| Year |
Citation |
Score |
| 2020 |
Zhao H, Li Z, Zhu Y, Bian S, Zhang Y, Qin L, Naik AK, He J, Zhang Z, Krangel MS, Hao B. A role of the CTCF binding site at enhancer Eα in the dynamic chromatin organization of the Tcra-Tcrd locus. Nucleic Acids Research. PMID 32853367 DOI: 10.1093/nar/gkaa711 |
0.327 |
|
| 2019 |
Naik AK, Byrd AT, Lucander ACK, Krangel MS. Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4CD8 thymocytes. The Journal of Experimental Medicine. 216: 231-243. PMID 30545902 DOI: 10.1084/jem.20181402 |
0.316 |
|
| 2018 |
Chen S, Krangel MS. Diversification of the TCR β Locus V Repertoire by CTCF. Immunohorizons. 2: 377-383. PMID 30957077 DOI: 10.4049/immunohorizons.1800072 |
0.429 |
|
| 2018 |
Chen S, Luperchio TR, Wong X, Doan EB, Byrd AT, Roy Choudhury K, Reddy KL, Krangel MS. A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus. Cell Reports. 25: 1729-1740.e6. PMID 30428344 DOI: 10.1016/J.Celrep.2018.10.052 |
0.363 |
|
| 2018 |
Loguercio S, Barajas-Mora EM, Shih HY, Krangel MS, Feeney AJ. Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci. Frontiers in Immunology. 9: 425. PMID 29593713 DOI: 10.3389/Fimmu.2018.00425 |
0.687 |
|
| 2016 |
Chen L, Zhao L, Alt FW, Krangel MS. An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments. Journal of Immunology (Baltimore, Md. : 1950). PMID 27613698 DOI: 10.4049/Jimmunol.1601124 |
0.393 |
|
| 2016 |
Zhao L, Frock RL, Du Z, Hu J, Chen L, Krangel MS, Alt FW. Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development. The Journal of Experimental Medicine. PMID 27526713 DOI: 10.1084/Jem.20160670 |
0.339 |
|
| 2016 |
Krangel MS. The Ties that Bind (the Igh Locus). Trends in Genetics : Tig. 32: 253-5. PMID 27012539 DOI: 10.1016/j.tig.2016.03.003 |
0.329 |
|
| 2015 |
Carico Z, Krangel MS. Chromatin Dynamics and the Development of the TCRα and TCRδ Repertoires. Advances in Immunology. 128: 307-61. PMID 26477370 DOI: 10.1016/bs.ai.2015.07.005 |
0.399 |
|
| 2015 |
Chen L, Carico Z, Shih HY, Krangel MS. A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires. Nature Immunology. 16: 1085-93. PMID 26258942 DOI: 10.1038/Ni.3232 |
0.725 |
|
| 2015 |
Hao B, Naik AK, Watanabe A, Tanaka H, Chen L, Richards HW, Kondo M, Taniuchi I, Kohwi Y, Kohwi-Shigematsu T, Krangel MS. An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development. The Journal of Experimental Medicine. 212: 809-24. PMID 25847946 DOI: 10.1084/Jem.20142207 |
0.329 |
|
| 2015 |
del Blanco B, Angulo Ú, Krangel MS, Hernández-Munain C. T-cell receptor α enhancer is inactivated in αβ T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 112: E1744-53. PMID 25831496 DOI: 10.1073/pnas.1406551112 |
0.327 |
|
| 2015 |
Boudil A, Matei IR, Shih HY, Bogdanoski G, Yuan JS, Chang SG, Montpellier B, Kowalski PE, Voisin V, Bashir S, Bader GD, Krangel MS, Guidos CJ. IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection. Nature Immunology. 16: 397-405. PMID 25729925 DOI: 10.1038/Ni.3122 |
0.624 |
|
| 2015 |
Majumder K, Koues OI, Chan EA, Kyle KE, Horowitz JE, Yang-Iott K, Bassing CH, Taniuchi I, Krangel MS, Oltz EM. Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element. The Journal of Experimental Medicine. 212: 107-20. PMID 25512470 DOI: 10.1084/Jem.20141479 |
0.328 |
|
| 2015 |
