Stanley M. Lemon - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Microbiology Biology, Molecular Biology

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zhou S, Williford SE, McGivern DR, Burch CL, Hu F, Benzine T, Ingravallo P, Asante-Appiah E, Howe AYM, Swanstrom R, Lemon SM. Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus. Antiviral Research. PMID 30081054 DOI: 10.1016/j.antiviral.2018.07.024  0.36
2017 Parr JB, Lodge EK, Holzmayer V, Pepin J, Frost EH, Fried MW, McGivern DR, Lemon SM, Keeler C, Emch M, Mwandagalirwa K, Tshefu A, Fwamba F, Muwonga J, Meshnick SR, et al. An Efficient, Large-Scale Survey of Hepatitis C Viremia in the Democratic Republic of the Congo Using Dried Blood Spots. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29048459 DOI: 10.1093/cid/cix771  0.36
2017 Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM. NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR. Nature Immunology. PMID 28967880 DOI: 10.1038/ni.3853  0.36
2017 Benzine T, Brandt R, Lovell WC, Yamane D, Neddermann P, De Francesco R, Lemon SM, Perelson AS, Ke R, McGivern DR. NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains. Plos Pathogens. 13: e1006343. PMID 28594932 DOI: 10.1371/journal.ppat.1006343  0.36
2017 Mitchell JK, Midkiff BR, Israelow B, Evans MJ, Lanford RE, Walker CM, Lemon SM, McGivern DR. Hepatitis C Virus Indirectly Disrupts DNA Damage-Induced p53 Responses by Activating Protein Kinase R. Mbio. 8. PMID 28442604 DOI: 10.1128/mBio.00121-17  0.36
2017 Yamane D, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM. Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3' variants. Nucleic Acids Research. PMID 28082397 DOI: 10.1093/nar/gkw1332  0.36
2016 Bility MT, Nio K, Li F, McGivern DR, Lemon SM, Feeney ER, Chung RT, Su L. Chronic hepatitis C infection-induced liver fibrogenesis is associated with M2 macrophage activation. Scientific Reports. 6: 39520. PMID 28000758 DOI: 10.1038/srep39520  0.36
2016 Hirai-Yuki A, Hensley L, McGivern DR, González-López O, Das A, Feng H, Sun L, Wilson JE, Hu F, Feng Z, Lovell W, Misumi I, Ting JP, Montgomery S, Cullen J, ... ... Lemon SM, et al. MAVS-dependent host species range and pathogenicity of human hepatitis A virus. Science (New York, N.Y.). PMID 27633528 DOI: 10.1126/science.aaf8325  0.6
2015 Selitsky SR, Dinh TA, Toth CL, Kurtz CL, Honda M, Struck BR, Kaneko S, Vickers KC, Lemon SM, Sethupathy P. Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. Mbio. 6. PMID 26646011 DOI: 10.1128/mBio.01500-15  0.6
2015 Mitchell JK, Lemon SM, McGivern DR. How do persistent infections with hepatitis C virus cause liver cancer? Current Opinion in Virology. 14: 101-8. PMID 26426687 DOI: 10.1016/j.coviro.2015.09.003  0.6
2015 Zhou K, Hu F, Wang C, Xu M, Lan Y, Morano JP, Lemon SM, Tucker JD, Cai W. Genotypic distribution and hepatic fibrosis among HIV/HCV co-infected individuals in Southern China: a retrospective cross-sectional study. Bmc Infectious Diseases. 15: 401. PMID 26424404 DOI: 10.1186/s12879-015-1135-1  0.6
2015 Wang Y, McGivern DR, Cheng L, Li G, Lemon SM, Niu J, Su L, Reszka-Blanco NJ. Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. Plos One. 10: e0135232. PMID 26274905 DOI: 10.1371/journal.pone.0135232  0.6
2015 Li Y, Yamane D, Masaki T, Lemon SM. The yin and yang of hepatitis C: synthesis and decay of hepatitis C virus RNA. Nature Reviews. Microbiology. 13: 544-58. PMID 26256788 DOI: 10.1038/nrmicro3506  0.6
2015 Mauger DM, Golden M, Yamane D, Williford S, Lemon SM, Martin DP, Weeks KM. Functionally conserved architecture of hepatitis C virus RNA genomes. Proceedings of the National Academy of Sciences of the United States of America. 112: 3692-7. PMID 25775547 DOI: 10.1073/pnas.1416266112  0.6
2015 Li Y, Yamane D, Lemon SM. Dissecting the roles of the 5' exoribonucleases Xrn1 and Xrn2 in restricting hepatitis C virus replication. Journal of Virology. 89: 4857-65. PMID 25673723 DOI: 10.1128/JVI.03692-14  0.6
2015 Masaki T, Arend KC, Li Y, Yamane D, McGivern DR, Kato T, Wakita T, Moorman NJ, Lemon SM. miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation. Cell Host & Microbe. 17: 217-28. PMID 25662750 DOI: 10.1016/j.chom.2014.12.014  0.6
2015 Walker CM, Feng Z, Lemon SM. Reassessing immune control of hepatitis A virus. Current Opinion in Virology. 11: 7-13. PMID 25617494 DOI: 10.1016/j.coviro.2015.01.003  0.6
2015 Selitsky SR, Baran-Gale J, Honda M, Yamane D, Masaki T, Fannin EE, Guerra B, Shirasaki T, Shimakami T, Kaneko S, Lanford RE, Lemon SM, Sethupathy P. Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C. Scientific Reports. 5: 7675. PMID 25567797 DOI: 10.1038/srep07675  0.6
2015 Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M, et al. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology. 148: 392-402.e13. PMID 25447848 DOI: 10.1053/j.gastro.2014.10.040  0.6
2015 Feng Z, Li Y, McKnight KL, Hensley L, Lanford RE, Walker CM, Lemon SM. Human pDCs preferentially sense enveloped hepatitis A virions. The Journal of Clinical Investigation. 125: 169-76. PMID 25415438 DOI: 10.1172/JCI77527  0.6
2014 Jabara CB, Hu F, Mollan KR, Williford SE, Menezes P, Yang Y, Eron JJ, Fried MW, Hudgens MG, Jones CD, Swanstrom R, Lemon SM. Hepatitis C Virus (HCV) NS3 sequence diversity and antiviral resistance-associated variant frequency in HCV/HIV coinfection. Antimicrobial Agents and Chemotherapy. 58: 6079-92. PMID 25092699 DOI: 10.1128/AAC.03466-14  0.6
2014 Yamane D, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, ... ... Lemon SM, et al. Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation. Nature Medicine. 20: 927-35. PMID 25064127 DOI: 10.1038/nm.3610  0.6
2014 Shirasaki T, Honda M, Shimakami T, Murai K, Shiomoto T, Okada H, Takabatake R, Tokumaru A, Sakai Y, Yamashita T, Lemon SM, Murakami S, Kaneko S. Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway. Hepatology (Baltimore, Md.). 60: 1519-30. PMID 24962339 DOI: 10.1002/hep.27277  0.6
