Sherry F. Queener - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Pharmacology, Microbiology Biology, Molecular Biology

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Year Citation  Score
2013 Zaware N, Sharma H, Yang J, Devambatla RK, Queener SF, Anderson KS, Gangjee A. Discovery of potent and selective inhibitors of Toxoplasma gondii thymidylate synthase for opportunistic infections. Acs Medicinal Chemistry Letters. 4: 1148-1151. PMID 24470841 DOI: 10.1021/ml400208v  0.4
2013 Queener SF, Cody V, Pace J, Torkelson P, Gangjee A. Trimethoprim resistance of dihydrofolate reductase variants from clinical isolates of Pneumocystis jirovecii. Antimicrobial Agents and Chemotherapy. 57: 4990-8. PMID 23896474 DOI: 10.1128/AAC.01161-13  0.4
2013 Gangjee A, Namjoshi OA, Raghavan S, Queener SF, Kisliuk RL, Cody V. Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; application of Buchwald-Hartwig aminations of heterocycles. Journal of Medicinal Chemistry. 56: 4422-41. PMID 23627352 DOI: 10.1021/jm400086g  0.4
2013 Cody V, Pace J, Queener SF, Adair OO, Gangjee A. Kinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants. Antimicrobial Agents and Chemotherapy. 57: 2669-77. PMID 23545530 DOI: 10.1128/AAC.00172-13  0.4
2013 Konrad C, Queener SF, Wek RC, Sullivan WJ. Inhibitors of eIF2α dephosphorylation slow replication and stabilize latency in Toxoplasma gondii. Antimicrobial Agents and Chemotherapy. 57: 1815-22. PMID 23380722 DOI: 10.1128/AAC.01899-12  0.4
2011 Cody V, Pace J, Piraino J, Queener SF. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. Journal of Structural Biology. 176: 52-9. PMID 21684339 DOI: 10.1016/j.jsb.2011.06.001  0.4
2010 Gibau GS, Foertsch J, Blum J, Brutkiewicz R, Queener S, Roman A, Rhodes S, Sturek M, Wilkes D, Broxmeyer H. Diversifying Biomedical Training: A Synergistic Intervention. Journal of Women and Minorities in Science and Engineering. 16: 215-235. PMID 21796238 DOI: 10.1615/JWomenMinorScienEng.v16.i3.20  0.4
2010 Joyce BR, Queener SF, Wek RC, Sullivan WJ. Phosphorylation of eukaryotic initiation factor-2{alpha} promotes the extracellular survival of obligate intracellular parasite Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America. 107: 17200-5. PMID 20855600 DOI: 10.1073/pnas.1007610107  0.4
2010 Bag S, Tawari NR, Degani MS, Queener SF. Design, synthesis, biological evaluation and computational investigation of novel inhibitors of dihydrofolate reductase of opportunistic pathogens. Bioorganic & Medicinal Chemistry. 18: 3187-97. PMID 20363634 DOI: 10.1016/j.bmc.2010.03.031  0.4
2010 Gangjee A, Lin X, Biondo LR, Queener SF. CoMFA analysis of tgDHFR and rlDHFR based on antifolates with 6-5 fused ring system using the all-orientation search (AOS) routine and a modified cross-validated r(2)-guided region selection (q(2)-GRS) routine and its initial application. Bioorganic & Medicinal Chemistry. 18: 1684-701. PMID 20117005 DOI: 10.1016/j.bmc.2009.12.066  0.4
2010 Gangjee A, Jain HD, Phan J, Guo X, Queener SF, Kisliuk RL. 2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors. Bioorganic & Medicinal Chemistry. 18: 953-61. PMID 20056546 DOI: 10.1016/j.bmc.2009.11.029  0.4
2010 Bag S, Tawari NR, Queener SF, Degani MS. Synthesis and biological evaluation of biguanide and dihydrotriazine derivatives as potential inhibitors of dihydrofolate reductase of opportunistic microorganisms. Journal of Enzyme Inhibition and Medicinal Chemistry. 25: 331-9. PMID 19874136 DOI: 10.3109/14756360903179443  0.4
2009 Gangjee A, Li W, Lin L, Zeng Y, Ihnat M, Warnke LA, Green DW, Cody V, Pace J, Queener SF. Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorganic & Medicinal Chemistry. 17: 7324-36. PMID 19748785 DOI: 10.1016/j.bmc.2009.08.044  0.4
2009 Pedró Rosa LE, Reddy DR, Queener SF, Miller LW. Selective antifolates for chemically labeling proteins in mammalian cells. Chembiochem : a European Journal of Chemical Biology. 10: 1462-4. PMID 19437525 DOI: 10.1002/cbic.200900152  0.4
2009 Cody V, Pace J, Makin J, Piraino J, Queener SF, Rosowsky A. Correlations of inhibitor kinetics for Pneumocystis jirovecii and human dihydrofolate reductase with structural data for human active site mutant enzyme complexes. Biochemistry. 48: 1702-11. PMID 19196009 DOI: 10.1021/bi801960h  0.4
2009 Gangjee A, Pagley OOAM, Queener SF. N9-substituted 2,4-diaminoquinazolines: Synthesis and biological evaluation of lipophilic inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase (Journal of Medicinal Chemistry (2008) 51, (6196) DOI: 10.1021/jm800694g) Journal of Medicinal Chemistry. 52: 4979. DOI: 10.1021/jm900938h  0.4
2008 Gangjee A, Adair OO, Pagley M, Queener SF. N9-substituted 2,4-diaminoquinazolines: synthesis and biological evaluation of lipophilic inhibitors of pneumocystis carinii and toxoplasma gondii dihydrofolate reductase. Journal of Medicinal Chemistry. 51: 6195-200. PMID 18771252 DOI: 10.1021/jm800694g  0.4
2008 Cody V, Mao Q, Queener SF. Recombinant bovine dihydrofolate reductase produced by mutagenesis and nested PCR of murine dihydrofolate reductase cDNA. Protein Expression and Purification. 62: 104-10. PMID 18672067 DOI: 10.1016/j.pep.2008.07.001  0.4
2008 Gangjee A, Jain HD, Queener SF, Kisliuk RL. The effect of 5-alkyl modification on the biological activity of pyrrolo[2,3-d]pyrimidine containing classical and nonclassical antifolates as inhibitors of dihydrofolate reductase and as antitumor and/or antiopportunistic infection agents. Journal of Medicinal Chemistry. 51: 4589-600. PMID 18605720 DOI: 10.1021/jm800244v  0.4
