Alice Prince - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Immunology, Pharmacology, Microbiology Biology, Cell Biology

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Year Citation  Score
2023 Tomlinson KL, Chen YT, Junker A, Urso A, Wong Fok Lung T, Ahn D, Hofstaedter CE, Baskota SU, Ernst RK, Prince A, Riquelme SA. Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection. Cell Metabolism. 35: 1767-1781.e6. PMID 37793346 DOI: 10.1016/j.cmet.2023.09.001  0.378
2023 Tomlinson KL, Riquelme SA, Baskota SU, Drikic M, Monk IR, Stinear TP, Lewis IA, Prince AS. Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst. Cell Reports. 42: 112064. PMID 36724077 DOI: 10.1016/j.celrep.2023.112064  0.335
2022 Urso A, Prince A. Anti-Inflammatory Metabolites in the Pathogenesis of Bacterial Infection. Frontiers in Cellular and Infection Microbiology. 12: 925746. PMID 35782110 DOI: 10.3389/fcimb.2022.925746  0.307
2022 Wong Fok Lung T, Charytonowicz D, Beaumont KG, Shah SS, Sridhar SH, Gorrie CL, Mu A, Hofstaedter CE, Varisco D, McConville TH, Drikic M, Fowler B, Urso A, Shi W, Fucich D, ... ... Prince A, et al. Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection. Cell Metabolism. PMID 35413274 DOI: 10.1016/j.cmet.2022.03.009  0.315
2021 Tomlinson KL, Prince AS, Wong Fok Lung T. Immunometabolites Drive Bacterial Adaptation to the Airway. Frontiers in Immunology. 12: 790574. PMID 34899759 DOI: 10.3389/fimmu.2021.790574  0.35
2021 Riquelme SA, Prince A. Consumption of Airway Metabolites Promotes Lung Infection. Pathogens (Basel, Switzerland). 10. PMID 34451421 DOI: 10.3390/pathogens10080957  0.353
2021 Ahn D, Bhushan G, McConville TH, Annavajhala MK, Soni RK, Wong Fok Lung T, Hofstaedter CE, Shah SS, Chong AM, Castano VG, Ernst RK, Uhlemann AC, Prince A. An acquired acyltransferase promotes Klebsiella pneumoniae ST258 respiratory infection. Cell Reports. 35: 109196. PMID 34077733 DOI: 10.1016/j.celrep.2021.109196  0.333
2021 Tomlinson KL, Lung TWF, Dach F, Annavajhala MK, Gabryszewski SJ, Groves RA, Drikic M, Francoeur NJ, Sridhar SH, Smith ML, Khanal S, Britto CJ, Sebra R, Lewis I, Uhlemann AC, ... ... Prince AS, et al. Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation. Nature Communications. 12: 1399. PMID 33658521 DOI: 10.1038/s41467-021-21718-y  0.363
2021 Shah SS, Fidock DA, Prince AS. Hemozoin Promotes Lung Inflammation via Host Epithelial Activation. Mbio. 12. PMID 33563839 DOI: 10.1128/mBio.02399-20  0.347
2020 Riquelme SA, Prince A. Airway immunometabolites fuel Pseudomonas aeruginosa infection. Respiratory Research. 21: 326. PMID 33302964 DOI: 10.1186/s12931-020-01591-x  0.379
2020 Prince A, Wong Fok Lung T. Consequences of Metabolic Interactions during Infection. Toxins. 12. PMID 32917040 DOI: 10.3390/Toxins12090581  0.405
2020 Ahn D, Prince A. Participation of the IL-10RB Related Cytokines, IL-22 and IFN-λ in Defense of the Airway Mucosal Barrier. Frontiers in Cellular and Infection Microbiology. 10: 300. PMID 32637365 DOI: 10.3389/fcimb.2020.00300  0.33
2020 Riquelme SA, Liimatta K, Wong Fok Lung T, Fields B, Ahn D, Chen D, Lozano C, Sáenz Y, Uhlemann AC, Kahl BC, Britto CJ, DiMango E, Prince A. Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation. Cell Metabolism. PMID 32428444 DOI: 10.1016/J.Cmet.2020.04.017  0.451
2020 Riquelme SA, Wong Fok Lung T, Prince A. Pulmonary Pathogens Adapt to Immune Signaling Metabolites in the Airway. Frontiers in Immunology. 11: 385. PMID 32231665 DOI: 10.3389/fimmu.2020.00385  0.357
2019 Wong Fok Lung T, Monk IR, Acker KP, Mu A, Wang N, Riquelme SA, Pires S, Noguera LP, Dach F, Gabryszewski SJ, Howden BP, Prince A. Staphylococcus aureus small colony variants impair host immunity by activating host cell glycolysis and inducing necroptosis. Nature Microbiology. PMID 31686028 DOI: 10.1038/S41564-019-0597-0  0.474
2019 Acker KP, Wong Fok Lung T, West E, Craft J, Narechania A, Smith H, O'Brien K, Moustafa AM, Lauren C, Planet PJ, Prince A. Strains of Staphylococcus aureus that Colonize and Infect Skin Harbor Mutations in Metabolic Genes. Iscience. 19: 281-290. PMID 31401351 DOI: 10.1016/J.Isci.2019.07.037  0.693
2019 Riquelme SA, Lozano C, Moustafa AM, Liimatta K, Tomlinson KL, Britto C, Khanal S, Gill SK, Narechania A, Azcona-Gutiérrez JM, DiMango E, Saénz Y, Planet P, Prince A. CFTR-PTEN-dependent mitochondrial metabolic dysfunction promotes airway infection. Science Translational Medicine. 11. PMID 31270271 DOI: 10.1126/Scitranslmed.Aav4634  0.706
