| Year |
Citation |
Score |
| 2023 |
Anderson BD, Lee TT, Bell BA, Wang T, Dunaief JL. Optimizing the sodium iodate model: Effects of dose, gender, and age. Experimental Eye Research. 109772. PMID 38158173 DOI: 10.1016/j.exer.2023.109772 |
0.317 |
|
| 2023 |
Anderson BD, Lee T, Bell B, Song Y, Dunaief JL. Low ceruloplasmin levels exacerbate retinal degeneration in a hereditary hemochromatosis model. Disease Models & Mechanisms. 16. PMID 37439255 DOI: 10.1242/dmm.050226 |
0.576 |
|
| 2023 |
Zhang KR, Jankowski CSR, Marshall R, Nair R, Gómez NM, Alnemri A, Liu Y, Erler E, Ferrante J, Song Y, Bell BA, Baumann BH, Sterling J, Anderson B, Foshe S, ... ... Dunaief JL, et al. Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells. Disease Models & Mechanisms. PMID 37401371 DOI: 10.1242/dmm.050066 |
0.842 |
|
| 2022 |
Perzia BM, Ying GS, Dunaief JL, Dunaief DM. Reduction in Ferritin Concentrations among Patients Consuming a Dark-Green Leafy Vegetable-Rich, Low Inflammatory Foods Everyday (LIFE) Diet. Current Developments in Nutrition. 6: nzac095. PMID 35769450 DOI: 10.1093/cdn/nzac095 |
0.436 |
|
| 2022 |
Sterling JK, Baumann B, Foshe S, Voigt A, Guttha S, Alnemri A, McCright SJ, Li M, Zauhar RJ, Montezuma SR, Kapphahn RJ, Chavali VRM, Hill DA, Ferrington DA, Stambolian D, ... ... Dunaief JL, et al. Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction. Cell Reports. 39: 110942. PMID 35705048 DOI: 10.1016/j.celrep.2022.110942 |
0.85 |
|
| 2022 |
Zhang KR, Baumann B, Song Y, Sterling J, Erler EA, Guttha S, Kozmik Z, Dunaief JL. Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis. Experimental Eye Research. 218: 109028. PMID 35271829 DOI: 10.1016/j.exer.2022.109028 |
0.88 |
|
| 2022 |
Liu Y, Bell BA, Song Y, Zhang K, Anderson B, Axelsen PH, Bohannan W, Agbaga MP, Park HG, James G, Brenna JT, Schmidt K, Dunaief JL, Shchepinov MS. Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload. Aging Cell. e13579. PMID 35257475 DOI: 10.1111/acel.13579 |
0.535 |
|
| 2022 |
Liu Y, Baumann B, Song Y, Zhang K, Sterling JK, Lakhal-Littleton S, Kozmik Z, Su G, Dunaief JL. Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration. Experimental Eye Research. 218: 108988. PMID 35202704 DOI: 10.1016/j.exer.2022.108988 |
0.881 |
|
| 2022 |
Huang S, Liu CH, Wang Z, Fu Z, Britton WR, Blomfield AK, Kamenecka TM, Dunaief JL, Solt LA, Chen J. REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2. Redox Biology. 51: 102261. PMID 35176707 DOI: 10.1016/j.redox.2022.102261 |
0.325 |
|
| 2022 |
Sterling JK, Kam TI, Guttha S, Park H, Baumann B, Mehrabani-Tabari AA, Schultz H, Anderson B, Alnemri A, Chou SC, Troncoso JC, Dawson VL, Dawson TM, Dunaief JL. Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein. Cell Reports. 38: 110358. PMID 35172141 DOI: 10.1016/j.celrep.2022.110358 |
0.809 |
|
| 2022 |
Chuang JZ, Yang N, Nakajima N, Otsu W, Fu C, Yang HH, Lee MP, Akbar AF, Badea TC, Guo Z, Nuruzzaman A, Hsu KS, Dunaief JL, Sung CH. Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration. Nature Communications. 13: 374. PMID 35042858 DOI: 10.1038/s41467-021-27935-9 |
0.364 |
|
| 2021 |
Kim BJ, Lee V, Lee EB, Saludades A, Trojanowski JQ, Dunaief JL, Grossman M, Irwin DJ. Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau. Acta Neuropathologica Communications. 9: 184. PMID 34794500 DOI: 10.1186/s40478-021-01290-8 |
0.3 |
|
| 2021 |
Liu Y, Bell BA, Song Y, Kim HJ, Sterling JK, Kim BJ, Poli M, Guo M, Zhang K, Rao A, Sparrow JR, Su G, Dunaief JL. Intraocular iron injection induces oxidative stress followed by elements of geographic atrophy and sympathetic ophthalmia. Aging Cell. e13490. PMID 34626070 DOI: 10.1111/acel.13490 |
0.868 |
|
| 2021 |
Guo M, Schwartz TD, Dunaief JL, Cui QN. Myeloid cells in retinal and brain degeneration. The Febs Journal. PMID 34478598 DOI: 10.1111/febs.16177 |
0.593 |
|
| 2021 |
