John D. Gearhart - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology, Molecular Biology, Neuroscience Biology
Website:
https://hss.sas.upenn.edu/people/john-d-gearhart

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Graham CF, Solter D, Gearhart JD, Nadeau JH, Knowles BB. Honoring the work and life of Leroy C. Stevens. A symposium as part of the International Stem Cell Initiative Workshop. The International Journal of Developmental Biology. 60: 327-336. PMID 28000904 DOI: 10.1387/Ijdb.160420Bk  0.495
2015 Bazley FA, Liu CF, Yuan X, Hao H, All AH, De Los Angeles A, Zambidis ET, Gearhart J, Kerr C. Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells. Stem Cells and Development. PMID 26154167 DOI: 10.1089/Scd.2015.0100  0.507
2015 All AH, Gharibani P, Gupta S, Bazley FA, Pashai N, Chou BK, Shah S, Resar LM, Cheng L, Gearhart JD, Kerr CL. Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. Plos One. 10: e0116933. PMID 25635918 DOI: 10.1371/Journal.Pone.0116933  0.451
2015 All AH, Gharibani P, Gupta S, Bazley FA, Pashai N, Chou B, Shah S, Resar LM, Cheng L, Gearhart JD, Kerr CL. Bright field microscopy images of the various stages of oligodendrocyte differentiation from induced pluripotent stem cells of the BC1 line. Plos One. DOI: 10.1371/Journal.Pone.0116933.G001  0.404
2014 Ifkovits JL, Addis RC, Epstein JA, Gearhart JD. Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes. Plos One. 9: e89678. PMID 24586958 DOI: 10.1371/Journal.Pone.0089678  0.388
2014 Stasi K, Goings D, Huang J, Herman L, Pinto F, Addis RC, Klein D, Massaro-Giordano G, Gearhart JD. Optimal isolation and xeno-free culture conditions for limbal stem cell function. Investigative Ophthalmology & Visual Science. 55: 375-86. PMID 24030457 DOI: 10.1167/Iovs.13-12517  0.413
2013 Sussman RT, Stanek TJ, Esteso P, Gearhart JD, Knudsen KE, McMahon SB. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2). The Journal of Biological Chemistry. 288: 24234-46. PMID 23760504 DOI: 10.1074/Jbc.M113.469783  0.758
2013 Addis RC, Ifkovits JL, Pinto F, Kellam LD, Esteso P, Rentschler S, Christoforou N, Epstein JA, Gearhart JD. Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success. Journal of Molecular and Cellular Cardiology. 60: 97-106. PMID 23591016 DOI: 10.1016/J.Yjmcc.2013.04.004  0.75
2013 Shamblott MJ, Kerr CL, Axelman J, Littlefield JW, Clark GO, Patterson ES, Addis RC, Kraszewski JN, Kent KC, Gearhart JD. Derivation and Differentiation of Human Embryonic Germ Cells Essentials of Stem Cell Biology: Third Edition. 435-451. DOI: 10.1016/B978-0-12-409503-8.00030-5  0.798
2012 Pashai N, Hao H, All A, Gupta S, Chaerkady R, De Los Angeles A, Gearhart JD, Kerr CL. Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells. Plos One. 7: e39088. PMID 22737227 DOI: 10.1371/Journal.Pone.0039088  0.508
2011 Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS. Identification of RNA binding motif proteins essential for cardiovascular development. Bmc Developmental Biology. 11: 62. PMID 22011202 DOI: 10.1186/1471-213X-11-62  0.329
2011 Chaerkady R, Letzen B, Renuse S, Sahasrabuddhe NA, Kumar P, All AH, Thakor NV, Delanghe B, Gearhart JD, Pandey A, Kerr CL. Quantitative temporal proteomic analysis of human embryonic stem cell differentiation into oligodendrocyte progenitor cells. Proteomics. 11: 4007-20. PMID 21770034 DOI: 10.1002/Pmic.201100107  0.484
