Richard Bucala - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Microbiology Biology, Parasitology Biology

271 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Poulsen KL, Fan XD, Kibler CD, Huang E, Wu X, McMullen MR, Leng L, Bucala R, Ventura-Cots M, Argemi J, Bataller R, Nagy LE. Role of MIF in coordinated expression of hepatic chemokines in patients with alcohol-associated hepatitis. Jci Insight. PMID 33945507 DOI: 10.1172/jci.insight.141420  0.44
2021 Yao J, Leng L, Fu W, Li J, Bronner C, Bucala R. ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the , MIF Immune Susceptibility Locus. Arthritis & Rheumatology (Hoboken, N.J.). PMID 33844457 DOI: 10.1002/art.41753  0.44
2021 Harrison DE, Strong R, Reifsnyder P, Kumar N, Fernandez E, Flurkey K, Javors MA, Lopez-Cruzan M, Macchiarini F, Nelson JF, Bitto A, Sindler AL, Cortopassi G, Kavanagh K, Leng L, ... Bucala R, et al. 17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex. Aging Cell. e13328. PMID 33788371 DOI: 10.1111/acel.13328  0.44
2020 Szczęśniak P, Henke T, Fröhlich S, Plessmann U, Urlaub H, Leng L, Bucala R, Grosse R, Meinhardt A, Klug J. Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44. Journal of Cell Science. PMID 33328325 DOI: 10.1242/jcs.217356  0.44
2020 Odio CD, Miller EJ, Sauler M, Leng L, Piecychna M, Drake WP, Bucala R. Macrophage Migration Inhibitory Factor is not Associated with Sarcoidosis Susceptibility or Severity in Whites or Blacks. Sarcoidosis, Vasculitis, and Diffuse Lung Diseases : Official Journal of Wasog. 37: e2020003. PMID 33264374 DOI: 10.36141/svdld.v37i3.9273  0.44
2020 Kontos C, El Bounkari O, Krammer C, Sinitski D, Hille K, Zan C, Yan G, Wang S, Gao Y, Brandhofer M, Megens RTA, Hoffmann A, Pauli J, Asare Y, Gerra S, ... ... Bucala R, et al. Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting. Nature Communications. 11: 5981. PMID 33239628 DOI: 10.1038/s41467-020-19764-z  0.44
2020 Averdunk L, Bernhagen J, Fehnle K, Surowy H, Lüdecke HJ, Mucha S, Meybohm P, Wieczorek D, Leng L, Marx G, Leaf DE, Zarbock A, Zacharowski K, On Behalf Of The RIPHeart Study Collaborators, Bucala R, et al. The () Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery. Journal of Clinical Medicine. 9. PMID 32932965 DOI: 10.3390/Jcm9092936  0.44
2020 Savic LJ, Doemel LA, Schobert IT, Montgomery RR, Joshi N, Walsh JJ, Santana J, Pekurovsky V, Zhang X, Lin M, Adam L, Boustani A, Duncan J, Leng L, Bucala RJ, et al. Molecular MRI of the Immuno-Metabolic Interplay in a Rabbit Liver Tumor Model: A Biomarker for Resistance Mechanisms in Tumor-targeted Therapy? Radiology. 200373. PMID 32633675 DOI: 10.1148/Radiol.2020200373  0.44
2020 Alban TJ, Bayik D, Otvos B, Rabljenovic A, Leng L, Jia-Shiun L, Roversi G, Lauko A, Momin AA, Mohammadi AM, Peereboom DM, Ahluwalia MS, Matsuda K, Yun K, Bucala R, et al. Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression. Frontiers in Immunology. 11: 1191. PMID 32625208 DOI: 10.3389/Fimmu.2020.01191  0.44
2020 Holowka T, Bucala R. Role of Host and Parasite MIF Cytokines during Infection. Tropical Medicine and Infectious Disease. 5. PMID 32244916 DOI: 10.3390/Tropicalmed5010046  1
2020 Kim BS, Tilstam PV, Arnke K, Leng L, Ruhl T, Piecychna M, Schulte W, Sauler M, Frueh FS, Storti G, Lindenblatt N, Giovanoli P, Pallua N, Bernhagen J, Bucala R. Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF-2 in adipose tissue during endotoxemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31961019 DOI: 10.1096/Fj.201901511R  0.44
2020 Leng L, Siu E, Bucala R. Genotyping Two Promoter Polymorphisms in the MIF Gene: A -794 CATT Microsatellite Repeat and a -173 G/C SNP. Methods in Molecular Biology (Clifton, N.J.). 2080: 67-84. PMID 31745872 DOI: 10.1007/978-1-4939-9936-1_7  0.44
2020 Kim S, Wan F, Zhang X, Zhang Y, Ifedigbo E, Leng L, Bucala R, Sauler M, Lee P. MIF‐CD74 Signaling Protects against Endothelial Senescence in Chronic Obstructive Pulmonary Disease The Faseb Journal. 34: 1-1. DOI: 10.1164/Ajrccm-Conference.2020.201.1_Meetingabstracts.A4374  0.44
2019 Reid D, Shenoi S, Singh R, Wang M, Patel V, Das R, Hiramen K, Moosa Y, Eksteen F, Moll AP, Ndung'u T, Kasprowicz V, Leng L, Friedland GH, Bucala R. Low expression alleles and tuberculosis in HIV infected South Africans. Cytokine: X. 1: 100004. PMID 33604547 DOI: 10.1016/j.cytox.2019.100004  0.44
2019 Tu Y, Guo R, Li J, Wang S, Leng L, Deng J, Bucala R, Lu L. MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654. Frontiers in Immunology. 10: 2229. PMID 31608058 DOI: 10.3389/Fimmu.2019.02229  0.44
2019 Tilstam PV, Pantouris G, Corman M, Andreoli M, Mahboubi K, Davis G, Du X, Leng L, Lolis E, Bucala R. A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity. The Journal of Biological Chemistry. PMID 31578280 DOI: 10.1074/Jbc.Ra119.009860  0.44
2019 Huang H, Chen D, Pu J, Yuan A, Fu Q, Li J, Leng L, Bucala R, Ye S, Lu L. The small molecule macrophage migration inhibitory factor antagonist MIF098, inhibits pulmonary hypertension associated with murine SLE. International Immunopharmacology. 76: 105874. PMID 31499270 DOI: 10.1016/J.Intimp.2019.105874  0.44
2019 Ma Y, Su KN, Pfau D, Rao VS, Wu X, Hu X, Leng L, Du X, Piecychna M, Bedi K, Campbell SG, Eichmann A, Testani JM, Margulies KB, Bucala R, et al. Cardiomyocyte d-dopachrome tautomerase protects against heart failure. Jci Insight. 4. PMID 31484822 DOI: 10.1172/Jci.Insight.128900  0.44
2019 Smith CA, Tyrell DJ, Kulkarni UA, Wood S, Leng L, Zemans RL, Bucala R, Goldstein DR. Macrophage migration inhibitory factor enhances influenza-associated mortality in mice. Jci Insight. 4. PMID 31292300 DOI: 10.1172/Jci.Insight.128034  0.44
2019 Ma F, Kouzoukas DE, Meyer-Siegler KL, Hunt DE, Leng L, Bucala R, Vera PL. MIF mediates bladder pain, not inflammation, in cyclophosphamide cystitis. Cytokine: X. 1. PMID 31289792 DOI: 10.1016/j.cytox.2019.100003  0.44
2019 Poulsen KL, McMullen MR, Huang E, Kibler CD, Sheehan M, Leng L, Bucala R, Nagy LE. Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response after Ethanol Feeding in Mice. Alcoholism, Clinical and Experimental Research. PMID 31009094 DOI: 10.1111/Acer.14065  0.44
2019 Kim HK, Garcia AB, Siu E, Tilstam P, Das R, Roberts S, Leng L, Bucala R. Macrophage migration inhibitory factor regulates innate γδ T-cell responses via IL-17 expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802433R. PMID 30817226 DOI: 10.1096/Fj.201802433R  0.44
2019 Zheng J, Guo R, Tang Y, Fu Q, Chen J, Wu L, Leng L, Bucala R, Song Y, Lu L. miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1. Frontiers in Immunology. 10: 158. PMID 30787934 DOI: 10.3389/Fimmu.2019.00158  0.44
2019 Ma F, Meyer-Siegler KL, Leng L, Bucala R, Vera PL. Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain. Neuroscience Letters. PMID 30708129 DOI: 10.1016/J.Neulet.2019.01.046  0.44
2019 Odio CD, Leng L, Siu E, Piecychna M, Galgiani JN, Holland SM, Bucala R. 2598. Macrophage Migration Inhibitory Factor May Contribute to Disseminated Coccidioidomycosis Susceptibility Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz360.2276  0.44
2018 Zhang C, Ramsey C, Berical A, Yu L, Leng L, McGinnis K, Song YS, Michael H, McCormack M, Allore H, Morris A, Crothers K, Bucala R, Lee PJ, Sauler M. A Functional Macrophage Migration Inhibitory Factor (MIF) Promoter Polymorphism is Associated with Reduced Diffusing Capacity. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30520689 DOI: 10.1152/Ajplung.00439.2018  0.44
2018 Bezdek S, Leng L, Busch H, Mousavi S, Rades D, Dahlke M, Zillikens D, Bucala R, Sadik CD. (MIF) Drives Murine Psoriasiform Dermatitis. Frontiers in Immunology. 9: 2262. PMID 30333830 DOI: 10.3389/Fimmu.2018.02262  0.44
2018 Cui D, Peng Y, Zhang C, Li Z, Su Y, Qi Y, Xing M, Li J, Kim GE, Su KN, Xu J, Wang M, Ding W, Piecychna M, Leng L, ... ... Bucala R, et al. Macrophage migration inhibitory factor mediates metabolic dysfunction induced by atypical antipsychotic therapy. The Journal of Clinical Investigation. PMID 30295645 DOI: 10.1172/Jci93090  0.44
2018 Pellowe AS, Sauler M, Hou Y, Merola J, Liu R, Calderon B, Lauridsen HM, Harris MR, Leng L, Zhang Y, Tilstam PV, Pober JS, Bucala R, Lee PJ, Gonzalez AL. Endothelial cell-secreted MIF reduces pericyte contractility and enhances neutrophil extravasation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800480R. PMID 30252532 DOI: 10.1096/Fj.201800480R  0.44
2018 Ma F, Hunt DE, Leng L, Bucala R, Meyer-Siegler KL, Vera PL. Protease activated-receptor 4 activation as a model of persistent bladder pain: Essential role of macrophage migration inhibitory factor and high mobility group box 1. International Journal of Urology : Official Journal of the Japanese Urological Association. PMID 30112848 DOI: 10.1111/Iju.13778  0.44
2018 Shin MS, Kang Y, Wahl ER, Park HJ, Lazova R, Leng L, Mamula M, Krishnaswamy S, Bucala R, Kang I. Macrophage migration inhibitory factor regulates U1-snRNP immune complex mediated activation of the NLRP3 inflammasome. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30009530 DOI: 10.1002/Art.40672  0.44
2018 Baeza Garcia A, Siu E, Sun T, Exler V, Brito L, Hekele A, Otten G, Augustijn K, Janse CJ, Ulmer JB, Bernhagen J, Fikrig E, Geall A, Bucala R. Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection. Nature Communications. 9: 2714. PMID 30006528 DOI: 10.1038/S41467-018-05041-7  0.48
