Alexander Y. Rudensky - Related publications

University of Washington, Seattle, Seattle, WA 
Immunology, Microbiology Biology, Virology Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Klarquist J, Cross EW, Thompson SB, Willett B, Aldridge DL, Caffrey-Carr AK, Xu Z, Hunter CA, Getahun A, Kedl RM. B cells promote CD8 T cell primary and memory responses to subunit vaccines. Cell Reports. 36: 109591. PMID 34433030 DOI: 10.1016/j.celrep.2021.109591   
2021 Xu H, Jia J. Single-Cell RNA Sequencing of Peripheral Blood Reveals Immune Cell Signatures in Alzheimer's Disease. Frontiers in Immunology. 12: 645666. PMID 34447367 DOI: 10.3389/fimmu.2021.645666   
2021 Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, et al. An engineered IL-2 partial agonist promotes CD8 T cell stemness. Nature. PMID 34526724 DOI: 10.1038/s41586-021-03861-0   
2021 Palma AM, Hanes MR, Marshall JS. Mast Cell Modulation of B Cell Responses: An Under-Appreciated Partnership in Host Defence. Frontiers in Immunology. 12: 718499. PMID 34566974 DOI: 10.3389/fimmu.2021.718499   
2021 Wang Z, Xie L, Ding G, Song S, Chen L, Li G, Xia M, Han D, Zheng Y, Liu J, Xiao T, Zhang H, Huang Y, Li Y, Huang M. Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients. Nature Communications. 12: 5444. PMID 34521850 DOI: 10.1038/s41467-021-25771-5   
2021 Li Y, Li J, Yuan Q, Bian X, Long F, Duan R, Gao F, Gao S, Wei S, Wang A, Liu A, Li X, Sun W, Liu Q. Deficiency in WDFY4 reduces the number of CD8 T cells via reactive oxygen species-induced apoptosis. Molecular Immunology. 139: 131-138. PMID 34482201 DOI: 10.1016/j.molimm.2021.08.022   
2021 Jin W, Yang Q, Peng Y, Yan C, Li Y, Luo Z, Xiao B, Xu L, Yang H. Single-cell RNA-Seq reveals transcriptional heterogeneity and immune subtypes associated with disease activity in human myasthenia gravis. Cell Discovery. 7: 85. PMID 34521820 DOI: 10.1038/s41421-021-00314-w   
2021 Fujiwara Y, Torphy RJ, Sun Y, Miller EN, Ho F, Borcherding N, Wu T, Torres RM, Zhang W, Schulick RD, Zhu Y. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. Nature Communications. 12: 5857. PMID 34615877 DOI: 10.1038/s41467-021-26135-9   
2021 Liu J, Yin W, Westerberg LS, Lee P, Gong Q, Chen Y, Dong L, Liu C. Immune Dysregulation in IgG-Related Disease. Frontiers in Immunology. 12: 738540. PMID 34539675 DOI: 10.3389/fimmu.2021.738540   
2021 Zhang X, Ge R, Chen H, Ahiafor M, Liu B, Chen J, Fan X. Follicular Helper CD4 T Cells, Follicular Regulatory CD4 T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. Mediators of Inflammation. 2021: 2058964. PMID 34552387 DOI: 10.1155/2021/2058964   
2021 Kretschmer L, Busch DH, Buchholz VR. A Single-Cell Perspective on Memory T-Cell Differentiation. Cold Spring Harbor Perspectives in Biology. 13. PMID 33903160 DOI: 10.1101/cshperspect.a038067   
2021 Cho S, Dong J, Lu LF. Cell-intrinsic and -extrinsic roles of miRNAs in regulating T cell immunity. Immunological Reviews. PMID 34549446 DOI: 10.1111/imr.13029   
2021 Kok L, Masopust D, Schumacher TN. The precursors of CD8 tissue resident memory T cells: from lymphoid organs to infected tissues. Nature Reviews. Immunology. PMID 34480118 DOI: 10.1038/s41577-021-00590-3   
