Harris Perlman - Publications

Affiliations: 
Saint Louis University, St. Louis, MO, United States 
Area:
Immunology, Microbiology Biology, Molecular Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Tsai F, Homan PJ, Agrawal H, Misharin AV, Abdala-Valencia H, Haines GK, Dominguez S, Bloomfield CL, Saber R, Chang A, Mohan C, Hutcheson J, Davidson A, Budinger GRS, Bouillet P, ... ... Perlman H, et al. Bim suppresses the development of SLE by limiting myeloid inflammatory responses. The Journal of Experimental Medicine. PMID 29114065 DOI: 10.1084/jem.20170479  1
2017 MacLauchlan S, Zuriaga MA, Fuster JJ, Cuda CM, Jonason J, Behzadi F, Duffen JP, Haines GK, Aprahamian T, Perlman H, Walsh K. Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis. Arthritis Research & Therapy. 19: 166. PMID 28724439 DOI: 10.1186/s13075-017-1375-0  0.52
2017 Huang QQ, Birket R, Doyle RE, Haines GK, Perlman H, Shi B, Homan P, Xing L, Pope RM. Increased F4/80(hi) macrophages is associated with suppression of serum transfer induced arthritis in mice with Flip reduced in myeloid cells. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28511285 DOI: 10.1002/art.40151  0.52
2016 Cuda CM, Pope RM, Perlman H. The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases. Nature Reviews. Rheumatology. 12: 543-58. PMID 27549026 DOI: 10.1038/nrrheum.2016.132  1
2016 Archer AM, Saber R, Rose S, Shaffer A, Misharin AV, Tsai F, Haines Iii GK, Dominguez S, Eren M, Vaughan DE, Cuda CM, Perlman H. ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model. Journal of Translational Medicine. 14: 170. PMID 27287704 DOI: 10.1186/s12967-016-0912-y  1
2016 Chiu S, Fernandez R, Subramanian V, Sun H, DeCamp MM, Kreisel D, Perlman H, Budinger GR, Mohanakumar T, Bharat A. Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 27194786 DOI: 10.4049/jimmunol.1502539  1
2015 Cuda CM, Misharin AV, Khare S, Saber R, Tsai F, Archer AM, Homan PJ, Haines GK, Hutcheson J, Dorfleutner A, Budinger GR, Stehlik C, Perlman H. Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner. Arthritis Research & Therapy. 17: 291. PMID 26471282 DOI: 10.1186/s13075-015-0794-z  1
2015 Saber R, Liu K, Ferrucci L, Criqui MH, Zhao L, Tian L, Guralnik JM, Liao Y, Domanchuk K, Kibbe MR, Green D, Perlman H, McDermott MM. Ischemia-related changes in circulating stem and progenitor cells and associated clinical characteristics in peripheral artery disease. Vascular Medicine (London, England). PMID 26324152 DOI: 10.1177/1358863X15600255  1
2015 Duffau P, Menn-Josephy H, Cuda CM, Dominguez S, Aprahamian TR, Watkins AA, Yasuda K, Monach P, Lafyatis R, Rice LM, Haines GK, Gravallese EM, Baum R, Richez C, Perlman H, et al. Interferon Regulatory Factor 5 Promotes Inflammatory Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26315890 DOI: 10.1002/art.39321  1
2015 de Almeida L, Khare S, Misharin AV, Patel R, Ratsimandresy RA, Wallin MC, Perlman H, Greaves DR, Hoffman HM, Dorfleutner A, Stehlik C. The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity. 43: 264-76. PMID 26275995 DOI: 10.1016/j.immuni.2015.07.018  1
2015 Huang QQ, Perlman H, Birkett R, Doyle R, Fang D, Haines GK, Robinson W, Datta S, Huang Z, Li QZ, Phee H, Pope RM. CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. Nature Communications. 6: 7086. PMID 25963626 DOI: 10.1038/ncomms8086  1
2015 Belmadani A, Ren D, Bhattacharyya BJ, Hope TJ, Perlman H, Miller RJ. Identification of a sustained neurogenic zone at the dorsal surface of the adult mouse hippocampus and its regulation by the chemokine SDF-1. Hippocampus. PMID 25656357 DOI: 10.1002/hipo.22428  1
2015 Morales-Nebreda LI, Rogel MR, Eisenberg JL, Hamill KJ, Soberanes S, Nigdelioglu R, Chi M, Cho T, Radigan KA, Ridge KM, Misharin AV, Woychek A, Hopkinson S, Perlman H, Mutlu GM, et al. Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 52: 503-12. PMID 25188360 DOI: 10.1165/rcmb.2014-0057OC  1
