Nels C. Elde, Ph.D. - Publications

Affiliations: 
Human Genetics University of Utah, Salt Lake City, UT 
Area:
host-viral evolution, membrane trafficking
Website:
http://cellvolution.org

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Goldstein SA, Elde NC. Recurrent viral capture of cellular phosphodiesterases that antagonize OAS-RNase L. Proceedings of the National Academy of Sciences of the United States of America. 121: e2312691121. PMID 38277437 DOI: 10.1073/pnas.2312691121  0.33
2023 Goldstein SA, Feeley TM, Babler KM, Hilbert ZA, Downhour DM, Moshiri N, Elde NC. Hidden evolutionary constraints dictate the retention of coronavirus accessory genes. Biorxiv : the Preprint Server For Biology. PMID 37873270 DOI: 10.1101/2023.10.12.561935  0.365
2023 Goldstein SA, Elde NC. Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L. Biorxiv : the Preprint Server For Biology. PMID 37745432 DOI: 10.1101/2023.05.12.540623  0.329
2023 Hilbert ZA, Bednarek JM, Schwiesow MJW, Chung KY, Moreau CT, Brown JCS, Elde NC. Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity. Current Biology : Cb. 33: 4136-4149.e9. PMID 37708888 DOI: 10.1016/j.cub.2023.08.054  0.313
2023 Boys IN, Johnson AG, Quinlan MR, Kranzusch PJ, Elde NC. Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity. Cell Reports. 42: 112878. PMID 37494187 DOI: 10.1016/j.celrep.2023.112878  0.326
2023 Hilbert ZA, Haffener PE, Young HJ, Schwiesow MJW, Leffler EM, Elde NC. Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host-Microbe Arms Races beyond Canonical Protein-Protein Interfaces. Genome Biology and Evolution. 15. PMID 37390614 DOI: 10.1093/gbe/evad119  0.324
2023 Boys IN, Johnson AG, Quinlan M, Kranzusch PJ, Elde NC. Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses. Biorxiv : the Preprint Server For Biology. PMID 36909515 DOI: 10.1101/2023.02.26.529821  0.351
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Elde N, et al. Virology under the Microscope-a Call for Rational Discourse. Msphere. e0003423. PMID 36700653 DOI: 10.1128/msphere.00034-23  0.641
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Elde N, et al. Virology under the Microscope-a Call for Rational Discourse. Mbio. e0018823. PMID 36700642 DOI: 10.1128/mbio.00188-23  0.641
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Elde N, et al. Virology under the Microscope-a Call for Rational Discourse. Journal of Virology. e0008923. PMID 36700640 DOI: 10.1128/jvi.00089-23  0.641
2022 Goldstein SA, Brown J, Pedersen BS, Quinlan AR, Elde NC. Extensive Recombination-driven Coronavirus Diversification Expands the Pool of Potential Pandemic Pathogens. Genome Biology and Evolution. 14. PMID 36477201 DOI: 10.1093/gbe/evac161  0.315
2022 Jacquet S, Culbertson M, Zhang C, El Filali A, De La Myre Mory C, Pons JB, Filippi-Codaccioni O, Lauterbur ME, Ngoubangoye B, Duhayer J, Verez C, Park C, Dahoui C, Carey CM, Brennan G, ... ... Elde NC, et al. Adaptive duplication and genetic diversification of protein kinase R contribute to the specificity of bat-virus interactions. Science Advances. 8: eadd7540. PMID 36417524 DOI: 10.1126/sciadv.add7540  0.374
2022 Fixsen SM, Cone KR, Goldstein SA, Sasani TA, Quinlan AR, Rothenburg S, Elde NC. Poxviruses capture host genes by LINE-1 retrotransposition. Elife. 11. PMID 36069526 DOI: 10.7554/eLife.63332  0.695
2022 Rheinemann L, Downhour DM, Davenport KA, McKeown AN, Sundquist WI, Elde NC. Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates. Current Biology : Cb. PMID 35245459 DOI: 10.1016/j.cub.2022.02.018  0.325
2021 Goldstein SA, Brown J, Pedersen BS, Quinlan AR, Elde NC. Extensive recombination-driven coronavirus diversification expands the pool of potential pandemic pathogens. Biorxiv : the Preprint Server For Biology. PMID 33564759 DOI: 10.1101/2021.02.03.429646  0.309
2020 Sorouri M, Chang T, Jesudhasan P, Pinkham C, Elde NC, Hancks DC. Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network. Plos Biology. 18: e3001045. PMID 33370271 DOI: 10.1371/journal.pbio.3001045  0.711
2020 Balla KM, Rice MC, Gagnon JA, Elde NC. Linking Virus Discovery to Immune Responses Visualized during Zebrafish Infections. Current Biology : Cb. PMID 32413307 DOI: 10.1016/J.Cub.2020.04.031  0.461
2019 Carey CM, Govande AA, Cooper JM, Hartley MK, Kranzusch PJ, Elde NC. Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates. Cell Host & Microbe. PMID 30713099 DOI: 10.1016/J.Chom.2019.01.001  0.373
2018 Sasani TA, Cone KR, Quinlan AR, Elde NC. Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays. Elife. 7. PMID 30156554 DOI: 10.7554/Elife.35453  0.694
2018 Sasani TA, Cone KR, Quinlan AR, Elde NC. Author response: Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays Elife. DOI: 10.7554/Elife.35453.045  0.336
