Ian G. Macara - Publications

University of Virginia, Charlottesville, VA 
Microbiology Biology, Cell Biology

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Huo Y, Su T, Cai Q, Macara IG. An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter. Cell Reports. PMID 27239038 DOI: 10.1016/J.Celrep.2016.05.011  1
2016 Ahmed SM, Macara IG. Mechanisms of polarity protein expression control. Current Opinion in Cell Biology. 42: 38-45. PMID 27092866 DOI: 10.1016/J.Ceb.2016.04.002  1
2015 Richardson GM, Lannigan J, Macara IG. Does FACS perturb gene expression? Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 87: 166-75. PMID 25598345 DOI: 10.1002/Cyto.A.22608  1
2014 Macara IG, Guyer R, Richardson G, Huo Y, Ahmed SM. Epithelial homeostasis. Current Biology : Cb. 24: R815-25. PMID 25202877 DOI: 10.1016/j.cub.2014.06.068  1
2014 Huo Y, Macara IG. The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance. Nature Cell Biology. 16: 529-37. PMID 24859006 DOI: 10.1038/Ncb2969  1
2014 Andreeva A, Lee J, Lohia M, Wu X, Macara IG, Lu X. PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity. Developmental Cell. 29: 20-33. PMID 24703874 DOI: 10.1016/J.Devcel.2014.02.008  0.52
2014 Rodriguez-Boulan E, Macara IG. Organization and execution of the epithelial polarity programme. Nature Reviews. Molecular Cell Biology. 15: 225-42. PMID 24651541 DOI: 10.1038/Nrm3775  1
2013 Yasuda K, Zhang H, Loiselle D, Haystead T, Macara IG, Mili S. The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules. The Journal of Cell Biology. 203: 737-46. PMID 24297750 DOI: 10.1083/Jcb.201306058  1
2013 Petkowski JJ, Bonsignore LA, Tooley JG, Wilkey DW, Merchant ML, Macara IG, Schaner Tooley CE. NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1. The Biochemical Journal. 456: 453-62. PMID 24090352 DOI: 10.1042/Bj20131163  1
2013 Bailey AO, Panchenko T, Sathyan KM, Petkowski JJ, Pai PJ, Bai DL, Russell DH, Macara IG, Shabanowitz J, Hunt DF, Black BE, Foltz DR. Posttranslational modification of CENP-A influences the conformation of centromeric chromatin. Proceedings of the National Academy of Sciences of the United States of America. 110: 11827-32. PMID 23818633 DOI: 10.1073/Pnas.1300325110  1
2012 Lohia M, Qin Y, Macara IG. The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi. Plos One. 7: e51130. PMID 23226478 DOI: 10.1371/Journal.Pone.0051130  0.52
2012 McCaffrey LM, Montalbano J, Mihai C, Macara IG. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell. 22: 601-14. PMID 23153534 DOI: 10.1016/J.Ccr.2012.10.003  1
2012 Petkowski JJ, Schaner Tooley CE, Anderson LC, Shumilin IA, Balsbaugh JL, Shabanowitz J, Hunt DF, Minor W, Macara IG. Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT. Biochemistry. 51: 5942-50. PMID 22769851 DOI: 10.1021/Bi300278F  1
2011 Pasic L, Eisinger-Mathason TS, Velayudhan BT, Moskaluk CA, Brenin DR, Macara IG, Lannigan DA. Sustained activation of the HER1-ERK1/2-RSK signaling pathway controls myoepithelial cell fate in human mammary tissue. Genes & Development. 25: 1641-53. PMID 21828273 DOI: 10.1101/Gad.2025611  1
2011 Iioka H, Loiselle D, Haystead TA, Macara IG. Efficient detection of RNA-protein interactions using tethered RNAs. Nucleic Acids Research. 39: e53. PMID 21300640 DOI: 10.1093/Nar/Gkq1316  1
2010 Hao Y, Du Q, Chen X, Zheng Z, Balsbaugh JL, Maitra S, Shabanowitz J, Hunt DF, Macara IG. Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Current Biology : Cb. 20: 1809-18. PMID 20933426 DOI: 10.1016/J.Cub.2010.09.032  1
2010 Tooley CE, Petkowski JJ, Muratore-Schroeder TL, Balsbaugh JL, Shabanowitz J, Sabat M, Minor W, Hunt DF, Macara IG. NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature. 466: 1125-8. PMID 20668449 DOI: 10.1038/Nature09343  1
2010 Qin Y, Meisen WH, Hao Y, Macara IG. Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. The Journal of Cell Biology. 189: 661-9. PMID 20479467 DOI: 10.1083/Jcb.201002097  1