Sterling J, Hua P, Dunaief JL, Cui QN, VanderBeek BL. Glucagon-like peptide 1 receptor agonist use is associated with reduced risk for glaucoma. The British Journal of Ophthalmology. PMID 34413054 DOI: 10.1136/bjophthalmol-2021-319232 |
0.784 |
|
| 2021 |
Zhao J, Kim HJ, Ueda K, Zhang K, Montenegro D, Dunaief JL, Sparrow JR. A vicious cycle of bisretinoid formation and oxidation relevant to recessive Stargardt disease. The Journal of Biological Chemistry. 296: 100259. PMID 33837742 DOI: 10.1016/j.jbc.2021.100259 |
0.598 |
|
| 2021 |
Zhao J, Kim HJ, Ueda K, Zhang K, Montenegro D, Dunaief JL, Sparrow JR. A vicious cycle of bisretinoid formation and oxidation relevant to recessive Stargardt disease. The Journal of Biological Chemistry. PMID 33402423 DOI: 10.1074/jbc.RA120.015890 |
0.583 |
|
| 2020 |
Sterling JK, Adetunji MO, Guttha S, Bargoud AR, Uyhazi KE, Ross AG, Dunaief JL, Cui QN. GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension. Cell Reports. 33: 108271. PMID 33147455 DOI: 10.1016/j.celrep.2020.108271 |
0.785 |
|
| 2020 |
Kim BJ, Hunter A, Brucker AJ, Hahn P, Gehrs K, Patel A, Edwards AO, Li Y, Khurana RN, Nissim I, Daniel E, Grunwald J, Ying GS, Pistilli M, Maguire MG, ... Dunaief JL, et al. Orally Administered Alpha Lipoic Acid as a Treatment for Geographic Atrophy: A Randomized Clinical Trial. Ophthalmology. Retina. PMID 32418846 DOI: 10.1016/J.Oret.2020.03.019 |
0.385 |
|
| 2020 |
Shu W, Baumann BH, Song Y, Liu Y, Wu X, Dunaief JL. Ferrous but not ferric iron sulfate kills photoreceptors and induces photoreceptor-dependent RPE autofluorescence. Redox Biology. 101469. PMID 32362442 DOI: 10.1016/j.redox.2020.101469 |
0.503 |
|
| 2020 |
Bellsmith KN, Dunaief JL, Yang P, Pennesi ME, Davis E, Hofkamp H, Lujan BJ. Bull's eye maculopathy associated with hereditary hemochromatosis. American Journal of Ophthalmology Case Reports. 18: 100674. PMID 32258826 DOI: 10.1016/j.ajoc.2020.100674 |
0.319 |
|
| 2020 |
Cui QN, Bargoud AR, Ross AG, Song Y, Dunaief JL. Oral administration of the iron chelator deferiprone protects against loss of retinal ganglion cells in a mouse model of glaucoma. Experimental Eye Research. 107961. PMID 32045598 DOI: 10.1016/j.exer.2020.107961 |
0.681 |
|
| 2019 |
Shu W, Baumann BH, Song Y, Liu Y, Wu X, Dunaief JL. Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice. Investigative Ophthalmology & Visual Science. 60: 4378-4387. PMID 31634395 DOI: 10.1167/iovs.19-28250 |
0.585 |
|
| 2019 |
Klee K, Storti F, Barben M, Samardzija M, Langmann T, Dunaief J, Grimm C. Systemic knockout of Tspo in mice does not affect retinal morphology, function and susceptibility to degeneration. Experimental Eye Research. 188: 107816. PMID 31562844 DOI: 10.1016/J.Exer.2019.107816 |
0.529 |
|
| 2019 |
Khan RS, Baumann B, Dine K, Song Y, Dunaief JL, Kim SF, Shindler KS. Dexras1 Deletion and Iron Chelation Promote Neuroprotection in Experimental Optic Neuritis. Scientific Reports. 9: 11664. PMID 31406150 DOI: 10.1038/s41598-019-48087-3 |
0.383 |
|
| 2019 |
Baumann BH, Shu W, Song Y, Simpson EM, Lakhal-Littleton S, Dunaief JL. Ferroportin-mediated iron export from vascular endothelial cells in retina and brain. Experimental Eye Research. 107728. PMID 31323276 DOI: 10.1016/j.exer.2019.107728 |
0.535 |
|
| 2019 |
Baumann BH, Shu W, Song Y, Sterling J, Kozmik Z, Littleton-Lakhal S, Dunaief JL. Liver-Specific but Not Retina-Specific Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration. The American Journal of Pathology. PMID 31287995 DOI: 10.1016/J.Ajpath.2019.05.022 |
0.868 |
|
| 2019 |
Chen Z, Jiang R, Chen M, Zheng J, Chen M, Braidy N, Liu S, Liu G, Maimaitiming Z, Shen T, Dunaief JL, Vulpe CD, Anderson GJ, Chen H. Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes. Scientific Reports. 9: 9437. PMID 31263155 DOI: 10.1038/s41598-019-46019-9 |
0.444 |
|
| 2019 |
Schultz H, Song Y, Baumann BH, Kapphahn RJ, Montezuma SR, Ferrington DA, Dunaief JL. Increased serum proteins in non-exudative AMD retinas. Experimental Eye Research. PMID 31158383 DOI: 10.1016/J.Exer.2019.05.026 |