2014 McGivern DR, Masaki T, Williford S, Ingravallo P, Feng Z, Lahser F, Asante-Appiah E, Neddermann P, De Francesco R, Howe AY, Lemon SM. Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitors. Gastroenterology. 147: 453-62.e7. PMID 24768676 DOI: 10.1053/j.gastro.2014.04.021  0.6
2014 Masaki T, Matsunaga S, Takahashi H, Nakashima K, Kimura Y, Ito M, Matsuda M, Murayama A, Kato T, Hirano H, Endo Y, Lemon SM, Wakita T, Sawasaki T, Suzuki T. Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production. Journal of Virology. 88: 7541-55. PMID 24760886 DOI: 10.1128/JVI.03170-13  0.6
2014 Shimakami T, Honda M, Shirasaki T, Takabatake R, Liu F, Murai K, Shiomoto T, Funaki M, Yamane D, Murakami S, Lemon SM, Kaneko S. The acyclic retinoid Peretinoin inhibits hepatitis C virus replication and infectious virus release in vitro. Scientific Reports. 4: 4688. PMID 24732793 DOI: 10.1038/srep04688  0.6
2014 Li Y, Masaki T, Shimakami T, Lemon SM. hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication. Journal of Virology. 88: 7199-209. PMID 24719423 DOI: 10.1128/JVI.00225-14  0.6
2014 Yi M, Hu F, Joyce M, Saxena V, Welsch C, Chavez D, Guerra B, Yamane D, Veselenak R, Pyles R, Walker CM, Tyrrell L, Bourne N, Lanford RE, Lemon SM. Evolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzee. Journal of Virology. 88: 3678-94. PMID 24429362 DOI: 10.1128/JVI.03540-13  0.6
2014 Feng Z, Lemon SM. Peek-a-boo: membrane hijacking and the pathogenesis of viral hepatitis. Trends in Microbiology. 22: 59-64. PMID 24268716 DOI: 10.1016/j.tim.2013.10.005  0.6
2014 Rusyn I, Lemon SM. Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies? Cancer Letters. 345: 210-5. PMID 23871966 DOI: 10.1016/j.canlet.2013.06.028  0.6
2013 Honegger JR, Kim S, Price AA, Kohout JA, McKnight KL, Prasad MR, Lemon SM, Grakoui A, Walker CM. Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses. Nature Medicine. 19: 1529-33. PMID 24162814 DOI: 10.1038/nm.3351  0.6
2013 Spaniel C, Honda M, Selitsky SR, Yamane D, Shimakami T, Kaneko S, Lanford RE, Lemon SM. microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection. Plos One. 8: e76867. PMID 24130799 DOI: 10.1371/journal.pone.0076867  0.6
2013 Li Y, Masaki T, Lemon SM. miR-122 and the Hepatitis C RNA genome: more than just stability. Rna Biology. 10: 919-23. PMID 23770926 DOI: 10.4161/rna.25137  0.6
2013 Dansako H, Yamane D, Welsch C, McGivern DR, Hu F, Kato N, Lemon SM. Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells. Plos Pathogens. 9: e1003345. PMID 23717201 DOI: 10.1371/journal.ppat.1003345  0.6
2013 Feng Z, Hensley L, McKnight KL, Hu F, Madden V, Ping L, Jeong SH, Walker C, Lanford RE, Lemon SM. A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature. 496: 367-71. PMID 23542590 DOI: 10.1038/nature12029  0.6
2013 Yamane D, McGivern DR, Masaki T, Lemon SM. Liver injury and disease pathogenesis in chronic hepatitis C. Current Topics in Microbiology and Immunology. 369: 263-88. PMID 23463205 DOI: 10.1007/978-3-642-27340-7_11  0.6
2013 Shirasaki T, Honda M, Shimakami T, Horii R, Yamashita T, Sakai Y, Sakai A, Okada H, Watanabe R, Murakami S, Yi M, Lemon SM, Kaneko S. MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells. Journal of Virology. 87: 5270-86. PMID 23449803 DOI: 10.1128/JVI.03022-12  0.6
2013 Kim S, Ishida H, Yamane D, Yi M, Swinney DC, Foung S, Lemon SM. Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry. Journal of Virology. 87: 4214-24. PMID 23365451 DOI: 10.1128/JVI.00954-12  0.6
2013 Li Y, Masaki T, Yamane D, McGivern DR, Lemon SM. Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication. Proceedings of the National Academy of Sciences of the United States of America. 110: 1881-6. PMID 23248316 DOI: 10.1073/pnas.1213515110  0.6
2013 Lau DT, Negash A, Chen J, Crochet N, Sinha M, Zhang Y, Guedj J, Holder S, Saito T, Lemon SM, Luxon BA, Perelson AS, Gale M. Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection. Gastroenterology. 144: 402-413.e12. PMID 23123437 DOI: 10.1053/j.gastro.2012.10.044  0.6
2013 Li K, Lemon SM. Innate immune responses in hepatitis C virus infection. Seminars in Immunopathology. 35: 53-72. PMID 22868377 DOI: 10.1007/s00281-012-0332-x  0.6
2012 Bataller R, Lemon SM. Fueling fibrosis in chronic hepatitis C. Proceedings of the National Academy of Sciences of the United States of America. 109: 14293-4. PMID 22927398 DOI: 10.1073/pnas.1212048109  0.6
2012 Zhou Y, Callendret B, Xu D, Brasky KM, Feng Z, Hensley LL, Guedj J, Perelson AS, Lemon SM, Lanford RE, Walker CM. Dominance of the CD4(+) T helper cell response during acute resolving hepatitis A virus infection. The Journal of Experimental Medicine. 209: 1481-92. PMID 22753925 DOI: 10.1084/jem.20111906  0.6
2012 Gray RR, Strickland SL, Veras NM, Goodenow MM, Pybus OG, Lemon SM, Fried MW, Nelson DR, Salemi M. Unexpected maintenance of hepatitis C viral diversity following liver transplantation. Journal of Virology. 86: 8432-9. PMID 22623804 DOI: 10.1128/JVI.00749-12  0.6
2012 Lemon SM, McGivern DR. Is hepatitis C virus carcinogenic? Gastroenterology. 142: 1274-8. PMID 22537433 DOI: 10.1053/j.gastro.2012.01.045  0.6
2012 Shimakami T, Yamane D, Welsch C, Hensley L, Jangra RK, Lemon SM. Base pairing between hepatitis C virus RNA and microRNA 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus. Journal of Virology. 86: 7372-83. PMID 22532678 DOI: 10.1128/JVI.00513-12  0.6
2012 Keck ZY, Xia J, Wang Y, Wang W, Krey T, Prentoe J, Carlsen T, Li AY, Patel AH, Lemon SM, Bukh J, Rey FA, Foung SK. Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate. Plos Pathogens. 8: e1002653. PMID 22511875 DOI: 10.1371/journal.ppat.1002653  0.6
2012 Berns KI, Casadevall A, Cohen ML, Ehrlich SA, Enquist LW, Fitch JP, Franz DR, Fraser-Liggett CM, Grant CM, Imperiale MJ, Kanabrocki J, Keim PS, Lemon SM, Levy SB, Lumpkin JR, et al. Public health and biosecurity. Adaptations of avian flu virus are a cause for concern. Science (New York, N.Y.). 335: 660-1. PMID 22294736 DOI: 10.1126/science.1217994  0.6