2008 Mui EJ, Schiehser GA, Milhous WK, Hsu H, Roberts CW, Kirisits M, Muench S, Rice D, Dubey JP, Fowble JW, Rathod PK, Queener SF, Liu SR, Jacobus DP, McLeod R. Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo. Plos Neglected Tropical Diseases. 2: e190. PMID 18320016 DOI: 10.1371/journal.pntd.0000190  0.4
2007 Reynolds RC, Campbell SR, Fairchild RG, Kisliuk RL, Micca PL, Queener SF, Riordan JM, Sedwick WD, Waud WR, Leung AK, Dixon RW, Suling WJ, Borhani DW. Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation. Journal of Medicinal Chemistry. 50: 3283-9. PMID 17569517 DOI: 10.1021/jm0701977  0.4
2007 Gangjee A, Zeng Y, Talreja T, McGuire JJ, Kisliuk RL, Queener SF. Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates. Journal of Medicinal Chemistry. 50: 3046-53. PMID 17552508 DOI: 10.1021/jm070165j  0.4
2007 Smith AT, Livingston MR, Mai A, Filetici P, Queener SF, Sullivan WJ. Quinoline derivative MC1626, a putative GCN5 histone acetyltransferase (HAT) inhibitor, exhibits HAT-independent activity against Toxoplasma gondii. Antimicrobial Agents and Chemotherapy. 51: 1109-11. PMID 17178801 DOI: 10.1128/AAC.01256-06  0.4
2006 Gangjee A, Yang J, Queener SF. Novel non-classical C9-methyl-5-substituted-2,4-diaminopyrrolo[2,3-d]pyrimidines as potential inhibitors of dihydrofolate reductase and as anti-opportunistic agents. Bioorganic & Medicinal Chemistry. 14: 8341-51. PMID 17010625 DOI: 10.1016/j.bmc.2006.09.008  0.4
2006 Gangjee A, Wang Y, Queener SF, Kisliuk RL. Synthesis of 2,6-diamino-5-[(2-substituted phenylamino)ethyl]pyrimidin- 4(3H)-one as inhibitors of folate metabolizing enzymes Journal of Heterocyclic Chemistry. 43: 1523-1531. DOI: 10.1002/jhet.5570430615  0.4
2005 Chan DC, Fu H, Forsch RA, Queener SF, Rosowsky A. Design, synthesis, and antifolate activity of new analogues of piritrexim and other diaminopyrimidine dihydrofolate reductase inhibitors with omega-carboxyalkoxy or omega-carboxy-1-alkynyl substitution in the side chain. Journal of Medicinal Chemistry. 48: 4420-31. PMID 15974594 DOI: 10.1021/jm0581718  0.4
2005 Sullivan WJ, Dixon SE, Li C, Striepen B, Queener SF. IMP dehydrogenase from the protozoan parasite Toxoplasma gondii. Antimicrobial Agents and Chemotherapy. 49: 2172-9. PMID 15917510 DOI: 10.1128/AAC.49.6.2172-2179.2005  0.4
2005 Cody V, Chisum K, Pope C, Queener SF. Purification and characterization of human-derived Pneumocystis jirovecii dihydrofolate reductase expressed in Sf21 insect cells and in Escherichia coli. Protein Expression and Purification. 40: 417-23. PMID 15766885 DOI: 10.1016/j.pep.2004.12.028  0.4
2005 Gangjee A, Jain HD, Queener SF. Design, synthesis and biological evaluation of 2,4-diamino-6-methyl-5- substitutedpyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors Journal of Heterocyclic Chemistry. 42: 589-594. DOI: 10.1002/CHIN.200541160  0.4
2005 Gangjee A, Ye Z, Queener SF. Synthesis of three carbon atom bridged 2,4-diaminopyrrolo[2,3-d]- pyrimidines as nonclassical dihydrofolate reductase inhibitors Journal of Heterocyclic Chemistry. 42: 1127-1133.  0.4
2004 Gangjee A, Lin X, Queener SF. Design, synthesis, and biological evaluation of 2,4-diamino-5-methyl-6-substituted-pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors. Journal of Medicinal Chemistry. 47: 3689-92. PMID 15214795 DOI: 10.1021/jm0306327  0.4
2004 Rosowsky A, Fu H, Chan DC, Queener SF. Synthesis of 2,4-diamino-6-[2'-O-(omega-carboxyalkyl)oxydibenz[b,f]azepin-5-yl]methylpteridines as potent and selective inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductase. Journal of Medicinal Chemistry. 47: 2475-85. PMID 15115391 DOI: 10.1021/jm030599o  0.4
2004 Graffner-Nordberg M, Kolmodin K, Aqvist J, Queener SF, Hallberg A. Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 22: 43-54. PMID 15113582 DOI: 10.1016/j.ejps.2004.02.004  0.4
2004 Cody V, Luft JR, Pangborn W, Gangjee A, Queener SF. Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallographica. Section D, Biological Crystallography. 60: 646-55. PMID 15039552 DOI: 10.1107/S0907444904002094  0.4
2004 Forsch RA, Queener SF, Rosowsky A. Preliminary in vitro studies on two potent, water-soluble trimethoprim analogues with exceptional species selectivity against dihydrofolate reductase from Pneumocystis carinii and Mycobacterium avium. Bioorganic & Medicinal Chemistry Letters. 14: 1811-5. PMID 15026078 DOI: 10.1016/j.bmcl.2004.03.026  0.4
2004 Rosowsky A, Forsch RA, Sibley CH, Inderlied CB, Queener SF. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity. Journal of Medicinal Chemistry. 47: 1475-86. PMID 14998335 DOI: 10.1021/jm030438k  0.4
2003 Gangjee A, Adair OO, Queener SF. Synthesis and biological evaluation of 2,4-diamino-6-(arylaminomethyl)pyrido[2,3-d]pyrimidines as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase and as antiopportunistic infection and antitumor agents. Journal of Medicinal Chemistry. 46: 5074-82. PMID 14584957 DOI: 10.1021/jm030312n  0.4
2003 Donkor IO, Li H, Queener SF. Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines. European Journal of Medicinal Chemistry. 38: 605-11. PMID 12832132 DOI: 10.1002/CHIN.200343134  0.4
2003 Sullivan WJ, Monroy MA, Bohne W, Nallani KC, Chrivia J, Yaciuk P, Smith CK, Queener SF. Molecular cloning and characterization of an SRCAP chromatin remodeling homologue in Toxoplasma gondii. Parasitology Research. 90: 1-8. PMID 12743798 DOI: 10.1007/s00436-002-0814-1  0.4
2003 Rosowsky A, Forsch RA, Queener SF. Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS. Journal of Medicinal Chemistry. 46: 1726-36. PMID 12699390 DOI: 10.1021/jm020466n  0.4
2003 Rosowsky A, Chen H, Fu H, Queener SF. Synthesis of new 2,4-Diaminopyrido[2,3-d]pyrimidine and 2,4-Diaminopyrrolo[2,3-d]pyrimidine inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductase. Bioorganic & Medicinal Chemistry. 11: 59-67. PMID 12467708 DOI: 10.1016/S0968-0896(02)00325-5  0.4
