| Year |
Citation |
Score |
| 2024 |
Touvier T, Veneri FA, Claessens A, Ferri C, Mastrangelo R, Sorgiati N, Bianchi F, Valenzano S, Del Carro U, Rivellini C, Duong P, Shy ME, Kelly JW, Svaren J, Wiseman RL, et al. Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B. Biorxiv : the Preprint Server For Biology. PMID 38352425 DOI: 10.1101/2024.01.31.577760 |
0.388 |
|
| 2024 |
Scherer SS, Svaren J. Peripheral Nervous System (PNS) Myelin Diseases. Cold Spring Harbor Perspectives in Biology. PMID 38253417 DOI: 10.1101/cshperspect.a041376 |
0.382 |
|
| 2023 |
Khullar S, Huang X, Ramesh R, Svaren J, Wang D. NetREm: Network Regression Embeddings reveal cell-type transcription factor coordination for gene regulation. Biorxiv : the Preprint Server For Biology. PMID 37961577 DOI: 10.1101/2023.10.25.563769 |
0.405 |
|
| 2023 |
Pipis M, Won S, Poh R, Efthymiou S, Polke JM, Skorupinska M, Blake J, Rossor AM, Moran JJ, Munot P, Muntoni F, Laura M, Svaren J, Reilly MM. Post-transcriptional microRNA repression of PMP22 dose in severe Charcot-Marie-Tooth disease type 1. Brain : a Journal of Neurology. PMID 37337674 DOI: 10.1093/brain/awad203 |
0.317 |
|
| 2023 |
Duong P, Ramesh R, Schneider A, Won S, Cooper AJ, Svaren J. Modulation of Schwann cell homeostasis by the BAP1 deubiquitinase. Glia. PMID 36790040 DOI: 10.1002/glia.24351 |
0.519 |
|
| 2022 |
Veneri FA, Prada V, Mastrangelo R, Ferri C, Nobbio L, Passalacqua M, Milanesi M, Bianchi F, Del Carro U, Vallat JM, Duong P, Svaren J, Schenone A, Grandis M, D'Antonio M. A novel mouse model of CMT1B identifies hyperglycosylation as a new pathogenetic mechanism. Human Molecular Genetics. PMID 35908287 DOI: 10.1093/hmg/ddac170 |
0.33 |
|
| 2022 |
Ramesh R, Manurung Y, Ma KH, Blakely T, Won S, Ramos OM, Wyatt E, Awatramani R, Svaren J. JUN Regulation of Injury-induced Enhancers in Schwann Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35906072 DOI: 10.1523/JNEUROSCI.2533-21.2022 |
0.327 |
|
| 2022 |
Park HJ, Tsai E, Huang D, Weaver M, Frick L, Alcantara A, Moran JJ, Patzig J, Melendez-Vasquez CV, Crabtree GR, Feltri ML, Svaren J, Casaccia P. ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve. Iscience. 25: 104132. PMID 35434551 DOI: 10.1016/j.isci.2022.104132 |
0.424 |
|
| 2021 |
Martinez NJ, Braisted JC, Dranchak PK, Moran JJ, Larson H, Queme B, Pak E, Dutra A, Rai G, Cheng KC, Svaren J, Inglese J. Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for Gene-Dosage Disorder Drug Discovery. Acs Pharmacology & Translational Science. 4: 1422-1436. PMID 34423274 DOI: 10.1021/acsptsci.1c00110 |
0.421 |
|
| 2021 |
Duong P, Ma KH, Ramesh R, Moran JJ, Won S, Svaren J. H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve. The Journal of Biological Chemistry. 100852. PMID 34090875 DOI: 10.1016/j.jbc.2021.100852 |
0.346 |
|
| 2021 |
Wagstaff LJ, Gomez-Sanchez JA, Fazal SV, Otto GW, Kilpatrick AM, Michael K, Wong LY, Ma KH, Turmaine M, Svaren J, Gordon T, Arthur-Farraj P, Velasco-Aviles S, Cabedo H, Benito C, et al. Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun. Elife. 10. PMID 33475496 DOI: 10.7554/eLife.62232 |
0.352 |
|
| 2020 |
Lupo V, Won S, Frasquet M, Schnitzler MS, Komath SS, Pascual-Pascual SI, Espinós C, Svaren J, Sevilla T. Bi-allelic mutations in EGR2 cause autosomal recessive demyelinating neuropathy by disrupting the EGR2-NAB complex. European Journal of Neurology. PMID 32896048 DOI: 10.1111/Ene.14512 |
