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John M. Pezzuto - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center 
Area:
Pharmacology, Microbiology Biology, Public Health, Pathology
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Year Citation  Score
2016 Guan Y, Wang D, Tan GT, Van Hung N, Cuong NM, Pezzuto JM, Fong HH, Soejarto DD, Zhang H. Litsea Species as Potential Antiviral Plant Sources. The American Journal of Chinese Medicine. 44: 275-90. PMID 27080941 DOI: 10.1142/S0192415X16500166  0.32
2015 Jabeen F, Panda SS, Kondratyuk TP, Park EJ, Pezzuto JM, Ihsan-Ul-Haq, Hall CD, Katritzky AR. Synthesis, molecular docking and anticancer studies of peptides and iso-peptides. Bioorganic & Medicinal Chemistry Letters. 25: 2980-4. PMID 26048799 DOI: 10.1016/j.bmcl.2015.05.020  0.44
2015 Park EJ, Pezzuto JM. The pharmacology of resveratrol in animals and humans. Biochimica Et Biophysica Acta. 1852: 1071-113. PMID 25652123 DOI: 10.1016/j.bbadis.2015.01.014  0.44
2014 Parrish SM, Yoshida WY, Kondratyuk TP, Park EJ, Pezzuto JM, Kelly M, Williams PG. Spongiapyridine and related spongians isolated from an Indonesian Spongia sp. Journal of Natural Products. 77: 1644-9. PMID 24992702 DOI: 10.1021/np500256w  0.44
2014 García ME, Nicotra VE, Oberti JC, Ríos-Luci C, León LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padrón JM, Hueso-Falcón I, Estévez-Braun A. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives. European Journal of Medicinal Chemistry. 82: 68-81. PMID 24878636 DOI: 10.1016/j.ejmech.2014.05.045  0.44
2014 Chai X, Youn UJ, Sun D, Dai J, Williams P, Kondratyuk TP, Borris RP, Davies J, Villanueva IG, Pezzuto JM, Chang LC. Herbicidin congeners, undecose nucleosides from an organic extract of Streptomyces sp. L-9-10. Journal of Natural Products. 77: 227-33. PMID 24533857 DOI: 10.1021/np4006635  0.44
2014 Pan W, Liu K, Guan Y, Tan GT, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HHS, Zhang H. Bioactive compounds from Vitex leptobotrys Journal of Natural Products. 77: 663-667. PMID 24404757 DOI: 10.1021/np400779v  0.44
2014 Park EJ, Shen L, Sun D, Pezzuto JM. Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Natural Products. 77: 527-35. PMID 24299616 DOI: 10.1021/np400800h  0.44
2014 Endringer DC, Taveira FSN, Kondratyuk TP, Pezzuto JM, Bragaa FC. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium Brazilian Journal of Pharmacognosy. 24: 408-412. DOI: 10.1016/j.bjp.2014.08.002  0.44
2013 Pezzuto JM, Kondratyuk TP, Ogas T. Resveratrol derivatives: a patent review (2009 - 2012). Expert Opinion On Therapeutic Patents. 23: 1529-46. PMID 24032623 DOI: 10.1517/13543776.2013.834888  0.44
2013 Pansanit A, Park EJ, Kondratyuk TP, Pezzuto JM, Lirdprapamongkol K, Kittakoop P. Vermelhotin, an anti-inflammatory agent, suppresses nitric oxide production in RAW 264.7 cells via p38 inhibition. Journal of Natural Products. 76: 1824-7. PMID 24016057 DOI: 10.1021/np400565e  0.44
2013 Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. European Journal of Medicinal Chemistry. 68: 412-21. PMID 23994869 DOI: 10.1016/j.ejmech.2013.07.052  0.44
2013 Ogas T, Kondratyuk TP, Pezzuto JM. Resveratrol analogs: promising chemopreventive agents. Annals of the New York Academy of Sciences. 1290: 21-9. PMID 23855462 DOI: 10.1111/nyas.12196  0.44
2013 Carlson S, Marler L, Nam SJ, Santarsiero BD, Pezzuto JM, Murphy BT. Potential chemopreventive activity of a new macrolide antibiotic from a marine-derived Micromonospora sp. Marine Drugs. 11: 1152-61. PMID 23552877 DOI: 10.3390/md11041152  0.44
2013 Pezzuto JM, Patel P. Retraction of: Li CM, Jiang WL, Zhu HB, Hou J. Antifibrotic effects of protocatechuic aldehyde on experimental liver fibrosis. Pharmaceutical Biology. 51: 675. PMID 23510404 DOI: 10.3109/13880209.2013.782159  0.44
2013 Conda-Sheridan M, Park EJ, Beck DE, Reddy PV, Nguyen TX, Hu B, Chen L, White JJ, van Breemen RB, Pezzuto JM, Cushman M. Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential. Journal of Medicinal Chemistry. 56: 2581-605. PMID 23472886 DOI: 10.1021/jm400026k  0.44
2013 Park EJ, Pezzuto JM. Antioxidant marine products in cancer chemoprevention. Antioxidants & Redox Signaling. 19: 115-38. PMID 23397932 DOI: 10.1089/ars.2013.5235  0.44
2013 Ihsan-ul-Haq, Youn UJ, Chai X, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Mirza B, Pezzuto JM, Chang LC. Biologically active withanolides from Withania coagulans. Journal of Natural Products. 76: 22-8. PMID 23316950 DOI: 10.1021/np300534x  0.44
2013 Haq IU, Mirza B, Kondratyuk TP, Park EJ, Burns BE, Marler LE, Pezzuto JM. Preliminary evaluation for cancer chemopreventive and cytotoxic potential of naturally growing ethnobotanically selected plants of Pakistan Pharmaceutical Biology. 51: 316-328. PMID 23137214 DOI: 10.3109/13880209.2012.728612  0.44
2013 Suh N, Pezzuto JM. Preface Topics in Current Chemistry. 329. DOI: 10.1007/978-3-642-34575-3  0.44
2012 Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1). Bioorganic & Medicinal Chemistry. 20: 7030-9. PMID 23142320 DOI: 10.1016/j.bmc.2012.10.006  0.44
2012 Yu X, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors. Organic & Biomolecular Chemistry. 10: 8835-47. PMID 23044819 DOI: 10.1039/c2ob26456k  0.44
2012 Archer CR, Groll M, Stein ML, Schellenberg B, Clerc J, Kaiser M, Kondratyuk TP, Pezzuto JM, Dudler R, Bachmann AS. Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells. Biochemistry. 51: 6880-8. PMID 22870914 DOI: 10.1021/bi300841r  0.44
2012 Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Tanamatayarat P, Wongwiwatthananukit S, Toyama O, Songsak T, Pezzuto JM, Chang LC. Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorganic & Medicinal Chemistry Letters. 22: 5559-62. PMID 22850207 DOI: 10.1016/j.bmcl.2012.07.010  0.44
2012 Sun D, Hurdle JG, Lee R, Lee R, Cushman M, Pezzuto JM. Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead. Chemmedchem. 7: 1541-5. PMID 22847956 DOI: 10.1002/cmdc.201200253  0.44
2012 Park EJ, Pezzuto JM, Jang KH, Nam SJ, Bucarey SA, Fenical W. Suppression of nitric oxide synthase by thienodolin in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Natural Product Communications. 7: 789-94. PMID 22816309  0.44
2012 Luqman S, Meena A, Singh P, Kondratyuk TP, Marler LE, Pezzuto JM, Negi AS. Neoflavonoids and tetrahydroquinolones as possible cancer chemopreventive agents. Chemical Biology & Drug Design. 80: 616-24. PMID 22726671 DOI: 10.1111/j.1747-0285.2012.01439.x  0.44
2012 Chen L, Conda-Sheridan M, Reddy PV, Morrell A, Park EJ, Kondratyuk TP, Pezzuto JM, van Breemen RB, Cushman M. Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. Journal of Medicinal Chemistry. 55: 5965-81. PMID 22712432 DOI: 10.1021/jm3006806  0.44
2012 Kondratyuk TP, Park EJ, Yu R, van Breemen RB, Asolkar RN, Murphy BT, Fenical W, Pezzuto JM. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Marine Drugs. 10: 451-64. PMID 22412812 DOI: 10.3390/md10020451  0.44
2012 Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol. Bioorganic & Medicinal Chemistry. 20: 2427-34. PMID 22386564 DOI: 10.1016/j.bmc.2012.01.047  0.44
2012 Park EJ, Pezzuto JM. Flavonoids in cancer prevention. Anti-Cancer Agents in Medicinal Chemistry. 12: 836-51. PMID 22292763 DOI: 10.2174/187152012802650075  0.44
2012 Suh N, Pezzuto JM. Strawberry fields forever? Cancer Prevention Research (Philadelphia, Pa.). 5: 30-3. PMID 22219164 DOI: 10.1158/1940-6207.CAPR-11-0534  0.44
2012 Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Xuan LT, Hiep NT, Hung NV, Loc PK, Dac LX, Bich TQ, Cuong NM, Ly HM, Zhang HJ, ... ... Pezzuto JM, et al. Ethnobotanical approach versus random approach in the search for new bioactive compounds: support of a hypothesis. Pharmaceutical Biology. 50: 30-41. PMID 22196581 DOI: 10.3109/13880209.2011.634424  0.44
2012 Park EJ, Kiselev E, Conda-Sheridan M, Cushman M, Pezzuto JM. Induction of apoptosis by 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline via modulation of MAPKs (p38 and c-Jun N-terminal kinase) and c-Myc in HL-60 human leukemia cells. Journal of Natural Products. 75: 378-84. PMID 22148260 DOI: 10.1021/np200791j  0.44
2012 Soejarto DD, Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Zhang HJ, Franzblau SG, Tan GT, Pezzuto JM, Riley MC, Elkington BG, Waller DP. An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development. Pharmaceutical Biology. 50: 42-60. PMID 22136442 DOI: 10.3109/13880209.2011.619700  0.44
2012 Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. Bioorganic & Medicinal Chemistry. 20: 510-20. PMID 22115839 DOI: 10.1016/j.bmc.2011.09.031  0.44
2012 Lewandowski C, Pezzuto JM. Pharmaceutical Biology: a retrospective. Pharmaceutical Biology. 50: 1-5. PMID 22014232 DOI: 10.3109/13880209.2011.621961  0.44
2011 Park EJ, Cheenpracha S, Chang LC, Pezzuto JM. Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated RAW 264.7 cells. Phytochemistry Letters. 4: 426-431. PMID 22180763 DOI: 10.1016/j.phytol.2011.07.009  0.44
2011 Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorganic & Medicinal Chemistry. 19: 6182-95. PMID 21978950 DOI: 10.1016/j.bmc.2011.09.020  0.44