2003 Gangjee A, Lin X, Queener SF. 7-Methyl trimethoprim analogues as inhibitors of the folate metabolizing enzymes Journal of Heterocyclic Chemistry. 40: 507-512.  0.4
2002 Cody V, Galitsky N, Luft JR, Pangborn W, Queener SF, Gangjee A. Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase. Acta Crystallographica. Section D, Biological Crystallography. 58: 1393-9. PMID 12198294 DOI: 10.1107/S0907444902010442  0.4
2002 Chan DC, Laughton CA, Queener SF, Stevens MF. Structural studies on bioactive compounds. Part 36: design, synthesis and biological evaluation of pyrimethamine-based antifolates against Pneumocystis carinii. Bioorganic & Medicinal Chemistry. 10: 3001-10. PMID 12110323 DOI: 10.1016/S0968-0896(02)00128-1  0.4
2002 Cody V, Galitsky N, Luft JR, Pangborn W, Rosowsky A, Queener SF. Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH. Acta Crystallographica. Section D, Biological Crystallography. 58: 946-54. PMID 12037296 DOI: 10.1107/S090744490200505X  0.4
2002 Rosowsky A, Forsch RA, Queener SF. Inhibition of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductases by 2,4-diamino-5-[2-methoxy-5-(omega-carboxyalkyloxy)benzyl]pyrimidines: marked improvement in potency relative to trimethoprim and species selectivity relative to piritrexim. Journal of Medicinal Chemistry. 45: 233-41. PMID 11754594 DOI: 10.1021/jm010407u  0.4
2001 Gangjee A, Adair O, Queener SF. Synthesis of 2,4-Diamino-6-(thioarylmethyl)pyrido[2,3-d]pyrimidines as dihydrofolate reductase inhibitors Bioorganic and Medicinal Chemistry. 9: 2929-2935. PMID 11597474 DOI: 10.1016/S0968-0896(01)00223-1  0.4
2001 Huang TL, Tao B, Quarshie Y, Queener SF, Donkor IO. N,N′-Bis[4-(N-alkylamidino)phenyl]homopiperazines as anti-Pneumocystis carinii agents Bioorganic and Medicinal Chemistry Letters. 11: 2679-2681. PMID 11591500 DOI: 10.1016/S0960-894X(01)00541-8  0.4
2001 Wang Y, Bruenn JA, Queener SF, Cody V. Isolation of rat dihydrofolate reductase gene and characterization of recombinant enzyme Antimicrobial Agents and Chemotherapy. 45: 2517-2523. PMID 11502523 DOI: 10.1128/AAC.45.9.2517-2523.2001  0.4
2001 Chan DCM, Laughton CA, Queener SF, Stevens MFG. Structural studies on bioactive compounds. 34.1 Design, synthesis, and biological evaluation of triazenyl-substituted pyrimethamine inhibitors of Pneumocystis carinii dihydrofolate reductase Journal of Medicinal Chemistry. 44: 2555-2564. PMID 11472209 DOI: 10.1021/jm0108698  0.4
2001 Graffner-Nordberg M, Kolmodin K, Åqvist J, Queener SF, Hallberg A. Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from pneumocystis carinii Journal of Medicinal Chemistry. 44: 2391-2402. PMID 11448221 DOI: 10.1021/jm010856u  0.4
2001 Gangjee A, Vidwans A, Elzein E, McGuire JJ, Queener SF, Kisliuk RL. Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines Journal of Medicinal Chemistry. 44: 1993-2003. PMID 11384244 DOI: 10.1021/jm0100382  0.4
2001 Ye D, Lee CH, Queener SF. Differential splicing of Pneumocystis carinii f. sp. carinii inosine 5'-monophosphate dehydrogenase pre-mRNA. Gene. 263: 151-8. PMID 11223253 DOI: 10.1016/S0378-1119(00)00577-1  0.4
2001 Gangjee A, Mavandadi F, Queener SF. Conformationally restricted tricyclic analogues of lipophilic pyrido[2,3-d]pyrimidine antifolates [1a,b] Journal of Heterocyclic Chemistry. 38: 213-220.  0.4
2001 Rosowsky A, Fu H, Queener SF. Synthesis of new 2,4-diamino-7H-pyrrolo[2,3-d]pyrimidines via the Taylor ring transformation/ring annulation strategy Journal of Heterocyclic Chemistry. 38: 1197-1202.  0.4
2000 Gangjee A, Yu J, McGuire JJ, Cody V, Galitsky N, Kisliuk RL, Queener SF. Design, synthesis, and x-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent Journal of Medicinal Chemistry. 43: 3837-3851. PMID 11052789 DOI: 10.1021/jm000200l  0.4
2000 Cody V, Chan D, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF, Laughton CA, Stevens MF. Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate. Biochemistry. 39: 3556-64. PMID 10736154 DOI: 10.1021/bi9924563  0.4
2000 Rosowsky A, Fu H, Queener SF. Synthesis of 2,4-diaminopyrido[2,3-d]pyrimidines and 2,4-diamino-quinazolines with bulky dibenz[b,f]azepine and dibenzo[a,d]-cycloheptene substituents at the 6-position as inhibitors of dihydrofolate reductases from Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium Journal of Heterocyclic Chemistry. 37: 921-926.  0.4
2000 Gangjee A, Dubash NP, Queener SF. The synthesis of new 2,4-diaminofuro[2,3-d]pyrimidines with 5-biphenyl, phenoxyphenyl and tricyclic substitutions as dihydrofolate reductase inhibitors Journal of Heterocyclic Chemistry. 37: 935-942.  0.4
2000 Chan D, Stevens MFG, Laughton CA, Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Selective inhibitors of Pneumocystis carinii dihydrofolate reductase via structure-based design Journal of Pharmacy and Pharmacology. 52: 226.  0.4
1999 Rosowsky A, Cody V, Galitsky N, Fu H, Papoulis AT, Queener SF. Structure-based design of selective inhibitors of dihydrofolate reductase: Synthesis and antiparasitic activity of 2,4-diaminopteridine analogues with a bridged diarylamine side chain Journal of Medicinal Chemistry. 42: 4853-4860. PMID 10579848 DOI: 10.1021/jm990331q  0.4
1999 Rosowsky A, Queener SF, Cody V. Inhibition of dihydrofolate reductases from Toxoplasma gondii, Pneumocystis carinii, and rat liver by rotationally restricted analogues of pyrimethamine and metoprine Drug Design and Discovery. 16: 25-40. PMID 10466054  0.4