0.393 |
|
| 2019 |
Kim BJ, Grossman M, Song D, Saludades S, Pan W, Dominguez-Perez S, Dunaief JL, Aleman TS, Ying GS, Irwin DJ. Persistent and Progressive Outer Retina Thinning in Frontotemporal Degeneration. Frontiers in Neuroscience. 13: 298. PMID 31019447 DOI: 10.3389/Fnins.2019.00298 |
0.699 |
|
| 2019 |
Ueda Y, Miwa T, Ito D, Kim H, Sato S, Gullipalli D, Zhou L, Golla M, Song D, Dunaief JL, Palmer MB, Song WC. Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation. Kidney International. PMID 30910380 DOI: 10.1016/J.Kint.2019.01.009 |
0.671 |
|
| 2019 |
Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde-Visser S, Samardzija M, Meneau I, Barben M, Karademir D, Pauzuolyte V, Boye SL, Blaser F, Ullmer C, Dunaief JL, et al. Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration. Elife. 8. PMID 30864945 DOI: 10.7554/eLife.45100 |
0.388 |
|
| 2019 |
Song D, Ueda Y, Bhuyan R, Mohammed I, Miwa T, Gullipali D, Kim H, Zhou L, Song Y, Schultz H, Bargoud A, Dunaief JL, Song WC. Complement Factor H Mutation W1206R Causes Retinal Thrombosis and Ischemic Retinopathy in Mice. The American Journal of Pathology. PMID 30711487 DOI: 10.1016/J.Ajpath.2019.01.009 |
0.752 |
|
| 2019 |
Storm T, Burgoyne T, Dunaief JL, Christensen EI, Futter C, Nielsen R. Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration. Investigative Ophthalmology & Visual Science. 60: 322-330. PMID 30665232 DOI: 10.1167/iovs.18-25667 |
0.338 |
|
| 2019 |
Badiei A, Sudharsan R, Santana E, Dunaief JL, Aguirre GD. Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina. Experimental Eye Research. PMID 30653965 DOI: 10.1016/j.exer.2019.01.007 |
0.329 |
|
| 2018 |
Shu W, Dunaief JL. Potential Treatment of Retinal Diseases with Iron Chelators. Pharmaceuticals (Basel, Switzerland). 11. PMID 30360383 DOI: 10.3390/ph11040112 |
0.615 |
|
| 2018 |
Saadane A, Petrov A, Mast N, El-Darzi N, Dao T, Alnemri A, Song Y, Dunaief JL, Pikuleva IA. Mechanisms that minimize retinal impact of apolipoprotein E absence. Journal of Lipid Research. PMID 30333155 DOI: 10.1194/Jlr.M090043 |
0.374 |
|
| 2018 |
Fuqua BK, Lu Y, Frazer DM, Darshan D, Wilkins SJ, Dunn L, Loguinov AV, Kogan SC, Matak P, Chen H, Dunaief JL, Vulpe CD, Anderson GJ. Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin. Cellular and Molecular Gastroenterology and Hepatology. 6: 405-427. PMID 30182051 DOI: 10.1016/j.jcmgh.2018.06.006 |
0.458 |
|
| 2018 |
Song D, Ying GS, Dunaief JL, Bhuyan R, Li Y, Maguire MG, Grunwald JE, Daniel E, Hagstrom S, Martin DF. ASSOCIATION BETWEEN ORAL IRON SUPPLEMENTATION AND RETINAL OR SUBRETINAL HEMORRHAGE IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENTS TRIALS. Retina (Philadelphia, Pa.). PMID 30157115 DOI: 10.1097/Iae.0000000000002295 |
0.809 |
|
| 2018 |
Song D, Mohammed I, Bhuyan R, Miwa T, Williams AL, Gullipalli D, Sato S, Song Y, Dunaief JL, Song WC. Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease. Investigative Ophthalmology & Visual Science. 59: 3405-3415. PMID 30025090 DOI: 10.1167/Iovs.18-24133 |
0.683 |
|
| 2018 |
Ueda K, Kim HJ, Zhao J, Song Y, Dunaief JL, Sparrow JR. Iron promotes oxidative cell death caused by bisretinoids of retina. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686088 DOI: 10.1073/pnas.1722601115 |
0.382 |
|
| 2018 |
Zheng J, Jiang R, Chen M, Maimaitiming Z, Wang J, Anderson GJ, Vulpe CD, Dunaief JL, Chen H. Multi-Copper Ferroxidase-Deficient Mice Have Increased Brain Iron Concentrations and Learning and Memory Deficits. The Journal of Nutrition. 148: 643-649. PMID 29659961 DOI: 10.1093/jn/nxy012 |
0.426 |
|
| 2018 |
Ueda Y, Miwa T, Gullipalli D, Sato S, Zhou L, Golla M, Kim H, Ito D, Song D, Dunaief J, Palmer M, Song W. C5aR and C5b-9 pathways drive different pathology in a murine model of aHUS and macrovascular thrombosis Molecular Immunology. 102: 223. DOI: 10.1016/J.Molimm.2018.06.234 |
