Year |
Citation |
Score |
2024 |
Deep D, Gudjonson H, Brown CC, Rose SA, Sharma R, Paucar Iza YA, Hong S, Hemmers S, Schizas M, Wang ZM, Chen Y, Wesemann DR, Pascual V, Pe'er D, Rudensky AY. Correction: Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity. The Journal of Experimental Medicine. 221. PMID 39475498 DOI: 10.1084/jem.2023119310182024c |
0.373 |
|
2024 |
Deep D, Gudjonson H, Brown CC, Rose SA, Sharma R, Paucar Iza YA, Hong S, Hemmers S, Schizas M, Wang ZM, Chen Y, Wesemann DR, Pascual V, Pe'er D, Rudensky AY. Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity. The Journal of Experimental Medicine. 221. PMID 39321257 DOI: 10.1084/jem.20231193 |
0.48 |
|
2024 |
Huang X, Rudensky AY. Regulatory T cells in the context: deciphering the dynamic interplay with the tissue environment. Current Opinion in Immunology. 89: 102453. PMID 39173413 DOI: 10.1016/j.coi.2024.102453 |
0.437 |
|
2024 |
Saavedra PHV, Trzeciak AJ, Lipshutz A, Daman AW, O'Neal AJ, Liu ZL, Wang Z, Romero-Pichardo JE, Rojas WS, Zago G, van den Brink MRM, Josefowicz SZ, Lucas CD, Anderson CJ, Rudensky AY, et al. Broad-spectrum antibiotics disrupt homeostatic efferocytosis. Nature Metabolism. PMID 39122784 DOI: 10.1038/s42255-024-01107-7 |
0.713 |
|
2024 |
Mendoza A, Bou-Puerto R, Giovanelli P, Dikiy S, Andretta E, Rudensky A. Regulatory T cells restrain skin inflammation by modulating peripheral neuron activation. Biorxiv : the Preprint Server For Biology. PMID 38798541 DOI: 10.1101/2024.05.14.594055 |
0.377 |
|
2024 |
Luan J, Truong C, Vuchkovska A, Guo W, Good J, Liu B, Gang A, Infarinato N, Stewart K, Polak L, Pasolli HA, Andretta E, Rudensky AY, Fuchs E, Miao Y. CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment. Immunity. PMID 38677291 DOI: 10.1016/j.immuni.2024.04.003 |
0.3 |
|
2023 |
Brown CC, Rudensky AY. Spatiotemporal regulation of peripheral T cell tolerance. Science (New York, N.Y.). 380: 472-478. PMID 37141369 DOI: 10.1126/science.adg6425 |
0.438 |
|
2023 |
Glasner A, Rose SA, Sharma R, Gudjonson H, Chu T, Green JA, Rampersaud S, Valdez IK, Andretta ES, Dhillon BS, Schizas M, Dikiy S, Mendoza A, Hu W, Wang ZM, ... ... Rudensky AY, et al. Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies. Nature Immunology. PMID 37127830 DOI: 10.1038/s41590-023-01504-2 |
0.461 |
|
2023 |
Dikiy S, Rudensky AY. Principles of regulatory T cell function. Immunity. 56: 240-255. PMID 36792571 DOI: 10.1016/j.immuni.2023.01.004 |
0.435 |
|
2022 |
Akagbosu B, Tayyebi Z, Shibu G, Paucar Iza YA, Deep D, Parisotto YF, Fisher L, Pasolli HA, Thevin V, Elmentaite R, Knott M, Hemmers S, Jahn L, Friedrich C, Verter J, ... ... Rudensky AY, et al. Novel antigen presenting cell imparts Treg-dependent tolerance to gut microbiota. Nature. PMID 36070798 DOI: 10.1038/s41586-022-05309-5 |
0.44 |
|
2022 |
van der Veeken J, Campbell C, Pritykin Y, Schizas M, Verter J, Hu W, Wang ZM, Matheis F, Mucida D, Charbonnier LM, Chatila TA, Rudensky AY. Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells. Immunity. PMID 35700740 DOI: 10.1016/j.immuni.2022.05.010 |
0.5 |
|
2022 |
Elias S, Sharma R, Schizas M, Valdez I, Rampersaud S, Park SM, Gonzalez-Figueroa P, Li QZ, Hoyos B, Rudensky AY. CXCR4+ Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow. The Journal of Experimental Medicine. 219. PMID 35670812 DOI: 10.1084/jem.20220047 |
0.383 |
|
2022 |
Nixon BG, Chou C, Krishna C, Dadi S, Michel AO, Cornish AE, Kansler ER, Do MH, Wang X, Capistrano KJ, Rudensky AY, Leslie CS, Li MO. Cytotoxic granzyme C-expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity. Science Immunology. 7: eabi8642. PMID 35394814 DOI: 10.1126/sciimmunol.abi8642 |
0.375 |
|
2021 |
Zhong Y, Walker SK, Pritykin Y, Leslie CS, Rudensky AY, van der Veeken J. Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families. Nature Immunology. PMID 34937932 DOI: 10.1038/s41590-021-01086-x |
0.428 |
|
2021 |
Jacobsen JT, Hu W, R Castro TB, Solem S, Galante A, Lin Z, Allon SJ, Mesin L, Bilate AM, Schiepers A, Shalek AK, Rudensky AY, Victora GD. Expression of Foxp3 by T follicular helper cells in end-stage germinal centers. Science (New York, N.Y.). 373. PMID 34437125 DOI: 10.1126/science.abe5146 |
0.475 |
|
2021 |
Hu W, Wang ZM, Feng Y, Schizas M, Hoyos BE, van der Veeken J, Verter JG, Bou-Puerto R, Rudensky AY. Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity. Nature Immunology. PMID 34426690 DOI: 10.1038/s41590-021-01001-4 |
0.496 |
|
2021 |
Wong HS, Park K, Gola A, Baptista AP, Miller CH, Deep D, Lou M, Boyd LF, Rudensky AY, Savage PA, Altan-Bonnet G, Tsang JS, Germain RN. A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells. Cell. PMID 34157301 DOI: 10.1016/j.cell.2021.05.028 |
0.449 |
|
2021 |
Mendoza A, Yewdell WT, Hoyos B, Schizas M, Bou-Puerto R, Michaels AJ, Brown CC, Chaudhuri J, Rudensky AY. Assembly of a spatial circuit of T-bet-expressing T and B lymphocytes is required for antiviral humoral immunity. Science Immunology. 6. PMID 34117110 DOI: 10.1126/sciimmunol.abi4710 |
0.426 |
|
2021 |
Campbell C, Rudensky AY. Immunotherapy breaches low-sugar dieting of tumor Treg cells. Cell Metabolism. 33: 851-852. PMID 33951469 DOI: 10.1016/j.cmet.2021.04.010 |
0.371 |
|
2021 |
Pritykin Y, van der Veeken J, Pine AR, Zhong Y, Sahin M, Mazutis L, Pe'er D, Rudensky AY, Leslie CS. A unified atlas of CD8 T cell dysfunctional states in cancer and infection. Molecular Cell. PMID 33891860 DOI: 10.1016/j.molcel.2021.03.045 |
0.447 |
|
2021 |
Dikiy S, Li J, Bai L, Jiang M, Janke L, Zong X, Hao X, Hoyos B, Wang ZM, Xu B, Fan Y, Rudensky AY, Feng Y. A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. Immunity. PMID 33838102 DOI: 10.1016/j.immuni.2021.03.020 |
0.342 |
|
2021 |
Xu K, Yin N, Peng M, Stamatiades EG, Shyu A, Li P, Zhang X, Do MH, Wang Z, Capistrano KJ, Chou C, Levine AG, Rudensky AY, Li MO. Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity. Science (New York, N.Y.). 371: 405-410. PMID 33479154 DOI: 10.1126/science.abb2683 |
0.384 |
|
2021 |
Michaels AJ, Campbell C, Bou-Puerto R, Rudensky AY. Nuclear receptor LXRβ controls fitness and functionality of activated T cells. The Journal of Experimental Medicine. 218. PMID 33373442 DOI: 10.1084/jem.20201311 |
0.497 |
|
2021 |
Hemmers S, Schizas M, Rudensky AY. T reg cell-intrinsic requirements for ST2 signaling in health and neuroinflammation. The Journal of Experimental Medicine. 218. PMID 33095261 DOI: 10.1084/jem.20201234 |
0.435 |
|
2020 |
Campbell C, Marchildon F, Michaels AJ, Takemoto N, van der Veeken J, Schizas M, Pritykin Y, Leslie CS, Intlekofer AM, Cohen P, Rudensky AY. FXR mediates T cell-intrinsic responses to reduced feeding during infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 33318189 DOI: 10.1073/pnas.2020619117 |
0.465 |
|
2020 |
van der Veeken J, Glasner A, Zhong Y, Hu W, Wang ZM, Bou-Puerto R, Charbonnier LM, Chatila TA, Leslie CS, Rudensky AY. The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries. Immunity. PMID 33176163 DOI: 10.1016/j.immuni.2020.10.010 |
0.418 |
|
2020 |
Ramsdell F, Rudensky AY. Foxp3: a genetic foundation for regulatory T cell differentiation and function. Nature Immunology. 21: 708-709. PMID 32577010 DOI: 10.1038/S41590-020-0694-5 |
0.524 |
|
2020 |
Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature. 581: 475-479. PMID 32461639 DOI: 10.1038/S41586-020-2193-0 |
0.523 |
|
2020 |
Brown C, Rudensky AY. Enforcing T cell innocence. Science (New York, N.Y.). 367: 247-248. PMID 31949067 DOI: 10.1126/Science.Aaz7741 |
0.545 |
|
2020 |
Plitas G, Rudensky AY. Regulatory T Cells in Cancer Annual Review of Cancer Biology. 4: 459-477. DOI: 10.1146/annurev-cancerbio-030419-033428 |
0.4 |
|
2019 |
Brown CC, Gudjonson H, Pritykin Y, Deep D, Lavallée VP, Mendoza A, Fromme R, Mazutis L, Ariyan C, Leslie C, Pe'er D, Rudensky AY. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 179: 846-863.e24. PMID 31668803 DOI: 10.1016/J.Cell.2019.09.035 |