2011 Esteso P, Gearhart JD. The use of human embryonic stem cells in drug discovery. Counterpoint. Clinical Pharmacology and Therapeutics. 89: 641-3. PMID 21512522 DOI: 10.1038/Clpt.2011.19  0.76
2011 Gearhart J, Coutifaris C. In vitro fertilization, the Nobel Prize, and human embryonic stem cells. Cell Stem Cell. 8: 12-5. PMID 21211779 DOI: 10.1016/J.Stem.2010.12.015  0.462
2011 Hiller M, Liu C, Blumenthal PD, Gearhart JD, Kerr CL. Bone morphogenetic protein 4 mediates human embryonic germ cell derivation. Stem Cells and Development. 20: 351-61. PMID 20486775 DOI: 10.1089/Scd.2010.0084  0.489
2011 Xu HN, Addis RC, Goings DF, Nioka S, Chance B, Gearhart JD, Li LZ. Imaging redox state heterogeneity within individual embryonic stem cell colonies Journal of Innovative Optical Health Sciences. 4: 279-288. DOI: 10.1142/S1793545811001617  0.375
2010 Limpitikul W, Christoforou N, Thompson SA, Gearhart JD, Tung L, Lipke EA. Influence of Electromechanical Activity on Cardiac Differentiation of Mouse Embryonic Stem Cells. Cardiovascular Engineering and Technology. 1: 179-193. PMID 29057018 DOI: 10.1007/S13239-010-0020-8  0.718
2010 Christoforou N, Oskouei BN, Esteso P, Hill CM, Zimmet JM, Bian W, Bursac N, Leong KW, Hare JM, Gearhart JD. Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts. Plos One. 5: e11536. PMID 20634944 DOI: 10.1371/Journal.Pone.0011536  0.775
2010 Letzen BS, Liu C, Thakor NV, Gearhart JD, All AH, Kerr CL. MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells. Plos One. 5: e10480. PMID 20463920 DOI: 10.1371/Journal.Pone.0010480  0.356
2010 Kerr CL, Letzen BS, Hill CM, Agrawal G, Thakor NV, Sterneckert JL, Gearhart JD, All AH. Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury. The International Journal of Neuroscience. 120: 305-13. PMID 20374080 DOI: 10.3109/00207450903585290  0.661
2010 Varghese S, Hwang NS, Ferran A, Hillel A, Theprungsirikul P, Canver AC, Zhang Z, Gearhart J, Elisseeff J. Engineering musculoskeletal tissues with human embryonic germ cell derivatives. Stem Cells (Dayton, Ohio). 28: 765-74. PMID 20178108 DOI: 10.1002/Stem.325  0.499
2010 Chaerkady R, Kerr CL, Kandasamy K, Marimuthu A, Gearhart JD, Pandey A. Comparative proteomics of human embryonic stem cells and embryonal carcinoma cells. Proteomics. 10: 1359-73. PMID 20104618 DOI: 10.1002/Pmic.200900483  0.447
2010 Gearhart JD. The Intersection Between Stem Cell Biology and Reproduction. Biology of Reproduction. 83: 1-1. DOI: 10.1093/Biolreprod/83.S1.1  0.454
2010 Swelstad B, Liu F, Yuan X, Hiller M, Gearhart J, Kerr C. The promise of reprogramming human primordial germ cells for the treatment of infertility Fertility and Sterility. 94: S60. DOI: 10.1016/J.Fertnstert.2010.07.234  0.401
2009 Gearhart JD, Addis RC. The use of animals in human stem cell research: past, present, and future. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 51: 1-2. PMID 20075494 DOI: 10.1093/Ilar.51.1.1  0.42
2009 Chaerkady R, Kerr CL, Marimuthu A, Kelkar DS, Kashyap MK, Gucek M, Gearhart JD, Pandey A. Temporal analysis of neural differentiation using quantitative proteomics. Journal of Proteome Research. 8: 1315-26. PMID 19173612 DOI: 10.1021/Pr8006667  0.42
