185 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, et al. USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism. Proceedings of the National Academy of Sciences of the United States of America. 120: e2315163120. PMID 38055744 DOI: 10.1073/pnas.2315163120  0.394
2021 Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, ... ... Neefjes J, et al. The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses. Immunity. 54: 387. PMID 33567263 DOI: 10.1016/j.immuni.2021.01.016  0.478
2020 Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, ... ... Neefjes J, et al. The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses. Immunity. PMID 33271119 DOI: 10.1016/j.immuni.2020.11.003  0.522
2020 Margiotta A, Frei DM, Sendstad IH, Janssen L, Neefjes J, Bakke O. Invariant chain regulates endosomal fusion and maturation through an interaction with the SNARE Vti1b. Journal of Cell Science. 133. PMID 32907852 DOI: 10.1242/Jcs.244624  0.418
2020 Qiao X, van der Zanden SY, Wander DPA, Borràs DM, Song JY, Li X, van Duikeren S, van Gils N, Rutten A, van Herwaarden T, van Tellingen O, Giacomelli E, Bellin M, Orlova V, Tertoolen LGJ, ... ... Neefjes J, et al. Uncoupling DNA damage from chromatin damage to detoxify doxorubicin. Proceedings of the National Academy of Sciences of the United States of America. PMID 32554494 DOI: 10.1073/Pnas.1922072117  0.483
2020 van der Zanden SY, Luimstra JJ, Neefjes J, Borst J, Ovaa H. Opportunities for Small Molecules in Cancer Immunotherapy. Trends in Immunology. PMID 32381382 DOI: 10.1016/J.It.2020.04.004  0.332
2020 Neefjes J, Overkleeft H, Ploegh H, Schulman B. Huib Ovaa (1973–2020) Chemistry & Biology. 27: 645-646. DOI: 10.1016/J.Chembiol.2020.06.003  0.372
2019 Mishto M, Mansurkhodzhaev A, Ying G, Bitra A, Cordfunke RA, Henze S, Paul D, Sidney J, Urlaub H, Neefjes J, Sette A, Zajonc DM, Liepe J. An Pipeline Identifying an HLA-A02:01 KRAS G12V Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Frontiers in Immunology. 10: 2572. PMID 31803176 DOI: 10.3389/Fimmu.2019.02572  0.384
2019 Luimstra JJ, Franken KLMC, Garstka MA, Drijfhout JW, Neefjes J, Ovaa H. Production and Thermal Exchange of Conditional Peptide-MHC I Multimers. Current Protocols in Immunology. 126. PMID 31483102 DOI: 10.1002/Cpim.85  0.405
2019 Döring M, Blees H, Koller N, Tischer-Zimmermann S, Müsken M, Henrich F, Becker J, Grabski E, Wang J, Janssen H, Zuschratter W, Neefjes J, Klawonn F, Eiz-Vesper B, Tampé R, et al. Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation. Blood Advances. 3: 839-850. PMID 30867143 DOI: 10.1182/Bloodadvances.2018027268  0.371
2019 Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, ... Neefjes J, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nature Medicine. 25: 612-619. PMID 30833751 DOI: 10.1038/S41591-019-0356-Z  0.557
2019 Perrin P, Jongsma ML, Neefjes J, Berlin I. The labyrinth unfolds: architectural rearrangements of the endolysosomal system in antigen-presenting cells. Current Opinion in Immunology. 58: 1-8. PMID 30738283 DOI: 10.1016/J.Coi.2018.12.004  0.446
2019 Grimm SH, Gagestein B, Keijzer JF, Liu N, Wijdeven RH, Lenselink EB, Tuin AW, van den Nieuwendijk AMCH, van Westen GJP, van Boeckel CAA, Overkleeft HS, Neefjes J, van der Stelt M. Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors. Bioorganic & Medicinal Chemistry. PMID 30661740 DOI: 10.1016/J.Bmc.2019.01.006  0.47
2019 Aslam MA, Alemdehy MF, Pritchard CEJ, Song JY, Muhaimin FI, Wijdeven RH, Huijbers IJ, Neefjes J, Jacobs H. Towards an understanding of C9orf82 protein/CAAP1 function. Plos One. 14: e0210526. PMID 30629682 DOI: 10.1371/Journal.Pone.0210526  0.335
2018 Wijdeven RH, van Luijn MM, Wierenga-Wolf AF, Akkermans JJ, van den Elsen PJ, Hintzen RQ, Neefjes J. Chemical and genetic control of IFNγ-induced MHCII expression. Embo Reports. 19. PMID 30021835 DOI: 10.15252/Embr.201745553  0.337
2018 Cabukusta B, Neefjes J. Mechanisms of lysosomal positioning and movement. Traffic (Copenhagen, Denmark). 19: 761-769. PMID 29900632 DOI: 10.1111/Tra.12587  0.329
2018 Luimstra JJ, Garstka MA, Roex MCJ, Redeker A, Janssen GMC, van Veelen PA, Arens R, Falkenburg JHF, Neefjes J, Ovaa H. A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells. The Journal of Experimental Medicine. PMID 29666167 DOI: 10.1084/Jem.20180156  0.432
2018 Lamers M, Berlin I, Neefjes J. Antigen Presentation: Visualizing the MHC Class I Peptide-Loading Bottleneck. Current Biology : Cb. 28: R83-R86. PMID 29374452 DOI: 10.1016/J.Cub.2017.11.059  0.427
2018 Verweij FJ, Bebelman MP, Jimenez CR, Garcia-Vallejo JJ, Janssen H, Neefjes J, Knol JC, de Goeij-de Haas R, Piersma SR, Baglio SR, Verhage M, Middeldorp JM, Zomer A, van Rheenen J, Coppolino MG, et al. Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling. The Journal of Cell Biology. PMID 29339438 DOI: 10.1083/Jcb.201703206  0.306
2017 Dohmen AJC, Qiao X, Duursma A, Wijdeven RH, Lieftink C, Hageman F, Morris B, Halonen P, Vens C, van den Brekel MWM, Ovaa H, Neefjes J, Zuur CL. Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity. Oncotarget. 8: 73925-73937. PMID 29088757 DOI: 10.18632/Oncotarget.18034  0.304
2016 Rock KL, Reits E, Neefjes J. Present Yourself! By MHC Class I and MHC Class II Molecules. Trends in Immunology. 37: 724-737. PMID 27614798 DOI: 10.1016/J.It.2016.08.010  0.449
2016 Jongsma ML, Berlin I, Wijdeven RH, Janssen L, Janssen GM, Garstka MA, Janssen H, Mensink M, van Veelen PA, Spaapen RM, Neefjes J. An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport. Cell. 166: 152-66. PMID 27368102 DOI: 10.1016/J.Cell.2016.05.078  0.301