0.515 |
|
2019 |
Campbell C, Rudensky A. Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism. Cell Metabolism. PMID 31607562 DOI: 10.1016/J.Cmet.2019.09.010 |
0.505 |
|
2019 |
Hemmers S, Schizas M, Azizi E, Dikiy S, Zhong Y, Feng Y, Altan-Bonnet G, Rudensky AY. IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus. The Journal of Experimental Medicine. PMID 31434685 DOI: 10.1084/Jem.20190993 |
0.527 |
|
2019 |
Elias S, Rudensky AY. Therapeutic use of regulatory T cells for graft-versus-host disease. British Journal of Haematology. PMID 31418827 DOI: 10.1111/Bjh.16157 |
0.509 |
|
2019 |
Yen WF, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen CC, Jasin M, Sun JC, Rudensky AY, et al. Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Reports. 27: 1472-1486.e5. PMID 31042474 DOI: 10.1016/J.Celrep.2019.04.011 |
0.391 |
|
2019 |
van der Veeken J, Zhong Y, Sharma R, Mazutis L, Dao P, Pe'er D, Leslie CS, Rudensky AY. Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells. Immunity. PMID 31027997 DOI: 10.1016/J.Immuni.2019.03.031 |
0.518 |
|
2019 |
Fleskens V, Minutti CM, Wu X, Wei P, Pals CEGM, McCrae J, Hemmers S, Groenewold V, Vos HJ, Rudensky A, Pan F, Li H, Zaiss DM, Coffer PJ. Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells. Cell Reports. 26: 3600-3612.e6. PMID 30917315 DOI: 10.1016/J.Celrep.2019.02.087 |
0.553 |
|
2019 |
Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/J.Immuni.2018.12.016 |
0.512 |
|
2019 |
Hou S, Clement RL, Diallo A, Blazar BR, Rudensky AY, Sharpe AH, Sage PT. FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program. The Journal of Experimental Medicine. PMID 30705058 DOI: 10.1084/Jem.20181134 |
0.434 |
|
2019 |
Konopacki C, Pritykin Y, Rubtsov Y, Leslie CS, Rudensky AY. Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function. Nature Immunology. PMID 30643266 DOI: 10.1038/S41590-018-0291-Z |
0.583 |
|
2019 |
Glasner A, Zhong Y, Veeken JVD, Rudensky A. Abstract A190: Mechanisms governing Foxp3-dependent and -independent gene expression in regulatory T-cells in evolutionary distant mice Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A190 |
0.534 |
|
2018 |
Fan X, Moltedo B, Mendoza A, Davydov AN, Faire MB, Mazutis L, Sharma R, Pe'er D, Chudakov DM, Rudensky AY. CD49b defines functionally mature Treg cells that survey skin and vascular tissues. The Journal of Experimental Medicine. PMID 30355617 DOI: 10.1084/Jem.20181442 |
0.48 |
|
2018 |
Hsin JP, Lu Y, Loeb GB, Leslie CS, Rudensky AY. The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types. Nature Immunology. PMID 30224821 DOI: 10.1038/S41590-018-0208-X |
0.331 |
|
2018 |
Cho S, Lee HM, Yu IS, Choi YS, Huang HY, Hashemifar SS, Lin LL, Chen MC, Afanasiev ND, Khan AA, Lin SW, Rudensky AY, Crotty S, Lu LF. Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nature Communications. 9: 2757. PMID 30013024 DOI: 10.1038/S41467-018-05196-3 |
0.351 |
|
2018 |
Azizi E, Carr AJ, Plitas G, Cornish AE, Konopacki C, Prabhakaran S, Nainys J, Wu K, Kiseliovas V, Setty M, Choi K, Fromme RM, Dao P, McKenney PT, Wasti RC, ... ... Rudensky AY, et al. Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment. Cell. PMID 29961579 DOI: 10.1016/J.Cell.2018.05.060 |
0.461 |
|
2018 |
Campbell C, Dikiy S, Bhattarai SK, Chinen T, Matheis F, Calafiore M, Hoyos B, Hanash A, Mucida D, Bucci V, Rudensky AY. Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance. Immunity. PMID 29858010 DOI: 10.1016/J.Immuni.2018.04.013 |
0.469 |
|
2018 |
Moore MJ, Blachere NE, Fak JJ, Park CY, Sawicka K, Parveen S, Zucker-Scharff I, Moltedo B, Rudensky AY, Darnell RB. ZFP36 RNA-binding proteins restrain T-cell activation and anti-viral immunity. Elife. 7. PMID 29848443 DOI: 10.7554/Elife.33057 |
0.545 |
|
2018 |
Li K, Vorkas CK, Chaudhry A, Bell DL, Willis RA, Rudensky A, Altman JD, Glickman MS, Aubé J. Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU). Plos One. 13: e0191837. PMID 29401462 DOI: 10.1371/Journal.Pone.0191837 |
0.462 |
|
2018 |
Ariyan CE, Brady MS, Siegelbaum RH, Hu J, Bello DM, Green J, Fisher C, Lefkowitz RA, Panageas KS, Pulitzer M, Vignali M, Emerson R, Tipton C, Robins H, Merghoub T, ... ... Rudensky AY, et al. Robust antitumor responses result from local chemotherapy and CTLA-4 blockade. Cancer Immunology Research. PMID 29339377 DOI: 10.1158/2326-6066.Cir-17-0356 |
0.38 |
|
2018 |
Moore MJ, Blachere NE, Fak JJ, Park CY, Sawicka K, Parveen S, Zucker-Scharff I, Moltedo B, Rudensky AY, Darnell RB. Author response: ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity Elife. DOI: 10.7554/Elife.33057.035 |
0.411 |
|
2017 |
Izraelson M, Nakonechnaya TO, Moltedo B, Egorov ES, Kasatskaya SA, Putintseva EV, Mamedov IZ, Staroverov DB, Shemiakina II, Zakharova MY, Davydov AN, Bolotin DA, Shugay M, Chudakov DM, Rudensky AY, et al. Comparative Analysis of Murine T Cell Receptor Repertoires. Immunology. PMID 29080364 DOI: 10.1111/Imm.12857 |
0.473 |
|
2017 |
Green JA, Arpaia N, Schizas M, Dobrin A, Rudensky AY. A nonimmune function of T cells in promoting lung tumor progression. The Journal of Experimental Medicine. PMID 29038367 DOI: 10.1084/Jem.20170356 |
0.753 |
|
2017 |
Bolotin DA, Poslavsky S, Davydov AN, Frenkel FE, Fanchi L, Zolotareva OI, Hemmers S, Putintseva EV, Obraztsova AS, Shugay M, Ataullakhanov RI, Rudensky AY, Schumacher TN, Chudakov DM. Antigen receptor repertoire profiling from RNA-seq data. Nature Biotechnology. 35: 908-911. PMID 29020005 DOI: 10.1038/Nbt.3979 |
0.347 |
|
2017 |
Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY. Corrigendum: Stability and function of regulatory T cells expressing the transcription factor T-bet. Nature. PMID 28953866 DOI: 10.1038/Nature24013 |
0.504 |
|
2017 |
Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J. BRCT-domain protein BRIT1 influences class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. PMID 28724724 DOI: 10.1073/Pnas.1708211114 |
0.314 |
|
2017 |
Levine AG, Medoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY. Stability and function of regulatory T cells expressing the transcription factor T-bet. Nature. 546: 421-425. PMID 28607488 DOI: 10.1038/Nature22360 |
0.597 |
|
2017 |
Levine AG, Hemmers S, Baptista AP, Schizas M, Faire MB, Moltedo B, Konopacki C, Schmidt-Supprian M, Germain RN, Treuting PM, Rudensky AY. Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity. The Journal of Experimental Medicine. PMID 28130403 DOI: 10.1084/Jem.20161318 |
0.601 |
|
2017 |
Fontenot JD, Gavin MA, Rudensky AY. Pillars Article: Foxp3 Programs the Development and Function of CD4+CD25+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330-336. Journal of Immunology (Baltimore, Md. : 1950). 198: 986-992. PMID 28115587 |
0.711 |
|
2016 |
Vaidyanathan B, Chaudhry A, Yewdell WT, Angeletti D, Yen WF, Wheatley AK, Bradfield CA, McDermott AB, Yewdell JW, Rudensky AY, Chaudhuri J. The aryl hydrocarbon receptor controls cell-fate decisions in B cells. The Journal of Experimental Medicine. PMID 28011866 DOI: 10.1084/Jem.20160789 |
0.449 |
|
2016 |
Sektioglu IM, Carretero R, Bulbuc N, Bald T, Tüting T, Rudensky AY, Hämmerling GJ. Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells. Cancer Research. PMID 27879269 DOI: 10.1158/0008-5472.Can-16-0993 |
0.512 |
|
2016 |
Plitas G, Konopacki C, Wu K, Bos PD, Morrow M, Putintseva EV, Chudakov DM, Rudensky AY. Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer. Immunity. 45: 1122-1134. PMID 27851913 DOI: 10.1016/J.Immuni.2016.10.032 |
0.431 |
|
2016 |
Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Zheng Y, Gasteiger G, Feng Y, Fontenot JD, Rudensky AY. An essential role for the IL-2 receptor in Treg cell function. Nature Immunology. PMID 27595233 DOI: 10.1038/Ni.3540 |
0.788 |
|
2016 |
Plitas G, Rudensky AY. Regulatory T Cells: Differentiation and Function. Cancer Immunology Research. 4: 721-5. PMID 27590281 DOI: 10.1158/2326-6066.Cir-16-0193 |
0.45 |
|
2016 |