0.388 |
|
| 2020 |
Damaschke NA, Gawdzik J, Avilla M, Yang B, Svaren J, Roopra A, Luo JH, Yu YP, Keles S, Jarrard DF. CTCF loss mediates unique DNA hypermethylation landscapes in human cancers. Clinical Epigenetics. 12: 80. PMID 32503656 DOI: 10.1186/S13148-020-00869-7 |
0.343 |
|
| 2020 |
Pantera H, Hu B, Moiseev D, Dunham C, Rashid J, Moran JJ, Krentz K, Rubinstein CD, Won S, Li J, Svaren J. Pmp22 Super-enhancer Deletion Causes Tomacula Formation and Conduction Block in Peripheral Nerves. Human Molecular Genetics. PMID 32356557 DOI: 10.1093/Hmg/Ddaa082 |
0.605 |
|
| 2020 |
Pantera H, Shy ME, Svaren J. Regulating PMP22 expression as a dosage sensitive neuropathy gene. Brain Research. 1726: 146491. PMID 31586623 DOI: 10.1016/J.Brainres.2019.146491 |
0.517 |
|
| 2019 |
Wang H, Davison M, Wang K, Xia TH, Kramer M, Call K, Luo J, Wu X, Zuccarino R, Bacon C, Bai Y, Moran JJ, Gutmann L, Feely SME, Grider T, ... ... Svaren J, et al. Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A. Annals of Clinical and Translational Neurology. PMID 31833243 DOI: 10.1002/Acn3.50965 |
0.309 |
|
| 2019 |
Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, et al. Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Human Molecular Genetics. 28: 2282. PMID 31220267 DOI: 10.1093/hmg/ddz037 |
0.351 |
|
| 2019 |
Tao F, Beecham GW, Rebelo AP, Blanton SH, Moran JJ, Lopez-Anido C, Svaren J, Abreu L, Rizzo D, Kirk CA, Wu X, Feely S, Verhamme C, Saporta MA, Herrmann DN, et al. Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Journal of Neuromuscular Diseases. PMID 30958311 DOI: 10.3233/Jnd-190377 |
0.313 |
|
| 2019 |
Svaren J, Moran JJ, Wu X, Zuccarino R, Bacon C, Bai Y, Ramesh R, Gutmann L, Anderson DM, Pavelec D, Shy ME. Schwann Cell Transcript Biomarkers for Hereditary Neuropathy Skin Biopsies. Annals of Neurology. PMID 30945774 DOI: 10.1002/Ana.25480 |
0.39 |
|
| 2019 |
Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, et al. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Human Molecular Genetics. PMID 30668730 DOI: 10.1093/hmg/ddz021 |
0.351 |
|
| 2018 |
Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Markus Schwab H, Nave K, et al. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Human Molecular Genetics. PMID 30535360 DOI: 10.1093/Hmg/Ddy420 |
0.533 |
|
| 2018 |
Ma KH, Duong P, Moran JJ, Junaidi N, Svaren J. Polycomb repression regulates Schwann cell proliferation and axon regeneration after nerve injury. Glia. PMID 30306639 DOI: 10.1002/Glia.23500 |
0.543 |
|
| 2018 |
Pantera H, Moran JJ, Hung HA, Pak E, Dutra A, Svaren J. Regulation of the neuropathy-associated Pmp22 gene by a distal super-enhancer. Human Molecular Genetics. PMID 29771329 DOI: 10.1093/Hmg/Ddy191 |
0.857 |
|
| 2018 |
Bai Y, Wu X, Brennan KM, Wang DS, D'Antonio M, Moran J, Svaren J, Shy ME. Myelin protein zero mutations and the unfolded protein response in Charcot Marie Tooth disease type 1B. Annals of Clinical and Translational Neurology. 5: 445-455. PMID 29687021 DOI: 10.1002/Acn3.543 |
0.316 |
|
| 2018 |
Dranchak P, Moran JJ, MacArthur R, Lopez-Anido C, Inglese J, Svaren J. Genome-Edited Cell Lines for High-Throughput Screening. Methods in Molecular Biology (Clifton, N.J.). 1755: 1-17. PMID 29671259 DOI: 10.1007/978-1-4939-7724-6_1 |
0.408 |
|
| 2018 |
