Photini Sinnis - Publications

Affiliations: 
New York University, New York, NY, United States 
Area:
Microbiology Biology, Molecular Biology, Cell Biology

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Hopp CS, Bennett BL, Mishra S, Lehmann C, Hanson KK, Lin JW, Rousseau K, Carvalho FA, van der Linden WA, Santos NC, Bogyo M, Khan SM, Heussler V, Sinnis P. Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites. Plos Pathogens. 13: e1006586. PMID 28922424 DOI: 10.1371/journal.ppat.1006586  0.72
2016 Voss C, Ehrenman K, Mlambo G, Mishra S, Kumar KA, Sacci JB, Sinnis P, Coppens I. Overexpression of Plasmodium berghei ATG8 by Liver Forms Leads to Cumulative Defects in Organelle Dynamics and to Generation of Noninfectious Merozoites. Mbio. 7. PMID 27353755 DOI: 10.1128/mBio.00682-16  1
2016 Swearingen KE, Lindner SE, Shi L, Shears MJ, Harupa A, Hopp CS, Vaughan AM, Springer TA, Moritz RL, Kappe SH, Sinnis P. Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics. Plos Pathogens. 12: e1005606. PMID 27128092 DOI: 10.1371/journal.ppat.1005606  1
2016 Hopp CS, Balaban AE, Bushell ES, Billker O, Rayner JC, Sinnis P. Palmitoyl transferases have critical roles in the development of mosquito and liver stages of Plasmodium. Cellular Microbiology. 18: 1625-1641. PMID 27084458 DOI: 10.1111/cmi.12601  1
2016 Moreira CK, Naissant B, Coppi A, Bennett BL, Aime E, Franke-Fayard B, Janse CJ, Coppens I, Sinnis P, Templeton TJ. The Plasmodium PHIST and RESA-Like Protein Families of Human and Rodent Malaria Parasites. Plos One. 11: e0152510. PMID 27022937 DOI: 10.1371/journal.pone.0152510  0.72
2015 Nemetski SM, Cardozo TJ, Bosch G, Weltzer R, O'Malley K, Ejigiri I, Kumar KA, Buscaglia CA, Nussenzweig V, Sinnis P, Levitskaya J, Bosch J. Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex. Malaria Journal. 14: 324. PMID 26289816 DOI: 10.1186/s12936-015-0834-9  1
2015 Hopp CS, Chiou K, Ragheb DR, Salman A, Khan SM, Liu AJ, Sinnis P. Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition. Elife. 4. PMID 26271010 DOI: 10.7554/eLife.07789  1
2015 Herrera R, Anderson C, Kumar K, Molina-Cruz A, Nguyen V, Burkhardt M, Reiter K, Shimp R, Howard RF, Srinivasan P, Nold MJ, Ragheb D, Shi L, DeCotiis M, Aebig J, ... ... Sinnis P, et al. Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains. Infection and Immunity. 83: 3771-80. PMID 26169272 DOI: 10.1128/IAI.02676-14  1
2015 Douglas RG, Amino R, Sinnis P, Frischknecht F. Active migration and passive transport of malaria parasites. Trends in Parasitology. 31: 357-62. PMID 26001482 DOI: 10.1016/j.pt.2015.04.010  1
2015 Espinosa DA, Gutierrez GM, Rojas-López M, Noe AR, Shi L, Tse SW, Sinnis P, Zavala F. Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies. The Journal of Infectious Diseases. PMID 25762791 DOI: 10.1093/infdis/jiv154  1
2015 Hopp CS, Sinnis P. The innate and adaptive response to mosquito saliva and Plasmodium sporozoites in the skin. Annals of the New York Academy of Sciences. 1342: 37-43. PMID 25694058 DOI: 10.1111/nyas.12661  1
2015 Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA. Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses. Plos Pathogens. 11: e1004637. PMID 25658939 DOI: 10.1371/journal.ppat.1004637  1
2015 Nemetski SM, Cardozo TJ, Bosch G, Weltzer R, O'Malley K, Ejigiri I, Kumar KA, Buscaglia CA, Nussenzweig V, Sinnis P, Levitskaya J, Bosch J. Inhibition by stabilization: Targeting the Plasmodium falciparum aldolase-TRAP complex Malaria Journal. 14. DOI: 10.1186/s12936-015-0834-9  1