van der Veeken J, Gonzalez AJ, Cho H, Arvey A, Hemmers S, Leslie CS, Rudensky AY. Memory of Inflammation in Regulatory T Cells. Cell. PMID 27499023 DOI: 10.1016/J.Cell.2016.07.006 |
0.526 |
|
2016 |
Li MO, Rudensky AY. T cell receptor signalling in the control of regulatory T cell differentiation and function. Nature Reviews. Immunology. 16: 220-33. PMID 27026074 DOI: 10.1038/Nri.2016.26 |
0.554 |
|
2016 |
Fan X, Rudensky AY. Hallmarks of Tissue-Resident Lymphocytes. Cell. 164: 1198-211. PMID 26967286 DOI: 10.1016/J.Cell.2016.02.048 |
0.464 |
|
2016 |
Cho S, Wu CJ, Yasuda T, Cruz LO, Khan AA, Lin LL, Nguyen DT, Miller M, Lee HM, Kuo ML, Broide DH, Rajewsky K, Rudensky AY, Lu LF. miR-23∼27∼24 clusters control effector T cell differentiation and function. The Journal of Experimental Medicine. PMID 26834155 DOI: 10.1084/Jem.20150990 |
0.355 |
|
2016 |
Rudensky AY, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA. Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627. Journal of Immunology (Baltimore, Md. : 1950). 196: 941-6. PMID 26802059 |
0.451 |
|
2016 |
Konopacki C, Plitas G, Rudensky A. Reigning in regulatory T-cell function. Nature Biotechnology. 33: 718-9. PMID 26154011 DOI: 10.1038/Nbt.3285 |
0.507 |
|
2016 |
Plitas G, Wu K, Carlson J, Cimaglia N, Morrow M, Rudensky AY, Wolchok JD. Phase I/II study of mogamulizumab, an anti-CCR4 antibody targeting regulatory T cells in advanced cancer patients. Journal of Clinical Oncology. 34: TPS3098-TPS3098. DOI: 10.1200/Jco.2016.34.15_Suppl.Tps3098 |
0.56 |
|
2016 |
Hu W, Arpaia N, Bos PD, Green J, Rudensky A. Abstract B081: Tissue repair function of regulatory T cells during infection and cancer progression Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B081 |
0.736 |
|
2016 |
Hu W, Arpaia N, Green JA, Hendrickson RC, Rudensky AY. Abstract A072: Glucose metabolism and O-linked GlcNAcylation in the tissue repair function of Treg cells Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A072 |
0.724 |
|
2016 |
Hsin J, Lu Y, Leslie CS, Rudensky AY. Abstract A062: The effects of cellular context on miR-155 mediated regulation of gene expression Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A062 |
0.331 |
|
2016 |
Plitas G, Konopacki C, Wu K, Paula B, Morrow M, Rudensky A. Abstract P4-04-11: Preferential expression of the chemokine receptor 8 (CCR8) on regulatory T cells (Treg) infiltrating human breast cancers represents a novel immunotherapeutic target Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-04-11 |
0.395 |
|
2015 |
Feng Y, van der Veeken J, Shugay M, Putintseva EV, Osmanbeyoglu HU, Dikiy S, Hoyos BE, Moltedo B, Hemmers S, Treuting P, Leslie CS, Chudakov DM, Rudensky AY. A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance. Nature. PMID 26605529 DOI: 10.1038/Nature16141 |
0.586 |
|
2015 |
Liu Z, Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN. Immune homeostasis enforced by co-localized effector and regulatory T cells. Nature. PMID 26605524 DOI: 10.1038/Nature16169 |
0.589 |
|
2015 |
Arvey A, van der Veeken J, Plitas G, Rich SS, Concannon P, Rudensky AY. Genetic and epigenetic variation in the lineage specification of regulatory T cells. Elife. 4. PMID 26510014 DOI: 10.7554/Elife.07571 |
0.453 |
|
2015 |
Gasteiger G, Fan X, Dikiy S, Lee SY, Rudensky AY. Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs. Science (New York, N.Y.). PMID 26472762 DOI: 10.1126/Science.Aac9593 |
0.388 |
|
2015 |
Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH. Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. The Journal of Experimental Medicine. 212: 1603-21. PMID 26371185 DOI: 10.1084/Jem.20141030 |
0.586 |
|
2015 |
Arpaia N, Green JA, Moltedo B, Arvey A, Hemmers S, Yuan S, Treuting PM, Rudensky AY. A Distinct Function of Regulatory T Cells in Tissue Protection. Cell. 162: 1078-89. PMID 26317471 DOI: 10.1016/J.Cell.2015.08.021 |
0.732 |
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2015 |
Feng Y, Rudensky AY. DNA methylation secures CD4(+) and CD8(+) T cell lineage borders. Nature Immunology. 16: 681-3. PMID 26086134 DOI: 10.1038/Ni.3207 |
0.418 |
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2015 |
Hemmers S, Rudensky AY. The Cell-Intrinsic Circadian Clock Is Dispensable for Lymphocyte Differentiation and Function. Cell Reports. 11: 1339-49. PMID 26004187 DOI: 10.1016/J.Celrep.2015.04.058 |
0.47 |
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2015 |
Arvey A, Veeken Jvd, Plitas G, Rich SS, Concannon P, Rudensky AY. Author response: Genetic and epigenetic variation in the lineage specification of regulatory T cells Elife. DOI: 10.7554/Elife.07571.029 |
0.46 |
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2014 |
Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen RS, Stehling-Sun S, Sabo PJ, Byron R, Humbert R, Thurman RE, Johnson AK, Vong S, Lee K, Bates D, ... ... Rudensky A, et al. Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. Science (New York, N.Y.). 346: 1007-12. PMID 25411453 DOI: 10.1126/Science.1246426 |
0.704 |
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2014 |
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, ... ... Rudensky A, et al. A comparative encyclopedia of DNA elements in the mouse genome. Nature. 515: 355-64. PMID 25409824 DOI: 10.1038/Nature13992 |
0.692 |
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2014 |
Levine AG, Arvey A, Jin W, Rudensky AY. Continuous requirement for the TCR in regulatory T cell function. Nature Immunology. 15: 1070-8. PMID 25263123 DOI: 10.1038/Ni.3004 |
0.59 |
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2014 |
Gasteiger G, Rudensky AY. Interactions between innate and adaptive lymphocytes. Nature Reviews. Immunology. 14: 631-9. PMID 25132095 DOI: 10.1038/Nri3726 |
0.47 |
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2014 |
Feng Y, Arvey A, Chinen T, van der Veeken J, Gasteiger G, Rudensky AY. Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus. Cell. 158: 749-63. PMID 25126783 DOI: 10.1016/J.Cell.2014.07.031 |
0.534 |
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2014 |
Penaloza-MacMaster P, Kamphorst AO, Wieland A, Araki K, Iyer SS, West EE, O'Mara L, Yang S, Konieczny BT, Sharpe AH, Freeman GJ, Rudensky AY, Ahmed R. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. The Journal of Experimental Medicine. 211: 1905-18. PMID 25113973 DOI: 10.1084/Jem.20132577 |
0.553 |
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2014 |
Arvey A, van der Veeken J, Samstein RM, Feng Y, Stamatoyannopoulos JA, Rudensky AY. Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells. Nature Immunology. 15: 580-7. PMID 24728351 DOI: 10.1038/Ni.2868 |
0.475 |
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2014 |
Moltedo B, Hemmers S, Rudensky AY. Regulatory T cell ablation causes acute T cell lymphopenia. Plos One. 9: e86762. PMID 24466225 DOI: 10.1371/Journal.Pone.0086762 |
0.578 |
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2014 |
Arpaia N, Rudensky AY. Microbial metabolites control gut inflammatory responses. Proceedings of the National Academy of Sciences of the United States of America. 111: 2058-9. PMID 24434557 DOI: 10.1073/Pnas.1323183111 |
0.647 |
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2013 |
van der Veeken J, Arvey A, Rudensky A. Transcriptional control of regulatory T-cell differentiation. Cold Spring Harbor Symposia On Quantitative Biology. 78: 215-22. PMID 24733379 DOI: 10.1101/Sqb.2013.78.020289 |
0.523 |
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2013 |
Arpaia N, Campbell C, Fan X, Dikiy S, van der Veeken J, deRoos P, Liu H, Cross JR, Pfeffer K, Coffer PJ, Rudensky AY. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature. 504: 451-5. PMID 24226773 DOI: 10.1038/Nature12726 |
0.73 |
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2013 |
Bos PD, Plitas G, Rudra D, Lee SY, Rudensky AY. Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy. The Journal of Experimental Medicine. 210: 2435-66. PMID 24127486 DOI: 10.1084/Jem.20130762 |
