| Year |
Citation |
Score |
| 2021 |
Wang Y, Minden A. The Use of Nanomedicine to Target Signaling by the PAK Kinases for Disease Treatment. Cells. 10. PMID 34944073 DOI: 10.3390/cells10123565 |
0.404 |
|
| 2019 |
Cordover E, Wei J, Patel C, Shan NL, Gionco J, Sargsyan D, Wu R, Cai L, Tony Kong AN, Jacinto E, Minden A. KPT-9274, an inhibitor of PAK4 and NAMPT, leads to downregulation of mTORC2 in triple negative breast cancer cells. Chemical Research in Toxicology. PMID 31876149 DOI: 10.1021/Acs.Chemrestox.9B00376 |
0.352 |
|
| 2018 |
Rane CK, Minden A. P21 activated kinase signaling in cancer. Seminars in Cancer Biology. PMID 29330094 DOI: 10.1016/j.semcancer.2018.01.006 |
0.386 |
|
| 2018 |
Chaker M, Minden A, Chen S, Weiss RH, Chini EN, Mahipal A, Azmi AS. Rho GTPase effectors and NAD metabolism in cancer immune suppression. Expert Opinion On Therapeutic Targets. 22: 9-17. PMID 29207896 DOI: 10.1080/14728222.2018.1413091 |
0.308 |
|
| 2018 |
Sampat N, Minden A. Inhibitors of the p21 Activated Kinases Current Pharmacology Reports. 4: 238-249. DOI: 10.1007/s40495-018-0132-7 |
0.39 |
|
| 2017 |
Rane CK, Patel M, Cai L, Senapedis W, Baloglu E, Minden A. Decrypting the PAK4 transcriptome profile in mammary tumor forming cells using Next Generation Sequencing. Genomics. PMID 29055713 DOI: 10.1016/J.Ygeno.2017.10.004 |
0.319 |
|
| 2014 |
Rane CK, Minden A. P21 activated kinases: structure, regulation, and functions. Small Gtpases. 5. PMID 24658305 DOI: 10.4161/sgtp.28003 |
0.505 |
|
| 2012 |
Minden A. PAK4-6 in cancer and neuronal development. Cellular Logistics. 2: 95-104. PMID 23125951 DOI: 10.4161/cl.21171 |
0.319 |
|
| 2012 |
Coste O, Möser CV, Sisignano M, Kynast KL, Minden A, Geisslinger G, Niederberger E. The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors. Behavioural Brain Research. 234: 121-8. PMID 22732262 DOI: 10.1016/j.bbr.2012.06.017 |
0.348 |
|
| 2012 |
Strochlic TI, Concilio S, Viaud J, Eberwine RA, Wong LE, Minden A, Turk BE, Plomann M, Peterson JR. Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking. Proceedings of the National Academy of Sciences of the United States of America. 109: 4116-21. PMID 22371566 DOI: 10.1073/Pnas.1116560109 |
0.309 |
|
| 2011 |
Nekrasova T, Minden A. PAK4 is required for regulation of the cell-cycle regulatory protein p21, and for control of cell-cycle progression. Journal of Cellular Biochemistry. 112: 1795-806. PMID 21381077 DOI: 10.1002/jcb.23092 |
0.356 |
|
| 2010 |
Liu Y, Chen N, Cui X, Zheng X, Deng L, Price S, Karantza V, Minden A. The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis Oncogene. 29: 5883-5894. PMID 20697354 DOI: 10.1038/onc.2010.329 |
0.38 |
|
| 2010 |
Wong LE, Reynolds AB, Dissanayaka NT, Minden A. p120-catenin is a binding partner and substrate for Group B Pak kinases. Journal of Cellular Biochemistry. 110: 1244-54. PMID 20564219 DOI: 10.1002/Jcb.22639 |
0.433 |
|
| 2009 |
Tian Y, Lei L, Cammarano M, Nekrasova T, Minden A. Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mechanisms of Development. 126: 710-20. PMID 19464366 DOI: 10.1016/J.Mod.2009.05.002 |
0.667 |
|
| 2008 |
Nekrasova T, Jobes ML, Ting JH, Wagner GC, Minden A. Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion. Developmental Biology. 322: 95-108. PMID 18675265 DOI: 10.1016/J.Ydbio.2008.07.006 |
0.322 |
|
| 2008 |