2021 Lu YJ, Barreira-Silva P, Boyce S, Powers J, Cavallo K, Behar SM. CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection. Cell Reports. 36: 109696. PMID 34525366 DOI: 10.1016/j.celrep.2021.109696   
2021 Figueroa MG, Parker LM, Krol K, Zhao M. Distal Promoter-Driven Cre Shows Cell Type-Specific Function in Innate-like T Cells. Immunohorizons. 5: 772-781. PMID 34583938 DOI: 10.4049/immunohorizons.2100079   
2021 Lévy R, Langlais D, Béziat V, Rapaport F, Rao G, Lazarov T, Bourgey M, Zhou YJ, Briand C, Moriya K, Ailal F, Avery DT, Markle J, Lim AI, Ogishi M, et al. Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents. The Journal of Clinical Investigation. 131. PMID 34623332 DOI: 10.1172/JCI150143   
2021 Wang B, Wang Y, Sun X, Deng G, Huang W, Wu X, Gu Y, Tian Z, Fan Z, Xu Q, Chen H, Sun Y. CXCR6 is required for antitumor efficacy of intratumoral CD8 T cell. Journal For Immunotherapy of Cancer. 9. PMID 34462326 DOI: 10.1136/jitc-2021-003100   
2021 Gaudette BT, Roman CJ, Ochoa TA, Gómez Atria D, Jones DD, Siebel CW, Maillard I, Allman D. Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation. The Journal of Clinical Investigation. PMID 34473651 DOI: 10.1172/JCI151975   
2021 Hu W, Wang ZM, Feng Y, Schizas M, Hoyos BE, van der Veeken J, Verter JG, Bou-Puerto R, Rudensky AY. Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity. Nature Immunology. PMID 34426690 DOI: 10.1038/s41590-021-01001-4   
2021 Elmentaite R, Kumasaka N, Roberts K, Fleming A, Dann E, King HW, Kleshchevnikov V, Dabrowska M, Pritchard S, Bolt L, Vieira SF, Mamanova L, Huang N, Perrone F, Goh Kai'En I, et al. Cells of the human intestinal tract mapped across space and time. Nature. 597: 250-255. PMID 34497389 DOI: 10.1038/s41586-021-03852-1   
2021 Ciecko AE, Schauder DM, Foda B, Petrova G, Kasmani MY, Burns R, Lin CW, Drobyski WR, Cui W, Chen YG. Self-Renewing Islet TCF1 CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1 Terminal Effectors during the Progression of Type 1 Diabetes. Journal of Immunology (Baltimore, Md. : 1950). PMID 34507949 DOI: 10.4049/jimmunol.2100362   
2021 Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N. Ddb1 Is Essential for the Expansion of CD4 Helper T Cells by Regulating Cell Cycle Progression and Cell Death. Frontiers in Immunology. 12: 722273. PMID 34526995 DOI: 10.3389/fimmu.2021.722273   
2021 Cimen Bozkus C, Blazquez AB, Enokida T, Bhardwaj N. A T-cell-based immunogenicity protocol for evaluating human antigen-specific responses. Star Protocols. 2: 100758. PMID 34458873 DOI: 10.1016/j.xpro.2021.100758   
2021 Wong HS, Germain RN. Mesoscale T cell antigen discrimination emerges from intercellular feedback. Trends in Immunology. PMID 34493455 DOI: 10.1016/   
2021 Shenoy AT, Lyon De Ana C, Arafa EI, Salwig I, Barker KA, Korkmaz FT, Ramanujan A, Etesami NS, Soucy AM, Martin IMC, Tilton BR, Hinds A, Goltry WN, Kathuria H, Braun T, et al. Antigen presentation by lung epithelial cells directs CD4 T cell function and regulates barrier immunity. Nature Communications. 12: 5834. PMID 34611166 DOI: 10.1038/s41467-021-26045-w   