2017 Barber MF, Lee EM, Griffin H, Elde NC. Rapid Evolution of Primate Type 2 Immune Response Factors Linked to Asthma Susceptibility. Genome Biology and Evolution. 9: 1757-1765. PMID 28854632 DOI: 10.1093/Gbe/Evx120  0.385
2016 Cone KR, Kronenberg ZN, Yandell M, Elde NC. Emergence of a viral RNA polymerase variant during gene copy number amplification promotes rapid evolution of vaccinia virus. Journal of Virology. PMID 27928012 DOI: 10.1128/Jvi.01428-16  0.712
2016 Chuong EB, Elde NC, Feschotte C. Regulatory activities of transposable elements: from conflicts to benefits. Nature Reviews. Genetics. PMID 27867194 DOI: 10.1038/Nrg.2016.139  0.74
2016 Yu Y, Yarrington RM, Chuong EB, Elde NC, Stillman DJ. Disruption of promoter memory by synthesis of a long noncoding RNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506791 DOI: 10.1073/Pnas.1601793113  0.669
2016 Barber MF, Kronenberg Z, Yandell M, Elde NC. Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans. Plos Genetics. 12: e1006063. PMID 27203426 DOI: 10.1371/Journal.Pgen.1006063  0.389
2016 Chuong EB, Elde NC, Feschotte C. Regulatory evolution of innate immunity through co-option of endogenous retroviruses. Science (New York, N.Y.). 351: 1083-7. PMID 26941318 DOI: 10.1126/Science.Aad5497  0.755
2015 Kronenberg ZN, Osborne EJ, Cone KR, Kennedy BJ, Domyan ET, Shapiro MD, Elde NC, Yandell M. Wham: Identifying Structural Variants of Biological Consequence. Plos Computational Biology. 11: e1004572. PMID 26625158 DOI: 10.1371/Journal.Pcbi.1004572  0.659
2015 Barber MF, Elde NC. Buried Treasure: Evolutionary Perspectives on Microbial Iron Piracy. Trends in Genetics : Tig. 31: 627-36. PMID 26431675 DOI: 10.1016/J.Tig.2015.09.001  0.35
2015 Hancks DC, Hartley MK, Hagan C, Clark NL, Elde NC. Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape. Plos Genetics. 11: e1005203. PMID 25942676 DOI: 10.1371/Journal.Pgen.1005203  0.749
2015 Orzalli MH, Broekema NM, Diner BA, Hancks DC, Elde NC, Cristea IM, Knipe DM. cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection. Proceedings of the National Academy of Sciences of the United States of America. 112: E1773-81. PMID 25831530 DOI: 10.1073/Pnas.1424637112  0.707
2015 DePaula-Silva AB, Cassiday PA, Chumley J, Bosque A, Monteiro-Filho CM, Mahon CS, Cone KR, Krogan N, Elde NC, Planelles V. Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr. Virology. 477: 10-7. PMID 25618414 DOI: 10.1016/J.Virol.2014.12.040  0.62
2014 Barber MF, Elde NC. Nutritional immunity. Escape from bacterial iron piracy through rapid evolution of transferrin. Science (New York, N.Y.). 346: 1362-6. PMID 25504720 DOI: 10.1126/Science.1259329  0.346
2013 Barber MF, Elde NC. Evolutionary biology: Mimicry all the way down. Nature. 501: 38-9. PMID 24005409 DOI: 10.1038/501038A  0.365
2012 Elde NC. Poliovirus evolution: the strong, silent type. Cell Host & Microbe. 12: 605-6. PMID 23159048 DOI: 10.1016/J.Chom.2012.11.002  0.35
2012 Elde NC, Child SJ, Eickbush MT, Kitzman JO, Rogers KS, Shendure J, Geballe AP, Malik HS. Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses. Cell. 150: 831-41. PMID 22901812 DOI: 10.1016/J.Cell.2012.05.049  0.649
2012 Sawyer SL, Elde NC. A cross-species view on viruses. Current Opinion in Virology. 2: 561-8. PMID 22835485 DOI: 10.1016/J.Coviro.2012.07.003  0.623
2011 Elde NC, Roach KC, Yao MC, Malik HS. Absence of positive selection on centromeric histones in Tetrahymena suggests unsuppressed centromere: drive in lineages lacking male meiosis. Journal of Molecular Evolution. 72: 510-20. PMID 21643829 DOI: 10.1007/S00239-011-9449-0  0.639
2009 Elde NC, Malik HS. The evolutionary conundrum of pathogen mimicry. Nature Reviews. Microbiology. 7: 787-97. PMID 19806153 DOI: 10.1038/Nrmicro2222  0.617
2009 Elde NC, Child SJ, Geballe AP, Malik HS. Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature. 457: 485-9. PMID 19043403 DOI: 10.1038/Nature07529  0.618
2008 Rahaman A, Elde NC, Turkewitz AP. A dynamin-related protein required for nuclear remodeling in Tetrahymena. Current Biology : Cb. 18: 1227-33. PMID 18701286 DOI: 10.1016/J.Cub.2008.07.042  0.332
2007 Elde NC, Long M, Turkewitz AP. A role for convergent evolution in the secretory life of cells. Trends in Cell Biology. 17: 157-64. PMID 17329106 DOI: 10.1016/J.Tcb.2007.02.007  0.34
2006 Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, ... ... Elde NC, et al. Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. Plos Biology. 4: e286. PMID 16933976 DOI: 10.1371/Journal.Pbio.0040286  0.403
2005 Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP. Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. Plos Genetics. 1: e52. PMID 16276403 DOI: 10.1371/Journal.Pgen.0010052  0.361
2001 Chilcoat ND, Elde NC, Turkewitz AP. An antisense approach to phenotype-based gene cloning in Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America. 98: 8709-13. PMID 11438705 DOI: 10.1073/Pnas.151243498  0.365
Show low-probability matches.