Gary R. Klimpel - Publications

University of Texas Medical Branch, Galveston, TX 
Immunology, Microbiology Biology, Cell Biology

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Peterson JW, Moen ST, Healy D, Pawlik JE, Taormina J, Hardcastle J, Thomas JM, Lawrence WS, Ponce C, Chatuev BM, Gnade BT, Foltz SM, Agar SL, Sha J, Klimpel GR, et al. Protection Afforded by Fluoroquinolones in Animal Models of Respiratory Infections with Bacillus anthracis, Yersinia pestis, and Francisella tularensis. The Open Microbiology Journal. 4: 34-46. PMID 21127743 DOI: 10.2174/1874285801004010034  0.304
2010 Tuero I, Vinetz JM, Klimpel GR. Lack of demonstrable memory T cell responses in humans who have spontaneously recovered from leptospirosis in the Peruvian Amazon. The Journal of Infectious Diseases. 201: 420-7. PMID 20053135 DOI: 10.1086/650300  0.373
2010 Evans SE, Scott BL, Clement CG, Larson DT, Kontoyiannis D, Lewis RE, Lasala PR, Pawlik J, Peterson JW, Chopra AK, Klimpel G, Bowden G, Höök M, Xu Y, Tuvim MJ, et al. Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi. American Journal of Respiratory Cell and Molecular Biology. 42: 40-50. PMID 19329554 DOI: 10.1165/Rcmb.2008-0260Oc  0.368
2010 Telepnev MV, Klimpel GR, Haithcoat J, Knirel YA, Anisimov AP, Motin V. Erratum: Tetraacylated lipopolysaccharide of Yersinia pestis can inhibit multiple Toll-like receptor-mediated signaling pathways in human dendritic cells. (Journal of Infectious Diseases (2009) 200 (1694-1702)) The Journal of Infectious Diseases. 201. DOI: 10.1086/650382  0.312
2009 Endsley JJ, Torres AG, Gonzales CM, Kosykh VG, Motin VL, Peterson JW, Estes DM, Klimpel GR. Comparative antimicrobial activity of granulysin against bacterial biothreat agents. The Open Microbiology Journal. 3: 92-6. PMID 19587798 DOI: 10.2174/1874285800903010092  0.325
2008 Klimpel GR, Eaves-Pyles T, Moen ST, Taormina J, Peterson JW, Chopra AK, Niesel DW, Carness P, Haithcoat JL, Kirtley M, Nasr AB. Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody. Vaccine. 26: 6874-82. PMID 18930100 DOI: 10.1016/J.Vaccine.2008.09.077  0.358
2008 Ben Nasr A, Klimpel GR. Subversion of complement activation at the bacterial surface promotes serum resistance and opsonophagocytosis of Francisella tularensis. Journal of Leukocyte Biology. 84: 77-85. PMID 18430786 DOI: 10.1096/Fasebj.22.2_Supplement.548  0.303
2008 Liu T, König R, Sha J, Agar SL, Tseng CT, Klimpel GR, Chopra AK. Immunological responses against Salmonella enterica serovar Typhimurium Braun lipoprotein and lipid A mutant strains in Swiss-Webster mice: potential use as live-attenuated vaccines. Microbial Pathogenesis. 44: 224-37. PMID 17997275 DOI: 10.1016/J.Micpath.2007.09.005  0.414
2007 Gentry M, Taormina J, Pyles RB, Yeager L, Kirtley M, Popov VL, Klimpel G, Eaves-Pyles T. Role of primary human alveolar epithelial cells in host defense against Francisella tularensis infection. Infection and Immunity. 75: 3969-78. PMID 17502386 DOI: 10.1128/Iai.00157-07  0.405
2006 Ben Nasr A, Haithcoat J, Masterson JE, Gunn JS, Eaves-Pyles T, Klimpel GR. Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria. Journal of Leukocyte Biology. 80: 774-86. PMID 16857732 DOI: 10.1189/Jlb.1205755  0.389
