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Hyunyoung Jeong, Ph.D. - Publications

Affiliations: 
2004 University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Pharmacy, Pharmacology
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Guo Y, Lee H, Jeong H. Gut microbiota in reductive drug metabolism. Progress in Molecular Biology and Translational Science. 171: 61-93. PMID 32475528 DOI: 10.1016/Bs.Pmbts.2020.04.002  0.347
2020 Jeong H, Stika CS. Methods to study mechanisms underlying altered hepatic drug elimination during pregnancy. Seminars in Perinatology. 151228. PMID 32122644 DOI: 10.1016/J.Semperi.2020.151228  0.35
2019 Zhong G, Kirkwood J, Won KJ, Tjota N, Jeong HY, Isoherranen N. Characterization of Vitamin A Metabolome in Human Livers with and without NAFLD. The Journal of Pharmacology and Experimental Therapeutics. PMID 31043436 DOI: 10.1124/Jpet.119.258517  0.325
2019 Won KJ, Park JS, Jeong H. Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid. Journal of Lipid Research. PMID 30709899 DOI: 10.1194/Jlr.M088880  0.327
2018 Guo Y, Crnkovic CM, Won KJ, Yang X, Lee JR, Orjala J, Lee H, Jeong H. Commensal gut bacteria convert the immunosuppressant tacrolimus to less potent metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30598508 DOI: 10.1124/Dmd.118.084772  0.344
2018 Jeong H, Kim S, Kim MY, Lee J, An BH, Kim HD, Jeong H, Song YS, Chang M. Inhibitory and Inductive Effects of Extract and Its Flavonoid Constituents on Cytochrome P450s and UDP-Glucuronosyltransferases. International Journal of Molecular Sciences. 19. PMID 30380747 DOI: 10.3390/Ijms19113400  0.446
2018 Morgan ET, Dempsey JL, Mimche SM, Lamb TJ, Kulkarni S, Cui JY, Jeong H, Slitt AL. Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29514828 DOI: 10.1124/Dmd.117.079905  0.372
2018 Yeo WS, Arya R, Kim KK, Jeong H, Cho KH, Bae T. The FDA-approved anti-cancer drugs, streptozotocin and floxuridine, reduce the virulence of Staphylococcus aureus. Scientific Reports. 8: 2521. PMID 29410445 DOI: 10.1038/S41598-018-20617-5  0.312
2018 Ning M, Duarte JD, Rubin LH, Jeong H. CYP2D6 protein level is the major contributor to inter-individual variability in CYP2D6-mediated drug metabolism in healthy human liver tissue. Clinical Pharmacology and Therapeutics. PMID 29349771 DOI: 10.1002/Cpt.1032  0.341
2017 Nobutani K, Miyoshi J, Musch MW, Nishiyama M, Watanabe J, Kaneko A, Yamamoto M, Yoshida M, Kono T, Jeong H, Chang EB. Daikenchuto (TU-100) alters murine hepatic and intestinal drug metabolizing enzymes in an in vivo dietary model: effects of gender and withdrawal. Pharmacology Research & Perspectives. 5. PMID 28971602 DOI: 10.1002/Prp2.361  0.388
2017 Cho S, Tripathi A, Chlipala G, Green S, Lee H, Chang EB, Jeong H. Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice. Plos One. 12: e0182977. PMID 28832650 DOI: 10.1371/Journal.Pone.0182977  0.308
2017 Ning M, Jeong H. High Fat Diet Feeding Alters Expression of Hepatic Drug-metabolizing Enzymes in Mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28442500 DOI: 10.1124/Dmd.117.075655  0.321
2017 Kent R, Jeong H. Effects of fenofibrate on the expression of small heterodimer partner (SHP) and cytochrome P450 (CYP) 2D6. Drug Metabolism Letters. PMID 28403802 DOI: 10.2174/1872312811666170407164631  0.328
2017 Yu AM, Ingelman-Sundberg M, Cherrington NJ, Aleksunes LM, Zanger UM, Xie W, Jeong H, Morgan EM, Turnbaugh PJ, Klaassen CD, Bhatt AP, Redinbo MR, Hao P, Waxman DJ, Wang L, et al. Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21(st) International Symposium on Microsomes and Drug Oxidations (MDO). Acta Pharmaceutica Sinica. B. 7: 241-248. PMID 28388695 DOI: 10.1016/J.Apsb.2016.12.006  0.362