2016 Stolze SC, Liu N, Wijdeven RH, Tuin AW, van den Nieuwendijk AM, Florea BI, van der Stelt M, van der Marel GA, Neefjes JJ, Overkleeft HS. Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes. Molecular Biosystems. PMID 27138522 DOI: 10.1039/c6mb00257a  0.383
2016 Unanue ER, Turk V, Neefjes J. Variations in MHC Class II Antigen Processing and Presentation in Health and Disease. Annual Review of Immunology. PMID 26907214 DOI: 10.1146/Annurev-Immunol-041015-055420  0.415
2015 van der Kant R, Jonker CT, Wijdeven RH, Bakker J, Janssen L, Klumperman J, Neefjes J. Characterization of the mammalian CORVET and HOPS complexes and their modular restructuring for endosome specificity. The Journal of Biological Chemistry. PMID 26463206 DOI: 10.1074/Jbc.M115.688440  0.316
2015 Berkers CR, de Jong A, Schuurman KG, Linnemann C, Meiring HD, Janssen L, Neefjes JJ, Schumacher TN, Rodenko B, Ovaa H. Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules. Journal of Immunology (Baltimore, Md. : 1950). PMID 26401003 DOI: 10.4049/Jimmunol.1402455  0.528
2015 van Luijn MM, Kreft KL, Jongsma ML, Mes SW, Wierenga-Wolf AF, van Meurs M, Melief MJ, der Kant Rv, Janssen L, Janssen H, Tan R, Priatel JJ, Neefjes J, Laman JD, Hintzen RQ. Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis Brain : a Journal of Neurology. 138: 1531-1547. PMID 25823473 DOI: 10.1093/Brain/Awv080  0.419
2015 Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, Hoppes R, Stadnik M, Janssen L, Ovaa H, van Veelen PA, Perrakis A, Neefjes J. The first step of peptide selection in antigen presentation by MHC class I molecules. Proceedings of the National Academy of Sciences of the United States of America. 112: 1505-10. PMID 25605945 DOI: 10.1073/Pnas.1416543112  0.394
2015 De Wit J, Jorritsma T, Makuch M, Remmerswaal EBM, Klaasse Bos H, Souwer Y, Neefjes J, Ten Berge IJM, Van Ham SM. Human B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures Journal of Allergy and Clinical Immunology. 135: 1053-1060. PMID 25258142 DOI: 10.1016/J.Jaci.2014.08.012  0.309
2015 van Deventer S, Menendez-Benito V, van Leeuwen F, Neefjes J. N-terminal acetylation and replicative age affect proteasome localization and cell fitness during aging Journal of Cell Science. 128: 109-117. DOI: 10.1242/Jcs.157354  0.304
2015 Neefjes J. Expanding the peptidome for immunotherapy Blood. 126: 1154-1156. DOI: 10.1182/Blood-2015-07-657130  0.32
2014 Verbrugge I, Gasparini A, Haynes NM, Hagekyriakou J, Galli M, Stewart TJ, Abrams SI, Yagita H, Verheij M, Johnstone RW, Borst J, Neefjes J. The curative outcome of radioimmunotherapy in a mouse breast cancer model relies on mTOR signaling. Radiation Research. 182: 219-29. PMID 24960417 DOI: 10.1667/Rr13511.1  0.338
2014 van Kasteren SI, Overkleeft H, Ovaa H, Neefjes J. Chemical biology of antigen presentation by MHC molecules Current Opinion in Immunology. 26: 21-31. PMID 24556397 DOI: 10.1016/J.Coi.2013.10.005  0.594
2014 Spaapen R, Blomen V, van Veelen P, Jongsma M, Janssen L, Janssen G, Raaben M, Brummelkamp T, Neefjes J. Identification of potential immunotherapeutic targets in antigen presentation and costimulation networks Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P126  0.416
2013 Neefjes J, Ovaa H. A peptide's perspective on antigen presentation to the immune system Nature Chemical Biology. 9: 769-775. PMID 24231618 DOI: 10.1038/Nchembio.1391  0.369
2013 Kuijl C, Pilli M, Alahari SK, Janssen H, Khoo PS, Ervin KE, Calero M, Jonnalagadda S, Scheller RH, Neefjes J, Junutula JR. Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria. The Embo Journal. 32: 713-27. PMID 23386062 DOI: 10.1038/Emboj.2013.10  0.303
2013 Paul P, Neefjes J. Studying MHC class II transport in dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 960: 489-507. PMID 23329509 DOI: 10.1007/978-1-62703-218-6_36  0.473
2013 Jongsma MLM, Neefjes J. Assaying peptide translocation by the peptide transporter TAP Methods in Molecular Biology. 960: 53-65. PMID 23329478 DOI: 10.1007/978-1-62703-218-6_5  0.412
2013 Menendez-Benito V, Van Deventer SJ, Jimenez-Garcia V, Roy-Luzarraga M, Van Leeuwen F, Neefjes J. Spatiotemporal analysis of organelle and macromolecular complex inheritance Proceedings of the National Academy of Sciences of the United States of America. 110: 175-180. PMID 23248297 DOI: 10.1073/Pnas.1207424110  0.302
2013 Garstka MA, Neefjes J. How to target MHC class II into the MIIC compartment Molecular Immunology. 55: 162-165. PMID 23200228 DOI: 10.1016/J.Molimm.2012.10.022  0.448
2013 Wijdeven RH, Bakker JM, Paul P, Neefjes J. Exploring genome-wide datasets of MHC class II antigen presentation. Molecular Immunology. 55: 172-4. PMID 23137594 DOI: 10.1016/J.Molimm.2012.10.014  0.389
2012 Souwer Y, Griekspoor A, de Wit J, Martinoli C, Zagato E, Janssen H, Jorritsma T, Bar-Ephraïm YE, Rescigno M, Neefjes J, van Ham SM. Selective Infection of Antigen-Specific B Lymphocytes by Salmonella Mediates Bacterial Survival and Systemic Spreading of Infection Plos One. 7. PMID 23209805 DOI: 10.1371/Journal.Pone.0050667  0.301
2012 Neefjes J, Sadaka C. Into the intracellular logistics of cross-presentation. Frontiers in Immunology. 3: 31. PMID 22566915 DOI: 10.3389/fimmu.2012.00031  0.333
2012 Majera D, Kristan KC, Neefjes J, Turk D, Miheli? M. Expression, purification and assembly of soluble multimeric MHC class II-invariant chain complexes Febs Letters. 586: 1318-1324. PMID 22465664 DOI: 10.1016/J.Febslet.2012.03.038  0.378