2008 Eisinger-Mathason TS, Andrade J, Groehler AL, Clark DE, Muratore-Schroeder TL, Pasic L, Smith JA, Shabanowitz J, Hunt DF, Macara IG, Lannigan DA. Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Molecular Cell. 31: 722-36. PMID 18775331 DOI: 10.1016/J.Molcel.2008.06.025  1
2008 Hao Y, Macara IG. Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1. The Journal of Cell Biology. 182: 827-36. PMID 18762580 DOI: 10.1083/Jcb.200803110  1
2008 Dorfman J, Macara IG. STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Molecular Biology of the Cell. 19: 1614-26. PMID 18256292 DOI: 10.1091/Mbc.E07-05-0454  1
2008 Kremer BE, Macara IG. Septin-Interacting Proteins in Mammals The Septins. 211-228. DOI: 10.1002/9780470779705.ch9  1
2007 Goldstein B, Macara IG. The PAR proteins: fundamental players in animal cell polarization. Developmental Cell. 13: 609-22. PMID 17981131 DOI: 10.1016/J.Devcel.2007.10.007  1
2007 Kremer BE, Adang LA, Macara IG. Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell. 130: 837-50. PMID 17803907 DOI: 10.1016/J.Cell.2007.06.053  1
2007 Capaldo CT, Macara IG. Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Molecular Biology of the Cell. 18: 189-200. PMID 17093058 DOI: 10.1091/Mbc.E06-05-0471  0.76
2006 McNeil E, Capaldo CT, Macara IG. Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells. Molecular Biology of the Cell. 17: 1922-32. PMID 16436508 DOI: 10.1091/Mbc.E05-07-0650  0.76
2005 Qin Y, Capaldo C, Gumbiner BM, Macara IG. The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. The Journal of Cell Biology. 171: 1061-71. PMID 16344308 DOI: 10.1083/Jcb.200506094  1
2005 Sans N, Wang PY, Du Q, Petralia RS, Wang YX, Nakka S, Blumer JB, Macara IG, Wenthold RJ. mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. Nature Cell Biology. 7: 1179-90. PMID 16299499 DOI: 10.1038/Ncb1325  1
2005 Kremer BE, Haystead T, Macara IG. Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Molecular Biology of the Cell. 16: 4648-59. PMID 16093351 DOI: 10.1091/Mbc.E05-03-0267  1
2005 Yi R, Doehle BP, Qin Y, Macara IG, Cullen BR. Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. Rna (New York, N.Y.). 11: 220-6. PMID 15613540 DOI: 10.1261/Rna.7233305  1
2004 Kisurina-Evgenieva O, Mack G, Du Q, Macara I, Khodjakov A, Compton DA. Multiple mechanisms regulate NuMA dynamics at spindle poles. Journal of Cell Science. 117: 6391-400. PMID 15561764 DOI: 10.1242/Jcs.01568  1
2004 Macchi P, Brownawell AM, Grunewald B, DesGroseillers L, Macara IG, Kiebler MA. The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export. The Journal of Biological Chemistry. 279: 31440-4. PMID 15166236 DOI: 10.1074/Jbc.C400226200  1
2003 Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Development. 17: 3011-6. PMID 14681208 DOI: 10.1101/Gad.1158803  1
2003 Slepchenko BM, Schaff JC, Macara I, Loew LM. Quantitative cell biology with the Virtual Cell. Trends in Cell Biology. 13: 570-6. PMID 14573350 DOI: 10.1016/J.Tcb.2003.09.002  1
2003 Xiao Z, Brownawell AM, Macara IG, Lodish HF. A Novel Nuclear Export Signal in Smad1 Is Essential for Its Signaling Activity Journal of Biological Chemistry. 278: 34245-34252. PMID 12821673 DOI: 10.1074/Jbc.M301596200  1
2003 Garrard SM, Capaldo CT, Gao L, Rosen MK, Macara IG, Tomchick DR. Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6. The Embo Journal. 22: 1125-33. PMID 12606577 DOI: 10.1093/Emboj/Cdg110  0.76
2003 Narayanan A, Eifert J, Marfatia KA, Macara IG, Corbett AH, Terns RM, Terns MP. Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolus. Journal of Cell Science. 116: 177-86. PMID 12456727 DOI: 10.1242/Jcs.00176  1
2003 Sheffield PJ, Oliver CJ, Kremer BE, Sheng S, Shao Z, Macara IG. Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments. The Journal of Biological Chemistry. 278: 3483-8. PMID 12446710 DOI: 10.1074/Jbc.M209701200  0.68
