq: ultra-affordable high-throughput transcriptomics enabled by bulk RNA barcoding and sequencing. Genome Biology. 20: 71. PMID 30999927 DOI: 10.1186/S13059-019-1671-X  0.285
2004 Hacker DL, Bertschinger M, Baldi L, Wurm FM. Reduction of adenovirus E1A mRNA by RNAi results in enhanced recombinant protein expression in transiently transfected HEK293 cells. Gene. 341: 227-34. PMID 15474305 DOI: 10.1016/j.gene.2004.06.054  0.241
2014 Shen X, Hacker DL, Baldi L, Wurm FM. Virus-free transient protein production in Sf9 cells. Journal of Biotechnology. 171: 61-70. PMID 24333123 DOI: 10.1016/j.jbiotec.2013.11.018  0.241
2008 Wulhfard S, Tissot S, Bouchet S, Cevey J, De Jesus M, Hacker DL, Wurm FM. Mild hypothermia improves transient gene expression yields several fold in Chinese hamster ovary cells. Biotechnology Progress. 24: 458-65. PMID 18220408 DOI: 10.1021/bp070286c  0.219
2020 Hacker DL, Ordóñez-Morán P. Large-Scale Production of Recombinant Noggin and R-Spondin1 Proteins Required for the Maintenance of Stem Cells in Intestinal Organoid Cultures. Methods in Molecular Biology (Clifton, N.J.). 2171: 171-184. PMID 32705641 DOI: 10.1007/978-1-0716-0747-3_10  0.217
2007 Baldi L, Hacker DL, Adam M, Wurm FM. Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives. Biotechnology Letters. 29: 677-84. PMID 17235486 DOI: 10.1007/s10529-006-9297-y  0.204
2015 Rajendra Y, Kiseljak D, Baldi L, Wurm FM, Hacker DL. Transcriptional and post-transcriptional limitations of high-yielding, PEI-mediated transient transfection with CHO and HEK-293E cells. Biotechnology Progress. 31: 541-9. PMID 25683738 DOI: 10.1002/btpr.2064  0.204
2005 Hacker DL, Derow E, Wurm FM. The CELO adenovirus Gam1 protein enhances transient and stable recombinant protein expression in Chinese hamster ovary cells. Journal of Biotechnology. 117: 21-9. PMID 15831244 DOI: 10.1016/j.jbiotec.2005.01.006  0.202
1989 Hacker DL, Friderici K, Fluck MM. A nonlethal mutation in large T antigen of polyomavirus which affects viral DNA synthesis Journal of Virology. 63: 776-781. PMID 2536103 DOI: 10.1128/Jvi.63.2.776-781.1989  0.2
2015 Shen X, Pitol AK, Bachmann V, Hacker DL, Baldi L, Wurm FM. A simple plasmid-based transient gene expression method using High Five cells. Journal of Biotechnology. 216: 67-75. PMID 26476358 DOI: 10.1016/j.jbiotec.2015.10.007  0.196
2015 Balasubramanian S, Matasci M, Kadlecova Z, Baldi L, Hacker DL, Wurm FM. Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools. Journal of Biotechnology. 200: 61-9. PMID 25758242 DOI: 10.1016/j.jbiotec.2015.03.001  0.175
2012 Baldi L, Hacker DL, Meerschman C, Wurm FM. Large-scale transfection of mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 801: 13-26. PMID 21987244 DOI: 10.1007/978-1-61779-352-3_2  0.175
2012 Kadlecova Z, Nallet S, Hacker DL, Baldi L, Klok HA, Wurm FM. Poly(ethyleneimine)-mediated large-scale transient gene expression: influence of molecular weight, polydispersity and N-propionyl groups. Macromolecular Bioscience. 12: 628-36. PMID 22411776 DOI: 10.1002/mabi.201100404  0.174
2006 Bertschinger M, Backliwal G, Schertenleib A, Jordan M, Hacker DL, Wurm FM. Disassembly of polyethylenimine-DNA particles in vitro: implications for polyethylenimine-mediated DNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 116: 96-104. PMID 17079047 DOI: 10.1016/j.jconrel.2006.09.006  0.172