Lin HP, Oksuz I, Svaren J, Awatramani R. Egr2-dependent microRNA-138 is dispensable for peripheral nerve myelination. Scientific Reports. 8: 3817. PMID 29491350 DOI: 10.1038/S41598-018-22010-8 |
0.393 |
|
| 2018 |
Muhammad AKMG, Kim K, Epifantseva I, Aghamaleky-Sarvestany A, Simpkinson ME, Carmona S, Landeros J, Bell S, Svaren J, Baloh RH. Cell transplantation strategies for acquired and inherited disorders of peripheral myelin. Annals of Clinical and Translational Neurology. 5: 186-200. PMID 29468179 DOI: 10.1002/Acn3.517 |
0.388 |
|
| 2018 |
Ma KH, Svaren J. Epigenetic Control of Schwann Cells. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858417751112. PMID 29307265 DOI: 10.1177/1073858417751112 |
0.528 |
|
| 2017 |
Zhao HT, Damle S, Ikeda-Lee K, Kuntz S, Li J, Mohan A, Kim A, Hung G, Scheideler MA, Scherer SS, Svaren J, Swayze EE, Kordasiewicz HB. PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models. The Journal of Clinical Investigation. PMID 29202483 DOI: 10.1172/Jci96499 |
0.406 |
|
| 2017 |
Duncan ID, Bugiani M, Radcliff AB, Moran JJ, Lopez-Anido C, Duong P, August BK, Wolf NI, van der Knaap MS, Svaren J. A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination. Annals of Neurology. PMID 28393430 DOI: 10.1002/Ana.24930 |
0.356 |
|
| 2016 |
Ma KH, Svaren J. Epigenomic reprogramming in peripheral nerve injury. Neural Regeneration Research. 11: 1930-1931. PMID 28197188 DOI: 10.4103/1673-5374.197133 |
0.36 |
|
| 2016 |
Rodríguez-Molina JF, Lopez-Anido C, Ma KH, Zhang C, Olson T, Muth KN, Weider M, Svaren J. Dual specificity phosphatase 15 regulates Erk activation in Schwann cells. Journal of Neurochemistry. PMID 27891578 DOI: 10.1111/Jnc.13911 |
0.609 |
|
| 2016 |
Gopinath C, Law WD, Rodríguez-Molina JF, Prasad AB, Song L, Crawford GE, Mullikin JC, Svaren J, Antonellis A. Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation. Bmc Genomics. 17: 887. PMID 27821050 DOI: 10.1186/S12864-016-3167-3 |
0.598 |
|
| 2016 |
Ma KH, Hung HA, Svaren J. Epigenomic Regulation of Schwann Cell Reprogramming in Peripheral Nerve Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9135-47. PMID 27581455 DOI: 10.1523/Jneurosci.1370-16.2016 |
0.814 |
|
| 2016 |
Fogarty EA, Brewer MH, Rodriguez-Molina JF, Law WD, Ma KH, Steinberg NM, Svaren J, Antonellis A. SOX10 Regulates an Alternative Promoter at the Charcot-Marie-Tooth Disease Locus MTMR2. Human Molecular Genetics. PMID 27466180 DOI: 10.1093/Hmg/Ddw233 |
0.575 |
|
| 2016 |
Lopez-Anido C, Poitelon Y, Gopinath C, Moran JJ, Ma KH, Law WD, Antonellis A, Feltri ML, Svaren J. Tead1 regulates the expression of Peripheral Myelin Protein 22 during Schwann cell development. Human Molecular Genetics. PMID 27288457 DOI: 10.1093/Hmg/Ddw158 |
0.643 |
|
| 2016 |
Poitelon Y, Lopez-Anido C, Catignas K, Berti C, Palmisano M, Williamson C, Ameroso D, Abiko K, Hwang Y, Gregorieff A, Wrana JL, Asmani M, Zhao R, Sim FJ, Wrabetz L, ... Svaren J, et al. YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells. Nature Neuroscience. PMID 27273766 DOI: 10.1038/Nn.4316 |
0.549 |
|
| 2016 |
Damaschke NA, Yang B, Montgomery A, Svaren J, Roopra A, Luo J, Keles S, Jarrard D. Abstract 4434: CTCF acts as a master regulator to direct epigenetic events important for tumor development and progression Cancer Research. 76: 4434-4434. DOI: 10.1158/1538-7445.Am2016-4434 |
0.389 |
|
| 2015 |