2012 Berns KI, Casadevall A, Cohen ML, Ehrlich SA, Enquist LW, Fitch JP, Franz DR, Fraser-Liggett CM, Grant CM, Imperiale MJ, Kanabrocki J, Keim PS, Lemon SM, Levy SB, Lumpkin JR, et al. Policy: Adaptations of avian flu virus are a cause for concern. Nature. 482: 153-4. PMID 22294204 DOI: 10.1038/482153a  0.6
2012 Welsch C, Schweizer S, Shimakami T, Domingues FS, Kim S, Lemon SM, Antes I. Ketoamide resistance and hepatitis C virus fitness in val55 variants of the NS3 serine protease. Antimicrobial Agents and Chemotherapy. 56: 1907-15. PMID 22252823 DOI: 10.1128/AAC.05184-11  0.6
2012 Shimakami T, Yamane D, Jangra RK, Kempf BJ, Spaniel C, Barton DJ, Lemon SM. Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proceedings of the National Academy of Sciences of the United States of America. 109: 941-6. PMID 22215596 DOI: 10.1073/pnas.1112263109  0.6
2012 Welsch C, Shimakami T, Hartmann C, Yang Y, Domingues FS, Lengauer T, Zeuzem S, Lemon SM. Peptidomimetic escape mechanisms arise via genetic diversity in the ligand-binding site of the hepatitis C virus NS3/4A serine protease. Gastroenterology. 142: 654-63. PMID 22155364 DOI: 10.1053/j.gastro.2011.11.035  0.6
2011 Helbig KJ, Eyre NS, Yip E, Narayana S, Li K, Fiches G, McCartney EM, Jangra RK, Lemon SM, Beard MR. The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A. Hepatology (Baltimore, Md.). 54: 1506-17. PMID 22045669 DOI: 10.1002/hep.24542  0.6
2011 Qu L, Feng Z, Yamane D, Liang Y, Lanford RE, Li K, Lemon SM. Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD. Plos Pathogens. 7: e1002169. PMID 21931545 DOI: 10.1371/journal.ppat.1002169  0.6
2011 McGivern DR, Lemon SM. Model systems for hepatitis C research: the cup half empty? Gastroenterology. 141: 806-9. PMID 21791207 DOI: 10.1053/j.gastro.2011.07.028  0.6
2011 Lanford RE, Feng Z, Chavez D, Guerra B, Brasky KM, Zhou Y, Yamane D, Perelson AS, Walker CM, Lemon SM. Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA. Proceedings of the National Academy of Sciences of the United States of America. 108: 11223-8. PMID 21690403 DOI: 10.1073/pnas.1101939108  0.6
2011 Luo Y, Lou S, Deng X, Liu Z, Li Y, Kleiboeker S, Qiu J. Parvovirus B19 infection of human primary erythroid progenitor cells triggers ATR-Chk1 signaling, which promotes B19 virus replication. Journal of Virology. 85: 8046-55. PMID 21680529 DOI: 10.1128/JVI.00831-11  0.6
2011 Kannan RP, Hensley LL, Evers LE, Lemon SM, McGivern DR. Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis. Journal of Virology. 85: 7989-8001. PMID 21680513 DOI: 10.1128/JVI.00280-11  0.36
2011 Sabo MC, Luca VC, Prentoe J, Hopcraft SE, Blight KJ, Yi M, Lemon SM, Ball JK, Bukh J, Evans MJ, Fremont DH, Diamond MS. Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step. Journal of Virology. 85: 7005-19. PMID 21543495 DOI: 10.1128/JVI.00586-11  0.6
2011 Kim S, Welsch C, Yi M, Lemon SM. Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III. Journal of Virology. 85: 6645-56. PMID 21525356 DOI: 10.1128/JVI.02156-10  0.6
2011 Honda M, Takehana K, Sakai A, Tagata Y, Shirasaki T, Nishitani S, Muramatsu T, Yamashita T, Nakamoto Y, Mizukoshi E, Sakai Y, Yamashita T, Nakamura M, Shimakami T, Yi M, ... Lemon SM, et al. Malnutrition impairs interferon signaling through mTOR and FoxO pathways in patients with chronic hepatitis C. Gastroenterology. 141: 128-40, 140.e1-2. PMID 21458454 DOI: 10.1053/j.gastro.2011.03.051  0.6
2011 McGivern DR, Lemon SM. Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer Oncogene. 30: 1969-1983. PMID 21258404 DOI: 10.1038/onc.2010.594  0.6
2011 Shimakami T, Welsch C, Yamane D, McGivern DR, Yi M, Zeuzem S, Lemon SM. Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus. Gastroenterology. 140: 667-75. PMID 21056040 DOI: 10.1053/j.gastro.2010.10.056  0.6
2011 Zhou Z, Wang N, Woodson SE, Dong Q, Wang J, Liang Y, Rijnbrand R, Wei L, Nichols JE, Guo JT, Holbrook MR, Lemon SM, Li K. Antiviral activities of ISG20 in positive-strand RNA virus infections. Virology. 409: 175-88. PMID 21036379 DOI: 10.1016/j.virol.2010.10.008  0.6
2011 Ma Y, Anantpadma M, Timpe JM, Shanmugam S, Singh SM, Lemon SM, Yi M. Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins. Journal of Virology. 85: 86-97. PMID 20962101 DOI: 10.1128/JVI.01070-10  0.6
2011 Darling JM, Lemon SM, Fried MW. Hepatitis C Schiff's Diseases of the Liver. 582-652. DOI: 10.1002/9781119950509.ch25  0.6
2010 Qu L, Lemon SM. Hepatitis A and hepatitis C viruses: divergent infection outcomes marked by similarities in induction and evasion of interferon responses. Seminars in Liver Disease. 30: 319-32. PMID 20960373 DOI: 10.1055/s-0030-1267534  0.6
2010 Wozniak AL, Griffin S, Rowlands D, Harris M, Yi M, Lemon SM, Weinman SA. Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production. Plos Pathogens. 6: e1001087. PMID 20824094 DOI: 10.1371/journal.ppat.1001087  0.6
2010 Gal-Tanamy M, Zemel R, Bachmatov L, Jangra RK, Shapira A, Villanueva RA, Yi M, Lemon SM, Benhar I, Tur-Kaspa R. Inhibition of protease-inhibitor-resistant hepatitis C virus replicons and infectious virus by intracellular intrabodies. Antiviral Research. 88: 95-106. PMID 20705106 DOI: 10.1016/j.antiviral.2010.08.001  0.6
2010 Villanueva RA, Jangra RK, Yi M, Pyles R, Bourne N, Lemon SM. miR-122 does not modulate the elongation phase of hepatitis C virus RNA synthesis in isolated replicase complexes. Antiviral Research. 88: 119-23. PMID 20637242 DOI: 10.1016/j.antiviral.2010.07.004  0.6
2010 Stavrou S, Feng Z, Lemon SM, Roos RP. Different strains of Theiler's murine encephalomyelitis virus antagonize different sites in the type I interferon pathway. Journal of Virology. 84: 9181-9. PMID 20610716 DOI: 10.1128/JVI.00603-10  0.6
2010 Lemon SM. Induction and evasion of innate antiviral responses by hepatitis C virus. The Journal of Biological Chemistry. 285: 22741-7. PMID 20457596 DOI: 10.1074/jbc.R109.099556  0.6
2010 Jangra RK, Yi M, Lemon SM. Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122. Journal of Virology. 84: 6615-25. PMID 20427538 DOI: 10.1128/JVI.00417-10  0.6
2010 Lemon SM, McKeating JA, Pietschmann T, Frick DN, Glenn JS, Tellinghuisen TL, Symons J, Furman PA. Development of novel therapies for hepatitis C. Antiviral Research. 86: 79-92. PMID 20417376 DOI: 10.1016/j.antiviral.2010.02.003  0.6