2002 Macara IG, Baldarelli R, Field CM, Glotzer M, Hayashi Y, Hsu SC, Kennedy MB, Kinoshita M, Longtine M, Low C, Maltais LJ, McKenzie L, Mitchison TJ, Nishikawa T, Noda M, et al. Mammalian septins nomenclature. Molecular Biology of the Cell. 13: 4111-3. PMID 12475938 DOI: 10.1091/Mbc.E02-07-0438  1
2002 Du Q, Taylor L, Compton DA, Macara IG. LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Current Biology : Cb. 12: 1928-33. PMID 12445386 DOI: 10.1016/S0960-9822(02)01298-8  1
2002 Lindsay ME, Plafker K, Smith AE, Clurman BE, Macara IG. Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Cell. 110: 349-60. PMID 12176322 DOI: 10.1016/S0092-8674(02)00836-X  1
2002 Brugnera E, Haney L, Grimsley C, Lu M, Walk SF, Tosello-Trampont AC, Macara IG, Madhani H, Fink GR, Ravichandran KS. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nature Cell Biology. 4: 574-82. PMID 12134158 DOI: 10.1038/Ncb824  1
2002 Brownawell AM, Holaska JM, Macara IG, Paschal BM. The use of permeabilized cell systems to study nuclear transport. Methods in Molecular Biology (Clifton, N.J.). 189: 209-29. PMID 12094589 DOI: 10.1385/1-59259-281-3:209  1
2002 Nemergut ME, Lindsay ME, Brownawell AM, Macara IG. Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. The Journal of Biological Chemistry. 277: 17385-8. PMID 11932251 DOI: 10.1074/Jbc.C100620200  1
2002 Smith AE, Slepchenko BM, Schaff JC, Loew LM, Macara IG. Systems analysis of Ran transport. Science (New York, N.Y.). 295: 488-91. PMID 11799242 DOI: 10.1126/Science.1064732  1
2001 Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107: 27-41. PMID 11595183 DOI: 10.1016/S0092-8674(01)00520-7  1
2001 Joberty G, Perlungher RR, Sheffield PJ, Kinoshita M, Noda M, Haystead T, Macara IG. Borg proteins control septin organization and are negatively regulated by Cdc42 Nature Cell Biology. 3: 861-866. PMID 11584266 DOI: 10.1038/Ncb1001-861  1
2001 Watson RT, Shigematsu S, Chiang SH, Mora S, Kanzaki M, Macara IG, Saltiel AR, Pessin JE. Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. The Journal of Cell Biology. 154: 829-40. PMID 11502760 DOI: 10.1083/Jcb.200102078  1
2001 Lindsay ME, Holaska JM, Welch K, Paschal BM, Macara IG. Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export. The Journal of Cell Biology. 153: 1391-402. PMID 11425870 DOI: 10.1083/Jcb.153.7.1391  1
2001 Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG. Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B Science. 292: 1540-1543. PMID 11375490 DOI: 10.1126/Science.292.5521.1540  1
2001 Chiang SH, Baumann CA, Kanzaki M, Thurmond DC, Watson RT, Neudauer CL, Macara IG, Pessin JE, Saltiel AR. Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature. 410: 944-8. PMID 11309621 DOI: 10.1038/35073608  1
2000 Nemergut ME, Macara IG. Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms. The Journal of Cell Biology. 149: 835-50. PMID 10811825 DOI: 10.1083/Jcb.149.4.835  0.92
2000 Petersen C, Orem N, Trueheart J, Thorner JW, Macara IG. Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1. The Journal of Biological Chemistry. 275: 4081-91. PMID 10660567 DOI: 10.1074/Jbc.275.6.4081  1
1999 Mattingly RR, Saini V, Macara IG. Activation of the Ras-GRF/CDC25Mm exchange factor by lysophosphatidic acid. Cellular Signalling. 11: 603-10. PMID 10433521 DOI: 10.1016/S0898-6568(99)00034-0  1
1999 Chung SH, Joberty G, Gelino EA, Macara IG, Holz RW. Comparison of the effects on secretion in chromaffin and PC12 cells of Rab3 family members and mutants. Evidence that inhibitory effects are independent of direct interaction with Rabphilin3. The Journal of Biological Chemistry. 274: 18113-20. PMID 10364266 DOI: 10.1074/Jbc.274.25.18113  1
1997 Chung SH, Stabila P, Macara IG, Holz RW. Importance of the Rab3a-GTP binding domain for the intracellular stability and function of Rabphilin3a in secretion. Journal of Neurochemistry. 69: 164-73. PMID 9202307 DOI: 10.1046/J.1471-4159.1997.69010164.X  1