0.654 |
|
| 2018 |
Song D, Ueda Y, Mohammed I, Bhuyan R, Miwa T, Gullipalli D, Zhou L, Dunaief J, Song W. Factor H mutation W1206R causes retinal thrombosis and ischemic retinopathy in mice Molecular Immunology. 102: 216. DOI: 10.1016/J.Molimm.2018.06.218 |
0.732 |
|
| 2017 |
Kim BJ, Irwin DJ, Song D, Daniel E, Leveque JD, Raquib AR, Pan W, Ying GS, Aleman TS, Dunaief JL, Grossman M. Optical coherence tomography identifies outer retina thinning in frontotemporal degeneration. Neurology. PMID 28887373 DOI: 10.1212/Wnl.0000000000004500 |
0.69 |
|
| 2017 |
Baumann B, Sterling J, Song Y, Song D, Fruttiger M, Gillies M, Shen W, Dunaief JL. Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation. Investigative Ophthalmology & Visual Science. 58: 4223-4234. PMID 28846772 DOI: 10.1167/Iovs.17-21743 |
0.869 |
|
| 2017 |
Qi S, Wang C, Song D, Song Y, Dunaief JL. Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina. Molecular Vision. 23: 171-178. PMID 28458506 |
0.712 |
|
| 2017 |
Song D, Sulewski ME, Wang C, Song J, Bhuyan R, Sterling J, Clark E, Song WC, Dunaief JL. Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration. Molecular Vision. 23: 210-218. PMID 28442885 |
0.8 |
|
| 2017 |
Ueda Y, Mohammed I, Song D, Gullipalli D, Zhou L, Sato S, Wang Y, Gupta S, Cheng Z, Wang H, Bao J, Mao Y, Brass L, Zheng XL, Miwa T, ... ... Dunaief J, et al. Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation. Blood. PMID 28057640 DOI: 10.1182/Blood-2016-07-728253 |
0.69 |
|
| 2017 |
Sterling J, Guttha S, Song Y, Song D, Hadziahmetovic M, Dunaief JL. Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. Experimental Eye Research. PMID 28057442 DOI: 10.1016/J.Exer.2016.12.008 |
0.875 |
|
| 2016 |
Jiang B, Liu G, Zheng J, Chen M, Maimaitiming Z, Chen M, Liu S, Jiang R, Fuqua BK, Dunaief JL, Vulpe CD, Anderson GJ, Wang H, Chen H. Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney. Scientific Reports. 6: 39470. PMID 27991585 DOI: 10.1038/srep39470 |
0.381 |
|
| 2016 |
Song D, Wilson B, Zhao L, Bhuyan R, Bandyopadhyay M, Lyubarsky A, Yu C, Li Y, Kanu L, Miwa T, Song WC, Finnemann SC, Rohrer B, Dunaief JL. Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration. Plos One. 11: e0166348. PMID 27893831 DOI: 10.1371/Journal.Pone.0166348 |
0.75 |
|
| 2016 |
Song D, Kanu LN, Li Y, Kelly KL, Bhuyan RK, Aleman T, Morgan JI, Dunaief JL. AMD-like retinopathy associated with intravenous iron. Experimental Eye Research. PMID 27565570 DOI: 10.1016/J.Exer.2016.08.008 |
0.833 |
|
| 2016 |
Oh S, Mao Y, Yang Z, Nace A, Zheng Y, Beer J, Dunaief J, Cotsarelis G. 675 Hair loss in hephaestin knockout mice is associated with iron deficiency Journal of Investigative Dermatology. 136: S120. DOI: 10.1016/J.Jid.2016.02.717 |
0.432 |
|
| 2016 |
Mohammed I, Song D, Miwa T, Wlliams AL, Gullipali D, Sato S, Dunaief JL, Song W. Subretinal and sub-RPE deposition in mice with combined factor H mutation and properdin deficiency Immunobiology. 221: 1190. DOI: 10.1016/J.Imbio.2016.06.145 |
0.676 |
|
| 2015 |
Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL. Mice with hepcidin-resistant ferroportin accumulate iron in the retina. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26506980 DOI: 10.1096/Fj.15-276758 |
0.861 |
|
| 2015 |
Song D, Song J, Wang C, Li Y, Dunaief JL. Berberine protects against light-induced photoreceptor degeneration in the mouse retina. Experimental Eye Research. PMID 26475979 DOI: 10.1016/J.Exer.2015.10.005 |
0.756 |
|
| 2015 |
Bhoiwala DL, Dunaief JL. Retinal abnormalities in β-thalassemia major. Survey of Ophthalmology. PMID 26325202 DOI: 10.1016/j.survophthal.2015.08.005 |
0.487 |
|
| 2015 |
Zhao L, Hadziahmetovic M, Wang C, Xu X, Song Y, Jinnah HA, Wodzinska J, Iacovelli J, Wolkow N, Krajacic P, Cwanger Weissberger A, Connelly J, Spino M, Lee MK, Connor J, ... ... Dunaief JL, et al. Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone. Journal of Neurochemistry. PMID 26303407 DOI: 10.1111/Jnc.13292 |