2019 Gabryszewski SJ, Wong Fok Lung T, Annavajhala MK, Tomlinson KL, Riquelme SA, Khan IN, Noguera LP, Wickersham M, Zhao A, Mulenos AM, Peaper D, Koff JL, Uhlemann AC, Prince A. Metabolic Adaptation Supports Persistent Methicillin-Resistant Staphylococcus aureus Pulmonary Infection. American Journal of Respiratory Cell and Molecular Biology. PMID 30742488 DOI: 10.1165/Rcmb.2018-0389Oc  0.403
2018 Ahn D, Wickersham M, Riquelme S, Prince A. The Effects of IFN-λ on Epithelial Barrier Function Contribute to K. pneumoniae ST258 Pneumonia. American Journal of Respiratory Cell and Molecular Biology. PMID 30183325 DOI: 10.1165/Rcmb.2018-0021Oc  0.434
2018 Riquelme SA, Ahn D, Prince A. Pseudomonas aeruginosa and Klebsiella pneumoniae Adaptation to Innate Immune Clearance Mechanisms in the Lung. Journal of Innate Immunity. PMID 29617698 DOI: 10.1159/000487515  0.459
2018 Acker K, Wong T, West ES, Planet P, Prince A. 625. Metabolic Interactions Drive Staphylococcus aureus Adaptation to the Skin Open Forum Infectious Diseases. 5: S228-S228. DOI: 10.1093/Ofid/Ofy210.632  0.356
2017 Riquelme SA, Hopkins BD, Wolfe AL, DiMango E, Kitur K, Parsons R, Prince A. Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity. Immunity. 47: 1169-1181.e7. PMID 29246444 DOI: 10.1016/J.Immuni.2017.11.010  0.44
2017 Ahn D, Prince A. Participation of Necroptosis in the Host Response to Acute Bacterial Pneumonia. Journal of Innate Immunity. PMID 28125817 DOI: 10.1159/000455100  0.399
2016 Ahn D, Peñaloza H, Wang Z, Wickersham M, Parker D, Patel P, Koller A, Chen EI, Bueno SM, Uhlemann AC, Prince A. Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection. Jci Insight. 1: e89704. PMID 27777978 DOI: 10.1172/jci.insight.89704  0.348
2016 Parker D, Prince A. Immunoregulatory effects of necroptosis in bacterial infections. Cytokine. 88: 274-275. PMID 27710879 DOI: 10.1016/J.Cyto.2016.09.024  0.398
2016 Prince A, Wang H, Kitur K, Parker D. Humanized mice exhibit increased susceptibility to Staphylococcus aureus pneumonia. The Journal of Infectious Diseases. PMID 27638942 DOI: 10.1093/Infdis/Jiw425  0.433
2016 Kitur K, Wachtel S, Brown A, Wickersham M, Paulino F, Peñaloza HF, Soong G, Bueno S, Parker D, Prince A. Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling. Cell Reports. PMID 27524612 DOI: 10.1016/J.Celrep.2016.07.039  0.441
2016 Parker D, Prince A. A new approach to toxin neutralization in Staphylococcus aureus therapy. Embo Reports. 17: 284-5. PMID 26882555 DOI: 10.15252/Embr.201642015  0.404
2016 Planet PJ, Parker D, Cohen TS, Smith H, Leon JD, Ryan C, Hammer TJ, Fierer N, Chen EI, Prince AS. Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection. Mbio. 7. PMID 26861017 DOI: 10.1128/Mbio.01939-15  0.316
2016 Parker D, Ahn D, Cohen T, Prince A. Innate Immune Signaling Activated by MDR Bacteria in the Airway. Physiological Reviews. 96: 19-53. PMID 26582515 DOI: 10.1152/Physrev.00009.2015  0.429
2015 Soong G, Paulino F, Wachtel S, Parker D, Wickersham M, Zhang D, Brown A, Lauren C, Dowd M, West E, Horst B, Planet P, Prince A. Methicillin-resistant Staphylococcus aureus adaptation to human keratinocytes. Mbio. 6. PMID 25900653 DOI: 10.1128/Mbio.00289-15  0.465
2015 Kitur K, Parker D, Nieto P, Ahn DS, Cohen TS, Chung S, Wachtel S, Bueno S, Prince A. Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage. Plos Pathogens. 11: e1004820. PMID 25880560 DOI: 10.1371/Journal.Ppat.1004820  0.49
2015 Parker D, Ryan CL, Alonzo F, Torres VJ, Planet PJ, Prince AS. CD4+ T cells promote the pathogenesis of Staphylococcus aureus pneumonia. The Journal of Infectious Diseases. 211: 835-45. PMID 25240171 DOI: 10.1093/Infdis/Jiu525  0.334
2015 Parker D, Planet P, Cohen T, Smith H, Leon J, Ryan C, Hammer T, Fierer N, Cheng E, Prince A. ID: 248 Cytokine. 76: 111. DOI: 10.1016/J.Cyto.2015.08.251  0.44
2014 Ahn DS, Parker D, Planet PJ, Nieto PA, Bueno SM, Prince A. Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia. Mucosal Immunology. 7: 1366-74. PMID 24736233 DOI: 10.1038/Mi.2014.24  0.46
2014 Parker D, Planet PJ, Soong G, Narechania A, Prince A. Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains. Plos Pathogens. 10: e1003951. PMID 24586160 DOI: 10.1371/Journal.Ppat.1003951  0.375