2018 Trifone C, Salido J, Ruiz MJ, Leng L, Quiroga MF, Salomón H, Bucala R, Ghiglione Y, Turk G. Interaction Between Macrophage Migration Inhibitory Factor and CD74 in Human Immunodeficiency Virus Type I Infected Primary Monocyte-Derived Macrophages Triggers the Production of Proinflammatory Mediators and Enhances Infection of Unactivated CD4 T Cells. Frontiers in Immunology. 9: 1494. PMID 29997630 DOI: 10.3389/Fimmu.2018.01494  0.44
2018 Sreih AG, Ezzedine R, Leng L, Fan J, Yao J, Reid D, Piecychna M, Carette S, Cuthbertson D, Dellaripa P, Hoffman GS, Khalidi NA, Koening CL, Langford CA, Mahr A, ... ... Bucala R, et al. Role of macrophage migration inhibitory factor in granulomatosis with polyangiitis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29953750 DOI: 10.1002/Art.40655  0.44
2018 Jose S, Mukherjee A, Abhyankar MM, Leng L, Bucala R, Sharma D, Madan R. Neutralization of macrophage migration inhibitory factor improves host survival after Clostridium difficile infection. Anaerobe. PMID 29944928 DOI: 10.1016/J.Anaerobe.2018.06.014  0.44
2018 Valiño-Rivas L, Cuarental L, Grana O, Bucala R, Leng L, Sanz A, Gomez G, Ortiz A, Sanchez-Niño MD. TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells. Plos One. 13: e0199391. PMID 29924850 DOI: 10.1371/Journal.Pone.0199391  0.44
2018 Lipschutz R, Bick J, Nguyen V, Lee M, Leng L, Grigorenko E, Bucala R, Mayes LC, Crowley MJ. Macrophage migration inhibitory factor (MIF) gene is associated with adolescents' cortisol reactivity and anxiety. Psychoneuroendocrinology. 95: 170-178. PMID 29870971 DOI: 10.1016/J.Psyneuen.2018.05.033  0.44
2018 Stoppe C, Averdunk L, Goetzenich A, Soppert J, Marlier A, Kraemer S, Vieten J, Coburn M, Kowark A, Kim BS, Marx G, Rex S, Ochi A, Leng L, Moeckel G, ... ... Bucala R, et al. The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery. Science Translational Medicine. 10. PMID 29769287 DOI: 10.1126/Scitranslmed.Aan4886  0.44
2018 Pantouris G, Ho J, Shah D, Syed MA, Leng L, Bhandari V, Bucala R, Batista VS, Loria JP, Lolis E. Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angewandte Chemie (International Ed. in English). PMID 29669180 DOI: 10.2210/Pdb6Bg6/Pdb  0.44
2017 You S, Koh JH, Leng L, Kim WU, Bucala R. The Tumor-like Phenotype of Rheumatoid Synovium: Molecular Profiling and Prospects for Precision Medicine. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29287304 DOI: 10.1002/Art.40406  0.44
2017 Ma F, Kouzoukas DE, Meyer-Siegler KL, Hunt DE, Leng L, Bucala R, Vera PL. Macrophage migration inhibitory factor mediates protease-activated receptor 4-induced bladder pain through urothelial high mobility group box 1. Physiological Reports. 5. PMID 29263120 DOI: 10.14814/Phy2.13549  0.44
2017 Benedek G, Meza-Romero R, Jordan K, Zhang Y, Nguyen H, Kent G, Li J, Siu E, Frazer J, Piecychna M, Du X, Sreih A, Leng L, Wiedrick J, Caillier SJ, ... ... Bucala R, et al. MIF and D-DT are potential disease severity modifiers in male MS subjects. Proceedings of the National Academy of Sciences of the United States of America. PMID 28923927 DOI: 10.1073/Pnas.1712288114  0.44
2017 Djudjaj S, Martin IV, Buhl EM, Nothofer NJ, Leng L, Piecychna M, Floege J, Bernhagen J, Bucala R, Boor P. Macrophage Migration Inhibitory Factor Limits Renal Inflammation and Fibrosis by Counteracting Tubular Cell Cycle Arrest. Journal of the American Society of Nephrology : Jasn. PMID 28801314 DOI: 10.1681/Asn.2017020190  0.44
2017 Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, et al. Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation potentially contributing to cystic fibrosis pathogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28768722 DOI: 10.1096/Fj.201700463R  0.44
2017 Tilstam PV, Qi D, Leng L, Young L, Bucala R. MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics. Expert Opinion On Therapeutic Targets. PMID 28562118 DOI: 10.1080/14728222.2017.1336227  0.44
2017 Ochi A, Chen D, Schulte W, Leng L, Moeckel NG, Piecychna M, Averdunk L, Stoppe C, Bucala R, Moeckel GW. MIF-2/D-DT Enhances Proximal Tubular Cell Regeneration Through SLPI and ATF4-dependent Mechanisms. American Journal of Physiology. Renal Physiology. ajprenal.00683.2016. PMID 28539339 DOI: 10.1152/Ajprenal.00683.2016  0.44
2017 Roger T, Schlapbach LJ, Schneider A, Weier M, Wellmann S, Marquis P, Vermijlen D, Sweep FC, Leng L, Bucala R, Calandra T, Giannoni E. Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early Life. Frontiers in Immunology. 8: 26. PMID 28179905 DOI: 10.3389/fimmu.2017.00026  0.44
2016 Yoo SA, Leng L, Kim BJ, Du X, Tilstam PV, Kim KH, Kong JS, Yoon HJ, Liu A, Wang T, Song Y, Sauler M, Bernhagen J, Ritchlin CT, Lee P, ... ... Bucala R, et al. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872288 DOI: 10.1073/Pnas.1612717113  0.44
2016 Assis DN, Takahashi H, Leng L, Zeniya M, Boyer JL, Bucala R. A Macrophage Migration Inhibitory Factor Polymorphism Is Associated with Autoimmune Hepatitis Severity in US and Japanese Patients. Digestive Diseases and Sciences. PMID 27696094 DOI: 10.1007/S10620-016-4322-Z  0.44
2016 Stijlemans B, Brys L, Korf H, Bieniasz-Krzywiec P, Sparkes A, Vansintjan L, Leng L, Vanbekbergen N, Mazzone M, Caljon G, Van Den Abbeele J, Odongo S, De Trez C, Magez S, Van Ginderachter JA, ... ... Bucala R, et al. MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis. Plos Pathogens. 12: e1005862. PMID 27632207 DOI: 10.1371/Journal.Ppat.1005862  0.44
2016 Kim BS, Tilstam PV, Hwang SS, Simons D, Schulte W, Leng L, Sauler M, Ganse B, Averdunk L, Kopp R, Stoppe C, Bernhagen J, Pallua N, Bucala R. D-dopachrome tautomerase in adipose tissue inflammation and wound repair. Journal of Cellular and Molecular Medicine. PMID 27605340 DOI: 10.1111/Jcmm.12936  0.44
2016 Meza-Romero R, Benedek G, Jordan K, Leng L, Pantouris G, Lolis E, Bucala R, Vandenbark AA. Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74. Cytokine. 88: 62-70. PMID 27573366 DOI: 10.1016/J.Cyto.2016.08.024  0.44
2016 Rowe MA, Harper LR, McNulty MA, Lau AG, Carlson CS, Leng L, Bucala RJ, Miller RA, Loeser RF. Deletion of Macrophage Migration Inhibitory Factor Reduces Severity of Osteoarthritis in Aged Mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27564840 DOI: 10.1002/Art.39844  0.44
2016 Kim BS, Stoppe C, Grieb G, Leng L, Sauler M, Assis D, Simons D, Boecker AH, Schulte W, Piecychna M, Hager S, Bernhagen J, Pallua N, Bucala R. The clinical significance of the MIF homolog d-dopachrome tautomerase (MIF-2) and its circulating receptor (sCD74) in burn. Burns : Journal of the International Society For Burn Injuries. PMID 27209369 DOI: 10.1016/J.Burns.2016.02.005  0.44
2016 Przybyl L, Haase N, Golic M, Rugor J, Solano ME, Arck PC, Gauster M, Huppertz B, Emontzpohl C, Stoppe C, Bernhagen J, Leng L, Bucala R, Schulz H, Heuser A, et al. CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia. Circulation Research. PMID 27199465 DOI: 10.1161/Circresaha.116.308304  0.44
2016 Holowka T, Castilho TM, Garcia AB, Sun T, McMahon-Pratt D, Bucala R. Leishmania-encoded orthologs of macrophage migration inhibitory factor regulate host immunity to promote parasite persistence. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26956417 DOI: 10.1096/Fj.201500189R  1
2016 Xu X, Pang J, Chen Y, Bucala R, Zhang Y, Ren J. Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation. Scientific Reports. 6: 22488. PMID 26940544 DOI: 10.1038/Srep22488  0.44
2016 Galvão I, Dias AC, Tavares LD, Rodrigues IP, Queiroz-Junior CM, Costa VV, Reis AC, Ribeiro RD, Louzada-Junior P, Souza DG, Leng L, Bucala R, Sousa LP, Bozza MT, Teixeira MM, et al. Macrophage migration inhibitory factor drives neutrophil accumulation by facilitating IL-1β production in a murine model of acute gout. Journal of Leukocyte Biology. PMID 26868525 DOI: 10.1189/Jlb.3Ma0915-418R  0.44
2016 Meza-Romero R, Benedek G, Leng L, Bucala R, Vandenbark AA. Predicted structure of MIF/CD74 and RTL1000/CD74 complexes. Metabolic Brain Disease. 31: 249-55. PMID 26851955 DOI: 10.1007/S11011-016-9798-X  0.44
2016 Yao J, Leng L, Sauler M, Fu W, Zheng J, Zhang Y, Du X, Yu X, Lee P, Bucala R. Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus. The Journal of Clinical Investigation. PMID 26752645 DOI: 10.1172/Jci81937  0.4
2016 Tilstam PV, Leng L, Bernhagen J, Schulte WK, Yu X, Kim B, Sauler M, Bucala R. Unique actions of MIF versus D-DT (MIF-2) on lethal macrophage subsets in sepsis Shock. 45: 243. DOI: 10.1097/Shk.0000000000000630  0.44
2015 Das R, Loughran K, Murchison C, Qian F, Leng L, Song Y, Montgomery RR, Loeb M, Bucala R. Association between high expression macrophage migration inhibitory factor (MIF) alleles and West Nile virus encephalitis. Cytokine. 78: 51-54. PMID 26638028 DOI: 10.1016/J.Cyto.2015.11.021  0.44
2015 Hwang SH, Jung SH, Lee S, Choi S, Yoo SA, Park JH, Hwang D, Shim SC, Sabbagh L, Kim KJ, Park SH, Cho CS, Kim BS, Leng L, Montgomery RR, ... Bucala R, et al. Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26554018 DOI: 10.1073/Pnas.1514152112  0.44
2015 Li SQ, Yu Y, Han JZ, Wang D, Liu J, Qian F, Fan GH, Bucala R, Ye RD. Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer's disease. Journal of Neuroinflammation. 12: 177. PMID 26382037 DOI: 10.1186/S12974-015-0396-3  0.4
2015 Pantouris G, Syed MA, Fan C, Rajasekaran D, Cho TY, Rosenberg EM, Bucala R, Bhandari V, Lolis EJ. An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chemistry & Biology. 22: 1197-205. PMID 26364929 DOI: 10.1016/J.Chembiol.2015.08.006  0.44