2014 Ferguson DJ, Balaban AE, Patzewitz EM, Wall RJ, Hopp CS, Poulin B, Mohmmed A, Malhotra P, Coppi A, Sinnis P, Tewari R. The repeat region of the circumsporozoite protein is critical for sporozoite formation and maturation in Plasmodium. Plos One. 9: e113923. PMID 25438048 DOI: 10.1371/journal.pone.0113923  1
2014 Lehmann C, Heitmann A, Mishra S, Burda PC, Singer M, Prado M, Niklaus L, Lacroix C, Ménard R, Frischknecht F, Stanway R, Sinnis P, Heussler V. A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development. Plos Pathogens. 10: e1004336. PMID 25166051 DOI: 10.1371/journal.ppat.1004336  1
2014 Sack BK, Miller JL, Vaughan AM, Douglass A, Kaushansky A, Mikolajczak S, Coppi A, Gonzalez-Aseguinolaza G, Tsuji M, Zavala F, Sinnis P, Kappe SH. Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum. Infection and Immunity. 82: 808-17. PMID 24478094 DOI: 10.1128/IAI.01249-13  1
2013 Hobbs CV, De La Vega P, Penzak SR, Van Vliet J, Krzych U, Sinnis P, Borkowsky W, Duffy PE. The effect of antiretrovirals on Plasmodium falciparum liver stages. Aids (London, England). 27: 1674-7. PMID 23907270 DOI: 10.1097/QAD.0b013e3283621dd4  1
2013 Falkard B, Kumar TR, Hecht LS, Matthews KA, Henrich PP, Gulati S, Lewis RE, Manary MJ, Winzeler EA, Sinnis P, Prigge ST, Heussler V, Deschermeier C, Fidock D. A key role for lipoic acid synthesis during Plasmodium liver stage development. Cellular Microbiology. 15: 1585-604. PMID 23490300 DOI: 10.1111/cmi.12137  1
2013 Millholland MG, Mishra S, Dupont CD, Love MS, Patel B, Shilling D, Kazanietz MG, Foskett JK, Hunter CA, Sinnis P, Greenbaum DC. A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites. Cell Host & Microbe. 13: 15-28. PMID 23332153 DOI: 10.1016/j.chom.2012.12.001  1
2013 Lindner SE, Swearingen KE, Harupa A, Vaughan AM, Sinnis P, Moritz RL, Kappe SH. Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Molecular & Cellular Proteomics : McP. 12: 1127-43. PMID 23325771 DOI: 10.1074/mcp.M112.024505  1
2013 Sinnis P, De La Vega P, Coppi A, Krzych U, Mota MM. Quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 923: 385-400. PMID 22990793 DOI: 10.1007/978-1-62703-026-7_27  1
2012 Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W, Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW, Poncz M, DeGrado WF, ... Sinnis P, et al. Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host & Microbe. 12: 815-23. PMID 23245326 DOI: 10.1016/j.chom.2012.10.017  1
2012 Hobbs CV, Voza T, De La Vega P, Vanvliet J, Conteh S, Penzak SR, Fay MP, Anders N, Ilmet T, Li Y, Borkowsky W, Krzych U, Duffy PE, Sinnis P. HIV nonnucleoside reverse transcriptase inhibitors and trimethoprim-sulfamethoxazole inhibit plasmodium liver stages. The Journal of Infectious Diseases. 206: 1706-14. PMID 23125449 DOI: 10.1093/infdis/jis602  1
2012 Sinnis P, Zavala F. The skin: where malaria infection and the host immune response begin. Seminars in Immunopathology. 34: 787-92. PMID 23053392 DOI: 10.1007/s00281-012-0345-5  1
2012 Ejigiri I, Ragheb DR, Pino P, Coppi A, Bennett BL, Soldati-Favre D, Sinnis P. Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity. Plos Pathogens. 8: e1002725. PMID 22911675 DOI: 10.1371/journal.ppat.1002725  1
2012 Das A, Anvikar AR, Cator LJ, Dhiman RC, Eapen A, Mishra N, Nagpal BN, Nanda N, Raghavendra K, Read AF, Sharma SK, Singh OP, Singh V, Sinnis P, Srivastava HC, et al. Malaria in India: the center for the study of complex malaria in India. Acta Tropica. 121: 267-73. PMID 22142788 DOI: 10.1016/j.actatropica.2011.11.008  1