2015 Waszak SM, Delaneau O, Gschwind AR, Kilpinen H, Raghav SK, Witwicki RM, Orioli A, Wiederkehr M, Panousis NI, Yurovsky A, Romano-Palumbo L, Planchon A, Bielser D, Padioleau I, Udin G, ... ... Hacker D, et al. Population Variation and Genetic Control of Modular Chromatin Architecture in Humans. Cell. 162: 1039-50. PMID 26300124 DOI: 10.1016/J.Cell.2015.08.001  0.171
2008 Backliwal G, Hildinger M, Kuettel I, Delegrange F, Hacker DL, Wurm FM. Valproic acid: a viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures. Biotechnology and Bioengineering. 101: 182-9. PMID 18454496 DOI: 10.1002/bit.21882  0.165
2007 Muller N, Derouazi M, Van Tilborgh F, Wulhfard S, Hacker DL, Jordan M, Wurm FM. Scalable transient gene expression in Chinese hamster ovary cells in instrumented and non-instrumented cultivation systems. Biotechnology Letters. 29: 703-11. PMID 17310326 DOI: 10.1007/s10529-006-9298-x  0.165
2009 Hacker DL, De Jesus M, Wurm FM. 25 years of recombinant proteins from reactor-grown cells - where do we go from here? Biotechnology Advances. 27: 1023-7. PMID 19463938 DOI: 10.1016/j.biotechadv.2009.05.008  0.164
2016 Hacker DL, Balasubramanian S. Recombinant protein production from stable mammalian cell lines and pools. Current Opinion in Structural Biology. 38: 129-136. PMID 27322762 DOI: 10.1016/j.sbi.2016.06.005  0.164
2011 Rajendra Y, Kiseljak D, Baldi L, Hacker DL, Wurm FM. Influence of glutamine on transient and stable recombinant protein production in CHO and HEK-293 cells. Bmc Proceedings. 5: P35. PMID 22373018 DOI: 10.1186/1753-6561-5-S8-P35  0.162
2011 Oberbek A, Matasci M, Hacker DL, Wurm FM. Generation of stable, high-producing CHO cell lines by lentiviral vector-mediated gene transfer in serum-free suspension culture. Biotechnology and Bioengineering. 108: 600-10. PMID 20967750 DOI: 10.1002/bit.22968  0.161
2010 Wulhfard S, Baldi L, Hacker DL, Wurm F. Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells. Journal of Biotechnology. 148: 128-32. PMID 20510314 DOI: 10.1016/j.jbiotec.2010.05.003  0.16
2008 Matasci M, Hacker DL, Baldi L, Wurm FM. Recombinant therapeutic protein production in cultivated mammalian cells: current status and future prospects. Drug Discovery Today. Technologies. 5: e37-42. PMID 24981089 DOI: 10.1016/j.ddtec.2008.12.003  0.159
2008 Chenuet S, Martinet D, Besuchet-Schmutz N, Wicht M, Jaccard N, Bon AC, Derouazi M, Hacker DL, Beckmann JS, Wurm FM. Calcium phosphate transfection generates mammalian recombinant cell lines with higher specific productivity than polyfection. Biotechnology and Bioengineering. 101: 937-45. PMID 18781700 DOI: 10.1002/bit.21972  0.159
2015 Rajendra Y, Balasubramanian S, Kiseljak D, Baldi L, Wurm FM, Hacker DL. Enhanced plasmid DNA utilization in transiently transfected CHO-DG44 cells in the presence of polar solvents. Biotechnology Progress. PMID 26260195 DOI: 10.1002/btpr.2152  0.158
2010 Zhang X, Garcia IF, Baldi L, Hacker DL, Wurm FM. Hyperosmolarity enhances transient recombinant protein yield in Chinese hamster ovary cells. Biotechnology Letters. 32: 1587-92. PMID 20574835 DOI: 10.1007/s10529-010-0331-8  0.158
2012 Kadlecova Z, Rajendra Y, Matasci M, Hacker D, Baldi L, Wurm FM, Klok HA. Hyperbranched polylysine: a versatile, biodegradable transfection agent for the production of recombinant proteins by transient gene expression and the transfection of primary cells. Macromolecular Bioscience. 12: 794-804. PMID 22496075 DOI: 10.1002/mabi.201100519  0.158