2015 Bay-Richter C, Janelidze S, Sauro A, Bucala R, Lipton J, Deierborg T, Brundin L. Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice. Journal of Neuroinflammation. 12: 163. PMID 26338025 DOI: 10.1186/S12974-015-0387-4  0.4
2015 Stoppe C, Rex S, Goetzenich A, Kraemer S, Emontzpohl C, Soppert J, Sun Y, Rossaint R, Lue H, Averdunk L, Huang C, Song Y, Pantouris G, Lolis E, Leng L, ... ... Bucala R, et al. Interaction of MIF family proteins in myocardial ischemia/reperfusion damage and their influence on clinical outcome of cardiac surgery patients. Antioxidants & Redox Signaling. PMID 26234719 DOI: 10.1089/Ars.2014.6243  0.44
2015 Sauler M, Bucala R, Lee PJ. Role of macrophage migration inhibitory factor in age-related lung disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 309: L1-10. PMID 25957294 DOI: 10.1152/Ajplung.00339.2014  0.4
2015 Weiser JN, Roche AM, Hergott CB, LaRose MI, Connolly T, Jorgensen WL, Leng L, Bucala R, Das R. Macrophage Migration Inhibitory Factor Is Detrimental in Pneumococcal Pneumonia and a Target for Therapeutic Immunomodulation. The Journal of Infectious Diseases. PMID 25943202 DOI: 10.1093/Infdis/Jiv262  0.44
2015 McDevitt MA, Xie J, Ganapathy-Kanniappan S, Griffith J, Liu A, McDonald C, Thuma P, Gordeuk VR, Metz CN, Mitchell R, Keefer J, David J, Leng L, Bucala R. A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. The Journal of Experimental Medicine. 212: 825. PMID 25941322 DOI: 10.1084/Jem.2005239804172015C  0.44
2015 de Souza HS, Tortori CA, Lintomen L, Figueiredo RT, Bernardazzi C, Leng L, Bucala R, Madi K, Buongusto F, Elia CC, Castelo-Branco MT, Bozza MT. Macrophage migration inhibitory factor promotes eosinophil accumulation and tissue remodeling in eosinophilic esophagitis. Mucosal Immunology. PMID 25712805 DOI: 10.1038/Mi.2015.6  0.44
2015 Gu R, Santos LL, Ngo D, Fan H, Singh PP, Fingerle-Rowson G, Bucala R, Xu J, Quinn JM, Morand EF. Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis. Cytokine. 72: 135-45. PMID 25647268 DOI: 10.1016/J.Cyto.2014.11.015  0.4
2015 Sauler M, Zhang Y, Min JN, Leng L, Shan P, Roberts S, Jorgensen WL, Bucala R, Lee PJ. Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1940-9. PMID 25609432 DOI: 10.1096/Fj.14-260299  0.44
2015 Wu B, Song Y, Leng L, Bucala R, Lu LJ. Treatment of moderate rheumatoid arthritis with different strategies in a health resource-limited setting: a cost-effectiveness analysis in the era of biosimilars. Clinical and Experimental Rheumatology. 33: 20-6. PMID 25438197  0.44
2015 Barnes MA, McMullen MR, Roychowdhury S, Madhun NZ, Niese K, Olman MA, Stavitsky AB, Bucala R, Nagy LE. Macrophage migration inhibitory factor is required for recruitment of scar-associated macrophages during liver fibrosis. Journal of Leukocyte Biology. 97: 161-9. PMID 25398607 DOI: 10.1189/Jlb.3A0614-280R  0.44
2015 Bick J, Nguyen V, Leng L, Piecychna M, Crowley MJ, Bucala R, Mayes LC, Grigorenko EL. Preliminary associations between childhood neglect, MIF, and cortisol: potential pathways to long-term disease risk. Developmental Psychobiology. 57: 131-9. PMID 25380347 DOI: 10.1002/Dev.21265  0.4
2014 Mawhinney L, Armstrong ME, O' Reilly C, Bucala R, Leng L, Fingerle-Rowson G, Fayne D, Keane MP, Tynan A, Maher L, Cooke G, Lloyd D, Conroy H, Donnelly SC. Macrophage migration inhibitory factor (MIF) enzymatic activity and lung cancer. Molecular Medicine (Cambridge, Mass.). 20: 729-35. PMID 25826675 DOI: 10.2119/Molmed.2014.00136  0.44
2014 Pantouris G, Rajasekaran D, Garcia AB, Ruiz VG, Leng L, Jorgensen WL, Bucala R, Lolis EJ. Crystallographic and receptor binding characterization of Plasmodium falciparum macrophage migration inhibitory factor complexed to two potent inhibitors. Journal of Medicinal Chemistry. 57: 8652-6. PMID 25268646 DOI: 10.1021/Jm501168Q  0.4
2014 Stijlemans B, Leng L, Brys L, Sparkes A, Vansintjan L, Caljon G, Raes G, Van Den Abbeele J, Van Ginderachter JA, Beschin A, Bucala R, De Baetselier P. MIF contributes to Trypanosoma brucei associated immunopathogenicity development. Plos Pathogens. 10: e1004414. PMID 25255103 DOI: 10.1371/Journal.Ppat.1004414  0.4
2014 Heinrichs D, Berres ML, Coeuru M, Knauel M, Nellen A, Fischer P, Philippeit C, Bucala R, Trautwein C, Wasmuth HE, Bernhagen J. Protective role of macrophage migration inhibitory factor in nonalcoholic steatohepatitis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 5136-47. PMID 25122558 DOI: 10.1096/Fj.14-256776  0.4
2014 Rajasekaran D, Zierow S, Syed M, Bucala R, Bhandari V, Lolis EJ. Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4961-71. PMID 25016026 DOI: 10.1096/Fj.14-256636  0.4
2014 Qi D, Atsina K, Qu L, Hu X, Wu X, Xu B, Piecychna M, Leng L, Fingerle-Rowson G, Zhang J, Bucala R, Young LH. The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury. The Journal of Clinical Investigation. 124: 3540-50. PMID 24983315 DOI: 10.1172/Jci73061  0.4
2014 Das R, LaRose MI, Hergott CB, Leng L, Bucala R, Weiser JN. Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization. Journal of Immunology (Baltimore, Md. : 1950). 193: 764-72. PMID 24928996 DOI: 10.4049/Jimmunol.1400133  0.4
2014 Wang SL, Wu B, Zhu LA, Leng L, Bucala R, Lu LJ. Construct and criterion validity of the Euro Qol-5D in patients with systemic lupus erythematosus. Plos One. 9: e98883. PMID 24892282 DOI: 10.1371/Journal.Pone.0098883  0.4
2014 Song Y, Zhu LA, Wang SL, Leng L, Bucala R, Lu LJ. Multi-dimensional health assessment questionnaire in China: reliability, validity and clinical value in patients with rheumatoid arthritis. Plos One. 9: e97952. PMID 24848431 DOI: 10.1371/Journal.Pone.0097952  0.4
2014 Meza-Romero R, Benedek G, Yu X, Mooney JL, Dahan R, Duvshani N, Bucala R, Offner H, Reiter Y, Burrows GG, Vandenbark AA. HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 4164-73. PMID 24683185 DOI: 10.4049/Jimmunol.1303118  0.4
2014 Qu G, Fetterer R, Leng L, Du X, Zarlenga D, Shen Z, Han W, Bucala R, Tuo W. Ostertagia ostertagi macrophage migration inhibitory factor is present in all developmental stages and may cross-regulate host functions through interaction with the host receptor. International Journal For Parasitology. 44: 355-67. PMID 24583184 DOI: 10.1016/J.Ijpara.2014.01.009  0.4
2014 White DA, Su Y, Kanellakis P, Kiriazis H, Morand EF, Bucala R, Dart AM, Gao XM, Du XJ. Differential roles of cardiac and leukocyte derived macrophage migration inhibitory factor in inflammatory responses and cardiac remodelling post myocardial infarction. Journal of Molecular and Cellular Cardiology. 69: 32-42. PMID 24508700 DOI: 10.1016/J.Yjmcc.2014.01.015  0.4
2014 Fallica J, Boyer L, Kim B, Serebreni L, Varela L, Hamdan O, Wang L, Simms T, Damarla M, Kolb TM, Bucala R, Mitzner W, Hassoun PM, Damico R. Macrophage migration inhibitory factor is a novel determinant of cigarette smoke-induced lung damage. American Journal of Respiratory Cell and Molecular Biology. 51: 94-103. PMID 24490973 DOI: 10.1165/Rcmb.2013-0371Oc  0.4
2014 Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl JM, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, ... ... Bucala R, et al. Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium. Cell. 156: 456-68. PMID 24485454 DOI: 10.1016/J.Cell.2014.01.006  0.4
2014 Sauler M, Leng L, Trentalange M, Haslip M, Shan P, Piecychna M, Zhang Y, Andrews N, Mannam P, Allore H, Fried T, Bucala R, Lee PJ. Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L487-96. PMID 24441872 DOI: 10.1152/Ajplung.00284.2013  0.4
2014 Das R, Subrahmanyan L, Yang IV, van Duin D, Levy R, Piecychna M, Leng L, Montgomery RR, Shaw A, Schwartz DA, Bucala R. Functional polymorphisms in the gene encoding macrophage migration inhibitory factor are associated with Gram-negative bacteremia in older adults. The Journal of Infectious Diseases. 209: 764-8. PMID 24158957 DOI: 10.1093/Infdis/Jit571  0.4
2014 Assis DN, Leng L, Du X, Zhang CK, Grieb G, Merk M, Garcia AB, McCrann C, Chapiro J, Meinhardt A, Mizue Y, Nikolic-Paterson DJ, Bernhagen J, Kaplan MM, Zhao H, ... ... Bucala R, et al. The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology (Baltimore, Md.). 59: 580-91. PMID 23913513 DOI: 10.1002/Hep.26664  0.4
2014 Binsky-Ehrenreich I, Marom A, Sobotta MC, Shvidel L, Berrebi A, Hazan-Halevy I, Kay S, Aloshin A, Sagi I, Goldenberg DM, Leng L, Bucala R, Herishanu Y, Haran M, Shachar I. CD84 is a survival receptor for CLL cells Oncogene. 33: 1006-1016. PMID 23435417 DOI: 10.1038/Onc.2013.31  0.4
2013 Herrero LJ, Sheng KC, Jian P, Taylor A, Her Z, Herring BL, Chow A, Leo YS, Hickey MJ, Morand EF, Ng LF, Bucala R, Mahalingam S. Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection. Arthritis and Rheumatism. 65: 2724-36. PMID 23896945 DOI: 10.1002/Art.38090  0.4
2013 Das R, Koo MS, Kim BH, Jacob ST, Subbian S, Yao J, Leng L, Levy R, Murchison C, Burman WJ, Moore CC, Scheld WM, David JR, Kaplan G, MacMicking JD, ... Bucala R, et al. Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 110: E2997-3006. PMID 23882081 DOI: 10.1073/Pnas.1301128110  0.4
2013 Qu G, Fetterer R, Jenkins M, Leng L, Shen Z, Murphy C, Han W, Bucala R, Tuo W. Characterization of Neospora caninum macrophage migration inhibitory factor. Experimental Parasitology. 135: 246-56. PMID 23850997 DOI: 10.1016/J.Exppara.2013.07.001  0.44