2014 Westphalen K, Gusarova GA, Islam MN, Subramanian M, Cohen TS, Prince AS, Bhattacharya J. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Nature. 506: 503-6. PMID 24463523 DOI: 10.1038/nature12902  0.377
2014 Paulino F, Planet P, Soong G, Parker D, Zhang D, West E, Prince A. 74In vivo Selection of S. aureus agr Mutants in Human Keratinocytes Open Forum Infectious Diseases. 1: S1-S1. DOI: 10.1093/Ofid/Ofu051.04  0.304
2013 Planet PJ, LaRussa SJ, Dana A, Smith H, Xu A, Ryan C, Uhlemann AC, Boundy S, Goldberg J, Narechania A, Kulkarni R, Ratner AJ, Geoghegan JA, Kolokotronis SO, Prince A. Emergence of the epidemic methicillin-resistant Staphylococcus aureus strain USA300 coincides with horizontal transfer of the arginine catabolic mobile element and speG-mediated adaptations for survival on skin. Mbio. 4: e00889-13. PMID 24345744 DOI: 10.1128/Mbio.00889-13  0.385
2013 Cohen TS, Prince AS. Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4. Plos Pathogens. 9: e1003682. PMID 24098127 DOI: 10.1371/Journal.Ppat.1003682  0.349
2013 Parker D, Prince A. Epithelial uptake of flagella initiates proinflammatory signaling. Plos One. 8: e59932. PMID 23527288 DOI: 10.1371/journal.pone.0059932  0.398
2013 Cohen TS, Prince AS. Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia. The Journal of Clinical Investigation. 123: 1630-7. PMID 23478406 DOI: 10.1172/Jci66142  0.415
2013 Parker D, Soong G, Planet P, Prince A. 195 Cytokine. 63: 289. DOI: 10.1016/J.Cyto.2013.06.198  0.383
2013 Cohen TS, Prince A. 52: Programmed cell death 4 (PDCD4) regulates proinflammatory cytokine signaling in bacterial pneumonia Cytokine. 63: 255. DOI: 10.1016/J.Cyto.2013.06.055  0.397
2012 Recinos DA, Sekedat MD, Hernandez A, Cohen TS, Sakhtah H, Prince AS, Price-Whelan A, Dietrich LE. Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity. Proceedings of the National Academy of Sciences of the United States of America. 109: 19420-5. PMID 23129634 DOI: 10.1073/Pnas.1213901109  0.316
2012 Prince A. The bitter taste of infection. The Journal of Clinical Investigation. 122: 3847-9. PMID 23041625 DOI: 10.1172/Jci66182  0.459
2012 Parker D, Prince A. Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9. Journal of Immunology (Baltimore, Md. : 1950). 189: 4040-6. PMID 22962685 DOI: 10.4049/Jimmunol.1201055  0.502
2012 Garofalo A, Giai C, Lattar S, Gardella N, Mollerach M, Kahl BC, Becker K, Prince AS, Sordelli DO, Gómez MI. The length of the Staphylococcus aureus protein A polymorphic region regulates inflammation: impact on acute and chronic infection. The Journal of Infectious Diseases. 206: 81-90. PMID 22535996 DOI: 10.1093/infdis/jis311  0.369
2012 Cohen TS, Prince A. Cystic fibrosis: a mucosal immunodeficiency syndrome. Nature Medicine. 18: 509-19. PMID 22481418 DOI: 10.1038/Nm.2715  0.443
2012 Soong G, Chun J, Parker D, Prince A. Staphylococcus aureus activation of caspase 1/calpain signaling mediates invasion through human keratinocytes. The Journal of Infectious Diseases. 205: 1571-9. PMID 22457275 DOI: 10.1093/Infdis/Jis244  0.781
2012 Parker D, Prince A. Immunopathogenesis of Staphylococcus aureus pulmonary infection. Seminars in Immunopathology. 34: 281-97. PMID 22037948 DOI: 10.1007/S00281-011-0291-7  0.486
2012 Parker D, Cohen TS, Alhede M, Harfenist BS, Martin FJ, Prince A. Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 46: 6-13. PMID 21778412 DOI: 10.1165/Rcmb.2011-0080Oc  0.667
2012 Cohen TS, Prince A. P137 Type III interferon impairs bacterial clearance through PDCD4 regulated inflammatory cytokine production Cytokine. 59: 563. DOI: 10.1016/J.Cyto.2012.06.229  0.516
2011 Parker D, Prince A. Type I interferon response to extracellular bacteria in the airway epithelium. Trends in Immunology. 32: 582-8. PMID 21996313 DOI: 10.1016/J.It.2011.09.003  0.479
2011 Soong G, Martin FJ, Chun J, Cohen TS, Ahn DS, Prince A. Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity. The Journal of Biological Chemistry. 286: 35891-8. PMID 21878647 DOI: 10.1074/Jbc.M111.295386  0.774
2011 Parker D, Martin FJ, Soong G, Harfenist BS, Aguilar JL, Ratner AJ, Fitzgerald KA, Schindler C, Prince A. Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract. Mbio. 2: e00016-11. PMID 21586648 DOI: 10.1128/Mbio.00016-11  0.626
2011 Martin FJ, Parker D, Harfenist BS, Soong G, Prince A. Participation of CD11c(+) leukocytes in methicillin-resistant Staphylococcus aureus clearance from the lung. Infection and Immunity. 79: 1898-904. PMID 21402768 DOI: 10.1128/Iai.01299-10  0.647