2012 Houtman R, De Leeuw R, Rondaij M, Melchers D, Verwoerd D, Ruijtenbeek R, Martens JWM, Neefjes J, Michalides R. Serine-305 phosphorylation modulates estrogen receptor alpha binding to a coregulator peptide array, with potential application in predicting responses to tamoxifen Molecular Cancer Therapeutics. 11: 805-816. PMID 22319200 DOI: 10.1158/1535-7163.Mct-11-0855  0.31
2012 Hoorn Tv, Paul P, Janssen L, Janssen H, Neefjes J. Dynamics within tetraspanin pairs affect MHC class II expression. Journal of Cell Science. 125: 328-39. PMID 22302999 DOI: 10.1242/Jcs.088047  0.314
2012 Neefjes J, Sadaka C. Into the intracellular logistics of cross-presentation Frontiers in Immunology. 3. DOI: 10.3389/Fimmu.2012.00031  0.442
2012 Spaapen R, Blomen V, Raaben M, Brummelkamp T, Neefjes J. Haploid genetic screening to identify novel regulators of MHC class I antigen presentation Molecular Immunology. 51: 31. DOI: 10.1016/J.Molimm.2012.02.085  0.354
2012 Paul P, van den Hoorn T, Jongsma M, Janssen L, Cresswell P, van Ham M, ten Brinke A, Kuijl C, Neefjes J. A multi-dimensional RNAi screen reveals pathways controlling MHC Class II antigen presentation Molecular Immunology. 51: 27. DOI: 10.1016/J.Molimm.2012.02.073  0.38
2012 Garstka G, Berlin I, Jongsma M, van der Pijl L, Neefjes J. Tollip plays a role in the biogenesis of MHC class II compartment Molecular Immunology. 51: 15. DOI: 10.1016/J.Molimm.2012.02.036  0.371
2012 Berlin I, Wijdeven R, Garstka M, Neefjes J. Deubiquitinating enzymes in control of MHC class-II transport Molecular Immunology. 51: 8-9. DOI: 10.1016/J.Molimm.2012.02.017  0.357
2012 Bakker J, Neefjes J. Identifying MHC class II peptide loading control mechanisms Molecular Immunology. 51: 7. DOI: 10.1016/J.Molimm.2012.02.013  0.391
2011 Neefjes J, Jongsma ML, Paul P, Bakke O. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nature Reviews. Immunology. 11: 823-36. PMID 22076556 DOI: 10.1038/Nri3084  0.428
2011 Paul P, van den Hoorn T, Jongsma ML, Bakker MJ, Hengeveld R, Janssen L, Cresswell P, Egan DA, van Ham M, Ten Brinke A, Ovaa H, Beijersbergen RL, Kuijl C, Neefjes J. A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell. 145: 268-83. PMID 21458045 DOI: 10.1016/J.Cell.2011.03.023  0.431
2011 Kessler JH, Khan S, Seifert U, Le Gall S, Chow KM, Paschen A, Bres-Vloemans SA, De Ru A, Van Montfoort N, Franken KLMC, Benckhuijsen WE, Brooks JM, Van Hall T, Ray K, Mulder A, ... ... Neefjes J, et al. Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes Nature Immunology. 12: 45-53. PMID 21151101 DOI: 10.1038/Ni.1974  0.59
2011 van den Hoorn T, Paul P, Jongsma ML, Neefjes J. Routes to manipulate MHC class II antigen presentation. Current Opinion in Immunology. 23: 88-95. PMID 21112200 DOI: 10.1016/J.Coi.2010.11.002  0.419
2010 Zwart W, Peperzak V, de Vries E, Keller AM, van der Horst G, Veraar EA, Geumann U, Janssen H, Janssen L, Naik SH, Neefjes J, Borst J. The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells. Journal of Cell Science. 123: 3817-27. PMID 20971706 DOI: 10.1242/Jcs.068510  0.39
2010 de Wit J, Souwer Y, Jorritsma T, Bos HK, Brinke tA, Neefjes J, Marieke van Ham S. Antigen-specific B cells reactivate an effective cytotoxic T Cell response against phagocytosed Salmonella through cross-presentation Plos One. 5. PMID 20885961 DOI: 10.1371/Journal.Pone.0013016  0.37
2010 Broxterman HJG, van der Marel GA, van Boom JH, Neefjes JJ, Ploegh HL. Synthesis of the antibiotic 1,5-dideoxy-1,5-imino-D-glucitol; concomitant formation of the D-mannitol analogue Recueil Des Travaux Chimiques Des Pays-Bas. 106: 571-576. DOI: 10.1002/recl.19871061105  0.301
2009 Pang B, Neijssen J, Qiao X, Janssen L, Janssen H, Lippuner C, Neefjes J. Direct antigen presentation and gap junction mediated cross-presentation during apoptosis Journal of Immunology. 183: 1083-1090. PMID 19553546 DOI: 10.4049/Jimmunol.0900861  0.368
2009 Souwer Y, Griekspoor A, Jorritsma T, De Wit J, Janssen H, Neefjes J, Van Ham SM. B cell receptor-mediated internalization of Salmonella: A novel pathway for autonomous B cell activation and antibody production Journal of Immunology. 182: 7473-7481. PMID 19494270 DOI: 10.4049/Jimmunol.0802831  0.341
2008 Kuijl C, Tuin AW, Overkleeft H, Neefjes J. Reciprocal chemical genetics for swift lead and target identification Molecular Biosystems. 4: 1001-1008. PMID 19082139 DOI: 10.1039/B803265N  0.441
2008 van den Hoorn T, Neefjes J. Activated pDCs: Open to new antigen-presentation possibilities Nature Immunology. 9: 1208-1210. PMID 18936779 DOI: 10.1038/Ni1108-1208  0.445
2008 Koppers-Lalic D, Verweij MC, Lipi?ska AD, Wang Y, Quinten E, Reits EA, Koch J, Loch S, Marcondes Rezende M, Daus F, Bie?kowska-Szewczyk K, Osterrieder N, Mettenleiter TC, Heemskerk MH, Tampé R, ... Neefjes JJ, et al. Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP. Plos Pathogens. 4: e1000080. PMID 18516302 DOI: 10.1371/Journal.Ppat.1000080  0.345
2008 Rocha N, Neefjes J. MHC class II molecules on the move for successful antigen presentation Embo Journal. 27: 1-5. PMID 18046453 DOI: 10.1038/Sj.Emboj.7601945  0.419
2007 Kuijl C, Savage NDL, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, Van Den Nieuwendijk R, Van Den Eeden SJF, Geluk A, Poot A, Van Der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff THM, ... Neefjes J, et al. Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1 Nature. 450: 725-730. PMID 18046412 DOI: 10.1038/Nature06345  0.463
2007 Keller AM, Groothuis TA, Veraar EA, Marsman M, Maillette de Buy Wenniger L, Janssen H, Neefjes J, Borst J. Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 104: 5989-94. PMID 17389361 DOI: 10.1073/Pnas.0700946104  0.359
2007 Menéndez-Benito V, Neefjes J. Autophagy in MHC Class II Presentation: Sampling from Within Immunity. 26: 1-3. PMID 17241953 DOI: 10.1016/J.Immuni.2007.01.005  0.405
