| Year |
Citation |
Score |
| 2024 |
Kanatani S, Stiffler D, Bousema T, Yenokyan G, Sinnis P. Revisiting the Plasmodium sporozoite inoculum and elucidating the efficiency with which malaria parasites progress through the mosquito. Nature Communications. 15: 748. PMID 38272943 DOI: 10.1038/s41467-024-44962-4 |
0.425 |
|
| 2023 |
Balta VA, Stiffler D, Sayeed A, Tripathi AK, Elahi R, Mlambo G, Bakshi RP, Dziedzic AG, Jedlicka AE, Nenortas E, Romero-Rodriguez K, Canonizado MA, Mann A, Owen A, Sullivan DJ, ... ... Sinnis P, et al. Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito. Nature Communications. 14: 6415. PMID 37828012 DOI: 10.1038/s41467-023-42030-x |
0.35 |
|
| 2023 |
Arora G, Chuang YM, Sinnis P, Dimopoulos G, Fikrig E. Malaria: influence of Anopheles mosquito saliva on Plasmodium infection. Trends in Immunology. 44: 256-265. PMID 36964020 DOI: 10.1016/j.it.2023.02.005 |
0.479 |
|
| 2023 |
Balta VA, Stiffler D, Sayeed A, Tripathi AK, Elahi R, Mlambo G, Bakshi RP, Dziedzic AG, Jedlicka AE, Nenortas E, Romero-Rodriguez K, Canonizado MA, Mann A, Owen A, Sullivan DJ, ... ... Sinnis P, et al. Transmissibility of clinically relevant atovaquone-resistant by anopheline mosquitoes. Biorxiv : the Preprint Server For Biology. PMID 36798298 DOI: 10.1101/2023.02.07.527535 |
0.339 |
|
| 2023 |
Marques-da-Silva C, Poudel B, Baptista RP, Peissig K, Hancox LS, Shiau JC, Pewe LL, Shears MJ, Kanneganti TD, Sinnis P, Kyle DE, Gurung P, Harty JT, Kurup SP. AIM2 sensors mediate immunity to infection in hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2210181120. PMID 36595704 DOI: 10.1073/pnas.2210181120 |
0.432 |
|
| 2022 |
Kanatani S, Elahi R, Kanchanabhogin S, Vartak N, Tripathi AK, Prigge ST, Sinnis P. Screening the Pathogen Box for Inhibition of Plasmodium falciparum Sporozoite Motility Reveals a Critical Role for Kinases in Transmission Stages. Antimicrobial Agents and Chemotherapy. e0041822. PMID 35943271 DOI: 10.1128/aac.00418-22 |
0.42 |
|
| 2022 |
Lindner SE, Swearingen KE, Shears MJ, Sebastian A, Walker MP, Vrana EN, Hart KJ, Minns AM, Albert I, Sinnis P, Moritz RL, Kappe SHI. Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites. Nature Communications. 13: 283. PMID 34992211 DOI: 10.1038/s41467-021-27767-7 |
0.314 |
|
| 2021 |
Tan J, Cho H, Pholcharee T, Pereira LS, Doumbo S, Doumtabe D, Flynn BJ, Schön A, Kanatani S, Aylor SO, Oyen D, Vistein R, Wang L, Dillon M, Skinner J, ... ... Sinnis P, et al. Functional human IgA targets a conserved site on malaria sporozoites. Science Translational Medicine. 13. PMID 34162751 DOI: 10.1126/scitranslmed.abg2344 |
0.379 |
|
| 2021 |
Hopp CS, Kanatani S, Archer NK, Miller RJ, Liu H, Chiou KK, Miller LS, Sinnis P. Comparative intravital imaging of human and rodent malaria sporozoites reveals the skin is not a species-specific barrier. Embo Molecular Medicine. e11796. PMID 33750026 DOI: 10.15252/emmm.201911796 |
0.329 |
|
| 2021 |
Alves E Silva TL, Radtke A, Balaban A, Pascini TV, Pala ZR, Roth A, Alvarenga PH, Jeong YJ, Olivas J, Ghosh AK, Bui H, Pybus BS, Sinnis P, Jacobs-Lorena M, Vega-Rodríguez J. The fibrinolytic system enables the onset of infection in the mosquito vector and the mammalian host. Science Advances. 7. PMID 33547079 DOI: 10.1126/sciadv.abe3362 |
0.473 |
|
| 2020 |