1999 Gangjee A, Adair O, Queener SF. Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase inhibitors and antitumor agents: Synthesis and biological activities of 2,4- diamino-5-methyl-6-[(monosubstituted anilino)methyl]pyrido[2,3-d]pyrimidines Journal of Medicinal Chemistry. 42: 2447-2455. PMID 10395486 DOI: 10.1021/jm990079m  0.4
1999 Gangjee A, Mavandadi F, Kisliuk RL, Queener SF. Synthesis of classical and a nonclassical 2-amino-4-oxo-6-methyl-5- substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of thymidylate synthase Journal of Medicinal Chemistry. 42: 2272-2279. PMID 10377234 DOI: 10.1021/jm980586o  0.4
1999 Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+ Biochemistry. 38: 4303-4312. PMID 10194348 DOI: 10.1021/bi982728m  0.4
1999 Rosowsky A, Papoulis AT, Forsch RA, Queener SF. Synthesis and antiparasitic and antitumor activity of 2,4-diamino-6- (arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim Journal of Medicinal Chemistry. 42: 1007-1017. PMID 10090784 DOI: 10.1021/jm980572i  0.4
1999 Tao B, Huang TL, Zhang Q, Jackson L, Queener SF, Donkor IO. Synthesis and anti-Pneumocystis carinii activity of conformationally restricted analogues of pentamidine European Journal of Medicinal Chemistry. 34: 531-538. DOI: 10.1016/S0223-5234(99)80102-0  0.4
1999 Rosowsky A, Papoulis AT, Queener SF. One-step synthesis of novel 2,4-diaminopyrimidine antifolates from bridged alicyclic ketones and cyanoguanidine Journal of Heterocyclic Chemistry. 36: 723-728.  0.4
1998 Gangjee A, Zhu Y, Queener SF. 6-Substituted 2,4-diaminopyrido[3,2-d]pyrimidine analogues of piritrexim as inhibitors of dihydrofolate reductase from rat liver, Pneumocystis carinii, and Toxoplasma gondii and as antitumor agents Journal of Medicinal Chemistry. 41: 4533-4541. PMID 9804692 DOI: 10.1021/jm980206z  0.4
1998 Gangjee A, Vidwans AP, Vasudevan A, Queener SF, Kisliuk RL, Cody V, Li R, Galitsky N, Luft JR, Pangborn W. Structure-based design and synthesis of lipophilic 2,4-diamino-6- substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents Journal of Medicinal Chemistry. 41: 3426-3434. PMID 9719595 DOI: 10.1021/jm980081y  0.4
1998 Gangjee A, Elzein E, Queener SF, McGuire JJ. Synthesis and biological activities of tricyclic conformationally restricted tetrahydropyrido annulated furo[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases Journal of Medicinal Chemistry. 41: 1409-1416. PMID 9554874 DOI: 10.1021/jm9705420  0.4
1998 Gangjee A, Guo X, Queener SF, Cody V, Galitsky N, Luft JR, Pangborn W. Selective Pneumocystis carinii dihydrofolate reductase inhibitors: Design, synthesis, and biological evaluation of new 2,4-diamino-5- substituted-furo[2,3-d]pyrimidines Journal of Medicinal Chemistry. 41: 1263-1271. PMID 9548816 DOI: 10.1021/jm970537w  0.4
1998 Rosowsky A, Papoulis AT, Queener SF. 2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine analogues of trimethoprim as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Journal of Medicinal Chemistry. 41: 913-918. PMID 9526565 DOI: 10.1021/jm970614n  0.4
1997 Cody V, Galitsky N, Luft JR, Pangborn W, Gangjee A, Devraj R, Queener SF, Blakley RL. Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate. Acta Crystallographica. Section D, Biological Crystallography. 53: 638-49. PMID 15299851 DOI: 10.1107/S090744499700509X  0.4
1997 Bartlett MS, Queener SF, Shaw MM, Durant PJ, Lee CH, Smith JW. In vitro and in vivo models of Pneumocystis carinii. The Journal of Eukaryotic Microbiology. 44: 51S. PMID 9508437 DOI: 10.1111/j.1550-7408.1997.tb05772.x  0.4
1997 Rosowsky A, Papoulis AT, Queener SF. 2,4-Diaminothieno[2,3-d]pyrimidine lipophilic antifolates as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Journal of Medicinal Chemistry. 40: 3694-3699. PMID 9357537 DOI: 10.1021/jm970399a  0.4
1997 Robson C, Meek MA, Grunwaldt JD, Lambert PA, Queener SF, Schmidt D, Griffin RJ. Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents. Journal of Medicinal Chemistry. 40: 3040-8. PMID 9301666 DOI: 10.1021/jm970055k  0.4
1997 Gangjee A, Vasudevan A, Queener SF. Conformationally restricted analogues of trimethoprim: 2,6-diamino-8- substituted purines as potential dihydrofolate reductase inhibitors from Pneumocystis carinii and Toxoplasma gondii Journal of Medicinal Chemistry. 40: 3032-3039. PMID 9301665 DOI: 10.1021/jm970271t  0.4
1997 Gangjee A, Shi J, Queener SF. Synthesis and biological activities of conformationally restricted, tricyclic nonclassical antifolates as inhibitors of dihydrofolate reductases Journal of Medicinal Chemistry. 40: 1930-1936. PMID 9191971 DOI: 10.1021/jm960693n  0.4
1997 Stevens MF, Phillip KS, Rathbone DL, O'Shea DM, Queener SF, Schwalbe CH, Lambert PA. Structural studies on bioactive compounds. 28. Selective activity of triazenyl-substituted pyrimethamine derivatives against Pneumocystis carinii dihydrofolate reductase. Journal of Medicinal Chemistry. 40: 1886-93. PMID 9191966 DOI: 10.1021/jm970050n  0.4
1997 Gangjee A, Mavandadi F, Queener SF. Effect of N9-methylation and bridge atom variation on the activity of 5-substituted 2,4-diaminopyrrolo[2,3-d]pyrimidines against dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii Journal of Medicinal Chemistry. 40: 1173-1177. PMID 9089339 DOI: 10.1021/jm960717q  0.4
1997 Gangjee A, Vasudevan A, Queener SF. Synthesis and biological evaluation of nonclassical 2,4-diamino-5- methylpyrido[2,3-d]pyrimidines with novel side chain substituents as potential inhibitors of dihydrofolate reductases Journal of Medicinal Chemistry. 40: 479-485. PMID 9046338 DOI: 10.1021/jm960734f  0.4
1997 Gangjee A, Devraj R, Queener SF. Synthesis and dihydrofolate reductase inhibitory activities of 2,4- diamino-5-deaza and 2,4-diamino-5,10-dideaza lipophilic antifolates Journal of Medicinal Chemistry. 40: 470-478. PMID 9046337 DOI: 10.1021/jm9606913  0.4