Naik AK, Hawwari A, Krangel MS. Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters. Journal of Immunology (Baltimore, Md. : 1950). 194: 790-4. PMID 25472997 DOI: 10.4049/jimmunol.1402423 |
0.362 |
|
| 2015 |
Chen L, Carico Z, Shih HY, Krangel MS. A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires Nature Immunology. DOI: 10.1038/ni.3232 |
0.673 |
|
| 2013 |
Chan EA, Teng G, Corbett E, Choudhury KR, Bassing CH, Schatz DG, Krangel MS. Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. Proceedings of the National Academy of Sciences of the United States of America. 110: E4628-37. PMID 24218622 DOI: 10.1073/Pnas.1310846110 |
0.375 |
|
| 2013 |
Shih HY, Krangel MS. Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci. Journal of Immunology (Baltimore, Md. : 1950). 190: 4915-21. PMID 23645930 DOI: 10.4049/Jimmunol.1300218 |
0.705 |
|
| 2012 |
Shih HY, Verma-Gaur J, Torkamani A, Feeney AJ, Galjart N, Krangel MS. Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. Proceedings of the National Academy of Sciences of the United States of America. 109: E3493-502. PMID 23169622 DOI: 10.1073/Pnas.1214131109 |
0.695 |
|
| 2012 |
Callen E, Faryabi RB, Luckey M, Hao B, Daniel JA, Yang W, Sun HW, Dressler G, Peng W, Chi H, Ge K, Krangel MS, Park JH, Nussenzweig A. The DNA Damage- and Transcription-Associated Protein Paxip1 Controls Thymocyte Development and Emigration Immunity. 37: 971-985. PMID 23159437 DOI: 10.1016/J.Immuni.2012.10.007 |
0.385 |
|
| 2012 |
Seitan VC, Krangel MS, Merkenschlager M. Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement. Trends in Immunology. 33: 153-9. PMID 22440186 DOI: 10.1016/j.it.2012.02.004 |
0.303 |
|
| 2011 |
Kondilis-Mangum HD, Shih HY, Mahowald G, Sleckman BP, Krangel MS. Regulation of TCRβ allelic exclusion by gene segment proximity and accessibility. Journal of Immunology (Baltimore, Md. : 1950). 187: 6374-81. PMID 22079986 DOI: 10.4049/Jimmunol.1102611 |
0.694 |
|
| 2011 |
Seitan VC, Hao B, Tachibana-Konwalski K, Lavagnolli T, Mira-Bontenbal H, Brown KE, Teng G, Carroll T, Terry A, Horan K, Marks H, Adams DJ, Schatz DG, Aragon L, Fisher AG, ... Krangel MS, et al. A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature. 476: 467-71. PMID 21832993 DOI: 10.1038/Nature10312 |
0.358 |
|
| 2011 |
Hao B, Krangel MS. Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer. Journal of Immunology (Baltimore, Md. : 1950). 187: 2484-91. PMID 21784972 DOI: 10.4049/jimmunol.1100468 |
0.384 |
|
| 2011 |
Carabana J, Watanabe A, Hao B, Krangel MS. A barrier-type insulator forms a boundary between active and inactive chromatin at the murine TCRβ locus. Journal of Immunology (Baltimore, Md. : 1950). 186: 3556-62. PMID 21317385 DOI: 10.4049/jimmunol.1003164 |
0.363 |
|
| 2011 |
Shih HY, Hao B, Krangel MS. Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization. Immunologic Research. 49: 192-201. PMID 21128009 DOI: 10.1007/S12026-010-8181-Y |
0.71 |
|
| 2010 |
Ji Y, Little AJ, Banerjee JK, Hao B, Oltz EM, Krangel MS, Schatz DG. Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination. The Journal of Experimental Medicine. 207: 2809-16. PMID 21115692 DOI: 10.1084/Jem.20101136 |
0.364 |
|
| 2010 |
Shih HY, Krangel MS. Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination. The Journal of Experimental Medicine. 207: 1835-41. PMID 20696701 DOI: 10.1084/Jem.20100772 |
0.714 |
|
| 2010 |