2009 Regenberg A, Mathews DJ, Blass DM, Bok H, Coyle JT, Duggan P, Faden R, Finkel J, Gearhart JD, Hillis A, Hoke A, Johnson R, Johnston M, Kahn J, Kerr D, et al. The role of animal models in evaluating reasonable safety and efficacy for human trials of cell-based interventions for neurologic conditions. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1-9. PMID 18728679 DOI: 10.1038/Jcbfm.2008.98  0.313
2008 Gearhart J. A decade of stem-cell research. An interview with John Gearhart, Director of the Institute for Regenerative Medicine at the University of Pennsylvania, USA. Interview by Howard Wolinsky. Embo Reports. 10: 12-6. PMID 19079128 DOI: 10.1038/Embor.2008.235  0.389
2008 Gearhart J. Human pluripotent stem cell research: Past, present and future Cell Research. 18. PMID 18679184 DOI: 10.1038/Cr.2008.91  0.439
2008 Jansen JF, Gearhart JD, Bulte JW. Comment on "Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain". Science (New York, N.Y.). 321: 640. PMID 18669846 DOI: 10.1126/Science.1153997  0.301
2008 Patterson ES, Addis RC, Shamblott MJ, Gearhart JD. SOX17 directly activates Zfp202 transcription during in vitro endoderm differentiation. Physiological Genomics. 34: 277-84. PMID 18523156 DOI: 10.1152/Physiolgenomics.90236.2008  0.769
2008 Miller RA, Christoforou N, Pevsner J, McCallion AS, Gearhart JD. Efficient array-based identification of novel cardiac genes through differentiation of mouse ESCs. Plos One. 3: e2176. PMID 18478100 DOI: 10.1371/Journal.Pone.0002176  0.72
2008 Mathews DJ, Sugarman J, Bok H, Blass DM, Coyle JT, Duggan P, Finkel J, Greely HT, Hillis A, Hoke A, Johnson R, Johnston M, Kahn J, Kerr D, Kurtzberg J, ... ... Gearhart JD, et al. Cell-based interventions for neurologic conditions: ethical challenges for early human trials. Neurology. 71: 288-93. PMID 18463365 DOI: 10.1212/01.Wnl.0000316436.13659.80  0.369
2008 Addis RC, Bulte JWM, Gearhart JD. Special cells, special considerations: the challenges of bringing embryonic stem cells from the laboratory to the clinic. Clinical Pharmacology & Therapeutics. 83: 386-389. PMID 18285783 DOI: 10.1038/Sj.Clpt.6100384  0.45
2008 Christoforou N, Miller RA, Hill CM, Jie CC, McCallion AS, Gearhart JD. Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. The Journal of Clinical Investigation. 118: 894-903. PMID 18246200 DOI: 10.1172/Jci33942  0.751
2008 Kerr CL, Hill CM, Blumenthal PD, Gearhart JD. Expression of pluripotent stem cell markers in the human fetal ovary. Human Reproduction (Oxford, England). 23: 589-99. PMID 18203707 DOI: 10.1093/Humrep/Dem411  0.515
2008 Kerr CL, Hill CM, Blumenthal PD, Gearhart JD. Expression of pluripotent stem cell markers in the human fetal testis. Stem Cells (Dayton, Ohio). 26: 412-21. PMID 18024420 DOI: 10.1634/Stemcells.2007-0605  0.515
2007 Gearhart J, Pashos EE, Prasad MK. Pluripotency redux--advances in stem-cell research. The New England Journal of Medicine. 357: 1469-72. PMID 17928593 DOI: 10.1056/Nejmp078126  0.474
2007 Christoforou N, Gearhart JD. Stem cells and their potential in cell-based cardiac therapies. Progress in Cardiovascular Diseases. 49: 396-413. PMID 17498520 DOI: 10.1016/J.Pcad.2007.02.006  0.755
2006 Kerr CL, Shamblott MJ, Gearhart JD. Pluripotent stem cells from germ cells. Methods in Enzymology. 419: 400-26. PMID 17141064 DOI: 10.1016/S0076-6879(06)19016-3  0.515
2006 Kerr CL, Gearhart JD, Elliott AM, Donovan PJ. Embryonic germ cells: when germ cells become stem cells. Seminars in Reproductive Medicine. 24: 304-13. PMID 17123225 DOI: 10.1055/S-2006-952152  0.527