0.847 |
|
| 2015 |
Bhoiwala DL, Song Y, Cwanger A, Clark E, Zhao LL, Wang C, Li Y, Song D, Dunaief JL. CD1 Mouse Retina Is Shielded From Iron Overload Caused by a High Iron Diet. Investigative Ophthalmology & Visual Science. 56: 5344-52. PMID 26275132 DOI: 10.1167/Iovs.15-17026 |
0.811 |
|
| 2015 |
Yao J, Jia L, Khan N, Lin C, Mitter SK, Boulton ME, Dunaief JL, Klionsky DJ, Guan JL, Thompson DA, Zacks DN. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 11: 939-53. PMID 26075877 DOI: 10.1080/15548627.2015.1041699 |
0.402 |
|
| 2015 |
Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, ... ... Dunaief JL, et al. Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. Cell Reports. 11: 1686-93. PMID 26074074 DOI: 10.1016/J.Celrep.2015.05.023 |
0.487 |
|
| 2015 |
Li Y, Song D, Song Y, Zhao L, Wolkow N, Tobias JW, Song W, Dunaief JL. Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium. The Journal of Biological Chemistry. 290: 11918-34. PMID 25802332 DOI: 10.1074/Jbc.M115.645903 |
0.845 |
|
| 2015 |
Jiang R, Hua C, Wan Y, Jiang B, Hu H, Zheng J, Fuqua BK, Dunaief JL, Anderson GJ, David S, Vulpe CD, Chen H. Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain. The Journal of Nutrition. 145: 1003-9. PMID 25788583 DOI: 10.3945/jn.114.207316 |
0.404 |
|
| 2014 |
Guo LY, Alekseev O, Li Y, Song Y, Dunaief JL. Iron increases APP translation and amyloid-beta production in the retina. Experimental Eye Research. 129: 31-7. PMID 25456519 DOI: 10.1016/j.exer.2014.10.012 |
0.491 |
|
| 2014 |
Wolkow N, Li Y, Maminishkis A, Song Y, Alekseev O, Iacovelli J, Song D, Lee JC, Dunaief JL. Iron upregulates melanogenesis in cultured retinal pigment epithelial cells. Experimental Eye Research. 128: 92-101. PMID 25277027 DOI: 10.1016/J.Exer.2014.09.010 |
0.86 |
|
| 2014 |
Zhao L, Li Y, Song D, Song Y, Theurl M, Wang C, Cwanger A, Su G, Dunaief JL. A high serum iron level causes mouse retinal iron accumulation despite an intact blood-retinal barrier. The American Journal of Pathology. 184: 2862-7. PMID 25174877 DOI: 10.1016/J.Ajpath.2014.07.008 |
0.835 |
|
| 2014 |
Zhao L, Wang C, Song D, Li Y, Song Y, Su G, Dunaief JL. Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina. Investigative Ophthalmology & Visual Science. 55: 5979-88. PMID 25146987 DOI: 10.1167/Iovs.14-15025 |
0.812 |
|
| 2014 |
Song D, Grieco S, Li Y, Hunter A, Chu S, Zhao L, Song Y, DeAngelis RA, Shi LY, Liu Q, Pierce EA, Nishina PM, Lambris JD, Dunaief JL. A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration. The American Journal of Pathology. 184: 2721-9. PMID 25088982 DOI: 10.1016/J.Ajpath.2014.06.010 |
0.806 |
|
| 2014 |
Song D, Zhao L, Li Y, Hadziahmetovic M, Song Y, Connelly J, Spino M, Dunaief JL. The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice. Investigative Ophthalmology & Visual Science. 55: 4525-32. PMID 24970260 DOI: 10.1167/Iovs.14-14568 |
0.837 |
|
| 2014 |
Fuqua BK, Lu Y, Darshan D, Frazer DM, Wilkins SJ, Wolkow N, Bell AG, Hsu J, Yu CC, Chen H, Dunaief JL, Anderson GJ, Vulpe CD. The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice. Plos One. 9: e98792. PMID 24896847 DOI: 10.1371/Journal.Pone.0098792 |
0.736 |
|
| 2014 |
He L, Marioutina M, Dunaief JL, Marneros AG. Age- and gene-dosage-dependent cre-induced abnormalities in the retinal pigment epithelium. The American Journal of Pathology. 184: 1660-7. PMID 24854863 DOI: 10.1016/j.ajpath.2014.02.007 |
0.307 |
|
| 2014 |
Masuda T, Wahlin K, Wan J, Hu J, Maruotti J, Yang X, Iacovelli J, Wolkow N, Kist R, Dunaief JL, Qian J, Zack DJ, Esumi N. Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium. The Journal of Biological Chemistry. 289: 12908-21. PMID 24634209 DOI: 10.1074/Jbc.M114.556738 |
0.795 |
|
| 2014 |
Dunaief D, Cwanger A, Dunaief JL. Iron-Induced Retinal Damage Handbook of Nutrition, Diet and the Eye. 619-626. DOI: 10.1016/B978-0-12-401717-7.00063-0 |