2014 Misharin AV, Cuda CM, Saber R, Turner JD, Gierut AK, Haines GK, Berdnikovs S, Filer A, Clark AR, Buckley CD, Mutlu GM, Budinger GR, Perlman H. Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice. Cell Reports. 9: 591-604. PMID 25373902 DOI: 10.1016/j.celrep.2014.09.032  1
2014 Radigan KA, Morales-Nebreda L, Soberanes S, Nicholson T, Nigdelioglu R, Cho T, Chi M, Hamanaka RB, Misharin AV, Perlman H, Budinger GR, Mutlu GM. Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages. Plos One. 9: e108138. PMID 25232724 DOI: 10.1371/journal.pone.0108138  1
2014 Cuda CM, Misharin AV, Gierut AK, Saber R, Haines GK, Hutcheson J, Hedrick SM, Mohan C, Budinger GS, Stehlik C, Perlman H. Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. Journal of Immunology (Baltimore, Md. : 1950). 192: 5548-60. PMID 24808358 DOI: 10.4049/jimmunol.1400122  1
2014 Khare S, Ratsimandresy RA, de Almeida L, Cuda CM, Rellick SL, Misharin AV, Wallin MC, Gangopadhyay A, Forte E, Gottwein E, Perlman H, Reed JC, Greaves DR, Dorfleutner A, Stehlik C. The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses. Nature Immunology. 15: 343-53. PMID 24531343 DOI: 10.1038/ni.2829  1
2014 Huang QQ, Birkett R, Koessler RE, Cuda CM, Haines GK, Jin JP, Perlman H, Pope RM. Fas signaling in macrophages promotes chronicity in K/BxN serum-induced arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 68-77. PMID 24431281 DOI: 10.1002/art.38198  1
2013 Domanchuk K, Ferrucci L, Guralnik JM, Criqui MH, Tian L, Liu K, Losordo D, Stein J, Green D, Kibbe M, Zhao L, Annex B, Perlman H, Lloyd-Jones D, Pearce W, et al. Progenitor cell release plus exercise to improve functional performance in peripheral artery disease: the PROPEL Study. Contemporary Clinical Trials. 36: 502-9. PMID 24080099 DOI: 10.1016/j.cct.2013.09.011  1
2013 Qiu Q, Zheng Z, Chang L, Zhao YS, Tan C, Dandekar A, Zhang Z, Lin Z, Gui M, Li X, Zhang T, Kong Q, Li H, Chen S, Chen A, ... ... Perlman H, et al. Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. The Embo Journal. 32: 2477-90. PMID 23942232 DOI: 10.1038/emboj.2013.183  1
2013 Rose S, Waters EA, Haney CR, Meade CT, Perlman H. High-resolution magnetic resonance imaging of ankle joints in murine arthritis discriminates inflammation and bone destruction in a quantifiable manner. Arthritis and Rheumatism. 65: 2279-89. PMID 23740612 DOI: 10.1002/art.38030  1
2013 Misharin AV, Morales-Nebreda L, Mutlu GM, Budinger GR, Perlman H. Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung. American Journal of Respiratory Cell and Molecular Biology. 49: 503-10. PMID 23672262 DOI: 10.1165/rcmb.2013-0086MA  1
2013 Huang QQ, Koessler RE, Birkett R, Perlman H, Xing L, Pope RM. TLR2 deletion promotes arthritis through reduction of IL-10. Journal of Leukocyte Biology. 93: 751-9. PMID 23446149 DOI: 10.1189/jlb.0912473  1
2013 Sena LA, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman DA, Wang CR, Schumacker PT, Licht JD, Perlman H, Bryce PJ, Chandel NS. Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity. 38: 225-36. PMID 23415911 DOI: 10.1016/j.immuni.2012.10.020  1
2013 Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, Strauss-Ayali D, Viukov S, Guilliams M, Misharin A, Hume DA, Perlman H, Malissen B, Zelzer E, Jung S. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity. 38: 79-91. PMID 23273845 DOI: 10.1016/j.immuni.2012.12.001  1
2013 Rose S, Eren M, Murphy S, Zhang H, Thaxton CS, Chowaniec J, Waters EA, Meade TJ, Vaughan DE, Perlman H. A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis. Annals of the Rheumatic Diseases. 72: 89-95. PMID 22736097 DOI: 10.1136/annrheumdis-2012-201431  1