2011 Park EJ, Cheenpracha S, Chang LC, Kondratyuk TP, Pezzuto JM. Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera. Nutrition and Cancer. 63: 971-82. PMID 21774591 DOI: 10.1080/01635581.2011.589960  0.44
2011 Kondratyuk TP, Park EJ, Marler LE, Ahn S, Yuan Y, Choi Y, Yu R, van Breemen RB, Sun B, Hoshino J, Cushman M, Jermihov KC, Mesecar AD, Grubbs CJ, Pezzuto JM. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Molecular Nutrition & Food Research. 55: 1249-65. PMID 21714126 DOI: 10.1002/mnfr.201100122  0.44
2011 Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, Das DK, Delmas D, Gottfried C, Lin HY, Ma QY, Mukhopadhyay P, Nalini N, Pezzuto JM, Richard T, et al. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. Plos One. 6: e19881. PMID 21698226 DOI: 10.1371/journal.pone.0019881  0.44
2011 Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Suppression of tumor necrosis factor-α-induced nuclear factor κB activation and aromatase activity by capsaicin and its analog capsazepine. Journal of Medicinal Food. 14: 1344-51. PMID 21663483 DOI: 10.1089/jmf.2010.0236  0.44
2011 Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM. Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 592-607. PMID 21464033 DOI: 10.1158/1940-6207.CAPR-10-0004  0.44
2011 Zou J, Pan L, Li Q, Zhao J, Pu J, Yao P, Gong N, Lu Y, Kondratyuk TP, Pezzuto JM, Fong HH, Zhang H, Sun H. Rubesanolides A and B: diterpenoids from Isodon rubescens. Organic Letters. 13: 1406-9. PMID 21332131 DOI: 10.1021/ol200086k  0.44
2011 Pezzuto JM. The phenomenon of resveratrol: redefining the virtues of promiscuity. Annals of the New York Academy of Sciences. 1215: 123-30. PMID 21261650 DOI: 10.1111/j.1749-6632.2010.05849.x  0.44
2011 Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, et al. Bioactive compounds from the fern Lepisorus contortus. Journal of Natural Products. 74: 129-36. PMID 21261296 DOI: 10.1021/np100373f  0.44
2011 Choi Y, Jermihov K, Nam SJ, Sturdy M, Maloney K, Qiu X, Chadwick LR, Main M, Chen SN, Mesecar AD, Farnsworth NR, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Analytical Chemistry. 83: 1048-52. PMID 21192729 DOI: 10.1021/ac1028424  0.44
2011 Guilford JM, Pezzuto JM. Wine and health: A review American Journal of Enology and Viticulture. 62: 471-486. DOI: 10.5344/ajev.2011.11013  0.44
2010 Marler L, Conda-Sheridan M, Cinelli MA, Morrell AE, Cushman M, Chen L, Huang K, Van Breemen R, Pezzuto JM. Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives. Anticancer Research. 30: 4873-82. PMID 21187465  0.44
2010 Conda-Sheridan M, Marler L, Park EJ, Kondratyuk TP, Jermihov K, Mesecar AD, Pezzuto JM, Asolkar RN, Fenical W, Cushman M. Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284. Journal of Medicinal Chemistry. 53: 8688-99. PMID 21105712 DOI: 10.1021/jm1011066  0.44
2010 Gullett NP, Ruhul Amin AR, Bayraktar S, Pezzuto JM, Shin DM, Khuri FR, Aggarwal BB, Surh YJ, Kucuk O. Cancer prevention with natural compounds. Seminars in Oncology. 37: 258-81. PMID 20709209 DOI: 10.1053/j.seminoncol.2010.06.014  0.44
2010 Cheenpracha S, Park EJ, Yoshida WY, Barit C, Wall M, Pezzuto JM, Chang LC. Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits. Bioorganic & Medicinal Chemistry. 18: 6598-602. PMID 20685125 DOI: 10.1016/j.bmc.2010.03.057  0.44
2010 Luqman S, Pezzuto JM. NFkappaB: a promising target for natural products in cancer chemoprevention. Phytotherapy Research : Ptr. 24: 949-63. PMID 20577970 DOI: 10.1002/ptr.3171  0.44
2010 Sun B, Hoshino J, Jermihov K, Marler L, Pezzuto JM, Mesecar AD, Cushman M. Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer. Bioorganic & Medicinal Chemistry. 18: 5352-66. PMID 20558073 DOI: 10.1016/j.bmc.2010.05.042  0.44
2010 Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. Journal of Medicinal Chemistry. 53: 5033-43. PMID 20527891 DOI: 10.1021/jm100274c  0.44
2010 Nam SJ, Gaudêncio SP, Kauffman CA, Jensen PR, Kondratyuk TP, Marler LE, Pezzuto JM, Fenical W. Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis. Journal of Natural Products. 73: 1080-6. PMID 20481500 DOI: 10.1021/np100087c  0.44
2010 Calamini B, Ratia K, Malkowski MG, Cuendet M, Pezzuto JM, Santarsiero BD, Mesecar AD. Pleiotropic mechanisms facilitated by resveratrol and its metabolites. The Biochemical Journal. 429: 273-82. PMID 20450491 DOI: 10.1042/BJ20091857  0.44
2010 Cheenpracha S, Park EJ, Rostama B, Pezzuto JM, Chang LC. Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells by the norsesterterpene peroxide, epimuqubilin A. Marine Drugs. 8: 429-37. PMID 20411107 DOI: 10.3390/md8030429  0.44
2010 Morais MC, Luqman S, Kondratyuk TP, Petronio MS, Regasini LO, Silva DH, Bolzani VS, Soares CP, Pezzuto JM. Suppression of TNF-α induced NFκB activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Natural Product Research. 24: 1758-65. PMID 20408045 DOI: 10.1080/14786410903335232  0.44
2010 Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, et al. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 71: 641-7. PMID 20100622 DOI: 10.1016/j.phytochem.2010.01.002  0.44
2010 Cuendet M, Guo J, Luo Y, Chen S, Oteham CP, Moon RC, van Breemen RB, Marler LE, Pezzuto JM. Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prevention Research (Philadelphia, Pa.). 3: 221-32. PMID 20068129 DOI: 10.1158/1940-6207.CAPR-09-0049  0.44
2010 Endringer DC, Valadares YM, Campana PR, Campos JJ, Guimarães KG, Pezzuto JM, Braga FC. Evaluation of Brazilian plants on cancer chemoprevention targets in vitro. Phytotherapy Research : Ptr. 24: 928-33. PMID 19957245 DOI: 10.1002/ptr.3050  0.44
2009 Balunas MJ, Su B, Riswan S, Fong HH, Brueggemeier RW, Pezzuto JM, Kinghorn AD. Isolation and Characterization of Aromatase Inhibitors from Brassaiopsis glomerulata (Araliaceae). Phytochemistry Letters. 2: 29-33. PMID 20161072 DOI: 10.1016/j.phytol.2008.10.009  0.44
2009 Schupp PJ, Kohlert-Schupp C, Whitefield S, Engemann A, Rohde S, Hemscheidt T, Pezzuto JM, Kondratyuk TP, Park EJ, Marler L, Rostama B, Wright AD. Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam. Natural Product Communications. 4: 1717-28. PMID 20120114  0.44
2009 Pezzuto JM, Venkatasubramanian V, Hamad M, Morris KR. Unraveling the relationship between grapes and health. The Journal of Nutrition. 139: 1783S-7S. PMID 19625701 DOI: 10.3945/jn.109.107458  0.44
2009 Endringer DC, Pezzuto JM, Braga FC. NF-kappaB inhibitory activity of cyclitols isolated from Hancornia speciosa. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 16: 1064-9. PMID 19423310 DOI: 10.1016/j.phymed.2009.03.022  0.44
2009 Deng Y, Balunas MJ, Kim JA, Lantvit DD, Chin YW, Chai H, Sugiarso S, Kardono LB, Fong HH, Pezzuto JM, Swanson SM, de Blanco EJ, Kinghorn AD. Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. Journal of Natural Products. 72: 1165-9. PMID 19422206 DOI: 10.1021/np9001724  0.44
2009 Maiti A, Reddy PV, Sturdy M, Marler L, Pegan SD, Mesecar AD, Pezzuto JM, Cushman M. Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities. Journal of Medicinal Chemistry. 52: 1873-84. PMID 19265439 DOI: 10.1021/jm801335z  0.44
2009 Yao G, Kondratyuk TP, Tan GT, Pezzuto JM, Chang LC. Bioactive sulfated sesterterpene alkaloids and sesterterpene sulfates from the marine sponge Fasciospongia sp. Journal of Natural Products. 72: 319-23. PMID 19178162 DOI: 10.1021/np8005343  0.44
2009 Mi Q, Pezzuto JM, Farnsworth NR, Wani MC, Kinghorn AD, Swanson SM. Use of the in vivo hollow fiber assay in natural products anticancer drug discovery. Journal of Natural Products. 72: 573-80. PMID 19161316 DOI: 10.1021/np800767a  0.44
2009 Asolkar RN, Freel KC, Jensen PR, Fenical W, Kondratyuk TP, Park EJ, Pezzuto JM. Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. Journal of Natural Products. 72: 396-402. PMID 19117399 DOI: 10.1021/np800617a  0.44
2009 Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorganic & Medicinal Chemistry. 17: 1044-54. PMID 18487053 DOI: 10.1016/j.bmc.2008.04.031  0.44
2009 Ghufran MA, Qureshi RA, Batool A, Kondratyuk TP, Guilford JM, Marler LE, Chang LC, Pezzuto JM. Evaluation of selected indigenous medicinal plants from the western Himalayas for cytotoxicity and as potential cancer chemopreventive agents Pharmaceutical Biology. 47: 533-538. DOI: 10.1080/13880200902873847  0.44
2008 Cuendet M, Oteham CP, Maiti A, Craig BA, Cushman M, Moon RC, Pezzuto JM. Zapotin prevents mouse skin tumorigenesis during the stages of initiation and promotion. Anticancer Research. 28: 3705-9. PMID 19189653  0.44
2008 Guilford JM, Pezzuto JM. Natural products as inhibitors of carcinogenesis. Expert Opinion On Investigational Drugs. 17: 1341-52. PMID 18694367 DOI: 10.1517/13543784.17.9.1341  0.44
2008 Pezzuto JM. Grapes and human health: a perspective. Journal of Agricultural and Food Chemistry. 56: 6777-84. PMID 18662007 DOI: 10.1021/jf800898p  0.44
2008 Guo J, Liu A, Cao H, Luo Y, Pezzuto JM, van Breemen RB. Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2104-12. PMID 18653743 DOI: 10.1124/dmd.108.021857  0.44
2008 Francy-Guilford J, Pezzuto JM. Mechanisms of cancer chemopreventive agents: a perspective. Planta Medica. 74: 1644-50. PMID 18537076 DOI: 10.1055/s-2008-1074553  0.44
