Jack Hutcheson, Ph.D. - Publications

2008 Saint Louis University, St. Louis, MO, United States 
Cell Biology

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Tsai F, Homan PJ, Agrawal H, Misharin AV, Abdala-Valencia H, Haines GK, Dominguez S, Bloomfield CL, Saber R, Chang A, Mohan C, Hutcheson J, Davidson A, Budinger GRS, Bouillet P, et al. Bim suppresses the development of SLE by limiting myeloid inflammatory responses. The Journal of Experimental Medicine. PMID 29114065 DOI: 10.1084/jem.20170479  0.56
2016 Orme JJ, Du Y, Vanarsa K, Mayeux J, Li L, Mutwally A, Arriens C, Min S, Hutcheson J, Davis LS, Chong BF, Satterthwaite AB, Wu T, Mohan C. Heightened Cleavage of Axl Receptor Tyrosine Kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE. Clinical Immunology (Orlando, Fla.). PMID 27237127 DOI: 10.1016/j.clim.2016.05.011  0.56
2015 Cuda CM, Misharin AV, Khare S, Saber R, Tsai F, Archer AM, Homan PJ, Haines GK, Hutcheson J, Dorfleutner A, Budinger GR, Stehlik C, Perlman H. Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner. Arthritis Research & Therapy. 17: 291. PMID 26471282 DOI: 10.1186/s13075-015-0794-z  0.56
2015 Hutcheson J. Adipokines influence the inflammatory balance in autoimmunity. Cytokine. 75: 272-9. PMID 26044595 DOI: 10.1016/j.cyto.2015.04.004  0.56
2015 Hutcheson J, Witkiewicz AK, Knudsen ES. The RB tumor suppressor at the intersection of proliferation and immunity: relevance to disease immune evasion and immunotherapy. Cell Cycle (Georgetown, Tex.). 14: 3812-9. PMID 25714546 DOI: 10.1080/15384101.2015.1010922  0.56
2014 Cuda CM, Misharin AV, Gierut AK, Saber R, Haines GK, Hutcheson J, Hedrick SM, Mohan C, Budinger GS, Stehlik C, Perlman H. Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. Journal of Immunology (Baltimore, Md. : 1950). 192: 5548-60. PMID 24808358 DOI: 10.4049/jimmunol.1400122  0.56
2014 Reed C, Hutcheson J, Mayhew CN, Witkiewicz AK, Knudsen ES. RB tumor suppressive function in response to xenobiotic hepatocarcinogens. The American Journal of Pathology. 184: 1853-9. PMID 24726645 DOI: 10.1016/j.ajpath.2014.02.025  0.56
2012 Hutcheson J, Vanarsa K, Bashmakov A, Grewal S, Sajitharan D, Chang BY, Buggy JJ, Zhou XJ, Du Y, Satterthwaite AB, Mohan C. Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus. Arthritis Research & Therapy. 14: R243. PMID 23136880 DOI: 10.1186/ar4086  0.44
2012 Min SY, Fu Y, Hutcheson J, Wu T, Khobahy E, Zhu J, Vanarsa K, Du Y, Park MJ, Park HS, Saxena R, Kim HY, Mohan C. Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway. Clinical Immunology (Orlando, Fla.). 143: 59-72. PMID 22341910 DOI: 10.1016/j.clim.2012.01.003  0.56
2012 Cuda CM, Agrawal H, Misharin AV, Haines GK, Hutcheson J, Weber E, Schoenfeldt JA, Mohan C, Pope RM, Perlman H. Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice. Arthritis and Rheumatism. 64: 808-20. PMID 22143975 DOI: 10.1002/art.34317  0.56
2011 Peng A, Wu T, Zeng C, Rakheja D, Zhu J, Ye T, Hutcheson J, Vaziri ND, Liu Z, Mohan C, Zhou XJ. Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability. Plos One. 6: e23268. PMID 21858050 DOI: 10.1371/journal.pone.0023268  0.44
2011 Davis LS, Hutcheson J, Mohan C. The role of cytokines in the pathogenesis and treatment of systemic lupus erythematosus. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 781-9. PMID 21787222 DOI: 10.1089/jir.2011.0047  0.56
2010 Scatizzi JC, Hutcheson J, Pope RM, Firestein GS, Koch AE, Mavers M, Smason A, Agrawal H, Haines GK, Chandel NS, Hotchkiss RS, Perlman H. Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. Arthritis and Rheumatism. 62: 441-51. PMID 20112357 DOI: 10.1002/art.27198  0.56
2009 Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. European Journal of Immunology. 39: 820-5. PMID 19189309 DOI: 10.1002/eji.200838683  0.56
2008 Hutcheson J, Perlman H. BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention. Oncogene. 27: S168-75. PMID 19641502 DOI: 10.1038/onc.2009.54  0.56
2008 Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK, Wu T, Li QZ, Davis LS, Mohan C, Perlman H. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity. 28: 206-17. PMID 18275831 DOI: 10.1016/j.immuni.2007.12.015  0.56
2007 Hutcheson J, Perlman H. Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes. Immunobiology. 212: 629-36. PMID 17869640 DOI: 10.1016/j.imbio.2007.05.003  0.56
2007 Scatizzi JC, Hutcheson J, Bickel E, Haines GK, Perlman H. Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis. Arthritis Research & Therapy. 9: R49. PMID 17509138 DOI: 10.1186/ar2204  0.56
2006 Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis. Arthritis and Rheumatism. 54: 3182-93. PMID 17009248 DOI: 10.1002/art.22133  0.56
2006 Scatizzi JC, Hutcheson J, Bickel E, Woods JM, Klosowska K, Moore TL, Haines GK, Perlman H. p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis. The American Journal of Pathology. 168: 1531-41. PMID 16651620 DOI: 10.2353/ajpath.2006.050555  0.56
2005 Hutcheson J, Scatizzi JC, Bickel E, Brown NJ, Bouillet P, Strasser A, Perlman H. Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis. The Journal of Experimental Medicine. 201: 1949-60. PMID 15967824 DOI: 10.1084/jem.20041484  0.56
2004 Brown NJ, Hutcheson J, Bickel E, Scatizzi JC, Albee LD, Haines GK, Eslick J, Bradley K, Taricone E, Perlman H. Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 7584-93. PMID 15585886  0.56
2004 Yang J, Sato K, Aprahamian T, Brown NJ, Hutcheson J, Bialik A, Perlman H, Walsh K. Endothelial overexpression of Fas ligand decreases atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1466-73. PMID 15178561 DOI: 10.1161/01.ATV.0000134402.94963.2f  0.56
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