Year |
Citation |
Score |
2023 |
Vandiver AR, Hoang AN, Herbst A, Lee CC, Aiken JM, McKenzie D, Teitell MA, Timp W, Wanagat J. Nanopore sequencing identifies a higher frequency and expanded spectrum of mitochondrial DNA deletion mutations in human aging. Aging Cell. e13842. PMID 37132288 DOI: 10.1111/acel.13842 |
0.822 |
|
2022 |
Herbst A, Choi S, Hoang AN, Kim C, Martinez Moreno D, McKenzie D, Aiken JM, Wanagat J. Remdesivir does not affect mitochondrial DNA copy number or deletion mutation frequency in aged male rats: A short report. Plos One. 17: e0271850. PMID 36288327 DOI: 10.1371/journal.pone.0271850 |
0.819 |
|
2022 |
Herbst A, Aiken JM, Kim C, Gushue D, McKenzie D, Moore TM, Zhou J, Hoang AN, Choi S, Wanagat J. Age- and time-dependent mitochondrial genotoxic and myopathic effects of beta-guanidinopropionic acid, a creatine analog, on rodent skeletal muscles. Geroscience. PMID 36178599 DOI: 10.1007/s11357-022-00667-4 |
0.838 |
|
2022 |
Herbst A, Wohlgemuth S, Yang J, Castle AR, Moreno DM, Otero A, Aiken JM, Westaway D, McKenzie D. Susceptibility of Beavers to Chronic Wasting Disease. Biology. 11. PMID 35625395 DOI: 10.3390/biology11050667 |
0.648 |
|
2022 |
O'Hara E, Herbst A, Kommadath A, Aiken JM, McKenzie D, Goodarzi N, Skinner P, Stothard P. Neural transcriptomic signature of chronic wasting disease in white-tailed deer. Bmc Genomics. 23: 69. PMID 35062879 DOI: 10.1186/s12864-022-08306-0 |
0.622 |
|
2021 |
Herbst A, Hoang A, Kim C, Aiken J, McKenzie D, Goldwater D, Wanagat J. Metformin treatment in old rats and effects on mitochondrial integrity. Rejuvenation Research. PMID 34779265 DOI: 10.1089/rej.2021.0052 |
0.81 |
|
2021 |
Herbst A, Prior SJ, Lee CC, Aiken JM, McKenzie D, Hoang A, Liu N, Chen X, Xun P, Allison DB, Wanagat J. Skeletal muscle mitochondrial DNA copy number and mitochondrial DNA deletion mutation frequency as predictors of physical performance in older men and women. Geroscience. PMID 33740224 DOI: 10.1007/s11357-021-00351-z |
0.825 |
|
2020 |
Herbst A, Lee CC, Vandiver AR, Aiken JM, McKenzie D, Hoang A, Allison D, Liu N, Wanagat J. Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle. Aging Clinical and Experimental Research. PMID 32965609 DOI: 10.1007/s40520-020-01698-7 |
0.826 |
|
2020 |
Herbst A, Aiken JM, McKenzie D, Wanagat J. Comment on: "Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging. 2020, , 197". Cells. 9. PMID 32751058 DOI: 10.3390/Cells9081796 |
0.842 |
|
2020 |
Duque Velásquez C, Kim C, Haldiman T, Kim C, Herbst A, Aiken JM, Safar JG, McKenzie D. Chronic wasting disease (CWD) prion strains evolve via adaptive diversification of conformers in hosts expressing prion protein polymorphisms. The Journal of Biological Chemistry. PMID 32111742 DOI: 10.1074/Jbc.Ra120.012546 |
0.662 |
|
2019 |
Herbst A, Hoang AN, Woo W, McKenzie D, Aiken JM, Miller RA, Allison DB, Liu N, Wanagat J. Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice. Mechanisms of Ageing and Development. 111126. PMID 31381889 DOI: 10.1016/J.Mad.2019.111126 |
0.826 |
|
2019 |
Otero A, Duque Velásquez C, Johnson C, Herbst A, Bolea R, Badiola JJ, Aiken J, McKenzie D. Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP deposition in orally infected white-tailed deer. Bmc Veterinary Research. 15: 50. PMID 30717795 DOI: 10.1186/S12917-019-1794-Z |
0.662 |
|
2018 |
Gushue D, Herbst A, Sim V, McKenzie D, Aiken JM. 14-3-3 and Enolase Abundances in the CSF of Prion Diseased Rats. Prion. PMID 30149773 DOI: 10.1080/19336896.2018.1513317 |