Kondilis-Mangum HD, Cobb RM, Osipovich O, Srivatsan S, Oltz EM, Krangel MS. Transcription-dependent mobilization of nucleosomes at accessible TCR gene segments in vivo. Journal of Immunology (Baltimore, Md. : 1950). 184: 6970-7. PMID 20483751 DOI: 10.4049/Jimmunol.0903923 |
0.748 |
|
| 2009 |
Vazquez BN, Laguna T, Carabana J, Krangel MS, Lauzurica P. CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements. Journal of Immunology (Baltimore, Md. : 1950). 183: 6513-21. PMID 19841192 DOI: 10.4049/jimmunol.0900839 |
0.306 |
|
| 2009 |
Abarrategui I, Krangel MS. Germline transcription: a key regulator of accessibility and recombination. Advances in Experimental Medicine and Biology. 650: 93-102. PMID 19731804 |
0.368 |
|
| 2009 |
Krangel MS. Mechanics of T cell receptor gene rearrangement. Current Opinion in Immunology. 21: 133-9. PMID 19362456 DOI: 10.1016/j.coi.2009.03.009 |
0.406 |
|
| 2008 |
Schlimgen RJ, Reddy KL, Singh H, Krangel MS. Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nature Immunology. 9: 802-9. PMID 18536719 DOI: 10.1038/Ni.1624 |
0.726 |
|
| 2007 |
Abarrategui I, Krangel MS. Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination. The Embo Journal. 26: 4380-90. PMID 17882258 DOI: 10.1038/sj.emboj.7601866 |
0.324 |
|
| 2007 |
Hager E, Hawwari A, Matsuda JL, Krangel MS, Gapin L. Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development. Journal of Immunology (Baltimore, Md. : 1950). 179: 2228-34. PMID 17675483 DOI: 10.4049/jimmunol.179.4.2228 |
0.319 |
|
| 2007 |
Krangel MS. T cell development: better living through chromatin. Nature Immunology. 8: 687-94. PMID 17579647 DOI: 10.1038/ni1484 |
0.362 |
|
| 2007 |
Hawwari A, Krangel MS. Role for rearranged variable gene segments in directing secondary T cell receptor alpha recombination. Proceedings of the National Academy of Sciences of the United States of America. 104: 903-7. PMID 17210914 DOI: 10.1073/pnas.0608248104 |
0.35 |
|
| 2007 |
Roberts JL, Lauritsen JP, Cooney M, Parrott RE, Sajaroff EO, Win CM, Keller MD, Carpenter JH, Carabana J, Krangel MS, Sarzotti M, Zhong XP, Wiest DL, Buckley RH. T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. Blood. 109: 3198-206. PMID 17170122 DOI: 10.1016/J.Jaci.2006.11.298 |
0.592 |
|
| 2006 |
Abarrategui I, Krangel MS. Regulation of T cell receptor-alpha gene recombination by transcription. Nature Immunology. 7: 1109-15. PMID 16936730 DOI: 10.1038/ni1379 |
0.344 |
|
| 2006 |
Jackson AM, Krangel MS. A role for MAPK in feedback inhibition of Tcrb recombination. Journal of Immunology (Baltimore, Md. : 1950). 176: 6824-30. PMID 16709842 DOI: 10.4049/Jimmunol.176.11.6824 |
0.623 |
|
| 2006 |
Jackson AM, Krangel MS. Turning T-cell receptor beta recombination on and off: more questions than answers. Immunological Reviews. 209: 129-41. PMID 16448539 DOI: 10.1111/J.0105-2896.2006.00342.X |
0.626 |
|
| 2005 |
Jackson AM, Krangel MS. Allele-specific regulation of TCR beta variable gene segment chromatin structure. Journal of Immunology (Baltimore, Md. : 1950). 175: 5186-91. PMID 16210623 DOI: 10.4049/Jimmunol.175.8.5186 |
0.651 |
|
| 2005 |
Hawwari A, Krangel MS. Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure. The Journal of Experimental Medicine. 202: 467-72. PMID 16087716 DOI: 10.1084/jem.20050680 |
0.372 |
|
| 2005 |