2011 Parker D, Prince A. Innate immunity in the respiratory epithelium. American Journal of Respiratory Cell and Molecular Biology. 45: 189-201. PMID 21330463 DOI: 10.1165/Rcmb.2011-0011Rt  0.438
2010 Lee MH, Arrecubieta C, Martin FJ, Prince A, Borczuk AC, Lowy FD. A postinfluenza model of Staphylococcus aureus pneumonia. The Journal of Infectious Diseases. 201: 508-15. PMID 20078212 DOI: 10.1086/650204  0.596
2009 Chun J, Prince A. Ca2+ signaling in airway epithelial cells facilitates leukocyte recruitment and transepithelial migration. Journal of Leukocyte Biology. 86: 1135-44. PMID 19605699 DOI: 10.1189/Jlb.0209072  0.778
2009 Martin FJ, Gomez MI, Wetzel DM, Memmi G, O'Seaghdha M, Soong G, Schindler C, Prince A. Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A. The Journal of Clinical Investigation. 119: 1931-9. PMID 19603548 DOI: 10.1172/Jci35879  0.64
2009 Parker D, Soong G, Planet P, Brower J, Ratner AJ, Prince A. The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation. Infection and Immunity. 77: 3722-30. PMID 19564377 DOI: 10.1128/Iai.00228-09  0.42
2009 Hsiao YS, Parker D, Ratner AJ, Prince A, Tong L. Crystal structures of respiratory pathogen neuraminidases. Biochemical and Biophysical Research Communications. 380: 467-71. PMID 19284989 DOI: 10.1016/J.Bbrc.2009.01.108  0.368
2009 Chun J, Prince A. TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration. Cell Host & Microbe. 5: 47-58. PMID 19154987 DOI: 10.1016/J.Chom.2008.11.009  0.796
2008 Martin FJ, Prince AS. TLR2 regulates gap junction intercellular communication in airway cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 4986-93. PMID 18354224 DOI: 10.4049/Jimmunol.180.7.4986  0.617
2008 Soong G, Parker D, Magargee M, Prince AS. The type III toxins of Pseudomonas aeruginosa disrupt epithelial barrier function. Journal of Bacteriology. 190: 2814-21. PMID 18165298 DOI: 10.1128/JB.01567-07  0.356
2008 Gómez MI, Prince A. Airway epithelial cell signaling in response to bacterial pathogens. Pediatric Pulmonology. 43: 11-9. PMID 18041080 DOI: 10.1002/Ppul.20735  0.485
2007 Gómez MI, Prince A. Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Current Opinion in Pharmacology. 7: 244-51. PMID 17418640 DOI: 10.1016/J.Coph.2006.12.005  0.482
2007 Gómez MI, Seaghdha MO, Prince AS. Staphylococcus aureus protein A activates TACE through EGFR-dependent signaling. The Embo Journal. 26: 701-9. PMID 17255933 DOI: 10.1038/sj.emboj.7601554  0.315
2007 Waters VJ, Gómez MI, Soong G, Amin S, Ernst RK, Prince A. Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia. Infection and Immunity. 75: 1698-703. PMID 17220304 DOI: 10.1128/Iai.01469-06  0.458
2006 Soong G, Muir A, Gomez MI, Waks J, Reddy B, Planet P, Singh PK, Kaneko Y, Kanetko Y, Wolfgang MC, Hsiao YS, Tong L, Prince A. Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production. The Journal of Clinical Investigation. 116: 2297-2305. PMID 16862214 DOI: 10.1172/Jci27920  0.447
2006 Chun J, Prince A. Activation of Ca2+-dependent signaling by TLR2. Journal of Immunology (Baltimore, Md. : 1950). 177: 1330-7. PMID 16818794 DOI: 10.4049/Jimmunol.177.2.1330  0.78
2006 Prince AS, Mizgerd JP, Wiener-Kronish J, Bhattacharya J. Cell signaling underlying the pathophysiology of pneumonia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L297-300. PMID 16648241 DOI: 10.1152/Ajplung.00138.2006  0.382
2006 Soong G, Muir A, Gomez MI, Waks J, Reddy B, Planet P, Singh PK, Kanetko Y, Wolfgang MC, Hsiao Y, Tong L, Prince A. Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production Journal of Clinical Investigation. 116: 2828-2828. DOI: 10.1172/Jci27920C1  0.385
2005 Wagner T, Soong G, Sokol S, Saiman L, Prince A. Effects of azithromycin on clinical isolates of Pseudomonas aeruginosa from cystic fibrosis patients. Chest. 128: 912-9. PMID 16100186 DOI: 10.1378/Chest.128.2.912  0.41
2005 Gómez MI, Sokol SH, Muir AB, Soong G, Bastien J, Prince AS. Bacterial induction of TNF-alpha converting enzyme expression and IL-6 receptor alpha shedding regulates airway inflammatory signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 1930-6. PMID 16034137 DOI: 10.4049/Jimmunol.175.3.1930  0.329
2005 Waters V, Sokol S, Reddy B, Soong G, Chun J, Prince A. The effect of cyclosporin A on airway cell proinflammatory signaling and pneumonia. American Journal of Respiratory Cell and Molecular Biology. 33: 138-44. PMID 15879161 DOI: 10.1165/Rcmb.2005-0005Oc  0.802