2013 Fan C, Rajasekaran D, Syed MA, Leng L, Loria JP, Bhandari V, Bucala R, Lolis EJ. MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations. Proceedings of the National Academy of Sciences of the United States of America. 110: 10994-9. PMID 23776208 DOI: 10.1073/Pnas.1221817110  0.4
2013 Wang J, Tong C, Yan X, Yeung E, Gandavadi S, Hare AA, Du X, Chen Y, Xiong H, Ma C, Leng L, Young LH, Jorgensen WL, Li J, Bucala R. Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction. Circulation. 128: 225-36. PMID 23753877 DOI: 10.1161/Circulationaha.112.000862  0.4
2013 Metodieva G, Nogueira-de-Souza NC, Greenwood C, Al-Janabi K, Leng L, Bucala R, Metodiev MV. CD74-dependent deregulation of the tumor suppressor scribble in human epithelial and breast cancer cells. Neoplasia (New York, N.Y.). 15: 660-8. PMID 23730214 DOI: 10.1593/Neo.13464  0.4
2013 Wang FF, Huang XF, Shen N, Leng L, Bucala R, Chen SL, Lu LJ. A genetic role for macrophage migration inhibitory factor (MIF) in adult-onset Still's disease. Arthritis Research & Therapy. 15: R65. PMID 23721694 DOI: 10.1186/Ar4239  0.44
2013 Wang SL, Wu B, Leng L, Bucala R, Lu LJ. Validity of LupusQoL-China for the assessment of health related quality of life in Chinese patients with systemic lupus erythematosus. Plos One. 8: e63795. PMID 23717486 DOI: 10.1371/Journal.Pone.0063795  0.44
2013 Xu X, Pacheco BD, Leng L, Bucala R, Ren J. Macrophage migration inhibitory factor plays a permissive role in the maintenance of cardiac contractile function under starvation through regulation of autophagy. Cardiovascular Research. 99: 412-21. PMID 23674514 DOI: 10.1093/Cvr/Cvt116  0.44
2013 Sun H, Choo-Wing R, Sureshbabu A, Fan J, Leng L, Yu S, Jiang D, Noble P, Homer RJ, Bucala R, Bhandari V. A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung. Plos One. 8: e60560. PMID 23637753 DOI: 10.1371/Journal.Pone.0060560  0.44
2013 Benedek G, Meza-Romero R, Andrew S, Leng L, Burrows GG, Bourdette D, Offner H, Bucala R, Vandenbark AA. Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects. European Journal of Immunology. 43: 1309-21. PMID 23576302 DOI: 10.1002/Eji.201243162  0.4
2013 Mathew B, Jacobson JR, Siegler JH, Moitra J, Blasco M, Xie L, Unzueta C, Zhou T, Evenoski C, Al-Sakka M, Sharma R, Huey B, Bulent A, Smith B, Jayaraman S, ... ... Bucala R, et al. Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation. American Journal of Respiratory Cell and Molecular Biology. 49: 269-78. PMID 23526214 DOI: 10.1165/Rcmb.2012-0291Oc  0.4
2013 Singh A, Leng L, Fan J, Gajda M, Bräuer R, Fingerle-Rowson G, Bucala R, Illges H. Macrophage-derived, macrophage migration inhibitory factor (MIF) is necessary to induce disease in the K/BxN serum-induced model of arthritis. Rheumatology International. 33: 2301-8. PMID 23503937 DOI: 10.1007/S00296-013-2713-4  0.44
2013 Sun H, Choo-Wing R, Fan J, Leng L, Syed MA, Hare AA, Jorgensen WL, Bucala R, Bhandari V. Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia. Respiratory Research. 14: 27. PMID 23448134 DOI: 10.1186/1465-9921-14-27  0.4
2013 Turtzo LC, Li J, Persky R, Benashski S, Weston G, Bucala R, Venna VR, McCullough LD. Deletion of macrophage migration inhibitory factor worsens stroke outcome in female mice. Neurobiology of Disease. 54: 421-31. PMID 23376686 DOI: 10.1016/J.Nbd.2013.01.016  0.4
2013 Barnes MA, McMullen MR, Roychowdhury S, Pisano SG, Liu X, Stavitsky AB, Bucala R, Nagy LE. Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis. Hepatology (Baltimore, Md.). 57: 1980-91. PMID 23174952 DOI: 10.1002/Hep.26169  0.44
2013 Stoppe C, Werker T, Rossaint R, Dollo F, Lue H, Wonisch W, Menon A, Goetzenich A, Bruells CS, Coburn M, Kopp R, Bucala R, Bernhagen J, Rex S. What is the significance of perioperative release of macrophage migration inhibitory factor in cardiac surgery? Antioxidants & Redox Signaling. 19: 231-9. PMID 23157710 DOI: 10.1089/Ars.2012.5015  0.4
2012 Dahlgren MK, Garcia AB, Hare AA, Tirado-Rives J, Leng L, Bucala R, Jorgensen WL. Virtual screening and optimization yield low-nanomolar inhibitors of the tautomerase activity of Plasmodium falciparum macrophage migration inhibitory factor. Journal of Medicinal Chemistry. 55: 10148-59. PMID 23067344 DOI: 10.1021/Jm301269S  0.4
2012 Choi S, Kim HR, Leng L, Kang I, Jorgensen WL, Cho CS, Bucala R, Kim WU. Role of macrophage migration inhibitory factor in the regulatory T cell response of tumor-bearing mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 3905-13. PMID 22972922 DOI: 10.4049/Jimmunol.1102152  0.4
2012 Russell TM, Herzog EL, Bucala R. Flow cytometric identification of fibrocytes in scleroderma lung disease. Methods in Molecular Biology (Clifton, N.J.). 900: 327-46. PMID 22933077 DOI: 10.1007/978-1-60761-720-4_16  0.4
2012 Bai F, Asojo OA, Cirillo P, Ciustea M, Ledizet M, Aristoff PA, Leng L, Koski RA, Powell TJ, Bucala R, Anthony KG. A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF). The Journal of Biological Chemistry. 287: 30653-63. PMID 22782901 DOI: 10.1074/Jbc.M112.385583  0.4
2012 Sun T, Holowka T, Song Y, Zierow S, Leng L, Chen Y, Xiong H, Griffith J, Nouraie M, Thuma PE, Lolis E, Janse CJ, Gordeuk VR, Augustijn K, Bucala R. A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria. Proceedings of the National Academy of Sciences of the United States of America. 109: E2117-26. PMID 22778413 DOI: 10.1073/Pnas.1206573109  0.4
2012 Adamali H, Armstrong ME, McLaughlin AM, Cooke G, McKone E, Costello CM, Gallagher CG, Leng L, Baugh JA, Fingerle-Rowson G, Bucala RJ, McLoughlin P, Donnelly SC. Macrophage migration inhibitory factor enzymatic activity, lung inflammation, and cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 186: 162-9. PMID 22592805 DOI: 10.1164/rccm.201110-1864OC  0.4
2012 Telang S, Clem BF, Klarer AC, Clem AL, Trent JO, Bucala R, Chesney J. Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation. Journal of Translational Medicine. 10: 95. PMID 22591674 DOI: 10.1186/1479-5876-10-95  0.4
2012 Wang X, Chen T, Leng L, Fan J, Cao K, Duan Z, Zhang X, Shao C, Wu M, Tadmori I, Li T, Liang L, Sun D, Zheng S, Meinhardt A, ... ... Bucala R, et al. MIF produced by bone marrow-derived macrophages contributes to teratoma progression after embryonic stem cell transplantation. Cancer Research. 72: 2867-78. PMID 22461508 DOI: 10.1158/0008-5472.Can-11-3247  0.44
2012 Mount PF, Gleich K, Tam S, Fraser SA, Choy SW, Dwyer KM, Lu B, Denderen BV, Fingerle-Rowson G, Bucala R, Kemp BE, Power DA. The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice. Plos One. 7: e29887. PMID 22253816 DOI: 10.1371/Journal.Pone.0029887  0.4
2012 Teismann P, Sathe K, Bierhaus A, Leng L, Martin HL, Bucala R, Weigle B, Nawroth PP, Schulz JB. Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity. Neurobiology of Aging. 33: 2478-90. PMID 22227007 DOI: 10.1016/J.Neurobiolaging.2011.12.006  0.44
2012 Greenwood C, Metodieva G, Al-Janabi K, Lausen B, Alldridge L, Leng L, Bucala R, Fernandez N, Metodiev MV. Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer. Journal of Proteomics. 75: 3031-40. PMID 22178447 DOI: 10.1016/J.Jprot.2011.11.033  0.44
2012 Cohen S, Shoshana OY, Zelman-Toister E, Maharshak N, Binsky-Ehrenreich I, Gordin M, Hazan-Halevy I, Herishanu Y, Shvidel L, Haran M, Leng L, Bucala R, Harroch S, Shachar I. The cytokine midkine and its receptor RPTPζ regulate B cell survival in a pathway induced by CD74. Journal of Immunology (Baltimore, Md. : 1950). 188: 259-69. PMID 22140262 DOI: 10.4049/Jimmunol.1101468  0.4
2012 Qian F, Wang X, Zhang L, Chen S, Piecychna M, Allore H, Bockenstedt L, Malawista S, Bucala R, Shaw AC, Fikrig E, Montgomery RR. Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly. Aging Cell. 11: 104-10. PMID 22023165 DOI: 10.1111/J.1474-9726.2011.00759.X  0.4
2011 Sreih A, Ezzeddine R, Leng L, LaChance A, Yu G, Mizue Y, Subrahmanyan L, Pons-Estel BA, Abelson AK, Gunnarsson I, Svenungsson E, Cavett J, Glenn S, Zhang L, Montgomery R, ... ... Bucala R, et al. Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus. Arthritis and Rheumatism. 63: 3942-51. PMID 22127710 DOI: 10.1002/Art.30624  0.44
2011 Heinrichs D, Knauel M, Offermanns C, Berres ML, Nellen A, Leng L, Schmitz P, Bucala R, Trautwein C, Weber C, Bernhagen J, Wasmuth HE. Macrophage migration inhibitory factor (MIF) exerts antifibrotic effects in experimental liver fibrosis via CD74. Proceedings of the National Academy of Sciences of the United States of America. 108: 17444-9. PMID 21969590 DOI: 10.1073/Pnas.1107023108  0.4
2011 Cho Y, Vermeire JJ, Merkel JS, Leng L, Du X, Bucala R, Cappello M, Lolis E. Drug repositioning and pharmacophore identification in the discovery of hookworm MIF inhibitors. Chemistry & Biology. 18: 1089-101. PMID 21944748 DOI: 10.1016/J.Chembiol.2011.07.011  0.4
2011 Kim HR, Lee SA, Kim HJ, Kong MH, Kim YR, Kang SH, Lee KH, Leng L, Lee BJ, Park C, Kook Y, Kim B, Bucala R. Elevated Levels of Macrophage Migration Inhibitory Factor in Women with Metabolic Syndrome Hormone and Metabolic Research. 43: 642-645. PMID 21823060 DOI: 10.1055/S-0031-1283150  0.44
2011 Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, Fan J, Lue H, Chen Y, Xiong H, Chagnon F, Bernhagen J, Lolis E, Mor G, Lesur O, ... Bucala R, et al. The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proceedings of the National Academy of Sciences of the United States of America. 108: E577-85. PMID 21817065 DOI: 10.1073/Pnas.1102941108  0.4
2011 Jorgensen WL, Trofimov A, Du X, Hare AA, Leng L, Bucala R. Benzisothiazolones as modulators of macrophage migration inhibitory factor. Bioorganic & Medicinal Chemistry Letters. 21: 4545-9. PMID 21719283 DOI: 10.1016/J.Bmcl.2011.05.127  0.4