2011 Vera IM, Beatty WL, Sinnis P, Kim K. Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole. Plos Pathogens. 7: e1002197. PMID 21909259 DOI: 10.1371/journal.ppat.1002197  1
2011 Cockburn IA, Tse SW, Radtke AJ, Srinivasan P, Chen YC, Sinnis P, Zavala F. Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. Plos Pathogens. 7: e1001318. PMID 21445239 DOI: 10.1371/journal.ppat.1001318  1
2011 Ecker A, Lakshmanan V, Sinnis P, Coppens I, Fidock DA. Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes. The Journal of Infectious Diseases. 203: 228-36. PMID 21288823 DOI: 10.1093/infdis/jiq036  1
2011 Coppi A, Natarajan R, Pradel G, Bennett BL, James ER, Roggero MA, Corradin G, Persson C, Tewari R, Sinnis P. The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host. The Journal of Experimental Medicine. 208: 341-56. PMID 21262960 DOI: 10.1084/jem.20101488  1
2010 Bennett BL, Sinnis P. What can we learn from an unnatural immune response? Trends in Parasitology. 26: 319-21. PMID 20430697 DOI: 10.1016/j.pt.2010.02.011  1
2010 Kortagere S, Welsh WJ, Morrisey JM, Daly T, Ejigiri I, Sinnis P, Vaidya AB, Bergman LW. Structure-based design of novel small-molecule inhibitors of Plasmodium falciparum. Journal of Chemical Information and Modeling. 50: 840-9. PMID 20426475 DOI: 10.1021/ci100039k  1
2009 Mwakingwe A, Ting LM, Hochman S, Chen J, Sinnis P, Kim K. Noninvasive real-time monitoring of liver-stage development of bioluminescent Plasmodium parasites. The Journal of Infectious Diseases. 200: 1470-8. PMID 19811100 DOI: 10.1086/606115  1
2009 Ejigiri I, Sinnis P. Plasmodium sporozoite-host interactions from the dermis to the hepatocyte. Current Opinion in Microbiology. 12: 401-7. PMID 19608456 DOI: 10.1016/j.mib.2009.06.006  1
2009 Hobbs CV, Voza T, Coppi A, Kirmse B, Marsh K, Borkowsky W, Sinnis P. HIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites. The Journal of Infectious Diseases. 199: 134-41. PMID 19032102 DOI: 10.1086/594369  1
2008 Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, ... ... Sinnis P, et al. The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host & Microbe. 4: 567-78. PMID 19064257 DOI: 10.1016/j.chom.2008.11.001  1
2008 Belnoue E, Voza T, Costa FT, Grüner AC, Mauduit M, Rosa DS, Depinay N, Kayibanda M, Vigário AM, Mazier D, Snounou G, Sinnis P, Rénia L. Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage. Journal of Immunology (Baltimore, Md. : 1950). 181: 8552-8. PMID 19050274  1
2008 Ting LM, Gissot M, Coppi A, Sinnis P, Kim K. Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nature Medicine. 14: 954-8. PMID 18758447 DOI: 10.1038/nm.1867  1
2008 Sinnis P, Zavala F. The skin stage of malaria infection: biology and relevance to the malaria vaccine effort. Future Microbiology. 3: 275-8. PMID 18505393 DOI: 10.2217/17460913.3.3.275  1
2008 Sinnis P, Ernst JD. CO-opting the host HO-1 pathway in tuberculosis and malaria. Cell Host & Microbe. 3: 277-9. PMID 18474353 DOI: 10.1016/j.chom.2008.04.009  1
2008 Gissot M, Ting LM, Daly TM, Bergman LW, Sinnis P, Kim K. High mobility group protein HMGB2 is a critical regulator of plasmodium oocyst development. The Journal of Biological Chemistry. 283: 17030-8. PMID 18400754 DOI: 10.1074/jbc.M801637200  1