1997 O'Gara MJ, Lee CH, Weinberg GA, Nott JM, Queener SF. IMP dehydrogenase from Pneumocystis carinii as a potential drug target. Antimicrobial Agents and Chemotherapy. 41: 40-8. PMID 8980752  0.4
1997 Queener SF, Bolvard LA. Identification of vimentin as a primaquine-binding protein from pneumocystis cakinii Faseb Journal. 11.  0.4
1997 Rosowsky A, Forsch RA, Queener SF, Bertino JR. Synthesis of 2,4-diaminopteridines with bulky lipophilic groups at the 6-position as inhibitors of Pneumocystis carinii, Toxoplasma gondii, and mammalian dihydrofolate reductase Pteridines. 8: 173-187.  0.4
1997 Zhang Q, White AT, Malbrue M, Huang TL, Queener SF, Donkor IO. Synthesis, anti-pneumocystis carinii activity, and DNA binding affinity of a new series of conformational constrained pentamidine congeners Faseb Journal. 11.  0.4
1996 Gangjee A, Mavandadi F, Kisliuk RL, McGuire JJ, Queener SF. 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as nonclassical antifolate inhibitors of thymidylate synthase Journal of Medicinal Chemistry. 39: 4563-4568. PMID 8917644 DOI: 10.1021/jm960097t  0.4
1996 Chio LC, Bolyard LA, Nasr M, Queener SF. Identification of a class of sulfonamides highly active against dihydropteroate synthase from Toxoplasma gondii, Pneumocystis carinii, and Mycobacterium avium Antimicrobial Agents and Chemotherapy. 40: 727-733. PMID 8851601  0.4
1996 Bartlett MS, Current WL, Goheen MP, Boylan CJ, Lee CH, Shaw MM, Queener SF, Smith JW. Semisynthetic echinocandins affect cell wall deposition of Pneumocystis carinii in vitro and in vivo. Antimicrobial Agents and Chemotherapy. 40: 1811-6. PMID 8843286  0.4
1996 Durant PJ, Bartlett MS, Shaw MM, Queener SF, Smith JW. Demonstration of esterase activity in Pneumocystis carinii by cleavage of 4-methylumbelliferyl substrates. The Journal of Eukaryotic Microbiology. 43: 45S. PMID 8822848  0.4
1996 Bartlett MS, Lu JJ, Lee CH, Durant PJ, Queener SF, Smith JW. Types of Pneumocystis carinii detected in air samples. The Journal of Eukaryotic Microbiology. 43: 44S. PMID 8822847  0.4
1996 Jackson HC, Biggadike K, McKilligin E, Kinsman OS, Queener SF, Lane A, Smith JE. 6,7-disubstituted 2,4-diaminopteridines: Novel inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Antimicrobial Agents and Chemotherapy. 40: 1371-1375. PMID 8726003  0.4
1996 Gangjee A, Vasudevan A, Queener SF, Kisliuk RL. 2,4-Diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases Journal of Medicinal Chemistry. 39: 1438-1446. PMID 8691474 DOI: 10.1021/jm960310l  0.4
1996 Piper JR, Johnson CA, Krauth CA, Carter RL, Hosmer CA, Queener SF, Borotz SE, Pfefferkorn ER. Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations. Journal of Medicinal Chemistry. 39: 1271-80. PMID 8632434 DOI: 10.1021/jm950760y  0.4
1996 Gangjee A, Zhu Y, Queener SF, Francom P, Broom AD. Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii Journal of Medicinal Chemistry. 39: 1836-1845. PMID 8627607 DOI: 10.1021/jm950918e  0.4
1996 Delia TJ, Nagarajan A, Queener SF, Bartlet MS. Ring-based analogues of pentamidine versus P. carinii pneumonia in culture Bioorganic and Medicinal Chemistry Letters. 6: 2367-2370. DOI: 10.1016/0960-894X(96)00427-1  0.4
1996 Huang TL, Zhang Q, White AT, Queener SF, Bartlett MS, Smith JW, Donkor IO. Synthesis and anti-Pneumocystis carinii activity of piperidine-linked aromatic diimidazolines Bioorganic and Medicinal Chemistry Letters. 6: 2087-2090. DOI: 10.1016/0960-894X(96)00373-3  0.4
1996 Donkor IO, Queener SF, Dalton JT. Pentamidine congeners. 4. DNA binding affinity and anti-Pneumocystis carinii activity of butamidine analogues Bioorganic and Medicinal Chemistry Letters. 6: 1967-1970. DOI: 10.1016/0960-894X(96)00353-8  0.4
1996 Rosowsky A, Mota CE, Queener SF. Brominated trimetrexate analogues as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Journal of Heterocyclic Chemistry. 33: 1959-1966.  0.4
1996 Donkor IO, Devraj R, Queener SF, Barrows LR, Gangjee A. Synthesis of a Series of Diaminobenzo[f]- And Diaminobenzo[h]pyrimido[4,5-b]quinolines as 5-Deaza Tetracyclic Nonclassical Antifolates Journal of Heterocyclic Chemistry. 33: 1653-1660.  0.4
1995 Bartlett MS, Shaw M, Navaran P, Smith JW, Queener SF. Evaluation of potent inhibitors of dihydrofolate reductase in a culture model for growth of Pneumocystis carinii. Antimicrobial Agents and Chemotherapy. 39: 2436-41. PMID 8585722  0.4
1995 Rosowsky A, Mota CE, Queener SF, Waltham M, Ercikan-Abali E, Bertino JR. 2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii Journal of Medicinal Chemistry. 38: 745-752. PMID 7877140  0.4
1995 Gangjee A, Mavandadi F, Queener SF, McGuire JJ. Novel 2,4-diamino-5-substituted-pyrrolo[2,3-d]pyrimidines as classical and nonclassical antifolate inhibitors of dihydrofolate reductases Journal of Medicinal Chemistry. 38: 2158-2165. PMID 7783147  0.4
1995 Gangjee A, Vasudevan A, Queener SF, Kisliuk RL. 6-Substituted 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents Journal of Medicinal Chemistry. 38: 1778-1785. PMID 7752201  0.4
1995 Rosowsky A, Hynes JB, Queener SF. Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Antimicrobial Agents and Chemotherapy. 39: 79-86. PMID 7695334  0.4
1995 Gangjee A, Zaveri N, Kothare M, Queener SF. Nonclassical 2,4-diamino-6-(aminomethyl)-5,6,7,8-tetrahydroquinazoline antifolates: synthesis and biological activities. Journal of Medicinal Chemistry. 38: 3660-8. PMID 7658454  0.4
1995 Rosowsky A, Forsch RA, Queener SF. 2,4-Diaminopyrido[3,2-d]pyrimidine inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii Journal of Medicinal Chemistry. 38: 2615-2620. PMID 7629801  0.4