2008 Endringer DC, Guimarães KG, Kondratyuk TP, Pezzuto JM, Braga FC. Selective inhibition of aromatase by a dihydroisocoumarin from Xyris pterygoblephara. Journal of Natural Products. 71: 1082-4. PMID 18462007 DOI: 10.1021/np800098f  0.44
2008 Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 461-8. PMID 18006650 DOI: 10.1124/dmd.107.018721  0.44
2008 Pezzuto JM. Resveratrol as an inhibitor of carcinogenesis Pharmaceutical Biology. 46: 443-573. DOI: 10.1080/13880200802116610  0.44
2008 Topcu G, Turkmen Z, Schilling JK, Kingston DGI, Pezzuto JM, Ulubelen A. Cytotoxic activity of some Anatolian Salvia extracts and isolated abietane diterpenoids Pharmaceutical Biology. 46: 180-184. DOI: 10.1080/13880200701735411  0.44
2008 Cuendet M, Oteham CP, Moon RC, Keller WJ, Peaden PA, Pezzuto JM. Dietary administration of Asimina triloba (paw paw) extract increases tumor latency in N-methyl-N-nitrosourea-treated rats Pharmaceutical Biology. 46: 3-7. DOI: 10.1080/13880200701729497  0.44
2007 Endringer DC, Pezzuto JM, Soares CM, Braga FC. L-(+)-Bornesitol. Acta Crystallographica. Section E, Structure Reports Online. 63: o1067-o1068. PMID 19011691 DOI: 10.1107/S1600536806037019  0.44
2007 Liu D, Guo J, Luo Y, Broderick DJ, Schimerlik MI, Pezzuto JM, van Breemen RB. Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry. Analytical Chemistry. 79: 9398-402. PMID 17997524 DOI: 10.1021/ac701701k  0.44
2007 Murillo G, Hirschelman WH, Ito A, Moriarty RM, Kinghorn AD, Pezzuto JM, Mehta RG. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutrition and Cancer. 57: 28-37. PMID 17516860 DOI: 10.1080/01635580701268097  0.44
2007 Maiti A, Cuendet M, Croy VL, Endringer DC, Pezzuto JM, Cushman M. Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer. Journal of Medicinal Chemistry. 50: 2799-806. PMID 17511439 DOI: 10.1021/jm070109i  0.44
2007 Williams PG, Asolkar RN, Kondratyuk T, Pezzuto JM, Jensen PR, Fenical W. Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola. Journal of Natural Products. 70: 83-8. PMID 17253854 DOI: 10.1021/np0604580  0.44
2007 Maiti A, Cuendet M, Kondratyuk T, Croy VL, Pezzuto JM, Cushman M. Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. Journal of Medicinal Chemistry. 50: 350-5. PMID 17228877 DOI: 10.1021/jm060915  0.44
2007 Jutiviboonsuk A, Zhang HJ, Kondratyuk TP, Herunsalee A, Chaukul W, Pezzuto JM, Fong HHS, Bunyapraphatsara N. Isolation and characterization of cancer chemopreventive compounds from Barringtonia maunwongyathiae Pharmaceutical Biology. 45: 185-194. DOI: 10.1080/13880200701213062  0.44
2007 Cuendet M, Pezzuto JM. Antitumor Alkaloids in Clinical Use or in Clinical Trials Modern Alkaloids: Structure, Isolation, Synthesis and Biology. 25-52. DOI: 10.1002/9783527621071.ch2  0.44
2006 Cuendet M, Mesecar AD, DeWitt DL, Pezzuto JM. An ELISA method to measure inhibition of the COX enzymes. Nature Protocols. 1: 1915-21. PMID 17487176 DOI: 10.1038/nprot.2006.308  0.44
2006 Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. The Febs Journal. 273: 5714-23. PMID 17212786 DOI: 10.1111/j.1742-4658.2006.05560.x  0.44
2006 Thole JM, Kraft TF, Sueiro LA, Kang YH, Gills JJ, Cuendet M, Pezzuto JM, Seigler DS, Lila MA. A comparative evaluation of the anticancer properties of European and American elderberry fruits. Journal of Medicinal Food. 9: 498-504. PMID 17201636 DOI: 10.1089/jmf.2006.9.498  0.44
2006 Balunas MJ, Jones WP, Chin YW, Mi Q, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Chai HB, Kinghorn AD. Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chemistry & Biodiversity. 3: 897-915. PMID 17193321 DOI: 10.1002/cbdv.200690092  0.44
2006 Wright AD, de Nys R, Angerhofer CK, Pezzuto JM, Gurrath M. Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products. Journal of Natural Products. 69: 1180-7. PMID 16933872 DOI: 10.1021/np050510c  0.44
2006 He ZD, Ma CY, Tan GT, Sydara K, Tamez P, Southavong B, Bouamanivong S, Soejarto DD, Pezzuto JM, Fong HH, Zhang HJ. Rourinoside and rouremin, antimalarial constituents from Rourea minor. Phytochemistry. 67: 1378-84. PMID 16762381 DOI: 10.1016/j.phytochem.2006.04.012  0.44
2006 Carcache-Blanco EJ, Cuendet M, Park EJ, Su BN, Rivero-Cruz JF, Farnsworth NR, Pezzuto JM, Douglas Kinghorn A. Potential cancer chemopreventive agents from Arbutus unedo. Natural Product Research. 20: 327-34. PMID 16644527 DOI: 10.1080/14786410500161205  0.44
2006 Soejarto DD, Zhang HJ, Fong HH, Tan GT, Ma CY, Gyllenhaal C, Riley MC, Kadushin MR, Franzblau SG, Bich TQ, Cuong NM, Hiep NT, Loc PK, Xuan le T, Hai NV, ... ... Pezzuto JM, et al. "Studies on biodiversity of Vietnam and Laos" 1998-2005: examining the impact. Journal of Natural Products. 69: 473-81. PMID 16562860 DOI: 10.1021/np058107t  0.44
2006 Cuendet M, Oteham CP, Moon RC, Pezzuto JM. Quinone reductase induction as a biomarker for cancer chemoprevention. Journal of Natural Products. 69: 460-3. PMID 16562858 DOI: 10.1021/np050362q  0.44
2006 Homhual S, Bunyapraphatsara N, Kondratyuk T, Herunsalee A, Chaukul W, Pezzuto JM, Fong HHS, Zhang HJ. Bioactive dammarane triterpenes from the mangrove Plant Bruguiera gymnorrhiza Journal of Natural Products. 69: 421-424. PMID 16562850 DOI: 10.1021/np058112x  0.44
2006 Fang L, Ito A, Chai HB, Mi Q, Jones WP, Madulid DR, Oliveros MB, Gao Q, Orjala J, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Kinghorn AD. Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines. Journal of Natural Products. 69: 332-7. PMID 16562829 DOI: 10.1021/np058083q  0.44
2006 Homhual S, Zhang HJ, Bunyapraphatsara N, Kondratyuk TP, Santarsiero BD, Mesecar AD, Herunsalee A, Chaukul W, Pezzuto JM, Fong HH. Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Medica. 72: 255-60. PMID 16534731 DOI: 10.1055/s-2005-873171  0.44
2006 Jang DS, Su BN, Pawlus AD, Kang YH, Kardono LB, Riswan S, Afriastini JJ, Fong HH, Pezzuto JM, Kinghorn AD. Beccaridiol, an unusual 28-nortriterpenoid from the leaves of Diplectria beccariana. Phytochemistry. 67: 1832-7. PMID 16426647 DOI: 10.1016/j.phytochem.2005.11.026  0.44
2006 Zhang HJ, Ma C, Nguyen VH, Nguyen MC, Tan GT, Santarsiero BD, Mesecar AD, Soejarto DD, Pezzuto JM, Fong HH. Miliusanes, a class of cytotoxic agents from Miliusa sinensis. Journal of Medicinal Chemistry. 49: 693-708. PMID 16420055 DOI: 10.1021/jm0509492  0.44
2006 Gills JJ, Jeffery EH, Matusheski NV, Moon RC, Lantvit DD, Pezzuto JM. Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion. Cancer Letters. 236: 72-9. PMID 15993536 DOI: 10.1016/j.canlet.2005.05.007  0.44
2005 He ZD, Ma CY, Zhang HJ, Tan GT, Tamez P, Sydara K, Bouamanivong S, Southavong B, Soejarto DD, Pezzuto JM, Fong HH. Antimalarial constituents from Nauclea orientalis (L.) L. Chemistry & Biodiversity. 2: 1378-86. PMID 17191939 DOI: 10.1002/cbdv.200590110  0.44
2005 Lee HY, Oh SH, Woo JK, Kim WY, Van Pelt CS, Price RE, Cody D, Tran H, Pezzuto JM, Moriarty RM, Hong WK. Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. Journal of the National Cancer Institute. 97: 1695-9. PMID 16288123 DOI: 10.1093/jnci/dji377  0.44
2005 Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1. Analytical Chemistry. 77: 6407-14. PMID 16194107 DOI: 10.1021/ac050892r  0.44
2005 Jones WP, Lobo-Echeverri T, Mi Q, Chai H, Lee D, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Antitumour activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida. The Journal of Pharmacy and Pharmacology. 57: 1101-8. PMID 16105231 DOI: 10.1211/jpp.57.9.0005  0.44
2005 Gills JJ, Kosmeder J, Moon RC, Lantvit DD, Pezzuto JM. Effect of deguelin on UVB-induced skin carcinogenesis. Journal of Chemotherapy (Florence, Italy). 17: 297-301. PMID 16041863 DOI: 10.1179/joc.2005.17.3.297  0.44
2005 Jang DS, Su BN, Pawlus AD, Jones WP, Kleps RA, Bunyapraphatsara N, Fong HH, Pezzuto JM, Kinghorn AD. Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi. Journal of Natural Products. 68: 1134-6. PMID 16038568 DOI: 10.1021/np050132b  0.44
2005 Chow AW, Murillo G, Yu C, Van Breemen RB, Boddie AW, Pezzuto JM, Das Gupta TK, Mehta RG. Resveratrol inhibits rhabdomyosarcoma cell proliferation European Journal of Cancer Prevention. 14: 351-356. PMID 16030425 DOI: 10.1097/00008469-200508000-00007  0.44
2005 Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proceedings of the National Academy of Sciences of the United States of America. 102: 10070-5. PMID 16006525 DOI: 10.1073/pnas.0502402102  0.44
2005 Soejarto DD, Fong HH, Tan GT, Zhang HJ, Ma CY, Franzblau SG, Gyllenhaal C, Riley MC, Kadushin MR, Pezzuto JM, Xuan LT, Hiep NT, Hung NV, Vu BM, Loc PK, et al. Ethnobotany/ethnopharmacology and mass bioprospecting: issues on intellectual property and benefit-sharing. Journal of Ethnopharmacology. 100: 15-22. PMID 15993554 DOI: 10.1016/j.jep.2005.05.031  0.44
2005 Zhang HJ, Nguyen VH, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata. Planta Medica. 71: 452-7. PMID 15931585 DOI: 10.1055/s-2005-864142  0.44
2005 Koch A, Tamez P, Pezzuto J, Soejarto D. Evaluation of plants used for antimalarial treatment by the Maasai of Kenya Journal of Ethnopharmacology. 101: 95-99. PMID 15878245 DOI: 10.1016/j.jep.2005.03.011  0.44