2008 Moreira CK, Templeton TJ, Lavazec C, Hayward RE, Hobbs CV, Kroeze H, Janse CJ, Waters AP, Sinnis P, Coppi A. The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cellular Microbiology. 10: 1505-16. PMID 18346224 DOI: 10.1111/j.1462-5822.2008.01143.x  1
2007 Grüner AC, Mauduit M, Tewari R, Romero JF, Depinay N, Kayibanda M, Lallemand E, Chavatte JM, Crisanti A, Sinnis P, Mazier D, Corradin G, Snounou G, Rénia L. Sterile protection against malaria is independent of immune responses to the circumsporozoite protein. Plos One. 2: e1371. PMID 18159254 DOI: 10.1371/journal.pone.0001371  1
2007 Coppi A, Tewari R, Bishop JR, Bennett BL, Lawrence R, Esko JD, Billker O, Sinnis P. Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells. Cell Host & Microbe. 2: 316-27. PMID 18005753 DOI: 10.1016/j.chom.2007.10.002  1
2007 Kelly BA, Neil SJ, McKnight A, Santos JM, Sinnis P, Jack ER, Middleton DA, Dobson CB. Apolipoprotein E-derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity. The Febs Journal. 274: 4511-25. PMID 17681018 DOI: 10.1111/j.1742-4658.2007.05981.x  1
2007 Sinnis P, Coppi A, Toida T, Toyoda H, Kinoshita-Toyoda A, Xie J, Kemp MM, Linhardt RJ. Mosquito heparan sulfate and its potential role in malaria infection and transmission. The Journal of Biological Chemistry. 282: 25376-84. PMID 17597060 DOI: 10.1074/jbc.M704698200  1
2007 Sinnis P, Coppi A. A long and winding road: the Plasmodium sporozoite's journey in the mammalian host. Parasitology International. 56: 171-8. PMID 17513164 DOI: 10.1016/j.parint.2007.04.002  1
2007 Bhandari R, Janos DP, Sinnis P. Furuncular myiasis caused by Dermatobia hominis in a returning traveler. The American Journal of Tropical Medicine and Hygiene. 76: 598-9. PMID 17360891  1
2007 Yamauchi LM, Coppi A, Snounou G, Sinnis P. Plasmodium sporozoites trickle out of the injection site. Cellular Microbiology. 9: 1215-22. PMID 17223931 DOI: 10.1111/j.1462-5822.2006.00861.x  1
2006 Coppi A, Cabinian M, Mirelman D, Sinnis P. Antimalarial activity of allicin, a biologically active compound from garlic cloves. Antimicrobial Agents and Chemotherapy. 50: 1731-7. PMID 16641443 DOI: 10.1128/AAC.50.5.1731-1737.2006  1
2006 Engelmann S, Sinnis P, Matuschewski K. Transgenic Plasmodium berghei sporozoites expressing beta-galactosidase for quantification of sporozoite transmission. Molecular and Biochemical Parasitology. 146: 30-7. PMID 16316690 DOI: 10.1016/j.molbiopara.2005.10.015  1
2005 Medica DL, Sinnis P. Quantitative dynamics of Plasmodium yoelii sporozoite transmission by infected anopheline mosquitoes. Infection and Immunity. 73: 4363-9. PMID 15972531 DOI: 10.1128/IAI.73.7.4363-4369.2005  1
2005 Coppi A, Pinzon-Ortiz C, Hutter C, Sinnis P. The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion. The Journal of Experimental Medicine. 201: 27-33. PMID 15630135 DOI: 10.1084/jem.20040989  1
2004 Myung JM, Marshall P, Sinnis P. The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites. Molecular and Biochemical Parasitology. 133: 53-9. PMID 14668012 DOI: 10.1016/j.molbiopara.2003.09.002  1
2002 Sinnis P, Nardin E. Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein. Chemical Immunology. 80: 70-96. PMID 12058652  1
2002 Sinnis P, Febbraio M. Plasmodium yoelii sporozoites infect CD36-deficient mice. Experimental Parasitology. 100: 12-6. PMID 11971649 DOI: 10.1006/expr.2001.4676  1
2001 Pinzon-Ortiz C, Friedman J, Esko J, Sinnis P. The Binding of the Circumsporozoite Protein to Cell Surface Heparan Sulfate Proteoglycans is Required for Plasmodium Sporozoite Attachment to Target Cells Journal of Biological Chemistry. 276: 26784-26791. PMID 11352923 DOI: 10.1074/jbc.M104038200  1