2005 Sadikot RT, Blackwell TS, Christman JW, Prince AS. Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. American Journal of Respiratory and Critical Care Medicine. 171: 1209-23. PMID 15695491 DOI: 10.1164/Rccm.200408-1044So  0.348
2004 Gómez MI, Lee A, Reddy B, Muir A, Soong G, Pitt A, Cheung A, Prince A. Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nature Medicine. 10: 842-8. PMID 15247912 DOI: 10.1038/Nm1079  0.342
2004 Soong G, Reddy B, Sokol S, Adamo R, Prince A. TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. The Journal of Clinical Investigation. 113: 1482-9. PMID 15146246 DOI: 10.1172/JCI20773  0.383
2004 Muir A, Soong G, Sokol S, Reddy B, Gomez MI, Van Heeckeren A, Prince A. Toll-like receptors in normal and cystic fibrosis airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 30: 777-83. PMID 14656745 DOI: 10.1165/rcmb.2003-0329OC  0.37
2004 Adamo R, Sokol S, Soong G, Gomez MI, Prince A. Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5. American Journal of Respiratory Cell and Molecular Biology. 30: 627-34. PMID 14607814 DOI: 10.1165/Rcmb.2003-0260Oc  0.482
2002 Saba S, Soong G, Greenberg S, Prince A. Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways. American Journal of Respiratory Cell and Molecular Biology. 27: 561-7. PMID 12397015 DOI: 10.1165/Rcmb.2002-0019Oc  0.49
2002 Bryan R, Prince A. Bacterial-epithelial interactions. Methods in Molecular Medicine. 70: 465-78. PMID 11917543 DOI: 10.1385/1-59259-187-6:465  0.311
2002 Heyer G, Saba S, Adamo R, Rush W, Soong G, Cheung A, Prince A. Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung. Infection and Immunity. 70: 127-33. PMID 11748173 DOI: 10.1128/Iai.70.1.127-133.2002  0.51
2001 Rastogi D, Ratner AJ, Prince A. Host-bacterial interactions in the initiation of inflammation. Paediatric Respiratory Reviews. 2: 245-52. PMID 12052326 DOI: 10.1053/prrv.2001.0147  0.428
2001 Weber AJ, Soong G, Bryan R, Saba S, Prince A. Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L71-8. PMID 11404248 DOI: 10.1152/Ajplung.2001.281.1.L71  0.404
2001 Ratner AJ, Bryan R, Weber A, Nguyen S, Barnes D, Pitt A, Gelber S, Cheung A, Prince A. Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells. The Journal of Biological Chemistry. 276: 19267-75. PMID 11278360 DOI: 10.1074/Jbc.M007703200  0.482
2000 Rajan S, Cacalano G, Bryan R, Ratner AJ, Sontich CU, van Heerckeren A, Davis P, Prince A. Pseudomonas aeruginosa induction of apoptosis in respiratory epithelial cells: analysis of the effects of cystic fibrosis transmembrane conductance regulator dysfunction and bacterial virulence factors. American Journal of Respiratory Cell and Molecular Biology. 23: 304-12. PMID 10970820 DOI: 10.1165/Ajrcmb.23.3.4098  0.479
2000 Pearson JP, Feldman M, Iglewski BH, Prince A. Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection Infection and Immunity. 68: 4331-4334. PMID 10858254 DOI: 10.1128/Iai.68.7.4331-4334.2000  0.432
1999 Worgall S, Bezdicek P, Kim MK, Park JG, Singh R, Christofidou-Solomidou M, Prince A, Kovesdi I, Schreiber AD, Crystal RG. Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium. The Journal of Clinical Investigation. 104: 409-18. PMID 10449433 DOI: 10.1172/Jci5432  0.395
1999 Bryan R, Feldman M, Jawetz SC, Rajan S, DiMango E, Tang HB, Scheffler L, Speert DP, Prince A. The effects of aerosolized dextran in a mouse model of Pseudomonas aeruginosa pulmonary infection Journal of Infectious Diseases. 179: 1449-1458. PMID 10228067 DOI: 10.1086/314755  0.478
1999 Rajan S, Bryan R, Prince A. Induction of Apoptosis in Airway Epithelial Cells by P.aeruginosa Pediatric Research. 45. DOI: 10.1203/00006450-199904020-01019  0.369
1998 Bryan R, Kube D, Perez A, Davis P, Prince A. Overproduction of the CFTR R domain leads to increased levels of asialoGM1 and increased Pseudomonas aeruginosa binding by epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 19: 269-77. PMID 9698599 DOI: 10.1165/Ajrcmb.19.2.2889  0.401
1998 DiMango E, Ratner AJ, Bryan R, Tabibi S, Prince A. Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. The Journal of Clinical Investigation. 101: 2598-605. PMID 9616231 DOI: 10.1172/Jci2865  0.462
1998 Rajan S, Bryan R, Ratner AJ, Prince A. Pseudomonas aeruginosa Interactions with Epithelial Cells: Adherence, Invasion and Apoptosis ♦ 896 Pediatric Research. 43: 155-155. DOI: 10.1203/00006450-199804001-00917  0.428