2005 Mi Q, Lantvit D, Reyes-Lim E, Chai H, Phifer SS, Wani MC, Wall ME, Tan GT, Cordell GA, Farnsworth NR, Kinghorn AD, Pezzuto JM. Apoptotic anticancer effect of alvaradoin E isolated from Alvaradoa haitiensis. Anticancer Research. 25: 779-87. PMID 15868909  0.44
2005 Rivero-Cruz JF, Lezutekong R, Lobo-Echeverri T, Ito A, Mi Q, Chai HB, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Morelli I, Kinghorn AD. Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in Southern Florida. Phytotherapy Research : Ptr. 19: 136-40. PMID 15852485 DOI: 10.1002/ptr.1642  0.44
2005 Lobo-Echeverri T, Rivero-Cruz JF, Su BN, Chai HB, Cordell GA, Pezzuto JM, Swanson SM, Soejarto DD, Kinghorn AD. Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida. Journal of Natural Products. 68: 577-80. PMID 15844953 DOI: 10.1021/np0496688  0.44
2005 Tamez PA, Lantvit D, Lim E, Pezzuto JM. Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum. Journal of Ethnopharmacology. 98: 137-42. PMID 15763374 DOI: 10.1016/j.jep.2005.01.015  0.44
2005 Jacinto SD, Olarte EI, Galvez M, Villaseñor IM, Pezzuto JM. Leaf extract from Cassia alata L. ("Akapulko") induces quinone reductase and competes for estrogen receptor binding indicating cancer chemopreventive property Philippine Agricultural Scientist. 88: 175-178.  0.44
2005 Burns Kraft TF, Schmidt BM, Yousef GG, Knight CTG, Cuendet M, Kang YH, Pezzuto JM, Seigler DS, Lila MA. Chemopreventive potential of wild lowbush fruits in multiple stages of carcinogenisis Journal of Food Science. 70: S159-S166.  0.44
2004 Su BN, Jones WP, Cuendet M, Kardono LB, Ismail R, Riswan S, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2. Phytochemistry. 65: 2861-6. PMID 15501253 DOI: 10.1016/j.phytochem.2004.08.007  0.44
2004 Gafner S, Lee SK, Cuendet M, Barthélémy S, Vergnes L, Labidalle S, Mehta RG, Boone CW, Pezzuto JM. Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems Phytochemistry. 65: 2849-2859. PMID 15501252 DOI: 10.1016/j.phytochem.2004.08.008  0.44
2004 Jang DS, Cuendet M, Su BN, Totura S, Riswan S, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2 Planta Medica. 70: 893-896. PMID 15490314 DOI: 10.1055/s-2004-832612  0.44
2004 Pezzuto JM. Resveratrol: A whiff that induces a biologically specific tsunami Cancer Biology and Therapy. 3: 889-890. PMID 15467424  0.44
2004 Kinghorn AD, Su BN, Jang DS, Chang LC, Lee D, Gu JQ, Carcache-Blanco EJ, Pawlus AD, Lee SK, Park EJ, Cuendet M, Gills JJ, Bhat K, Park HS, Mata-Greenwood E, ... ... Pezzuto JM, et al. Natural inhibitors of carcinogenesis. Planta Medica. 70: 691-705. PMID 15326546 DOI: 10.1055/s-2004-827198  0.44
2004 Li Y, Grubjesic S, Nikolic D, Zhu D, Kosmeder JW, Moriarty RM, Pezzuto JM, Van Breemen RB. In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 535-47. PMID 15277014 DOI: 10.1080/00498250410001713159  0.44
2004 Gu JQ, Graf TN, Lee D, Chai HB, Mi Q, Kardono LB, Setyowati FM, Ismail R, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kroll DJ, Falkinham JO, et al. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. Journal of Natural Products. 67: 1156-61. PMID 15270571 DOI: 10.1021/np040027m  0.44
2004 Nguyen QC, Nguyen VH, Santarsiero BD, Mesecar AD, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. New 3-O-acyl betulinic acids from Strychnos vanprukii Craib. Journal of Natural Products. 67: 994-8. PMID 15217281 DOI: 10.1021/np030469i  0.44
2004 Christov KT, Moon RC, Lantvit DD, Boone CW, Kelloff GJ, Steele VE, Lubet RA, Pezzuto JM. Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies. European Journal of Cancer (Oxford, England : 1990). 40: 1404-11. PMID 15177500 DOI: 10.1016/j.ejca.2003.11.037  0.44
2004 Hwang BY, Su BN, Chai H, Mi Q, Kardono LB, Afriastini JJ, Riswan S, Santarsiero BD, Mesecar AD, Wild R, Fairchild CR, Vite GD, Rose WC, Farnsworth NR, Cordell GA, ... Pezzuto JM, et al. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. The Journal of Organic Chemistry. 69: 3350-8. PMID 15132542 DOI: 10.1021/jo040008h  0.44
2004 Jang DS, Cuendet M, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of Asparagus officinalis Evaluated for Inhibitory Activity against Cyclooxygenase-2 Journal of Agricultural and Food Chemistry. 52: 2218-2222. PMID 15080623 DOI: 10.1021/jf0305229  0.44
2004 Kang YH, Pezzuto JM. Induction of Quinone Reductase as a Primary Screen for Natural Product Anticarcinogens Methods in Enzymology. 382: 380-414. PMID 15047113 DOI: 10.1016/S0076-6879(04)82021-4  0.44
2004 Diaz F, Chai HB, Mi Q, Su BN, Vigo JS, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru. Journal of Natural Products. 67: 352-6. PMID 15043409 DOI: 10.1021/np030479j  0.44
2004 Rivero-Cruz JF, Chai HB, Kardono LB, Setyowati FM, Afriatini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Cytotoxic constituents of the twigs and leaves of Aglaia rubiginosa. Journal of Natural Products. 67: 343-7. PMID 15043407 DOI: 10.1021/np0304417  0.44
2004 Jang DS, Park EJ, Kang YH, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase. Archives of Pharmacal Research. 27: 169-72. PMID 15022717 DOI: 10.1007/BF02980101  0.44
2004 Cuendet M, Gills JJ, Pezzuto JM. Brusatol-induced HL-60 cell differentiation involves NF-κB activation Cancer Letters. 206: 43-50. PMID 15019158 DOI: 10.1016/j.canlet.2003.11.011  0.44
2004 Soejarto DD, Gyllenhaal C, Fong HH, Xuan LT, Hiep NT, Hung NV, Bich TQ, Southavong B, Sydara K, Pezzuto JM. The UIC ICBG (University of Illinois at Chicago International Cooperative Biodiversity Group) Memorandum of Agreement: a model of benefit-sharing arrangement in natural products drug discovery and development. Journal of Natural Products. 67: 294-9. PMID 14987071 DOI: 10.1021/np0304363  0.44
2004 Cuendet M, Pezzuto JM. Antitumor Activity of Bruceantin: An Old Drug with New Promise Journal of Natural Products. 67: 269-272. PMID 14987068 DOI: 10.1021/np030304+  0.44
2004 Ito A, Chai HB, Kardono LB, Setowati FM, Afriastini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Saponins from the bark of Nephelium maingayi. Journal of Natural Products. 67: 201-5. PMID 14987059 DOI: 10.1021/np030389e  0.44
2004 Zhang HJ, Sydara K, Tan GT, Ma C, Southavong B, Soejarto DD, Pezzuto JM, Fong HH. Bioactive constituents from Asparagus cochinchinensis. Journal of Natural Products. 67: 194-200. PMID 14987058 DOI: 10.1021/np030370b  0.44
2004 Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 11: 18-23. PMID 14974442 DOI: 10.1078/0944-7113-00331  0.44
2004 Cuendet M, Christov K, Lantvit DD, Deng Y, Hedayat S, Helson L, McChesney JD, Pezzuto JM. Multiple myeloma regression mediated by bruceantin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1170-9. PMID 14871997 DOI: 10.1158/1078-0432.CCR-0362-3  0.44
2004 Lee HY, Suh YA, Kosmeder JW, Pezzuto JM, Hong WK, Kurie JM. Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1074-9. PMID 14871987 DOI: 10.1158/1078-0432.CCR-0833-3  0.44
2004 Jang DS, Cuendet M, Pawlus AD, Kardono LB, Kawanishi K, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the leaves of Macaranga triloba. Phytochemistry. 65: 345-50. PMID 14751306 DOI: 10.1016/j.phytochem.2003.10.026  0.44
2004 Shin YG, Udeani GO, Kosmeder JW, Zhao GM, Dagar S, Onyuksel H, Moriarty RM, Cordell GA, Moon RC, Kinghorn AD, Pezzuto JM. Identification of Degradation Product of Deguelin and Its Stability Using Liquid Chromatography and Electrospray/Mass Spectrometry Journal of Liquid Chromatography and Related Technologies. 27: 1057-1069. DOI: 10.1081/JLC-120030178  0.44
2004 Kondratyuk TP, Pezzuto JM. Natural product polyphenols of relevance to human health Pharmaceutical Biology. 42: 46-63. DOI: 10.1080/13880200490893519  0.44
2003 Li Y, Shin YG, Yu C, Kosmeder JW, Hirschelman WH, Pezzuto JM, van Breemen RB. Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism. Combinatorial Chemistry & High Throughput Screening. 6: 757-67. PMID 14683481 DOI: 10.2174/138620703771826865  0.44
2003 Mi Q, Cui B, Lantvit D, Reyes-Lim E, Chai H, Pezzuto JM, Kinghorn AD, Swanson SM. Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance. Anticancer Research. 23: 3607-15. PMID 14666656  0.44
2003 Topcu G, Aydogmus Z, Imre S, Gören AC, Pezzuto JM, Clement JA, Kingston DG. Brominated sesquiterpenes from the red alga Laurencia obtusa. Journal of Natural Products. 66: 1505-8. PMID 14640529 DOI: 10.1021/np030176p  0.44
2003 Carcache-Blanco EJ, Kang YH, Park EJ, Su BN, Kardono LBS, Riswan S, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase Journal of Natural Products. 66: 1197-1202. PMID 14510596  0.44
2003 Jang DS, Park EJ, Kang YH, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria. Journal of Natural Products. 66: 1166-70. PMID 14510590 DOI: 10.1021/np0302100  0.44
2003 Jang DS, Park EJ, Kang YH, Su BN, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Archives of Pharmacal Research. 26: 585-90. PMID 12967190  0.44
2003 Burdette JE, Liu J, Chen SN, Fabricant DS, Piersen CE, Barker EL, Pezzuto JM, Mesecar A, Van Breemen RB, Farnsworth NR, Bolton JL. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. Journal of Agricultural and Food Chemistry. 51: 5661-70. PMID 12952416 DOI: 10.1021/jf034264r  0.44