2005 Fadl AA, Sha J, Klimpel GR, Olano JP, Niesel DW, Chopra AK. Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar typhimurium systemic infection Infection and Immunity. 73: 1081-1096. PMID 15664952 DOI: 10.1128/Iai.73.2.1081-1096.2005  0.398
2004 Sha J, Fadl AA, Klimpel GR, Niesel DW, Popov VL, Chopra AK. The two murein lipoproteins of Salmonella enterica serovar typhimurium contribute to the virulence of the organism Infection and Immunity. 72: 3987-4003. PMID 15213144 DOI: 10.1128/Iai.72.7.3987-4003.2004  0.417
2003 Klimpel GR, Matthias MA, Vinetz JM. Leptospira interrogans activation of human peripheral blood mononuclear cells: preferential expansion of TCR gamma delta+ T cells vs TCR alpha beta+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 1447-55. PMID 12874237 DOI: 10.4049/Jimmunol.171.3.1447  0.431
2002 Tseng CT, Klimpel GR. Binding of the hepatitis C virus envelope protein E2 to CD81 inhibits natural killer cell functions. The Journal of Experimental Medicine. 195: 43-9. PMID 11781364 DOI: 10.1084/Jem.20011145  0.399
2001 Bassett SE, Guerra B, Brasky K, Miskovsky E, Houghton M, Klimpel GR, Lanford RE. Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection Hepatology. 33: 1479-1487. PMID 11391537 DOI: 10.1053/Jhep.2001.24371  0.312
2001 Tseng CTK, Miskovsky E, Houghton M, Klimpel GR. Characterization of liver T-cell receptor γδ+ T cells obtained from individuals chronically infected with hepatitis C virus (HCV): Evidence for these T cells playing a role in the liver pathology associated with HCV infections Hepatology. 33: 1312-1320. PMID 11343261 DOI: 10.1053/Jhep.2001.24269  0.375
2001 Wack A, Soldaini E, Tseng CTK, Nuti S, Klimpel GR, Abrignani S. Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co-stimulatory signal for human T cells European Journal of Immunology. 31: 166-175. PMID 11169450 DOI: 10.1002/1521-4141(200101)31:1<166::Aid-Immu166>3.0.Co;2-L  0.344
2001 Tseng CTK, Miskovsky E, Klimpel GR. Crosslinking CD81 results in activation of TCRγδ T cells Cellular Immunology. 207: 19-27. PMID 11161449 DOI: 10.1006/Cimm.2000.1744  0.303
2000 Wang T, Alam R, Langley KE, Klimpel GR. Stem cell factor and IL-2 act synergistically in inducing intraepithelial lymphocyte proliferation and cytokine production: upregulation of the IL-2 receptor gamma-chain and signaling via JAK-3. Cellular Immunology. 205: 62-71. PMID 11078608 DOI: 10.1006/Cimm.2000.1707  0.371
2000 Wang T, Langley KE, Gourley WK, Klimpel GR. Stem cell factor (SCF) can regulate the activation and expansion of murine intraepithelial lymphocytes. Cytokine. 12: 272-80. PMID 10704255 DOI: 10.1006/Cyto.1999.0551  0.397
2000 Soler-Rodriguez AM, Zhang H, Lichenstein HS, Qureshi N, Niesel DW, Crowe SE, Peterson JW, Klimpel GR. Neutrophil activation by bacterial lipoprotein versus lipopolysaccharide: differential requirements for serum and CD14. Journal of Immunology (Baltimore, Md. : 1950). 164: 2674-83. PMID 10679108 DOI: 10.4049/Jimmunol.164.5.2674  0.302
2000 Denning TL, Campbell NA, Song F, Garofalo RP, Klimpel GR, Reyes VE, Ernst PB. Expression of IL-10 receptors on epithelial cells from the murine small and large intestine International Immunology. 12: 133-139. PMID 10653848 DOI: 10.1093/Intimm/12.2.133  0.371