2017 Jeong H. CYP2D6-humanized mice as a model to study altered drug metabolism during pregnancy Drug Metabolism and Pharmacokinetics. 32. DOI: 10.1016/J.Dmpk.2016.10.035  0.353
2016 Cho SJ, Ning M, Zhang Y, Rubin LH, Jeong H. 17β-Estradiol up-regulates UDP-glucuronosyltransferase 1A9 expression via estrogen receptor α. Acta Pharmaceutica Sinica. B. 6: 504-509. PMID 27709019 DOI: 10.1016/J.Apsb.2016.04.005  0.334
2016 Pan X, Ning M, Jeong H. Transcriptional regulation of CYP2D6 expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27698228 DOI: 10.1124/Dmd.116.072249  0.354
2015 Tracy TS, Chaudhry AS, Prasad B, Thummel KE, Schuetz EG, Zhong XB, Tien YC, Jeong H, Pan X, Shireman LM, Tay-Sontheimer J, Lin YS. Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26681736 DOI: 10.1124/Dmd.115.067900  0.39
2015 Zhang N, Liu Y, Jeong H. Drug-Drug Interaction Potentials of Tyrosine Kinase Inhibitors via Inhibition of UDP-Glucuronosyltransferases. Scientific Reports. 5: 17778. PMID 26642944 DOI: 10.1038/Srep17778  0.306
2015 Ao L, Reichel DA, Hu D, Jeong H, Kim KB, Bae Y, Lee W. Polymer Micelle Formulations of Proteasome Inhibitor Carfilzomib for Improved Metabolic Stability and Anti-Cancer Efficacy in Human Multiple Myeloma and Lung Cancer Cell Lines. The Journal of Pharmacology and Experimental Therapeutics. PMID 26311812 DOI: 10.1124/Jpet.115.226993  0.338
2015 Pan X, Jeong H. Estrogen-Induced Cholestasis Leads to Repressed CYP2D6 Expression in CYP2D6-Humanized Mice. Molecular Pharmacology. 88: 106-12. PMID 25943116 DOI: 10.1124/Mol.115.098822  0.323
2015 Pan X, Lee YK, Jeong H. Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1002-7. PMID 25926433 DOI: 10.1124/Dmd.115.064758  0.384
2015 Zhang S, Pan X, Jeong H. GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 743-8. PMID 25725071 DOI: 10.1124/Dmd.114.062836  0.361
2014 Koh KH, Pan X, Zhang W, McLachlan A, Urrutia R, Jeong H. Krüppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice. Molecular Pharmacology. 86: 727-35. PMID 25217496 DOI: 10.1124/Mol.114.093666  0.333
2014 Lee JK, Chung HJ, Fischer L, Fischer J, Gonzalez FJ, Jeong H. Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 492-9. PMID 24408518 DOI: 10.1124/Dmd.113.055384  0.351
2014 Koh KH, Pan X, Shen HW, Arnold SL, Yu AM, Gonzalez FJ, Isoherranen N, Jeong H. Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice. The Journal of Biological Chemistry. 289: 3105-13. PMID 24318876 DOI: 10.1074/Jbc.M113.526798  0.333
2013 Zhang N, Seguin RP, Kunze KL, Zhang YY, Jeong H. Characterization of inhibition kinetics of (S)-warfarin hydroxylation by noscapine: implications in warfarin therapy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 2114-23. PMID 24046330 DOI: 10.1124/Dmd.113.053330  0.35
2013 Choi SY, Koh KH, Jeong H. Isoform-specific regulation of cytochromes P450 expression by estradiol and progesterone. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 263-9. PMID 22837389 DOI: 10.1124/Dmd.112.046276  0.368
2012 Vaynshteyn D, Jeong H. Caffeine induces CYP1A2 expression in rat hepatocytes but not in human hepatocytes. Drug Metabolism Letters. 6: 116-9. PMID 23167901 DOI: 10.2174/187231212804096745  0.425
2012 Koh KH, Jurkovic S, Yang K, Choi SY, Jung JW, Kim KP, Zhang W, Jeong H. Estradiol induces cytochrome P450 2B6 expression at high concentrations: implication in estrogen-mediated gene regulation in pregnancy. Biochemical Pharmacology. 84: 93-103. PMID 22484313 DOI: 10.1016/J.Bcp.2012.03.016  0.319
2011 Cavallari LH, Jeong H, Bress A. Role of cytochrome P450 genotype in the steps toward personalized drug therapy. Pharmacogenomics and Personalized Medicine. 4: 123-36. PMID 23226058 DOI: 10.2147/Pgpm.S15497  0.351