2021 Jacquelot N, Seillet C, Souza-Fonseca-Guimaraes F, Sacher AG, Belz GT, Ohashi PS. Natural Killer Cells and Type 1 Innate Lymphoid Cells in Hepatocellular Carcinoma: Current Knowledge and Future Perspectives. International Journal of Molecular Sciences. 22. PMID 34445750 DOI: 10.3390/ijms22169044   
2021 Li H, Gao Y, Xie L, Wang R, Duan R, Li Z, Chen B, Zhu L, Wang X, Su W. Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease. Frontiers in Immunology. 12: 739605. PMID 34484247 DOI: 10.3389/fimmu.2021.739605   
2021 Simon S, Bugos G, Salter AI, Riddell SR. Synthetic receptors for logic gated T cell recognition and function. Current Opinion in Immunology. 74: 9-17. PMID 34571290 DOI: 10.1016/j.coi.2021.09.003   
2021 Cordero H, King RG, Dogra P, Dufeu C, See SB, Chong AM, Uhlemann AC, Ho SH, Kalfa DM, Bacha EA, Kearney JF, Zorn E. Intrathymic differentiation of natural antibody-producing plasma cells in human neonates. Nature Communications. 12: 5761. PMID 34599177 DOI: 10.1038/s41467-021-26069-2   
2021 Tong Y, Cheng LQ, Li X, Yu XP, Shu RH, Zhang JH, Meng Q, Qin QL, Tang K, Xu JX, Zhang H. Establishment of an immortalized cell line derived from the pupal ovary of Mythimna separata (Lepidoptera: Noctuidae) and identification of the cell source. Cell and Tissue Research. PMID 34599689 DOI: 10.1007/s00441-021-03528-2   
2021 Chin DS, Lim CSY, Nordin F, Arifin N, Jun TG. Antibody-dependent cell-mediated cytotoxicity through Natural Killer (NK) cells: unlocking NK cells for future immunotherapy. Current Pharmaceutical Biotechnology. PMID 34414871 DOI: 10.2174/1389201022666210820093608   
2021 Finney J, Kelsoe G. Continuous Culture of Mouse Primary B Lymphocytes by Forced Expression of . Journal of Immunology (Baltimore, Md. : 1950). 207: 1478-1492. PMID 34389622 DOI: 10.4049/jimmunol.2100172   
2021 Chao JL, Korzinkin M, Zhavoronkov A, Ozerov IV, Walker MT, Higgins K, Lingen MW, Izumchenko E, Savage PA. Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma. Cell Reports. Medicine. 2: 100399. PMID 34622236 DOI: 10.1016/j.xcrm.2021.100399   
2021 Mo LH, Han HY, Jin QR, Song YN, Wu GH, Zhang Y, Yang LT, Liu T, Liu ZG, Feng Y, Yang PC. T cell activator-carrying extracellular vesicles induce antigen specific regulatory T cells. Clinical and Experimental Immunology. PMID 34418066 DOI: 10.1111/cei.13655   
2021 Li Y, Harunori O, Fu S, Xing F, Wu H, Wang J, Chen A, Ren X, Peng D, Ling X, Shi M, Wu H. Immune normalization strategy against suboptimal health status: safe and efficacious therapy using mixed-natural killer cells. Aging. 13. PMID 34461606 DOI: 10.18632/aging.203279   
2021 Naqvi RA, Datta M, Khan SH, Naqvi AR. Regulatory roles of MicroRNA in shaping T cell function, differentiation and polarization. Seminars in Cell & Developmental Biology. PMID 34446356 DOI: 10.1016/j.semcdb.2021.08.003   
2021 Morrison WI, Aguado A, Sheldrake TA, Palmateer NC, Ifeonu OO, Tretina K, Parsons K, Fenoy E, Connelley T, Nielsen M, Silva JC. CD4 T Cell Responses to in Immune Cattle Recognize a Diverse Set of Parasite Antigens Presented on the Surface of Infected Lymphoblasts. Journal of Immunology (Baltimore, Md. : 1950). PMID 34507950 DOI: 10.4049/jimmunol.2100331   