Tripathi AK, Mlambo G, Kanatani S, Sinnis P, Dimopoulos G. Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding. Journal of Visualized Experiments : Jove. PMID 32716382 DOI: 10.3791/61426 |
0.521 |
|
| 2020 |
Graumans W, Jacobs E, Bousema T, Sinnis P. When Is a Plasmodium-Infected Mosquito an Infectious Mosquito? Trends in Parasitology. 36: 705-716. PMID 32620501 DOI: 10.1016/J.Pt.2020.05.011 |
0.524 |
|
| 2020 |
Aleshnick M, Ganusov VV, Nasir G, Yenokyan G, Sinnis P. Experimental determination of the force of malaria infection reveals a non-linear relationship to mosquito sporozoite loads. Plos Pathogens. 16: e1008181. PMID 32453765 DOI: 10.1371/Journal.Ppat.1008181 |
0.504 |
|
| 2019 |
Lindner SE, Swearingen KE, Shears MJ, Walker MP, Vrana EN, Hart KJ, Minns AM, Sinnis P, Moritz RL, Kappe SHI. Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites. Nature Communications. 10: 4964. PMID 31673027 DOI: 10.1038/S41467-019-12936-6 |
0.556 |
|
| 2019 |
McLean KJ, Straimer J, Hopp CS, Vega-Rodriguez J, Small-Saunders JL, Kanatani S, Tripathi A, Mlambo G, Dumoulin PC, Harris CT, Tong X, Shears MJ, Ankarklev J, Kafsack BFC, Fidock DA, ... Sinnis P, et al. Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters. Scientific Reports. 9: 13131. PMID 31511546 DOI: 10.1038/S41598-019-49348-X |
0.484 |
|
| 2019 |
Sinnis P, Zavala F. Reply to Vanderberg, "Further Mechanisms and Locations in Which Antisporozoite Antibodies Neutralize Malaria Sporozoites". Mbio. 10. PMID 31506316 DOI: 10.1128/Mbio.02108-19 |
0.323 |
|
| 2019 |
Shears MJ, Sekhar Nirujogi R, Swearingen KE, Renuse S, Mishra S, Jaipal Reddy P, Moritz RL, Pandey A, Sinnis P. Proteomic Analysis of Merosomes: The Link between Liver and Blood Stages in Malaria. Journal of Proteome Research. PMID 31335145 DOI: 10.1021/Acs.Jproteome.9B00324 |
0.489 |
|
| 2019 |
Poti KE, Balaban AE, Pal P, Kobayashi T, Goldberg DE, Sinnis P, Sullivan DJ. In vivo compartmental kinetics of Plasmodium falciparum histidine-rich protein II in the blood of humans and in BALB/c mice infected with a transgenic Plasmodium berghei parasite expressing histidine-rich protein II. Malaria Journal. 18: 78. PMID 30866956 DOI: 10.1186/S12936-019-2712-3 |
0.425 |
|
| 2018 |
Dundas K, Shears MJ, Sinnis P, Wright GJ. Important Extracellular Interactions between Plasmodium Sporozoites and Host Cells Required for Infection. Trends in Parasitology. PMID 30583849 DOI: 10.1016/J.Pt.2018.11.008 |
0.543 |
|
| 2018 |
Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, ... ... Sinnis P, et al. Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine. PMID 30552419 DOI: 10.1038/S41591-018-0315-0 |
0.311 |
|
| 2018 |
Flores-Garcia Y, Nasir G, Hopp CS, Munoz C, Balaban AE, Zavala F, Sinnis P. Antibody-Mediated Protection against Sporozoites Begins at the Dermal Inoculation Site. Mbio. 9. PMID 30459199 DOI: 10.1128/Mbio.02194-18 |
0.452 |
|
| 2018 |
Schleicher TR, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, Graham M, Mlambo G, Tripathi AK, Li Y, Cresswell P, Sinnis P, Dimopoulos G, Fikrig E. A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission. Nature Communications. 9: 2908. PMID 30046053 DOI: 10.1038/S41467-018-05374-3 |
0.57 |
|
| 2018 |
Bunnik EM, Cook KB, Varoquaux N, Batugedara G, Prudhomme J, Cort A, Shi L, Andolina C, Ross LS, Brady D, Fidock DA, Nosten F, Tewari R, Sinnis P, Ay F, et al. Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages. Nature Communications. 9: 1910. PMID 29765020 DOI: 10.1038/S41467-018-04295-5 |
