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Han-Yu Shih, Ph.D. - Publications

Affiliations: 
2012 Immunology Duke University, Durham, NC 
Area:
Immunology
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35/47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cannons JL, Villarino AV, Kapnick SM, Preite S, Shih HY, Gomez-Rodriguez J, Kaul Z, Shibata H, Reilley JM, Huang B, Handon R, McBain IT, Gossa S, Wu T, Su HC, et al. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8 T cells at the expense of central memory. Cell Reports. 37: 109804. PMID 34644563 DOI: 10.1016/j.celrep.2021.109804  0.569
2021 Morrison TA, Hudson WH, Chisolm DA, Kanno Y, Shih HY, Ahmed R, Henao-Mejia J, Hafner M, O'Shea JJ. Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory. Cold Spring Harbor Perspectives in Biology. PMID 34001528 DOI: 10.1101/cshperspect.a037952  0.484
2021 Fernando N, Sciumè G, O'Shea JJ, Shih HY. Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes. Frontiers in Immunology. 12: 655590. PMID 33841440 DOI: 10.3389/fimmu.2021.655590  0.607
2021 Mikami Y, Philips RL, Sciumè G, Petermann F, Meylan F, Nagashima H, Yao C, Davis FP, Brooks SR, Sun HW, Takahashi H, Poholek AC, Shih HY, Afzali B, Muljo SA, et al. MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23. Immunity. PMID 33657395 DOI: 10.1016/j.immuni.2021.02.015  0.434
2020 Sciumè G, Mikami Y, Jankovic D, Nagashima H, Villarino AV, Morrison T, Yao C, Signorella S, Sun HW, Brooks SR, Fang D, Sartorelli V, Nakayamada S, Hirahara K, Zitti B, ... ... Shih HY, et al. Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells. Immunity. PMID 33010223 DOI: 10.1016/j.immuni.2020.09.008  0.577
2019 Göschl L, Preglej T, Boucheron N, Saferding V, Müller L, Platzer A, Hirahara K, Shih HY, Backlund J, Matthias P, Niederreiter B, Hladik A, Kugler M, Gualdoni GA, Scheinecker C, et al. Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis. Journal of Autoimmunity. 102379. PMID 31883829 DOI: 10.1016/J.Jaut.2019.102379  0.412
2019 Petermann F, Pękowska A, Johnson CA, Jankovic D, Shih HY, Jiang K, Hudson WH, Brooks SR, Sun HW, Villarino AV, Yao C, Singleton K, Akondy RS, Kanno Y, Sher A, et al. The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Molecular Cell. PMID 31377117 DOI: 10.1016/J.Molcel.2019.06.025  0.568
2019 Nagashima H, Mahlakõiv T, Shih HY, Davis FP, Meylan F, Huang Y, Harrison OJ, Yao C, Mikami Y, Urban JF, Caron KM, Belkaid Y, Kanno Y, Artis D, O'Shea JJ. Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation. Immunity. PMID 31353223 DOI: 10.1016/J.Immuni.2019.06.009  0.57
2019 Yao C, Sun HW, Lacey NE, Ji Y, Moseman EA, Shih HY, Heuston EF, Kirby M, Anderson S, Cheng J, Khan O, Handon R, Reilley J, Fioravanti J, Hu J, et al. Single-cell RNA-seq reveals TOX as a key regulator of CD8 T cell persistence in chronic infection. Nature Immunology. PMID 31209400 DOI: 10.1038/S41590-019-0403-4  0.626
2019 Kobayashi T, Voisin B, Kim DY, Kennedy EA, Jo JH, Shih HY, Truong A, Doebel T, Sakamoto K, Cui CY, Schlessinger D, Moro K, Nakae S, Horiuchi K, Zhu J, et al. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium. Cell. PMID 30712873 DOI: 10.1016/J.Cell.2018.12.031  0.359