Ma KH, Hung HA, Srinivasan R, Xie H, Orkin SH, Svaren J. Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8640-52. PMID 26041929 DOI: 10.1523/Jneurosci.2257-14.2015 |
0.86 |
|
| 2015 |
Lopez-Anido C, Sun G, Koenning M, Srinivasan R, Hung HA, Emery B, Keles S, Svaren J. Differential Sox10 genomic occupancy in myelinating glia. Glia. PMID 25974668 DOI: 10.1002/Glia.22855 |
0.86 |
|
| 2015 |
Hung HA, Sun G, Keles S, Svaren J. Dynamic regulation of Schwann cell enhancers after peripheral nerve injury. The Journal of Biological Chemistry. 290: 6937-50. PMID 25614629 DOI: 10.1074/Jbc.M114.622878 |
0.836 |
|
| 2015 |
Romens SE, McDonald J, Svaren J, Pollak SD. Associations between early life stress and gene methylation in children. Child Development. 86: 303-9. PMID 25056599 DOI: 10.1111/Cdev.12270 |
0.34 |
|
| 2015 |
Lopez-Anido C, Sun G, Koenning M, Srinivasan R, Hung HA, Emery B, Keles S, Svaren J. Differential Sox10 genomic occupancy in myelinating glia Glia. DOI: 10.1002/glia.22855 |
0.795 |
|
| 2014 |
Sun G, Srinivasan R, Lopez-Anido C, Hung HA, Svaren J, Kele? S. In silico pooling of ChIP-seq control experiments. Plos One. 9: e109691. PMID 25380244 DOI: 10.1371/Journal.Pone.0109691 |
0.762 |
|
| 2014 |
Inglese J, Dranchak P, Moran JJ, Jang SW, Srinivasan R, Santiago Y, Zhang L, Guha R, Martinez N, MacArthur R, Cost GJ, Svaren J. Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease. Acs Chemical Biology. 9: 2594-602. PMID 25188731 DOI: 10.1021/Cb5005492 |
0.78 |
|
| 2014 |
Svaren J. MicroRNA and transcriptional crosstalk in myelinating glia. Neurochemistry International. 77: 50-57. PMID 24979526 DOI: 10.1016/J.Neuint.2014.06.010 |
0.589 |
|
| 2014 |
Brewer MH, Ma KH, Beecham GW, Gopinath C, Baas F, Choi BO, Reilly MM, Shy ME, Züchner S, Svaren J, Antonellis A. Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2. Human Molecular Genetics. 23: 5171-87. PMID 24833716 DOI: 10.1093/Hmg/Ddu240 |
0.553 |
|
| 2014 |
Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger-Davis SM, Lee MH, Svaren J, Miyamoto S, Jarrard DF. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-κB activation. Plos One. 9: e88052. PMID 24558376 DOI: 10.1371/Journal.Pone.0088052 |
0.403 |
|
| 2014 |
Kim EH, Gasper DJ, Lee SH, Plisch EH, Svaren J, Suresh M. Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 192: 985-95. PMID 24367030 DOI: 10.4049/Jimmunol.1302378 |
0.346 |
|
| 2014 |
Pemberton TJ, Choi S, Mayer JA, Li FY, Gokey N, Svaren J, Safra N, Bannasch DL, Sullivan K, Breuhaus B, Patel PI, Duncan ID. A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination. Glia. 62: 39-51. PMID 24272703 DOI: 10.1002/Glia.22582 |
0.82 |
|
| 2013 |
Bujalka H, Koenning M, Jackson S, Perreau VM, Pope B, Hay CM, Mitew S, Hill AF, Lu QR, Wegner M, Srinivasan R, Svaren J, Willingham M, Barres BA, Emery B. MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. Plos Biology. 11: e1001625. PMID 23966833 DOI: 10.1371/Journal.Pbio.1001625 |
0.598 |
|
| 2012 |
Oliver SS, Musselman CA, Srinivasan R, Svaren JP, Kutateladze TG, Denu JM. Multivalent recognition of histone tails by the PHD fingers of CHD5. Biochemistry. 51: 6534-44. PMID 22834704 DOI: 10.1021/Bi3006972 |
0.347 |
|
| 2012 |
Jang SW, Lopez-Anido C, MacArthur R, Svaren J, Inglese J. Identification of drug modulators targeting gene-dosage disease CMT1A Acs Chemical Biology. 7: 1205-1213. PMID 22530759 DOI: 10.1021/Cb300048D |
0.803 |
|
| 2012 |