2010 Jangra RK, Yi M, Lemon SM. DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation. Journal of Virology. 84: 6810-24. PMID 20392846 DOI: 10.1128/JVI.00397-10  0.6
2010 Shetty S, Kim S, Shimakami T, Lemon SM, Mihailescu MR. Hepatitis C virus genomic RNA dimerization is mediated via a kissing complex intermediate. Rna (New York, N.Y.). 16: 913-25. PMID 20360391 DOI: 10.1261/rna.1960410  0.6
2010 Pierucci-Lagha A, Covault J, Bonkovsky HL, Feinn R, Abreu C, Sterling RK, Fontana RJ, Kranzler HR, Szabo G, Cormier M, Giansiracusa D, Kelley M, DiBisceglie AM, Bacon B, Neuschwander-Tetri B, ... ... Lemon SM, et al. A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-α treatment Psychosomatics. 51: 137-148. PMID 20332289 DOI: 10.1176/appi.psy.51.2.137  0.6
2010 Wang N, Dong Q, Li J, Jangra RK, Fan M, Brasier AR, Lemon SM, Pfeffer LM, Li K. Viral induction of the zinc finger antiviral protein is IRF3-dependent but NF-kappaB-independent. The Journal of Biological Chemistry. 285: 6080-90. PMID 20048147 DOI: 10.1074/jbc.M109.054486  0.6
2010 Wang T, Campbell RV, Yi MK, Lemon SM, Weinman SA. Role of Hepatitis C virus core protein in viral-induced mitochondrial dysfunction. Journal of Viral Hepatitis. 17: 784-93. PMID 20002299 DOI: 10.1111/j.1365-2893.2009.01238.x  0.6
2010 Fox JG, Feng Y, Theve EJ, Raczynski AR, Fiala JL, Doernte AL, Williams M, McFaline JL, Essigmann JM, Schauer DB, Tannenbaum SR, Dedon PC, Weinman SA, Lemon SM, Fry RC, et al. Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens. Gut. 59: 88-97. PMID 19850960 DOI: 10.1136/gut.2009.183749  0.6
2010 Angus AG, Dalrymple D, Boulant S, McGivern DR, Clayton RF, Scott MJ, Adair R, Graham S, Owsianka AM, Targett-Adams P, Li K, Wakita T, McLauchlan J, Lemon SM, Patel AH. Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein. The Journal of General Virology. 91: 122-32. PMID 19793905 DOI: 10.1099/vir.0.015909-0  0.6
2009 Shimakami T, Lanford RE, Lemon SM. Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities. Current Opinion in Pharmacology. 9: 537-44. PMID 19762279 DOI: 10.1016/j.coph.2009.08.008  0.6
2009 Liang Y, Shilagard T, Xiao SY, Snyder N, Lau D, Cicalese L, Weiss H, Vargas G, Lemon SM. Visualizing hepatitis C virus infections in human liver by two-photon microscopy. Gastroenterology. 137: 1448-58. PMID 19632233 DOI: 10.1053/j.gastro.2009.07.050  0.6
2009 Wang N, Liang Y, Devaraj S, Wang J, Lemon SM, Li K. Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. Journal of Virology. 83: 9824-34. PMID 19625408 DOI: 10.1128/JVI.01125-09  0.6
2009 Weatherford T, Chavez D, Brasky KM, Lemon SM, Martin A, Lanford RE. Lack of adaptation of chimeric GB virus B/hepatitis C virus in the marmoset model: possible effects of bottleneck. Journal of Virology. 83: 8062-75. PMID 19474092 DOI: 10.1128/JVI.00032-09  0.6
2009 McGivern DR, Villanueva RA, Chinnaswamy S, Kao CC, Lemon SM. Impaired replication of hepatitis C virus containing mutations in a conserved NS5B retinoblastoma protein-binding motif. Journal of Virology. 83: 7422-33. PMID 19458004 DOI: 10.1128/JVI.00262-09  0.6
2009 Yi M, Ma Y, Yates J, Lemon SM. Trans-complementation of an NS2 defect in a late step in hepatitis C virus (HCV) particle assembly and maturation. Plos Pathogens. 5: e1000403. PMID 19412343 DOI: 10.1371/journal.ppat.1000403  0.6
2009 Warter L, Cohen L, Benureau Y, Chavez D, Yang Y, Bodola F, Lemon SM, Traboni C, Lanford RE, Martin A. A cooperative interaction between nontranslated RNA sequences and NS5A protein promotes in vivo fitness of a chimeric hepatitis C/GB virus B. Plos One. 4: e4419. PMID 19204793 DOI: 10.1371/journal.pone.0004419  0.6
2009 Lanford RE, Evans MJ, Lohmann V, Lindenbach B, Gale M, Rehermann B, Chang KM, Lemon SM. The accelerating pace of HCV research: a summary of the 15th International Symposium on Hepatitis C Virus And Related Viruses. Gastroenterology. 136: 9-16. PMID 19026648 DOI: 10.1053/j.gastro.2008.11.019  0.6
2009 Yi M, Lemon SM. Genotype 1a HCV (H77S) infection system. Methods in Molecular Biology (Clifton, N.J.). 510: 337-46. PMID 19009273 DOI: 10.1007/978-1-59745-394-3_25  0.6
2009 McGivern DR, Lemon SM. Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer. Annual Review of Pathology. 4: 399-415. PMID 18928409 DOI: 10.1146/annurev.pathol.4.110807.092202  0.6
2009 Lemon SM, Farci P, Ghany MG. Viral Escape Mechanisms in Hepatitis C and the Clinical Consequences of Persistent Infection The Liver: Biology and Pathobiology: Fifth Edition. 877-897. DOI: 10.1002/9780470747919.ch53  0.6
2008 Gal-Tanamy M, Keck ZY, Yi M, McKeating JA, Patel AH, Foung SK, Lemon SM. In vitro selection of a neutralization-resistant hepatitis C virus escape mutant. Proceedings of the National Academy of Sciences of the United States of America. 105: 19450-5. PMID 19052239 DOI: 10.1073/pnas.0809879105  0.6
2008 Liang Y, Ishida H, Lenz O, Lin TI, Nyanguile O, Simmen K, Pyles RB, Bourne N, Yi M, Li K, Lemon SM. Antiviral suppression vs restoration of RIG-I signaling by hepatitis C protease and polymerase inhibitors. Gastroenterology. 135: 1710-1718.e2. PMID 18725224 DOI: 10.1053/j.gastro.2008.07.023  0.6
2008 Yang Y, Yi M, Evans DJ, Simmonds P, Lemon SM. Identification of a conserved RNA replication element (cre) within the 3Dpol-coding sequence of hepatoviruses. Journal of Virology. 82: 10118-28. PMID 18684812 DOI: 10.1128/JVI.00787-08  0.6
2008 Ma Y, Yates J, Liang Y, Lemon SM, Yi M. NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly. Journal of Virology. 82: 7624-39. PMID 18508894 DOI: 10.1128/JVI.00724-08  0.6
2008 Chinnaswamy S, Yarbrough I, Palaninathan S, Kumar CT, Vijayaraghavan V, Demeler B, Lemon SM, Sacchettini JC, Kao CC. A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase. The Journal of Biological Chemistry. 283: 20535-46. PMID 18442978 DOI: 10.1074/jbc.M801490200  0.6