1995 Atzori C, Lu JJ, Jiang B, Bartlett MS, Orlando G, Queener SF, Smith JW, Cargnel A, Lee CH. Diagnosis of Pneumocystis carinii pneumonia in AIDS patients by using polymerase chain reactions on serum specimens. The Journal of Infectious Diseases. 172: 1623-6. PMID 7594732 DOI: 10.1093/infdis/172.6.1623  0.4
1995 Queener SF. New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carnii Journal of Medicinal Chemistry. 38: 4739-4759. PMID 7490723  0.4
1995 Rosowsky A, Mota CE, Queener SF. Synthesis and antifolate activity of 2,4-diamino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine analogues of trimetrexate and piritrexim Journal of Heterocyclic Chemistry. 32: 335-340.  0.4
1995 Gangjee A, Zaveri N, Queener SF, Kisliuk RL. Synthesis and biological activities of tetrahydroquinazoline analogs of aminopterin and methotrexate Journal of Heterocyclic Chemistry. 32: 243-247.  0.4
1994 Bartlett MS, Current WL, Orazi A, Bauer NL, Neiman RS, Queener SF, Smith JW. Comparison of corticosteroid- and L3T4+ antibody-immunosuppressed mouse models of Pneumocystis carinii pneumonia for evaluation of drugs and leukocytes. Clinical and Diagnostic Laboratory Immunology. 1: 511-6. PMID 8556494  0.4
1994 Gangjee A, Devraj R, McGuire JJ, Kisliuk RL, Queener SF, Barrows LR. Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: Synthesis and biological activities Journal of Medicinal Chemistry. 37: 1169-1176. PMID 8164259  0.4
1994 Dean RA, Ochieng W, Black J, Queener SF, Bartlett MS, Dumaual NG. Simultaneous determination of primaquine and carboxyprimaquine in plasma using high-performance liquid chromatography with electrochemical detection. Journal of Chromatography. B, Biomedical Applications. 655: 89-96. PMID 8061837 DOI: 10.1016/0378-4347(94)00087-5  0.4
1994 Bartlett MS, Queener SF, Shaw MM, Richardson JD, Smith JW. Pneumocystis carinii is resistant to imidazole antifungal agents. Antimicrobial Agents and Chemotherapy. 38: 1859-61. PMID 7986021  0.4
1994 Bartlett MS, Edlind TD, Lee CH, Dean R, Queener SF, Shaw MM, Smith JW. Albendazole inhibits Pneumocystis carinii proliferation in inoculated immunosuppressed mice. Antimicrobial Agents and Chemotherapy. 38: 1834-7. PMID 7986016  0.4
1994 Lu JJ, Bartlett MS, Shaw MM, Queener SF, Smith JW, Ortiz-Rivera M, Leibowitz MJ, Lee CH. Typing of Pneumocystis carinii strains that infect humans based on nucleotide sequence variations of internal transcribed spacers of rRNA genes. Journal of Clinical Microbiology. 32: 2904-12. PMID 7883876  0.4
1994 PAULSRUD JR, QUEENER SF. Incorporation of Fatty Acids and Amino Acids by Cultured Pneumocystis carinii Journal of Eukaryotic Microbiology. 41: 633-638. PMID 7866387 DOI: 10.1111/j.1550-7408.1994.tb01525.x  0.4
1994 Rosowsky A, Mota CE, Wright JE, Queener SF. 2,4-Diamino-5-chloroquinazoline analogues of trimetrexate and piritrexim: synthesis and antifolate activity. Journal of Medicinal Chemistry. 37: 4522-8. PMID 7799402  0.4
1993 Goheen MP, Bartlett MS, Shaw MM, Queener SF, Smith JW. Effects of 8-aminoquinolines on the ultrastructural morphology of Pneumocystis carinii. International Journal of Experimental Pathology. 74: 379-87. PMID 8398811  0.4
1993 Fishman JA, Queener SF, Roth RS, Bartlett MS. Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model. Antimicrobial Agents and Chemotherapy. 37: 1543-6. PMID 8395791  0.4
1993 Antony VB, Godbey SW, Hott JW, Queener SF. Alcohol-induced inhibition of alveolar macrophage oxidant release in vivo and in vitro Alcoholism: Clinical and Experimental Research. 17: 389-393. PMID 8387728  0.4
1993 Paulsrud JR, Queener SF, Bartlett MS, Smith JW. Total cellular fatty acid composition of cultured Pneumocystis carinii. Journal of Clinical Microbiology. 31: 1899-902. PMID 8349771  0.4
1993 Lee CH, Bauer NL, Shaw MM, Durkin MM, Bartlett MS, Queener SF, Smith JW. Proliferation of rat Pneumocystis carinii on cells sheeted on microcarrier beads in spinner flasks. Journal of Clinical Microbiology. 31: 1659-62. PMID 8315014  0.4
1993 Gangjee A, Vasudevan A, Queener SF. Bicyclic conformationally restricted analogs of nonclassical pyrido[2,3- d] pyrimidines as potential inhibitors of dihydrofolate reductases Advances in Experimental Medicine and Biology. 338: 449-452. PMID 8304156  0.4
1993 Gangjee A, Devraj R, Queener SF, Kisliuk RL. Novel 2,4-diamino-5-substituted furo[2,3-d]-pyrimidines as potential antifolates Advances in Experimental Medicine and Biology. 338: 445-448. PMID 8304155  0.4
1993 Gangjee A, Mavandadi F, Queener SF. Synthesis and biological activity of tricyclic, conformationally restricted analogs of lipophilic pyrido[2,3-d]-pyrimidine antifolates Advances in Experimental Medicine and Biology. 338: 441-444. PMID 8304154  0.4
1993 Piper JR, Johnson CA, Hosmer CA, Carter RL, Pfefferkorn ER, Borotz SE, Queener SF. Lipophilic antifolates as candidates against opportunistic infections. Advances in Experimental Medicine and Biology. 338: 429-33. PMID 8304151  0.4
1993 Queener SF, Bartlett MS, Nasr M, Smith JW. 8-aminoquinolines effective against Pneumocystis carinii in vitro and in vivo. Antimicrobial Agents and Chemotherapy. 37: 2166-72. PMID 8257140  0.4
1993 Chio LC, Queener SF. Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase Antimicrobial Agents and Chemotherapy. 37: 1914-1923. PMID 8239605  0.4
1993 Gangjee A, Shi J, Queener SF, Barrows LR, Kisliuk RL. Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents Journal of Medicinal Chemistry®. 36: 3437-3443. PMID 8230134  0.4
1993 Rosowsky A, Mota CE, Wright JE, Freisheim JH, Heusner JJ, McCormack JJ, Queener SF. 2,4-Diaminothieno[2,3-d]pyrimidine analogues of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Journal of Medicinal Chemistry. 36: 3103-3112. PMID 8230096  0.4