2006 Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, et al. A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chemistry & Biology. 13: 1217-26. PMID 17114003 DOI: 10.1016/J.Chembiol.2006.09.013  0.419
2006 Elliott T, Neefjes J. The Complex Route to MHC Class I-Peptide Complexes Cell. 127: 249-251. PMID 17055423 DOI: 10.1016/J.Cell.2006.10.001  0.411
2006 Qian SB, Reits E, Neefjes J, Deslich JM, Bennink JR, Yewdell JW. Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products Journal of Immunology. 177: 227-233. PMID 16785518 DOI: 10.4049/Jimmunol.177.1.227  0.402
2006 Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, Wansley EK, Camphausen K, Luiten RM, de Ru AH, Neijssen J, Griekspoor A, Mesman E, Verreck FA, Spits H, Schlom J, ... ... Neefjes JJ, et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. The Journal of Experimental Medicine. 203: 1259-71. PMID 16636135 DOI: 10.1084/jem.20052494  0.347
2006 Groothuis T, Neefjes J. The ins and outs of intracellular peptides and antigen presentation by MHC class I molecules Current Topics in Microbiology and Immunology. 300: 127-148. PMID 16573239 DOI: 10.1007/3-540-28007-3_6  0.456
2005 Groothuis TAM, Neefjes J. The many roads to cross-presentation Journal of Experimental Medicine. 202: 1313-1318. PMID 16287713 DOI: 10.1084/Jem.20051379  0.4
2005 Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 175: 6605-14. PMID 16272315 DOI: 10.4049/Jimmunol.175.10.6605  0.349
2005 Groothuis TA, Griekspoor AC, Neijssen JJ, Herberts CA, Neefjes JJ. MHC class I alleles and their exploration of the antigen-processing machinery. Immunological Reviews. 207: 60-76. PMID 16181327 DOI: 10.1111/j.0105-2896.2005.00305.x  0.361
2005 Griekspoor A, Zwart W, Neefjes J. Presenting antigen presentation in living cells using biophysical techniques Current Opinion in Microbiology. 8: 338-343. PMID 15939359 DOI: 10.1016/J.Mib.2005.04.007  0.33
2005 De Almeida SF, Carvalho IF, Cardoso CS, Cordeiro JV, Azevedo JE, Neefjes J, De Sousa M. HFE cross-talks with the MHC class I antigen presentation pathway Blood. 106: 971-977. PMID 15840699 DOI: 10.1182/Blood-2004-12-4640  0.46
2005 Marsman M, Jordens I, Griekspoor A, Neefjes J. Chaperoning antigen presentation by MHC class II molecules and their role in oncogenesis Advances in Cancer Research. 93: 129-158. PMID 15797446 DOI: 10.1016/S0065-230X(05)93004-2  0.419
2005 Koppers-Lalic D, Reits EAJ, Ressing ME, Lipinska AD, Abele R, Koch J, Rezende MM, Admiraal P, Van Leeuwen D, Bienkowska-Szewczyk K, Mettenleiter TC, Rijsewijk FAM, Tampé R, Neefjes J, Wiertz EJHJ. Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing Proceedings of the National Academy of Sciences of the United States of America. 102: 5144-5149. PMID 15793001 DOI: 10.1073/Pnas.0501463102  0.449
2005 Neijssen J, Herberts C, Drijfhout JW, Reits E, Janssen L, Neefjes J. Cross-presentation by intercellular peptide transfer through gap junctions Nature. 434: 83-88. PMID 15744304 DOI: 10.1038/Nature03290  0.42
2005 Zwart W, Griekspoor A, Kuijl C, Marsman M, Van Rheenen J, Janssen H, Calafat J, Van Ham M, Janssen L, Van Lith M, Jalink K, Neefjes J. Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape Immunity. 22: 221-233. PMID 15723810 DOI: 10.1016/J.Immuni.2005.01.006  0.439
2004 Reits E, Neijssen J, Herberts C, Benckhuijsen W, Janssen L, Drijfhout JW, Neefjes J. A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation Immunity. 20: 495-506. PMID 15084277 DOI: 10.1016/S1074-7613(04)00074-3  0.421
2004 Marsman M, Jordens I, Kuijl C, Janssen L, Neefjes J. Dynein-mediated vesicle transport controls intracellular Salmonella replication Molecular Biology of the Cell. 15: 2954-2964. PMID 15064357 DOI: 10.1091/Mbc.E03-08-0614  0.327
2003 Yewdell JW, Reits E, Neefjes J. Making sense of mass destruction: Quantitating MHC class I antigen presentation Nature Reviews Immunology. 3: 952-961. PMID 14647477 DOI: 10.1038/Nri1250  0.457
2003 Ressing ME, Van Leeuwen D, Verreck FAW, Gomez R, Heemskerk B, Toebes M, Mullen MM, Jardetzky TS, Longnecker R, Schilham MW, Ottenhoff THM, Neefjes J, Schumacher TN, Hutt-Fletcher LM, Wiertz EJHJ. Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition Proceedings of the National Academy of Sciences of the United States of America. 100: 11583-11588. PMID 14504389 DOI: 10.1073/Pnas.2034960100  0.6
2003 van Lith M, van Ham M, Neefjes J. Stable expression of MHC class I heavy chain/HLA-DO complexes at the plasma membrane European Journal of Immunology. 33: 1145-1151. PMID 12731039 DOI: 10.1002/Eji.200323472  0.436
2003 Herberts C, Reits E, Neefjes J. Proteases, proteases and proteases for presentation Nature Immunology. 4: 306-308. PMID 12660727 DOI: 10.1038/Ni0403-306  0.368
2003 Reits E, Griekspoor A, Neijssen J, Groothuis T, Jalink K, Van Veelen P, Janssen H, Calafat J, Drijfhout JW, Neefjes J. Peptide Diffusion, Protection, and Degradation in Nuclear and Cytoplasmic Compartments before Antigen Presentation by MHC Class I Immunity. 18: 97-108. PMID 12530979 DOI: 10.1016/S1074-7613(02)00511-3  0.398
2002 Van Lith M, Van Ham M, Neefjes J. Novel polymorphisms in HLA-DOA and HLA-DOB in B-cell malignancies Immunogenetics. 54: 591-595. PMID 12439622 DOI: 10.1007/S00251-002-0500-6  0.375
2002 Reits E, Griekspoor A, Neefjes J. Herpes viral proteins manipulating the peptide transporter TAP Current Topics in Microbiology and Immunology. 269: 75-83. PMID 12224517 DOI: 10.1007/978-3-642-59421-2_5  0.436