1999 Aliprantis AO, Yang RB, Mark MR, Suggett S, Devaux B, Radolf JD, Klimpel GR, Godowski P, Zychlinsky A. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science (New York, N.Y.). 285: 736-9. PMID 10426996 DOI: 10.1126/Science.285.5428.736  0.379
1999 Ernst PB, Song F, Klimpel GR, Haeberle H, Bamford KB, Crowe SE, Ye G, Reyes VE. Regulation of the mucosal immune response. The American Journal of Tropical Medicine and Hygiene. 60: 2-9. PMID 10344671 DOI: 10.4269/Ajtmh.1999.60.2  0.322
1998 Zhang H, Niesel DW, Peterson JW, Klimpel GR. Lipoprotein release by bacteria: Potential factor in bacterial pathogenesis Infection and Immunity. 66: 5196-5201. PMID 9784522 DOI: 10.1128/Iai.66.11.5196-5201.1998  0.312
1998 Wang L, Klimpel GR, Planas JM, Li H, Cloyd MW. Apoptotic killing of CD4+ T lymphocytes in HIV-1-infected PHA-stimulated PBL cultures is mediated by CD8+ LAK cells. Virology. 241: 169-80. PMID 9499792 DOI: 10.1006/Viro.1997.8979  0.361
1996 Peterson JW, Dickey WD, Saini SS, Gourley W, Klimpel GR, Chopra AK. Phospholipase A2 activating protein and idiopathic inflammatory bowel disease Gut. 39: 698-704. PMID 9014769 DOI: 10.1136/Gut.39.5.698  0.325
1996 Zhang H, Kaur I, Niesel DW, Seetharamaiah GS, Peterson JW, Justement LB, Prabhakar BS, Klimpel GR. Yersinia enterocolitica envelope proteins that are crossreactive with the thyrotropin receptor (TSHR) also have B-cell mitogenic activity Journal of Autoimmunity. 9: 509-516. PMID 8864826 DOI: 10.1006/Jaut.1996.0068  0.417
1996 Sower LE, Klimpel GR, Hanna W, Froelich CJ. Extracellular activities of human granzymes: I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines Cellular Immunology. 171: 159-163. PMID 8754861 DOI: 10.1006/Cimm.1996.0187  0.398
1996 Klimpel GR, Langley KE, Wypych J, Abrams JS, Chopra AK, Niesel DW. A role for stem cell factor (SCF): c-kit interaction(s) in the intestinal tract response to Salmonella typhimurium infection. The Journal of Experimental Medicine. 184: 271-6. PMID 8691142 DOI: 10.1084/Jem.184.1.271  0.377
1996 Peterson JW, Saini SS, Dickey WD, Klimpel GR, Bomalaski JS, Clark MA, Xu XJ, Chopra AK. Cholera toxin induces synthesis of phospholipase A2-activating protein Infection and Immunity. 64: 2137-2143. PMID 8675318 DOI: 10.1128/Iai.64.6.2137-2143.1996  0.305
1995 Klimpel GR, Asuncion M, Haithcoat J, Niesel DW. Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract Infection and Immunity. 63: 1134-1137. PMID 7868239 DOI: 10.1128/Iai.63.3.1134-1137.1995  0.359
1995 Guo Y, Ziegler HK, Safley SA, Niesel DW, Vaidya S, Klimpel GR. Human T-cell recognition of Listeria monocytogenes: Recognition of listeriolysin O by TcRαβ+ and TcRγδ+ T cells Infection and Immunity. 63: 2288-2294. PMID 7768611 DOI: 10.1128/Iai.63.6.2288-2294.1995  0.388
1995 Klimpel GR, Chopra AK, Langley KE, Wypych J, Annable CA, Kaiserlian D, Ernst PB, Peterson JW. A role for stem cell factor and c-kit in the murine intestinal tract secretory response to cholera toxin. The Journal of Experimental Medicine. 182: 1931-42. PMID 7500039 DOI: 10.1084/Jem.182.6.1931  0.326
1994 Brooks EG, Klimpel GR, Vaidya SE, Keeney SE, Raimer S, Goldman AS, Schmalstieg FC. Thymic hypoplasia and T-cell deficiency in ectodermal dysplasia: case report and review of the literature. Clinical Immunology and Immunopathology. 71: 44-52. PMID 8137558 DOI: 10.1006/Clin.1994.1050  0.386