1992 Bartlett MS, Queener SF, Durkin MM, Shaw MA, Smith JW. Inoculated mouse model of Pneumocystis carinii infection. Diagnostic Microbiology and Infectious Disease. 15: 129-34. PMID 1572137 DOI: 10.1016/0732-8893(92)90036-S  0.4
1992 Queener SF, Dean RA, Bartlett MS, Milhous WK, Berman JD, Ellis WY, Smith JW. Efficacy of intermittent dosage of 8-aminoquinolines for therapy or prophylaxis of Pneumocystis pneumonia in rats. The Journal of Infectious Diseases. 165: 764-8. PMID 1532406 DOI: 10.1093/infdis/165.4.764  0.4
1992 Bartlett MS, Edlind TD, Durkin MM, Shaw MM, Queener SF, Smith JW. Antimicrotubule benzimidazoles inhibit in vitro growth of Pneumocystis carinii. Antimicrobial Agents and Chemotherapy. 36: 779-82. PMID 1503439  0.4
1992 Durkin MM, Bartlett MS, Queener SF, Shaw MM, Lee CH, Smith JW. An enzyme-linked immunosorbent assay for enumeration of Pneumocystis carinii in vitro and in vivo. Journal of Clinical Microbiology. 30: 3258-62. PMID 1452712  0.4
1991 Queener SF, Fujioka H, Nishiyama Y, Furukawa H, Bartlett MS, Smith JW. In vitro activities of acridone alkaloids against Pneumocystis carinii Antimicrobial Agents and Chemotherapy. 35: 377-379. PMID 2024971  0.4
1991 Bartlett MS, Queener SF, Tidwell RR, Milhous WK, Berman JD, Ellis WY, Smith JW. 8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models. Antimicrobial Agents and Chemotherapy. 35: 277-82. PMID 2024961  0.4
1991 Broughton MC, Queener SF. Pneumocystis carinii dihydrofolate reductase used to screen potential antipneumocystis drugs. Antimicrobial Agents and Chemotherapy. 35: 1348-55. PMID 1929292  0.4
1991 Queener SF. Inhibition of Pneumocystis dihydrofolate reductase by analogs of pyrimethamine, methotrexate and trimetrexate Journal of Protozoology. 38. PMID 1840146  0.4
1991 Durkin MM, Bartlett MS, Queener SF, Shaw MM, Lee CH, Smith JW. An ELISA method for quantitation of Pneumocystis carinii in culture and lung Journal of Protozoology. 38. PMID 1818173  0.4
1991 Goheen MP, Bartlett MS, Queener SF, Smith JW. The effect of primaquine on the ultrastructural morphology of Pneumocystis carinii Journal of Protozoology. 38. PMID 1818151  0.4
1991 Bartlett MS, Queener SF, Durkin MM, Shaw MM, Smith JW. Inoculated mouse model of Pneumocystis carinii pneumonia Journal of Protozoology. 38. PMID 1818136  0.4
1991 Paulsrud JR, Queener SF, Bartlett MS, Smith JW. Isolation and characterization of rat lung Pneumocystis carinii gp120 Journal of Protozoology. 38. PMID 1818123  0.4
1990 Bartlett MS, Fishman JA, Durkin MM, Queener SF, Smith JW. Pneumocystis carinii: Improved models to study efficacy of drugs for treatment or prophylaxis of Pneumocystis pneumonia in the rat (Rattus spp.) Experimental Parasitology. 70: 100-106. PMID 2295322 DOI: 10.1016/0014-4894(90)90089-U  0.4
1989 Rosowsky A, Freisheim JH, Hynes JB, Queener SF, Bartlett M, Smith JW, Lazarus H, Modest EJ. Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin Biochemical Pharmacology. 38: 2677-2684. PMID 2788420 DOI: 10.1016/0006-2952(89)90554-6  0.4
1989 BARLETT MS, FISHMAN JA, DURKIN MM, QUEENER SF, SMITH JW. An Improved Rat Model to Study Efficacy of Drugs for Treatment or Prophylaxis of Pneumocystis carinii Pneumonia The Journal of Protozoology. 36: 77S-78S. PMID 2785207 DOI: 10.1111/j.1550-7408.1989.tb02712.x  0.4
1989 Richardson JD, Queener SF, Bartlett M, Smith J. Binary fission of Pneumocystis carinii trophozoites grown in vitro. The Journal of Protozoology. 36: 27S-29S. PMID 2785186 DOI: 10.1111/j.1550-7408.1989.tb02678.x  0.4
1989 DL'RKIN MM, BARTLETT MS, QUEENER SF, SHAW MM, SMITH JW. A Culture Method Allowing Production of Relatively Pure Pneumocystis carinii Trophozoites The Journal of Protozoology. 36: 31S-32S. PMID 2468767 DOI: 10.1111/j.1550-7408.1989.tb02681.x  0.4
1988 Queener SF, Bartlett MS, Richardson JD, Durkin MM, Jay MA, Smith JW. Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo. Antimicrobial Agents and Chemotherapy. 32: 807-13. PMID 3261959  0.4
1988 Bartlett MS, Fishman JA, Queener SF, Durkin MM, Jay MA, Smith JW. New rat model of Pneumocystis carinii infection Journal of Clinical Microbiology. 26: 1100-1102. PMID 3260241  0.4
1987 Smith JW, Bartlett MS, Queener SF, Durkin MM, Jay MA, Hull MT, Klein RS, Marr JJ. Pneumocystis carinii pneumonia therapy with 9-deazainosine in rats. Diagnostic Microbiology and Infectious Disease. 7: 113-8. PMID 3498606 DOI: 10.1016/0732-8893(87)90028-9  0.4
1987 Bartlett MS, Durkin MM, Jay MA, Queener SF, Smith JW. Sources of rats free of latent Pneumocystis carinii Journal of Clinical Microbiology. 25: 1794-1795. PMID 2958497  0.4
1987 Bartlett MS, Queener SF, Jay MA, Durkin MM, Smith JW. Improved rat model for studying Pneumocystis carinii pneumonia Journal of Clinical Microbiology. 25: 480-484. PMID 2952669  0.4
1987 Queener SF, Bartlett MS, Jay MA, Durkin MM, Smith JW. Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection Antimicrobial Agents and Chemotherapy. 31: 1323-1327. PMID 2445281  0.4
1986 Myers MJ, Heim MC, Hirsch KS, Queener SF, Petersen BH. Translocatable estrogen receptors in rat splenocytes Life Sciences. 39: 313-320. PMID 3736328 DOI: 10.1016/0024-3205(86)90649-1  0.4
1986 Bartlett MS, Marr JJ, Queener SF, Klein RS, Smith JW. Activity of inosine analogs against Pneumocystis carinii in culture. Antimicrobial Agents and Chemotherapy. 30: 181-3. PMID 3489438  0.4
1985 Clark DL, Queener SF. Effects of diabetes mellitus on renal fatty acid activation and desaturation Biochemical Pharmacology. 34: 4305-4310. PMID 4074391 DOI: 10.1016/0006-2952(85)90289-8  0.4
1984 Clark DL, Queener SF. Renal lipid desaturation in diabetes mellitus Federation Proceedings. 43.  0.4