2011 Peng X, Mathai SK, Murray LA, Russell T, Reilkoff R, Chen Q, Gulati M, Elias JA, Bucala R, Gan Y, Herzog EL. Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis. Fibrogenesis & Tissue Repair. 4: 12. PMID 21586112 DOI: 10.1186/1755-1536-4-12  0.4
2011 Das R, Moss JE, Robinson E, Roberts S, Levy R, Mizue Y, Leng L, McDonald C, Tigelaar RE, Herrick CA, Bucala R. Role of macrophage migration inhibitory factor in the Th2 immune response to epicutaneous sensitization. Journal of Clinical Immunology. 31: 666-80. PMID 21559932 DOI: 10.1007/S10875-011-9541-7  0.4
2011 Malu DT, Bélanger B, Desautels F, Kelendji K, Dalko E, Sanchez-Dardon J, Leng L, Bucala R, Satoskar AR, Scorza T. Macrophage migration inhibitory factor: a downregulator of early T cell-dependent IFN-gamma responses in Plasmodium chabaudi adami (556 KA)-infected mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 6271-9. PMID 21518974 DOI: 10.4049/Jimmunol.1003355  0.44
2011 Gan Y, Reilkoff R, Peng X, Russell T, Chen Q, Mathai SK, Homer R, Gulati M, Siner J, Elias J, Bucala R, Herzog E. Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease. Arthritis and Rheumatism. 63: 2484-94. PMID 21484765 DOI: 10.1002/Art.30386  0.4
2011 Fan H, Hall P, Santos LL, Gregory JL, Fingerle-Rowson G, Bucala R, Morand EF, Hickey MJ. Macrophage migration inhibitory factor and CD74 regulate macrophage chemotactic responses via MAPK and Rho GTPase. Journal of Immunology (Baltimore, Md. : 1950). 186: 4915-24. PMID 21411731 DOI: 10.4049/Jimmunol.1003713  0.4
2011 Doernberg S, Schaaf B, Dalhoff K, Leng L, Beitin A, Quagliarello V, Bucala R. Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae. Cytokine. 53: 292-294. PMID 21208809 DOI: 10.1016/J.Cyto.2010.12.010  0.44
2011 Leng L, Chen L, Fan J, Greven D, Arjona A, Du X, Austin D, Kashgarian M, Yin Z, Huang XR, Lan HY, Lolis E, Nikolic-Paterson D, Bucala R. A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 527-38. PMID 21106847 DOI: 10.4049/Jimmunol.1001767  0.4
2011 Inácio AR, Ruscher K, Leng L, Bucala R, Deierborg T. Macrophage migration inhibitory factor promotes cell death and aggravates neurologic deficits after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1093-106. PMID 21063426 DOI: 10.1038/Jcbfm.2010.194  0.44
2011 Lue H, Dewor M, Leng L, Bucala R, Bernhagen J. Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74. Cellular Signalling. 23: 135-144. PMID 20807568 DOI: 10.1016/J.Cellsig.2010.08.013  0.44
2011 Lapter S, Ben-David H, Sharabi A, Zinger H, Telerman A, Gordin M, Leng L, Bucala R, Shachar I, Mozes E. A role for the B-cell CD74/macrophage migration inhibitory factor pathway in the immunomodulation of systemic lupus erythematosus by a therapeutic tolerogenic peptide. Immunology. 132: 87-95. PMID 20738420 DOI: 10.1111/J.1365-2567.2010.03342.X  0.4
2011 Tam XHL, Shiu SWM, Leng L, Bucala R, Betteridge DJ, Tan KCB. Enhanced expression of receptor for advanced glycation end-products is associated with low circulating soluble isoforms of the receptor in Type 2 diabetes. Clinical Science. 120: 81-89. PMID 20726839 DOI: 10.1042/Cs20100256  0.44
2011 Heinrichs P, Jung M, Offermanns C, Berres M-, Nellen A, Schmitz P, Leng L, Bucala R, Trautwein C, Weber C, Bernhagen J, Wasmuth HE. 1038 Macrophage Migration Inhibitory Factor (Mif) Acts As An Anti-Fibrotic Cytokine In Experimental Liver Fibrosis Via Cd74 And Ampk Journal of Hepatology. 54. DOI: 10.1016/S0168-8278(11)61040-4  0.44
2010 Jorgensen WL, Gandavadi S, Du X, Hare AA, Trofimov A, Leng L, Bucala R. Receptor agonists of macrophage migration inhibitory factor. Bioorganic & Medicinal Chemistry Letters. 20: 7033-6. PMID 20971005 DOI: 10.1016/J.Bmcl.2010.09.118  0.4
2010 Hare AA, Leng L, Gandavadi S, Du X, Cournia Z, Bucala R, Jorgensen WL. Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF). Bioorganic & Medicinal Chemistry Letters. 20: 5811-4. PMID 20728358 DOI: 10.1016/J.Bmcl.2010.07.129  0.4
2010 Gordin M, Tesio M, Cohen S, Gore Y, Lantner F, Leng L, Bucala R, Shachar I. c-Met and its ligand hepatocyte growth factor/scatter factor regulate mature B cell survival in a pathway induced by CD74. Journal of Immunology (Baltimore, Md. : 1950). 185: 2020-31. PMID 20639480 DOI: 10.4049/Jimmunol.0902566  0.4
2010 Maharshak N, Cohen S, Lantner F, Hart G, Leng L, Bucala R, Shachar I. CD74 is a survival receptor on colon epithelial cells. World Journal of Gastroenterology. 16: 3258-66. PMID 20614481 DOI: 10.3748/Wjg.V16.I26.3258  0.4
2010 Ma H, Wang J, Thomas DP, Tong C, Leng L, Wang W, Merk M, Zierow S, Bernhagen J, Ren J, Bucala R, Li J. Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation. 122: 282-92. PMID 20606117 DOI: 10.1161/Circulationaha.110.953208  0.44
2010 Dunne DW, Shaw A, Bockenstedt LK, Allore HG, Chen S, Malawista SE, Leng L, Mizue Y, Piecychna M, Zhang L, Towle V, Bucala R, Montgomery RR, Fikrig E. Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults. Plos One. 5: e11343. PMID 20596538 DOI: 10.1371/Journal.Pone.0011343  0.4
2010 Traggiai E, Casati A, Frascoli M, Porcellini S, Ponzoni M, Sanvito F, Leng L, Bucala R, Moretta L, Grassi F. Selective preservation of bone marrow mature recirculating but not marginal zone B cells in murine models of chronic inflammation. Plos One. 5. PMID 20582316 DOI: 10.1371/Journal.Pone.0011262  0.44
2010 Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proceedings of the National Academy of Sciences of the United States of America. 107: 11313-8. PMID 20534506 DOI: 10.1073/Pnas.1002716107  0.4
2010 Binsky I, Lantner F, Grabovsky V, Harpaz N, Shvidel L, Berrebi A, Goldenberg DM, Leng L, Bucala R, Alon R, Haran M, Shachar I. TAp63 regulates VLA-4 expression and chronic lymphocytic leukemia cell migration to the bone marrow in a CD74-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 184: 4761-9. PMID 20357260 DOI: 10.4049/Jimmunol.0904149  0.4
2010 Herzog EL, Bucala R. Fibrocytes in health and disease Experimental Hematology. 38: 548-556. PMID 20303382 DOI: 10.1016/J.Exphem.2010.03.004  0.4
2010 Greven D, Leng L, Bucala R. Autoimmune diseases: MIF as a therapeutic target Expert Opinion On Therapeutic Targets. 14: 253-264. PMID 20148714 DOI: 10.1517/14728220903551304  0.4
2010 Regis EG, Barreto-de-Souza V, Morgado MG, Bozza MT, Leng L, Bucala R, Bou-Habib DC. Elevated levels of macrophage migration inhibitory factor (MIF) in the plasma of HIV-1-infected patients and in HIV-1-infected cell cultures: a relevant role on viral replication. Virology. 399: 31-8. PMID 20085845 DOI: 10.1016/J.Virol.2009.12.018  0.44
2009 Vakil V, Sung JJ, Piecychna M, Crawford JR, Kuo P, Abu-Alfa AK, Cowper SE, Bucala R, Gomer RH. Gadolinium-containing magnetic resonance image contrast agent promotes fibrocyte differentiation. Journal of Magnetic Resonance Imaging : Jmri. 30: 1284-8. PMID 19937928 DOI: 10.1002/Jmri.21800  0.4
2009 Qi D, Hu X, Wu X, Merk M, Leng L, Bucala R, Young LH. Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. The Journal of Clinical Investigation. 119: 3807-16. PMID 19920350 DOI: 10.1172/Jci39738  0.4
2009 Griffith JW, Sun T, McIntosh MT, Bucala R. Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. Journal of Immunology (Baltimore, Md. : 1950). 183: 5208-20. PMID 19783673 DOI: 10.4049/Jimmunol.0713552  0.48
2009 Ouertatani-Sakouhi H, El-Turk F, Fauvet B, Roger T, Le Roy D, Karpinar DP, Leng L, Bucala R, Zweckstetter M, Calandra T, Lashuel HA. A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry. 48: 9858-70. PMID 19737008 DOI: 10.1021/Bi900957E  0.4
2009 Leng L, Wang W, Roger T, Merk M, Wuttke M, Calandra T, Bucala R. Glucocorticoid-induced MIF expression by human CEM T cells. Cytokine. 48: 177-85. PMID 19646897 DOI: 10.1016/J.Cyto.2009.07.002  0.4
2009 Awandare GA, Martinson JJ, Were T, Ouma C, Davenport GC, Ong'echa JM, Wang W, Leng L, Ferrell RE, Bucala R, Perkins DJ. MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia. The Journal of Infectious Diseases. 200: 629-37. PMID 19591577 DOI: 10.1086/600894  0.4
2009 Hamasaka A, Abe R, Koyama Y, Yoshioka N, Fujita Y, Hoshina D, Sasaki M, Hirasawa T, Onodera S, Ohshima S, Leng L, Bucala R, Nishihira J, Shimizu T, Shimizu H. DNA vaccination against macrophage migration inhibitory factor improves atopic dermatitis in murine models. The Journal of Allergy and Clinical Immunology. 124: 90-99. PMID 19482347 DOI: 10.1016/J.Jaci.2009.04.025  0.44
2009 Verschuren L, Kooistra T, Bernhagen J, Voshol PJ, Ouwens DM, van Erk M, de Vries-van der Weij J, Leng L, van Bockel JH, van Dijk KW, Fingerle-Rowson G, Bucala R, Kleemann R. MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease. Circulation Research. 105: 99-107. PMID 19478200 DOI: 10.1161/Circresaha.109.199166  0.4
2009 Merk M, Baugh J, Zierow S, Leng L, Pal U, Lee SJ, Ebert AD, Mizue Y, Trent JO, Mitchell R, Nickel W, Kavathas PB, Bernhagen J, Bucala R. The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor. Journal of Immunology (Baltimore, Md. : 1950). 182: 6896-906. PMID 19454686 DOI: 10.4049/Jimmunol.0803710  0.4
2009 Yende S, Angus DC, Kong L, Kellum JA, Weissfeld L, Ferrell R, Finegold D, Carter M, Leng L, Peng ZY, Bucala R. The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumonia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2403-11. PMID 19346297 DOI: 10.1096/Fj.09-129445  0.4