2016 Balasubramanian S, Hacker DL, Wurm FM. Multigene expression in stable CHO cell pools generated with the piggyBac transposon system. Biotechnology Progress. PMID 27302570 DOI: 10.1002/btpr.2319  0.157
2011 Rajendra Y, Kiseljak D, Baldi L, Hacker DL, Wurm FM. A simple high-yielding process for transient gene expression in CHO cells. Journal of Biotechnology. 153: 22-6. PMID 21392548 DOI: 10.1016/j.jbiotec.2011.03.001  0.156
2015 López AR, Dimitrov M, Gerber H, Braman V, Hacker DL, Wurm FM, Fraering PC. Production of active glycosylation-deficient γ-secretase complex for crystallization studies. Biotechnology and Bioengineering. PMID 26059427 DOI: 10.1002/bit.25675  0.151
2012 Rajendra Y, Kiseljak D, Baldi L, Hacker DL, Wurm FM. Reduced glutamine concentration improves protein production in growth-arrested CHO-DG44 and HEK-293E cells. Biotechnology Letters. 34: 619-26. PMID 22127760 DOI: 10.1007/s10529-011-0809-z  0.151
2020 Fenwick C, Croxatto A, Coste AT, Pojer F, André C, Pellaton C, Farina A, Campos J, Hacker D, Lau K, Bosch BJ, Gonseth Nussle S, Bochud M, D'Acremont V, Trono D, et al. Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies. Journal of Virology. PMID 33144321 DOI: 10.1128/JVI.01828-20  0.15
2011 Matasci M, Bachmann V, Baldi L, Hacker DL, De Jesus M, Wurm FM. Rapid recombinant protein production from pools of transposon-generated CHO cells. Bmc Proceedings. 5: P34. PMID 22373498 DOI: 10.1186/1753-6561-5-S8-P34  0.149
2015 Balasubramanian S, Rajendra Y, Baldi L, Hacker DL, Wurm FM. Comparison of three transposons for the generation of highly productive recombinant CHO cell pools and cell lines. Biotechnology and Bioengineering. PMID 26616356 DOI: 10.1002/bit.25888  0.148
2018 Hacker DL, Durrer L, Quinche S. CHO and HEK293 Cultivation and Transfection in Single-Use Orbitally Shaken Bioreactors. Methods in Molecular Biology (Clifton, N.J.). 1850: 123-131. PMID 30242684 DOI: 10.1007/978-1-4939-8730-6_9  0.148
2011 Tissot S, Oberbek A, Reclari M, Dreyer M, Hacker DL, Baldi L, Farhat M, Wurm FM. Efficient and reproducible mammalian cell bioprocesses without probes and controllers? New Biotechnology. 28: 382-90. PMID 21338722 DOI: 10.1016/j.nbt.2011.02.004  0.145
2013 Hacker DL, Kiseljak D, Rajendra Y, Thurnheer S, Baldi L, Wurm FM. Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells. Protein Expression and Purification. 92: 67-76. PMID 24021764 DOI: 10.1016/j.pep.2013.09.001  0.145
2007 Stettler M, Zhang X, Hacker DL, De Jesus M, Wurm FM. Novel orbital shake bioreactors for transient production of CHO derived IgGs. Biotechnology Progress. 23: 1340-6. PMID 17914862 DOI: 10.1021/bp070219i  0.145
2005 Hunt L, Hacker DL, Grosjean F, De Jesus M, Uebersax L, Jordan M, Wurm FM. Low-temperature pausing of cultivated mammalian cells. Biotechnology and Bioengineering. 89: 157-63. PMID 15584025 DOI: 10.1002/bit.20320  0.144
2009 Nallet S, Amacker M, Westerfeld N, Baldi L, König I, Hacker DL, Zaborosch C, Zurbriggen R, Wurm FM. Respiratory syncytial virus subunit vaccine based on a recombinant fusion protein expressed transiently in mammalian cells. Vaccine. 27: 6415-9. PMID 19559121 DOI: 10.1016/j.vaccine.2009.06.019  0.144