2021 Janelle V, Neault M, Lebel MÈ, De Sousa DM, Boulet S, Durrieu L, Carli C, Muzac C, Lemieux S, Labrecque N, Melichar HJ, Mallette FA, Delisle JS. p16 Regulates Cellular Senescence in PD-1-Expressing Human T Cells. Frontiers in Immunology. 12: 698565. PMID 34434190 DOI: 10.3389/fimmu.2021.698565   
2021 Wu J, Chen Z, Wickström SL, Gao J, He X, Jing X, Wu J, Du Q, Yang M, Chen Y, Zhang D, Yin X, Guo Z, Jensen L, Yang Y, et al. Interleukin-33 is a Novel Immunosuppressor that Protects Cancer Cells from TIL Killing by a Macrophage-Mediated Shedding Mechanism. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2101029. PMID 34486239 DOI: 10.1002/advs.202101029   
2021 Kumar V. Toll-Like Receptors in Adaptive Immunity. Handbook of Experimental Pharmacology. PMID 34510306 DOI: 10.1007/164_2021_543   
2021 Holthaus L, Sharma V, Brandt D, Ziegler AG, Jastroch M, Bonifacio E. Functional and metabolic fitness of human CD4 T lymphocytes during metabolic stress. Life Science Alliance. 4. PMID 34580176 DOI: 10.26508/lsa.202101013   
2021 Peng Z, Zhang Y, Ma X, Zhou M, Wu S, Song Z, Yuan Y, Chen Y, Li Y, Wang G, Huang F, Qiao Y, Xia B, Liu W, Liu J, et al. Brd4 Regulates the Homeostasis of CD8 T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation. Frontiers in Immunology. 12: 728082. PMID 34512660 DOI: 10.3389/fimmu.2021.728082   
2021 Riss TL, Moravec RA, Duellman SJ, Niles AL. Treating Cells as Reagents to Design Reproducible Assays. Slas Discovery : Advancing Life Sciences R & D. 24725552211039754. PMID 34530643 DOI: 10.1177/24725552211039754   
2021 Zhang J, Wang H, Wu H, Qiang G. The Functionalities and Clinical Significance of Tumor-Infiltrating Immune Cells in Esophageal Squamous Cell Carcinoma. Biomed Research International. 2021: 8635381. PMID 34616847 DOI: 10.1155/2021/8635381   
2021 Landin AM, Cox C, Yu B, Bejanyan N, Davila M, Kelley L. Expansion and Enrichment of Gamma-Delta (γδ) T Cells from Apheresed Human Product. Journal of Visualized Experiments : Jove. PMID 34633380 DOI: 10.3791/62622   
2021 Jacobse J, Li J, Rings EHHM, Samsom JN, Goettel JA. Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease. Frontiers in Immunology. 12: 716499. PMID 34421921 DOI: 10.3389/fimmu.2021.716499   
2021 Wu J, Tang L, Ma Y, Li Y, Zhang D, Li Q, Mei H, Hu Y. Immunological Profiling of COVID-19 Patients with Pulmonary Sequelae. Mbio. e0159921. PMID 34488453 DOI: 10.1128/mBio.01599-21   
2021 Wang S, Pisco AO, McGeever A, Brbic M, Zitnik M, Darmanis S, Leskovec J, Karkanias J, Altman RB. Leveraging the Cell Ontology to classify unseen cell types. Nature Communications. 12: 5556. PMID 34548483 DOI: 10.1038/s41467-021-25725-x   
2021 Shen M, Child T, Mittal M, Sarodey G, Salim R, Granne I, Southcombe JH. B Cell Subset Analysis and Gene Expression Characterization in Mid-Luteal Endometrium. Frontiers in Cell and Developmental Biology. 9: 709280. PMID 34447753 DOI: 10.3389/fcell.2021.709280   
2021 Rahimi N, Ho RXY, Chandler KB, De La Cena KOC, Amraei R, Mitchel AJ, Engblom N, Costello CE. The cell adhesion molecule TMIGD1 binds to moesin and regulates tubulin acetylation and cell migration. Journal of Biomedical Science. 28: 61. PMID 34503512 DOI: 10.1186/s12929-021-00757-z