Srinivasan R, Sun G, Keles S, Jones EA, Jang SW, Krueger C, Moran JJ, Svaren J. Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve. Nucleic Acids Research. 40: 6449-60. PMID 22492709 DOI: 10.1093/Nar/Gks313 |
0.843 |
|
| 2012 |
Hung H, Kohnken R, Svaren J. The Nucleosome Remodeling and Deacetylase Chromatin Remodeling (NuRD) Complex Is Required for Peripheral Nerve Myelination The Journal of Neuroscience. 32: 1517-1527. PMID 22302795 DOI: 10.1523/Jneurosci.2895-11.2012 |
0.856 |
|
| 2012 |
Jones EA, Brewer MH, Srinivasan R, Krueger C, Sun G, Charney KN, Keles S, Antonellis A, Svaren J. Distal enhancers upstream of the Charcot-Marie-Tooth type 1A disease gene PMP22. Human Molecular Genetics. 21: 1581-91. PMID 22180461 DOI: 10.1093/Hmg/Ddr595 |
0.597 |
|
| 2012 |
Gokey NG, Srinivasan R, Lopez-Anido C, Krueger C, Svaren J. Developmental regulation of microRNA expression in Schwann cells. Molecular and Cellular Biology. 32: 558-68. PMID 22064487 DOI: 10.1128/Mcb.06270-11 |
0.8 |
|
| 2012 |
Hodonsky CJ, Kleinbrink EL, Charney KN, Prasad M, Bessling SL, Jones EA, Srinivasan R, Svaren J, McCallion AS, Antonellis A. SOX10 regulates expression of the SH3-domain kinase binding protein 1 (Sh3kbp1) locus in Schwann cells via an alternative promoter. Molecular and Cellular Neurosciences. 49: 85-96. PMID 22037207 DOI: 10.1016/J.Mcn.2011.10.004 |
0.573 |
|
| 2011 |
Gokey NG, Lopez-Anido C, Gillian-Daniel AL, Svaren J. Early growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression. The Journal of Biological Chemistry. 286: 29501-10. PMID 21712389 DOI: 10.1074/Jbc.M111.263509 |
0.793 |
|
| 2011 |
Prasad MK, Reed X, Gorkin DU, Cronin JC, McAdow AR, Chain K, Hodonsky CJ, Jones EA, Svaren J, Antonellis A, Johnson SL, Loftus SK, Pavan WJ, McCallion AS. SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer. Bmc Developmental Biology. 11: 40. PMID 21672228 DOI: 10.1186/1471-213X-11-40 |
0.462 |
|
| 2011 |
Jagalur NB, Ghazvini M, Mandemakers W, Driegen S, Maas A, Jones EA, Jaegle M, Grosveld F, Svaren J, Meijer D. Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8585-94. PMID 21653862 DOI: 10.1523/Jneurosci.0659-11.2011 |
0.596 |
|
| 2011 |
Chen Y, Wang H, Yoon SO, Xu X, Hottiger MO, Svaren J, Nave KA, Kim HA, Olson EN, Lu QR. HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nature Neuroscience. 14: 437-41. PMID 21423191 DOI: 10.1038/Nn.2780 |
0.529 |
|
| 2011 |
Jones EA, Lopez-Anido C, Srinivasan R, Krueger C, Chang LW, Nagarajan R, Svaren J. Regulation of the PMP22 gene through an intronic enhancer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4242-50. PMID 21411665 DOI: 10.1523/Jneurosci.5893-10.2011 |
0.623 |
|
| 2010 |
He Y, Kim JY, Dupree J, Tewari A, Melendez-Vasquez C, Svaren J, Casaccia P. Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination. Nature Neuroscience. 13: 1472-80. PMID 21057508 DOI: 10.1038/Nn.2686 |
0.58 |
|
| 2010 |
Jang SW, Srinivasan R, Jones EA, Sun G, Keles S, Krueger C, Chang LW, Nagarajan R, Svaren J. Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes. Journal of Neurochemistry. 115: 1409-20. PMID 21044070 DOI: 10.1111/J.1471-4159.2010.07045.X |
0.857 |
|
| 2009 |
Jang SW, Svaren J. Induction of myelin protein zero by early growth response 2 through upstream and intragenic elements. The Journal of Biological Chemistry. 284: 20111-20. PMID 19487693 DOI: 10.1074/Jbc.M109.022426 |