Carabana J, Ortigoza E, Krangel MS. Regulation of the murine Ddelta2 promoter by upstream stimulatory factor 1, Runx1, and c-Myb. Journal of Immunology (Baltimore, Md. : 1950). 174: 4144-52. PMID 15778374 |
0.327 |
|
| 2005 |
Jackson A, Kondilis HD, Khor B, Sleckman BP, Krangel MS. Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. Nature Immunology. 6: 189-97. PMID 15640803 DOI: 10.1038/Ni1157 |
0.572 |
|
| 2004 |
Balmelle N, Zamarreño N, Krangel MS, Hernández-Munain C. Developmental activation of the TCR alpha enhancer requires functional collaboration among proteins bound inside and outside the core enhancer. Journal of Immunology (Baltimore, Md. : 1950). 173: 5054-63. PMID 15470049 |
0.328 |
|
| 2004 |
Krangel MS, Carabana J, Abbarategui I, Schlimgen R, Hawwari A. Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus. Immunological Reviews. 200: 224-32. PMID 15242408 DOI: 10.1111/J.0105-2896.2004.00155.X |
0.774 |
|
| 2004 |
Osipovich O, Milley R, Meade A, Tachibana M, Shinkai Y, Krangel MS, Oltz EM. Targeted inhibition of V(D)J recombination by a histone methyltransferase. Nature Immunology. 5: 309-16. PMID 14985714 DOI: 10.1038/ni1042 |
0.386 |
|
| 2003 |
Krangel MS. Gene segment selection in V(D)J recombination: accessibility and beyond. Nature Immunology. 4: 624-30. PMID 12830137 DOI: 10.1038/ni0703-624 |
0.411 |
|
| 2003 |
Krangel MS, Schlissel MS. Allelic Exclusion, Isotypic Exclusion, and the Developmental Regulation of V(D)J Recombination Molecular Biology of B Cells. 127-140. DOI: 10.1016/B978-012053641-2/50009-5 |
0.377 |
|
| 2002 |
Hernández-Munain C, Krangel MS. Distinct roles for c-Myb and core binding factor/polyoma enhancer-binding protein 2 in the assembly and function of a multiprotein complex on the TCR delta enhancer in vivo. Journal of Immunology (Baltimore, Md. : 1950). 169: 4362-9. PMID 12370369 |
0.334 |
|
| 2002 |
Sikes ML, Meade A, Tripathi R, Krangel MS, Oltz EM. Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility. Proceedings of the National Academy of Sciences of the United States of America. 99: 12309-14. PMID 12196630 DOI: 10.1073/Pnas.182166699 |
0.43 |
|
| 2002 |
Tripathi R, Jackson A, Krangel MS. A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion. Journal of Immunology (Baltimore, Md. : 1950). 168: 2316-24. PMID 11859121 DOI: 10.4049/Jimmunol.168.5.2316 |
0.6 |
|
| 2001 |
Sleckman BP, Carabana J, Zhong X, Krangel MS. Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus. Immunology. 104: 11-8. PMID 11576215 DOI: 10.1046/J.1365-2567.2001.01304.X |
0.641 |
|
| 2001 |
Krangel MS, McMurry MT, Hernandez-Munain C, Zhong XP, Carabana J. Accessibility control of T cell receptor gene rearrangement in developing thymocytes. The TCR alpha/delta locus. Immunologic Research. 22: 127-35. PMID 11339350 DOI: 10.1385/Ir:22:2-3:127 |
0.69 |
|
| 1999 |
Zhong XP, Carabaña J, Krangel MS. Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination. Proceedings of the National Academy of Sciences of the United States of America. 96: 11970-5. PMID 10518560 DOI: 10.1073/Pnas.96.21.11970 |
0.66 |
|
| 1999 |
Hernández-Munain C, Sleckman BP, Krangel MS. A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation. Immunity. 10: 723-33. PMID 10403647 DOI: 10.1016/S1074-7613(00)80071-0 |
0.322 |
|
| 1998 |