2006 Jansen JF, Shamblott MJ, van Zijl PC, Lehtimäki KK, Bulte JW, Gearhart JD, Hakumäki JM. Stem cell profiling by nuclear magnetic resonance spectroscopy. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 56: 666-70. PMID 16858672 DOI: 10.1002/Mrm.20968  0.463
2006 Frimberger D, Morales N, Gearhart JD, Gearhart JP, Lakshmanan Y. Human embryoid body-derived stem cells in tissue engineering-enhanced migration in co-culture with bladder smooth muscle and urothelium. Urology. 67: 1298-303. PMID 16750247 DOI: 10.1016/J.Urology.2005.12.005  0.48
2006 Onyango P, Jiang S, Uejima H, Shamblott MJ, Gearhart JD, Cui H, Feinberg AP. Erratum: Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages (Proceedings of the National Academy of Sciences of the United States of America (August 6, 2002) 16, 99 (10599-10604) DOI: 10.1073/pnas.152327599) Proceedings of the National Academy of Sciences of the United States of America. 103. DOI: 10.1073/Pnas.0605707103  0.383
2005 Wilmut I, West MD, Lanza RP, Gearhart JD, Smith A, Colman A, Trounson AO, Campbell KH. Human embryonic stem cells. Science (New York, N.Y.). 310: 1903. PMID 16352868 DOI: 10.1126/Science.1123832  0.372
2005 Mueller D, Shamblott MJ, Fox HE, Gearhart JD, Martin LJ. Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage. Journal of Neuroscience Research. 82: 592-608. PMID 16247803 DOI: 10.1002/Jnr.20673  0.424
2005 Greene M, Schill K, Takahashi S, Bateman-House A, Beauchamp T, Bok H, Cheney D, Coyle J, Deacon T, Dennett D, Donovan P, Flanagan O, Goldman S, Greely H, Martin L, ... ... Gearhart J, et al. Ethics: Moral issues of human-non-human primate neural grafting. Science (New York, N.Y.). 309: 385-6. PMID 16020716 DOI: 10.1126/Science.1112207  0.324
2005 Sterneckert JL, Hill CM, Palmer R, Gearhart JD. Bone morphogenetic proteins produced by cells within embryoid bodies inhibit ventral directed differentiation by Sonic Hedgehog. Cloning and Stem Cells. 7: 27-34. PMID 15996115 DOI: 10.1089/Clo.2005.7.27  0.651
2005 Frimberger D, Morales N, Shamblott M, Gearhart JD, Gearhart JP, Lakshmanan Y. Human embryoid body-derived stem cells in bladder regeneration using rodent model. Urology. 65: 827-32. PMID 15833555 DOI: 10.1016/J.Urology.2004.11.024  0.445
2005 Lakshmanan Y, Frimberger D, Gearhart JD, Gearhart JP. Human embryoid body-derived stem cells in co-culture with bladder smooth muscle and urothelium. Urology. 65: 821-6. PMID 15833554 DOI: 10.1016/J.Urology.2004.11.022  0.462
2005 Kim MS, Hwang NS, Lee J, Kim TK, Leong K, Shamblott MJ, Gearhart J, Elisseeff J. Musculoskeletal differentiation of cells derived from human embryonic germ cells. Stem Cells (Dayton, Ohio). 23: 113-23. PMID 15625128 DOI: 10.1634/Stemcells.2004-0110  0.498
2004 Faden RR, Gearhart JD. Facts on stem cells. The Washington Post. A15. PMID 15328610  0.352
2004 Zhan X, Dravid G, Ye Z, Hammond H, Shamblott M, Gearhart J, Cheng L. Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet (London, England). 364: 163-71. PMID 15246729 DOI: 10.1016/S0140-6736(04)16629-4  0.439
2004 Gearhart J. New Human Embryonic Stem-Cell Lines — More Is Better The New England Journal of Medicine. 350: 1275-1276. PMID 14999089 DOI: 10.1056/Nejmp048045  0.429