2011 Matasci M, Baldi L, Hacker DL, Wurm FM. The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability. Biotechnology and Bioengineering. 108: 2141-50. PMID 21495018 DOI: 10.1002/bit.23167  0.144
2016 Monteil DT, Juvet V, Paz J, Moniatte M, Baldi L, Hacker DL, Wurm FM. A comparison of orbitally-shaken and stirred-tank bioreactors: pH modulation and bioreactor type affect CHO cell growth and protein glycosylation. Biotechnology Progress. PMID 27453130 DOI: 10.1002/btpr.2328  0.144
2009 Chenuet S, Derouazi M, Hacker D, Wurm F. DNA delivery by microinjection for the generation of recombinant mammalian cell lines. Methods in Molecular Biology (Clifton, N.J.). 518: 99-112. PMID 19085129 DOI: 10.1007/978-1-59745-202-1_8  0.143
2011 Xie Q, Michel PO, Baldi L, Hacker DL, Zhang X, Wurm FM. TubeSpin bioreactor 50 for the high-density cultivation of Sf-9 insect cells in suspension. Biotechnology Letters. 33: 897-902. PMID 21267765 DOI: 10.1007/s10529-011-0527-6  0.143
2008 Bertschinger M, Schertenleib A, Cevey J, Hacker DL, Wurm FM. The kinetics of polyethylenimine-mediated transfection in suspension cultures of Chinese hamster ovary cells. Molecular Biotechnology. 40: 136-43. PMID 18543131 DOI: 10.1007/s12033-008-9069-0  0.138
2021 Lainšček D, Fink T, Forstnerič V, Hafner-Bratkovič I, Orehek S, Strmšek Ž, Manček-Keber M, Pečan P, Esih H, Malenšek Š, Aupič J, Dekleva P, Plaper T, Vidmar S, Kadunc L, ... ... Hacker D, et al. A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response. Vaccines. 9. PMID 33925446 DOI: 10.3390/vaccines9050431  0.136
2019 Delaneau O, Zazhytska M, Borel C, Giannuzzi G, Rey G, Howald C, Kumar S, Ongen H, Popadin K, Marbach D, Ambrosini G, Bielser D, Hacker D, Romano L, Ribaux P, et al. Chromatin three-dimensional interactions mediate genetic effects on gene expression. Science (New York, N.Y.). 364. PMID 31048460 DOI: 10.1126/Science.Aat8266  0.129
2006 Derouazi M, Martinet D, Besuchet Schmutz N, Flaction R, Wicht M, Bertschinger M, Hacker DL, Beckmann JS, Wurm FM. Genetic characterization of CHO production host DG44 and derivative recombinant cell lines Biochemical and Biophysical Research Communications. 340: 1069-1077. PMID 16403443 DOI: 10.1016/j.bbrc.2005.12.111  0.126
2017 Rajendra Y, Balasubramanian S, Hacker DL. Large-Scale Transient Transfection of Chinese Hamster Ovary Cells in Suspension. Methods in Molecular Biology (Clifton, N.J.). 1603: 45-55. PMID 28493122 DOI: 10.1007/978-1-4939-6972-2_3  0.125
2011 Shen X, Michel PO, Xie Q, Hacker DL, Wurm FM. Transient transfection of insect Sf-9 cells in TubeSpin(®) bioreactor 50 tubes. Bmc Proceedings. 5: P37. PMID 22373074 DOI: 10.1186/1753-6561-5-S8-P37  0.124
2012 Rajendra Y, Kiseljak D, Manoli S, Baldi L, Hacker DL, Wurm FM. Role of non-specific DNA in reducing coding DNA requirement for transient gene expression with CHO and HEK-293E cells. Biotechnology and Bioengineering. 109: 2271-8. PMID 22422519 DOI: 10.1002/bit.24494  0.124
2013 Alattia JR, Matasci M, Dimitrov M, Aeschbach L, Balasubramanian S, Hacker DL, Wurm FM, Fraering PC. Highly efficient production of the Alzheimer's γ-secretase integral membrane protease complex by a multi-gene stable integration approach. Biotechnology and Bioengineering. 110: 1995-2005. PMID 23359429 DOI: 10.1002/bit.24851  0.123