2003 Su BN, Kang YH, Pinos RE, Santarsiero BD, Mesecar AD, Soejarto DD, Fong HH, Pezzuto JM, Kinghorn AD. Isolation and absolute stereochemistry of coussaric acid, a new bioactive triterpenoid from the stems of Coussarea brevicaulis. Phytochemistry. 64: 293-302. PMID 12946428 DOI: 10.1016/S0031-9422(03)00268-1  0.44
2003 Lee KH, Chai HB, Tamez PA, Pezzuto JM, Cordell GA, Win KK, Tin-Wa M. Biologically active alkylated coumarins from Kayea assamica. Phytochemistry. 64: 535-41. PMID 12943771 DOI: 10.1016/S0031-9422(03)00243-7  0.44
2003 Su BN, Park EJ, Nikolic D, Schunke Vigo J, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. Journal of Natural Products. 66: 1089-93. PMID 12932130 DOI: 10.1021/np030081n  0.44
2003 Tan Y, Yu R, Pezzuto JM. Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation Clinical Cancer Research. 9: 2866-2875. PMID 12855667  0.44
2003 Díaz F, Chávez D, Lee D, Mi Q, Chai HB, Tan GT, Kardono LB, Riswan S, Fairchild CR, Wild R, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. Journal of Natural Products. 66: 865-7. PMID 12828478 DOI: 10.1021/np0300784  0.44
2003 Topcu G, Altiner EN, Gozcu S, Halfon B, Aydogmus Z, Pezzuto JM, Zhou BN, Kingston DGI. Studies on di- and triterpenoids from Salvia staminea with cytotoxic activity Planta Medica. 69: 464-467. PMID 12802732 DOI: 10.1055/s-2003-39705  0.44
2003 Zhang HJ, Tan GT, Santarsiero BD, Mesecar AD, Hung NV, Cuong NM, Doel Soejarto D, Pezzuto JM, Fong HH. New Sesquiterpenes from Litsea verticillata. Journal of Natural Products. 66: 609-15. PMID 12762792 DOI: 10.1021/np020508a  0.44
2003 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). Journal of Natural Products. 66: 583-7. PMID 12762787 DOI: 10.1021/np020522n  0.44
2003 Fang L, Chai HB, Castillo JJ, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Brachistus stramoniifolius. Phytotherapy Research : Ptr. 17: 520-3. PMID 12748990 DOI: 10.1002/ptr.1315  0.44
2003 Su BN, Jung Park E, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. Phytochemistry. 63: 335-41. PMID 12737982 DOI: 10.1016/S0031-9422(03)00112-2  0.44
2003 Gu JQ, Li W, Kang YH, Su BN, Fong HHS, Van Breemen RB, Pezzuto JM, Kinghorn AD. Minor withanolides from Physalis philadelphica: Structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts Chemical and Pharmaceutical Bulletin. 51: 530-539. PMID 12736452  0.44
2003 Gafner S, Bergeron C, Batcha LL, Reich J, Arnason JT, Burdette JE, Pezzuto JM, Angerhofer CK. Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. Journal of Natural Products. 66: 535-7. PMID 12713409 DOI: 10.1021/np0205102  0.44
2003 Seo EK, Lee D, Shin YG, Chai HB, Navarro HA, Kardono LB, Rahman I, Cordell GA, Farnsworth NR, Pezzuto JM, Kinghorn AD, Wani MC, Wall ME. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Archives of Pharmacal Research. 26: 124-7. PMID 12643587  0.44
2003 Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. The Journal of Organic Chemistry. 68: 2350-61. PMID 12636402 DOI: 10.1021/jo020542u  0.44
2003 Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea. Journal of Natural Products. 66: 263-8. PMID 12608862 DOI: 10.1021/np020379y  0.44
2003 Chun KH, Kosmeder JW, Sun S, Pezzuto JM, Lotan R, Hong WK, Lee HY. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. Journal of the National Cancer Institute. 95: 291-302. PMID 12591985  0.44
2003 Omar S, Zhang J, MacKinnon S, Leaman D, Durst T, Philogene BJ, Arnason JT, Sanchez-Vindas PE, Poveda L, Tamez PA, Pezzuto JM. Traditionally-used antimalarials from the Meliaceae. Current Topics in Medicinal Chemistry. 3: 133-9. PMID 12570769 DOI: 10.2174/1568026033392499  0.44
2003 Yu C, Shin YG, Kosmeder JW, Pezzuto JM, van Breemen RB. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Communications in Mass Spectrometry : Rcm. 17: 307-13. PMID 12569440 DOI: 10.1002/rcm.918  0.44
2003 Duncan CJ, Cuendet M, Fronczek FR, Pezzuto JM, Mehta RG, Hamann MT, Ross SA. Chemical and biological investigation of the fungus Pulveroboletus ravenelii. Journal of Natural Products. 66: 103-7. PMID 12542354 DOI: 10.1021/np0203990  0.44
2003 Murillo G, Kosmeder JW, Pezzuto JM, Mehta RG. Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice. International Journal of Cancer. 104: 7-11. PMID 12532413 DOI: 10.1002/ijc.10901  0.44
2003 Hwang BY, Chai HB, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic triterpenes from the twigs of Celtis philippinensis. Phytochemistry. 62: 197-201. PMID 12482456 DOI: 10.1016/S0031-9422(02)00520-4  0.44
2003 Kinghorn AD, Su BN, Lee D, Gu JQ, Pezzuto JM. Cancer chemopreventive agents discovered by activity-guided fractionation: An update Current Organic Chemistry. 7: 213-226. DOI: 10.2174/1385272033373003  0.44
2003 Kinghorn AD, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Wani MC, Wall ME, Oberlies NH, Kroll DJ, Kramer RA, Rose WC, Vite GD, Fairchild CR, Peterson RW, et al. Novel strategies for the discovery of plant-derived anticancer agents Pharmaceutical Biology. 41: 53-67. DOI: 10.1080/1388020039051744  0.44
2003 Villinski JR, Dumas ER, Chai HB, Pezzuto JM, Angerhofer CK, Gafner S. Antibacterial activity and alkaloid content of Berberis thunbergii, Berberis vulgaris and Hydrastis canadensis Pharmaceutical Biology. 41: 551-557. DOI: 10.1080/13880200390500768  0.44
2003 Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HHS. Natural anti-HIV agents. Part 3: Litseaverticillols A-H, novel sesquiterpenes from Litsea verticillata Tetrahedron. 59: 141-148. DOI: 10.1016/S0040-4020(02)01491-6  0.44
2003 Su BN, Cuendet M, Nikolic D, Kristinsson H, Ingólfsdóttir K, Van Breemen RB, Fong HHS, Pezzuto JM, Kinghorn AD. NMR study of fumarprotocetraric acid, a complex lichen depsidone derivative from Cladonia furcata Magnetic Resonance in Chemistry. 41: 391-394. DOI: 10.1002/mrc.1181  0.44
2003 Pezzuto JM. Pharmaceutical biology: Foreword Pharmaceutical Biology. 41: 1.  0.44
2002 Xu H, Fabricant DS, Piersen CE, Bolton JL, Pezzuto JM, Fong H, Totura S, Farnsworth NR, Constantinou AI. A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health Phytomedicine. 9: 757-762. PMID 12587700 DOI: 10.1078/094471102321621403  0.44
2002 Yu C, Shin YG, Chow A, Li Y, Kosmeder JW, Lee YS, Hirschelman WH, Pezzuto JM, Mehta RG, van Breemen RB. Human, rat, and mouse metabolism of resveratrol. Pharmaceutical Research. 19: 1907-14. PMID 12523673 DOI: 10.1023/A:1021414129280  0.44
2002 Calderón AI, Terreaux C, Schenk K, Pattison P, Burdette JE, Pezzuto JM, Gupta MP, Hostettmann K. Isolation and structure elucidation of an isoflavone and a sesterterpenoic acid from Henriettella fascicularis. Journal of Natural Products. 65: 1749-53. PMID 12502307 DOI: 10.1021/np0201164  0.44
2002 Su BN, Cuendet M, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay. Planta Medica. 68: 1125-8. PMID 12494342 DOI: 10.1055/s-2002-36354  0.44
2002 Zhang HJ, Tamez PA, Aydogmus Z, Tan GT, Saikawa Y, Hashimoto K, Nakata M, Hung NV, Xuan le T, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva. Planta Medica. 68: 1088-91. PMID 12494335 DOI: 10.1055/s-2002-36350  0.44
2002 Jang DS, Cuendet M, Hawthorne ME, Kardono LBS, Kawanishi K, Fonga HHS, Mehta RG, Pezzuto JM, Kinghorn AD. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2 Phytochemistry. 61: 867-872. PMID 12453581 DOI: 10.1016/S0031-9422(02)00378-3  0.44
2002 Gu JQ, Park EJ, Vigo JS, Graham JG, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. Journal of Natural Products. 65: 1616-20. PMID 12444686 DOI: 10.1021/np020249p  0.44
2002 Burdette JE, Chen SN, Lu ZZ, Xu H, White BE, Fabricant DS, Liu J, Fong HH, Farnsworth NR, Constantinou AI, Van Breemen RB, Pezzuto JM, Bolton JL. Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. Journal of Agricultural and Food Chemistry. 50: 7022-8. PMID 12428954 DOI: 10.1021/jf020725h  0.44
2002 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. Journal of Agricultural and Food Chemistry. 50: 6330-4. PMID 12381112 DOI: 10.1021/jf0206670  0.44
2002 Su BN, Park EJ, Mbwambo ZH, Santarsiero BD, Mesecar AD, Fong HH, Pezzuto JM, Kinghorn AD. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. Journal of Natural Products. 65: 1278-82. PMID 12350147 DOI: 10.1021/np0202475  0.44
2002 Su BN, Chang LC, Park EJ, Cuendet M, Santarsiero BD, Mesecar AD, Mehta RG, Fong HH, Pezzuto JM, Kinghorn AD. Bioactive constituents of the seeds of Brucea javanica. Planta Medica. 68: 730-3. PMID 12221597 DOI: 10.1055/s-2002-33798  0.44
2002 Ito A, Chai HB, Lee D, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. Phytochemistry. 61: 171-4. PMID 12169311 DOI: 10.1016/S0031-9422(02)00232-7  0.44
2002 Mi Q, Cui B, Chávez D, Chai H, Zhu H, Cordell GA, Hedayat S, Kinghorn AD, Pezzuto JM. Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype. Anticancer Research. 22: 1385-97. PMID 12168815  0.44
2002 Blatt CT, Chávez D, Chai H, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. Phytotherapy Research : Ptr. 16: 320-5. PMID 12112286 DOI: 10.1002/ptr.889  0.44
2002 Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, Hollingshead MG, Mayo JG, Kinghorn AD, Pezzuto JM. Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay. Cancer Letters. 184: 13-20. PMID 12104043 DOI: 10.1016/S0304-3835(02)00202-1  0.44