0.504 |
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2013 |
Sakaguchi S, Vignali DA, Rudensky AY, Niec RE, Waldmann H. The plasticity and stability of regulatory T cells. Nature Reviews. Immunology. 13: 461-7. PMID 23681097 DOI: 10.1038/Nri3464 |
0.577 |
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2013 |
Gasteiger G, Hemmers S, Firth MA, Le Floc'h A, Huse M, Sun JC, Rudensky AY. IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells. The Journal of Experimental Medicine. 210: 1167-78. PMID 23650441 DOI: 10.1084/Jem.20122462 |
0.543 |
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2013 |
Gasteiger G, Hemmers S, Bos PD, Sun JC, Rudensky AY. IL-2-dependent adaptive control of NK cell homeostasis. The Journal of Experimental Medicine. 210: 1179-87. PMID 23650439 DOI: 10.1084/Jem.20122571 |
0.544 |
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2013 |
Zawislak CL, Beaulieu AM, Loeb GB, Karo J, Canner D, Bezman NA, Lanier LL, Rudensky AY, Sun JC. Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155. Proceedings of the National Academy of Sciences of the United States of America. 110: 6967-72. PMID 23572582 DOI: 10.1073/Pnas.1304410110 |
0.379 |
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2013 |
Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF. Regulatory T cells: recommendations to simplify the nomenclature. Nature Immunology. 14: 307-8. PMID 23507634 DOI: 10.1038/Ni.2554 |
0.562 |
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2013 |
Chaudhry A, Rudensky AY. Control of inflammation by integration of environmental cues by regulatory T cells. The Journal of Clinical Investigation. 123: 939-44. PMID 23454755 DOI: 10.1172/Jci57175 |
0.444 |
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2012 |
Bos PD, Rudensky AY. Treg cells in cancer: a case of multiple personality disorder. Science Translational Medicine. 4: 164fs44. PMID 23241741 DOI: 10.1126/Scitranslmed.3005283 |
0.395 |
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2012 |
Ouyang W, Liao W, Luo CT, Yin N, Huse M, Kim MV, Peng M, Chan P, Ma Q, Mo Y, Meijer D, Zhao K, Rudensky AY, Atwal G, Zhang MQ, et al. Novel Foxo1-dependent transcriptional programs control T(reg) cell function. Nature. 491: 554-9. PMID 23135404 DOI: 10.1038/Nature11581 |
0.586 |
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2012 |
Samstein RM, Arvey A, Josefowicz SZ, Peng X, Reynolds A, Sandstrom R, Neph S, Sabo P, Kim JM, Liao W, Li MO, Leslie C, Stamatoyannopoulos JA, Rudensky AY. Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification. Cell. 151: 153-66. PMID 23021222 DOI: 10.1016/J.Cell.2012.06.053 |
0.811 |
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2012 |
Weiss JM, Bilate AM, Gobert M, Ding Y, Curotto de Lafaille MA, Parkhurst CN, Xiong H, Dolpady J, Frey AB, Ruocco MG, Yang Y, Floess S, Huehn J, Oh S, Li MO, ... ... Rudensky AY, et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. The Journal of Experimental Medicine. 209: 1723-42, S1. PMID 22966001 DOI: 10.1084/Jem.20120914 |
0.568 |
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2012 |
Rudra D, deRoos P, Chaudhry A, Niec RE, Arvey A, Samstein RM, Leslie C, Shaffer SA, Goodlett DR, Rudensky AY. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nature Immunology. 13: 1010-9. PMID 22922362 DOI: 10.1038/Ni.2402 |
0.458 |
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2012 |
Samstein RM, Josefowicz SZ, Arvey A, Treuting PM, Rudensky AY. Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict. Cell. 150: 29-38. PMID 22770213 DOI: 10.1016/J.Cell.2012.05.031 |
0.768 |
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2012 |
Darce J, Rudra D, Li L, Nishio J, Cipolletta D, Rudensky AY, Mathis D, Benoist C. An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes. Immunity. 36: 731-41. PMID 22579475 DOI: 10.1016/J.Immuni.2012.04.007 |
0.507 |
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2012 |
Josefowicz SZ, Niec RE, Kim HY, Treuting P, Chinen T, Zheng Y, Umetsu DT, Rudensky AY. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature. 482: 395-9. PMID 22318520 DOI: 10.1038/Nature10772 |
0.823 |
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2012 |
Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annual Review of Immunology. 30: 531-64. PMID 22224781 DOI: 10.1146/Annurev.Immunol.25.022106.141623 |
0.785 |
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2011 |
Rudensky AY, Chervonsky AV. A narrow circle of mutual friends. Immunity. 34: 697-9. PMID 21616440 DOI: 10.1016/J.Immuni.2011.05.008 |
0.36 |
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2011 |
Chaudhry A, Samstein RM, Treuting P, Liang Y, Pils MC, Heinrich JM, Jack RS, Wunderlich FT, Brüning JC, Müller W, Rudensky AY. Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity. 34: 566-78. PMID 21511185 DOI: 10.1016/J.Immuni.2011.03.018 |
0.519 |
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2011 |
Huber S, Gagliani N, Esplugues E, O'Connor W, Huber FJ, Chaudhry A, Kamanaka M, Kobayashi Y, Booth CJ, Rudensky AY, Roncarolo MG, Battaglia M, Flavell RA. Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity. 34: 554-65. PMID 21511184 DOI: 10.1016/J.Immuni.2011.01.020 |
0.447 |
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2011 |
Rudensky AY. Regulatory T cells and Foxp3. Immunological Reviews. 241: 260-8. PMID 21488902 DOI: 10.1111/J.1600-065X.2011.01018.X |
0.529 |
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2011 |
Sekiya T, Kashiwagi I, Inoue N, Morita R, Hori S, Waldmann H, Rudensky AY, Ichinose H, Metzger D, Chambon P, Yoshimura A. The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nature Communications. 2: 269. PMID 21468021 DOI: 10.1038/Ncomms1272 |
0.575 |
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2011 |
Gutcher I, Donkor MK, Ma Q, Rudensky AY, Flavell RA, Li MO. Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation. Immunity. 34: 396-408. PMID 21435587 DOI: 10.1016/J.Immuni.2011.03.005 |
0.512 |
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2010 |
Rubtsov YP, Niec RE, Josefowicz S, Li L, Darce J, Mathis D, Benoist C, Rudensky AY. Stability of the regulatory T cell lineage in vivo. Science (New York, N.Y.). 329: 1667-71. PMID 20929851 DOI: 10.1126/Science.1191996 |
0.815 |
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2010 |
Chinen T, Volchkov PY, Chervonsky AV, Rudensky AY. A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota. The Journal of Experimental Medicine. 207: 2323-30. PMID 20921284 DOI: 10.1084/Jem.20101235 |
0.596 |
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2010 |
Grainger JR, Smith KA, Hewitson JP, McSorley HJ, Harcus Y, Filbey KJ, Finney CA, Greenwood EJ, Knox DP, Wilson MS, Belkaid Y, Rudensky AY, Maizels RM. Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway. The Journal of Experimental Medicine. 207: 2331-41. PMID 20876311 DOI: 10.1084/Jem.20101074 |
0.496 |
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2010 |
Lu LF, Boldin MP, Chaudhry A, Lin LL, Taganov KD, Hanada T, Yoshimura A, Baltimore D, Rudensky AY. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell. 142: 914-29. PMID 20850013 DOI: 10.1016/J.Cell.2010.08.012 |
0.393 |
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2010 |
Littman DR, Rudensky AY. Th17 and regulatory T cells in mediating and restraining inflammation. Cell. 140: 845-58. PMID 20303875 DOI: 10.1016/J.Cell.2010.02.021 |
0.453 |
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2010 |
Suthar MS, Ma DY, Thomas S, Lund JM, Zhang N, Daffis S, Rudensky AY, Bevan MJ, Clark EA, Kaja MK, Diamond MS, Gale M. IPS-1 is essential for the control of West Nile virus infection and immunity. Plos Pathogens. 6: e1000757. PMID 20140199 DOI: 10.1371/Journal.Ppat.1000757 |
0.397 |
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2010 |
Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature. 463: 808-12. PMID 20072126 DOI: 10.1038/Nature08750 |
0.83 |
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2010 |
Hsing LC, Kirk EA, McMillen TS, Hsiao SH, Caldwell M, Houston B, Rudensky AY, LeBoeuf RC. Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse. Journal of Autoimmunity. 34: 96-104. PMID 19664906 DOI: 10.1016/J.Jaut.2009.07.003 |
0.793 |
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2009 |
Kim J, Lahl K, Hori S, Loddenkemper C, Chaudhry A, deRoos P, Rudensky A, Sparwasser T. Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 7631-4. PMID 19923467 DOI: 10.4049/Jimmunol.0804308 |
0.531 |
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2009 |
Lanteri MC, O'Brien KM, Purtha WE, Cameron MJ, Lund JM, Owen RE, Heitman JW, Custer B, Hirschkorn DF, Tobler LH, Kiely N, Prince HE, Ndhlovu LC, Nixon DF, Kamel HT, ... ... Rudensky AY, et al. Tregs control the development of symptomatic West Nile virus infection in humans and mice. The Journal of Clinical Investigation. 119: 3266-77. PMID 19855131 DOI: 10.1172/Jci39387 |
0.322 |
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2009 |
Chaudhry A, Rudra D, Treuting P, Samstein RM, Liang Y, Kas A, Rudensky AY. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. Science (New York, N.Y.). 326: 986-91. PMID 19797626 DOI: 10.1126/Science.1172702 |
0.543 |
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2009 |
Rudra D, Egawa T, Chong MM, Treuting P, Littman DR, Rudensky AY. Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells. Nature Immunology. 10: 1170-7. PMID 19767756 DOI: 10.1038/Ni.1795 |
0.573 |
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2009 |
Darrasse-Jèze G, Deroubaix S, Mouquet H, Victora GD, Eisenreich T, Yao KH, Masilamani RF, Dustin ML, Rudensky A, Liu K, Nussenzweig MC. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. The Journal of Experimental Medicine. 206: 1853-62. PMID 19667061 DOI: 10.1084/Jem.20090746 |
0.58 |
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2009 |
Lu L, Rudensky A. Molecular orchestration of differentiation and function of regulatory T cells Genes & Development. 23: 1270-1282. PMID 19487568 DOI: 10.1101/Gad.1791009 |
0.531 |
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2009 |
Josefowicz SZ, Rudensky A. Control of regulatory T cell lineage commitment and maintenance. Immunity. 30: 616-25. PMID 19464984 DOI: 10.1016/J.Immuni.2009.04.009 |
0.818 |
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2009 |
Josefowicz SZ, Wilson CB, Rudensky AY. Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. Journal of Immunology (Baltimore, Md. : 1950). 182: 6648-52. PMID 19454658 DOI: 10.4049/Jimmunol.0803320 |
0.777 |
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2009 |
Bautista JL, Lio CW, Lathrop SK, Forbush K, Liang Y, Luo J, Rudensky AY, Hsieh CS. Intraclonal competition limits the fate determination of regulatory T cells in the thymus. Nature Immunology. 10: 610-7. PMID 19430476 DOI: 10.1038/Ni.1739 |
0.584 |
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2009 |
Weaver CT, Rudensky AY. Editorial overview: lymphocyte development. Current Opinion in Immunology. 21: 119-20. PMID 19361970 DOI: 10.1016/J.Coi.2009.03.007 |
0.318 |
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2009 |
Liu K, Victora GD, Schwickert TA, Guermonprez P, Meredith MM, Yao K, Chu FF, Randolph GJ, Rudensky AY, Nussenzweig M. In vivo analysis of dendritic cell development and homeostasis. Science (New York, N.Y.). 324: 392-7. PMID 19286519 DOI: 10.1126/Science.1170540 |
0.357 |
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2009 |
Zheng Y, Chaudhry A, Kas A, deRoos P, Kim JM, Chu TT, Corcoran L, Treuting P, Klein U, Rudensky AY. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature. 458: 351-6. PMID 19182775 DOI: 10.1038/Nature07674 |
0.687 |
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2009 |
Lu LF, Thai TH, Calado DP, Chaudhry A, Kubo M, Tanaka K, Loeb GB, Lee H, Yoshimura A, Rajewsky K, Rudensky AY. Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein Immunity. 30: 80-91. PMID 19144316 DOI: 10.1016/J.Immuni.2008.11.010 |
0.449 |
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2008 |
Chong MM, Rasmussen JP, Rudensky AY, Rundensky AY, Littman DR. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. The Journal of Experimental Medicine. 205: 2005-17. PMID 18725527 DOI: 10.1084/Jem.20081219 |
0.473 |
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2008 |
Liston A, Lu LF, O'Carroll D, Tarakhovsky A, Rudensky AY. Dicer-dependent microRNA pathway safeguards regulatory T cell function. The Journal of Experimental Medicine. 205: 1993-2004. PMID 18725526 DOI: 10.1084/Jem.20081062 |
0.538 |
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2008 |
Liston A, Nutsch KM, Farr AG, Lund JM, Rasmussen JP, Koni PA, Rudensky AY. Differentiation of regulatory Foxp3+ T cells in the thymic cortex. Proceedings of the National Academy of Sciences of the United States of America. 105: 11903-8. PMID 18695219 DOI: 10.1073/Pnas.0801506105 |
0.557 |
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2008 |
Lund JM, Hsing L, Pham TT, Rudensky AY. Coordination of early protective immunity to viral infection by regulatory T cells. Science (New York, N.Y.). 320: 1220-4. PMID 18436744 DOI: 10.1126/Science.1155209 |
0.811 |
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2008 |
Rubtsov YP, Rasmussen JP, Chi EY, Fontenot J, Castelli L, Ye X, Treuting P, Siewe L, Roers A, Henderson WR, Muller W, Rudensky AY. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity. 28: 546-58. PMID 18387831 DOI: 10.1016/J.Immuni.2008.02.017 |
0.778 |
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2008 |
Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, Victora GD, Shen Y, Du J, Rubtsov YP, Rudensky AY, Ziegler SF, Littman DR. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature. 453: 236-40. PMID 18368049 DOI: 10.1038/Nature06878 |
0.506 |
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2008 |
Chong MMW, Rasmussen JP, Rudensky AY, Littman DR. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (Journal of Experimental Medicine (2008) 205, 9 (2005-2017)) Journal of Experimental Medicine. 205: 2449. DOI: 10.1084/jem.20071219090508c |
0.315 |
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2007 |
Lu LF, Gavin MA, Rasmussen JP, Rudensky AY. G protein-coupled receptor 83 is dispensable for the development and function of regulatory T cells. Molecular and Cellular Biology. 27: 8065-72. PMID 17893329 DOI: 10.1128/Mcb.01075-07 |
0.573 |
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2007 |
Scott-Browne JP, Shafiani S, Tucker-Heard G, Ishida-Tsubota K, Fontenot JD, Rudensky AY, Bevan MJ, Urdahl KB. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. The Journal of Experimental Medicine. 204: 2159-69. PMID 17709423 DOI: 10.1084/Jem.20062105 |
0.797 |
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2007 |
Maynard CL, Harrington LE, Janowski KM, Oliver JR, Zindl CL, Rudensky AY, Weaver CT. Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10. Nature Immunology. 8: 931-41. PMID 17694059 DOI: 10.1038/Ni1504 |
0.49 |
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2007 |
Sever S, Altintas MM, Nankoe SR, Möller CC, Ko D, Wei C, Henderson J, del Re EC, Hsing L, Erickson A, Cohen CD, Kretzler M, Kerjaschki D, Rudensky A, Nikolic B, et al. Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. The Journal of Clinical Investigation. 117: 2095-104. PMID 17671649 DOI: 10.1172/Jci32022 |
0.756 |
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2007 |
Sather BD, Treuting P, Perdue N, Miazgowicz M, Fontenot JD, Rudensky AY, Campbell DJ. Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease. The Journal of Experimental Medicine. 204: 1335-47. PMID 17548521 DOI: 10.1084/Jem.20070081 |