2009 Zhang X, Stettler M, De Sanctis D, Perrone M, Parolini N, Discacciati M, De Jesus M, Hacker D, Quarteroni A, Wurm F. Use of orbital shaken disposable bioreactors for mammalian cell cultures from the milliliter-scale to the 1,000-liter scale. Advances in Biochemical Engineering/Biotechnology. 115: 33-53. PMID 19499209 DOI: 10.1007/10_2008_18  0.121
2005 Muller N, Girard P, Hacker DL, Jordan M, Wurm FM. Orbital shaker technology for the cultivation of mammalian cells in suspension. Biotechnology and Bioengineering. 89: 400-6. PMID 15619325 DOI: 10.1002/bit.20358  0.112
2011 Balasubramanian S, Matasci M, Baldi L, Hacker DL, Wurm FM. Transposon mediated co-integration and co-expression of transgenes in CHO-DG44 cells. Bmc Proceedings. 5: P32. PMID 22373439 DOI: 10.1186/1753-6561-5-S8-P32  0.111
2013 Kilpinen H, Waszak SM, Gschwind AR, Raghav SK, Witwicki RM, Orioli A, Migliavacca E, Wiederkehr M, Gutierrez-Arcelus M, Panousis NI, Yurovsky A, Lappalainen T, Romano-Palumbo L, Planchon A, Bielser D, ... ... Hacker D, et al. Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. Science (New York, N.Y.). 342: 744-7. PMID 24136355 DOI: 10.1126/Science.1242463  0.109
2017 Shen X, Dojcinovic D, Baldi L, Hacker DL, Luescher IF, Wurm FM. Improved process conditions for increasing expression of MHC class II protein from a stable Drosophila S2 cell line. Biotechnology Letters. PMID 28993910 DOI: 10.1007/s10529-017-2440-0  0.108
2017 Lee RFS, Chernobrovkin A, Rutishauser D, Allardyce CS, Hacker D, Johnsson K, Zubarev RA, Dyson PJ. Expression proteomics study to determine metallodrug targets and optimal drug combinations. Scientific Reports. 7: 1590. PMID 28484215 DOI: 10.1038/S41598-017-01643-1  0.108
2011 Pereira J, Rajendra Y, Baldi L, Hacker DL, Wurm FM. Transient gene expression with CHO cells in conditioned medium: a study using TubeSpin(®) bioreactors. Bmc Proceedings. 5: P38. PMID 22373096 DOI: 10.1186/1753-6561-5-S8-P38  0.107
2016 Monteil DT, Shen X, Tontodonati G, Baldi L, Hacker DL, Wurm FM. Disposable orbitally-shaken TubeSpin bioreactor 600 for Sf9 cell cultivation in suspension. Analytical Biochemistry. PMID 27130502 DOI: 10.1016/j.ab.2016.04.009  0.106
2012 Michel PO, Degen C, Hubert M, Baldi L, Hacker DL, Wurm FM. A NanoDrop-based method for rapid determination of viability decline in suspension cultures of animal cells. Analytical Biochemistry. 430: 138-40. PMID 22960013 DOI: 10.1016/j.ab.2012.08.028  0.104
1989 Hacker DL, Fluck MM. Viral DNA synthesis in nonpermissive rat F-111 cells and its role in neoplastic transformation by polyomavirus Molecular and Cellular Biology. 9: 648-658. PMID 2540424  0.1
2013 Tissot S, Michel P, Douet C, Grezet S, Baldi L, Hacker D, Wurm F. Helical-Track Bioreactors for Bacterial, Mammalian and Insect Cell Cultures Processes. 1: 3-11. DOI: 10.3390/PR1010003  0.098
2012 Kadlecova Z, Baldi L, Hacker D, Wurm FM, Klok HA. Comparative study on the in vitro cytotoxicity of linear, dendritic, and hyperbranched polylysine analogues. Biomacromolecules. 13: 3127-37. PMID 22931162 DOI: 10.1021/bm300930j  0.098
2006 Stettler M, Jaccard N, Hacker D, De Jesus M, Wurm FM, Jordan M. New disposable tubes for rapid and precise biomass assessment for suspension cultures of mammalian cells. Biotechnology and Bioengineering. 95: 1228-33. PMID 16865737 DOI: 10.1002/bit.21071  0.096