1993 Brooks EG, Wirt DP, Klimpel GR, Vaidya S, Goldblum RM. In Vivo and in Vitro Suppression of T-Cell Receptor α/β CD4-CD8- T Lymphocytes by Cyclosporine A Clinical Immunology and Immunopathology. 67: 224-231. PMID 8500270 DOI: 10.1006/Clin.1993.1069  0.374
1993 Ramarathinam L, Niesel DW, Klimpel GR. Salmonella typhimurium induces IFN-γ production in murine splenocytes: Role of natural killer cells and macrophages Journal of Immunology. 150: 3973-3981. PMID 8473744  0.358
1993 Ramarathinam L, Niesel DW, Klimpel GR. Ity influences the production of IFN-γ by murine splenocytes stimulated in vitro with Salmonella typhimurium Journal of Immunology. 150: 3965-3972. PMID 8473743  0.319
1993 Naldini A, Carney DH, Bocci V, Klimpel KD, Asuncion M, Soares LE, Klimpel GR. Thrombin enhances T cell proliferative responses and cytokine production. Cellular Immunology. 147: 367-77. PMID 8453678 DOI: 10.1006/Cimm.1993.1076  0.443
1993 Arnold JW, Klimpel GR, Niesel DW. Tumor Necrosis Factor (TNFα) Regulates Intestinal Mucus Production during Salmonellosis Cellular Immunology. 151: 336-344. PMID 8402940 DOI: 10.1006/Cimm.1993.1243  0.38
1993 Luo G, Niesel DW, Shaban RA, Grimm EA, Klimpel GR. Tumor necrosis factor alpha binding to bacteria: Evidence for a high- affinity receptor and alteration of bacterial virulence properties Infection and Immunity. 61: 830-835. PMID 8381771 DOI: 10.1128/Iai.61.3.830-835.1993  0.332
1993 Arnold JW, Niesel DW, Annable CR, Hess CB, Asuncion M, Cho YJ, Peterson JW, Klimpel GR. Tumor necrosis factor-α mediates the early pathology in Salmonella infection of the gastrointestinal tract Microbial Pathogenesis. 14: 217-227. PMID 8321123 DOI: 10.1006/Mpat.1993.1021  0.36
1992 Guo Y, Niesel DW, Ziegler HK, Klimpel GR. Listeria monocytogenes activation of human peripheral blood lymphocytes: Induction of non-major histocompatibility complex-restricted cytotoxic activity and cytokine production Infection and Immunity. 60: 1813-1819. PMID 1373400 DOI: 10.1128/Iai.60.5.1813-1819.1992  0.464
1991 Ramarathinam L, Shaban RA, Niesel DW, Klimpel GR. Interferon gamma (IFN-γ) production by gut-associated lymphoid tissue and spleen following oral Salmonella typhimurium challenge Microbial Pathogenesis. 11: 347-356. PMID 1816488 DOI: 10.1016/0882-4010(91)90020-B  0.396
1991 Baron S, Tyring SK, Fleischmann WR, Coppenhaver DH, Niesel DW, Klimpel GR, Stanton GJ, Hughes TK. The interferons. Mechanisms of action and clinical applications. Jama. 266: 1375-83. PMID 1715409 DOI: 10.1001/Jama.266.10.1375  0.365
1990 Klimpel GR, Infante AJ, Patterson J, Hess CB, Asuncion M. Virus-induced interferon α β (IFN- α β) production by T cells and by Th1 and Th2 helper T cell clones: A study of the immunoregulatory actions of IFN-γ versus IFN- α β on functions of different T cell populations Cellular Immunology. 128: 603-618. PMID 2162739 DOI: 10.1016/0008-8749(90)90052-S  0.302
1990 Hess CB, Niesel DW, Holmgren J, Jonson G, Klimpel GR. Interferon production by Shigella flexneri-infected fibroblasts depends upon intracellular bacterial metabolism Infection and Immunity. 58: 399-405. PMID 1688826 DOI: 10.1128/Iai.58.2.399-405.1990  0.377