2002 Grommé M, Neefjes J. Antigen degradation or presentation by MHC class I molecules via classical and non-classical pathways Molecular Immunology. 39: 181-202. PMID 12200050 DOI: 10.1016/S0161-5890(02)00101-3  0.449
2002 Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, Neefjes J, Baier G, Abraham RT, Altman A. Translocation of PKCθ in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C Journal of Cell Biology. 157: 253-263. PMID 11956228 DOI: 10.1083/Jcb.200201097  0.315
2001 Neefjes J. Determining protein transport to the plasma membrane Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 15.4. PMID 18228331 DOI: 10.1002/0471143030.Cb1504S05  0.316
2001 Roucard C, Thomas C, Pasquier MA, Trowsdale J, Sotto JJ, Neefjes J, Van Ham M. In vivo and in vitro modulation of HLA-DM and HLA-DO is induced by B lymphocyte activation Journal of Immunology. 167: 6849-6858. PMID 11739502 DOI: 10.4049/Jimmunol.167.12.6849  0.405
2001 Schüller S, Neefjes J, Ottenhoff T, Thole J, Young D. Coronin is involved in uptake of Mycobacterium bovis BCG in human macrophages but not in phagosome maintenance Cellular Microbiology. 3: 785-793. PMID 11736991 DOI: 10.1046/J.1462-5822.2001.00155.X  0.369
2001 Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, Janssen H, Wubbolts R, Neefjes J. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors Current Biology. 11: 1680-1685. PMID 11696325 DOI: 10.1016/S0960-9822(01)00531-0  0.307
2001 Koppers-Lalic D, Rijsewijk FAM, Verschuren SBE, van Gaans-van den Brink JAM, Neisig A, Ressing ME, Neefjes J, Wiertz EJHJ. The UL41-encoded virion host shutoff (vhs) protein and vhs-independent mechanisms are responsible for down-regulation of MHC class I molecules by bovine herpesvirus 1 Journal of General Virology. 82: 2071-2081. PMID 11514716 DOI: 10.1099/0022-1317-82-9-2071  0.402
2001 Knuehl C, Spee P, Ruppert T, Kuckelkorn U, Henklein P, Neefjes J, Kloetzel PM. The murine cytomegalovirus pp89 immunodominant H-2Ld epitope is generated and translocated into the endoplasmic reticulum as an 11-mer precursor peptide Journal of Immunology. 167: 1515-1521. PMID 11466372 DOI: 10.4049/Jimmunol.167.3.1515  0.393
2001 Van Lith M, Van Ham M, Griekspoor A, Tjin E, Verwoerd D, Calafat J, Janssen H, Reits E, Pastoors L, Neefjes J. Regulation of MHC class II antigen presentation by sorting of recycling HLA-DM/DO and class II within the multivesicular body Journal of Immunology. 167: 884-892. PMID 11441095 DOI: 10.4049/Jimmunol.167.2.884  0.434
2001 Neisig A, Neefjes J. Application of one-dimensional isoelectric focusing to separate different major histocompatibility complex class I alleles and determine their allelic interactions with transporter associated with antigen processing (TAP) Methods in Molecular Biology (Clifton, N.J.). 156: 153-163. PMID 11068757 DOI: 10.1385/1-59259-062-4:153  0.36
2000 Reits EAJ, Griekspoor AC, Neefjes J. How does TAP pump peptides? Insights from DNA repair and traffic ATPases Immunology Today. 21: 598-600. PMID 11114418 DOI: 10.1016/S0167-5699(00)01720-5  0.363
2000 Van Ham M, Van Lith M, Griekspoor A, Neefjes J. What to do with HLA-DO? Immunogenetics. 51: 765-770. PMID 10970090 DOI: 10.1007/S002510000208  0.467
2000 Koopmann JO, Albring J, Hüter E, Bulbuc N, Spee P, Neefjes J, Hämmerling GJ, Momburg F. Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel Immunity. 13: 117-127. PMID 10933400 DOI: 10.1016/S1074-7613(00)00013-3  0.381
2000 Singh-Jasuja H, Toes REM, Spee P, Münz C, Hilf N, Schoenberger SP, Ricciardi-Castagnoli P, Neefjes J, Rammensee HG, Arnold-Schild D, Schild H. Cross-presentation of glycoprotein 96-associated antigens: On major histocompatibility complex class I molecules requires receptor-mediated endocytosis Journal of Experimental Medicine. 191: 1965-1974. PMID 10839811 DOI: 10.1084/Jem.191.11.1965  0.44
2000 Reits EAJ, Vos JC, Grammé M, Neefjes J. The major substrates for TAP in vivo are derived from newly synthesized proteins Nature. 404: 774-778. PMID 10783892 DOI: 10.1038/35008103  0.433
2000 Van Marieke H, Van Lith M, Lillemeier B, Tjin E, Grüneberg U, Rahman D, Pastoors L, Van Meijgaarden K, Roucard C, Trowsdale J, Ottenhoff T, Pappin D, Neefjes J. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO Journal of Experimental Medicine. 191: 1127-1135. PMID 10748231 DOI: 10.1084/Jem.191.7.1127  0.478
2000 Vos JC, Reits EAJ, Wojcik-Jacobs E, Neefjes J. Head-head/tail-tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP Current Biology. 10: 1-7. PMID 10660295 DOI: 10.1016/S0960-9822(99)00257-2  0.307
1999 Wubbolts R, Neefjes J. Intracellular transport and peptide loading of MHC class II molecules: Regulation by chaperones and motors Immunological Reviews. 172: 189-208. PMID 10631947 DOI: 10.1111/J.1600-065X.1999.Tb01366.X  0.441
1999 Andersen MH, Bonfill JE, Neisig A, Arsequell G, Søndergaard I, Neefjes J, Zeuthen J, Elliott T, Haurum JS. Phosphorylated peptides can be transported by TAP molecules, presented by class I MHC molecules, and recognized by phosphopeptide-specific CTL Journal of Immunology. 163: 3812-3818. PMID 10490979  0.333
1999 Grommé M, Uytdehaag FGCM, Janssen H, Calafat J, Van Binnendijk RS, Kenter MJH, Tulp A, Verwoerd D, Neefjes J. Recycling MHC class I molecules and endosomal peptide loading Proceedings of the National Academy of Sciences of the United States of America. 96: 10326-10331. PMID 10468607 DOI: 10.1073/Pnas.96.18.10326  0.468
1999 Spee P, Subjeck J, Neefjes J. Identification of novel peptide binding proteins in the endoplasmic reticulum: ERp72, calnexin, and grp170 Biochemistry. 38: 10559-10566. PMID 10441153 DOI: 10.1021/Bi990321R  0.355