2000 Marshall P, Rohlmann A, Nussenzweig V, Herz J, Sinnis P. Plasmodium sporozoites invade cells with targeted deletions in the LDL receptor related protein Molecular and Biochemical Parasitology. 106: 293-298. PMID 10699258 DOI: 10.1016/S0166-6851(99)00210-8  1
1998 Sinnis P. An immunoradiometric assay for the quantification of Plasmodium sporozoite invasion of HepG2 cells Journal of Immunological Methods. 221: 17-23. PMID 9894894 DOI: 10.1016/S0022-1759(98)00151-3  1
1998 Gantt SM, Myung JM, Briones MR, Li WD, Corey EJ, Omura S, Nussenzweig V, Sinnis P. Proteasome inhibitors block development of Plasmodium spp. Antimicrobial Agents and Chemotherapy. 42: 2731-8. PMID 9756786  1
1997 Sidjanski SP, Vanderberg JP, Sinnis P. Anopheles stephensi salivary glands bear receptors for region I of the circumsporozoite protein of Plasmodium falciparum Molecular and Biochemical Parasitology. 90: 33-41. PMID 9497030 DOI: 10.1016/S0166-6851(97)00124-2  1
1997 Gantt SM, Clavijo P, Bai X, Esko JD, Sinnis P. Cell adhesion to a motif shared by the malaria circumsporozoite protein and thrombospondin is mediated by its glycosaminoglycan-binding region and not by CSVTCG. The Journal of Biological Chemistry. 272: 19205-13. PMID 9235912 DOI: 10.1074/jbc.272.31.19205  1
1997 Sinnis P, Sim BKL. Cell invasion by the vertebrate stages of Plasmodium Trends in Microbiology. 5: 52-58. PMID 9108930 DOI: 10.1016/S0966-842X(97)84657-4  1
1996 Sinnis P, Willnow TT, Briones MRS, Herz J, Nussenzweig V. Remnant lipoproteins inhibits malaria sporozoite invasion of hepatocytes Journal of Experimental Medicine. 184: 945-954. PMID 9064354  1
1996 Frevert U, Sinnis P, Esko JD, Nussenzweig V. Cell surface glycosaminoglycans are not obligatory for Plasmodium berghei sporozoite invasion in vitro Molecular and Biochemical Parasitology. 76: 257-266. PMID 8920011 DOI: 10.1016/0166-6851(95)02563-4  1
1996 Sinnis P. The malaria sporozoite's journey into the liver Infectious Agents and Disease. 5: 182-189. PMID 8805080  1
1996 Sinnis P. Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes Journal of Investigative Medicine. 44.  1
1994 Cerami C, Frevert U, Sinnis P, Takacs B, Nussenzweig V. Rapid clearance of malaria circumsporozoite protein (CS) by hepatocytes Journal of Experimental Medicine. 179: 695-701. PMID 8294876  1
1994 Sinnis P, Clavijo P, Fenyö D, Chait BT, Cerami C, Nussenzweig V. Structural and functional properties of region II-plus of the malaria circumsporozoite protein Journal of Experimental Medicine. 180: 297-306. PMID 8006589 DOI: 10.1084/jem.180.1.297  1
1993 Frevert U, Sinnis P, Cerami C, Shreffler W, Takacs B, Nussenzweig V. Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. The Journal of Experimental Medicine. 177: 1287-98. PMID 8478608  1
1992 Cerami C, Frevert U, Sinnis P, Takacs B, Clavijo P, Santos MJ, Nussenzweig V. The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of plasmodium falciparum sporozoites Cell. 70: 1021-1033. PMID 1326407 DOI: 10.1016/0092-8674(92)90251-7  1
1988 Sinnis P, Wellems TE. Long-range restriction maps of Plasmodium falciparum chromosomes: Crossingover and size variation among geographically distant isolates Genomics. 3: 287-295. PMID 3072285 DOI: 10.1016/0888-7543(88)90117-6  1
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