2002 Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-Sánchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, ... Pezzuto JM, et al. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. Journal of Natural Products. 65: 842-50. PMID 12088425 DOI: 10.1021/np010322w  0.44
2002 Misico RI, Song LL, Veleiro AS, Cirigliano AM, Tettamanzi MC, Burton G, Bonetto GM, Nicotra VE, Silva GL, Gil RR, Oberti JC, Kinghorn AD, Pezzuto JM. Induction of quinone reductase by withanolides. Journal of Natural Products. 65: 677-80. PMID 12027740 DOI: 10.1021/np0106337  0.44
2002 Chávez D, Cui B, Chai HB, García R, Mejía M, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Reversal of multidrug resistance by tropane alkaloids from the stems of Erythroxylum rotundifolium. Journal of Natural Products. 65: 606-10. PMID 11975514 DOI: 10.1021/np0104774  0.44
2002 Gu JQ, Gills JJ, Park EJ, Mata-Greenwood E, Hawthorne ME, Axelrod F, Chavez PI, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. Journal of Natural Products. 65: 532-6. PMID 11975495 DOI: 10.1021/np010545m  0.44
2002 Minguzzi S, Barata LE, Shin YG, Jonas PF, Chai HB, Park EJ, Pezzuto JM, Cordell GA. Cytotoxic withanolides from Acnistus arborescens. Phytochemistry. 59: 635-41. PMID 11867095 DOI: 10.1016/S0031-9422(02)00022-5  0.44
2002 Peraza-Sánchez SR, Chai HB, Shin YG, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Constituents of the leaves and twigs of Ficus hispida. Planta Medica. 68: 186-8. PMID 11859479 DOI: 10.1055/s-2002-20257  0.44
2002 Hoang VD, Tan GT, Zhang HJ, Tamez PA, Hung NV, Cuong NM, Soejarto DD, Fong HH, Pezzuto JM. Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata. Phytochemistry. 59: 325-9. PMID 11830141 DOI: 10.1016/S0031-9422(01)00454-X  0.44
2002 Burdette JE, Liu J, Lantvit D, Lim E, Booth N, Bhat KP, Hedayat S, Van Breemen RB, Constantinou AI, Pezzuto JM, Farnsworth NR, Bolton JL. Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats. The Journal of Nutrition. 132: 27-30. PMID 11773503  0.44
2002 Zhang H, Qiu S, Tamez P, Tan GT, Aydogmus Z, Van Hung N, Cuong NM, Angerhofer C, Soejarto DD, Pezzuto JM, Fong HHS. Antimalarial agents from plants II. Decursivine, a new antimalarial indole alkaloid from Rhaphidophora decursiva Pharmaceutical Biology. 40: 221-224. DOI: 10.1076/phbi.40.3.221.5832  0.44
2002 Hedayat AS, Yan B, Pezzuto JM. Optimum designs for estimating EDp based on raw optical density data Journal of Statistical Planning and Inference. 104: 161-174. DOI: 10.1016/S0378-3758(01)00120-3  0.44
2002 Zhang H, Lu Z, Tan GT, Qiu S, Farnsworth NR, Pezzuto JM, Fong HHS. Polyacetyleneginsenoside-Ro, a novel triterpene saponin from Panax ginseng Tetrahedron Letters. 43: 973-977. DOI: 10.1016/S0040-4039(01)02310-3  0.44
2002 Su BN, Misico R, Jung Park E, Santarsiero BD, Mesecar AD, Fong HHS, Pezzuto JM, Douglas Kinghorn A. Isolation and characterization of bioactive principles of the leaves and stems of Physalis philadelphica Tetrahedron. 58: 3453-3466. DOI: 10.1016/S0040-4020(02)00277-6  0.44
2001 Constantinou AI, Lantvit D, Hawthorne M, Xu X, Van Breemen RB, Pezzuto JM. Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats Nutrition and Cancer. 41: 75-81. PMID 12094632  0.44
2001 Silva GL, Cui B, Chávez D, You M, Chai HB, Rasoanaivo P, Lynn SM, O'Neill MJ, Lewis JA, Besterman JM, Monks A, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters from Erythroxylum pervillei Journal of Natural Products. 64: 1514-1520. PMID 11754602 DOI: 10.1021/NP010295+  0.44
2001 Mata-Greenwood E, Daeuble JF, Grieco PA, Dou J, McChesney JD, Mehta RG, Kinghorn AD, Pezzuto JM. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. Journal of Natural Products. 64: 1509-13. PMID 11754601 DOI: 10.1021/np010212p  0.44
2001 Seo EK, Kim NC, Mi Q, Chai H, Wall ME, Wani MC, Navarro HA, Burgess JP, Graham JG, Cabieses F, Tan GT, Farnsworth NR, Pezzuto JM, Kinghorn AD. Macharistol, a new cytotoxic cinnamylphenol from the stems of Machaerium aristulatum. Journal of Natural Products. 64: 1483-5. PMID 11720542 DOI: 10.1021/np0103158  0.44
2001 Gu JQ, Park EJ, Luyengi L, Hawthorne ME, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity Phytochemistry. 58: 121-127. PMID 11524121 DOI: 10.1016/S0031-9422(01)00180-7  0.44
2001 Lee D, Cuendet M, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata. Organic Letters. 3: 2169-71. PMID 11440571 DOI: 10.1021/ol015985j  0.44
2001 Ito A, Cui B, Chávez D, Chai HB, Shin YG, Kawanishi K, Kardono LBS, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic polyacetylenes from the twigs of Ochanostachys amentacea Journal of Natural Products. 64: 246-248. PMID 11430012 DOI: 10.1021/np000484c  0.44
2001 Zhang HJ, Tamez PA, Vu DH, Ghee TT, Nguyen VH, Le TX, Le MH, Nguyen MC, Do TT, Soejarto DD, Fong HH, Pezzuto JM. Antimalarial compounds from Rhaphidophora decursiva. Journal of Natural Products. 64: 772-7. PMID 11421741 DOI: 10.1021/np010037c  0.44
2001 Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, Booth N, Constantinou AI, Pezzuto JM, Fong HH, Farnsworth NR, Bolton JL. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. Journal of Agricultural and Food Chemistry. 49: 2472-9. PMID 11368622 DOI: 10.1021/jf0014157  0.44
2001 Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, You M, Hollingshead MG, Mayo JG, Kinghorn AD, Pezzuto JM. Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype. Cancer Research. 61: 4030-7. PMID 11358822  0.44
2001 Correia SD, David JM, David JP, Chai HB, Pezzuto JM, Cordell GA. Alkyl phenols and derivatives from Tapirira obtusa. Phytochemistry. 56: 781-4. PMID 11314968 DOI: 10.1016/S0031-9422(00)00476-3  0.32
2001 Qiu SX, Nguyen VH, Le TX, Gu JQ, Lobkovsky E, Tran CK, Soejarto DD, Clardy J, Pezzuto JM, Dong Y, Mai VT, Le MH, Fong HH. A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography. Phytochemistry. 56: 775-80. PMID 11314967 DOI: 10.1016/S0031-9422(00)00463-5  0.44
2001 Horgen FD, Edrada RA, de los Reyes G, Agcaoili F, Madulid DA, Wongpanich V, Angerhofer CK, Pezzuto JM, Soejarto DD, Farnsworth NR. Biological screening of rain forest plot trees from Palawan Island (Philippines). Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 8: 71-81. PMID 11292242 DOI: 10.1078/0944-7113-00019  0.44
2001 Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HHS. Natural anti-HIV agents. Part 2: Litseaverticillol A, a prototypic litseane sesquiterpene from Litsea verticillata Tetrahedron Letters. 42: 8587-8591. DOI: 10.1016/S0040-4039(01)01852-4  0.44
2001 Chávez D, Chai HB, Chagwedera TE, Gao Q, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Novel stilbenes isolated from the root bark of Ekebergia benguelensis Tetrahedron Letters. 42: 3685-3688. DOI: 10.1016/S0040-4039(01)00560-3  0.44
2000 Kouzi SA, Chatterjee P, Pezzuto JM, Hamann MT. Microbial transformations of the antimelanoma agent betulinic acid. Journal of Natural Products. 63: 1653-7. PMID 11141108 DOI: 10.1021/np000343a  0.44
2000 Chang LC, Gills JJ, Bhat KPL, Luyengi L, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Cerbera manghas with antiproliferative and antiestrogenic activities Bioorganic and Medicinal Chemistry Letters. 10: 2431-2434. PMID 11078194  0.44
2000 Cho KH, Pezzuto JM, Bolton JL, Steele VE, Kelloff GJ, Lee SK, Constantinou A. Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity. European Journal of Cancer (Oxford, England : 1990). 36: 2146-56. PMID 11044654 DOI: 10.1016/S0959-8049(00)00300-2  0.44
2000 Chang LC, Song LL, Park EJ, Luyengi L, Lee KJ, Farnsworth NR, Pezzuto JM, Kinghorn AD. Bioactive constituents of Thuja occidentalis Journal of Natural Products. 63: 1235-1238. PMID 11000026 DOI: 10.1021/np0001575  0.44
2000 Qiu SX, Li XC, Xiong Y, Dong Y, Chai H, Farnsworth NR, Pezzuto JM, Fong HHS. Isolation and characterization of cytotoxic saponin chloromaloside a from Chlorophytum malayense Planta Medica. 66: 587-590. PMID 10985095 DOI: 10.1055/s-2000-8600  0.44
2000 Chatterjee P, Kouzi SA, Pezzuto JM, Hamann MT. Biotransformation of the antimelanoma agent betulinic acid by Bacillus megaterium ATCC 13368. Applied and Environmental Microbiology. 66: 3850-5. PMID 10966400 DOI: 10.1128/AEM.66.9.3850-3855.2000  0.44
2000 Nikolic D, Habibi-Goudarzi S, Corley DG, Gafner S, Pezzuto JM, van Breemen RB. Evaluation of cyclooxygenase-2 inhibitors using pulsed ultrafiltration mass spectrometry. Analytical Chemistry. 72: 3853-9. PMID 10959973 DOI: 10.1021/ac0000980  0.44
2000 Chang LC, Chávez D, Song LL, Farnsworth NR, Pezzuto JM, Kinghorn AD. Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea Organic Letters. 2: 515-518. PMID 10814365 DOI: 10.1021/ol990407c  0.44
2000 Peraza-Sánchez SR, Chávez D, Chai HB, Shin YG, García R, Mejía M, Fairchild CR, Lane KE, Menendez AT, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the roots of Ekmanianthe longiflora. Journal of Natural Products. 63: 492-5. PMID 10785421 DOI: 10.1021/np990528l  0.44
2000 Seo EK, Chai HB, Chagwedera TE, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. 5-(4-Hydroxyphenethenyl)-4,7-dimethoxycoumarin, a new constituent of Monotes engleri Planta Medica. 66: 182-184. PMID 10763599  0.44