0.442 |
|
| 2018 |
Dundas K, Shears MJ, Sun Y, Hopp CS, Crosnier C, Metcalf T, Girling G, Sinnis P, Billker O, Wright GJ. Alpha-v-containing integrins are host receptors for the sporozoite surface protein, TRAP. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632205 DOI: 10.1073/Pnas.1719660115 |
0.486 |
|
| 2018 |
Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Scho N A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, ... ... Sinnis P, et al. A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine. PMID 29554083 DOI: 10.1038/Nm.4512 |
0.388 |
|
| 2018 |
Dellibovi-Ragheb TA, Jhun H, Goodman CD, Walters MS, Ragheb DRT, Matthews KA, Rajaram K, Mishra S, McFadden GI, Sinnis P, Prigge ST. Host biotin is required for liver stage development in malaria parasites. Proceedings of the National Academy of Sciences of the United States of America. PMID 29483266 DOI: 10.1073/Pnas.1800717115 |
0.526 |
|
| 2017 |
Wirth DF, Winzeler EA, Fenton B, Adams JH, Ariey F, Barillas-Mury CV, Baum J, Bhatia SN, Billker O, Bopp SE, Catteruccia F, Cowman AF, Chitnis CE, Crabb BS, Deitsch KW, ... ... Sinnis P, et al. malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication Plos Medicine. 14. PMID 29190277 DOI: 10.1371/Journal.Pmed.1002451 |
0.304 |
|
| 2017 |
Hopp CS, Bennett BL, Mishra S, Lehmann C, Hanson KK, Lin JW, Rousseau K, Carvalho FA, van der Linden WA, Santos NC, Bogyo M, Khan SM, Heussler V, Sinnis P. Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites. Plos Pathogens. 13: e1006586. PMID 28922424 DOI: 10.1371/Journal.Ppat.1006586 |
0.82 |
|
| 2017 |
Pal P, Balaban AE, Diamond MS, Sinnis P, Klein RS, Goldberg DE. Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice. Plos One. 12: e0177142. PMID 28475625 DOI: 10.1371/Journal.Pone.0177142 |
0.414 |
|
| 2017 |
Aguiar AC, Figueiredo FJ, Neuenfeldt PD, Katsuragawa TH, Drawanz BB, Cunico W, Sinnis P, Zavala F, Krettli AU. Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms. Malaria Journal. 16: 110. PMID 28279180 DOI: 10.1186/S12936-017-1755-6 |
0.421 |
|
| 2016 |
Voss C, Ehrenman K, Mlambo G, Mishra S, Kumar KA, Sacci JB, Sinnis P, Coppens I. Overexpression of Plasmodium berghei ATG8 by Liver Forms Leads to Cumulative Defects in Organelle Dynamics and to Generation of Noninfectious Merozoites. Mbio. 7. PMID 27353755 DOI: 10.1128/Mbio.00682-16 |
0.572 |
|
| 2016 |
Swearingen KE, Lindner SE, Shi L, Shears MJ, Harupa A, Hopp CS, Vaughan AM, Springer TA, Moritz RL, Kappe SH, Sinnis P. Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics. Plos Pathogens. 12: e1005606. PMID 27128092 DOI: 10.1371/Journal.Ppat.1005606 |
0.395 |
|
| 2016 |
Hopp CS, Balaban AE, Bushell ES, Billker O, Rayner JC, Sinnis P. Palmitoyl transferases have critical roles in the development of mosquito and liver stages of Plasmodium. Cellular Microbiology. 18: 1625-1641. PMID 27084458 DOI: 10.1111/Cmi.12601 |
0.561 |
|
| 2016 |
Moreira CK, Naissant B, Coppi A, Bennett BL, Aime E, Franke-Fayard B, Janse CJ, Coppens I, Sinnis P, Templeton TJ. The Plasmodium PHIST and RESA-Like Protein Families of Human and Rodent Malaria Parasites. Plos One. 11: e0152510. PMID 27022937 DOI: 10.1371/Journal.Pone.0152510 |
0.774 |
|
| 2015 |