1998 Heyer G, Bryan R, Cheung A, Prince A. Staphylococcus aureus virulence in the respiratory tract:agr and sar dependent activation of epithelial Ca2+ fluxes and IL-8 expression ♦ 849 Pediatric Research. 43: 147-147. DOI: 10.1203/00006450-199804001-00870  0.516
1998 Feldman M, Bryan R, Rajan S, Scheffler L, Brunnert S, Tang H, Prince A. Role of Flagella in Pathogenesis ofPseudomonas aeruginosa Pulmonary Infection Infection and Immunity. 66: 43-51. DOI: 10.1128/Iai.66.1.43-51.1998  0.481
1997 Li JD, Dohrman AF, Gallup M, Miyata S, Gum JR, Kim YS, Nadel JA, Prince A, Basbaum CB. Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proceedings of the National Academy of Sciences of the United States of America. 94: 967-72. PMID 9023366 DOI: 10.1073/Pnas.94.3.967  0.424
1996 Saiman L, Mehar F, Niu WW, Neu HC, Shaw KJ, Miller G, Prince A. Antibiotic Susceptibility of Multiply Resistant Pseudomonas aeruginosa Isolated from Patients with Cystic Fibrosis, Including Candidates for Transplantation Clinical Infectious Diseases. 23: 532-537. PMID 8879776 DOI: 10.1093/Clinids/23.3.532  0.343
1996 Tang HB, Dimango E, Bryan R, Gambello M, Iglewski BH, Goldberg JB, Prince A. Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection Infection and Immunity. 64: 37-43. PMID 8557368 DOI: 10.1128/Iai.64.1.37-43.1996  0.47
1996 Bryan R, Feldman M, Speert D, Prince A. THE USE OF CARBOHYDRATES TO BLOCK THE ATTACHMENT OF PSEUDOMONAS AERUGINOSA TO EPITHELIAL CELLS. • 2290 Pediatric Research. 39: 384-384. DOI: 10.1203/00006450-199604001-02315  0.362
1995 Imundo L, Barasch J, Prince A, Al-Awqati Q. Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface Proceedings of the National Academy of Sciences of the United States of America. 92: 3019-3023. PMID 7708767 DOI: 10.1073/Pnas.92.7.3019  0.428
1995 DiMango E, Zar HJ, Bryan R, Prince A. Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8. The Journal of Clinical Investigation. 96: 2204-10. PMID 7593606 DOI: 10.1172/Jci118275  0.431
1995 Zar H, Saiman L, Quittell L, Prince A. Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patients with various mutations in the cystic fibrosis transmembrane regulator. The Journal of Pediatrics. 126: 230-3. PMID 7531240 DOI: 10.1016/S0022-3476(95)70549-X  0.373
1992 Cacalano G, Kays M, Saiman L, Prince A. Production of the Pseudomonas aeruginosa neuraminidase is increased under hyperosmolar conditions and is regulated by genes involved in alginate expression. The Journal of Clinical Investigation. 89: 1866-74. PMID 1601994 DOI: 10.1172/Jci115791  0.477
1992 Prince A. Adhesins and receptors of Pseudomonas aeruginosa associated with infection of the respiratory tract. Microbial Pathogenesis. 13: 251-260. PMID 1363702 DOI: 10.1016/0882-4010(92)90035-M  0.477
1992 Saiman L, Cacalano G, Gruenert D, Prince A. Comparison of adherence of Pseudomonas aeruginosa to respiratory epithelial cells from cystic fibrosis patients and healthy subjects. Infection and Immunity. 60: 2808-2814. DOI: 10.1128/Iai.60.7.2808-2814.1992  0.39
1991 Barasch J, Kiss B, Prince A, Saiman L, Gruenert D, al-Awqati Q. Defective acidification of intracellular organelles in cystic fibrosis. Nature. 352: 70-3. PMID 1712081 DOI: 10.1038/352070A0  0.323
1990 Saiman L, Ishimoto K, Lory S, Prince A. The effect of piliation and exoproduct expression on the adherence of Pseudomonas aeruginosa to respiratory epithelial monolayers Journal of Infectious Diseases. 161: 541-548. PMID 1968936 DOI: 10.1093/Infdis/161.3.541  0.338
1990 Saiman L, Cacalano G, Prince A. Pseudomonas cepacia adherence to respiratory epithelial cells is enhanced by Pseudomonas aeruginosa. Infection and Immunity. 58: 2578-2584. DOI: 10.1128/Iai.58.8.2578-2584.1990  0.353
1988 Prince A, Wood MS, Cacalano GS, Chin NX. Isolation and characterization of a penicillinase from Pseudomonas cepacia 249. Antimicrobial Agents and Chemotherapy. 32: 838-43. PMID 3046483 DOI: 10.1128/Aac.32.6.838  0.303
1986 Prince A. Antibiotic resistance of Pseudomonas species. The Journal of Pediatrics. 108: 830-4. PMID 3701534 DOI: 10.1016/S0022-3476(86)80753-3  0.311
Low-probability matches (unlikely to be authored by this person)
2017 Shah S, Fidock D, Prince A. Hemozoin Directly Induces Inflammation and Upregulation of CD36 in Lung Epithelium and Endothelium Open Forum Infectious Diseases. 4: S224-S224. DOI: 10.1093/Ofid/Ofx163.464  0.299