2008 Keck ZY, Li TK, Xia J, Gal-Tanamy M, Olson O, Li SH, Patel AH, Ball JK, Lemon SM, Foung SK. Definition of a conserved immunodominant domain on hepatitis C virus E2 glycoprotein by neutralizing human monoclonal antibodies. Journal of Virology. 82: 6061-6. PMID 18400849 DOI: 10.1128/JVI.02475-07  0.6
2008 Keck ZY, Olson O, Gal-Tanamy M, Xia J, Patel AH, Dreux M, Cosset FL, Lemon SM, Foung SK. A point mutation leading to hepatitis C virus escape from neutralization by a monoclonal antibody to a conserved conformational epitope. Journal of Virology. 82: 6067-72. PMID 18385242 DOI: 10.1128/JVI.00252-08  0.6
2008 Lau DT, Fish PM, Sinha M, Owen DM, Lemon SM, Gale M. Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. Hepatology (Baltimore, Md.). 47: 799-809. PMID 18203148 DOI: 10.1002/hep.22076  0.6
2008 Chung RT, Gale M, Polyak SJ, Lemon SM, Liang TJ, Hoofnagle JH. Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop. Hepatology (Baltimore, Md.). 47: 306-20. PMID 18161743 DOI: 10.1002/hep.22070  0.6
2007 Munakata T, Liang Y, Kim S, McGivern DR, Huibregtse J, Nomoto A, Lemon SM. Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein. Plos Pathogens. 3: 1335-47. PMID 17907805 DOI: 10.1371/journal.ppat.0030139  0.6
2007 Shen M, Wang Q, Yang Y, Pathak HB, Arnold JJ, Castro C, Lemon SM, Cameron CE. Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complex. Journal of Virology. 81: 12485-95. PMID 17855535 DOI: 10.1128/JVI.00972-07  0.6
2007 Saderholm MJ, Lemon SM, Erickson BW. Characterization of deltoid, a chimeric protein containing the oligomerization site of hepatitis delta antigen. Biopolymers. 88: 764-73. PMID 17542009 DOI: 10.1002/bip.20786  0.6
2007 Sampath R, Russell KL, Massire C, Eshoo MW, Harpin V, Blyn LB, Melton R, Ivy C, Pennella T, Li F, Levene H, Hall TA, Libby B, Fan N, Walcott DJ, ... ... Lemon SM, et al. Global surveillance of emerging Influenza virus genotypes by mass spectrometry. Plos One. 2: e489. PMID 17534439 DOI: 10.1371/journal.pone.0000489  0.6
2007 Chen Z, Rijnbrand R, Jangra RK, Devaraj SG, Qu L, Ma Y, Lemon SM, Li K. Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus. Virology. 366: 277-92. PMID 17531282 DOI: 10.1016/j.virol.2007.04.023  0.6
2007 Yang Y, Liang Y, Qu L, Chen Z, Yi M, Li K, Lemon SM. Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proceedings of the National Academy of Sciences of the United States of America. 104: 7253-8. PMID 17438296 DOI: 10.1073/pnas.0611506104  0.6
2007 Ishida H, Li K, Yi M, Lemon SM. p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells. The Journal of Biological Chemistry. 282: 11836-48. PMID 17255101 DOI: 10.1074/jbc.M610106200  0.6
2007 Chen Z, Benureau Y, Rijnbrand R, Yi J, Wang T, Warter L, Lanford RE, Weinman SA, Lemon SM, Martin A, Li K. GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS. Journal of Virology. 81: 964-76. PMID 17093192 DOI: 10.1128/JVI.02076-06  0.6
2007 Yi M, Ma Y, Yates J, Lemon SM. Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chirneric hepatitis C virus Journal of Virology. 81: 629-638. PMID 17079282 DOI: 10.1128/JVI.01890-06  0.6
2007 Tripathi RL, Krishnan P, He Y, Middleton T, Pilot-Matias T, Chen CM, Lau DT, Lemon SM, Mo H, Kati W, Molla A. Replication efficiency of chimeric replicon containing NS5A-5B genes derived from HCV-infected patient sera. Antiviral Research. 73: 40-9. PMID 16914212 DOI: 10.1016/j.antiviral.2006.07.005  0.6
2007 Lemon SM, Martin A. Structure and Molecular Virology Viral Hepatitis. 77-91. DOI: 10.1002/9780470987131.ch6  0.6
2006 Targett-Adams P, Schaller T, Hope G, Lanford RE, Lemon SM, Martin A, McLauchlan J. Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo. The Journal of Biological Chemistry. 281: 29221-7. PMID 16882659 DOI: 10.1074/jbc.M605373200  0.6
2006 Furutani T, Hino K, Okuda M, Gondo T, Nishina S, Kitase A, Korenaga M, Xiao SY, Weinman SA, Lemon SM, Sakaida I, Okita K. Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatitis C virus polyprotein. Gastroenterology. 130: 2087-98. PMID 16762631 DOI: 10.1053/j.gastro.2006.02.060  0.6
2006 Hara Y, Hino K, Okuda M, Furutani T, Hidaka I, Yamaguchi Y, Korenaga M, Li K, Weinman SA, Lemon SM, Okita K. Hepatitis C virus core protein inhibits deoxycholic acid-mediated apoptosis despite generating mitochondrial reactive oxygen species. Journal of Gastroenterology. 41: 257-68. PMID 16699860 DOI: 10.1007/s00535-005-1738-1  0.6
2006 Loo YM, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, Carney DS, Wang T, Ishida H, Yoneyama M, Fujita T, Saito T, Lee WM, Hagedorn CH, Lau DT, ... ... Lemon SM, et al. Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proceedings of the National Academy of Sciences of the United States of America. 103: 6001-6. PMID 16585524 DOI: 10.1073/pnas.0601523103  0.6
2006 Relman DA, Choffnes E, Lemon SM. In search of biosecurity. Science (New York, N.Y.). 311: 1835. PMID 16574824 DOI: 10.1126/science.1127725  0.6
2006 Yi M, Villanueva RA, Thomas DL, Wakita T, Lemon SM. Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells Proceedings of the National Academy of Sciences of the United States of America. 103: 2310-2315. PMID 16461899 DOI: 10.1073/pnas.0510727103  0.6
2006 Martin A, Lemon SM. Hepatitis A virus: From discovery to vaccines Hepatology. 43. PMID 16447259 DOI: 10.1002/hep.21052  0.6
2006 Keasler VV, Lerat H, Madden CR, Finegold MJ, McGarvey MJ, Mohammed EM, Forbes SJ, Lemon SM, Hadsell DL, Grona SJ, Hollinger FB, Slagle BL. Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein. Virology. 347: 466-75. PMID 16427673 DOI: 10.1016/j.virol.2005.11.050  0.6
2006 Yi M, Tong X, Skelton A, Chase R, Chen T, Prongay A, Bogen SL, Saksena AK, Njoroge FG, Veselenak RL, Pyles RB, Bourne N, Malcolm BA, Lemon SM. Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations. The Journal of Biological Chemistry. 281: 8205-15. PMID 16352601 DOI: 10.1074/jbc.M510246200  0.6
2006 Tagle M, Lemon SM, Schiff ER. Viral Hepatitis Tropical Infectious Diseases. 1: 694-725. DOI: 10.1016/B978-0-443-06668-9.50069-7  0.6
2006 Choffnes ER, Lemon SM, Relman DA. A brave new world in the life sciences Bulletin of the Atomic Scientists. 62.  0.6