Nemetski SM, Cardozo TJ, Bosch G, Weltzer R, O'Malley K, Ejigiri I, Kumar KA, Buscaglia CA, Nussenzweig V, Sinnis P, Levitskaya J, Bosch J. Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex. Malaria Journal. 14: 324. PMID 26289816 DOI: 10.1186/S12936-015-0834-9 |
0.8 |
|
| 2015 |
Hopp CS, Chiou K, Ragheb DR, Salman A, Khan SM, Liu AJ, Sinnis P. Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition. Elife. 4. PMID 26271010 DOI: 10.7554/Elife.07789 |
0.424 |
|
| 2015 |
Herrera R, Anderson C, Kumar K, Molina-Cruz A, Nguyen V, Burkhardt M, Reiter K, Shimp R, Howard RF, Srinivasan P, Nold MJ, Ragheb D, Shi L, DeCotiis M, Aebig J, ... ... Sinnis P, et al. Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains. Infection and Immunity. 83: 3771-80. PMID 26169272 DOI: 10.1128/Iai.02676-14 |
0.36 |
|
| 2015 |
Douglas RG, Amino R, Sinnis P, Frischknecht F. Active migration and passive transport of malaria parasites. Trends in Parasitology. 31: 357-62. PMID 26001482 DOI: 10.1016/J.Pt.2015.04.010 |
0.552 |
|
| 2015 |
Espinosa DA, Gutierrez GM, Rojas-López M, Noe AR, Shi L, Tse SW, Sinnis P, Zavala F. Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies. The Journal of Infectious Diseases. PMID 25762791 DOI: 10.1093/Infdis/Jiv154 |
0.456 |
|
| 2015 |
Hopp CS, Sinnis P. The innate and adaptive response to mosquito saliva and Plasmodium sporozoites in the skin. Annals of the New York Academy of Sciences. 1342: 37-43. PMID 25694058 DOI: 10.1111/Nyas.12661 |
0.535 |
|
| 2015 |
Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA. Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses. Plos Pathogens. 11: e1004637. PMID 25658939 DOI: 10.1371/Journal.Ppat.1004637 |
0.384 |
|
| 2015 |
Nemetski SM, Cardozo TJ, Bosch G, Weltzer R, O'Malley K, Ejigiri I, Kumar KA, Buscaglia CA, Nussenzweig V, Sinnis P, Levitskaya J, Bosch J. Inhibition by stabilization: Targeting the Plasmodium falciparum aldolase-TRAP complex Malaria Journal. 14. DOI: 10.1186/s12936-015-0834-9 |
0.745 |
|
| 2015 |
Boucher LE, Hopp CS, Sinnis P, Bosch J. Identification and Characterization of Protein-Protein Interaction Effectors Targeting the Invasion Machinery of the Malaria Parasite Biophysical Journal. 108: 356a-357a. DOI: 10.1016/J.Bpj.2014.11.1953 |
0.5 |
|
| 2014 |
Ferguson DJ, Balaban AE, Patzewitz EM, Wall RJ, Hopp CS, Poulin B, Mohmmed A, Malhotra P, Coppi A, Sinnis P, Tewari R. The repeat region of the circumsporozoite protein is critical for sporozoite formation and maturation in Plasmodium. Plos One. 9: e113923. PMID 25438048 DOI: 10.1371/Journal.Pone.0113923 |
0.488 |
|
| 2014 |
Lehmann C, Heitmann A, Mishra S, Burda PC, Singer M, Prado M, Niklaus L, Lacroix C, Ménard R, Frischknecht F, Stanway R, Sinnis P, Heussler V. A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development. Plos Pathogens. 10: e1004336. PMID 25166051 DOI: 10.1371/Journal.Ppat.1004336 |
0.565 |
|
| 2014 |
Sack BK, Miller JL, Vaughan AM, Douglass A, Kaushansky A, Mikolajczak S, Coppi A, Gonzalez-Aseguinolaza G, Tsuji M, Zavala F, Sinnis P, Kappe SH. Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum. Infection and Immunity. 82: 808-17. PMID 24478094 DOI: 10.1128/Iai.01249-13 |
0.483 |
|
| 2014 |
Hopp C, Sinnis P. The ins and outs of sporozoite biology in the dermis Malaria Journal. 13. DOI: 10.1186/1475-2875-13-S1-O6 |
0.492 |
|
| 2013 |