0.637 |
|
2018 |
Bielas J, Herbst A, Widjaja K, Hui J, Aiken JM, McKenzie D, Miller RA, Brooks S, Wanagat J. Long term rapamycin treatment improves mitochondrial DNA quality in aging mice. Experimental Gerontology. PMID 29486228 DOI: 10.1016/J.Exger.2018.02.021 |
0.83 |
|
2017 |
Barton GP, de Lange WJ, Ralphe JC, Aiken J, Diffee G. Linking metabolic and contractile dysfunction in aged cardiac myocytes. Physiological Reports. 5. PMID 29084842 DOI: 10.14814/Phy2.13485 |
0.369 |
|
2017 |
Wei L, Gregorich ZR, Lin Z, Cai W, Jin Y, McKiernan SH, McIlwain S, Aiken JM, Moss RL, Diffee GM, Ge Y. Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications in Skeletal Muscles Identified by Top-down Proteomics. Molecular & Cellular Proteomics : McP. PMID 29046390 DOI: 10.1074/Mcp.Ra117.000124 |
0.469 |
|
2017 |
Herbst A, Velásquez CD, Triscott E, Aiken JM, McKenzie D. Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion. Emerging Infectious Diseases. 23: 1598-1600. PMID 28820384 DOI: 10.3201/Eid2309.161474 |
0.651 |
|
2017 |
Herbst A, Widjaja K, Nguy B, Lushaj EB, Moore TM, Hevener AL, McKenzie D, Aiken JM, Wanagat J. Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28460005 DOI: 10.1093/Gerona/Glx058 |
0.854 |
|
2016 |
Barton GP, Sepe JJ, McKiernan SH, Aiken JM, Diffee GM. Mitochondrial and Metabolic Gene Expression in the Aged Rat Heart. Frontiers in Physiology. 7: 352. PMID 27601998 DOI: 10.3389/Fphys.2016.00352 |
0.375 |
|
2016 |
Herbst A, Wanagat J, Cheema N, Widjaja K, McKenzie D, Aiken JM. Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age. Aging Cell. PMID 27561813 DOI: 10.1111/Acel.12520 |
0.859 |
|
2016 |
Gregorich ZR, Peng Y, Cai W, Jin Y, Wei L, Chen AJ, McKiernan SH, Aiken JM, Moss RL, Diffee GM, Ge Y. Top-down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light Chain Phosphorylation that Contributes to Sarcopenic Muscle Dysfunction. Journal of Proteome Research. PMID 27362462 DOI: 10.1021/Acs.Jproteome.6B00244 |
0.484 |
|
2015 |
Duque Velásquez C, Kim C, Herbst A, Daude N, Garza MC, Wille H, Aiken J, McKenzie D. Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains. Journal of Virology. PMID 26423950 DOI: 10.1128/Jvi.02010-15 |
0.664 |
|
2015 |
Cheema N, Herbst A, McKenzie D, Aiken JM. Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities. Aging Cell. PMID 26365892 DOI: 10.1111/Acel.12399 |
0.801 |
|
2015 |
Herbst A, Ness A, Johnson CJ, McKenzie D, Aiken JM. Transcriptomic responses to prion disease in rats. Bmc Genomics. 16: 682. PMID 26341492 DOI: 10.1186/S12864-015-1884-7 |
0.665 |
|
2015 |
Barton G, McKiernan S, Aiken J, Diffee G. Metabolic and Mitochondrial Gene Expression Changes in the Aging Heart The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.1047.5 |
0.348 |
|
2014 |
Herbst A, Aiken JM, McKenzie D. Replication of prions in differentiated muscle cells. Prion. 8. PMID 24518642 DOI: 10.4161/Pri.27890 |
0.692 |
|
2013 |
Herbst A, Banser P, Velasquez CD, Mays CE, Sim VL, Westaway D, Aiken JM, McKenzie D. Infectious prions accumulate to high levels in non proliferative C2C12 myotubes. Plos Pathogens. 9: e1003755. PMID 24244171 DOI: 10.1371/Journal.Ppat.1003755 |
0.695 |
|
2013 |
Herbst A, Johnson CJ, Hynes K, McKenzie D, Aiken JM. Mitochondrial biogenesis drives a vicious cycle of metabolic insufficiency and mitochondrial DNA deletion mutation accumulation in aged rat skeletal muscle fibers. Plos One. 8: e59006. PMID 23516592 DOI: 10.1371/Journal.Pone.0059006 |