Liu Y, Xiao H, Tian Y, Nekrasova T, Hao X, Lee HJ, Suh N, Yang CS, Minden A. The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice. Molecular Cancer Research : McR. 6: 1215-24. PMID 18644984 DOI: 10.1158/1541-7786.Mcr-08-0087 |
0.439 |
|
| 2006 |
Gringel A, Walz D, Rosenberger G, Minden A, Kutsche K, Kopp P, Linder S. PAK4 and alphaPIX determine podosome size and number in macrophages through localized actin regulation. Journal of Cellular Physiology. 209: 568-79. PMID 16897755 DOI: 10.1002/jcp.20777 |
0.482 |
|
| 2005 |
Li X, Minden A. PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor. The Journal of Biological Chemistry. 280: 41192-200. PMID 16227624 DOI: 10.1074/jbc.M506884200 |
0.53 |
|
| 2005 |
Cammarano MS, Nekrasova T, Noel B, Minden A. Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling. Molecular and Cellular Biology. 25: 9532-42. PMID 16227603 DOI: 10.1128/Mcb.25.21.9532-9542.2005 |
0.715 |
|
| 2005 |
Berzat AC, Buss JE, Chenette EJ, Weinbaum CA, Shutes A, Der CJ, Minden A, Cox AD. Transforming activity of the Rho family GTPase, Wrch-1, a Wnt-regulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif. The Journal of Biological Chemistry. 280: 33055-65. PMID 16046391 DOI: 10.1074/Jbc.M507362200 |
0.327 |
|
| 2003 |
Gnesutta N, Minden A. Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4. Molecular and Cellular Biology. 23: 7838-48. PMID 14560027 DOI: 10.1128/Mcb.23.21.7838-7848.2003 |
0.528 |
|
| 2003 |
Li X, Minden A. Targeted disruption of the gene for the PAK5 kinase in mice. Molecular and Cellular Biology. 23: 7134-42. PMID 14517284 DOI: 10.1128/Mcb.23.20.7134-7142.2003 |
0.477 |
|
| 2003 |
Qu J, Li X, Novitch BG, Zheng Y, Kohn M, Xie JM, Kozinn S, Bronson R, Beg AA, Minden A. PAK4 kinase is essential for embryonic viability and for proper neuronal development. Molecular and Cellular Biology. 23: 7122-33. PMID 14517283 DOI: 10.1128/Mcb.23.20.7122-7133.2003 |
0.442 |
|
| 2002 |
Liberto M, Cobrinik D, Minden A. Rho regulates p21(CIP1), cyclin D1, and checkpoint control in mammary epithelial cells. Oncogene. 21: 1590-9. PMID 11896588 DOI: 10.1038/Sj.Onc.1205242 |
0.457 |
|
| 2002 |
Dan C, Nath N, Liberto M, Minden A. PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells. Molecular and Cellular Biology. 22: 567-77. PMID 11756552 DOI: 10.1128/MCB.22.2.567-577.2002 |
0.541 |
|
| 2001 |
Bouzahzah B, Albanese C, Ahmed F, Pixley F, Lisanti MP, Segall JD, Condeelis J, Joyce D, Minden A, Der CJ, Chan A, Symons M, Pestell RG. Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Molecular Medicine (Cambridge, Mass.). 7: 816-30. PMID 11844870 |
0.361 |
|
| 2001 |
Dan C, Kelly A, Bernard O, Minden A. Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin. The Journal of Biological Chemistry. 276: 32115-21. PMID 11413130 DOI: 10.1074/jbc.M100871200 |
0.556 |
|
| 2001 |
Cammarano MS, Minden A. Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways. The Journal of Biological Chemistry. 276: 25876-82. PMID 11337492 DOI: 10.1074/Jbc.M011345200 |
0.681 |
|
| 2001 |
Qu J, Cammarano MS, Shi Q, Ha KC, de Lanerolle P, Minden A. Activated PAK4 regulates cell adhesion and anchorage-independent growth. Molecular and Cellular Biology. 21: 3523-33. PMID 11313478 DOI: 10.1128/Mcb.21.10.3523-3533.2001 |
0.719 |
|
| 2001 |
Gnesutta N, Qu J, Minden A. The Serine/Threonine Kinase PAK4 Prevents Caspase Activation and Protects Cells from Apoptosis Journal of Biological Chemistry. 276: 14414-14419. PMID 11278822 |