1999 Haurum JS, Høier IB, Arsequell G, Neisig A, Valencia G, Zeuthen J, Neefjes J, Elliott T. Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivo Journal of Experimental Medicine. 190: 145-150. PMID 10429679 DOI: 10.1084/Jem.190.1.145  0.443
1999 Neefjes J. CIIV, MIIC and other compartments for MHC class II loading European Journal of Immunology. 29: 1421-1425. PMID 10359095 DOI: 10.1002/(Sici)1521-4141(199905)29:05<1421::Aid-Immu1421>3.0.Co;2-C  0.404
1999 Fernandez-Borja M, Wubbolts R, Calafat J, Janssen H, Divecha N, Dusseljee S, Neefjes J. Multivesicular body morphogenesis requires phosphatidylinositol 3-kinase activity Current Biology. 9: 55-58. PMID 9889123 DOI: 10.1016/S0960-9822(99)80048-7  0.336
1998 Vierboom MP, Feltkamp MC, Neisig A, Drijfhout JW, ter Schegget J, Neefjes JJ, Melief CJ, Kast WM. Peptide vaccination with an anchor-replaced CTL epitope protects against human papillomavirus type 16-induced tumors expressing the wild-type epitope. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 399-408. PMID 9807734 DOI: 10.1097/00002371-199811000-00001  0.308
1998 Benham AM, Grommé M, Neefjes J. Allelic differences in the relationship between proteasome activity and MHC class I peptide loading Journal of Immunology. 161: 83-89. PMID 9647210  0.346
1997 Benham AM, Neefjes JJ. Proteasome activity limits the assembly of MHC class I molecules after IFN-gamma stimulation. Journal of Immunology (Baltimore, Md. : 1950). 159: 5896-904. PMID 9550386  0.348
1997 Koppelman B, Neefjes JJ, de Vries JE, de Waal Malefyt R. Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling. Immunity. 7: 861-71. PMID 9430231 DOI: 10.1016/S1074-7613(00)80404-5  0.319
1997 Van Ham SM, Tjin EPM, Lillemeier BF, Grüneberg U, Van Meijgaarden KE, Pastoors L, Verwoerd D, Tulp A, Canas B, Rahman D, Ottenhoff THM, Pappin DJC, Trowsdale J, Neefjes J. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading Current Biology. 7: 950-957. PMID 9382849 DOI: 10.1016/S0960-9822(06)00414-3  0.44
1997 Spee P, Neefjes J. TAP-translocated peptides specifically bind proteins in the endoplasmic reticulum, including gp96, protein disulfide isomerase and calreticulin European Journal of Immunology. 27: 2441-2449. PMID 9341791 DOI: 10.1002/Eji.1830270944  0.379
1997 Tan MC, Mommaas AM, Drijfhout JW, Jordens R, Onderwater JJ, Verwoerd D, Mulder AA, van der Heiden AN, Scheidegger D, Oomen LC, Ottenhoff TH, Tulp A, Neefjes JJ, Koning F. Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells. European Journal of Immunology. 27: 2426-35. PMID 9341789 DOI: 10.1002/eji.1830270942  0.319
1997 Khanna R, Burrows SR, Neisig A, Neefjes J, Moss DJ, Silins SL. Hierarchy of Epstein-Barr virus-specific cytotoxic T-cell responses in individuals carrying different subtypes of an HLA allele: Implications for epitope-based antiviral vaccines Journal of Virology. 71: 7429-7435. PMID 9311821 DOI: 10.1128/Jvi.71.10.7429-7435.1997  0.377
1997 Grommé M, Van der Valk R, Sliedregt K, Vernie L, Liskamp R, Hämmerling G, Koopmann JO, Momburg F, Neefjes J. The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics European Journal of Immunology. 27: 898-904. PMID 9130642 DOI: 10.1002/Eji.1830270415  0.386
1997 Cerundolo V, Benham A, Braud V, Mukherjee S, Gould K, Macino B, Neefjes J, Townsend A. The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells European Journal of Immunology. 27: 336-341. PMID 9022037 DOI: 10.1002/Eji.1830270148  0.391
1997 Wubbolts R, Fernandez-Bona M, Neefjes J. MHC class II molecules: Transport pathways for antigen presentation Trends in Cell Biology. 7: 115-118. DOI: 10.1016/S0962-8924(97)01000-3  0.471
1997 Banga JP, Verwoerd D, Tremble J, Christie MR, Vlug A, Neefjes J, Tulp A. Influence of autoantibody on in vitro and in vivo antigen processing by human B cell lines secreting IgG antibody to the islet cell antigen glutamic acid decarboxylase-65 Immunology Letters. 56: 370. DOI: 10.1016/S0165-2478(97)86495-4  0.319
1997 Khanna R, Burrows SR, Neisig A, Neefjes J, Silins SL. Hierarchy of virus-specific CTL responses in individuals carrying different subtypes of a single HLA allele: influence of peptide affinity and intracellular transport of HLA molecules Immunology Letters. 56: 244. DOI: 10.1016/S0165-2478(97)85973-1  0.404
1996 Neefjes JJ. Antigen presentation by MHC class I and II molecules. Immunobiology. 195: 456-60. PMID 8933150 DOI: 10.1016/S0171-2985(96)80015-5  0.302
1996 Volkmann A, Neefjes J, Stockinger B. A conditionally immortalized dendritic cell line which differentiates in contact with T cells or T cell-derived cytokines European Journal of Immunology. 26: 2565-2572. PMID 8921940 DOI: 10.1002/Eji.1830261105  0.375
1996 Wubbolts R, Fernandez-Borja M, Oomen L, Verwoerd D, Janssen H, Calafat J, Tulp A, Dusseljee S, Neefjes J. Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface Journal of Cell Biology. 135: 611-622. PMID 8909537 DOI: 10.1083/Jcb.135.3.611  0.43
1996 Lewis JW, Neisig A, Neefjes J, Elliott T. Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP. Current Biology : Cb. 6: 873-83. PMID 8805302 DOI: 10.1016/S0960-9822(02)00611-5  0.463
1996 Ossendorp F, Eggers M, Neisig A, Ruppert T, Groettrup M, Sijts A, Mengedé E, Kloetzel PM, Neefjes J, Koszinowski U, Melief C. A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation Immunity. 5: 115-124. PMID 8769475 DOI: 10.1016/S0165-2478(97)85962-7  0.367
1996 Fernandez-Borja M, Verwoerd D, Sanderson F, Aerts H, Trowsdale J, Tulp A, Neefjes J. HLA-DM and MHC class II molecules co-distribute with peptidase-containing lysosomal subcompartments International Immunology. 8: 625-640. PMID 8671650 DOI: 10.1093/Intimm/8.5.625  0.439