2005 Munakata T, Nakamura M, Liang Y, Li K, Lemon SM. Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase Proceedings of the National Academy of Sciences of the United States of America. 102: 18159-18164. PMID 16332962 DOI: 10.1073/pnas.0505605102  0.6
2005 Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (New York, N.Y.). 309: 1577-81. PMID 16141076 DOI: 10.1126/science.1113329  0.6
2005 Sun J, Tumurbaatar B, Jia J, Diao H, Bodola F, Lemon SM, Tang W, Bowen DG, McCaughan GW, Bertolino P, Chan TS. Parenchymal expression of CD86/B7.2 contributes to hepatitis C virus-related liver injury. Journal of Virology. 79: 10730-9. PMID 16051865 DOI: 10.1128/JVI.79.16.10730-10739.2005  0.6
2005 Lau DT, Luxon BA, Xiao SY, Beard MR, Lemon SM. Intrahepatic gene expression profiles and alpha-smooth muscle actin patterns in hepatitis C virus induced fibrosis. Hepatology (Baltimore, Md.). 42: 273-81. PMID 15986378 DOI: 10.1002/hep.20767  0.6
2005 Bourne N, Pyles RB, Yi M, Veselenak RL, Davis MM, Lemon SM. Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system. Antiviral Research. 67: 76-82. PMID 15927278 DOI: 10.1016/j.antiviral.2005.03.006  0.6
2005 Lemon SM, Mahmoud AAF. The threat of pandemic influenza: Are we ready? Biosecurity and Bioterrorism. 3: 70-73. PMID 15853457 DOI: 10.1089/bsp.2005.3.70  0.6
2005 Rijnbrand R, Yang Y, Beales L, Bodola F, Goettge K, Cohen L, Lanford RE, Lemon SM, Martin A. A chimeric GB virus B with 5' nontranslated RNA sequence from hepatitis C virus causes hepatitis in tamarins. Hepatology (Baltimore, Md.). 41: 986-94. PMID 15793797 DOI: 10.1002/hep.20656  0.6
2005 Ferreon JC, Ferreon ACM, Li K, Lemon SM. Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease Journal of Biological Chemistry. 280: 20483-20492. PMID 15767257 DOI: 10.1074/jbc.M500422200  0.6
2005 Li K, Chen Z, Kato N, Gale M, Lemon SM. Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-β production in hepatocytes Journal of Biological Chemistry. 280: 16739-16747. PMID 15737993 DOI: 10.1074/jbc.M414139200  0.6
2005 Lemon SM, Yi M, Li K. "Strong reasons make strong actions"--The antiviral efficacy of NS3/4A protease inhibitors Hepatology (Baltimore, Md.). 41: 671-674. PMID 15723328  0.6
2005 Foy E, Li K, Sumpter R, Loo YM, Johnson CL, Wang C, Fish PM, Yoneyama M, Fujita T, Lemon SM, Gale M. Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 2986-91. PMID 15710892 DOI: 10.1073/pnas.0408707102  0.6
2005 Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proceedings of the National Academy of Sciences of the United States of America. 102: 2992-7. PMID 15710891 DOI: 10.1073/pnas.0408824102  0.6
2005 Sumpter R, Loo YM, Foy E, Li K, Yoneyama M, Fujita T, Lemon SM, Gale M. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. Journal of Virology. 79: 2689-99. PMID 15708988 DOI: 10.1128/JVI.79.5.2689-2699.2005  0.6
2005 Locarnini S, Shaw T, Dean J, Colledge D, Thompson A, Li K, Lemon SM, Lau GG, Beard MR. Cellular response to conditional expression of the hepatitis B virus precore and core proteins in cultured hepatoma (Huh-7) cells. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 32: 113-21. PMID 15653413 DOI: 10.1016/j.jcv.2004.10.002  0.6
2004 Bigger CB, Guerra B, Brasky KM, Hubbard G, Beard MR, Luxon BA, Lemon SM, Lanford RE. Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. Journal of Virology. 78: 13779-92. PMID 15564486 DOI: 10.1128/JVI.78.24.13779-13792.2004  0.6
2004 Rijnbrand R, Thiviyanathan V, Kaluarachchi K, Lemon SM, Gorenstein DG. Mutational and structural analysis of stem-loop IIIc of the hepatitis C virus and GB virus B internal ribosome entry sites Journal of Molecular Biology. 343: 805-817. PMID 15476802 DOI: 10.1016/j.jmb.2004.08.095  0.6
2004 Thiviyanathan V, Yang Y, Kaluarachchi K, Rijnbrand R, Gorenstein DG, Lemon SM. High-resolution structure of a picornaviral internal cis-acting RNA replication element (cre) Proceedings of the National Academy of Sciences of the United States of America. 101: 12688-12693. PMID 15314212 DOI: 10.1073/pnas.0403079101  0.6
2004 Yi M, Lemon SM. Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells Journal of Virology. 78: 7904-7915. PMID 15254163 DOI: 10.1128/JVI.78.15.7904-7915.2004  0.6
2004 Disson O, Haouzi D, Desagher S, Loesch K, Hahne M, Kremer EJ, Jacquet C, Lemon SM, Hibner U, Lerat H. Impaired Clearance of Virus-Infected Hepatocytes in Transgenic Mice Expressing the Hepatitis C Virus Polyprotein Gastroenterology. 126: 859-872. PMID 14988840 DOI: 10.1053/j.gastro.2003.12.005  0.6
2004 Scholle F, Li K, Bodola F, Ikeda M, Luxon BA, Lemon SM. Virus-host cell interactions during hepatitis C virus RNA replication: impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis. Journal of Virology. 78: 1513-24. PMID 14722306 DOI: 10.1128/JVI.78.3.1513-1524.2004  0.6
2004 Yang Y, Rijnbrand R, Watowich S, Lemon SM. Genetic evidence for an interaction between a picornaviral cis-acting RNA replication element and 3CD protein. The Journal of Biological Chemistry. 279: 12659-67. PMID 14711816 DOI: 10.1074/jbc.M312992200  0.6
2004 Wang W, Lahser FC, Yi M, Wright-Minogue J, Xia E, Weber PC, Lemon SM, Malcolm BA. Conserved C-terminal threonine of hepatitis C virus NS3 regulates autoproteolysis and prevents product inhibition. Journal of Virology. 78: 700-9. PMID 14694101 DOI: 10.1128/JVI.78.2.700-709.2004  0.6
2003 Martin A, Bodola F, Sangar DV, Goettge K, Popov V, Rijnbrand R, Lanford RE, Lemon SM. Chronic hepatitis associated with GB virus B persistence in a tamarin after intrahepatic inoculation of synthetic viral RNA. Proceedings of the National Academy of Sciences of the United States of America. 100: 9962-7. PMID 12907703 DOI: 10.1073/pnas.1731505100  0.6
2003 Konan KV, Giddings TH, Ikeda M, Li K, Lemon SM, Kirkegaard K. Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus. Journal of Virology. 77: 7843-55. PMID 12829824 DOI: 10.1128/JVI.77.14.7843-7855.2003  0.6
2003 Lau DT, Ma H, Lemon SM, Doo E, Ghany MG, Miskovsky E, Woods GL, Park Y, Hoofnagle JH. A rapid immunochromatographic assay for hepatitis B virus screening. Journal of Viral Hepatitis. 10: 331-4. PMID 12823602 DOI: 10.1046/j.1365-2893.2003.00418.x  0.6