1997 Richards SA, Carey KL, Macara IG. Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export. Science (New York, N.Y.). 276: 1842-4. PMID 9188526 DOI: 10.1126/Science.276.5320.1842  1
1996 Richards SA, Lounsbury KM, Carey KL, Macara IG. A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1. The Journal of Cell Biology. 134: 1157-68. PMID 8794858 DOI: 10.1083/JCB.134.5.1157  1
1996 Mattingly RR, Macara IG. Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits. Nature. 382: 268-72. PMID 8717044 DOI: 10.1038/382268a0  1
1996 Carey KL, Richards SA, Lounsbury KM, Macara IG. Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. The Journal of Cell Biology. 133: 985-96. PMID 8655589 DOI: 10.1083/jcb.133.5.985  1
1996 Wilson DJ, Fortner KA, Lynch DH, Mattingly RR, Macara IG, Posada JA, Budd RC. JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. European Journal of Immunology. 26: 989-94. PMID 8647190 DOI: 10.1002/eji.1830260505  1
1996 Macara IG, Lounsbury KM, Richards SA, Mckiernan C, Bar-Sagi D. The Ras superfamily of GTPases Faseb Journal. 10: 625-630. PMID 8621061 DOI: 10.1096/fasebj.10.5.8621061  1
1995 Brondyk WH, McKiernan CJ, Fortner KA, Stabila P, Holz RW, Macara IG. Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A. Molecular and Cellular Biology. 15: 1137-43. PMID 7532276 DOI: 10.1128/MCB.15.3.1137  1
1994 Mattingly RR, Sorisky A, Brann MR, Macara IG. Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain Molecular and Cellular Biology. 14: 7943-7952. PMID 7969134  1
1993 Bielinski DF, Pyun HY, Linko-Stentz K, Macara IG, Fine RE. Ra1 and Rab3a are major GTP-binding proteins of axonal rapid transport and synaptic vesicles and do not redistribute following depolarization stimulated synaptosomal exocytosis Bba - Biomembranes. 1151: 246-256. PMID 8373799 DOI: 10.1016/0005-2736(93)90109-D  1
1991 Han JW, Mccormick F, Macara IG. Regulation of Ras-GAP and the neurofibromatosis-1 gene product by eicosanoids Science. 252: 576-579. PMID 1902323 DOI: 10.1126/Science.1902323  1
1986 Balduzzi PC, Chovav M, Christensen JR, Macara IG. Specific inhibition of tyrosine kinase activity by an antibody to the v-ros oncogene product Journal of Virology. 60: 765-767. PMID 2430110 DOI: 10.1128/JVI.60.2.765-767.1986  1
1984 Macara IG, Marinetti GV, Balduzzi PC. Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 81: 2728-32. PMID 6326140 DOI: 10.1073/PNAS.81.9.2728  1
1982 Dingley AL, Kustin K, Macara IG, Mcleod GC, Roberts MF. Vanadium-containing tunicate blood cells are not highly acidic. Biochimica Et Biophysica Acta. 720: 384-9. PMID 7115777 DOI: 10.1016/0167-4889(82)90116-1  1
1981 Dingley AL, Kustin K, Macara IG, McLeod GC. Accumulation of vanadium by tunicate blood cells occurs via a specific anion transport system Bba - Biomembranes. 649: 493-502. DOI: 10.1016/0005-2736(81)90152-8  1
1980 Macara IG, Kustin K, Cantley LC. Glutathione reduces cytoplasmic vanadate. Mechanism and physiological implications. Biochimica Et Biophysica Acta. 629: 95-106. PMID 6245716 DOI: 10.1016/0304-4165(80)90268-8  1
1979 Macara IG, McLeod GC, Kustin K. Isolation, properties and structural studies on a compound from tunicate blood cells that may be involved in vanadium accumulation. The Biochemical Journal. 181: 457-65. PMID 496893  1
1979 Macara IG, McLeod GC, Kustin K. Tunichromes and metal ion accumulation in tunicate blood cells Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 63: 299-302. DOI: 10.1016/0305-0491(79)90252-9  1
1979 Macara IG, Mcleod GC, Kustin K. Vanadium in tunicates: Oxygen-binding studies Comparative Biochemistry and Physiology -- Part a: Physiology. 62: 821-826. DOI: 10.1016/0300-9629(79)90009-4  1
1974 Hoy TG, Harrison PM, Shabbir M, Macara IG. The release of iron from horse spleen ferritin to 1,10 phenanthroline Biochemical Journal. 137: 67-70. PMID 4856608 DOI: 10.1042/BJ1370067  1
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