1996 Neisig A, Wubbolts R, Zang X, Melief C, Neefjes J. Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing Journal of Immunology. 156: 3196-3206. PMID 8617941  0.329
1996 Sanderson F, Thomas C, Neefjes J, Trowsdale J. Association between HLA-DM and HLA-DR in vivo Immunity. 4: 87-96. PMID 8574855 DOI: 10.1016/S1074-7613(00)80301-5  0.406
1996 Benham A, Neefjes J. The effect of lactacystin on antigen presentation by MHC Class I molecules Biochemical Society Transactions. 24: 629S. DOI: 10.1042/Bst024629Sc  0.41
1995 Neisig A, Roelse J, Sijts AJ, Ossendorp F, Feltkamp MC, Kast WM, Melief CJ, Neefjes JJ. Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. Journal of Immunology (Baltimore, Md. : 1950). 154: 1273-9. PMID 7822796  0.307
1995 Kleijmeer MJ, Ossevoort MA, van Veen CJ, van Hellemond JJ, Neefjes JJ, Kast WM, Melief CJ, Geuze HJ. MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 154: 5715-24. PMID 7751623  0.302
1995 Neefjes J, Gottfried E, Roelse J, Gromme M, Obst R, Hammerling GJ, Momburg F. Analysis of the fine specificity of rat, mouse and human TAP peptide transporters European Journal of Immunology. 25: 1133-1136. PMID 7737286 DOI: 10.1002/Eji.1830250444  0.388
1995 Peters PJ, Raposo G, Neefjes JJ, Oorschot V, Leijendekker RL, Geuze HJ, Ploegh HL. Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes. The Journal of Experimental Medicine. 182: 325-34. PMID 7629497 DOI: 10.1084/Jem.182.2.325  0.482
1995 Benham A, Tulp A, Neefjes J. Synthesis and assembly of MHC-peptide complexes Immunology Today. 16: 359-362. PMID 7576076 DOI: 10.1016/0167-5699(95)80157-X  0.447
1995 Gournier H, Pascolo S, Siegrist CA, Jehan J, Pérarnau B, Garcia Z, Rose T, Neefjes J, Lemonnier FA. Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps. European Journal of Immunology. 25: 2019-26. PMID 7542602 DOI: 10.1002/Eji.1830250733  0.439
1994 Momburg F, Neefjes JJ, Hämmerling GJ. Peptide selection by MHC-encoded TAP transporters. Current Opinion in Immunology. 6: 32-7. PMID 8172678 DOI: 10.1016/0952-7915(94)90030-2  0.325
1994 Momburg F, Roelse J, Howard JC, Butcher GW, Hämmerling GJ, Neefjes JJ. Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature. 367: 648-51. PMID 8107849 DOI: 10.1038/367648A0  0.318
1994 Calafat J, Nijenhuis M, Janssen H, Tulp A, Dusseljee S, Wubbolts R, Neefjes J. Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures Journal of Cell Biology. 126: 967-977. PMID 8051215 DOI: 10.1083/Jcb.126.4.967  0.413
1994 Nijenhuis M, Neefjes J. Early events in the assembly of major histocompatibility complex class II heterotrimers from their free subunits. European Journal of Immunology. 24: 247-256. PMID 8020564 DOI: 10.1002/Eji.1830240139  0.343
1994 Sanderson F, Kleijmeer MJ, Kelly A, Verwoerd D, Tulp A, Neefjes JJ, Geuze HJ, Trowsdale J. Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science (New York, N.Y.). 266: 1566-9. PMID 7985027 DOI: 10.1126/science.7985027  0.344
1994 Roelse J, Grommé M, Momburg F, Hämmerling G, Neefjes J. Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling. The Journal of Experimental Medicine. 180: 1591-7. PMID 7964447 DOI: 10.1084/Jem.180.5.1591  0.4
1993 Bijlmakers MJ, Neefjes JJ, Wojcik-Jacobs EH, Ploegh HL. The assembly of H2-Kb class I molecules translated in vitro requires oxidized glutathione and peptide. European Journal of Immunology. 23: 1305-13. PMID 8500526 DOI: 10.1002/Eji.1830230618  0.478
1993 Neefjes JJ, Dierx J, Ploegh HL. The effect of anchor residue modifications on the stability of major histocompatibility complex class I-peptide interactions. European Journal of Immunology. 23: 840-5. PMID 8384560 DOI: 10.1002/Eji.1830230411  0.489
1993 Neefjes JJ, Momburg F, Hämmerling GJ. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science (New York, N.Y.). 261: 769-71. PMID 8342042 DOI: 10.1126/science.8342042  0.324
1993 Neefjes JJ, Hämmerling GJ, Momburg F. Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide. The Journal of Experimental Medicine. 178: 1971-80. PMID 8245776 DOI: 10.1084/jem.178.6.1971  0.307
1993 Neefjes JJ, Momburg F. Cell biology of antigen presentation. Current Opinion in Immunology. 5: 27-34. PMID 7680870 DOI: 10.1016/0952-7915(93)90077-6  0.358
1993 Viville S, Neefjes J, Lotteau V, Dierich A, Lemeur M, Ploegh H, Benoist C, Mathis D. Mice lacking the MHC class II-associated invariant chain. Cell. 72: 635-48. PMID 7679955 DOI: 10.1016/0092-8674(93)90081-Z  0.563
1992 Neefjes JJ, Ploegh HL. Intracellular transport of MHC class II molecules. Immunology Today. 13: 179-84. PMID 1642756 DOI: 10.1016/0167-5699(92)90123-O  0.529
1992 Kuijpers KC, van Kemenade FJ, Hooibrink B, Neefjes JJ, Lucas CJ, van Lier RA, Miedema F. HLA class I and II molecules present influenza virus antigens with different kinetics. European Journal of Immunology. 22: 2339-45. PMID 1516624 DOI: 10.1002/eji.1830220924  0.321
1992 Faber ED, Oosting R, Neefjes JJ, Ploegh HL, Meijer DK. Distribution and elimination of the glycosidase inhibitors 1-deoxymannojirimycin and N-methyl-1-deoxynojirimycin in the rat in vivo. Pharmaceutical Research. 9: 1442-50. PMID 1475231 DOI: 10.1023/A:1015810913257  0.317
1992 Neefjes JJ, Smit L, Gehrmann M, Ploegh HL. The fate of the three subunits of major histocompatibility complex class I molecules. European Journal of Immunology. 22: 1609-14. PMID 1318200 DOI: 10.1002/Eji.1830220639  0.507
1992 Neefjes JJ, Ploegh HL. Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes. The Embo Journal. 11: 411-6. PMID 1311249 DOI: 10.1002/J.1460-2075.1992.Tb05069.X  0.504