2003 Foy E, Li K, Wang C, Sumpter R, Ikeda M, Lemon SM, Gale M. Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease Science. 300: 1145-1148. PMID 12702807 DOI: 10.1126/science.1082604  0.6
2003 Yi M, Lemon SM. 3′ nontranslated RNA signals required for replication of hepatitis C virus RNA Journal of Virology. 77: 3557-3568. PMID 12610131 DOI: 10.1128/JVI.77.6.3557-3568.2003  0.6
2003 Yi M, Lemon SM. Structure-function analysis of the 3′ stem-loop of hepatitis C virus genomic RNA and its role in viral RNA replication Rna. 9: 331-345. PMID 12592007 DOI: 10.1261/rna.2144203  0.6
2002 Yi M, Bodola F, Lemon SM. Subgenomic hepatitis C virus replicons inducing expression of a secreted enzymatic reporter protein Virology. 304: 197-210. PMID 12504562 DOI: 10.1006/viro.2002.1652  0.6
2002 Yang Y, Rijnbrand R, McKnight KL, Wimmer E, Paul A, Martin A, Lemon SM. Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14. Journal of Virology. 76: 7485-94. PMID 12097561 DOI: 10.1128/JVI.76.15.7485-7494.2002  0.6
2002 Li K, Prow T, Lemon SM, Beard MR. Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells. Hepatology (Baltimore, Md.). 35: 1237-46. PMID 11981774 DOI: 10.1053/jhep.2002.32968  0.6
2002 Ikeda M, Yi M, Li K, Lemon SM. Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells Journal of Virology. 76: 2997-3006. PMID 11861865 DOI: 10.1128/JVI.76.6.2997-3006.2002  0.6
2002 Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM, Weinman SA. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology. 122: 366-75. PMID 11832451  0.6
2002 Lerat H, Honda M, Beard MR, Loesch K, Sun J, Yang Y, Okuda M, Gosert R, Xiao SY, Weinman SA, Lemon SM. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology. 122: 352-65. PMID 11832450  0.6
2002 Yi M, Lemon SM. Replication of subgenomic hepatitis A virus RNAs expressing firefly luciferase is enhanced by mutations associated with adaptation of virus to growth in cultured cells Journal of Virology. 76: 1171-1180. PMID 11773393  0.6
2001 Sun J, Bodola F, Fan X, Irshad H, Soong L, Lemon SM, Chan TS. Hepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection Journal of Virology. 75: 11992-11998. PMID 11711589 DOI: 10.1128/JVI.75.24.11992-11998.2001  0.6
2001 Rijnbrand R, Bredenbeek PJ, Haasnoot PC, Kieft JS, Spaan WJM, Lemon SM. The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs Rna. 7: 585-597. PMID 11345437 DOI: 10.1017/S1355838201000589  0.6
2001 Dollenmaier G, Mosier SM, Scholle F, Sharma N, McKnight KL, Lemon SM. Membrane-associated respiratory syncytial virus F protein expressed from a human rhinovirus type 14 vector is immunogenic Virology. 281: 216-230. PMID 11277694 DOI: 10.1006/viro.2000.0796  0.6
2001 Kunkel M, Lorinczi M, Rijnbrand R, Lemon SM, Watowich SJ. Self-assembly of nucleocapsid-like particles from recombinant hepatitis C virus core protein. Journal of Virology. 75: 2119-29. PMID 11160716 DOI: 10.1128/JVI.75.5.2119-2129.2001  0.6
2001 Beard MR, Cohen L, Lemon SM, Martin A. Characterization of recombinant hepatitis A virus genomes containing exogenous sequences at the 2A/2B junction. Journal of Virology. 75: 1414-26. PMID 11152515 DOI: 10.1128/JVI.75.3.1414-1426.2001  0.6
2000 Wang TH, Rijnbrand RC, Lemon SM. Core protein-coding sequence, but not core protein, modulates the efficiency of cap-independent translation directed by the internal ribosome entry site of hepatitis C virus. Journal of Virology. 74: 11347-58. PMID 11070035 DOI: 10.1128/JVI.74.23.11347-11358.2000  0.6
2000 Dotzauer A, Gebhardt U, Bieback K, Göttke U, Kracke A, Mages J, Lemon SM, Vallbracht A. Hepatitis A virus-specific immunoglobulin a mediates infection of hepatocytes with hepatitis A virus via the asialoglycoprotein receptor Journal of Virology. 74: 10950-10957. PMID 11069989 DOI: 10.1128/JVI.74.23.10950-10957.2000  0.6
2000 Lerat H, Shimizu YK, Lemon SM. Cell type-specific enhancement of hepatitis C virus internal ribosome entry site-directed translation due to 5' nontranslated region substitutions selected during passage of virus in lymphoblastoid cells Journal of Virology. 74: 7024-7031. PMID 10888641 DOI: 10.1128/JVI.74.15.7024-7031.2000  0.6
2000 Lemon SM, Lerat H, Weinman SA, Honda M. A transgenic mouse model of steatosis and hepatocellular carcinoma associated with chronic hepatitis C virus infection in humans Transactions of the American Clinical and Climatological Association. 111. PMID 10881339  0.6
2000 Blank CA, Anderson DA, Beard M, Lemon SM. Infection of polarized cultures of human intestinal epithelial cells with hepatitis A virus: Vectorial release of progeny virions through apical cellular membranes Journal of Virology. 74: 6476-6484. PMID 10864660 DOI: 10.1128/JVI.74.14.6476-6484.2000  0.6
2000 Yi M, Schultz DE, Lemon SM. Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function. Journal of Virology. 74: 6459-68. PMID 10864658 DOI: 10.1128/JVI.74.14.6459-6468.2000  0.6
2000 Bertolino P, Klimpel G, Lemon SM. Hepatic inflammation and immunity: A summary of a conference on the function of the immune system within the liver Hepatology. 31: 1374-1378. PMID 10827166  0.6
2000 Honda M, Kaneko S, Shimazaki T, Matsushita E, Kobayashi K, Ping LH, Zhang HC, Lemon SM. Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells. Hepatology (Baltimore, Md.). 31: 1351-9. PMID 10827163 DOI: 10.1053/jhep.2000.7985  0.6
2000 Butkiewicz N, Yao N, Zhong W, Wright-Minogue J, Ingravallo P, Zhang R, Durkin J, Standring DN, Baroudy BM, Sangar DV, Lemon SM, Lau JYN, Hong Z. Virus-specific cofactor requirement and chimeric hepatitis C virus/GB virus B nonstructural protein 3 Journal of Virology. 74: 4291-4301. PMID 10756044 DOI: 10.1128/JVI.74.9.4291-4301.2000  0.6
2000 Lemon SM, Layden TJ, Seeff L, Suzuki H, Nishioka K, Mishiro S, Johnson L. The 20th United States-Japan joint hepatitis panel meeting Hepatology. 31: 800-806. PMID 10706578  0.6