0.551 |
|
| 2001 |
Bouzahzah B, Albanese C, Ahmed F, Pixley F, Lisanti MP, Segall JD, Condeelis J, Joyce D, Minden A, Der CJ, Chan A, Symons M, Pestell RG. Rho Family GTPases Regulate Mammary Epithelium Cell Growth and Metastasis Through Distinguishable Pathways Molecular Medicine. 7: 816-830. DOI: 10.1007/Bf03401974 |
0.478 |
|
| 2000 |
Tashiro A, Minden A, Yuste R. Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho. Cerebral Cortex (New York, N.Y. : 1991). 10: 927-38. PMID 11007543 DOI: 10.1093/Cercor/10.10.927 |
0.389 |
|
| 1999 |
Wang S, Nath N, Minden A, Chellappan S. Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases. The Embo Journal. 18: 1559-70. PMID 10075927 DOI: 10.1093/Emboj/18.6.1559 |
0.57 |
|
| 1998 |
Abo A, Qu J, Cammarano MS, Dan C, Fritsch A, Baud V, Belisle B, Minden A. PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia. The Embo Journal. 17: 6527-40. PMID 9822598 DOI: 10.1093/Emboj/17.22.6527 |
0.701 |
|
| 1998 |
Clarke N, Arenzana N, Hai T, Minden A, Prywes R. Epidermal growth factor induction of the c-jun promoter by a Rac pathway. Molecular and Cellular Biology. 18: 1065-73. PMID 9448004 DOI: 10.1128/Mcb.18.2.1065 |
0.461 |
|
| 1997 |
Minden A, Karin M. Regulation and function of the JNK subgroup of MAP kinases Biochimica Et Biophysica Acta - Reviews On Cancer. 1333. PMID 9395283 DOI: 10.1016/S0304-419X(97)00018-8 |
0.428 |
|
| 1997 |
Kuroki DW, Minden A, Sánchez I, Wattenberg EV. Regulation of a c-Jun amine-terminal kinase/stress-activated protein kinase cascade by a sodium-dependent signal transduction pathway Journal of Biological Chemistry. 272: 23905-23911. PMID 9295340 DOI: 10.1074/Jbc.272.38.23905 |
0.514 |
|
| 1996 |
Collins LR, Minden A, Karin M, Brown JH. Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac. The Journal of Biological Chemistry. 271: 17349-53. PMID 8663428 DOI: 10.1074/jbc.271.29.17349 |
0.417 |
|
| 1996 |
Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. The Journal of Biological Chemistry. 271: 3229-37. PMID 8621725 DOI: 10.1074/Jbc.271.6.3229 |
0.558 |
|
| 1995 |
Lin A, Minden A, Martinetto H, Claret FX, Lange-Carter C, Mercurio F, Johnson GL, Karin M. Identification of a dual specificity kinase that activates the jun kinases and p38-Mpk2 Science. 268: 286-290. PMID 7716521 DOI: 10.1126/Science.7716521 |
0.509 |
|
| 1995 |
Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs Cell. 81: 1147-1157. PMID 7600582 DOI: 10.1016/S0092-8674(05)80019-4 |
0.497 |
|
| 1994 |
Minden A, Lin A, McMahon M, Lange-Carter C, Dérijard B, Davis RJ, Johnson GL, Karin M. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK Science. 266: 1719-1723. PMID 7992057 DOI: 10.1126/Science.7992057 |
0.47 |
|
| 1994 |
Minden A, Lin A, Smeal T, Dérijard B, Cobb M, Davis R, Karin M. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases Molecular and Cellular Biology. 14: 6683-6688. PMID 7935387 DOI: 10.1128/mcb.14.10.6683-6688.1994 |
0.386 |
|
| 1994 |
Westwick JK, Weitzel C, Minden A, Karin M, Brenner DA. Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase Journal of Biological Chemistry. 269: 26396-26401. PMID 7929360 |
0.477 |
|
| 1993 |
Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain Genes and Development. 7: 2135-2148. PMID 8224842 DOI: 10.1101/Gad.7.11.2135 |
0.399 |
|
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