1989 Wirt DP, Brooks EG, Vaidya S, Klimpel GR, Waldmann TA, Goldblum RM. Novel T-lymphocyte population in combined immunodeficiency with features of graft-versus-host disease New England Journal of Medicine. 321: 370-374. PMID 2787478 DOI: 10.1056/Nejm198908103210606  0.383
1989 Hess CB, Niesel DW, Klimpel GR. The induction of interferon production in fibroblasts by invasive bacteria: a comparison of Salmonella and Shigella species Microbial Pathogenesis. 7: 111-120. PMID 2687612 DOI: 10.1016/0882-4010(89)90030-2  0.448
1988 Cleveland MG, Annable CR, Klimpel GR. In vivo and in vitro production of IFN-β and IFN-γ during graft host disease Journal of Immunology. 141: 3349-3356. PMID 3141498  0.346
1988 Klimpel GR, Herndon DH, Stein MD. Peripheral blood lymphocytes from thermal injury patients are defective in their ability to generate lymphokine-activated killer (LAK) cell activity Journal of Clinical Immunology. 8: 14-22. PMID 2966807 DOI: 10.1007/Bf00915152  0.365
1988 Cleveland MG, Ramirez RB, Klimpel GR. IFN-β production by macrophages obtained from mice undergoing graft vs host disease Journal of Immunology. 141: 3823-3827. PMID 2846694  0.358
1988 Klimpel GR, Niesel DW, Asuncion M, Klimpel KD. Natural killer cell activation and interferon production by peripheral blood lymphocytes after exposure to bacteria Infection and Immunity. 56: 1436-1441. PMID 2453465 DOI: 10.1128/Iai.56.6.1436-1441.1988  0.469
1987 Reyes VE, Klimpel GR. Interferon α/β synthesis during acute graft-versus-host disease Transplantation. 43: 412-416. PMID 3547798 DOI: 10.1097/00007890-198703000-00018  0.389
1987 Hess CB, Niesel DW, Cho YJ, Klimpel GR. Bacterial invasion of fibroblasts induces interferon production Journal of Immunology. 138: 3949-3953. PMID 3295042  0.333
1987 Cleveland MG, Lane RG, Klimpel GR. Enhanced interferon- α β (IFN- α β) and defective IFN-γ production in chronic graft versus host disease: A potential mechanism for immunosuppression Cellular Immunology. 110: 120-130. PMID 3119228 DOI: 10.1016/0008-8749(87)90106-7  0.4
1987 Sarzotti M, Baron S, Klimpel GR. EL‐4 metastases in spleen and bone marrow suppress the nk activity generated in these organs International Journal of Cancer. 39: 118-125. PMID 2947865 DOI: 10.1002/Ijc.2910390121  0.37
1986 Klimpel GR, Niesel DW, Klimpel KD. Natural cytotoxic effector cell activity against Shigella flexneri-infected HeLa cells Journal of Immunology. 136: 1081-1086. PMID 3510252  0.365
1986 Klimpel GR, Herndon DN, Fons M, Albrecht T, Asuncion MT, Chin R, Stein MD. Defective NK cell activity following thermal injury Clinical and Experimental Immunology. 66: 384-392. PMID 3493101  0.324
1986 Reyes VE, Ballas ZK, Singh H, Klimpel GR. Interleukin 2 induces interferon α β production in mouse bone marrow cells Cellular Immunology. 102: 374-385. PMID 3100059 DOI: 10.1016/0008-8749(86)90431-4  0.433
1986 Niesel DW, Hess CB, Cho YJ, Klimpel KD, Klimpel GR. Natural and recombinant interferons inhibit epithelial cell invasion by Shigella spp Infection and Immunity. 52: 828-833. PMID 3086234 DOI: 10.1128/Iai.52.3.828-833.1986  0.423