0.805 |
|
2012 |
McKiernan SH, Colman RJ, Aiken E, Evans TD, Beasley TM, Aiken JM, Weindruch R, Anderson RM. Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys. Experimental Gerontology. 47: 229-36. PMID 22226624 DOI: 10.1016/J.Exger.2011.12.009 |
0.538 |
|
2011 |
Wei X, Herbst A, Ma D, Aiken J, Li L. A quantitative proteomic approach to prion disease biomarker research: Delving into the glycoproteome Journal of Proteome Research. 10: 2687-2702. PMID 21469646 DOI: 10.1021/Pr2000495 |
0.647 |
|
2011 |
Moody LR, Herbst AJ, Aiken JM. Upregulation of interferon-gamma-induced genes during prion infection. Journal of Toxicology and Environmental Health. Part A. 74: 146-53. PMID 21218343 DOI: 10.1080/15287394.2011.529064 |
0.753 |
|
2011 |
McKiernan SH, Colman RJ, Lopez M, Beasley TM, Aiken JM, Anderson RM, Weindruch R. Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle. Experimental Gerontology. 46: 23-9. PMID 20883771 DOI: 10.1016/J.Exger.2010.09.011 |
0.787 |
|
2009 |
Moody LR, Herbst AJ, Yoo HS, Vanderloo JP, Aiken JM. Comparative prion disease gene expression profiling using the prion disease mimetic, cuprizone. Prion. 3: 99-109. PMID 19535908 DOI: 10.4161/Pri.3.2.9059 |
0.765 |
|
2009 |
Herbst A, McIlwain S, Schmidt JJ, Aiken JM, Page CD, Li L. Prion disease diagnosis by proteomic profiling. Journal of Proteome Research. 8: 1030-6. PMID 19133784 DOI: 10.1021/Pr800832S |
0.652 |
|
2009 |
McKiernan SH, Colman R, Lopez M, Beasley TM, Weindruch R, Aiken JM. Longitudinal analysis of early stage sarcopenia in aging rhesus monkeys. Experimental Gerontology. 44: 170-6. PMID 18983905 DOI: 10.1016/J.Exger.2008.09.014 |
0.778 |
|
2008 |
Lushaj EB, Johnson JK, McKenzie D, Aiken JM. Sarcopenia accelerates at advanced ages in Fisher 344xBrown Norway rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 921-7. PMID 18840796 DOI: 10.1093/Gerona/63.9.921 |
0.534 |
|
2007 |
Herbst A, Pak JW, McKenzie D, Bua E, Bassiouni M, Aiken JM. Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 235-45. PMID 17389720 DOI: 10.1093/Gerona/62.3.235 |
0.844 |
|
2007 |
McKiernan SH, Tuen VC, Baldwin K, Wanagat J, Djamali A, Aiken JM. Adult-onset calorie restriction delays the accumulation of mitochondrial enzyme abnormalities in aging rat kidney tubular epithelial cells. American Journal of Physiology. Renal Physiology. 292: F1751-60. PMID 17344189 DOI: 10.1152/Ajprenal.00307.2006 |
0.736 |
|
2006 |
Bua E, Johnson J, Herbst A, Delong B, McKenzie D, Salamat S, Aiken JM. Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers. American Journal of Human Genetics. 79: 469-80. PMID 16909385 DOI: 10.1086/507132 |
0.85 |
|
2006 |
Hacker TA, McKiernan SH, Douglas PS, Wanagat J, Aiken JM. Age-related changes in cardiac structure and function in Fischer 344 x Brown Norway hybrid rats. American Journal of Physiology. Heart and Circulatory Physiology. 290: H304-11. PMID 16143657 DOI: 10.1152/Ajpheart.00290.2005 |
0.677 |
|
2006 |
Schramm PT, Johnson CJ, Mathews NE, McKenzie D, Aiken JM, Pedersen JA. Potential role of soil in the transmission of prion disease Reviews in Mineralogy and Geochemistry. 64: 135-152. DOI: 10.2138/Rmg.2006.64.5 |
0.315 |
|
2005 |
Colman RJ, McKiernan SH, Aiken JM, Weindruch R. Muscle mass loss in Rhesus monkeys: age of onset. Experimental Gerontology. 40: 573-81. PMID 15985353 DOI: 10.1016/J.Exger.2005.05.001 |
0.443 |
|
2005 |