1992 Momburg F, Ortiz-Navarrete V, Neefjes J, Goulmy E, van de Wal Y, Spits H, Powis SJ, Butcher GW, Howard JC, Walden P. Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature. 360: 174-7. PMID 1299222 DOI: 10.1038/360174A0  0.461
1991 Peters PJ, Neefjes JJ, Oorschot V, Ploegh HL, Geuze HJ. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature. 349: 669-76. PMID 1847504 DOI: 10.1038/349669A0  0.517
1991 Neefjes JJ, Schumacher TN, Ploegh HL. Assembly and intracellular transport of major histocompatibility complex molecules. Current Opinion in Cell Biology. 3: 601-9. PMID 1837724 DOI: 10.1016/0955-0674(91)90029-X  0.646
1991 Schumacher TN, De Bruijn ML, Vernie LN, Kast WM, Melief CJ, Neefjes JJ, Ploegh HL. Peptide selection by MHC class I molecules. Nature. 350: 703-6. PMID 1708852 DOI: 10.1038/350703A0  0.636
1990 Neefjes JJ, De Bruijn ML, Boog CJ, Nieland JD, Boes J, Melief CJ, Ploegh HL. N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response. The Journal of Experimental Medicine. 171: 583-8. PMID 2303788 DOI: 10.1084/Jem.171.2.583  0.4
1990 Neefjes JJ, Hengeveld T, Tol O, Ploegh HL. Intracellular interactions of transferrin and its receptor during biosynthesis. The Journal of Cell Biology. 111: 1383-92. PMID 2211816 DOI: 10.1083/Jcb.111.4.1383  0.375
1990 Schumacher TN, Heemels MT, Neefjes JJ, Kast WM, Melief CJ, Ploegh HL. Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell. 62: 563-7. PMID 2199065 DOI: 10.1016/0092-8674(90)90020-F  0.647
1990 Ljunggren HG, Stam NJ, Ohlén C, Neefjes JJ, Höglund P, Heemels MT, Bastin J, Schumacher TN, Townsend A, Kärre K. Empty MHC class I molecules come out in the cold. Nature. 346: 476-80. PMID 2198471 DOI: 10.1038/346476A0  0.584
1990 Neefjes JJ, Stollorz V, Peters PJ, Geuze HJ, Ploegh HL. The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. Cell. 61: 171-83. PMID 2156628 DOI: 10.1016/0092-8674(90)90224-3  0.498
1990 NEEFJES JJ, PLOEGH HL. The Role of N-Linked Carbohydrates in Antigen Presentation Trends in Glycoscience and Glycotechnology. 2: 365-372. DOI: 10.4052/Tigg.2.365  0.375
1989 Boog CJ, Neefjes JJ, Boes J, Ploegh HL, Melief CJ. Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen-presenting cells. European Journal of Immunology. 19: 537-42. PMID 2785048 DOI: 10.1002/Eji.1830190319  0.499
1989 Masucci MG, Stam NJ, Torsteinsdottir S, Neefjes JJ, Klein G, Ploegh HL. Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines. Cellular Immunology. 120: 396-400. PMID 2541930 DOI: 10.1016/0008-8749(89)90207-4  0.394
1989 Neefjes JJ, Lindhout J, Broxterman HJ, van der Marel GA, van Boom JH, Ploegh HL. Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells. The Journal of Biological Chemistry. 264: 10271-5. PMID 2524494  0.36
1989 Doxiadis I, Krumbacher K, Neefjes JJ, Ploegh HL, Grosse-Wilde H. Biochemical evidence that the DLA-B locus codes for a class II determinant expressed on all canine peripheral blood lymphocytes. Experimental and Clinical Immunogenetics. 6: 219-24. PMID 2520676  0.44
1989 Rotteveel FT, Neefjes JJ, Ploegh HL, Lucas CJ. Influenza virus changes cell-surface glycoproteins including major histocompatibility complex determinants on lymphocytes. Human Immunology. 26: 199-213. PMID 2514159 DOI: 10.1016/0198-8859(89)90039-6  0.444
1989 BROXTERMAN HJG, NEEFJES JJ, VAN DER MAREL GA, PLOEGH HL, VAN BOOM JH. ChemInform Abstract: Synthesis of the Antibiotic 1,5-Dideoxy-1,5-imino-D-mannitol. Cheminform. 20. DOI: 10.1002/chin.198909319  0.302
1988 Bolscher JG, van der Bijl MM, Neefjes JJ, Hall A, Smets LA, Ploegh HL. Ras (proto)oncogene induces N-linked carbohydrate modification: temporal relationship with induction of invasive potential. The Embo Journal. 7: 3361-8. PMID 3061796 DOI: 10.1002/J.1460-2075.1988.Tb03208.X  0.347
1988 Neefjes JJ, Ploegh HL. Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association. European Journal of Immunology. 18: 801-10. PMID 2967765 DOI: 10.1002/Eji.1830180522  0.446
1988 Neefjes JJ, Verkerk JM, Broxterman HJ, van der Marel GA, van Boom JH, Ploegh HL. Recycling glycoproteins do not return to the cis-Golgi. The Journal of Cell Biology. 107: 79-87. PMID 2839522 DOI: 10.1083/Jcb.107.1.79  0.378
1988 BROXTERMAN HJG, VAN DER MAREL GA, NEEFJES JJ, PLOEGH HL, VAN BOOM JH. ChemInform Abstract: Synthesis of the Antibiotic 1,5-Dideoxy-1,5-imino-D-glucitol; Concomitant Formation of the D-Mannitol Analogue. Cheminform. 19. DOI: 10.1002/chin.198813351  0.301
1987 Rein RS, Seemann GH, Neefjes JJ, Hochstenbach FM, Stam NJ, Ploegh HL. Association with beta 2-microglobulin controls the expression of transfected human class I genes. Journal of Immunology (Baltimore, Md. : 1950). 138: 1178-83. PMID 3543123  0.41
1987 Gruters RA, Neefjes JJ, Tersmette M, de Goede RE, Tulp A, Huisman HG, Miedema F, Ploegh HL. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature. 330: 74-7. PMID 2959866 DOI: 10.1038/330074A0  0.363
1986 Neefjes JJ, Doxiadis I, Stam NJ, Beckers CJ, Ploegh HL. An analysis of class I antigens of man and other species by one-dimensional IEF and immunoblotting. Immunogenetics. 23: 164-71. PMID 3957414 DOI: 10.1007/Bf00373817  0.439
1986 Neefjes JJ, Hensen EJ, de Kroon TI, Ploegh HL. A biochemical characterization of feline MHC products: unusually high expression of class II antigens on peripheral blood lymphocytes. Immunogenetics. 23: 341-7. PMID 3458670 DOI: 10.1007/Bf00398799  0.479
1986 Neefjes JJ, Breur-Vriesendorp BS, van Seventer GA, Iványi P, Ploegh HL. An improved biochemical method for the analysis of HLA-class I antigens. Definition of new HLA-class I subtypes. Human Immunology. 16: 169-81. PMID 3087921 DOI: 10.1016/0198-8859(86)90046-7  0.442
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