0.845 |
|
| 2008 |
Svaren J, Meijer D. The molecular machinery of myelin gene transcription in Schwann cells Glia. 56: 1541-1551. PMID 18803322 DOI: 10.1002/Glia.20767 |
0.575 |
|
| 2008 |
Fu VX, Dobosy JR, Desotelle JA, Almassi N, Ewald JA, Srinivasan R, Berres M, Svaren J, Weindruch R, Jarrard DF. Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate. Cancer Research. 68: 6797-802. PMID 18701505 DOI: 10.1158/0008-5472.Can-08-1714 |
0.323 |
|
| 2008 |
Dobosy JR, Fu VX, Desotelle JA, Srinivasan R, Kenowski ML, Almassi N, Weindruch R, Svaren J, Jarrard DF. A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate. The Prostate. 68: 1187-95. PMID 18459101 DOI: 10.1002/Pros.20782 |
0.307 |
|
| 2008 |
Mager GM, Ward RM, Srinivasan R, Jang SW, Wrabetz L, Svaren J. Active gene repression by the Egr2.NAB complex during peripheral nerve myelination. The Journal of Biological Chemistry. 283: 18187-97. PMID 18456662 DOI: 10.1074/Jbc.M803330200 |
0.842 |
|
| 2008 |
Tureyen K, Brooks N, Bowen K, Svaren J, Vemuganti R. Transcription factor early growth response-1 induction mediates inflammatory gene expression and brain damage following transient focal ischemia. Journal of Neurochemistry. 105: 1313-24. PMID 18208539 DOI: 10.1111/J.1471-4159.2008.05233.X |
0.329 |
|
| 2007 |
Jones EA, Jang SW, Mager GM, Chang LW, Srinivasan R, Gokey NG, Ward RM, Nagarajan R, Svaren J. Interactions of Sox10 and Egr2 in myelin gene regulation. Neuron Glia Biology. 3: 377-87. PMID 18634568 DOI: 10.1017/S1740925X08000173 |
0.806 |
|
| 2007 |
Srinivasan R, Jang SW, Ward RM, Sachdev S, Ezashi T, Svaren J. Differential regulation of NAB corepressor genes in Schwann cells. Bmc Molecular Biology. 8: 117. PMID 18096076 DOI: 10.1186/1471-2199-8-117 |
0.825 |
|
| 2007 |
Shamim M, Nanjappa SG, Singh A, Plisch EH, LeBlanc SE, Walent J, Svaren J, Seroogy C, Suresh M. Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 T cells without affecting functional avidity. Journal of Immunology (Baltimore, Md. : 1950). 179: 7233-43. PMID 18025165 DOI: 10.4049/Jimmunol.179.11.7233 |
0.744 |
|
| 2007 |
Muir P, Schaefer SL, Manley PA, Svaren JP, Oldenhoff WE, Hao Z. Expression of immune response genes in the stifle joint of dogs with oligoarthritis and degenerative cranial cruciate ligament rupture Veterinary Immunology and Immunopathology. 119: 214-221. PMID 17629954 DOI: 10.1016/J.Vetimm.2007.05.016 |
0.309 |
|
| 2007 |
LeBlanc SE, Ward RM, Svaren J. Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. Molecular and Cellular Biology. 27: 3521-9. PMID 17325040 DOI: 10.1128/Mcb.01689-06 |
0.839 |
|
| 2006 |
Jang SW, LeBlanc SE, Roopra A, Wrabetz L, Svaren J. In vivo detection of Egr2 binding to target genes during peripheral nerve myelination. Journal of Neurochemistry. 98: 1678-87. PMID 16923174 DOI: 10.1111/J.1471-4159.2006.04069.X |
0.855 |
|
| 2006 |
Srinivasan R, Mager GM, Ward RM, Mayer J, Svaren J. NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex. The Journal of Biological Chemistry. 281: 15129-37. PMID 16574654 DOI: 10.1074/Jbc.M600775200 |
0.813 |
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| 2006 |
LeBlanc SE, Jang SW, Ward RM, Wrabetz L, Svaren J. Direct regulation of myelin protein zero expression by the Egr2 transactivator. The Journal of Biological Chemistry. 281: 5453-60. PMID 16373334 DOI: 10.1074/Jbc.M512159200 |
0.855 |
|
| 2005 |