Hobbs CV, De La Vega P, Penzak SR, Van Vliet J, Krzych U, Sinnis P, Borkowsky W, Duffy PE. The effect of antiretrovirals on Plasmodium falciparum liver stages. Aids (London, England). 27: 1674-7. PMID 23907270 DOI: 10.1097/Qad.0B013E3283621Dd4 |
0.404 |
|
| 2013 |
Falkard B, Kumar TR, Hecht LS, Matthews KA, Henrich PP, Gulati S, Lewis RE, Manary MJ, Winzeler EA, Sinnis P, Prigge ST, Heussler V, Deschermeier C, Fidock D. A key role for lipoic acid synthesis during Plasmodium liver stage development. Cellular Microbiology. 15: 1585-604. PMID 23490300 DOI: 10.1111/Cmi.12137 |
0.467 |
|
| 2013 |
Millholland MG, Mishra S, Dupont CD, Love MS, Patel B, Shilling D, Kazanietz MG, Foskett JK, Hunter CA, Sinnis P, Greenbaum DC. A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites. Cell Host & Microbe. 13: 15-28. PMID 23332153 DOI: 10.1016/J.Chom.2012.12.001 |
0.536 |
|
| 2013 |
Lindner SE, Swearingen KE, Harupa A, Vaughan AM, Sinnis P, Moritz RL, Kappe SH. Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Molecular & Cellular Proteomics : McP. 12: 1127-43. PMID 23325771 DOI: 10.1074/Mcp.M112.024505 |
0.55 |
|
| 2013 |
Sinnis P, De La Vega P, Coppi A, Krzych U, Mota MM. Quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 923: 385-400. PMID 22990793 DOI: 10.1007/978-1-62703-026-7_27 |
0.52 |
|
| 2012 |
Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W, Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW, Poncz M, DeGrado WF, ... Sinnis P, et al. Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host & Microbe. 12: 815-23. PMID 23245326 DOI: 10.1016/J.Chom.2012.10.017 |
0.516 |
|
| 2012 |
Hobbs CV, Voza T, De La Vega P, Vanvliet J, Conteh S, Penzak SR, Fay MP, Anders N, Ilmet T, Li Y, Borkowsky W, Krzych U, Duffy PE, Sinnis P. HIV nonnucleoside reverse transcriptase inhibitors and trimethoprim-sulfamethoxazole inhibit plasmodium liver stages. The Journal of Infectious Diseases. 206: 1706-14. PMID 23125449 DOI: 10.1093/Infdis/Jis602 |
0.459 |
|
| 2012 |
Sinnis P, Zavala F. The skin: where malaria infection and the host immune response begin. Seminars in Immunopathology. 34: 787-92. PMID 23053392 DOI: 10.1007/S00281-012-0345-5 |
0.504 |
|
| 2012 |
Ejigiri I, Ragheb DR, Pino P, Coppi A, Bennett BL, Soldati-Favre D, Sinnis P. Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity. Plos Pathogens. 8: e1002725. PMID 22911675 DOI: 10.1371/Journal.Ppat.1002725 |
0.744 |
|
| 2012 |
Voza T, Miller JL, Kappe SH, Sinnis P. Extrahepatic exoerythrocytic forms of rodent malaria parasites at the site of inoculation: clearance after immunization, susceptibility to primaquine, and contribution to blood-stage infection. Infection and Immunity. 80: 2158-64. PMID 22431651 DOI: 10.1128/Iai.00246-12 |
0.537 |
|
| 2012 |
Das A, Anvikar AR, Cator LJ, Dhiman RC, Eapen A, Mishra N, Nagpal BN, Nanda N, Raghavendra K, Read AF, Sharma SK, Singh OP, Singh V, Sinnis P, Srivastava HC, et al. Malaria in India: the center for the study of complex malaria in India. Acta Tropica. 121: 267-73. PMID 22142788 DOI: 10.1016/J.Actatropica.2011.11.008 |
0.427 |
|
| 2011 |
Vera IM, Beatty WL, Sinnis P, Kim K. Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole. Plos Pathogens. 7: e1002197. PMID 21909259 DOI: 10.1371/Journal.Ppat.1002197 |
0.579 |
|
| 2011 |
Cockburn IA, Tse SW, Radtke AJ, Srinivasan P, Chen YC, Sinnis P, Zavala F. Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. Plos Pathogens. 7: e1001318. PMID 21445239 DOI: 10.1371/Journal.Ppat.1001318 |