2023 Emmenegger M, De Cecco E, Lamparter D, Jacquat RPB, Riou J, Menges D, Ballouz T, Ebner D, Schneider MM, Morales IC, Doğançay B, Guo J, Wiedmer A, Domange J, Imeri M, ... ... Hacker D, et al. Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region. Iscience. 105928. PMID 36619367 DOI: 10.1016/j.isci.2023.105928  0.096
2013 Kadlecova Z, Rajendra Y, Matasci M, Baldi L, Hacker DL, Wurm FM, Klok HA. DNA delivery with hyperbranched polylysine: a comparative study with linear and dendritic polylysine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 169: 276-88. PMID 23379996 DOI: 10.1016/j.jconrel.2013.01.019  0.095
2006 Grosjean F, Bertschinger M, Hacker DL, Wurm FM. Multiple glycerol shocks increase the calcium phosphate transfection of non-synchronized CHO cells. Biotechnology Letters. 28: 1827-33. PMID 17009090 DOI: 10.1007/s10529-006-9167-7  0.089
2009 Zhang X, Bürki CA, Stettler M, De Sanctis D, Perrone M, Discacciati M, Parolini N, DeJesus M, Hacker DL, Quarteroni A, Wurm FM. Efficient oxygen transfer by surface aeration in shaken cylindrical containers for mammalian cell cultivation at volumetric scales up to 1000 L Biochemical Engineering Journal. 45: 41-47. DOI: 10.1016/j.bej.2009.02.003  0.089
2012 Tissot S, Michel PO, Hacker DL, Baldi L, De Jesus M, Wurm FM. k(L)a as a predictor for successful probe-independent mammalian cell bioprocesses in orbitally shaken bioreactors. New Biotechnology. 29: 387-94. PMID 22142586 DOI: 10.1016/j.nbt.2011.10.010  0.088
2011 Tissot S, Monteil DT, Baldi L, Hacker DL, Wurm FM. kLa as a predictor for probe-independent mammalian cell bioprocesses in orbitally shaken bioreactors. Bmc Proceedings. 5: P36. PMID 22373050 DOI: 10.1186/1753-6561-5-S8-P36  0.088
2016 Zhu LK, Monteil DT, Shen X, Hacker DL, Song BY, Wang ZL, De Jesus M, Wurm FM. Studies on Fluid Dynamics of the Flow Field and Gas Transfer in Orbitally Shaken Tubes. Biotechnology Progress. PMID 27690196 DOI: 10.1002/btpr.2375  0.086
2013 Monteil DT, Tontodonati G, Ghimire S, Baldi L, Hacker DL, Bürki CA, Wurm FM. Disposable 600-mL orbitally shaken bioreactor for mammalian cell cultivation in suspension Biochemical Engineering Journal. 76: 6-12. DOI: 10.1016/j.bej.2013.04.008  0.083
2012 Angelini A, Diderich P, Morales-Sanfrutos J, Thurnheer S, Hacker D, Menin L, Heinis C. Chemical macrocyclization of peptides fused to antibody Fc fragments. Bioconjugate Chemistry. 23: 1856-63. PMID 22812498 DOI: 10.1021/bc300184m  0.079
2011 Kiseljak D, Rajendra Y, Manoli SS, Baldi L, Hacker DL, Wurm FM. The use of filler DNA for improved transfection and reduced DNA needs in transient gene expression with CHO and HEK cells. Bmc Proceedings. 5: P33. PMID 22373474 DOI: 10.1186/1753-6561-5-S8-P33  0.078
2008 Zhang X, Stettler M, Reif O, Kocourek A, Dejesus M, Hacker DL, Wurm FM. Shaken helical track bioreactors: Providing oxygen to high-density cultures of mammalian cells at volumes up to 1000 L by surface aeration with air. New Biotechnology. 25: 68-75. PMID 18504021 DOI: 10.1016/j.nbt.2008.03.001  0.074
2011 Matasci M, Bachmann V, Baldi L, Hacker DL, De Jesus M, Wurm FM. CHO cell lines generated by PiggyBac transposition. Bmc Proceedings. 5: P31. PMID 22373414 DOI: 10.1186/1753-6561-5-S8-P31  0.071