2012 Misharin AV, Haines GK, Rose S, Gierut AK, Hotchkiss RS, Perlman H. Development of a new humanized mouse model to study acute inflammatory arthritis. Journal of Translational Medicine. 10: 190. PMID 22974474 DOI: 10.1186/1479-5876-10-190  1
2012 Huang QQ, Koessler RE, Birkett R, Dorfleutner A, Perlman H, Haines GK, Stehlik C, Nicchitta CV, Pope RM. Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis. Arthritis and Rheumatism. 64: 3638-48. PMID 22777994 DOI: 10.1002/art.34610  1
2012 Radigan KA, Urich D, Misharin AV, Chiarella SE, Soberanes S, Gonzalez A, Perlman H, Wunderink RG, Budinger GR, Mutlu GM. The effect of rosuvastatin in a murine model of influenza A infection. Plos One. 7: e35788. PMID 22536437 DOI: 10.1371/journal.pone.0035788  1
2012 Cuda CM, Agrawal H, Misharin AV, Haines GK, Hutcheson J, Weber E, Schoenfeldt JA, Mohan C, Pope RM, Perlman H. Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice. Arthritis and Rheumatism. 64: 808-20. PMID 22143975 DOI: 10.1002/art.34317  1
2012 Mavers M, Cuda CM, Misharin AV, Gierut AK, Agrawal H, Weber E, Novack DV, Haines GK, Balomenos D, Perlman H. Cyclin-dependent kinase inhibitor p21, via its C-terminal domain, is essential for resolution of murine inflammatory arthritis. Arthritis and Rheumatism. 64: 141-52. PMID 21898359 DOI: 10.1002/art.33311  0.52
2011 Urich D, Eisenberg JL, Hamill KJ, Takawira D, Chiarella SE, Soberanes S, Gonzalez A, Koentgen F, Manghi T, Hopkinson SB, Misharin AV, Perlman H, Mutlu GM, Budinger GR, Jones JC. Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury. Journal of Cell Science. 124: 2927-37. PMID 21878500 DOI: 10.1242/jcs.080911  1
2011 Sahoo S, Klychko E, Thorne T, Misener S, Schultz KM, Millay M, Ito A, Liu T, Kamide C, Agrawal H, Perlman H, Qin G, Kishore R, Losordo DW. Exosomes from human CD34(+) stem cells mediate their proangiogenic paracrine activity. Circulation Research. 109: 724-8. PMID 21835908 DOI: 10.1161/CIRCRESAHA.111.253286  1
2010 Huang QQ, Perlman H, Huang Z, Birkett R, Kan L, Agrawal H, Misharin A, Gurbuxani S, Crispino JD, Pope RM. FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis. Blood. 116: 4968-77. PMID 20724542 DOI: 10.1182/blood-2009-11-252841  1
2010 Scatizzi JC, Hutcheson J, Pope RM, Firestein GS, Koch AE, Mavers M, Smason A, Agrawal H, Haines GK, Chandel NS, Hotchkiss RS, Perlman H. Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. Arthritis and Rheumatism. 62: 441-51. PMID 20112357 DOI: 10.1002/art.27198  1
2009 Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. European Journal of Immunology. 39: 820-5. PMID 19189309 DOI: 10.1002/eji.200838683  1
2009 Peck-Palmer OM, Unsinger J, Chang KC, McDonough JS, Perlman H, McDunn JE, Hotchkiss RS. Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages. Shock (Augusta, Ga.). 31: 359-66. PMID 18838943 DOI: 10.1097/SHK.0b013e31818ba2a2  1
2008 Hutcheson J, Perlman H. BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention. Oncogene. 27: S168-75. PMID 19641502 DOI: 10.1038/onc.2009.54  1
2008 Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK, Wu T, Li QZ, Davis LS, Mohan C, Perlman H. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity. 28: 206-17. PMID 18275831 DOI: 10.1016/j.immuni.2007.12.015  1
2007 Hutcheson J, Perlman H. Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes. Immunobiology. 212: 629-36. PMID 17869640 DOI: 10.1016/j.imbio.2007.05.003  1
2007 Scatizzi JC, Hutcheson J, Bickel E, Haines GK, Perlman H. Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis. Arthritis Research & Therapy. 9: R49. PMID 17509138 DOI: 10.1186/ar2204  1
2007 Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS. Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35. PMID 17145774 DOI: 10.1128/MCB.01535-06  1