0.43 |
|
| 2011 |
Ecker A, Lakshmanan V, Sinnis P, Coppens I, Fidock DA. Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes. The Journal of Infectious Diseases. 203: 228-36. PMID 21288823 DOI: 10.1093/Infdis/Jiq036 |
0.466 |
|
| 2011 |
Coppi A, Natarajan R, Pradel G, Bennett BL, James ER, Roggero MA, Corradin G, Persson C, Tewari R, Sinnis P. The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host. The Journal of Experimental Medicine. 208: 341-56. PMID 21262960 DOI: 10.1084/Jem.20101488 |
0.762 |
|
| 2010 |
Bennett BL, Sinnis P. What can we learn from an unnatural immune response? Trends in Parasitology. 26: 319-21. PMID 20430697 DOI: 10.1016/J.Pt.2010.02.011 |
0.76 |
|
| 2010 |
Kortagere S, Welsh WJ, Morrisey JM, Daly T, Ejigiri I, Sinnis P, Vaidya AB, Bergman LW. Structure-based design of novel small-molecule inhibitors of Plasmodium falciparum. Journal of Chemical Information and Modeling. 50: 840-9. PMID 20426475 DOI: 10.1021/Ci100039K |
0.775 |
|
| 2009 |
Mwakingwe A, Ting LM, Hochman S, Chen J, Sinnis P, Kim K. Noninvasive real-time monitoring of liver-stage development of bioluminescent Plasmodium parasites. The Journal of Infectious Diseases. 200: 1470-8. PMID 19811100 DOI: 10.1086/606115 |
0.492 |
|
| 2009 |
Ejigiri I, Sinnis P. Plasmodium sporozoite-host interactions from the dermis to the hepatocyte. Current Opinion in Microbiology. 12: 401-7. PMID 19608456 DOI: 10.1016/J.Mib.2009.06.006 |
0.796 |
|
| 2009 |
Hobbs CV, Voza T, Coppi A, Kirmse B, Marsh K, Borkowsky W, Sinnis P. HIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites. The Journal of Infectious Diseases. 199: 134-41. PMID 19032102 DOI: 10.1086/594369 |
0.435 |
|
| 2008 |
Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, ... ... Sinnis P, et al. The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host & Microbe. 4: 567-78. PMID 19064257 DOI: 10.1016/J.Chom.2008.11.001 |
0.51 |
|
| 2008 |
Belnoue E, Voza T, Costa FT, Grüner AC, Mauduit M, Rosa DS, Depinay N, Kayibanda M, Vigário AM, Mazier D, Snounou G, Sinnis P, Rénia L. Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage. Journal of Immunology (Baltimore, Md. : 1950). 181: 8552-8. PMID 19050274 DOI: 10.4049/Jimmunol.181.12.8552 |
0.503 |
|
| 2008 |
Ting LM, Gissot M, Coppi A, Sinnis P, Kim K. Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nature Medicine. 14: 954-8. PMID 18758447 DOI: 10.1038/Nm.1867 |
0.461 |
|
| 2008 |
Sinnis P, Zavala F. The skin stage of malaria infection: biology and relevance to the malaria vaccine effort. Future Microbiology. 3: 275-8. PMID 18505393 DOI: 10.2217/17460913.3.3.275 |
0.527 |
|
| 2008 |
Sinnis P, Ernst JD. CO-opting the host HO-1 pathway in tuberculosis and malaria. Cell Host & Microbe. 3: 277-9. PMID 18474353 DOI: 10.1016/J.Chom.2008.04.009 |
0.481 |
|
| 2008 |
Gissot M, Ting LM, Daly TM, Bergman LW, Sinnis P, Kim K. High mobility group protein HMGB2 is a critical regulator of plasmodium oocyst development. The Journal of Biological Chemistry. 283: 17030-8. PMID 18400754 DOI: 10.1074/Jbc.M801637200 |
0.427 |
|
| 2008 |
Moreira CK, Templeton TJ, Lavazec C, Hayward RE, Hobbs CV, Kroeze H, Janse CJ, Waters AP, Sinnis P, Coppi A. The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cellular Microbiology. 10: 1505-16. PMID 18346224 DOI: 10.1111/J.1462-5822.2008.01143.X |