2019 Schwartz DM, Farley TK, Richoz N, Yao C, Shih HY, Petermann F, Zhang Y, Sun HW, Hayes E, Mikami Y, Jiang K, Davis FP, Kanno Y, Milner JD, Siegel R, et al. Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology. Immunity. 50: 106-120.e10. PMID 30650370 DOI: 10.1016/j.immuni.2018.12.014  0.489
2019 Göschl L, Saferding V, Boucheron N, Backlund J, Platzer A, Hirahara K, Shih H, Matthias P, Scheinecker C, Steiner G, Ellmeier W, Bonelli M. Op0194 Histone Deacetylase 1 (Hdac1): A Key Mediator Of T Cells For The Pathogenesis Of Rheumatoid Arthritis Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2019-Eular.5619  0.364
2018 Harrison OJ, Linehan JL, Shih HY, Bouladoux N, Han SJ, Smelkinson M, Sen SK, Byrd AL, Enamorado M, Yao C, Tamoutounour S, Van Laethem F, Hurabielle C, Collins N, Paun A, et al. Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury. Science (New York, N.Y.). PMID 30523076 DOI: 10.1126/Science.Aat6280  0.568
2018 Povoleri GAM, Nova-Lamperti E, Scottà C, Fanelli G, Chen YC, Becker PD, Boardman D, Costantini B, Romano M, Pavlidis P, McGregor R, Pantazi E, Chauss D, Sun HW, Shih HY, et al. Human retinoic acid-regulated CD161 regulatory T cells support wound repair in intestinal mucosa. Nature Immunology. PMID 30397350 DOI: 10.1038/S41590-018-0230-Z  0.424
2018 Loguercio S, Barajas-Mora EM, Shih HY, Krangel MS, Feeney AJ. Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci. Frontiers in Immunology. 9: 425. PMID 29593713 DOI: 10.3389/Fimmu.2018.00425  0.633
2018 Mikami Y, Scarno G, Zitti B, Shih HY, Kanno Y, Santoni A, O'Shea JJ, Sciumè G. NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice. European Journal of Immunology. PMID 29524223 DOI: 10.1002/eji.201847480  0.544
2017 Sciumè G, Shih HY, Mikami Y, O'Shea JJ. Epigenomic Views of Innate Lymphoid Cells. Frontiers in Immunology. 8: 1579. PMID 29250060 DOI: 10.3389/fimmu.2017.01579  0.578
2017 Iwata S, Mikami Y, Sun HW, Brooks SR, Jankovic D, Hirahara K, Onodera A, Shih HY, Kawabe T, Jiang K, Nakayama T, Sher A, O'Shea JJ, Davis FP, Kanno Y. The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells. Immunity. PMID 28623086 DOI: 10.1016/J.Immuni.2017.05.005  0.562
2016 Roychoudhuri R, Clever D, Li P, Wakabayashi Y, Quinn KM, Klebanoff CA, Ji Y, Sukumar M, Eil RL, Yu Z, Spolski R, Palmer DC, Pan JH, Patel SJ, Macallan DC, ... ... Shih HY, et al. BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers. Nature Immunology. PMID 27158840 DOI: 10.1038/Ni.3441  0.6
2016 Shih HY, Sciumè G, Mikami Y, Guo L, Sun HW, Brooks SR, Urban JF, Davis FP, Kanno Y, O'Shea JJ. Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality. Cell. PMID 27156451 DOI: 10.1016/j.cell.2016.04.029  0.598
2016 Villarino A, Laurence A, Robinson GW, Bonelli M, Dema B, Afzali B, Shih HY, Sun HW, Brooks SR, Hennighausen L, Kanno Y, O'Shea JJ. Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions. Elife. 5. PMID 26999798 DOI: 10.7554/Elife.08384  0.578
2016 Dell'Orso S, Wang AH, Shih HY, Saso K, Berghella L, Gutierrez-Cruz G, Ladurner AG, O'Shea JJ, Sartorelli V, Zare H. The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1. Cell Reports. PMID 26832413 DOI: 10.1016/J.Celrep.2015.12.103  0.521