2009 Fingerle-Rowson G, Kaleswarapu DR, Schlander C, Kabgani N, Brocks T, Reinart N, Busch R, Schütz A, Lue H, Du X, Liu A, Xiong H, Chen Y, Nemajerova A, Hallek M, ... ... Bucala R, et al. A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Molecular and Cellular Biology. 29: 1922-32. PMID 19188446 DOI: 10.1128/Mcb.01907-08  0.44
2009 Filip AM, Klug J, Cayli S, Fröhlich S, Henke T, Lacher P, Eickhoff R, Bulau P, Linder M, Carlsson-Skwirut C, Leng L, Bucala R, Kraemer S, Bernhagen J, Meinhardt A. Ribosomal protein S19 interacts with macrophage migration inhibitory factor and attenuates its pro-inflammatory function. The Journal of Biological Chemistry. 284: 7977-85. PMID 19155217 DOI: 10.1074/Jbc.M808620200  0.4
2009 Frascaroli G, Varani S, Blankenhorn N, Pretsch R, Bacher M, Leng L, Bucala R, Landini MP, Mertens T. Human cytomegalovirus paralyzes macrophage motility through down-regulation of chemokine receptors, reorganization of the cytoskeleton, and release of macrophage migration inhibitory factor. Journal of Immunology. 182: 477-488. PMID 19109179 DOI: 10.4049/Jimmunol.182.1.477  0.44
2009 Crichlow GV, Lubetsky JB, Leng L, Bucala R, Lolis EJ. Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry. 48: 132-9. PMID 19090677 DOI: 10.1021/Bi8014423  0.4
2009 Cournia Z, Leng L, Gandavadi S, Du X, Bucala R, Jorgensen WL. Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening. Journal of Medicinal Chemistry. 52: 416-24. PMID 19090668 DOI: 10.1021/Jm801100V  0.4
2009 Shiu SW, Tan KC, Wong Y, Leng L, Bucala R. Glycoxidized LDL increases lectin-like oxidized low density lipoprotein receptor-1 in diabetes mellitus. Atherosclerosis. 203: 522-7. PMID 18755461 DOI: 10.1016/J.Atherosclerosis.2008.07.012  0.44
2009 Ma H, Wang J, Lane E, Leng L, Wang W, Ren J, Bucala R, Li J. MIF-AMPK cascades Nature Precedings. 4: 1-1. DOI: 10.1038/Npre.2009.2466.2  0.44
2008 Bifulco C, McDaniel K, Leng L, Bucala R. Tumor growth-promoting properties of macrophage migration inhibitory factor. Current Pharmaceutical Design. 14: 3790-801. PMID 19128232 DOI: 10.2174/138161208786898608  0.44
2008 El-Turk F, Cascella M, Ouertatani-Sakouhi H, Narayanan RL, Leng L, Bucala R, Zweckstetter M, Rothlisberger U, Lashuel HA. The conformational flexibility of the carboxy terminal residues 105-114 is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry. 47: 10740-56. PMID 18795803 DOI: 10.1021/Bi800603X  0.4
2008 Winner M, Meier J, Zierow S, Rendon BE, Crichlow GV, Riggs R, Bucala R, Leng L, Smith N, Lolis E, Trent JO, Mitchell RA. A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Research. 68: 7253-7. PMID 18794110 DOI: 10.1158/0008-5472.Can-07-6227  0.4
2008 Grigorenko EL, Han SS, Yrigollen CM, Leng L, Mizue Y, Anderson GM, Mulder EJ, de Bildt A, Minderaa RB, Volkmar FR, Chang JT, Bucala R. Macrophage migration inhibitory factor and autism spectrum disorders. Pediatrics. 122: e438-45. PMID 18676531 DOI: 10.1542/Peds.2007-3604  0.4
2008 Flores M, Saavedra R, Bautista R, Viedma R, Tenorio EP, Leng L, Sánchez Y, Juárez I, Satoskar AA, Shenoy AS, Terrazas LI, Bucala R, Barbi J, Satoskar AR, Rodriguez-Sosa M. Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3661-71. PMID 18606868 DOI: 10.1096/Fj.08-111666  0.44
2008 Vermeire JJ, Cho Y, Lolis E, Bucala R, Cappello M. Orthologs of macrophage migration inhibitory factor from parasitic nematodes. Trends in Parasitology. 24: 355-63. PMID 18603473 DOI: 10.1016/J.Pt.2008.04.007  0.4
2008 Kamir D, Zierow S, Leng L, Cho Y, Diaz Y, Griffith J, McDonald C, Merk M, Mitchell RA, Trent J, Chen Y, Kwong YK, Xiong H, Vermeire J, Cappello M, ... ... Bucala R, et al. A Leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses. Journal of Immunology (Baltimore, Md. : 1950). 180: 8250-61. PMID 18523291 DOI: 10.4049/Jimmunol.180.12.8250  0.4
2008 Rittirsch D, Flierl MA, Day DE, Nadeau BA, McGuire SR, Hoesel LM, Ipaktchi K, Zetoune FS, Sarma JV, Leng L, Huber-Lang MS, Neff TA, Bucala R, Ward PA. Acute lung injury induced by lipopolysaccharide is independent of complement activation. Journal of Immunology (Baltimore, Md. : 1950). 180: 7664-72. PMID 18490769 DOI: 10.4049/Jimmunol.180.11.7664  0.4
2008 Tan KC, Shiu SW, Wong Y, Leng L, Bucala R. Soluble lectin-like oxidized low density lipoprotein receptor-1 in type 2 diabetes mellitus. Journal of Lipid Research. 49: 1438-44. PMID 18408244 DOI: 10.1194/Jlr.M700551-Jlr200  0.44
2008 Christian CL, Salmon JE, Bucala R. A time capsule for rheumatology. Arthritis and Rheumatism. 58: S34-8. PMID 18240264 DOI: 10.1002/Art.23189  0.4
2008 Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature. 451: 578-82. PMID 18235500 DOI: 10.1038/Nature06504  0.4
2008 Gore Y, Starlets D, Maharshak N, Becker-Herman S, Kaneyuki U, Leng L, Bucala R, Shachar I. Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. The Journal of Biological Chemistry. 283: 2784-92. PMID 18056708 DOI: 10.1074/Jbc.M703265200  0.4
2008 Ma H, Wang J, Lane E, Leng L, Wang W, Ren J, Bucala R, Li J. Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress Nature Precedings. DOI: 10.1038/Npre.2008.2466.1  0.44
2007 Griffith JW, O'Connor C, Bernard K, Town T, Goldstein DR, Bucala R. Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. The Journal of Infectious Diseases. 196: 1553-64. PMID 18008236 DOI: 10.1086/522865  0.48
2007 Atsumi T, Cho YR, Leng L, McDonald C, Yu T, Danton C, Hong EG, Mitchell RA, Metz C, Niwa H, Takeuchi J, Onodera S, Umino T, Yoshioka N, Koike T, ... ... Bucala R, et al. The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 179: 5399-406. PMID 17911626 DOI: 10.4049/Jimmunol.179.8.5399  0.44
2007 Arjona A, Foellmer HG, Town T, Leng L, McDonald C, Wang T, Wong SJ, Montgomery RR, Fikrig E, Bucala R. Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. The Journal of Clinical Investigation. 117: 3059-66. PMID 17909632 DOI: 10.1172/Jci32218  0.4
2007 Lantner F, Starlets D, Gore Y, Flaishon L, Yamit-Hezi A, Dikstein R, Leng L, Bucala R, Machluf Y, Oren M, Shachar I. CD74 induces TAp63 expression leading to B-cell survival. Blood. 110: 4303-11. PMID 17846227 DOI: 10.1182/Blood-2007-04-087486  0.4
2007 Meyer-Siegler KL, Vera PL, Iczkowski KA, Bifulco C, Lee A, Gregersen PK, Leng L, Bucala R. Macrophage migration inhibitory factor (MIF) gene polymorphisms are associated with increased prostate cancer incidence. Genes and Immunity. 8: 646-52. PMID 17728788 DOI: 10.1038/Sj.Gene.6364427  0.44
2007 Binsky I, Haran M, Starlets D, Gore Y, Lantner F, Harpaz N, Leng L, Goldenberg DM, Shvidel L, Berrebi A, Bucala R, Shachar I. IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival. Proceedings of the National Academy of Sciences of the United States of America. 104: 13408-13. PMID 17686984 DOI: 10.1073/Pnas.0701553104  0.4
2007 Taylor JA, Kuchel GA, Hegde P, Voznesensky OS, Claffey K, Tsimikas J, Leng L, Bucala R, Pilbeam C. Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice. Bmc Cancer. 7: 135. PMID 17650334 DOI: 10.1186/1471-2407-7-135  0.44
2007 Cho Y, Jones BF, Vermeire JJ, Leng L, DiFedele L, Harrison LM, Xiong H, Kwong YK, Chen Y, Bucala R, Lolis E, Cappello M. Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74. The Journal of Biological Chemistry. 282: 23447-56. PMID 17567581 DOI: 10.1074/Jbc.M702950200  0.4
2007 Bernhagen J, Krohn R, Lue H, Gregory JL, Zernecke A, Koenen RR, Dewor M, Georgiev I, Schober A, Leng L, Kooistra T, Fingerle-Rowson G, Ghezzi P, Kleemann R, McColl SR, ... Bucala R, et al. MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nature Medicine. 13: 587-96. PMID 17435771 DOI: 10.1038/Nm1567  0.4
2007 Houdeau E, Moriez R, Leveque M, Salvador–Cartier C, Waget A, Leng L, Bueno L, Bucala R, Fioramonti J. Sex Steroid Regulation of Macrophage Migration Inhibitory Factor in Normal and Inflamed Colon in the Female Rat Gastroenterology. 132: 982-993. PMID 17324399 DOI: 10.1053/J.Gastro.2006.12.028  0.44
2007 Yu X, Lin SG, Huang XR, Bacher M, Leng L, Bucala R, Lan HY. Macrophage migration inhibitory factor induces MMP-9 expression in macrophages via the MEK-ERK MAP kinase pathway. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 27: 103-9. PMID 17316137 DOI: 10.1089/Jir.2006.0054  0.44
2007 Lue H, Thiele M, Franz J, Dahl E, Speckgens S, Leng L, Fingerle-Rowson G, Bucala R, Lüscher B, Bernhagen J. Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity. Oncogene. 26: 5046-59. PMID 17310986 DOI: 10.1038/Sj.Onc.1210318  0.44
2006 Wu SP, Leng L, Feng Z, Liu N, Zhao H, McDonald C, Lee A, Arnett FC, Gregersen PK, Mayes MD, Bucala R. Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis and Rheumatism. 54: 3661-9. PMID 17075815 DOI: 10.1002/Art.22179  0.44
2006 Wang B, Huang X, Wolters PJ, Sun J, Kitamoto S, Yang M, Riese R, Leng L, Chapman HA, Finn PW, David JR, Bucala R, Shi GP. Cutting edge: Deficiency of macrophage migration inhibitory factor impairs murine airway allergic responses. Journal of Immunology (Baltimore, Md. : 1950). 177: 5779-84. PMID 17056501 DOI: 10.4049/Jimmunol.177.9.5779  0.4
2006 Shi X, Leng L, Wang T, Wang W, Du X, Li J, McDonald C, Chen Z, Murphy JW, Lolis E, Noble P, Knudson W, Bucala R. CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity. 25: 595-606. PMID 17045821 DOI: 10.1016/J.Immuni.2006.08.020  0.4
2006 Tan KCB, Shiu SWM, Chow WS, Leng L, Bucala R, Betteridge DJ. Association between serum levels of soluble receptor for advanced glycation end products and circulating advanced glycation end products in type 2 diabetes Diabetologia. 49: 2756-2762. PMID 16969649 DOI: 10.1007/S00125-006-0394-1  0.44