Le N, Nagarajan R, Wang JY, Svaren J, LaPash C, Araki T, Schmidt RE, Milbrandt J. Nab proteins are essential for peripheral nervous system myelination. Nature Neuroscience. 8: 932-40. PMID 16136673 DOI: 10.1038/Nn1490 |
0.578 |
|
| 2005 |
Leblanc SE, Srinivasan R, Ferri C, Mager GM, Gillian-Daniel AL, Wrabetz L, Svaren J. Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination. Journal of Neurochemistry. 93: 737-48. PMID 15836632 DOI: 10.1111/J.1471-4159.2005.03056.X |
0.822 |
|
| 2005 |
Fu VX, Kenowski ML, Schwarze SR, LeBlanc S, Svaren J, Jarrard DF. 252: A Loss of Insulin-Like Growth Factor-2 (IGF2) Imprinting is Modulated by CTCF Downregulation at Senescence in Human Epithelial Cells Journal of Urology. 173: 69-69. DOI: 10.1016/S0022-5347(18)34517-8 |
0.744 |
|
| 2004 |
Fu VX, Schwarze SR, Kenowski ML, Leblanc S, Svaren J, Jarrard DF. A loss of insulin-like growth factor-2 imprinting is modulated by CCCTC-binding factor down-regulation at senescence in human epithelial cells. The Journal of Biological Chemistry. 279: 52218-26. PMID 15471867 DOI: 10.1074/Jbc.M405015200 |
0.787 |
|
| 2004 |
Pal S, Nemeth MJ, Bodine D, Miller JL, Svaren J, Thein SL, Lowry PJ, Bresnick EH. Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1. The Journal of Biological Chemistry. 279: 31348-56. PMID 15123623 DOI: 10.1074/Jbc.M403475200 |
0.36 |
|
| 2004 |
Gillian AL, Svaren J. The Ddx20/DP103 Dead Box Protein Represses Transcriptional Activation by Egr2/Krox-20 Journal of Biological Chemistry. 279: 9056-9063. PMID 14699164 DOI: 10.1074/Jbc.M309308200 |
0.545 |
|
| 2002 |
Venken K, Di Maria E, Bellone E, Balestra P, Cassandrini D, Mandich P, De Jonghe P, Timmerman V, Svaren J. Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies. Neurogenetics. 4: 37-41. PMID 12030330 DOI: 10.1007/S10048-001-0124-2 |
0.385 |
|
| 2001 |
Nagarajan R, Svaren J, Le N, Araki T, Watson M, Milbrandt J. EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron. 30: 355-68. PMID 11394999 DOI: 10.1016/S0896-6273(01)00282-3 |
0.594 |
|
| 2001 |
Houston P, Campbell CJ, Svaren J, Milbrandt J, Braddock M. The transcriptional corepressor NAB2 blocks Egr-1-mediated growth factor activation and angiogenesis. Biochemical and Biophysical Research Communications. 283: 480-6. PMID 11327726 DOI: 10.1006/Bbrc.2001.4810 |
0.388 |
|
| 2000 |
Svaren J, Ehrig T, Abdulkadir SA, Ehrengruber MU, Watson MA, Milbrandt J. EGR1 Target Genes in Prostate Carcinoma Cells Identified by Microarray Analysis Journal of Biological Chemistry. 275: 38524-38531. PMID 10984481 DOI: 10.1074/Jbc.M005220200 |
0.427 |
|
| 2000 |
Sevetson BR, Svaren J, Milbrandt J. A Novel Activation Function for NAB Proteins in EGR-dependent Transcription of the Luteinizing Hormone β Gene Journal of Biological Chemistry. 275: 9749-9757. PMID 10734128 DOI: 10.1074/Jbc.275.13.9749 |
0.478 |
|
| 2000 |
Bergh FT, Flinn EM, Svaren J, Wright AP, Hörz W. Comparison of nucleosome remodeling by the yeast transcription factor Pho4 and the glucocorticoid receptor Journal of Biological Chemistry. 275: 9035-9042. PMID 10722753 DOI: 10.1074/Jbc.275.12.9035 |
0.404 |
|
| 1999 |
Warner LE, Svaren J, Milbrandt J, Lupski JR. Functional Consequences of Mutations in the Early Growth Response 2 Gene (EGR2) Correlate with Severity of Human Myelinopathies Human Molecular Genetics. 8: 1245-1251. PMID 10369870 DOI: 10.1093/Hmg/8.7.1245 |