2016 Villarino A, Laurence A, Robinson GW, Bonelli M, Dema B, Afzali B, Shih H, Sun H, Brooks SR, Hennighausen L, Kanno Y, O'Shea JJ. Author response: Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions Elife. DOI: 10.7554/Elife.08384.034  0.393
2015 Chen L, Carico Z, Shih HY, Krangel MS. A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires. Nature Immunology. 16: 1085-93. PMID 26258942 DOI: 10.1038/Ni.3232  0.643
2015 Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A, Sun HW, Brooks SR, Vahedi G, Shih HY, Gutierrez-Cruz G, Iwata S, Suzuki R, Mikami Y, Okamoto Y, et al. Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity. Immunity. 42: 877-89. PMID 25992861 DOI: 10.1016/J.Immuni.2015.04.014  0.578
2015 Boudil A, Matei IR, Shih HY, Bogdanoski G, Yuan JS, Chang SG, Montpellier B, Kowalski PE, Voisin V, Bashir S, Bader GD, Krangel MS, Guidos CJ. IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection. Nature Immunology. 16: 397-405. PMID 25729925 DOI: 10.1038/Ni.3122  0.591
2015 Chen L, Carico Z, Shih HY, Krangel MS. A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires Nature Immunology. DOI: 10.1038/ni.3232  0.554
2014 Shih HY, Sciumè G, Poholek AC, Vahedi G, Hirahara K, Villarino AV, Bonelli M, Bosselut R, Kanno Y, Muljo SA, O'Shea JJ. Transcriptional and epigenetic networks of helper T and innate lymphoid cells. Immunological Reviews. 261: 23-49. PMID 25123275 DOI: 10.1111/Imr.12208  0.623
2014 Bonelli M, Shih HY, Hirahara K, Singelton K, Laurence A, Poholek A, Hand T, Mikami Y, Vahedi G, Kanno Y, O'Shea JJ. Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes. Current Topics in Microbiology and Immunology. 381: 279-326. PMID 24831346 DOI: 10.1007/82_2014_371  0.6
2013 Shih HY, Krangel MS. Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci. Journal of Immunology (Baltimore, Md. : 1950). 190: 4915-21. PMID 23645930 DOI: 10.4049/Jimmunol.1300218  0.614
2012 Shih HY, Verma-Gaur J, Torkamani A, Feeney AJ, Galjart N, Krangel MS. Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. Proceedings of the National Academy of Sciences of the United States of America. 109: E3493-502. PMID 23169622 DOI: 10.1073/Pnas.1214131109  0.582
2011 Kondilis-Mangum HD, Shih HY, Mahowald G, Sleckman BP, Krangel MS. Regulation of TCRβ allelic exclusion by gene segment proximity and accessibility. Journal of Immunology (Baltimore, Md. : 1950). 187: 6374-81. PMID 22079986 DOI: 10.4049/Jimmunol.1102611  0.651
2011 Shih HY, Hao B, Krangel MS. Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization. Immunologic Research. 49: 192-201. PMID 21128009 DOI: 10.1007/S12026-010-8181-Y  0.626
2010 Shih HY, Krangel MS. Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination. The Journal of Experimental Medicine. 207: 1835-41. PMID 20696701 DOI: 10.1084/Jem.20100772  0.616
2009 Ko T, Shih H, Wei C, Chung W, Hung S, Chen Y. S.9. Genome-Wide Association Studies and the Selective T Cell Receptor (TCR) Usage of CD8+T Cells in Patients with Carbamazepine-Induced Stevens-Johnson Syndrome Clinical Immunology. 131: S135. DOI: 10.1016/J.Clim.2009.03.397  0.385
Low-probability matches (unlikely to be authored by this person)