0.79 |
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2007 |
Rubtsov YP, Rudensky AY. TGFbeta signalling in control of T-cell-mediated self-reactivity. Nature Reviews. Immunology. 7: 443-53. PMID 17525753 DOI: 10.1038/Nri2095 |
0.532 |
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2007 |
Zheng Y, Rudensky AY. Foxp3 in control of the regulatory T cell lineage. Nature Immunology. 8: 457-62. PMID 17440451 DOI: 10.1038/Ni1455 |
0.678 |
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2007 |
van der Vliet HJ, van der Vliet HJ, Koon HB, Yue SC, Uzunparmak B, Seery V, Gavin MA, Rudensky AY, Atkins MB, Balk SP, Exley MA. Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2100-8. PMID 17404092 DOI: 10.1158/1078-0432.Ccr-06-1662 |
0.382 |
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2007 |
Henderson WR, Chi EY, Bollinger JG, Tien YT, Ye X, Castelli L, Rubtsov YP, Singer AG, Chiang GK, Nevalainen T, Rudensky AY, Gelb MH. Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model. The Journal of Experimental Medicine. 204: 865-77. PMID 17403936 DOI: 10.1084/Jem.20070029 |
0.38 |
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2007 |
Denning TL, Granger SW, Granger S, Mucida D, Graddy R, Leclercq G, Zhang W, Honey K, Rasmussen JP, Cheroutre H, Rudensky AY, Kronenberg M. Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. Journal of Immunology (Baltimore, Md. : 1950). 178: 4230-9. PMID 17371979 DOI: 10.4049/Jimmunol.178.7.4230 |
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2007 |
Liston A, Farr AG, Chen Z, Benoist C, Mathis D, Manley NR, Rudensky AY. Lack of Foxp3 function and expression in the thymic epithelium. The Journal of Experimental Medicine. 204: 475-80. PMID 17353370 DOI: 10.1084/Jem.20062465 |
0.58 |
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2007 |
Liston A, Rudensky AY. Thymic development and peripheral homeostasis of regulatory T cells. Current Opinion in Immunology. 19: 176-85. PMID 17306520 DOI: 10.1016/J.Coi.2007.02.005 |
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2007 |
Zheng Y, Josefowicz SZ, Kas A, Chu TT, Gavin MA, Rudensky AY. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature. 445: 936-40. PMID 17237761 DOI: 10.1038/Nature05563 |
0.808 |
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2007 |
Williams LM, Rudensky AY. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nature Immunology. 8: 277-84. PMID 17220892 DOI: 10.1038/Ni1437 |
0.818 |
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2007 |
Gavin MA, Rasmussen JP, Fontenot JD, Vasta V, Manganiello VC, Beavo JA, Rudensky AY. Foxp3-dependent programme of regulatory T-cell differentiation. Nature. 445: 771-5. PMID 17220874 DOI: 10.1038/Nature05543 |
0.796 |
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2007 |
Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nature Immunology. 8: 191-7. PMID 17136045 DOI: 10.1038/Ni1428 |
0.559 |
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2006 |
Marie JC, Liggitt D, Rudensky AY. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity. 25: 441-54. PMID 16973387 DOI: 10.1016/J.Immuni.2006.07.012 |
0.479 |
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2006 |
Kim JM, Rudensky A. The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunological Reviews. 212: 86-98. PMID 16903908 DOI: 10.1111/J.0105-2896.2006.00426.X |
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2006 |
Rudensky AY, Gavin M, Zheng Y. FOXP3 and NFAT: partners in tolerance. Cell. 126: 253-6. PMID 16873058 DOI: 10.1016/J.Cell.2006.07.005 |
0.688 |
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2006 |
Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proceedings of the National Academy of Sciences of the United States of America. 103: 6659-64. PMID 16617117 DOI: 10.1073/Pnas.0509484103 |
0.558 |
|
2006 |
Rudensky AY, Campbell DJ. In vivo sites and cellular mechanisms of T reg cell-mediated suppression. The Journal of Experimental Medicine. 203: 489-92. PMID 16533888 DOI: 10.1084/Jem.20060214 |
0.586 |
|
2006 |
Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nature Immunology. 7: 401-10. PMID 16532000 DOI: 10.1038/Ni1318 |
0.829 |
|
2006 |
Rudensky A, Beers C. Lysosomal cysteine proteases and antigen presentation. Ernst Schering Research Foundation Workshop. 81-95. PMID 16329647 DOI: 10.1007/3-540-37673-9_5 |
0.334 |
|
2006 |
Rudensky A. Foxp3 and dominant tolerance. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 360: 1645-6. PMID 16147528 DOI: 10.1098/Rstb.2005.1731 |
0.382 |
|
2006 |
Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. Erratum: A function for interleukin 2 in Foxp3-expressing regulatory T cells Nature Immunology. 7: 427-427. DOI: 10.1038/Ni0406-427B |
0.73 |
|
2006 |
Sather BD, Gyarmati D, Miazgowicz M, Fontenot JD, Rudensky AY, Campbell DJ. Su.135. Regulatory T-Cell Expression of CCR4 is Required to Prevent Cutaneous & Pulmonary Inflammation Clinical Immunology. 119: S206. DOI: 10.1016/J.Clim.2006.04.562 |
0.765 |
|
2005 |
Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nature Immunology. 6: 1142-51. PMID 16227984 DOI: 10.1038/Ni1263 |
0.771 |
|
2005 |
Fontenot JD, Dooley JL, Farr AG, Rudensky AY. Developmental regulation of Foxp3 expression during ontogeny Journal of Experimental Medicine. 202: 901-906. PMID 16203863 DOI: 10.1084/Jem.20050784 |
0.798 |
|
2005 |
Hsing LC, Rudensky AY. The lysosomal cysteine proteases in MHC class II antigen presentation. Immunological Reviews. 207: 229-41. PMID 16181340 DOI: 10.1111/J.0105-2896.2005.00310.X |
0.808 |
|
2005 |
Quezada SA, Bennett K, Blazar BR, Rudensky AY, Sakaguchi S, Noelle RJ. Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation. Journal of Immunology (Baltimore, Md. : 1950). 175: 771-9. PMID 16002673 DOI: 10.4049/Jimmunol.175.2.771 |
0.542 |
|
2005 |
Hsieh CS, Rudensky AY. The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology. Current Topics in Microbiology and Immunology. 293: 25-42. PMID 15981474 DOI: 10.1007/3-540-27702-1_2 |
0.506 |
|
2005 |
Kronenberg M, Rudensky A. Regulation of immunity by self-reactive T cells Nature. 435: 598-604. PMID 15931212 DOI: 10.1038/Nature03725 |
0.455 |
|
2005 |
Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. The Journal of Experimental Medicine. 201: 1061-7. PMID 15809351 DOI: 10.1084/Jem.20042276 |
0.472 |
|
2005 |
Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nature Immunology. 6: 331-7. PMID 15785758 DOI: 10.1038/Ni1179 |
0.807 |
|
2005 |
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity. 22: 329-41. PMID 15780990 DOI: 10.1016/J.Immuni.2005.01.016 |
0.86 |
|
2005 |
Beers C, Burich A, Kleijmeer MJ, Griffith JM, Wong P, Rudensky AY. Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 174: 1205-12. PMID 15661874 DOI: 10.4049/Jimmunol.174.3.1205 |
0.826 |
|
2005 |
Taylor PA, Panoskaltsis-Mortari A, Freeman GJ, Sharpe AH, Noelle RJ, Rudensky AY, Mak TW, Serody JS, Blazar BR. Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM). Blood. 105: 3372-80. PMID 15618467 DOI: 10.1182/Blood-2004-10-3869 |
0.55 |
|
2004 |
Hsieh CS, Liang Y, Tyznik AJ, Self SG, Liggitt D, Rudensky AY. Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity. 21: 267-77. PMID 15308106 DOI: 10.1016/J.Immuni.2004.07.009 |
0.471 |
|
2004 |
Fontenot JD, Rudensky AY. Molecular aspects of regulatory T cell development. Seminars in Immunology. 16: 73-80. PMID 15036230 DOI: 10.1016/J.Smim.2003.12.002 |
0.804 |
|
2004 |
Honey K, Forbush K, Jensen PE, Rudensky AY. Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M. Journal of Immunology (Baltimore, Md. : 1950). 172: 4142-50. PMID 15034026 DOI: 10.4049/Jimmunol.172.7.4142 |
0.347 |
|
2004 |
Taylor P, Panoskaltsis-Mortari A, Freeman G, Sharpe A, Noelle R, Rudensky A, Mak T, Serody J, Blazar B. The ICOS:ICOSL Costimulatory Pathway Plays an Important Role in GVHD and Bone Marrow (BM) Graft Rejection. Blood. 104: 591-591. DOI: 10.1182/Blood.V104.11.591.591 |