1986 Carr DJJ, Klimpel GR. Enhancement of the generation of cytotoxic T cells by endogenous opiates Journal of Neuroimmunology. 12: 75-87. PMID 2940263 DOI: 10.1016/0165-5728(86)90099-8  0.316
1985 Reyes VE, Klimpel KD, Klimpel GR. T cell regulation of interferon α/β (IFN-α/β) production by alloantigen-stimulated bone marrow cells Journal of Immunology. 134: 3137-3141. PMID 2858508  0.303
1985 Klimpel GR, Sarzotti M, Reyes VE, Klimpel KD. Characterization of cytotoxic cells generated from in vitro cultures of murine bone marrow cells Cellular Immunology. 92: 1-13. PMID 2416478 DOI: 10.1016/0008-8749(85)90059-0  0.395
1984 Tyring SK, Klimpel G, Brysk M, Gupta V, Stanton GJ, Fleischmann WR, Baron S. Eradication of cultured human melanoma cells by immune interferon and leukocytes. Journal of the National Cancer Institute. 73: 1067-73. PMID 6436563 DOI: 10.1093/Jnci/73.5.1067  0.35
1984 Stein MD, Gamble DN, Klimpel KD, Herndon DN, Klimpel GR. Natural killer cell defects resulting from thermal injury Cellular Immunology. 86: 551-556. PMID 6428755 DOI: 10.1016/0008-8749(84)90412-X  0.354
1984 Lett-Brown MA, Kalman V, Klimpel GR. Histamine production by alloantigen-activated mouse bone marrow cells Cellular Immunology. 87: 53-64. PMID 6204778 DOI: 10.1016/0008-8749(84)90129-1  0.346
1983 Kalman VK, Klimpel GR. Cyclosporin A inhibits the production of gamma interferon (IFNγ), but does not inhibit production of virus-induced IFNα/β Cellular Immunology. 78: 122-129. PMID 6406074 DOI: 10.1016/0008-8749(83)90265-4  0.402
1982 Tyring S, Klimpel GR, Fleischmann WR, Baron S. Direct cytolysis by partially-purified preparations of immune interferon International Journal of Cancer. 30: 69-64. PMID 6180990 DOI: 10.1002/Ijc.2910300111  0.414
1982 Klimpel GR, Fleischmann WR, Baron S, Klimpel KD. Mouse bone marrow cells produce a different interferon (IFN) than do spleen cells in response to alloantigens Journal of Immunology. 129: 946-949. PMID 6180005  0.325
1980 Klimpel GR. Soluble factor(s) from LPS-activated macrophages induce cytotoxic T cell differentiation from alloantigen-primed spleen cells Journal of Immunology. 125: 1243-1249. PMID 6967896  0.305
1979 Klimpel GR. Soluble factors from BCG-induced suppressor cells inhibit in vitro PFC responses but not cytotoxic responses Cellular Immunology. 47: 218-226. PMID 159779 DOI: 10.1016/0008-8749(79)90331-9  0.322
1979 Klimpel GR, Okada M, Henney CS. Inhibition of in vitro cytotoxic responses by BCG-induced macrophage-like suppressor cells. II. Suppression occurs at the level of a 'helper' T cell Journal of Immunology. 123: 350-357. PMID 156233  0.364
1979 Okada M, Klimpel GR, Kuppers RC, Henney CS. The differentiation of cytotoxic T cells in vitro. I. Amplifying factor(s) in the primary response is Lyt 1+ cell dependent Journal of Immunology. 122: 2527-2533. PMID 156228  0.32
1978 Klimpel GR, Henney CS. A comparison of the effects of T and macrophage-like suppressor cells on memory cell differentiation in vitro Journal of Immunology. 121: 749-754. PMID 355552  0.313
1978 Klimpel GR, Henney CS. BCG-induced suppressor cells. I. Demonstration of a macrophage-like suppressor cell that inhibits cytotoxic T cell generation in vitro Journal of Immunology. 120: 563-569. PMID 304460  0.353
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