2004 Shamblott MJ, Kerr CL, Axelman J, Littlefield JW, Clark GO, Patterson ES, Addis RC, Kraszewski JN, Kent KC, Gearhart JD. Derivation and Differentiation of Human Embryonic Germ Cells Handbook of Stem Cells. 1: 459-470. DOI: 10.1016/B978-012436643-5/50052-3  0.801
2003 Faden RR, Dawson L, Bateman-House AS, Agnew DM, Bok H, Brock DW, Chakravarti A, Gao XJ, Greene M, Hansen JA, King PA, O'Brien SJ, Sachs DH, Schill KE, Siegel A, ... ... Gearhart JD, et al. Public stem cell banks: considerations of justice in stem cell research and therapy. The Hastings Center Report. 33: 13-27. PMID 14983554 DOI: 10.2307/3527822  0.553
2003 Siddiqi MA, Kilduff GM, Gearhart JD. Use of a night vision intensifier for direct visualization by eye of far-red and near-infrared fluorescence through an optical microscope. Journal of Microscopy. 212: 132-43. PMID 14629562 DOI: 10.1046/j.1365-2818.2003.01253.x  0.527
2003 Dawson L, Bateman-House AS, Mueller Agnew D, Bok H, Brock DW, Chakravarti A, Greene M, King PA, O'Brien SJ, Sachs DH, Schill KE, Siegel A, Solter D, Suter SM, Verfaillie CM, ... ... Gearhart JD, et al. Safety issues in cell-based intervention trials. Fertility and Sterility. 80: 1077-85. PMID 14607552 DOI: 10.1016/S0015-0282(03)02218-0  0.539
2003 Kerr DA, Lladó J, Shamblott MJ, Maragakis NJ, Irani DN, Crawford TO, Krishnan C, Dike S, Gearhart JD, Rothstein JD. Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5131-40. PMID 12832537 DOI: 10.1523/Jneurosci.23-12-05131.2003  0.389
2002 Shamblott MJ, Bugg EM, Lawler AM, Gearhart JD. Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene Developmental Dynamics. 224: 373-380. PMID 12203729 DOI: 10.1002/Dvdy.10116  0.303
2002 Onyango P, Jiang S, Uejima H, Shamblott MJ, Gearhart JD, Cui H, Feinberg AP. Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages. Proceedings of the National Academy of Sciences of the United States of America. 99: 10599-604. PMID 12114541 DOI: 10.1073/Pnas.152327599  0.515
2002 Hickman TN, Shih LM, Zacur HA, Kurman RJ, Diener-West M, Gearhart JD. Decreased progesterone receptor expression in the intermediate trophoblastic cells of spontaneous abortions. Fertility and Sterility. 77: 1001-5. PMID 12009358 DOI: 10.1016/S0015-0282(02)02953-9  0.304
2001 Vlahos NP, Bugg EM, Shamblott MJ, Phelps JY, Gearhart JD, Zacur HA. Prolactin receptor gene expression and immunolocalization of the prolactin receptor in human luteinized granulosa cells Molecular Human Reproduction. 7: 1033-1038. PMID 11675469 DOI: 10.1093/Molehr/7.11.1033  0.327
2001 Shamblott MJ, Axelman J, Littlefield JW, Blumenthal PD, Huggins GR, Cui Y, Cheng L, Gearhart JD. Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro Proceedings of the National Academy of Sciences. 98: 113-118. DOI: 10.1073/Pnas.98.1.113  0.519
2000 Call LM, Moore CS, Stetten G, Gearhart JD. A cre-lox recombination system for the targeted integration of circular yeast artificial chromosomes into embryonic stem cells. Human Molecular Genetics. 9: 1745-51. PMID 10915762 DOI: 10.1093/Hmg/9.12.1745  0.369
2000 Edwards BE, Gearhart JD, Wallach EE. The human pluripotent stem cell: impact on medicine and society. Fertility and Sterility. 74: 1-7. PMID 10899488 DOI: 10.1016/S0015-0282(00)00583-5  0.476
2000 Wang S, Gearhart JD. Human Pluripotential Stem Cells Neoreviews. 1: 132e-136. DOI: 10.1542/Neo.1-7-E132  0.41