2000 Gosert R, Chang KH, Rijnbrand R, Yi M, Sangar DV, Lemon SM. Transient expression of cellular polypyrimidine-tract binding protein stimulates cap-independent translation directed by both picornaviral and flaviviral internal ribosome entry sites in vivo Molecular and Cellular Biology. 20: 1583-1595. PMID 10669736 DOI: 10.1128/MCB.20.5.1583-1595.2000  0.6
2000 Rijnbrand R, Abell G, Lemon SM. Mutational analysis of the GB virus B internal ribosome entry site Journal of Virology. 74: 773-783. PMID 10623739 DOI: 10.1128/JVI.74.2.773-783.2000  0.6
2000 Honda M, Kaneko S, Matsushita E, Kobayashi K, Abell GA, Lemon SM. Cell cycle regulation of hepatitis C virus internal ribosomal entry site-directed translation Gastroenterology. 118: 152-162. PMID 10611164  0.6
2000 Rijnbrand RCA, Lemon SM. Internal ribosome entry site-mediated translation in hepatitis C virus replication Current Topics in Microbiology and Immunology. 242: 85-116. PMID 10592657  0.6
1999 Lemon SM. Current status of antiviral therapy for chronic hepatitis C Advances in Experimental Medicine and Biology. 458: 29-37. PMID 10549377  0.6
1999 Martin A, Bénichou D, Chao SF, Cohen LM, Lemon SM. Maturation of the hepatitis A virus capsid protein VP1 is not dependent on processing by the 3Cpro proteinase. Journal of Virology. 73: 6220-7. PMID 10400711  0.6
1999 Beard MR, Abell G, Honda M, Carroll A, Gartland M, Clarke B, Suzuki K, Lanford R, Sangar DV, Lemon SM. An infectious molecular clone of a Japanese genotype 1b hepatitis C virus. Hepatology (Baltimore, Md.). 30: 316-24. PMID 10385673 DOI: 10.1002/hep.510300137  0.6
1999 Honda M, Rijnbrand R, Abell G, Kim D, Lemon SM. Natural variation in translational activities of the 5' nontranslated RNAs of hepatitis C virus genotypes 1a and 1b: Evidence for a long-range RNA- RNA interaction outside of the internal ribosomal entry site Journal of Virology. 73: 4941-4951. PMID 10233956  0.6
1999 Funkhouser AW, Schultz DE, Lemon SM, Purcell RH, Emerson SU. Hepatitis A virus translation is rate-limiting for virus replication in MRC-5 cells. Virology. 254: 268-78. PMID 9986793 DOI: 10.1006/viro.1998.9548  0.6
1999 Honda M, Beard MR, Ping LH, Lemon SM. A phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation. Journal of Virology. 73: 1165-74. PMID 9882318  0.6
1999 Hardin CC, Sneeden JL, Lemon SM, Brown BA, Guenther RH, Sierzputowska-Gracz H. Folding of pyrimidine-enriched RNA fragments from the vicinity of the internal ribosomal entry site of hepatitis A virus. Nucleic Acids Research. 27: 665-73. PMID 9862995 DOI: 10.1093/nar/27.2.665  0.6
1999 Maddrey WC, Lemon SM, Johnson LD. Introduction American Journal of Medicine. 107: 1.  0.6
1999 McGinnis MR, Lemon SM, Walker DH, De Hoog GS, Haase G. Fatal cerebritis caused by a new species of Cladophialophora Studies in Mycology. 1999: 166-171.  0.6
1998 Mcknight KL, Lemon SM. The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication Rna. 4: 1569-1584. PMID 9848654 DOI: 10.1017/S1355838298981006  0.6
1998 Lemon SM, Chisari FV, Lai MMC, Nishioka K, Mishiro S, Johnson L. The nineteenth United States-Japan Joint Hepatitis Panel Meeting Hepatology. 28: 881-887. PMID 9731586  0.6
1998 Zuccola HJ, Rozzelle JE, Lemon SM, Erickson BW, Hogle JM. Structural basis of the oligomerization of hepatitis delta antigen. Structure (London, England : 1993). 6: 821-30. PMID 9687364  0.6
1998 Martinson FEA, Weigle KA, Royce RA, Weber DJ, Suchindran CM, Lemon SM. Risk factors for horizontal transmission of hepatitis B virus in a rural district in Ghana American Journal of Epidemiology. 147: 478-487. PMID 9525535  0.6
1997 Lemon SM. Type A viral hepatitis: Epidemiology, diagnosis, and prevention Clinical Chemistry. 43: 1494-1499. PMID 9265900  0.6
1997 Lemon SM, Murphy PC, Provost PJ, Chalikonda I, Davide JP, Schofield TL, Nalin DR, Lewis JA. Immunoprecipitation and virus neutralization assays demonstrate qualitative differences between protective antibody responses to inactivated hepatitis A vaccine and passive immunization with immune globulin Journal of Infectious Diseases. 176: 9-19. PMID 9207344  0.6
1997 Milstien JB, Lemon SM, Wright PF. Development of a more thermostable poliovirus vaccine Journal of Infectious Diseases. 175. PMID 9203724  0.6
1997 Lemon SM, Nishioka K, Mishiro S, Johnson L. The 18th United States-Japan Joint Hepatitis Panel Meeting Hepatology (Baltimore, Md.). 25: 1287-1291. PMID 9141456  0.6
1997 Theodore D, Lemon SM. GB virus C, hepatitis G virus, or human orphan flavivirus? Hepatology. 25: 1285-1286. PMID 9141455  0.6
1997 Lemon SM, Thomas DL. Vaccines to prevent viral hepatitis New England Journal of Medicine. 336: 196-204. PMID 8988900 DOI: 10.1056/NEJM199701163360307  0.6
1997 Lemon SM, Honda M. Internal ribosome entry sites within the RNA genomes of hepatitis C virus and other flaviviruses Seminars in Virology. 8: 274-288. DOI: 10.1006/smvy.1997.0129  0.6
1996 Honda M, Brown EA, Lemon SM. Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA Rna. 2: 955-968. PMID 8849773  0.6
1996 Honda M, Ping LH, Rijnbrand RCA, Amphlett E, Clarke B, Rowlands D, Lemon SM. Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA Virology. 222: 31-42. PMID 8806485 DOI: 10.1006/viro.1996.0395  0.6
1996 Simons JN, Desai SM, Schultz DE, Lemon SM, Mushahwar IK. Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization. Journal of Virology. 70: 6126-35. PMID 8709237  0.6
1996 Bichko VV, Lemon SM, Wang JG, Hwang S, Lai MM, Taylor JM. Epitopes exposed on hepatitis delta virus ribonucleoproteins. Journal of Virology. 70: 5807-11. PMID 8709197  0.6
1996 Schultz DE, Hardin CC, Lemon SM. Specific interaction of glyceraldehyde 3-phosphate dehydrogenase with the 5'-nontranslated RNA of hepatitis A virus. The Journal of Biological Chemistry. 271: 14134-42. PMID 8662893  0.6
1996 Schultz DE, Honda M, Whetter LE, McKnight KL, Lemon SM. Mutations within the 5' nontranslated RNA of cell culture-adapted hepatitis A virus which enhance cap-independent translation in cultured African green monkey kidney cells. Journal of Virology. 70: 1041-9. PMID 8551562  0.6
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