0.433 |
|
| 1999 |
Dorn C, Ou Q, Svaren J, Crawford PA, Sadovsky Y. Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1. The Journal of Biological Chemistry. 274: 13870-6. PMID 10318795 DOI: 10.1074/Jbc.274.20.13870 |
0.401 |
|
| 1998 |
Svaren J, Sevetson BR, Golda T, Stanton JJ, Swirnoff AH, Milbrandt J. Novel mutants of NAB corepressors enhance activation by Egr transactivators The Embo Journal. 17: 6010-6019. PMID 9774344 DOI: 10.1093/Emboj/17.20.6010 |
0.414 |
|
| 1998 |
McAndrew PC, Svaren J, Martin SR, Hörz W, Goding CR. Requirements for Chromatin Modulation and Transcription Activation by the Pho4 Acidic Activation Domain Molecular and Cellular Biology. 18: 5818-5827. PMID 9742099 DOI: 10.1128/Mcb.18.10.5818 |
0.38 |
|
| 1998 |
Qu Z, Wolfraim LA, Svaren J, Ehrengruber MU, Davidson N, Milbrandt J. The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells Journal of Cell Biology. 142: 1075-1082. PMID 9722618 DOI: 10.1083/Jcb.142.4.1075 |
0.373 |
|
| 1998 |
Swirnoff AH, Apel ED, Svaren J, Sevetson BR, Zimonjic DB, Popescu NC, Milbrandt J. Nab1, a Corepressor of NGFI-A (Egr-1), Contains an Active Transcriptional Repression Domain Molecular and Cellular Biology. 18: 512-524. PMID 9418898 DOI: 10.1128/Mcb.18.1.512 |
0.512 |
|
| 1997 |
Svaren J, Apel ED, Simburger KS, Jenkins NA, Gilbert DJ, Copeland NA, Milbrandt J. The Nab2 and Stat6 genes share a common transcription termination region. Genomics. 41: 33-9. PMID 9126479 DOI: 10.1006/Geno.1997.4609 |
0.45 |
|
| 1997 |
Svaren J, Hörz W. Transcription factors vs nucleosomes: regulation of the PH05 promoter in yeast Trends in Biochemical Sciences. 22: 93-97. PMID 9066259 DOI: 10.1016/S0968-0004(97)01001-3 |
0.384 |
|
| 1996 |
Barbaric S, Münsterkötter M, Svaren J, Hörz W. The Homeodomain Protein Pho2 and the Basic-Helix-Loop-Helix Protein Pho4 Bind DNA Cooperatively at the Yeast PHO5 Promoter Nucleic Acids Research. 24: 4479-4486. PMID 8948638 DOI: 10.1093/Nar/24.22.4479 |
0.384 |
|
| 1996 |
Svaren J, Hörz W. Regulation of gene expression by nucleosomes. Current Opinion in Genetics & Development. 6: 164-170. PMID 8722172 DOI: 10.1016/S0959-437X(96)80046-3 |
0.44 |
|
| 1996 |
Svaren J, Sevetson BR, Apel ED, Zimonjic DB, Popescu NC, Milbrandt J. NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Molecular and Cellular Biology. 16: 3545-3553. PMID 8668170 DOI: 10.1128/Mcb.16.7.3545 |
0.495 |
|
| 1995 |
Svaren J, Hörz W. Interplay between nucleosomes and transcription factors at the yeastPHO5promoter Seminars in Cell Biology. 6: 177-183. PMID 8562909 DOI: 10.1006/Scel.1995.0025 |
0.4 |
|
| 1994 |
Svaren J, Schmitz J, Hörz W. The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter. The Embo Journal. 13: 4856-4862. DOI: 10.1002/J.1460-2075.1994.Tb06812.X |
0.389 |
|
| 1994 |
Venter U, Svaren J, Schmitz J, Schmid A, Hörz W. A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter. The Embo Journal. 13: 4848-4855. DOI: 10.1002/J.1460-2075.1994.Tb06811.X |
0.409 |
|
| 1993 |
Svaren J, Hörz W. Histones, nucleosomes and transcription. Current Opinion in Genetics & Development. 3: 219-225. PMID 8389216 DOI: 10.1016/0959-437X(93)90026-L |
0.426 |
|
| 1990 |
Svaren J, Chalkley R. The structure and assembly of active chromatin. Trends in Genetics : Tig. 6: 52-6. PMID 2186529 DOI: 10.1016/0168-9525(90)90074-G |
0.364 |
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