2017 Ahn D, Prince A. Host-Pathogen Interface: Progress in Understanding the Pathogenesis of Infection Due to Multidrug-Resistant Bacteria in the Intensive Care Unit. The Journal of Infectious Diseases. 215: S1-S8. PMID 28375516 DOI: 10.1093/infdis/jiw405  0.295
2017 Wickersham M, Wachtel S, Wong Fok Lung T, Soong G, Jacquet R, Richardson A, Parker D, Prince A. Metabolic Stress Drives Keratinocyte Defenses against Staphylococcus aureus Infection. Cell Reports. 18: 2742-2751. PMID 28297676 DOI: 10.1016/j.celrep.2017.02.055  0.295
1996 Tang HB, DiMango E, Bryan R, Gambello M, Iglewski BH, Goldberg JB, Prince A. Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection. Infection and Immunity. 64: 37-43. DOI: 10.1128/iai.64.1.37-43.1996  0.294
2018 Hook JL, Islam MN, Parker D, Prince AS, Bhattacharya S, Bhattacharya J. Disruption of staphylococcal aggregation protects against lethal lung injury. The Journal of Clinical Investigation. PMID 29431734 DOI: 10.1172/JCI95823  0.292
2023 Prince A, Wong Fok Lung T. Immunometabolic control by . Immunometabolism (Cobham, Surrey). 5: e00028. PMID 37492184 DOI: 10.1097/IN9.0000000000000028  0.291
2017 Wolfe AL, Hopkins BD, Riquelme SA, Kitur K, Ozturk S, Kang K, Remark R, Rahman A, Lin C, Merad M, Szabolcs M, Chen S, Prince A, Parsons R. Abstract 334: PTEN-L regulates epithelial growth and macrophage function Cancer Research. 77: 334-334. DOI: 10.1158/1538-7445.Am2017-334  0.291
2002 Prince AS. Biofilms, antimicrobial resistance, and airway infection. The New England Journal of Medicine. 347: 1110-1. PMID 12362015 DOI: 10.1056/NEJMcibr021776  0.289
1998 Prince A. The CFTR advantage--capitalizing on a quirk of fate. Nature Medicine. 4: 663-4. PMID 9623968 DOI: 10.1038/Nm0698-663  0.285
2014 Parker D, Narechania A, Sebra R, Deikus G, Larussa S, Ryan C, Smith H, Prince A, Mathema B, Ratner AJ, Kreiswirth B, Planet PJ. Genome Sequence of Bacterial Interference Strain Staphylococcus aureus 502A. Genome Announcements. 2. PMID 24723721 DOI: 10.1128/Genomea.00284-14  0.281
2019 Peñaloza HF, Noguera LP, Ahn D, Vallejos OP, Castellanos RM, Vazquez Y, Salazar-Echegarai FJ, González L, Suazo I, Pardo-Roa C, Salazar GA, Prince A, Bueno SM. Interleukin-10 produced by myeloid derived suppressor cells provides protection to Carbapenem-resistant ST258 by enhancing its clearance in the airways. Infection and Immunity. PMID 30804104 DOI: 10.1128/IAI.00665-18  0.274
2006 Adler KB, Shapiro SD, Gallup M, Wu R, Randell SH, Holtzman MJ, Evans CM, Jacoby DB, Tesfaigzi Y, Rose MC, Mossman BT, Prince A, Reddy SP, Davis CW, Matthay MA. Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. American Journal of Respiratory Cell and Molecular Biology. 34: 523-6. PMID 16618787 DOI: 10.1165/Rcmb.F311  0.272
2018 Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, ... ... Prince AS, et al. Future Research Directions in Pneumonia: NHLBI Working Group Report. American Journal of Respiratory and Critical Care Medicine. PMID 29546996 DOI: 10.1164/Rccm.201801-0139Ws  0.27
2012 Ahn D, Parker D, Planet P, Prince A. 173 Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424393.89408.28  0.265
1993 Proenca R, Niu WW, Cacalano G, Prince A. The Pseudomonas cepacia 249 chromosomal penicillinase is a member of the AmpC family of chromosomal beta-lactamases. Antimicrobial Agents and Chemotherapy. 37: 667-674. PMID 8494361 DOI: 10.1128/Aac.37.4.667  0.26
1995 Tang H, Kays M, Prince A. Role of Pseudomonas aeruginosa pili in acute pulmonary infection. Infection and Immunity. 63: 1278-1285. DOI: 10.1128/iai.63.4.1278-1285.1995  0.257
1976 Prince A, Neu HC. Beta-lactamase activity in Shigella sonnei. Antimicrobial Agents and Chemotherapy. 9: 776-779. PMID 782355 DOI: 10.1128/Aac.9.5.776  0.256
2006 Prince A. Flagellar activation of epithelial signaling. American Journal of Respiratory Cell and Molecular Biology. 34: 548-51. PMID 16439803 DOI: 10.1165/rcmb.2006-0022SF  0.248
2006 Gómez MI, O'Seaghdha M, Magargee M, Foster TJ, Prince AS. Staphylococcus aureus protein A activates TNFR1 signaling through conserved IgG binding domains. The Journal of Biological Chemistry. 281: 20190-6. PMID 16709567 DOI: 10.1074/jbc.M601956200  0.246