0.58 |
|
| 2013 |
Song D, Dunaief JL. Retinal iron homeostasis in health and disease. Frontiers in Aging Neuroscience. 5: 24. PMID 23825457 DOI: 10.3389/Fnagi.2013.00024 |
0.84 |
|
| 2013 |
Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF. Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3582-7. PMID 23426685 DOI: 10.1523/Jneurosci.1497-12.2013 |
0.52 |
|
| 2012 |
Hadziahmetovic M, Pajic M, Grieco S, Song Y, Song D, Li Y, Cwanger A, Iacovelli J, Chu S, Ying GS, Connelly J, Spino M, Dunaief JL. The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms. Translational Vision Science & Technology. 1: 2. PMID 24049709 DOI: 10.1167/Tvst.1.3.2 |
0.865 |
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| 2012 |
Hadziahmetovic M, Pajic M, Grieco S, Song Y, Song D, Li Y, Cwanger A, Iacovelli J, Chu S, Ying GS, Connelly J, Spino M, Dunaief JL. The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms. Translational Vision Science & Technology. 1: 7. PMID 24049707 DOI: 10.1167/tvst.1.2.7 |
0.865 |
|
| 2012 |
Hadziahmetovic M, Kumar U, Song Y, Grieco S, Song D, Li Y, Tobias JW, Dunaief JL. Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE. Investigative Ophthalmology & Visual Science. 53: 5231-41. PMID 22736611 DOI: 10.1167/Iovs.12-10204 |
0.828 |
|
| 2012 |
Song D, Song Y, Hadziahmetovic M, Zhong Y, Dunaief JL. Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina. Free Radical Biology & Medicine. 53: 64-71. PMID 22579919 DOI: 10.1016/J.Freeradbiomed.2012.04.020 |
0.763 |
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| 2012 |
Wolkow N, Song D, Song Y, Chu S, Hadziahmetovic M, Lee JC, Iacovelli J, Grieco S, Dunaief JL. Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium. The American Journal of Pathology. 180: 1614-24. PMID 22342521 DOI: 10.1016/J.Ajpath.2011.12.041 |
0.87 |
|
| 2011 |
Wolkow N, Song Y, Wu TD, Qian J, Guerquin-Kern JL, Dunaief JL. Aceruloplasminemia: retinal histopathologic manifestations and iron-mediated melanosome degradation. Archives of Ophthalmology (Chicago, Ill. : 1960). 129: 1466-74. PMID 22084216 DOI: 10.1001/Archophthalmol.2011.309 |
0.802 |
|
| 2011 |
Leed MG, Wolkow N, Pham DM, Daniel CL, Dunaief JL, Franz KJ. Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress. Journal of Inorganic Biochemistry. 105: 1161-72. PMID 21708101 DOI: 10.1016/J.Jinorgbio.2011.05.023 |
0.639 |
|
| 2011 |
Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Kautz L, Roth MP, Dunaief JL. Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration. The American Journal of Pathology. 179: 335-48. PMID 21703414 DOI: 10.1016/J.Ajpath.2011.03.033 |
0.885 |
|
| 2011 |
Dunaief JL. Ironing out neurodegeneration: iron chelation for neuroprotection. Free Radical Biology & Medicine. 51: 1480-1. PMID 21616141 DOI: 10.1016/j.freeradbiomed.2011.05.009 |
0.47 |
|
| 2011 |
Iacovelli J, Zhao C, Wolkow N, Veldman P, Gollomp K, Ojha P, Lukinova N, King A, Feiner L, Esumi N, Zack DJ, Pierce EA, Vollrath D, Dunaief JL. Generation of Cre transgenic mice with postnatal RPE-specific ocular expression. Investigative Ophthalmology & Visual Science. 52: 1378-83. PMID 21212186 DOI: 10.1167/Iovs.10-6347 |
0.789 |
|
| 2011 |
Zhao C, Yasumura D, Li X, Matthes M, Lloyd M, Nielsen G, Ahern K, Snyder M, Bok D, Dunaief JL, LaVail MM, Vollrath D. mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice. The Journal of Clinical Investigation. 121: 369-83. PMID 21135502 DOI: 10.1172/Jci44303 |
0.404 |
|
| 2011 |
Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Grieco S, Lee J, Lyubarsky A, Pratico D, Connelly J, Spino M, Harris ZL, Dunaief JL. The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration. Investigative Ophthalmology & Visual Science. 52: 959-68. PMID 21051716 DOI: 10.1167/Iovs.10-6207 |
0.876 |
|
| 2011 |