2023 Fernando N, Gopalakrishnan J, Behensky A, Reich L, Liu C, Bass V, Bono M, Montgomery W, De Pace R, Mattapallil M, Nagarajan V, Brooks S, Maric D, Caspi RR, McGavern DB, ... Shih HY, et al. Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss. Biorxiv : the Preprint Server For Biology. PMID 37090642 DOI: 10.1101/2023.03.18.533293  0.266
2022 Scott-Browne J, Shih HY. Stability and change in epigenetic regulation of immune cells. Immunological Reviews. 305: 5-8. PMID 35034371 DOI: 10.1111/imr.13060  0.222
2021 Censo CD, Marotel M, Mattiola I, Müller L, Scarno G, Pietropaolo G, Peruzzi G, Laffranchi M, Mazej J, Hasim MS, Asif S, Russo E, Tomaipitinca L, Stabile H, Lee SH, ... ... Shih HY, et al. Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver. European Journal of Immunology. PMID 34347289 DOI: 10.1002/eji.202149209  0.216
2018 Rahman MJ, Rodrigues KB, Quiel JA, Liu Y, Bhargava V, Zhao Y, Hotta-Iwamura C, Shih HY, Lau-Kilby AW, Malloy AM, Thoner TW, Tarbell KV. Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice. Jci Insight. 3. PMID 29415894 DOI: 10.1172/Jci.Insight.97843  0.21
2022 Hasim MS, Marotel M, Hodgins JJ, Vulpis E, Makinson OJ, Asif S, Shih HY, Scheer AK, MacMillan O, Alonso FG, Burke KP, Cook DP, Li R, Petrucci MT, Santoni A, et al. When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer. Science Advances. 8: eabj3286. PMID 35417234 DOI: 10.1126/sciadv.abj3286  0.177
2011 Ko TM, Chung WH, Wei CY, Shih HY, Chen JK, Lin CH, Chen YT, Hung SI. Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome. The Journal of Allergy and Clinical Immunology. 128: 1266-1276.e11. PMID 21924464 DOI: 10.1016/j.jaci.2011.08.013  0.162
2021 Lim AI, McFadden T, Link VM, Han SJ, Karlsson RM, Stacy A, Farley TK, Lima-Junior DS, Harrison OJ, Desai JV, Lionakis MS, Shih HY, Cameron HA, Belkaid Y. Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring. Science (New York, N.Y.). 373. PMID 34446580 DOI: 10.1126/science.abf3002  0.135
2006 Hung SI, Chung WH, Jee SH, Chen WC, Chang YT, Lee WR, Hu SL, Wu MT, Chen GS, Wong TW, Hsiao PF, Chen WH, Shih HY, Fang WH, Wei CY, et al. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenetics and Genomics. 16: 297-306. PMID 16538176 DOI: 10.1097/01.fpc.0000199500.46842.4a  0.125
2017 Kobayashi T, Truong A, Shih H, Doebel T, Voisin B, Woodring T, Sohn S, Kennedy E, Jo J, Moro K, Leonard W, Kong H, Nagao K. 604 Spatial heterogeneity and functional diversity of innate lymphoid cells in the skin Journal of Investigative Dermatology. 137: S104. DOI: 10.1016/j.jid.2017.02.626  0.116
2022 Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W, Perner SP, Kanellopoulou C, Park AY, Jiang P, Li J, Baris S, Aydiner EK, ... ... Shih HY, et al. Mucus sialylation determines intestinal host-commensal homeostasis. Cell. PMID 35303419 DOI: 10.1016/j.cell.2022.02.013  0.115
2021 Wu W, Hill SE, Nathan WJ, Paiano J, Callen E, Wang D, Shinoda K, van Wietmarschen N, Colón-Mercado JM, Zong D, De Pace R, Shih HY, Coon S, Parsadanian M, Pavani R, et al. Neuronal enhancers are hotspots for DNA single-strand break repair. Nature. PMID 33767446 DOI: 10.1038/s41586-021-03468-5  0.078
2012 Shih HY, Cheng SH, Lian JK, Lin TY, Chen YF. Light-emitting devices with tunable color from ZnO nanorods grown on InGaN/GaN multiple quantum wells. Optics Express. 20: A270-7. PMID 22418676  0.011
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