Pak JW, Vang F, Johnson C, McKenzie D, Aiken JM. MtDNA point mutations are associated with deletion mutations in aged rat. Experimental Gerontology. 40: 209-18. PMID 15763398 DOI: 10.1016/J.Exger.2004.12.005 |
0.458 |
|
2004 |
Gokey NG, Cao Z, Pak JW, Lee D, McKiernan SH, McKenzie D, Weindruch R, Aiken JM. Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys. Aging Cell. 3: 319-26. PMID 15379855 DOI: 10.1111/J.1474-9728.2004.00122.X |
0.525 |
|
2004 |
Pak JW, Aiken JM. Low levels of mtDNA deletion mutations in ETS normal fibers from aged rats. Annals of the New York Academy of Sciences. 1019: 289-93. PMID 15247031 DOI: 10.1196/Annals.1297.049 |
0.46 |
|
2004 |
McKiernan SH, Bua E, McGorray J, Aiken J. Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 580-1. PMID 14734642 DOI: 10.1096/Fj.03-0667Fje |
0.836 |
|
2004 |
Bua E, McKiernan SH, Aiken JM. Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 582-4. PMID 14734641 DOI: 10.1096/Fj.03-0668Fje |
0.831 |
|
2003 |
Pak JW, Herbst A, Bua E, Gokey N, McKenzie D, Aiken JM. Rebuttal to Jacobs: the mitochondrial theory of aging: alive and well. Aging Cell. 2: 9-10. PMID 12882329 DOI: 10.1046/J.1474-9728.2003.00037.X |
0.829 |
|
2003 |
Pak JW, Herbst A, Bua E, Gokey N, McKenzie D, Aiken JM. Mitochondrial DNA mutations as a fundamental mechanism in physiological declines associated with aging. Aging Cell. 2: 1-7. PMID 12882328 DOI: 10.1046/J.1474-9728.2003.00034.X |
0.822 |
|
2002 |
Bua EA, McKiernan SH, Wanagat J, McKenzie D, Aiken JM. Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 2617-24. PMID 12015381 DOI: 10.1152/Japplphysiol.01102.2001 |
0.83 |
|
2002 |
McKenzie D, Bua E, McKiernan S, Cao Z, Aiken JM. Mitochondrial DNA deletion mutations: a causal role in sarcopenia. European Journal of Biochemistry / Febs. 269: 2010-5. PMID 11985577 DOI: 10.1046/J.1432-1033.2002.02867.X |
0.852 |
|
2002 |
Aiken J, Bua E, Cao Z, Lopez M, Wanagat J, McKenzie D, McKiernan S. Mitochondrial DNA deletion mutations and sarcopenia. Annals of the New York Academy of Sciences. 959: 412-23. PMID 11976214 DOI: 10.1111/J.1749-6632.2002.Tb02111.X |
0.836 |
|
2002 |
Wanagat J, Wolff MR, Aiken JM. Age-associated changes in function, structure and mitochondrial genetic and enzymatic abnormalities in the Fischer 344 x Brown Norway F(1) hybrid rat heart. Journal of Molecular and Cellular Cardiology. 34: 17-28. PMID 11812161 DOI: 10.1006/Jmcc.2001.1483 |
0.725 |
|
2001 |
Cao Z, Wanagat J, McKiernan SH, Aiken JM. Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection. Nucleic Acids Research. 29: 4502-8. PMID 11691938 DOI: 10.1093/Nar/29.21.4502 |
0.795 |
|
2001 |
Wanagat J, Cao Z, Pathare P, Aiken JM. Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 322-32. PMID 11156948 DOI: 10.1096/Fj.00-0320Com |
0.81 |
|
2000 |
Lopez ME, Van Zeeland NL, Dahl DB, Weindruch R, Aiken JM. Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys. Mutation Research. 452: 123-38. PMID 10894897 DOI: 10.1016/S0027-5107(00)00059-2 |
0.766 |
|
1999 |
Van Zeeland NL, Wanagat J, Lopez ME, Aiken JM. Segmental nature of age-associated, skeletal muscle mitochondrial abnormalities necessitates three-dimensional analyses Journal of Anti-Aging Medicine. 2: 231-241. DOI: 10.1089/Rej.1.1999.2.231 |
0.84 |
|
1998 |
Lee CM, Aspnes LE, Chung SS, Weindruch R, Aiken JM. Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice. Annals of the New York Academy of Sciences. 854: 182-91. PMID 9928429 DOI: 10.1111/J.1749-6632.1998.Tb09901.X |
0.522 |
|
1998 |