0.506 |
|
2004 |
Taylor P, Panoskaltsis-Mortari A, Noelle R, Rudensky A, Serody J, Blazar B. Visualizing Allogeneic Bone Marrow (BM) Graft Rejection. Blood. 104: 43-43. DOI: 10.1182/Blood.V104.11.43.43 |
0.494 |
|
2003 |
Gavin M, Rudensky A. Control of immune homeostasis by naturally arising regulatory CD4+ T cells Current Opinion in Immunology. 15: 690-696. PMID 14630204 DOI: 10.1016/J.Coi.2003.09.011 |
0.503 |
|
2003 |
Itano AA, McSorley SJ, Reinhardt RL, Ehst BD, Ingulli E, Rudensky AY, Jenkins MK. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity. 19: 47-57. PMID 12871638 DOI: 10.1016/S1074-7613(03)00175-4 |
0.534 |
|
2003 |
Honey K, Rudensky AY. Lysosomal cysteine proteases regulate antigen presentation. Nature Reviews. Immunology. 3: 472-82. PMID 12776207 DOI: 10.1038/Nri1110 |
0.36 |
|
2003 |
Quezada SA, Fuller B, Jarvinen LZ, Gonzalez M, Blazar BR, Rudensky AY, Strom TB, Noelle RJ. Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation. Blood. 102: 1920-6. PMID 12750162 DOI: 10.1182/Blood-2003-02-0586 |
0.48 |
|
2003 |
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nature Immunology. 4: 330-6. PMID 12612578 DOI: 10.1038/Ni904 |
0.745 |
|
2003 |
Zhu Y, Rudensky AY, Corper AL, Teyton L, Wilson IA. Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. Journal of Molecular Biology. 326: 1157-74. PMID 12589760 DOI: 10.1016/S0022-2836(02)01437-7 |
0.329 |
|
2003 |
Beers C, Honey K, Fink S, Forbush K, Rudensky A. Differential regulation of cathepsin S and cathepsin L in interferon gamma-treated macrophages. The Journal of Experimental Medicine. 197: 169-79. PMID 12538657 DOI: 10.1084/Jem.20020978 |
0.782 |
|
2002 |
Firpo EJ, Kong RK, Zhou Q, Rudensky AY, Roberts JM, Franza BR. Antigen-specific dose-dependent system for the study of an inheritable and reversible phenotype in mouse CD4+ T cells. Immunology. 107: 480-8. PMID 12460193 DOI: 10.1046/J.1365-2567.2002.01540.X |
0.514 |
|
2002 |
Gonzalez M, Quezada SA, Blazar BR, Panoskaltsis-Mortari A, Rudensky AY, Noelle RJ. The balance between donor T cell anergy and suppression versus lethal graft-versus-host disease is determined by host conditioning. Journal of Immunology (Baltimore, Md. : 1950). 169: 5581-9. PMID 12421935 DOI: 10.4049/Jimmunol.169.10.5581 |
0.533 |
|
2002 |
Erickson M, Morkowski S, Lehar S, Gillard G, Beers C, Dooley J, Rubin JS, Rudensky A, Farr AG. Regulation of thymic epithelium by keratinocyte growth factor. Blood. 100: 3269-78. PMID 12384427 DOI: 10.1182/Blood-2002-04-1036 |
0.773 |
|
2002 |
Honey K, Benlagha K, Beers C, Forbush K, Teyton L, Kleijmeer MJ, Rudensky AY, Bendelac A. Thymocyte expression of cathepsin L is essential for NKT cell development. Nature Immunology. 3: 1069-74. PMID 12368909 DOI: 10.1038/Ni844 |
0.811 |
|
2002 |
Sun M, Richards S, Prasad DV, Mai XM, Rudensky A, Dong C. Characterization of mouse and human B7-H3 genes. Journal of Immunology (Baltimore, Md. : 1950). 168: 6294-7. PMID 12055244 DOI: 10.4049/Jimmunol.168.12.6294 |
0.387 |
|
2002 |
Honey K, Nakagawa T, Peters C, Rudensky A. Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands. The Journal of Experimental Medicine. 195: 1349-58. PMID 12021314 DOI: 10.1084/Jem.20011904 |
0.518 |
|
2002 |
Barton GM, Beers C, deRoos P, Eastman SR, Gomez ME, Forbush KA, Rudensky AY. Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 6937-42. PMID 12011451 DOI: 10.1073/Pnas.102645699 |
0.825 |
|
2002 |
Hsieh CS, deRoos P, Honey K, Beers C, Rudensky AY. A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. Journal of Immunology (Baltimore, Md. : 1950). 168: 2618-25. PMID 11884425 DOI: 10.4049/Jimmunol.168.6.2618 |
0.764 |
|
2002 |
Gavin MA, Rudensky AY. Dual TCR T cells: gaining entry into the periphery. Nature Immunology. 3: 109-10. PMID 11812982 DOI: 10.1038/Ni0202-109 |
0.569 |
|
2002 |
Gavin MA, Clarke SR, Negrou E, Gallegos A, Rudensky A. Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo Nature Immunology. 3: 33-41. PMID 11740498 DOI: 10.1038/Ni743 |
0.546 |
|
2001 |
Kleijmeer M, Ramm G, Schuurhuis D, Griffith J, Rescigno M, Ricciardi-Castagnoli P, Rudensky AY, Ossendorp F, Melief CJ, Stoorvogel W, Geuze HJ. Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. The Journal of Cell Biology. 155: 53-63. PMID 11581285 DOI: 10.1083/Jcb.200103071 |
0.393 |
|
2001 |
Honey K, Rudensky A. The pIV-otal class II transactivator promoter regulates major histocompatibility complex class II expression in the thymus. The Journal of Experimental Medicine. 194: F15-8. PMID 11514611 DOI: 10.1084/Jem.194.4.F15 |
0.443 |
|
2001 |
Mukherjee P, Dani A, Bhatia S, Singh N, Rudensky AY, George A, Bal V, Mayor S, Rath S. Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis Journal of Immunology. 167: 2632-2641. PMID 11509605 DOI: 10.4049/Jimmunol.167.5.2632 |
0.34 |
|
2001 |
Dongre AR, Kovats S, deRoos P, McCormack AL, Nakagawa T, Paharkova-Vatchkova V, Eng J, Caldwell H, Yates JR, Rudensky AY. In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses. European Journal of Immunology. 31: 1485-94. PMID 11465105 DOI: 10.1002/1521-4141(200105)31:5<1485::Aid-Immu1485>3.0.Co;2-A |
0.467 |
|
2001 |
Benavides F, Venables A, Poetschke Klug H, Glasscock E, Rudensky A, Gómez M, Martin Palenzuela N, Guénet JL, Richie ER, Conti CJ. The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene. Immunogenetics. 53: 233-42. PMID 11398968 DOI: 10.1007/S002510100320 |
0.494 |
|
2001 |
Wong P, Barton GM, Forbush KA, Rudensky AY. Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands Journal of Experimental Medicine. 193: 1179-1187. PMID 11369789 DOI: 10.1084/Jem.193.10.1179 |
0.842 |
|
2001 |
Honey K, Duff M, Beers C, Brissette WH, Elliott EA, Peters C, Maric M, Cresswell P, Rudensky A. Cathepsin S regulates the expression of cathepsin L and the turnover of gamma-interferon-inducible lysosomal thiol reductase in B lymphocytes. The Journal of Biological Chemistry. 276: 22573-8. PMID 11306582 DOI: 10.1074/Jbc.M101851200 |
0.797 |
|
2000 |
Clarke SR, Rudensky AY. Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes. Journal of Immunology (Baltimore, Md. : 1950). 165: 2458-64. PMID 10946271 DOI: 10.4049/Jimmunol.165.5.2458 |
0.582 |
|
2000 |
Wong P, Goldrath AW, Rudensky AY. Competition for specific intrathymic ligands limits positive selection in a TCR transgenic model of CD4+ T cell development. Journal of Immunology (Baltimore, Md. : 1950). 164: 6252-9. PMID 10843678 DOI: 10.4049/Jimmunol.164.12.6252 |
0.694 |
|
2000 |
Nakagawa TY, Rudensky AY. The role of lysosomal proteinases in MHC class II-mediated antigen processing and presentation. Immunological Reviews. 172: 121-9. PMID 10631942 DOI: 10.1111/J.1600-065X.1999.Tb01361.X |
0.517 |
|
2000 |
Underhill DM, Bassetti M, Rudensky A, Aderem A. Dynamic interactions of macrophages with T cells during antigen presentation. The Journal of Experimental Medicine. 190: 1909-14. PMID 10601366 DOI: 10.1084/Jem.190.12.1909 |
0.541 |
|
1999 |
Barton GM, Rudensky AY. Evaluating peptide repertoires within the context of thymocyte development Seminars in Immunology. 11: 417-422. PMID 10625595 DOI: 10.1006/Smim.1999.0199 |
0.776 |
|
1999 |
Nakagawa TY, Brissette WH, Lira PD, Griffiths RJ, Petrushova N, Stock J, McNeish JD, Eastman SE, Howard ED, Clarke SR, Rosloniec EF, Elliott EA, Rudensky AY. Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity. 10: 207-17. PMID 10072073 DOI: 10.1016/S1074-7613(00)80021-7 |
0.399 |
|
1999 |
Morkowski S, Raposo G, Geuze HJ, Rudensky AY. Peptide loading in the endoplasmic reticulum accelerates trafficking of peptide:MHC class II complexes in B cells. Journal of Biomedical Science. 6: 53-63. PMID 9933743 DOI: 10.1007/Bf02256424 |
0.395 |
|
1999 |
Barton GM, Rudensky AY. Requirement for diverse, low-abundance peptides in positive selection of T cells Science. 283: 67-70. PMID 9872742 DOI: 10.1126/Science.283.5398.67 |
0.797 |
|
1999 |