Krangel MS, Hernandez-Munain C, Lauzurica P, McMurry M, Roberts JL, Zhong XP. Developmental regulation of V(D)J recombination at the TCR alpha/delta locus. Immunological Reviews. 165: 131-47. PMID 9850858 DOI: 10.1111/J.1600-065X.1998.Tb01236.X |
0.661 |
|
| 1997 |
McMurry MT, Hernandez-Munain C, Lauzurica P, Krangel MS. Enhancer control of local accessibility to V(D)J recombinase. Molecular and Cellular Biology. 17: 4553-61. PMID 9234713 DOI: 10.1128/MCB.17.8.4553 |
0.362 |
|
| 1997 |
Zhong XP, Krangel MS. An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus. Proceedings of the National Academy of Sciences of the United States of America. 94: 5219-24. PMID 9144218 DOI: 10.1073/Pnas.94.10.5219 |
0.639 |
|
| 1997 |
Lauzurica P, Zhong XP, Krangel MS, Roberts JL. Regulation of T cell receptor delta gene rearrangement by CBF/PEBP2. The Journal of Experimental Medicine. 185: 1193-201. PMID 9104806 DOI: 10.1084/Jem.185.7.1193 |
0.608 |
|
| 1996 |
Redondo JM, Hernandez-Munain C, Krangel MS. Transcriptional regulation of the human T cell receptor delta gene. Immunobiology. 193: 288-92. PMID 8530157 DOI: 10.1016/S0171-2985(11)80557-7 |
0.353 |
|
| 1994 |
Lauzurica P, Krangel MS. Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene. The Journal of Experimental Medicine. 179: 43-55. PMID 8270882 DOI: 10.1084/JEM.179.1.43 |
0.394 |
|
| 1991 |
Spits H, Yssel H, Brockelhurst C, Krangel M. Evidence for controlled gene rearrangements and cytokine production during development of human TCR gamma delta+ lymphocytes. Current Topics in Microbiology and Immunology. 173: 47-55. PMID 1833159 DOI: 10.1007/978-3-642-76492-9_8 |
0.347 |
|
| 1990 |
Krangel MS, Yssel H, Brocklehurst C, Spits H. A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production. The Journal of Experimental Medicine. 172: 847-59. PMID 2167345 DOI: 10.1084/JEM.172.3.847 |
0.328 |
|
| 1990 |
Redondo JM, Hata S, Brocklehurst C, Krangel MS. A T cell-specific transcriptional enhancer within the human T cell receptor delta locus. Science (New York, N.Y.). 247: 1225-9. PMID 2156339 DOI: 10.1126/SCIENCE.2156339 |
0.377 |
|
| 1989 |
Hata S, Clabby M, Devlin P, Spits H, De Vries JE, Krangel MS. Diversity and organization of human T cell receptor delta variable gene segments. The Journal of Experimental Medicine. 169: 41-57. PMID 2521243 DOI: 10.1084/JEM.169.1.41 |
0.35 |
|
| 1989 |
Brenner MB, Hochstenbach F, Band H, Parker C, McLean J, Hata S, Krangel M. Human T cell receptor gamma delta structure. Advances in Experimental Medicine and Biology. 254: 17-19. DOI: 10.1007/978-1-4757-5803-0_2 |
0.354 |
|
| 1988 |
Hata S, Satyanarayana K, Devlin P, Band H, McLean J, Strominger JL, Brenner MB, Krangel MS. Extensive junctional diversity of rearranged human T cell receptor delta genes. Science (New York, N.Y.). 240: 1541-4. PMID 3259726 DOI: 10.1126/science.3259726 |
0.368 |
|
| 1988 |
Satyanarayana K, Hata S, Devlin P, Roncarolo MG, De Vries JE, Spits H, Strominger JL, Krangel MS. Genomic organization of the human T-cell antigen-receptor alpha/delta locus. Proceedings of the National Academy of Sciences of the United States of America. 85: 8166-70. PMID 3186718 DOI: 10.1073/Pnas.85.21.8166 |
0.349 |
|
| 1987 |
Modlin RL, Brenner MB, Krangel MS, Duby AD, Bloom BR. T-cell receptors of human suppressor cells Nature. 329: 541-545. PMID 2958712 DOI: 10.1038/329541A0 |
0.305 |
|
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