2011 Choi SY, Fischer L, Yang K, Chung H, Jeong H. Isoform-specific regulation of cytochrome P450 expression and activity by estradiol in female rats. Biochemical Pharmacology. 81: 777-82. PMID 21219883 DOI: 10.1016/J.Bcp.2010.12.019  0.387
2011 Koh KH, Xie H, Yu AM, Jeong H. Altered cytochrome P450 expression in mice during pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 165-9. PMID 20971892 DOI: 10.1124/Dmd.110.035790  0.345
2010 Della Torre M, Hibbard JU, Jeong H, Fischer JH. Betamethasone in pregnancy: influence of maternal body weight and multiple gestation on pharmacokinetics. American Journal of Obstetrics and Gynecology. 203: 254.e1-12. PMID 20816148 DOI: 10.1016/J.Ajog.2010.06.029  0.304
2010 Yang K, Koh KH, Jeong H. Induction of CYP2B6 and CYP3A4 expression by 1-aminobenzotriazole (ABT) in human hepatocytes. Drug Metabolism Letters. 4: 129-33. PMID 20642445 DOI: 10.2174/187231210791698410  0.391
2010 Jeong H. Altered drug metabolism during pregnancy: hormonal regulation of drug-metabolizing enzymes. Expert Opinion On Drug Metabolism & Toxicology. 6: 689-99. PMID 20367533 DOI: 10.1517/17425251003677755  0.313
2009 Choi S, Sainz B, Corcoran P, Uprichard S, Jeong H. Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells Xenobiotica. 39: 205-217. PMID 19280519 DOI: 10.1080/00498250802613620  0.345
2008 Jeong H, Choi S, Song JW, Chen H, Fischer JH. Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 38: 62-75. PMID 18098064 DOI: 10.1080/00498250701744633  0.315
2006 Jeong H, Chiou WL. Role of P-glycoprotein in the hepatic metabolism of tacrolimus. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 36: 1-13. PMID 16507509 DOI: 10.1080/00498250500485115  0.585
2003 Chiou WL, Ma C, Wu TC, Jeong HY. Unexpected lack of effect of the rifampin-induced P-glycoprotein on the oral bioavailability of its substrate, talinolol, in humans: implication in phenotyping. Journal of Pharmaceutical Sciences. 92: 4-7; discussion 8-9. PMID 12486675 DOI: 10.1002/Jps.10261  0.737
2002 Wu TC, Ma C, Jeong H, Yao HM, Chiou WL. Comparison of gastrointestinal absorption between human and rat: the role of intestinal absorptive surface area and unstirred aqueous layer(1). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 40: 1901-2; author reply. PMID 12419705 DOI: 10.1016/S0278-6915(02)00233-8  0.711
2002 Wu TC, Ma C, Jeong H, Yao HM, Chiou WL. Comparison of gastrointestinal absorption between human and rat: the role of intestinal absorptive surface area and unstirred aqueous layer. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 40: 1727-8. PMID 12176100 DOI: 10.1016/S0278-6915(02)00112-6  0.711
2002 Chiou WL, Wu TC, Ma C, Jeong HY. Enhanced oral bioavailability of docetaxel by coadministration of cyclosporine: quantitation and role of P-glycoprotein. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 1951-2; author reply. PMID 11919259 DOI: 10.1200/Jco.2002.20.7.1951  0.736
2001 Chiou WL, Jeong HY, Wu TC, Ma C. Use of the erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization. Clinical Pharmacology and Therapeutics. 70: 305-10. PMID 11673745 DOI: 10.1016/S0009-9236(01)45600-1  0.692
2000 Chiou WL, Ma C, Chung SM, Wu TC, Jeong HY. Similarity in the linear and non-linear oral absorption of drugs between human and rat. International Journal of Clinical Pharmacology and Therapeutics. 38: 532-9. PMID 11097145 DOI: 10.5414/CPP38532  0.73
2000 Chiou WL, Jeong HY, Chung SM, Wu TC. Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans. Pharmaceutical Research. 17: 135-40. PMID 10751026 DOI: 10.1023/A:1007552927404  0.755
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