2021 O'Toole GA, Crabbé A, Kümmerli R, LiPuma JJ, Bomberger JM, Davies JC, Limoli D, Phelan VV, Bliska JB, DePas WH, Dietrich LE, Hampton TH, Hunter R, Khursigara CM, Price-Whelan A, ... ... Prince A, et al. Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions. Mbio. e0176321. PMID 34544277 DOI: 10.1128/mBio.01763-21  0.244
2000 Ratner AJ, Prince A. Lactoperoxidase. New recognition of an "old" enzyme in airway defenses. American Journal of Respiratory Cell and Molecular Biology. 22: 642-4. PMID 10837358 DOI: 10.1165/Ajrcmb.22.6.F186  0.236
1995 Rosh JR, Tang HB, Mayer L, Groisman G, Abraham SK, Prince A. Treatment of intractable gastrointestinal manifestations of chronic granulomatous disease with cyclosporine. The Journal of Pediatrics. 126: 143-5. PMID 7815206 DOI: 10.1016/S0022-3476(95)70519-8  0.23
2006 Rothbaum E, Nicholson O, Prince A. Cerebral abscess associated with meningococcal meningitis. The Pediatric Infectious Disease Journal. 25: 754-6. PMID 16874183 DOI: 10.1097/01.Inf.0000227808.81951.74  0.223
2022 Rosenberg G, Riquelme S, Prince A, Avraham R. Immunometabolic crosstalk during bacterial infection. Nature Microbiology. 7: 497-507. PMID 35365784 DOI: 10.1038/s41564-022-01080-5  0.218
2011 Pier G, Prince A, Cantin A. Cystic fibrosis: an-ion transport issue? Nature Medicine. 17: 166-7. PMID 21297610 DOI: 10.1038/Nm0211-166  0.215
2013 Prince A. Mucosal immunology of acute bacterial pneumonia Mucosal Immunology of Acute Bacterial Pneumonia. 1-277. DOI: 10.1007/978-1-4614-5326-0  0.209
2015 Amaral FE, Parker D, Randis TM, Kulkarni R, Prince AS, Shirasu-Hiza MM, Ratner AJ. Rational manipulation of mRNA folding free energy allows rheostat control of pneumolysin production by Streptococcus pneumoniae. Plos One. 10: e0119823. PMID 25798590 DOI: 10.1371/journal.pone.0119823  0.208
2003 Prince AS. The host response to anthrax lethal toxin: unexpected observations. The Journal of Clinical Investigation. 112: 656-8. PMID 12952914 DOI: 10.1172/JCI19581  0.2
1993 Saiman L, Prince A, Gersony WM. Pediatric infective endocarditis in the modern era. The Journal of Pediatrics. 122: 847-53. PMID 8501558 DOI: 10.1016/S0022-3476(09)90006-3  0.175
1986 Prince A, Heller B, Levy J, Heird WC. Management of fever in patients with central vein catheters. Pediatric Infectious Disease. 5: 20-4. PMID 3080737 DOI: 10.1097/00006454-198601000-00004  0.169
2022 Wong Fok Lung T, Chan LC, Prince A, Yeaman MR, Archer NK, Aman MJ, Proctor RA. adaptive evolution: Recent insights on how immune evasion, immunometabolic subversion and host genetics impact vaccine development. Frontiers in Cellular and Infection Microbiology. 12: 1060810. PMID 36636720 DOI: 10.3389/fcimb.2022.1060810  0.154
2017 Prince A. Participation of Host Determinants in the Pathogenesis of Pneumonia. Journal of Innate Immunity. PMID 28259885 DOI: 10.1159/000460276  0.149
1989 Saiman L, Sadoff J, Prince A. Cross-reactivity of Pseudomonas aeruginosa antipilin monoclonal antibodies with heterogeneous strains of P. aeruginosa and Pseudomonas cepacia. Infection and Immunity. 57: 2764-2770. DOI: 10.1128/iai.57.9.2764-2770.1989  0.121
1986 Bakshi SS, Miller TC, Kaplan M, Hammerschlag MR, Prince A, Gershon AA. Failure of varicella-zoster immunoglobulin in modification of severe congenital varicella Pediatric Infectious Disease. 5: 699-702. PMID 3025821 DOI: 10.1097/00006454-198611000-00020  0.116
2020 Prince A. Staphylcoccus aureus metabolites promote IL-10. Nature Microbiology. 5: 1183-1184. PMID 32963374 DOI: 10.1038/s41564-020-00791-x  0.095
1977 Neu HC, Prince A, Neu CO, Garvey GJ. Incidence of diarrhea and colitis associated with clindamycin therapy. The Journal of Infectious Diseases. S120-5. PMID 850085 DOI: 10.1093/infdis/135.Supplement.S120  0.088
2003 Prince AS. New insights from an old model. American Journal of Respiratory and Critical Care Medicine. 167: 1462-3. PMID 12770850 DOI: 10.1164/rccm.2302009  0.029
1994 Moss W, Prince A. Pericarditis complicating meningococcal meningitis in a 7-month-old boy. Clinical Pediatrics. 33: 169-71. PMID 8194295 DOI: 10.1177/000992289403300310  0.028
2018 Prince A. Omissions from a National Institute of Health (NIH) biosketch. Plos Pathogens. 14: e1006896. PMID 29746562 DOI: 10.1371/journal.ppat.1006896  0.01
1971 BROWNSELL VL, PRINCE AH. ChemInform Abstract: DIELEKTRISCHE RELAXATION EINIGER N,N-DISUBSTITUIERTER AMIDE (N,N-DIMETHYL- UND -DIPHENYL-ACETAMID) Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/chin.197102076  0.01
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