Hadziahmetovic M, Song Y, Ponnuru P, Iacovelli J, Hunter A, Haddad N, Beard J, Connor JR, Vaulont S, Dunaief JL. Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. Investigative Ophthalmology & Visual Science. 52: 109-18. PMID 20811044 DOI: 10.1167/Iovs.10-6113 |
0.87 |
|
| 2009 |
Iacovelli J, Mlodnicka AE, Veldman P, Ying GS, Dunaief JL, Schumacher A. Brain and retinal ferroportin 1 dysregulation in polycythaemia mice. Brain Research. 1289: 85-95. PMID 19596281 DOI: 10.1016/J.Brainres.2009.06.098 |
0.833 |
|
| 2009 |
Hahn P, Song Y, Ying GS, He X, Beard J, Dunaief JL. Age-dependent and gender-specific changes in mouse tissue iron by strain. Experimental Gerontology. 44: 594-600. PMID 19563877 DOI: 10.1016/J.Exger.2009.06.006 |
0.654 |
|
| 2009 |
Lukinova N, Iacovelli J, Dentchev T, Wolkow N, Hunter A, Amado D, Ying GS, Sparrow JR, Dunaief JL. Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli. Investigative Ophthalmology & Visual Science. 50: 1440-7. PMID 19182262 DOI: 10.1167/Iovs.08-2545 |
0.849 |
|
| 2009 |
Loh A, Hadziahmetovic M, Dunaief JL. Iron homeostasis and eye disease. Biochimica Et Biophysica Acta. 1790: 637-49. PMID 19059309 DOI: 10.1016/j.bbagen.2008.11.001 |
0.518 |
|
| 2008 |
Charkoudian LK, Dentchev T, Lukinova N, Wolkow N, Dunaief JL, Franz KJ. Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide. Journal of Inorganic Biochemistry. 102: 2130-5. PMID 18835041 DOI: 10.1016/J.Jinorgbio.2008.08.001 |
0.763 |
|
| 2008 |
Bhisitkul RB, Winn BJ, Lee OT, Wong J, Pereira Dde S, Porco TC, He X, Hahn P, Dunaief JL. Neuroprotective effect of intravitreal triamcinolone acetonide against photoreceptor apoptosis in a rabbit model of subretinal hemorrhage. Investigative Ophthalmology & Visual Science. 49: 4071-7. PMID 18421081 DOI: 10.1167/Iovs.08-1892 |
0.667 |
|
| 2008 |
Hadziahmetovic M, Dentchev T, Song Y, Haddad N, He X, Hahn P, Pratico D, Wen R, Harris ZL, Lambris JD, Beard J, Dunaief JL. Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. Investigative Ophthalmology & Visual Science. 49: 2728-36. PMID 18326691 DOI: 10.1167/Iovs.07-1472 |
0.711 |
|
| 2007 |
Wong RW, Richa DC, Hahn P, Green WR, Dunaief JL. Iron toxicity as a potential factor in AMD. Retina (Philadelphia, Pa.). 27: 997-1003. PMID 18040235 DOI: 10.1097/Iae.0B013E318074C290 |
0.734 |
|
| 2007 |
He X, Hahn P, Iacovelli J, Wong R, King C, Bhisitkul R, Massaro-Giordano M, Dunaief JL. Iron homeostasis and toxicity in retinal degeneration. Progress in Retinal and Eye Research. 26: 649-73. PMID 17921041 DOI: 10.1016/J.Preteyeres.2007.07.004 |
0.871 |
|
| 2007 |
Dentchev T, Yao Y, Pratico D, Dunaief J. Isoprostane F2alpha-VI, a new marker of oxidative stress, increases following light damage to the mouse retina. Molecular Vision. 13: 190-5. PMID 17327824 |
0.306 |
|
| 2006 |
Hahn P, Ying GS, Beard J, Dunaief JL. Iron levels in human retina: sex difference and increase with age. Neuroreport. 17: 1803-6. PMID 17164668 DOI: 10.1097/Wnr.0B013E3280107776 |
0.67 |
|
| 2006 |
Dunaief JL. Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture. Investigative Ophthalmology & Visual Science. 47: 4660-4. PMID 17065470 DOI: 10.1167/iovs.06-0568 |
0.623 |
|
| 2006 |
Krajacic P, Qian Y, Hahn P, Dentchev T, Lukinova N, Dunaief JL. Retinal localization and copper-dependent relocalization of the Wilson and Menkes disease proteins. Investigative Ophthalmology & Visual Science. 47: 3129-34. PMID 16799059 DOI: 10.1167/Iovs.05-1601 |
0.564 |
|
| 2006 |
Chowers I, Wong R, Dentchev T, Farkas RH, Iacovelli J, Gunatilaka TL, Medeiros NE, Presley JB, Campochiaro PA, Curcio CA, Dunaief JL, Zack DJ. The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration. Investigative Ophthalmology & Visual Science. 47: 2135-40. PMID 16639025 DOI: 10.1167/Iovs.05-1135 |
0.856 |
|
| 2005 |
Dentchev T, Hahn P, Dunaief JL. Strong labeling for iron and the iron-handling proteins ferritin and ferroportin in the photoreceptor layer in age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 123: 1745-6. PMID 16344450 DOI: 10.1001/Archopht.123.12.1745 |