2010 Tissot S, Farhat M, Hacker DL, Anderlei T, Kühner M, Comninellis C, Wurm F. Determination of a scale-up factor from mixing time studies in orbitally shaken bioreactors Biochemical Engineering Journal. 52: 181-186. DOI: 10.1016/J.Bej.2010.08.005  0.071
2020 Zhu L, Xu B, Wu X, Lei J, Hacker DL, Liang X, Wurm FM. Analysis of volumetric mass transfer coefficient () in small- (250 mL) to large-scale (2500 L) orbitally shaken bioreactors. 3 Biotech. 10: 397. PMID 32850285 DOI: 10.1007/s13205-020-02352-9  0.069
2010 Werner S, Eibl R, Lettenbauer C, Röll M, Eibl D, De Jesus M, Zhang X, Stettler M, Tissot S, Bürki C, Broccard G, Kühner M, Tanner R, Baldi L, Hacker D, et al. Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers--a Swiss contribution. Chimia. 64: 819-23. PMID 21197848 DOI: 10.2533/chimia.2010.819  0.068
2013 Shen X, Hacker DL, Baldi L, Wurm FM. Study of the improved Sf9 transient gene expression process Bmc Proceedings. 7: P19. DOI: 10.1186/1753-6561-7-S6-P19  0.067
2011 Wurm FM, Hacker D. First CHO genome. Nature Biotechnology. 29: 718-20. PMID 21822249 DOI: 10.1038/nbt.1943  0.051
2023 Hacker D, Jones CA, Yasin E, Preece S, Davies H, Hawkins A, Belli A, Paton E. Cognitive outcome following complicated mild Traumatic Brain Injury: A literature review and meta-analysis. Journal of Neurotrauma. PMID 36964755 DOI: 10.1089/neu.2023.0020  0.048
2020 Forcione M, Chiarelli AM, Perpetuini D, Davies DJ, O'Halloran P, Hacker D, Merla A, Belli A. Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion: An Observational Case Study. International Journal of Molecular Sciences. 21. PMID 32872557 DOI: 10.3390/ijms21176273  0.046
2020 Zhu L, Xu B, Wu X, Lei J, Hacker DL, Liang X, Wurm FM. Analysis of volumetric mass transfer coefficient (kLa) in small- (250 mL) to large-scale (2500 L) orbitally shaken bioreactors 3 Biotech. 10. DOI: 10.1007/s13205-020-02352-9  0.042
2008 Hacker D, Birchwood M, Tudway J, Meaden A, Amphlett C. Acting on voices: Omnipotence, sources of threat, and safety-seeking behaviours. The British Journal of Clinical Psychology / the British Psychological Society. 47: 201-13. PMID 17958943 DOI: 10.1348/014466507X249093  0.04
2018 Jones C, Hacker D, Xia J, Meaden A, Irving CB, Zhao S, Chen J, Shi C. Cognitive behavioural therapy plus standard care versus standard care for people with schizophrenia. The Cochrane Database of Systematic Reviews. 12: CD007964. PMID 30572373 DOI: 10.1002/14651858.CD007964.pub2  0.032
2023 Hacker D, Jones CA, Chan YM, Yasin E, Clowes Z, Belli A, Cooper J, Bose D, Hawkins A, Davies H, Paton E. Examining the validity of the Delis-Kaplan Executive Function System (D-KEFS) in traumatic brain injury. Journal of Neuropsychology. PMID 37313961 DOI: 10.1111/jnp.12329  0.032
2006 Bertschinger M, Burki C, Backliwal G, Hacker DL, Jordan M, Wurm FM. Polyethylenimine-based quality control assay for plasmid DNA. Analytical Biochemistry. 356: 309-11. PMID 16884675 DOI: 10.1016/j.ab.2006.05.002  0.031
2017 Su Z, Davies D, Bhavsar A, Hammond D, Hacker D, Evans S, Grey M, Belli A. The effect of persistent post-concussive symptoms on cognitive performance after sport concussion British Journal of Sports Medicine. 51: A36.3-A37. DOI: 10.1136/bjsports-2016-097270.93  0.026
2022 Krynicki CR, Hacker D, Jones CA. An evaluation of the convergent validity of a face-to-face and virtual neuropsychological assessment counter balanced. Journal of Neuropsychology. PMID 36440708 DOI: 10.1111/jnp.12300  0.026