Lee CM, Lopez ME, Weindruch R, Aiken JM. Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radical Biology & Medicine. 25: 964-72. PMID 9840742 DOI: 10.1016/S0891-5849(98)00185-3 |
0.773 |
|
1998 |
Schwarze SR, Weindruch R, Aiken JM. Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila. Free Radical Biology & Medicine. 25: 740-7. PMID 9801075 DOI: 10.1016/S0891-5849(98)00153-1 |
0.366 |
|
1998 |
Schwarze SR, Weindruch R, Aiken JM. Decreased mitochondrial RNA levels without accumulation of mitochondrial DNA deletions in aging Drosophila melanogaster. Mutation Research. 382: 99-107. PMID 9691990 DOI: 10.1016/S1383-5726(97)00013-7 |
0.46 |
|
1997 |
Aspnes LE, Lee CM, Weindruch R, Chung SS, Roecker EB, Aiken JM. Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 573-81. PMID 9212081 DOI: 10.1096/Fasebj.11.7.9212081 |
0.514 |
|
1997 |
Lee CM, Weindruch R, Aiken JM. Age-associated alterations of the mitochondrial genome. Free Radical Biology & Medicine. 22: 1259-69. PMID 9098100 DOI: 10.1016/S0891-5849(96)00546-1 |
0.464 |
|
1996 |
Eimon PM, Chung SS, Lee CM, Weindruch R, Aiken JM. Age-associated mitochondrial DNA deletions in mouse skeletal muscle: comparison of different regions of the mitochondrial genome. Developmental Genetics. 18: 107-13. PMID 8934872 DOI: 10.1002/(Sici)1520-6408(1996)18:2<107::Aid-Dvg3>3.0.Co;2-D |
0.503 |
|
1996 |
Chung SS, Eimon PM, Weindruch R, Aiken JM. Analysis of age-associated mitochondrial DNA deletion breakpoint regions from mice suggests a novel model of deletion formation Journal of the American Aging Association. 19: 117-128. DOI: 10.1007/Bf02434081 |
0.421 |
|
1995 |
Schwarze SR, Lee CM, Chung SS, Roecker EB, Weindruch R, Aiken JM. High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys. Mechanisms of Ageing and Development. 83: 91-101. PMID 8569289 DOI: 10.1016/0047-6374(95)01611-3 |
0.561 |
|
1994 |
Lee CM, Eimon P, Weindruch R, Aiken JM. Direct repeat sequences are not required at the breakpoints of age-associated mitochondrial DNA deletions in rhesus monkeys. Mechanisms of Ageing and Development. 75: 69-79. PMID 9128755 DOI: 10.1016/0047-6374(94)90029-9 |
0.494 |
|
1994 |
Chung SS, Weindruch R, Schwarze SR, McKenzie DI, Aiken JM. Multiple age-associated mitochondrial DNA deletions in skeletal muscle of mice. Aging (Milan, Italy). 6: 193-200. PMID 7993927 DOI: 10.1007/Bf03324239 |
0.516 |
|
1994 |
Bartz JC, McKenzie DI, Bessen RA, Marsh RF, Aiken JM. Transmissible mink encephalopathy species barrier effect between ferret and mink: PrP gene and protein analysis. The Journal of General Virology. 75: 2947-53. PMID 7964604 DOI: 10.1099/0022-1317-75-11-2947 |
0.305 |
|
1993 |
Lee CM, Chung SS, Kaczkowski JM, Weindruch R, Aiken JM. Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys Journals of Gerontology. 48. PMID 8227987 DOI: 10.1093/Geronj/48.6.B201 |
0.543 |
|
1991 |
Severson DW, Williamson JL, Aiken JM. Aging and transcriptional activity in worker honey bees Apidologie. 22: 105-108. DOI: 10.1051/Apido:19910202 |
0.302 |
|
1990 |
Aiken JM, Williamson JL, Borchardt LM, Marsh RF. Presence of mitochondrial D-loop DNA in scrapie-infected brain preparations enriched for the prion protein Journal of Virology. 64: 3265-3268. PMID 1972202 DOI: 10.1128/Jvi.64.7.3265-3268.1990 |
0.361 |
|
1989 |
Aiken JM, Williamson JL, Marsh RF. Evidence of mitochondrial involvement in scrapie infection Journal of Virology. 63: 1686-1694. PMID 2564438 DOI: 10.1128/Jvi.63.4.1686-1694.1989 |
0.338 |
|
Show low-probability matches. |