0.453 |
|
| 2007 |
Grüner AC, Mauduit M, Tewari R, Romero JF, Depinay N, Kayibanda M, Lallemand E, Chavatte JM, Crisanti A, Sinnis P, Mazier D, Corradin G, Snounou G, Rénia L. Sterile protection against malaria is independent of immune responses to the circumsporozoite protein. Plos One. 2: e1371. PMID 18159254 DOI: 10.1371/Journal.Pone.0001371 |
0.432 |
|
| 2007 |
Coppi A, Tewari R, Bishop JR, Bennett BL, Lawrence R, Esko JD, Billker O, Sinnis P. Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells. Cell Host & Microbe. 2: 316-27. PMID 18005753 DOI: 10.1016/J.Chom.2007.10.002 |
0.812 |
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| 2007 |
Kelly BA, Neil SJ, McKnight A, Santos JM, Sinnis P, Jack ER, Middleton DA, Dobson CB. Apolipoprotein E-derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity. The Febs Journal. 274: 4511-25. PMID 17681018 DOI: 10.1111/J.1742-4658.2007.05981.X |
0.339 |
|
| 2007 |
Sinnis P, Coppi A, Toida T, Toyoda H, Kinoshita-Toyoda A, Xie J, Kemp MM, Linhardt RJ. Mosquito heparan sulfate and its potential role in malaria infection and transmission. The Journal of Biological Chemistry. 282: 25376-84. PMID 17597060 DOI: 10.1074/Jbc.M704698200 |
0.525 |
|
| 2007 |
Sinnis P, Coppi A. A long and winding road: the Plasmodium sporozoite's journey in the mammalian host. Parasitology International. 56: 171-8. PMID 17513164 DOI: 10.1016/J.Parint.2007.04.002 |
0.485 |
|
| 2007 |
Yamauchi LM, Coppi A, Snounou G, Sinnis P. Plasmodium sporozoites trickle out of the injection site. Cellular Microbiology. 9: 1215-22. PMID 17223931 DOI: 10.1111/J.1462-5822.2006.00861.X |
0.508 |
|
| 2006 |
Coppi A, Cabinian M, Mirelman D, Sinnis P. Antimalarial activity of allicin, a biologically active compound from garlic cloves. Antimicrobial Agents and Chemotherapy. 50: 1731-7. PMID 16641443 DOI: 10.1128/Aac.50.5.1731-1737.2006 |
0.556 |
|
| 2006 |
Engelmann S, Sinnis P, Matuschewski K. Transgenic Plasmodium berghei sporozoites expressing beta-galactosidase for quantification of sporozoite transmission. Molecular and Biochemical Parasitology. 146: 30-7. PMID 16316690 DOI: 10.1016/J.Molbiopara.2005.10.015 |
0.434 |
|
| 2005 |
Medica DL, Sinnis P. Quantitative dynamics of Plasmodium yoelii sporozoite transmission by infected anopheline mosquitoes. Infection and Immunity. 73: 4363-9. PMID 15972531 DOI: 10.1128/Iai.73.7.4363-4369.2005 |
0.44 |
|
| 2005 |
Coppi A, Pinzon-Ortiz C, Hutter C, Sinnis P. The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion. The Journal of Experimental Medicine. 201: 27-33. PMID 15630135 DOI: 10.1084/Jem.20040989 |
0.558 |
|
| 2004 |
Myung JM, Marshall P, Sinnis P. The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites. Molecular and Biochemical Parasitology. 133: 53-9. PMID 14668012 DOI: 10.1016/J.Molbiopara.2003.09.002 |
0.372 |
|
| 2002 |
Sinnis P, Febbraio M. Plasmodium yoelii sporozoites infect CD36-deficient mice. Experimental Parasitology. 100: 12-6. PMID 11971649 DOI: 10.1006/Expr.2001.4676 |
0.32 |
|
| 2001 |
Pinzon-Ortiz C, Friedman J, Esko J, Sinnis P. The Binding of the Circumsporozoite Protein to Cell Surface Heparan Sulfate Proteoglycans is Required for Plasmodium Sporozoite Attachment to Target Cells Journal of Biological Chemistry. 276: 26784-26791. PMID 11352923 DOI: 10.1074/Jbc.M104038200 |
0.438 |
|