2007 Albee L, Shi B, Perlman H. Aspartic protease and caspase 3/7 activation are central for macrophage apoptosis following infection with Escherichia coli. Journal of Leukocyte Biology. 81: 229-37. PMID 17023557 DOI: 10.1189/jlb.0506358  0.32
2006 Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis. Arthritis and Rheumatism. 54: 3182-93. PMID 17009248 DOI: 10.1002/art.22133  1
2006 Woods JM, Klosowska K, Spoden DJ, Stumbo NG, Paige DJ, Scatizzi JC, Volin MV, Rao MS, Perlman H. A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis. Arthritis Research & Therapy. 8: R113. PMID 16846525 DOI: 10.1186/ar1999  1
2006 Scatizzi JC, Hutcheson J, Bickel E, Woods JM, Klosowska K, Moore TL, Haines GK, Perlman H. p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis. The American Journal of Pathology. 168: 1531-41. PMID 16651620 DOI: 10.2353/ajpath.2006.050555  1
2005 Liu H, Eksarko P, Temkin V, Haines GK, Perlman H, Koch AE, Thimmapaya B, Pope RM. Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis. Journal of Immunology (Baltimore, Md. : 1950). 175: 8337-45. PMID 16339575  0.52
2005 Coultas L, Bouillet P, Loveland KL, Meachem S, Perlman H, Adams JM, Strasser A. Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis. The Embo Journal. 24: 3963-73. PMID 16270031 DOI: 10.1038/sj.emboj.7600857  0.52
2005 Hutcheson J, Scatizzi JC, Bickel E, Brown NJ, Bouillet P, Strasser A, Perlman H. Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis. The Journal of Experimental Medicine. 201: 1949-60. PMID 15967824 DOI: 10.1084/jem.20041484  1
2004 Bai S, Liu H, Chen KH, Eksarko P, Perlman H, Moore TL, Pope RM. NF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis. Arthritis and Rheumatism. 50: 3844-55. PMID 15593196 DOI: 10.1002/art.20680  1
2004 Brown NJ, Hutcheson J, Bickel E, Scatizzi JC, Albee LD, Haines GK, Eslick J, Bradley K, Taricone E, Perlman H. Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 7584-93. PMID 15585886  1
2004 Eslick J, Scatizzi JC, Albee L, Bickel E, Bradley K, Perlman H. IL-4 and IL-10 inhibition of spontaneous monocyte apoptosis is associated with Flip upregulation. Inflammation. 28: 139-45. PMID 15527169 DOI: 10.1023/B:IFLA.0000039560.00231.cd  1
2004 Yang J, Sato K, Aprahamian T, Brown NJ, Hutcheson J, Bialik A, Perlman H, Walsh K. Endothelial overexpression of Fas ligand decreases atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1466-73. PMID 15178561 DOI: 10.1161/01.ATV.0000134402.94963.2f  1
2004 Bradley K, Scatizzi JC, Fiore S, Shamiyeh E, Koch AE, Firestein GS, Gorges LL, Kuntsman K, Pope RM, Moore TL, Han J, Perlman H. Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts. Arthritis and Rheumatism. 50: 78-87. PMID 14730602 DOI: 10.1002/art.11482  1
2003 Perlman H, Nguyen N, Liu H, Eslick J, Esser S, Walsh K, Moore TL, Pope RM. Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3. Arthritis and Rheumatism. 48: 3096-101. PMID 14613271 DOI: 10.1002/art.11302  1
2003 Yang J, Jones SP, Suhara T, Greer JJ, Ware PD, Nguyen NP, Perlman H, Nelson DP, Lefer DJ, Walsh K. Endothelial cell overexpression of fas ligand attenuates ischemia-reperfusion injury in the heart. The Journal of Biological Chemistry. 278: 15185-91. PMID 12576484 DOI: 10.1074/jbc.M211707200  1
2003 Perlman H, Bradley K, Liu H, Cole S, Shamiyeh E, Smith RC, Walsh K, Fiore S, Koch AE, Firestein GS, Haines GK, Pope RM. IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts. Journal of Immunology (Baltimore, Md. : 1950). 170: 838-45. PMID 12517948  0.52
2002 Perlman H, Liu H, Georganas C, Woods JM, Amin MA, Koch AE, Wickham T, Kovesdi I, Mano T, Walsh K, Pope RM. Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression. The Journal of Rheumatology. 29: 1593-600. PMID 12180715  1
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