1999 Litingtung Y, Lawler AM, Sebald SM, Lee E, Gearhart JD, Westphal H, Corden JL. Growth retardation and neonatal lethality in mice with a homozygous deletion in the C-terminal domain of RNA polymerase II. Molecular & General Genetics : Mgg. 261: 100-5. PMID 10071215 DOI: 10.1007/S004380050946  0.38
1999 Moore CS, Mjaatvedt CH, Gearhart JD. Expression and function of activin beta A during mouse cardiac cushion tissue formation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 212: 548-62. PMID 9707328 DOI: 10.1002/(Sici)1097-0177(199808)212:4<548::Aid-Aja8>3.0.Co;2-H  0.408
1999 Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD, Huggins GR, Gearhart JD. Derivation of Pluripotent Stem Cells From Cultured Human Primordial Germ Cells Obstetrical & Gynecological Survey. 54: 177-178. DOI: 10.1097/00006254-199903000-00018  0.491
1998 Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD, Huggins GR, Gearhart JD. Derivation of pluripotent stem cells from cultured human primordial germ cells Proceedings of the National Academy of Sciences of the United States of America. 95: 13726-13731. PMID 9811868 DOI: 10.1073/Pnas.95.23.13726  0.507
1998 Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, Semenza GL. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes & Development. 12: 149-62. PMID 9436976 DOI: 10.1101/Gad.12.2.149  0.361
1998 Mishra L, Cai T, Levine A, Weng D, Mezey E, Mishra B, Gearhart J. Identification of elf1, a beta-spectrin, in early mouse liver development. The International Journal of Developmental Biology. 42: 221-224. DOI: 10.1387/Ijdb.9551868  0.332
1997 Shih IM, Schnaar RL, Gearhart JD, Kurman RJ. Distribution of cells bearing the HNK-1 epitope in the human placenta Placenta. 18: 667-674. PMID 9364602 DOI: 10.1016/S0143-4004(97)90008-4  0.365
1997 Schwindinger WF, Reese KJ, Lawler AM, Gearhart JD, Levine MA. Targeted disruption of Gnas in embryonic stem cells. Endocrinology. 138: 4058-63. PMID 9322912 DOI: 10.1210/Endo.138.10.5439  0.346
1997 Montrose-Rafizadeh C, Kole J, Bartkowski LM, Lee LH, Blackmon DL, Behnken SE, Gearhart JD, Cohn JA, Montrose MH. Gene targeting of a CFTR allele in HT29 human epithelial cells. Journal of Cellular Physiology. 170: 299-308. PMID 9066787 DOI: 10.1002/(Sici)1097-4652(199703)170:3<299::Aid-Jcp11>3.0.Co;2-A  0.331
1996 Rosenberg C, Voltz AK, Lawler AM, Lamb BT, Stetten G, Gearhart JD. Alterations of yeast artificial chromosome transgenic sequences in stretched embryonic stem-cell chromatin visualized by fluorescence in situ hybridization. Cytogenetics and Cell Genetics. 75: 67-70. PMID 8995492 DOI: 10.1159/000134459  0.396
1995 Bustin M, Alfonso PJ, Pash JM, Ward JM, Gearhart JD, Reeves RH. Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin. Dna and Cell Biology. 14: 997-1005. PMID 8534374 DOI: 10.1089/Dna.1995.14.997  0.325
1995 Lamb BT, Gearhart JD. YAC transgenics and the study of genetics and human disease. Current Opinion in Genetics & Development. 5: 342-8. PMID 7549429 DOI: 10.1016/0959-437X(95)80049-2  0.353
1993 Ezaki O, Flores-Riveros JR, Kaestner KH, Gearhart J, Lane MD. Regulated expression of an insulin-responsive glucose transporter (GLUT4) minigene in 3T3-L1 adipocytes and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 3348-52. PMID 8475079 DOI: 10.1073/Pnas.90.8.3348  0.324