2006 Telang S, Yalcin A, Clem AL, Bucala R, Lane AN, Eaton JW, Chesney J. Ras transformation requires metabolic control by 6-phosphofructo-2-kinase. Oncogene. 25: 7225-34. PMID 16715124 DOI: 10.1038/Sj.Onc.1209709  0.4
2006 McDevitt MA, Xie J, Ganapathy-Kanniappan S, Shanmugasundaram G, Griffith J, Liu A, McDonald C, Thuma P, Gordeuk VR, Metz CN, Mitchell R, Keefer J, David J, Leng L, Bucala R. A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. The Journal of Experimental Medicine. 203: 1185-96. PMID 16636133 DOI: 10.1084/Jem.20052398  0.44
2006 Leng L, Bucala R. Insight into the biology of macrophage migration inhibitory factor (MIF) revealed by the cloning of its cell surface receptor. Cell Research. 16: 162-168. PMID 16474429 DOI: 10.1038/Sj.Cr.7310022  0.44
2006 Jenison RD, Bucala R, Maul D, Ward DC. Thin-film technology for direct visual detection of nucleic acid sequences: applications in clinical research. Expert Review of Molecular Diagnostics. 6: 89-99. PMID 16359270 DOI: 10.1586/14737159.6.1.89  0.4
2006 Matsuura T, Sun C, Leng L, Kapurniotu A, Bernhagen J, Bucala R, Martynyuk AE, Sumners C. Macrophage migration inhibitory factor increases neuronal delayed rectifier K+ current. Journal of Neurophysiology. 95: 1042-8. PMID 16267117 DOI: 10.1152/Jn.00499.2005  0.44
2006 Lue H, Kapurniotu A, Fingerle-Rowson G, Roger T, Leng L, Thiele M, Calandra T, Bucala R, Bernhagen J. Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity. Cellular Signalling. 18: 688-703. PMID 16122907 DOI: 10.1016/J.Cellsig.2005.06.013  0.44
2006 Burger-Kentischer A, Göbel H, Kleemann R, Zernecke A, Bucala R, Leng L, Finkelmeier D, Geiger G, Schaefer HE, Schober A, Weber C, Brunner H, Rütten H, Ihling C, Bernhagen J. Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF). Atherosclerosis. 184: 28-38. PMID 15921687 DOI: 10.1016/J.Atherosclerosis.2005.03.028  0.4
2005 Bucala R, Lolis E. Macrophage migration inhibitory factor: a critical component of autoimmune inflammatory diseases. Drug News & Perspectives. 18: 417-26. PMID 16362080 DOI: 10.1358/Dnp.2005.18.7.939345  0.4
2005 Leng L, Bucala R. Macrophage migration inhibitory factor. Critical Care Medicine. 33. PMID 16340426 DOI: 10.1097/01.Ccm.0000191278.04636.D8  0.44
2005 Lashuel HA, Aljabari B, Sigurdsson EM, Metz CN, Leng L, Callaway DJ, Bucala R. Amyloid fibril formation by macrophage migration inhibitory factor. Biochemical and Biophysical Research Communications. 338: 973-80. PMID 16286092 DOI: 10.1016/J.Bbrc.2005.10.040  0.4
2005 Wilson JM, Coletta PL, Cuthbert RJ, Scott N, MacLennan K, Hawcroft G, Leng L, Lubetsky JB, Jin KK, Lolis E, Medina F, Brieva JA, Poulsom R, Markham AF, Bucala R, et al. Macrophage migration inhibitory factor promotes intestinal tumorigenesis. Gastroenterology. 129: 1485-503. PMID 16285950 DOI: 10.1053/J.Gastro.2005.07.061  0.4
2005 Jiang D, Liang J, Fan J, Yu S, Chen S, Luo Y, Prestwich GD, Mascarenhas MM, Garg HG, Quinn DA, Homer RJ, Goldstein DR, Bucala R, Lee PJ, Medzhitov R, et al. Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nature Medicine. 11: 1173-9. PMID 16244651 DOI: 10.1038/Nm1315  0.4
2005 Mizue Y, Ghani S, Leng L, McDonald C, Kong P, Baugh J, Lane SJ, Craft J, Nishihira J, Donnelly SC, Zhu Z, Bucala R. Role for macrophage migration inhibitory factor in asthma Proceedings of the National Academy of Sciences of the United States of America. 102: 14410-14415. PMID 16186482 DOI: 10.1073/Pnas.0507189102  0.44
2005 Zhong XB, Leng L, Beitin A, Chen R, McDonald C, Hsiao B, Jenison RD, Kang I, Park SH, Lee A, Gregersen P, Thuma P, Bray-Ward P, Ward DC, Bucala R. Simultaneous detection of microsatellite repeats and SNPs in the macrophage migration inhibitory factor (MIF) gene by thin-film biosensor chips and application to rural field studies. Nucleic Acids Research. 33: e121. PMID 16077028 DOI: 10.1093/Nar/Gni123  0.4
2005 Chesney J, Telang S, Yalcin A, Clem A, Wallis N, Bucala R. Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality. Biochemical and Biophysical Research Communications. 331: 139-46. PMID 15845370 DOI: 10.1016/J.Bbrc.2005.02.193  0.4
2005 Kong YZ, Huang XR, Ouyang X, Tan JJ, Fingerle-Rowson G, Bacher M, Mu W, Scher LA, Leng L, Bucala R, Lan HY. Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques. Cardiovascular Research. 65: 272-82. PMID 15621056 DOI: 10.1016/J.Cardiores.2004.09.020  0.44
2005 Tierney T, Patel R, Stead CAS, Leng L, Bucala R, Buckingham JC. Macrophage migration inhibitory factor is released from pituitary folliculo-stellate-like cells by endotoxin and dexamethasone and attenuates the steroid-induced inhibition of interleukin 6 release. Endocrinology. 146: 35-43. PMID 15388650 DOI: 10.1210/En.2004-0946  0.44
2005 Bucala R, Makita Z, Cerami A, Vlassara H, Koschinsky T. Advanced Glycosylation of LDL: Role in Oxidative Modification and Diabetic Complications Maillard Reactions in Chemistry, Food, and Health. 286-291. DOI: 10.1533/9781845698393.4.286  0.44
2004 Chen Z, Sakuma M, Zago AC, Zhang X, Shi C, Leng L, Mizue Y, Bucala R, Simon D. Evidence for a role of macrophage migration inhibitory factor in vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 709-14. PMID 14751814 DOI: 10.1161/01.Atv.0000119356.35748.9E  0.4
2003 Rice EK, Nikolic-Paterson DJ, Hill PA, Metz CN, Bucala R, Atkins RC, Tesch GH. Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells. Nephrology (Carlton, Vic.). 8: 156-61. PMID 15012733 DOI: 10.1046/J.1440-1797.2003.00152.X  0.4
2003 Lolis E, Bucala R. Therapeutic approaches to innate immunity: severe sepsis and septic shock. Nature Reviews. Drug Discovery. 2: 635-45. PMID 12904813 DOI: 10.1038/Nrd1153  0.4
2003 Lolis E, Bucala R. Macrophage migration inhibitory factor. Expert Opinion On Therapeutic Targets. 7: 153-64. PMID 12667094 DOI: 10.1517/14728222.7.2.153  0.4
2003 Pyle ME, Korbonits M, Gueorguiev M, Jordan S, Kola B, Morris DG, Meinhardt A, Powell MP, Claret FX, Zhang Q, Metz C, Bucala R, Grossman AB. Macrophage migration inhibitory factor expression is increased in pituitary adenoma cell nuclei. The Journal of Endocrinology. 176: 103-10. PMID 12525254 DOI: 10.1677/Joe.0.1760103  0.4
2002 Dios A, Mitchell RA, Aljabari B, Lubetsky J, O'Connor K, Liao H, Senter PD, Manogue KR, Lolis E, Metz C, Bucala R, Callaway DJ, Al-Abed Y. Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity. Journal of Medicinal Chemistry. 45: 2410-6. PMID 12036350 DOI: 10.1021/Jm010534Q  0.4
2002 Senter PD, Al-Abed Y, Metz CN, Benigni F, Mitchell RA, Chesney J, Han J, Gartner CG, Nelson SD, Todaro GJ, Bucala R. Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites. Proceedings of the National Academy of Sciences of the United States of America. 99: 144-9. PMID 11773615 DOI: 10.1073/Pnas.011569399  0.4
2001 Al-Abed Y, VanPatten S, Li H, Lawson JA, FitzGerald GA, Manogue KR, Bucala R. Characterization of a novel hemoglobin-glutathione adduct that is elevated in diabetic patients. Molecular Medicine (Cambridge, Mass.). 7: 619-23. PMID 11778651 DOI: 10.1007/Bf03401868  0.4
2001 Hartlapp I, Riichiro ABE, Saeed RW, Peng T, Voelter W, Bucala R, Metz CN. Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo . 15: 2215-2224. PMID 11641248 DOI: 10.1096/Fj.01-0049Com  0.4
2000 Zhu Y, Koo K, Bradshaw JD, Sutton WF, Kuller LR, Bucala R, Anderson D, Mossman SP, Villinger F, Haigwood NL. Macaque blood-derived antigen-presenting cells elicit SIV-specific immune responses. Journal of Medical Primatology. 29: 182-92. PMID 11085581 DOI: 10.1034/J.1600-0684.2000.290312.X  0.4
1999 Al-Abed Y, Mitsuhashi T, Li H, Lawson JA, FitzGerald GA, Founds H, Donnelly T, Cerami A, Ulrich P, Bucala R. Inhibition of advanced glycation endproduct formation by acetaldehyde: role in the cardioprotective effect of ethanol. Proceedings of the National Academy of Sciences of the United States of America. 96: 2385-90. PMID 10051651 DOI: 10.1073/Pnas.96.5.2385  0.4
1998 al-Abed Y, Schleicher E, Voelter W, Liebich H, Papoulis A, Bucala R. Identification of N2-(1-carboxymethyl)guanine (CMG) as a guanine advanced glycation end product. Bioorganic & Medicinal Chemistry Letters. 8: 2109-10. PMID 9873495 DOI: 10.1016/S0960-894X(98)00398-9  0.4
1998 Pastrana DV, Raghavan N, Fitzgerald P, Eisinger SW, Metz C, Bucala R, Schleimer RP, Bickel C, Scott AL. Filarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor Infection and Immunity. 66: 5955-5963. PMID 9826378 DOI: 10.1128/Iai.66.12.5955-5963.1998  0.4
1998 Kapurniotu A, Bernhagen J, Greenfield N, Al-Abed Y, Teichberg S, Frank RW, Voelter W, Bucala R. Contribution of advanced glycosylation to the amyloidogenicity of islet and amyloid polypeptide European Journal of Biochemistry. 251: 208-216. PMID 9492286 DOI: 10.1046/J.1432-1327.1998.2510208.X  0.4
1998 Sherry B, Zybarth G, Alfano M, Dubrovsky L, Mitchell R, Rich D, Ulrich P, Bucala R, Cerami A, Bukrinsky M. Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 95: 1758-63. PMID 9465090 DOI: 10.1073/Pnas.95.4.1758  0.4
1997 Fishbane S, Bucala R, Pereira BJG, Founds H, Vlassara H. Reduction of plasma apolipoprotein-B by effective removal of circulating glycation derivatives in uremia Kidney International. 52: 1645-1650. PMID 9407512 DOI: 10.1038/Ki.1997.497  0.44