1999 Cui B, Lee YH, Chai H, Tucker JC, Fairchild CR, Raventos-Suarez C, Long B, Lane KE, Menendez AT, Beecher CW, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic sesquiterpenoids from Ratibida columnifera. Journal of Natural Products. 62: 1545-50. PMID 10579870 DOI: 10.1021/np990260y  0.44
1999 Chung HS, Chang LC, Lee SK, Shamon LA, Van Breemen RB, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity Journal of Agricultural and Food Chemistry. 47: 36-41. PMID 10563845 DOI: 10.1021/jf980784o  0.44
1999 Ito A, Lee YH, Chai HB, Gupta MP, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. 1',2',3',4'-Tetradehydrotubulosine, a cytotoxic alkaloid from Pogonopus speciosus Journal of Natural Products. 62: 1346-1348. PMID 10514334 DOI: 10.1021/np990255u  0.44
1999 Cui B, Chai H, Dong Y, Horgen FD, Hansen B, Madulid DA, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Quinoline alkaloids from Acronychia laurifolia Phytochemistry. 52: 95-98. PMID 10466225 DOI: 10.1016/S0031-9422(99)00039-4  0.44
1999 Chatterjee P, Pezzuto JM, Kouzi SA. Glucosidation of betulinic acid by Cunninghamella species. Journal of Natural Products. 62: 761-3. PMID 10346964 DOI: 10.1021/np980432b  0.44
1999 Qiu SX, Lu ZZ, Luyengi L, Lee SK, Pezzuto JM, Farnsworth NR, Thompson LU, Fong HHS. Isolation and characterization of flaxseed (Linum usitatissimum) constituents Pharmaceutical Biology. 37: 1-7. DOI: 10.1076/phbi.37.1.1.6320  0.44
1998 El Sayed KA, Hamann MT, Waddling CA, Jensen C, Lee SK, Dunstan CA, Pezzuto JM. Structurally Novel Bioconversion Products of the Marine Natural Product Sarcophine Effectively Inhibit JB6 Cell Transformation. The Journal of Organic Chemistry. 63: 7449-7455. PMID 11672397 DOI: 10.1021/jo9813134  0.44
1998 Jang M, Pezzuto JM. Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin Cancer Letters. 134: 81-89. PMID 10381133 DOI: 10.1016/S0304-3835(98)00250-X  0.44
1998 Qiu SX, Sun HD, Lobkovsky E, Chai H, Clardy J, Farnsworth NR, Pezzuto JM, Fong HHS. Megathyrin B: A cytotoxic diterpene from isodon megathyrsus Planta Medica. 64: 728-731. PMID 10075544 DOI: 10.1055/s-2006-957567  0.44
1998 Cui B, Chai H, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Novel cytotoxic acylated oligorhamnosides from Mezzettia leptopoda Journal of Natural Products. 61: 1535-1538. PMID 9868159 DOI: 10.1021/np980270j  0.44
1998 Chang LC, Bhat KPL, Pisha E, Kennelly EJ, Fong HHS, Pezzuto JM, Kinghorn AD. Activity-guided isolation of steroidal alkaloid antiestrogen-binding site inhibitors from Pachysandra procumbens Journal of Natural Products. 61: 1257-1262. PMID 9784163 DOI: 10.1021/np980162x  0.44
1998 Poobrasert O, Constant HL, Beecher CWW, Farnsworth NR, Kinghorn AD, Pezzuto JM, Cordell GA, Santisuk T, Reutrakul V. Xanthones from the twigs of Mammea siamensis Phytochemistry. 47: 1661-1663. PMID 9612959 DOI: 10.1016/S0031-9422(97)00820-0  0.44
1998 Cui B, Chai H, Constant HL, Santisuk T, Reutrakul V, Beecher CWW, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Limonoids from Azadirachta excelsa Phytochemistry. 47: 1283-1287. PMID 9611828 DOI: 10.1016/S0031-9422(97)00711-5  0.44
1998 David JM, Chávez JP, Chai HB, Pezzuto JM, Cordell GA. Two new cytotoxic compounds from Tapirira guianensis. Journal of Natural Products. 61: 287-9. PMID 9514013 DOI: 10.1021/np970422v  0.32
1998 Jang M, Pezzuto JM. Resveratrol blocks eicosanoid production and chemically-induced cellular transformation: Implications for cancer chemoprevention Pharmaceutical Biology. 36: 28-34. DOI: 10.1076/phbi.36.6.28.4553  0.44
1998 Ito A, Shamon LA, Yu B, Mata-Greenwood E, Lee SK, Van Breemen RB, Mehta RG, Farnsworth NR, Fong HHS, Pezzuto JM, Kinghorn AD. Antimutagenic Constituents of Casimiroa edulis with Potential Cancer Chemopreventive Activity Journal of Agricultural and Food Chemistry. 46: 3509-3516.  0.44
1997 Bolton JL, Pisha E, Shen L, Krol ES, Iverson SL, Huang Z, Van Breemen RB, Pezzuto JM. The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells Chemico-Biological Interactions. 106: 133-148. PMID 9366899 DOI: 10.1016/S0009-2797(97)00066-5  0.44
1997 Seo EK, Silva GL, Chai HB, Chagwedera TE, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic prenylated flavanones from Monotes engleri. Phytochemistry. 45: 509-15. PMID 9190085  0.32
1997 Horgen FD, Guinaudeau H, Pezzuto JM, Soejarto DD, Farnsworth NR, Agcaoili F, de los Reyes G, Edrada RA. Isolation and structure elucidation of ardisenone: a new, cytotoxic alkenylphenol from Ardisia iwahigensis. Journal of Natural Products. 60: 533-5. PMID 9170297 DOI: 10.1021/np970049r  0.44
1997 Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, Van Breemen RB, Bolton JL. Bioreductive activation of catechol estrogen-ortho-quinones: Aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity Carcinogenesis. 18: 1093-1101. PMID 9163701 DOI: 10.1093/carcin/18.5.1093  0.44
1997 Caliş I, Yürüker A, Taşdemir D, Wright AD, Sticher O, Luo YD, Pezzuto JM. Cycloartane triterpene glycosides from the roots of Astragalus melanophrurius. Planta Medica. 63: 183-6. PMID 9140236  0.44
1997 Mossa JS, El-Feraly FS, Muhammad I, Zaw K, Mbwambo ZH, Pezzuto JM, Fong HHS. Sesquiterpene lactones and thymol esters from Vicoa pentanema Journal of Natural Products. 60: 550-555. DOI: 10.1021/np960506o  0.44
1997 Chung MS, Kim NC, Long L, Shamon L, Ahmad WY, Sagrero-Nieves L, Kardono LBS, Kennelly EJ, Pezzuto JM, Soejarto DD, Kinghorn AD. Dereplication of saccharide and polyol constituents of candidate sweet-tasting plants: Isolation of the sesquiterpene glycoside mukurozioside IIb as a sweet principle of Sapindus rarak Phytochemical Analysis. 8: 49-54. DOI: 10.1002/(SICI)1099-1565(199703)8:2<49::AID-PCA339>3.0.CO;2-C  0.44
1997 Kennelly EJ, Gerhäuser C, Song LL, Graham JG, Beecher CWW, Pezzuto JM, Kinghorn AD. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos) Journal of Agricultural and Food Chemistry. 45: 3771-3777.  0.44
1996 Pengsuparp T, Serit M, Hughes SH, Soejarto DD, Pezzuto JM. Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of Calophyllum teysmannii Journal of Natural Products. 59: 839-842. PMID 8864237 DOI: 10.1021/np960399y  0.44
1996 Sturm S, Gil RR, Chai HB, Ngassapa OD, Santisuk T, Reutrakul V, Howe A, Moss M, Besterman JM, Yang SL, Farthing JE, Tait RM, Lewis JA, O'Neill MJ, Farnsworth NR, ... ... Pezzuto JM, et al. Lupane derivatives from Lophopetalum wallichii with farnesyl protein transferase inhibitory activity. Journal of Natural Products. 59: 658-63. PMID 8759161 DOI: 10.1021/np960370u  0.32
1996 Lee IS, Shamon LA, Chai HB, Chagwedera TE, Besterman JM, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cell-cycle specific cytotoxicity mediated by rearranged ent-kaurene diterpenoids isolated from Parinari curatellifolia. Chemico-Biological Interactions. 99: 193-204. PMID 8620568  0.32
1996 Tan GT, Lee S, Lee IS, Chen J, Leitner P, Besterman JM, Kinghorn AD, Pezzuto JM. Natural-product inhibitors of human DNA ligase I. The Biochemical Journal. 314: 993-1000. PMID 8615799  0.44
1995 Leaman DJ, Arnason JT, Yusuf R, Sangat-Roemantyo H, Soedjito H, Angerhofer CK, Pezzuto JM. Malaria remedies of the Kenyah of the Apo Kayan, East Kalimantan, Indonesian Borneo: A quantitative assessment of local consensus as an indicator of biological efficacy Journal of Ethnopharmacology. 49: 1-16. PMID 8786652 DOI: 10.1016/0378-8741(95)01289-3  0.44
1995 Wickramaratne DBM, Mar W, Chai H, Castillo JJ, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Bursera permollis Planta Medica. 61: 80-81. PMID 7701001 DOI: 10.1055/s-2006-958008  0.44
1995 You M, Wickramaratne DB, Silva GL, Chai H, Chagwedera TE, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. (-)-Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cells. Journal of Natural Products. 58: 598-604. PMID 7623038  0.44
1995 Silva GL, Chai H, Gupta MP, Farnsworth NR, Cordell GA, Pezzuto JM, Beecher CW, Kinghorn AD. Cytotoxic biflavonoids from Selaginella willdenowii. Phytochemistry. 40: 129-34. PMID 7546547  0.44
1995 Falch BS, König GM, Wright AD, Sticher O, Angerhofer CK, Pezzuto JM, Bachmann H. Biological activities of cyanobacteria: evaluation of extracts and pure compounds. Planta Medica. 61: 321-8. PMID 7480178 DOI: 10.1055/s-2006-958092  0.44
1995 Kennelly EJ, Cai L, Long L, Shamon L, Zaw K, Zhou BN, Pezzuto JM, Kinghorn AD. Novel highly sweet secodammarane glycosides from Pterocarya paliurus Journal of Agricultural and Food Chemistry. 43: 2602-2607.  0.44
1994 Ngassapa O, Soejarto DD, Pezzuto JM, Farnsworth NR. Quinone-methide triterpenes and salaspermic acid from Kokoona ochracea Journal of Natural Products. 57: 1-8. PMID 8158155 DOI: 10.1021/np50103a001  0.44
1994 Fullas F, Hussain RA, Chai HB, Pezzuto JM, Soejarto DD, Douglas Kinghorn A. Cytotoxic constituents of Baccharis gaudichaudiana Journal of Natural Products. 57: 801-807. PMID 7931367 DOI: 10.1021/np50108a017  0.44
1994 You M, Ma X, Mukherjee R, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. Indole alkaloids from Peschiera laeta that enhance vinblastine-mediated cytotoxicity with multidrug-resistant cells. Journal of Natural Products. 57: 1517-22. PMID 7853002  0.32