| 2000 |
Marshall P, Rohlmann A, Nussenzweig V, Herz J, Sinnis P. Plasmodium sporozoites invade cells with targeted deletions in the LDL receptor related protein Molecular and Biochemical Parasitology. 106: 293-298. PMID 10699258 DOI: 10.1016/S0166-6851(99)00210-8 |
0.417 |
|
| 1998 |
Sinnis P. An immunoradiometric assay for the quantification of Plasmodium sporozoite invasion of HepG2 cells Journal of Immunological Methods. 221: 17-23. PMID 9894894 DOI: 10.1016/S0022-1759(98)00151-3 |
0.541 |
|
| 1998 |
Gantt SM, Myung JM, Briones MR, Li WD, Corey EJ, Omura S, Nussenzweig V, Sinnis P. Proteasome inhibitors block development of Plasmodium spp. Antimicrobial Agents and Chemotherapy. 42: 2731-8. PMID 9756786 DOI: 10.1128/Aac.42.10.2731 |
0.494 |
|
| 1997 |
Sidjanski SP, Vanderberg JP, Sinnis P. Anopheles stephensi salivary glands bear receptors for region I of the circumsporozoite protein of Plasmodium falciparum Molecular and Biochemical Parasitology. 90: 33-41. PMID 9497030 DOI: 10.1016/S0166-6851(97)00124-2 |
0.415 |
|
| 1997 |
Gantt SM, Clavijo P, Bai X, Esko JD, Sinnis P. Cell adhesion to a motif shared by the malaria circumsporozoite protein and thrombospondin is mediated by its glycosaminoglycan-binding region and not by CSVTCG. The Journal of Biological Chemistry. 272: 19205-13. PMID 9235912 DOI: 10.1074/Jbc.272.31.19205 |
0.367 |
|
| 1997 |
Sinnis P, Sim BKL. Cell invasion by the vertebrate stages of Plasmodium Trends in Microbiology. 5: 52-58. PMID 9108930 DOI: 10.1016/S0966-842X(97)84657-4 |
0.49 |
|
| 1996 |
Sinnis P, Willnow TT, Briones MRS, Herz J, Nussenzweig V. Remnant lipoproteins inhibits malaria sporozoite invasion of hepatocytes Journal of Experimental Medicine. 184: 945-954. PMID 9064354 DOI: 10.1084/Jem.184.3.945 |
0.431 |
|
| 1996 |
Frevert U, Sinnis P, Esko JD, Nussenzweig V. Cell surface glycosaminoglycans are not obligatory for Plasmodium berghei sporozoite invasion in vitro Molecular and Biochemical Parasitology. 76: 257-266. PMID 8920011 DOI: 10.1016/0166-6851(95)02563-4 |
0.448 |
|
| 1996 |
Sinnis P. The malaria sporozoite's journey into the liver Infectious Agents and Disease. 5: 182-189. PMID 8805080 |
0.437 |
|
| 1996 |
Sinnis P. Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes Journal of Investigative Medicine. 44. |
0.323 |
|
| 1994 |
Cerami C, Frevert U, Sinnis P, Takacs B, Nussenzweig V. Rapid clearance of malaria circumsporozoite protein (CS) by hepatocytes Journal of Experimental Medicine. 179: 695-701. PMID 8294876 DOI: 10.1084/Jem.179.2.695 |
0.405 |
|
| 1994 |
Sinnis P, Clavijo P, Fenyö D, Chait BT, Cerami C, Nussenzweig V. Structural and functional properties of region II-plus of the malaria circumsporozoite protein Journal of Experimental Medicine. 180: 297-306. PMID 8006589 DOI: 10.1084/Jem.180.1.297 |
0.453 |
|
| 1993 |
Frevert U, Sinnis P, Cerami C, Shreffler W, Takacs B, Nussenzweig V. Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. The Journal of Experimental Medicine. 177: 1287-98. PMID 8478608 DOI: 10.1084/Jem.177.5.1287 |
0.418 |
|
| 1992 |
Cerami C, Frevert U, Sinnis P, Takacs B, Clavijo P, Santos MJ, Nussenzweig V. The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of plasmodium falciparum sporozoites Cell. 70: 1021-1033. PMID 1326407 DOI: 10.1016/0092-8674(92)90251-7 |
0.397 |
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