1997 Bendrat K, Al-Abed Y, Callaway DJ, Peng T, Calandra T, Metz CN, Bucala R. Biochemical and mutational investigations of the enzymatic activity of macrophage migration inhibitory factor. Biochemistry. 36: 15356-62. PMID 9398265 DOI: 10.1021/Bi971153A  0.4
1997 Cerami C, Founds H, Nicholl I, Mitsuhashi T, Giordano D, Vanpatten S, Lee A, Al-Abed Y, Vlassara H, Bucala R, Cerami A. Tobacco smoke is a source of toxic reactive glycation products. Proceedings of the National Academy of Sciences of the United States of America. 94: 13915-20. PMID 9391127 DOI: 10.1073/Pnas.94.25.13915  0.4
1997 Stitt AW, Bucala R, Vlassara H. Atherogenesis and advanced glycation: promotion, progression, and prevention. Annals of the New York Academy of Sciences. 811: 115-129. PMID 9186590 DOI: 10.1111/J.1749-6632.1997.Tb51994.X  0.44
1997 Koschinsky T, He C, Mitsuhashi T, Bucala R, Liu C, Buenting C, Heitmann K, Vlassara H. Orally absorbed reactive glycation products (glycotoxins): An environmental risk factor in diabetic nephropathy Proceedings of the National Academy of Sciences of the United States of America. 94: 6474-6479. PMID 9177242 DOI: 10.1073/Pnas.94.12.6474  0.44
1997 Donnelly SC, Haslett C, Reid PT, Grant IS, Wallace WAH, Metz CN, Bruce LJ, Bucala R. Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome Nature Medicine. 3: 320-323. PMID 9055860 DOI: 10.1038/Nm0397-320  0.4
1997 Stitt AW, He C, Friedman S, Scher LA, Rossi P, Ong L, Founds H, Li YM, Bucala R, Vlassara H. Elevated AGE-modified ApoB in sera of euglycemic, normolipidemic patients with atherosclerosis: Relationship to tissue AGEs Molecular Medicine. 3: 617-627. DOI: 10.1007/Bf03401819  0.44
1996 Makita Z, Yanagisawa K, Kuwajima S, Bucala R, Vlassara H, Koike T. The role of advanced glycosylation end-products in the pathogenesis of atherosclerosis Nephrology Dialysis Transplantation. 11: 31-33. PMID 9044304 DOI: 10.1093/Ndt/11.Supp5.31  0.44
1996 Rosengren E, Bucala R, Aman P, Jacobsson L, Odh G, Metz CN, Rorsman H. The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction. Molecular Medicine (Cambridge, Mass.). 2: 143-9. PMID 8900542 DOI: 10.1007/Bf03402210  0.4
1996 Sun HW, Swope M, Cinquina C, Bedarkar S, Bernhagen J, Bucala R, Lolis E. The subunit structure of human macrophage migration inhibitory factor: Evidence for a trimer Protein Engineering. 9: 631-635. PMID 8875640 DOI: 10.1093/Protein/9.8.631  0.4
1996 Vasan S, Zhang X, Zhang X, Kapurniotu A, Bernhagen J, Teichberg S, Basgen J, Wagle D, Shih D, Terlecky I, Bucala R, Cerami A, Egan J, Ulrich P. An agent cleaving glucose-derived protein crosslinks in vitro and in vivo. Nature. 382: 275-8. PMID 8717046 DOI: 10.1038/382275A0  0.4
1996 Vlassara H, Bucala R. Recent progress in advanced glycation and diabetic vascular disease: role of advanced glycation end product receptors. Diabetes. 45. PMID 8674896 DOI: 10.2337/Diab.45.3.S65  0.44
1996 Sun HW, Bernhagen J, Bucala R, Lolis E. Crystal structure at 2.6-Å resolution of human macrophage migration inhibitory factor Proceedings of the National Academy of Sciences of the United States of America. 93: 5191-5196. PMID 8643551 DOI: 10.1073/Pnas.93.11.5191  0.4
1996 Li YM, Steffes MW, Donnelly T, Liu C, Fuh H, Basgen J, Bucala R, Vlassara H. Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine. Proceedings of the National Academy of Sciences of the United States of America. 93: 3902-3907. PMID 8632987 DOI: 10.1073/Pnas.93.9.3902  0.44
1995 Lee AT, Plump A, DeSimone C, Cerami A, Bucala R. A role for DNA mutations in diabetes-associated teratogenesis in transgenic embryos Diabetes. 44: 20-24. PMID 7813809 DOI: 10.2337/Diab.44.1.20  0.4
1995 Beisswenger PJ, Makita Z, Curphey TJ, Moore LL, Jean S, Brinck-Johnsen T, Bucala R, Vlassara H. Formation of immunochemical advanced glycosylation end products precedes and correlates with early manifestations of renal and retinal disease in diabetes. Diabetes. 44: 824-829. PMID 7789650 DOI: 10.2337/Diab.44.7.824  0.44
1995 Bucala R, Mitchell R, Arnold K, Innerarity T, Vlassara H, Cerami A. Identification of the major site of apolipoprotein B modification by advanced glycosylation end products blocking uptake by the low density lipoprotein receptor Journal of Biological Chemistry. 270: 10828-10832. PMID 7738020 DOI: 10.1074/Jbc.270.18.10828  0.4
1995 Calandra T, Bernhagen J, Metz CN, Spiegel LA, Bacher M, Donnelly T, Cerami A, Bucala R. MIF as a glucocorticoid-induced modulator of cytokine production. Nature. 377: 68-71. PMID 7659164 DOI: 10.1038/377068A0  0.4
1995 Bucala R, Vlassara H. Advanced glycosylation endproducts in diabetic renal disease : clinical measurement, pathophysiological significance, and prospects for pharmacological inhibition Blood Purification. 13: 160-170. PMID 7619388 DOI: 10.1159/000170199  0.44
1995 Bucala R, Vlassara H. Advanced glycosylation end products in diabetic renal and vascular disease American Journal of Kidney Diseases. 26: 875-888. PMID 7503061 DOI: 10.1016/0272-6386(95)90051-9  0.44
1995 Al-Abed Y, Ulrich P, Kapurniotu A, Lolis E, Bucala R. Model studies of the maillard reaction of Arg-Lys with D-ribose Bioorganic and Medicinal Chemistry Letters. 5: 2929-2930. DOI: 10.1016/0960-894X(95)00513-S  0.4
1994 Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair Molecular Medicine (Cambridge, Mass.). 1: 71-81. PMID 8790603 DOI: 10.1007/Bf03403533  0.4
1994 Vitek MP, Bhattacharya K, Glendening JM, Stopa E, Vlassara H, Bucala R, Manogue K, Cerami A. Advanced glycation end products contribute to amyloidosis in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 4766-70. PMID 8197133 DOI: 10.1073/Pnas.91.11.4766  0.4
1994 Lee AT, Desimone C, Cerami A, Bucala R. Comparative analysis of DNA mutations in lacI transgenic mice with age Faseb Journal. 8: 545-550. PMID 8181674 DOI: 10.1096/Fasebj.8.8.8181674  0.4
1994 Bernhagen J, Calandra T, Cerami A, Bucala R. Macrophage migration inhibitory factor is a neuroendocrine mediator of endotoxaemia Trends in Microbiology. 2: 198-201. PMID 8087451 DOI: 10.1016/0966-842X(94)90111-H  0.4
1994 Hogan M, Sherry B, Ritchlin C, Fabre M, Winchester R, Cerami A, Bucala R. Differential expression of the small inducible cytokines GRO α and GROβ by synovial fibroblasts in chronic arthritis: Possible role in growth regulation Cytokine. 6: 61-69. PMID 8003635 DOI: 10.1016/1043-4666(94)90009-4  0.4
1994 Bernhagen J, Mitchell RA, Calandra T, Voelter W, Cerami A, Bucala R. Purification, bioactivity, and secondary structure analysis of mouse and human macrophage Migration Inhibitory Factor (MIF) Biochemistry. 33: 14144-14155. PMID 7947826 DOI: 10.1021/Bi00251A025  0.4
1994 Bucala R, Makita Z, Vega G, Grundy S, Koschinsky T, Cerami A, Vlassara H. Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency Proceedings of the National Academy of Sciences of the United States of America. 91: 9441-9445. PMID 7937786 DOI: 10.1073/Pnas.91.20.9441  0.4
1994 Bucala R, Vlassara H, Cerami A. Advanced glycosylation endproducts: Role in diabetic and non-diabetic vascular disease Drug Development Research. 32: 77-89. DOI: 10.1002/Ddr.430320204  0.4
1993 Bernhagen J, Calandra T, Mitchell RA, Martin SB, Tracey KJ, Voelter W, Manogue KR, Cerami A, Bucala R. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature. 365: 756-9. PMID 8413654 DOI: 10.1038/365756A0  0.4
1993 Bucala R, Lee AT, Rourke L, Cerami A. Transposition of an Alu-containing element induced by DNA-advanced glycosylation endproducts Proceedings of the National Academy of Sciences of the United States of America. 90: 2666-2670. PMID 8385341 DOI: 10.1073/Pnas.90.7.2666  0.4
1993 Bucala R, Makita Z, Koschinsky T, Cerami A, Vlassara H. Lipid advanced glycosylation: Pathway for lipid oxidation in vivo Proceedings of the National Academy of Sciences of the United States of America. 90: 6434-6438. PMID 8341651 DOI: 10.1073/Pnas.90.14.6434  0.4
1992 Hogan M, Cerami A, Bucala R. Advanced glycosylation endproducts block the antiproliferative effect of nitric oxide: Role in the vascular and renal complications of diabetes mellitus Journal of Clinical Investigation. 90: 1110-1115. PMID 1522220 DOI: 10.1172/Jci115928  0.4
1992 Vlassara H, Fuh H, Makita Z, Krungkrai S, Cerami A, Bucala R. Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: A model for diabetic and aging complications Proceedings of the National Academy of Sciences of the United States of America. 89: 12043-12047. PMID 1465438 DOI: 10.1073/Pnas.89.24.12043  0.4
1992 Makita Z, Vlassara H, Rayfield E, Cartwright K, Friedman E, Rodby R, Cerami A, Bucala R. Hemoglobin-AGE: A circulating marker of advanced glycosylation Science. 258: 651-653. PMID 1411574 DOI: 10.1126/Science.1411574  0.4
1985 Bucala R, Model P, Russel M, Cerami A. Modification of DNA by glucose 6-phosphate induces DNA rearrangements in an Escherichia coli plasmid Proceedings of the National Academy of Sciences of the United States of America. 82: 8439-8442. PMID 3866232 DOI: 10.1073/Pnas.82.24.8439  0.4
1984 Bucala R, Model P, Cerami A. Modification of DNA by reducing sugars: A possible mechanism for nucleic acid aging and age-related dysfunction in gene expression Proceedings of the National Academy of Sciences of the United States of America. 81: 105-109. PMID 6582469 DOI: 10.1073/Pnas.81.1.105  0.4
1984 Manabe S, Bucala R, Cerami A. Nonenzymatic addition of glucocorticoids to lens proteins in steroid-induced cataracts Journal of Clinical Investigation. 74: 1803-1810. PMID 6501572 DOI: 10.1172/Jci111599  0.4
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