1994 König GM, Wright AD, Sticher O, Angerhofer CK, Pezzuto JM. Biological activities of selected marine natural products. Planta Medica. 60: 532-7. PMID 7809206 DOI: 10.1055/s-2006-959565  0.44
1994 Ma X, Lee IS, Chai HB, Zaw K, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, D. Kinghorn A. Cytotoxic clerodane diterpenes from Polyalthia barnesii Phytochemistry. 37: 1659-1662. PMID 7766002 DOI: 10.1016/S0031-9422(00)89587-4  0.44
1993 Pereda-Miranda R, Hernández L, Villavicencio MJ, Novelo M, Ibarra P, Chai H, Pezzuto JM. Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata. Journal of Natural Products. 56: 583-93. PMID 8496706 DOI: 10.1021/np50094a019  0.44
1993 Ngassapa O, Beecher CW, Pezzuto JM, Farnsworth NR, Henderson TO, Boye GL. Isolation of echinocystic acid-3-O-sulfate, a new triterpene, from Tetrapleura tetraptera, and evaluation of the mutagenic potential of molluscicidal extracts and isolates. Journal of Natural Products. 56: 1872-7. PMID 8289059 DOI: 10.1021/np50101a002  0.32
1993 Ngassapa O, Soejarto DD, Pezzuto JM, Farnsworth NR, Che CT. Further lupane lactones from Kokoona ochracea Journal of Natural Products. 56: 1676-1681. PMID 8277307 DOI: 10.1021/np50100a003  0.44
1993 Baek NI, Chung MS, Shamon L, Kardono LBS, Tsauri S, Padmawinata K, Pezzuto JM, Soejarto DD, Kinghorn AD. Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feei Journal of Natural Products. 56: 1532-1538. PMID 8254348 DOI: 10.1021/np50099a011  0.44
1993 Wickramaratne DB, Pengsuparp T, Mar W, Chai HB, Chagwedera TE, Beecher CW, Farnsworth NR, Kinghorn AD, Pezzuto JM, Cordell GA. Novel antimitotic dibenzocyclo-octadiene lignan constituents of the stem bark of Steganotaenia araliacea. Journal of Natural Products. 56: 2083-90. PMID 8133298  0.32
1992 Kaneda N, Pezzuto JM, Kinghorn AD, Farnsworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V. Plant anticancer agents, L. cytotoxic triterpenes from Sandoricum koetjape stems Journal of Natural Products. 55: 654-659. PMID 1517737  0.44
1992 Kaneda N, Chai H, Pezzuto JM, Kinghorn AD, Farnsworth NR, Tuchinda P, Udchachon J, Santisuk T, Reutrakul V. Cytotoxic activity of cardenolides from Beaumontia brevituba stems Planta Medica. 58: 429-431. PMID 1470666 DOI: 10.1055/s-2006-961506  0.44
1992 Tan GT, Miller JF, Kinghorn AD, Hughes SH, Pezzuto JM. HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products. Biochemical and Biophysical Research Communications. 185: 370-8. PMID 1376118  0.44
1992 Angerhofer CK, Pezzuto JM, König GM, Wright AD, Sticher O. Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra. Journal of Natural Products. 55: 1787-9. PMID 1294700  0.44
1991 Kaneda N, Pezzuto JM, Soejarto DD, Kinghorn AD, Farnsworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V. Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots Journal of Natural Products. 54: 196-206. PMID 2045815  0.44
1991 Pezzuto JM, Che CT, McPherson DD, Zhu JP, Topcu G, Erdelmeier CA, Cordell GA. DNA as an affinity probe useful in the detection and isolation of biologically active natural products. Journal of Natural Products. 54: 1522-30. PMID 1812211 DOI: 10.1021/np50078a006  0.32
1991 Ngassapa OD, Soejarto DD, Che CT, Pezzuto JM, Farnsworth NR. New cytotoxic lupane lactones from Kokoona ochracea Journal of Natural Products. 54: 1353-1359. PMID 1800637 DOI: 10.1021/np50077a019  0.44
1991 Mar W, Tan GT, Cordell GA, Pezzuto JM, Jurcic K, Offermann F, Redl K, Steinke B, Wagner H. Biological activity of novel macrocyclic alkaloids (budmunchiamines) from Albizia amara detected on the basis of interaction with DNA. Journal of Natural Products. 54: 1531-42. PMID 1725878 DOI: 10.1021/np50078a007  0.32
1991 Tan GT, Pezzuto JM, Kinghorn AD, Hughes SH. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Journal of Natural Products. 54: 143-54. PMID 1710653  0.44
1991 Fullas F, Hussain RA, Bordas E, Pezzuto JM, Soejarto DD, Kinghorn AD. Gaudichaudiosides A-E, five novel diterpene glycoside constituents from the sweet-tasting plant, Baccharis gaudichaudiana Tetrahedron. 47: 8515-8522. DOI: 10.1016/S0040-4020(01)82394-2  0.44
1991 Tuchinda P, Udchachon J, Reutrakul V, Santisuk T, Taylor WC, Farnsworth NR, Pezzuto JM, Kinghorn AD. Bioactive butenolides from Melodorum fruticosum Phytochemistry. 30: 2685-2689. DOI: 10.1016/0031-9422(91)85123-H  0.44
1991 Konig GM, Wright AD, Sticher O, Jurcic K, Offermann F, Redl K, Wagner H, Angerhofer CK, Pezzuto JM. Structure elucidation and biological activity of secondary metabolites from marine red and brown algae Planta Medica. 57: A5.  0.44
1990 Kaneda N, Pezzuto JM, Soejarto DD, Kinghorn AD, Farnsworth NR, Tuchinda P, Udchachon J, Santisuk T, Reutrakul V. New cytotoxic flavonoids from Muntingia calabura roots Planta Medica. 56: 672-673. DOI: 10.1055/s-2006-961339  0.44
1990 Hussain RA, Poveda LJ, Pezzuto JM, Soejarto DD, Kinghorn AD. Sweetening agents of plant origin: Phenylpropanoid constituents of seven sweet-tasting plants Economic Botany. 44: 174-182. DOI: 10.1007/BF02860485  0.44
1989 Jayasuriya H, McChesney JD, Swanson SM, Pezzuto JM. Antimicrobial and cytotoxic activity of rottlerin-type compounds from Hypericum drummondii. Journal of Natural Products. 52: 325-31. PMID 2746258 DOI: 10.1021/np50062a018  0.44
1989 Braun RJ, Pezzuto JM, Anderson CH, Beattie CW. Estrous cycle status alters N-methyl-N-nitrosourea (NMU)-induced rat mammary tumor growth and regression. Cancer Letters. 48: 205-11. PMID 2605569 DOI: 10.1016/0304-3835(89)90119-5  0.44
1988 Compadre CM, Hussain RA, de Compadre Lopez RL, Pezzuto JM, Kinghorn AD. Analysis of structural features responsible for the sweetness of the sesquiterpene, hernandulcin Experientia. 44: 447-449. PMID 3371450 DOI: 10.1007/BF01940543  0.44
1988 Compadre CM, Hussain RA, Nanayakkara NPD, Pezzuto JM, Kinghorn AD. Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside a, and rubusoside Biomedical &Amp; Environmental Mass Spectrometry. 15: 211-222. PMID 3370361 DOI: 10.1002/bms.1200150405  0.44
1988 Kim J, Pezzuto JM, Soejarto DD, Lang FA, Kinghorn AD. Polypodoside A, an intensely sweet constituent of the rhizomes of Polypodium glycyrrhiza Journal of Natural Products. 51: 1166-1172. PMID 3236009 DOI: 10.1021/np50060a019  0.44
1987 Braun RJ, Ratko TA, Pezzuto JM, Beattie CW. Estrous cycle modification of rat uterine DNA alkylation by N-methyl-N-nitrosourea. Cancer Letters. 37: 345-52. PMID 3677066 DOI: 10.1016/0304-3835(87)90120-0  0.44
1987 Nanayakkara NPD, Klocke JA, Compadre CM, Hussain RA, Pezzuto JM, Kinghorn AD. Characterization and feeding deterrent effects on the aphid, Schizaphis graminum, of some derivatives of the sweet compounds, stevioside and rebaudioside A Journal of Natural Products. 50: 434-441. PMID 3668559 DOI: 10.1021/np50051a015  0.44
1987 Duh CY, Pezzuto JM, Kinghorn AD, Leung SL, Farnsworth NR. Plant anticancer agents XLIV. Cytotoxic constituents from Stizophyllum riparium. Journal of Natural Products. 50: 63-74. PMID 3598599  0.44
1986 Pezzuto JM, Dhammika Nanayakkara NP, Compadre CM, Swanson SM, Kinghorn AD, Guenthner TM, Sparnins VL, Lam LKT. Characterization of bacterial mutagenicity mediated by 13-hydroxy-ent-kaurenoic acid (steviol) and several structurally-related derivatives and evaluation of potential to induce glutathione S-transferase in mice Mutation Research/Genetic Toxicology. 169: 93-103. PMID 3512998 DOI: 10.1016/0165-1218(86)90088-1  0.44
1985 Pezzuto JM, Compadre CM, Swanson SM, Nanayakkara D, Kinghorn AD. Metabolically activated steviol, the aglycone of stevioside, is mutagenic Proceedings of the National Academy of Sciences of the United States of America. 82: 2478-2482. PMID 3887402 DOI: 10.1073/pnas.82.8.2478  0.44
1985 Compadre CM, Pezzuto JM, Kinghorn AD, Kamath SK. Hernandulcin: An intensely sweet compound discovered by review of ancient literature Science. 227: 417-419. PMID 3880922 DOI: 10.1126/science.3880922  0.44
1985 Fiebig M, Pezzuto JM, Soejarto DD, Kinghorn AD. Koenoline, a further cytotoxic carbazole alkaloid from Murraya koenigii Phytochemistry. 24: 3041-3043. DOI: 10.1016/0031-9422(85)80052-2  0.44
1984 Marcelle GB, Ahmed MS, Pezzuto JM, Cordell GA, Waller DP, Soejarto DD, Fong HH. Analysis of gossypol and gossypol-acetic acid by high-performance liquid chromatography. Journal of Pharmaceutical Sciences. 73: 396-8. PMID 6716251 DOI: 10.1002/jps.2600730328  0.44
1983 Pezzuto JM, Antosiak SK, Messmer WM, Slaytor MB, Honig GR. Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids. Chemico-Biological Interactions. 43: 323-39. PMID 6337734 DOI: 10.1016/0009-2797(83)90116-3  0.44
1983 McPherson DD, Cordell GA, Soejarto DD, Pezzuto JM, Fong HHS. Peltogynoids and homoisoflavonoids from Caesalpinia pulcherrima Phytochemistry. 22: 2835-2838. DOI: 10.1016/S0031-9422(00)97708-2  0.44
1980 Pezzuto JM, Lau PP, Luh Y, Moore PD, Wogan GN, Hecht SM. There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles Proceedings of the National Academy of Sciences of the United States of America. 77: 1427-1431. PMID 6990411 DOI: 10.1073/pnas.77.3.1427  0.44
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