0.662 |
|
| 2005 |
Hahn P, Lindsten T, Tolentino M, Thompson CB, Bennett J, Dunaief JL. Persistent fetal ocular vasculature in mice deficient in bax and bak. Archives of Ophthalmology (Chicago, Ill. : 1960). 123: 797-802. PMID 15955981 DOI: 10.1001/Archopht.123.6.797 |
0.496 |
|
| 2005 |
Dunaief JL, Richa C, Franks EP, Schultze RL, Aleman TS, Schenck JF, Zimmerman EA, Brooks DG. Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload. Ophthalmology. 112: 1062-5. PMID 15882908 DOI: 10.1016/j.ophtha.2004.12.029 |
0.594 |
|
| 2004 |
Rex TS, Tsui I, Hahn P, Maguire AM, Duan D, Bennett J, Dunaief JL. Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress. Human Gene Therapy. 15: 960-7. PMID 15585111 DOI: 10.1089/Hum.2004.15.960 |
0.511 |
|
| 2004 |
Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, Dunaief JL. Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 101: 13850-5. PMID 15365174 DOI: 10.1073/Pnas.0405146101 |
0.746 |
|
| 2004 |
Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL. Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. Molecular Vision. 10: 598-607. PMID 15354085 |
0.728 |
|
| 2004 |
Chen L, Wu W, Dentchev T, Wong R, Dunaief JL. Increased metallothionein in light damaged mouse retinas. Experimental Eye Research. 79: 287-93. PMID 15325575 DOI: 10.1016/j.exer.2004.05.004 |
0.374 |
|
| 2004 |
Chen L, Wu W, Dentchev T, Zeng Y, Wang J, Tsui I, Tobias JW, Bennett J, Baldwin D, Dunaief JL. Light damage induced changes in mouse retinal gene expression. Experimental Eye Research. 79: 239-47. PMID 15325571 DOI: 10.1016/J.Exer.2004.05.002 |
0.321 |
|
| 2004 |
Hahn P, Lindsten T, Lyubarsky A, Ying GS, Pugh EN, Thompson CB, Dunaief JL. Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. Cell Death and Differentiation. 11: 1192-7. PMID 15272317 DOI: 10.1038/Sj.Cdd.4401486 |
0.537 |
|
| 2004 |
King A, Gottlieb E, Brooks DG, Murphy MP, Dunaief JL. Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochemistry and Photobiology. 79: 470-5. PMID 15191057 DOI: 10.1562/LE-03-17.1 |
0.315 |
|
| 2003 |
Hahn P, Milam AH, Dunaief JL. Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane. Archives of Ophthalmology (Chicago, Ill. : 1960). 121: 1099-105. PMID 12912686 DOI: 10.1001/Archopht.121.8.1099 |
0.7 |
|
| 2003 |
Hahn P, Lindsten T, Ying GS, Bennett J, Milam AH, Thompson CB, Dunaief JL. Proapoptotic bcl-2 family members, Bax and Bak, are essential for developmental photoreceptor apoptosis. Investigative Ophthalmology & Visual Science. 44: 3598-605. PMID 12882813 DOI: 10.1167/Iovs.02-1113 |
0.568 |
|
| 2003 |
Chen L, Dentchev T, Wong R, Hahn P, Wen R, Bennett J, Dunaief JL. Increased expression of ceruloplasmin in the retina following photic injury. Molecular Vision. 9: 151-8. PMID 12724641 |
0.59 |
|
| 2002 |
Dunaief JL, Dentchev T, Ying GS, Milam AH. The role of apoptosis in age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 120: 1435-42. PMID 12427055 DOI: 10.1001/Archopht.120.11.1435 |
0.352 |
|
| 2001 |
Dunaief JL, Conway J, Rigamonti D, Goldberg MF. Retinal venous telangiectasia and anastomoses with cerebellar venous and cavernous malformation. Retina (Philadelphia, Pa.). 21: 262-5. PMID 11421019 |
0.326 |
|
| 1996 |
Strober BE, Dunaief JL, Guha, Goff SP. Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins. Molecular and Cellular Biology. 16: 1576-83. PMID 8657132 |
0.376 |
|
| 1995 |
Dunaief JL, Kwun RC, Bhardwaj N, Lopez R, Gouras P, Goff SP. Retroviral gene transfer into retinal pigment epithelial cells followed by transplantation into rat retina. Human Gene Therapy. 6: 1225-9. PMID 8527481 DOI: 10.1089/hum.1995.6.9-1225 |
0.482 |
|
| 1994 |
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell. 79: 119-30. PMID 7923370 DOI: 10.1016/0092-8674(94)90405-7 |
0.591 |
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