1983 Queener SF, Luft FC, Hamel FG. Effect of gentamicin treatment on adenylate cyclase and Na+,K+-ATPase activities in renal tissues of rats Antimicrobial Agents and Chemotherapy. 24: 815-818. PMID 6318658 DOI: 10.1128/AAC.24.5.815  0.4
1983 Clark DL, Hamel FG, Queener SF. Changes in renal phospholipid fatty acids in diabetes mellitus: Correlation with changes in adenylate cyclase activity Lipids. 18: 696-705. PMID 6318007 DOI: 10.1007/BF02534536  0.4
1982 Hamel FG, Queener SF. Solubilization of hormone-responsive adenylate cyclase from human renal cortex Biochemical and Biophysical Research Communications. 108: 567-575. PMID 7150307 DOI: 10.1016/0006-291X(82)90866-X  0.4
1982 Hollingsead PS, Queener SF, Besch HR, Willis LR. ±3H-carazolol binding to rabbit renal cortical membranes Clinical Research. 30.  0.4
1980 Fricke RF, Queener SF, Clark CM. Cardiac adenylate cyclase: Kinetics of synergistic activation by guanosine-5′-triphosphate (GTP) and glucagon Journal of Molecular and Cellular Cardiology. 12: 595-608. PMID 7452736 DOI: 10.1016/0022-2828(80)90017-6  0.4
1980 Queener SF, Bell NH, Larson SM, Henry DP, Slatopolsky E. Comparison of the regulation of calcitonin in serum of old and young Buffalo rats Journal of Endocrinology. 87: 73-80. PMID 7430917 DOI: 10.1677/joe.0.0870073  0.4
1979 Wiske PS, Epstein S, Bell NH, Queener SF, Edmondson J, Johnston CC. Increases in immunoreactive parathyroid hormone with age. The New England Journal of Medicine. 300: 1419-21. PMID 440391 DOI: 10.1056/NEJM197906213002506  0.4
1978 Queener SF, Fleming JW, Bell NH. Analysis of sodium fluoride enhancement of calcitonin stimulation of renal cortical adenylate cyclase. The Journal of Biological Chemistry. 253: 9033-40. PMID 721827  0.4
1978 Brooks MH, Bell NH, Love L, Stern PH, Orfei E, Queener SF, Hamstra AJ, DeLuca HF. Vitamin-D-dependent rickets type II. Resistance of target organs to 1,25-dihydroxyvitamin D New England Journal of Medicine. 298: 996-999. PMID 205789 DOI: 10.1056/NEJM197805042981804  0.4
1977 Willis LR, Queener SF. Pentobarbital sleeping time and waking blood levels in spontaneously hypertensive rats. Canadian Journal of Physiology and Pharmacology. 55: 1205-7. PMID 922589  0.4
1977 Sinha TK, Allen DO, Queener SF, Bell NH, Larson S, McClintock R. Effects of acetazolamide on the renal excretion of phosphate in hypoparathyroidism and pseudohypoparathyroidism. The Journal of Laboratory and Clinical Medicine. 89: 1188-97. PMID 194004  0.4
1976 Bell NH, Queener SF. Clinical implications of abnormalities in the metabolism of vitamin D Journal of Chronic Diseases. 29: 743-746. PMID 1010868 DOI: 10.1016/0021-9681(76)90048-5  0.4
1976 Bell NH, Queener SF. A Radioimmunoassay for Serum Calcitonin in the Rat (39430) Proceedings of the Society For Experimental Biology and Medicine. 152: 516-519. PMID 967879 DOI: 10.3181/00379727-152-39430  0.4
1976 Thajchayapong P, Queener SF, McClintock R, Allen DO, Bell NH. Demonstration that cyclic adenosine 3',5'-monophosphate mediates the lipolytic action of parathyroid hormone. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 8: 190-5. PMID 181304 DOI: 10.1055/s-0028-1093658  0.4
1976 Sinha TK, Thajchayapong P, Queener SF, Allen DO, Bell NH. On the lipolytic action of parathyroid hormone in man. Metabolism: Clinical and Experimental. 25: 251-60. PMID 175239 DOI: 10.1016/0022-2836(76)90243-6  0.4
1976 Sinha TK, Queener SF, Bell NH. Acquired resistance to parathyroid hormone Acta Endocrinologica. 83: 321-328. PMID 61689 DOI: 10.1530/acta.0.0830321  0.4
1976 Queener SF, Bell NH. Treatment of experimental vitamin D3 intoxication in the rat with cholestyramine Clinical Research. 24.  0.4
1976 Fleming JW, Queener SF, Bell NH. Synergistic activation of renal cortical adenylate cyclase by sodium fluoride and calcitonin Federation Proceedings. 35.  0.4
1975 Queener SF, Bell NH. Calcitonin: A general survey Metabolism. 24: 555-567. PMID 1167927 DOI: 10.1016/0026-0495(75)90080-3  0.4
1975 Queener SF, Fleming JW, Bell NH. Solubilization of calcitonin-responsive renal cortical adenylate cyclase. The Journal of Biological Chemistry. 250: 7586-92. PMID 170264  0.4
1975 Sinha TK, Thajchayapong P, Queener SF. On the lipolytic action of parathyroid hormone (PTH) in man Clinical Research. 23.  0.4
1974 Fleming JW, Queener SF, Bell NH. Binding and degradation of radioiodinated calcitonin by solubilized reparation containing calcitonin responsive adenylate cyclase Clinical Research. 22.  0.4
1972 Weber G, Ferdinandus JA, Queener SF, Dunaway GA, Trailan LJP. Metabolic Imbalance in Carbohydrate, Pyrimidine and Ornithine Utilization Advances in Enzyme Regulation. 10: 39-62. PMID 4653827 DOI: 10.1016/0065-2571(72)90005-2  0.4
1972 Morris HP, Weber G, Queener SF. Imbalance in Ornithine Metabolism in Hepatomas of Different Growth Rates as Expressed in Behavior of L-Ornithine Carbamyl Transferase Activity Cancer Research. 32: 1933-1940. PMID 4345042  0.4
1971 Queener SF, Morris HP, Weber G. Dihydrouracil Dehydrogenase Activity in Normal, Differentiating, and Regenerating Liver and in Hepatomas Cancer Research. 31: 1004-1009. PMID 4397791  0.4
1971 Weber G, Queener SF, Ferdinandus JA. Control of gene expression in carbohydrate, pyrimidine and DNA metabolism Advances in Enzyme Regulation. 9: 63-95. PMID 4329198 DOI: 10.1016/S0065-2571(71)80038-9  0.4
1970 Queener SF, Gunsalus IC. Anthranilate synthase enzyme system and complementation in Pseudomonas species. Proceedings of the National Academy of Sciences of the United States of America. 67: 1225-32. PMID 5274451  0.4
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