1993 Urven LE, Weng DE, Schumaker AL, Gearhart JD, McCarrey JR. Differential gene expression in fetal mouse germ cells Biology of Reproduction. 48: 564-574. PMID 8452933 DOI: 10.1095/Biolreprod48.3.564  0.483
1993 Lamb BT, Sisodia SS, Lawler AM, Slunt HH, Kitt CA, Kearns WG, Pearson PL, Price DL, Gearhart JD. Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]. Nature Genetics. 5: 22-30. PMID 8220418 DOI: 10.1038/Ng0993-22  0.353
1992 Wang Y, Macke JP, Merbs SL, Zack DJ, Klaunberg B, Bennett J, Gearhart J, Nathans J. A locus control region adjacent to the human red and green visual pigment genes. Neuron. 9: 429-40. PMID 1524826 DOI: 10.1016/0896-6273(92)90181-C  0.491
1991 Semenza GL, Koury ST, Nejfelt MK, Gearhart JD, Antonarakis SE. Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 88: 8725-9. PMID 1924331 DOI: 10.1073/Pnas.88.19.8725  0.379
1991 Fisher S, Gearhart JD, Oster-Granite ML. Expression of the amyloid precursor protein gene in mouse oocytes and embryos. Proceedings of the National Academy of Sciences of the United States of America. 88: 1779-82. PMID 1900367 DOI: 10.1073/Pnas.88.5.1779  0.348
1990 Semenza GL, Dureza RC, Traystman MD, Gearhart JD, Antonarakis SE. Human erythropoietin gene expression in transgenic mice: multiple transcription initiation sites and cis-acting regulatory elements. Molecular and Cellular Biology. 10: 930-8. PMID 2304468 DOI: 10.1128/mcb.10.3.930-938.1990  0.324
1989 Semenza GL, Traystman MD, Gearhart JD, Antonarakis SE. Polycythemia in transgenic mice expressing the human erythropoietin gene. Proceedings of the National Academy of Sciences of the United States of America. 86: 2301-5. PMID 2928334 DOI: 10.1073/Pnas.86.7.2301  0.328
1989 Reeves RH, Gearhart JD, Hecht NB, Yelick P, Johnson P, O'brien SJ. Mapping of PRM 1 to human chromosome 16 and tight linkage of Prm-1 and Prm-2 on mouse chromosome 16 Journal of Heredity. 80: 442-446. PMID 2614060 DOI: 10.1093/Oxfordjournals.Jhered.A110895  0.406
1989 O'Hara BF, Fisher S, Oster-Granite ML, Gearhart JD, Reeves RH. Developmental expression of the amyloid precursor protein, growth-associated protein 43, and somatostatin in normal and trisomy 16 mice. Brain Research. Developmental Brain Research. 49: 300-4. PMID 2572360 DOI: 10.1016/0165-3806(89)90031-X  0.305
1988 O'Hara BF, Bendotti C, Reeves RH, Oster-Granite ML, Coyle JT, Gearhart JD. Genetic mapping and analysis of somatostatin expression in Snell dwarf mice. Brain Research. 464: 283-92. PMID 2906811 DOI: 10.1016/0169-328X(88)90037-X  0.303
1988 Bendotti C, Forloni GL, Morgan RA, O'Hara BF, Oster-Granite ML, Reeves RH, Gearhart JD, Coyle JT. Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid, and lesioned mice. Proceedings of the National Academy of Sciences of the United States of America. 85: 3628-32. PMID 2897124 DOI: 10.1073/Pnas.85.10.3628  0.301
1987 Gearhart JD, Oster-Granite ML, Reeves RH, Coyle JT. Developmental consequences of autosomal aneuploidy in mammals. Developmental Genetics. 8: 249-65. PMID 2971493 DOI: 10.1002/Dvg.1020080408  0.306
1986 Gearhart JD, Singer HS, Moran TH, Tiemeyer M, Oster-Granite ML, Coyle JT. Mouse chimeras composed of trisomy 16 and normal (2N) cells: preliminary studies. Brain Research Bulletin. 16: 815-24. PMID 2875771 DOI: 10.1016/0361-9230(86)90077-8  0.401
1985 Deloia J, Marban L, Gearhart J, Littlefield JW. 814 Expression Of A Bacterial Gene In Transgenic Mice Pediatric Research. 19. DOI: 10.1203/00006450-198504000-00844  0.333