2017 Hacker D, Jones CA, Clowes Z, Belli A, Su Z, Sitaraman M, Davies D, Taylor R, Flahive E, Travis C, O'Neil N, Pettigrew Y. The Development and Psychometric Evaluation of a Supplementary Index Score of the Neuropsychological Assessment Battery Screening Module that is Sensitive to Traumatic Brain Injury. Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. 32: 215-227. PMID 28365746 DOI: 10.1093/arclin/acw087  0.025
2013 Monteil DT, Bürki CA, Baldi L, Hacker DL, de Jesus M, Wurm FM. The optimization of a rapid low-cost alternative of large-scale medium sterilization Bmc Proceedings. 7: P45. DOI: 10.1186/1753-6561-7-S6-P45  0.024
2012 Jones C, Hacker D, Cormac I, Meaden A, Irving CB. Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia. The Cochrane Database of Systematic Reviews. CD008712. PMID 22513966 DOI: 10.1002/14651858.CD008712.pub2  0.024
2018 Jones C, Hacker D, Meaden A, Cormac I, Irving CB, Xia J, Zhao S, Shi C, Chen J. Cognitive behavioural therapy plus standard care versus standard care plus other psychosocial treatments for people with schizophrenia. The Cochrane Database of Systematic Reviews. 11: CD008712. PMID 30480760 DOI: 10.1002/14651858.CD008712.pub3  0.023
2011 Jones C, Hacker D, Meaden A, Cormac I, Irving CB. WITHDRAWN: Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia. The Cochrane Database of Systematic Reviews. CD000524. PMID 21491377 DOI: 10.1002/14651858.CD000524.pub3  0.022
2012 Discacciati M, Hacker D, Quarteroni A, Quinodoz S, Tissot S, Wurm FM. Numerical simulation of orbitally shaken viscous fluids with free surface International Journal For Numerical Methods in Fluids. 71: 294-315. DOI: 10.1002/FLD.3658  0.018
2012 Jones C, Hacker D, Cormac I, Meaden A, Irving CB. Cognitive behavior therapy versus other psychosocial treatments for schizophrenia. Schizophrenia Bulletin. 38: 908-10. PMID 22987848 DOI: 10.1093/schbul/sbs090  0.016
2019 Jones C, Hacker D, Cormac I, Meaden A, Irving CB, Xia J, Zhao S, Shi C, Chen J. Cognitive Behavioral Therapy Plus Standard Care Versus Standard Care Plus Other Psychosocial Treatments for People With Schizophrenia. Schizophrenia Bulletin. 45: 284-286. PMID 30843049 DOI: 10.1093/schbul/sby188  0.016
2002 Gooden E, Witterick IJ, Hacker D, Rosen IB, Freeman JL. Parotid gland tumours in 255 consecutive patients: Mount Sinai Hospital's quality assurance review. The Journal of Otolaryngology. 31: 351-4. PMID 12593546 DOI: 10.2310/7070.2002.34394  0.014
2018 Zhu L, Monteil DT, Wang Y, Song B, Hacker DL, Wurm MJ, Li X, Wang Z, Wurm FM. Fluid dynamics of flow fields in a disposable 600-mL orbitally shaken bioreactor Biochemical Engineering Journal. 129: 84-95. DOI: 10.1016/J.BEJ.2017.10.019  0.01
2012 Meaden A, Hacker D, de Villiers A, Carbourne J, Paget A. Developing a measurement of engagement: the Residential Rehabilitation Engagement Scale for psychosis. Journal of Mental Health (Abingdon, England). 21: 182-91. PMID 22559829 DOI: 10.3109/09638237.2012.664301  0.01
2011 Tissot S, Reclari M, Quinodoz S, Dreyer M, Monteil DT, Baldi L, Hacker DL, Farhat M, Discacciati M, Quarteroni A, Wurm FM. Hydrodynamic stress in orbitally shaken bioreactors. Bmc Proceedings. 5: P39. PMID 22373127 DOI: 10.1186/1753-6561-5-S8-P39  0.01
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