Rudensky A. Role of self peptides in T-cell development in the thymus Biomedicine & Pharmacotherapy. 53: 445. DOI: 10.1016/S0753-3322(99)80126-7 |
0.377 |
|
1998 |
Barton GM, Rudensky AY. An altered invariant chain protein with an antigenic peptide in place of CLIP forms SDS-stable complexes with class II αβ dimers and facilitates highly efficient peptide loading International Immunology. 10: 1159-1165. PMID 9723702 DOI: 10.1093/Intimm/10.8.1159 |
0.721 |
|
1998 |
Chervonsky AV, Medzhitov RM, Denzin LK, Barlow AK, Rudensky AY, Janeway CA. Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides. Proceedings of the National Academy of Sciences of the United States of America. 95: 10094-9. PMID 9707606 DOI: 10.1073/Pnas.95.17.10094 |
0.71 |
|
1998 |
Farr AG, Rudensky A. Medullary thymic epithelium: a mosaic of epithelial "self"? The Journal of Experimental Medicine. 188: 1-4. PMID 9653078 DOI: 10.1084/Jem.188.1.1 |
0.479 |
|
1998 |
Nakagawa T, Roth W, Wong P, Nelson A, Farr A, Deussing J, Villadangos JA, Ploegh H, Peters C, Rudensky AY. Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. Science (New York, N.Y.). 280: 450-3. PMID 9545226 DOI: 10.1126/Science.280.5362.450 |
0.718 |
|
1998 |
Liljedahl M, Winqvist O, Surh CD, Wong P, Ngo K, Teyton L, Peterson PA, Brunmark A, Rudensky AY, Fung-Leung WP, Karlsson L. Altered antigen presentation in mice lacking H2-O Immunity. 8: 233-243. PMID 9492004 DOI: 10.1016/S1074-7613(00)80475-6 |
0.634 |
|
1998 |
Kovats S, Grubin CE, Eastman S, deRoos P, Dongre A, Van Kaer L, Rudensky AY. Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo. The Journal of Experimental Medicine. 187: 245-51. PMID 9432982 DOI: 10.1084/Jem.187.2.245 |
0.421 |
|
1998 |
Grigg ME, McMahon CW, Morkowski S, Rudensky AY, Pullen AM. Mtv-1 Superantigen Trafficks Independently of Major Histocompatibility Complex Class II Directly to the B-Cell Surface by the Exocytic Pathway Journal of Virology. 72: 2577-2588. DOI: 10.1128/Jvi.72.4.2577-2588.1998 |
0.436 |
|
1997 |
La Flamme AC, Kahn SJ, Rudensky AY, Van Voorhis WC. Trypanosoma cruzi-infected macrophages are defective in major histocompatibility complex class II antigen presentation European Journal of Immunology. 27: 3085-3094. PMID 9464791 DOI: 10.1002/Eji.1830271202 |
0.507 |
|
1997 |
Kleijmeer MJ, Morkowski S, Griffith JM, Rudensky AY, Geuze HJ. Major histocompatibility complex class II compartments in human and mouse B lymphoblasts represent conventional endocytic compartments. The Journal of Cell Biology. 139: 639-49. PMID 9348281 DOI: 10.1083/Jcb.139.3.639 |
0.394 |
|
1997 |
Grubin CE, Kovats S, deRoos P, Rudensky AY. Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity. 7: 197-208. PMID 9285405 DOI: 10.1016/S1074-7613(00)80523-3 |
0.5 |
|
1997 |
Kovats S, Whiteley PE, Concannon P, Rudensky AY, Blum JS. Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines. European Journal of Immunology. 27: 1014-21. PMID 9130658 DOI: 10.1002/Eji.1830270431 |
0.503 |
|
1997 |
Morkowski S, Raposo G, Kleijimeer M, Geuze HJ, Rudensky AY. Assembly of an abundant endogenous major histocompatibility complex class II/peptide complex in class II compartments. European Journal of Immunology. 27: 609-17. PMID 9079799 DOI: 10.1002/Eji.1830270306 |
0.355 |
|
1997 |
Dongre A, DeRoos P, Yates JR, Rudensky A. Automated high through put analysis of peptides associated with MHC class II molecules Immunology Letters. 56: 190. DOI: 10.1016/S0165-2478(97)85762-8 |
0.319 |
|
1996 |
Farr A, DeRoos PC, Eastman S, Rudensky AY. Differential expression of CLIP:MHC class II and conventional endogenous peptide:MHC class II complexes by thymic epithelial cells and peripheral antigen-presenting cells. European Journal of Immunology. 26: 3185-93. PMID 8977321 DOI: 10.1002/Eji.1830261252 |
0.501 |
|
1996 |
Rudensky AY. Endogenous peptides associated with MHC class II and selection of CD4 T cells. Seminars in Immunology. 7: 399-409. PMID 8775465 DOI: 10.1006/Smim.1995.0044 |
0.54 |
|
1996 |
Wong P, Rudensky AY. Phenotype and function of CD4+ T cells in mice lacking invariant chain. Journal of Immunology (Baltimore, Md. : 1950). 156: 2133-42. PMID 8690902 |
0.679 |
|
1996 |
Eastman S, Deftos M, DeRoos PC, Hsu DH, Teyton L, Braunstein NS, Hackett CJ, Rudensky A. A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody. European Journal of Immunology. 26: 385-93. PMID 8617308 DOI: 10.1002/Eji.1830260218 |
0.377 |
|
1996 |
Smiley ST, Rudensky AY, Glimcher LH, Grusby MJ. Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. 93: 241-4. PMID 8552613 DOI: 10.1073/Pnas.93.1.241 |
0.408 |
|
1994 |
Humblet C, Rudensky AY, Kyewski B. Presentation and intercellular transfer of self antigen within the thymic microenvironment: expression of the Eα peptide-l-Ab complex by isolated thymic stromal cells International Immunology. 6: 1949-1958. PMID 7696212 DOI: 10.1093/Intimm/6.12.1949 |
0.422 |
|
1994 |
Rudensky AY, Maric M, Eastman S, Shoemaker L, DeRoos PC, Blum JS. Intracellular assembly and transport of endogenous peptide-MHC class II complexes. Immunity. 1: 585-94. PMID 7600287 DOI: 10.1016/1074-7613(94)90048-5 |
0.368 |
|
1993 |
Janeway CA, Mamula MJ, Rudensky AY. Rules for peptide presentation by MHC class II molecules International Reviews of Immunology. 10: 301-311. PMID 8294843 DOI: 10.3109/08830189309061705 |
0.552 |
|
1993 |
Rudensky A, Janeway CA. Studies on Naturally Processed Peptides Associated with MHC Class II Molecules Chemical Immunology. 57: 134-151. DOI: 10.1159/000319186 |
0.321 |
|
1992 |
Rath S, Lin RH, Rudensky A, Janeway CA. T and B cell receptors discriminate major histocompatibility complex class II conformations influenced by the invariant chain European Journal of Immunology. 22: 2121-2127. PMID 1379187 DOI: 10.1002/Eji.1830220824 |
0.602 |
|
1992 |
Rudensky AY, Preston-Hurlburt P, Al-Ramadi BK, Rothbard J, Janeway CA. Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs Nature. 359: 429-431. PMID 1328884 DOI: 10.1038/359429A0 |
0.562 |
|
1992 |
Janeway CA, Rudensky AY, Preston-Hurlburt P. Peptides bound to MHC Nature. 357: 120-120. DOI: 10.1038/357120B0 |
0.498 |
|
1992 |
Janeway C, Rudensky A, Rath S, Murphy D. It is easier for a camel to pass the needle's eye Current Biology. 2: 26-28. DOI: 10.1016/0960-9822(92)90419-B |
0.411 |
|
1991 |
Rudensky AY, Rath S, Preston-Hurlburt P, Murphy DB, Janeway CA. On the complexity of self Nature. 353: 660-662. PMID 1656278 DOI: 10.1038/353660A0 |
0.591 |
|
1990 |
Rudensky AY, Mazel SM, Blechman JM, Yurin VL. Immunoglobulin-specific T-B cell interaction. IV. B cell presentation of idiotypic determinant(s) of monoclonal anti-surface immunoglobulin antibody to idiotope-recognizing helper T clones. European Journal of Immunology. 20: 1691-6. PMID 2120062 DOI: 10.1002/Eji.1830200811 |
0.499 |
|
1990 |
Mazel SM, Rudensky AY, Yurin VL. Immunoglobulin-specific T-B cell interaction. III. B cell activation by immunoglobulin-recognizing T cell clones. European Journal of Immunology. 20: 833-9. PMID 2112093 DOI: 10.1002/Eji.1830200418 |
0.46 |
|
1990 |
Rudensky AY, Mazel SM, Yurin VL. Presentation of endogenous immunoglobulin determinant to immunoglobulin-recognizing T cell clones by the thymic cells. European Journal of Immunology. 20: 2235-9. PMID 1700750 DOI: 10.1002/Eji.1830201012 |
0.537 |
|
1989 |
Yurin VL, Rudensky AY, Mazel SM, Blechman JM. Immunoglobulin-specific T-B cell interaction. II. T cell clones recognize the processed form of B cells' own surface immunoglobulin in the context of the major histocompatibility complex class II molecule. European Journal of Immunology. 19: 1685-91. PMID 2507327 DOI: 10.1002/eji.1830190924 |
0.368 |
|
1989 |
Rudensky AY, Yurin VL. Immunoglobulin-specific T-B cell interaction. I. Presentation of self immunoglobulin determinants by B lymphocytes. European Journal of Immunology. 19: 1677-83. PMID 2477255 DOI: 10.1002/Eji.1830190923 |
0.388 |
|
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