1984 Singer HS, Tiemeyer M, Hedreen JC, Gearhart J, Coyle JT. Morphologic and neurochemical studies of embryonic brain development in murine trisomy 16. Brain Research. 317: 155-66. PMID 6148129 DOI: 10.1016/0165-3806(84)90093-2  0.307
1981 Gearhart J, Oster-Granite ML. Glucosephosphate isomerase distribution during oocyte maturation and early embryologic stages of the mouse. Biology of Reproduction. 23: 837-45. PMID 7448284 DOI: 10.1095/Biolreprod23.4.837  0.372
1981 Gearhart J, Oster-Granite ML. Reproduction in a population of chimeric mice: relationship of chromosomal sex to functional germ cells and proportions of chimeric components in several tissues. Biology of Reproduction. 24: 713-22. PMID 7248407 DOI: 10.1095/Biolreprod24.4.713  0.322
1981 Oster-Granite ML, Gearhart J. Cell lineage analysis of cerebellar Purkinje cells in mouse chimeras. Developmental Biology. 85: 199-208. PMID 7018958 DOI: 10.1016/0012-1606(81)90251-7  0.433
1980 Oster-Granite ML, Gearhart J. Immunofluorescence and histochemical localization of glucosephosphate isomerase in neural tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 28: 250-4. PMID 6986435 DOI: 10.1177/28.3.6986435  0.324
1979 Gearhart J, Oster-Granite ML. Antibodies to allozymes as potential cell markers for chimeric mouse studies. Basic Life Sciences. 12: 111-22. PMID 378215 DOI: 10.1007/978-1-4684-3390-6_9  0.444
1977 Dewey MJ, Gearhart JD, Mintz B. Cell surface antigens of totipotent mouse teratocarcinoma cells grown in vivo: their relation to embryo, adult, and tumor antigens. Developmental Biology. 55: 359-74. PMID 190068 DOI: 10.1016/0012-1606(77)90179-8  0.606
1975 Gearhart JD, Mintz B. Creatine kinase, myokinase, and acetylcholinesterase activities in muscle-forming primary cultures of mouse teratocarcinoma cells. Cell. 6: 61-6. PMID 170002 DOI: 10.1016/0092-8674(75)90074-4  0.562
1974 Gearhart JD, Mintz B. Contact-mediated myogenesis and increased acetylcholinesterase activity in primary cultures of mouse teratocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 71: 1734-8. PMID 4525289 DOI: 10.1073/Pnas.71.5.1734  0.642
1973 Mintz B, Gearhart JD, Guymont AO. Phytohemagglutinin-mediated blastomere aggregation and development of allophenic mice. Developmental Biology. 31: 195-9. PMID 4787188 DOI: 10.1016/0012-1606(73)90331-X  0.547
1973 Mintz B, Gearhart JD. Subnormal zona pellucida change in parthenogenetic mouse embryos. Developmental Biology. 31: 178-84. PMID 4787186 DOI: 10.1016/0012-1606(73)90328-X  0.528
1972 Gearhart JD, Mintz B. Glucosephosphate isomerase subunit-reassociation tests for maternal-fetal and fetal-fetal cell fusion in the mouse placenta. Developmental Biology. 29: 55-64. PMID 5074214 DOI: 10.1016/0012-1606(72)90043-7  0.581
1972 Gearhart JD, Mintz B. Clonal origins of somites and their muscle derivatives: evidence from allophenic mice. Developmental Biology. 29: 27-37. PMID 5074211 DOI: 10.1016/0012-1606(72)90040-1  0.559
1971 Gearhart JD, MacIntyre RJ. Lack of intercellular suppression of position-effect variegation by supernumerary Y chromosomes during cell differentiation in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 68: 13-5. PMID 5276286 DOI: 10.1073/Pnas.68.1.13  0.343
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