Fatah Kashanchi - Publications

Biomedical Sciences The George Washington University, Washington, DC, United States 
Microbiology Biology, Molecular Biology, Virology Biology

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pinto DO, Scott TA, DeMarino C, Pleet ML, Vo TT, Saifuddin M, Kovalskyy D, Erickson J, Cowen M, Barclay RA, Zeng C, Weinberg MS, Kashanchi F. Effect of transcription inhibition and generation of suppressive viral non-coding RNAs. Retrovirology. 16: 13. PMID 31036006 DOI: 10.1186/s12977-019-0475-0  0.56
2018 Pleet ML, Mathiesen A, DeMarino C, Akpamagbo YA, Barclay RA, Schwab A, Iordanskiy S, Sampey GC, Lepene B, Ilinykh PA, Bukreyev A, Nekhai S, Aman MJ, Kashanchi F. Corrigendum: Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. Frontiers in Microbiology. 9: 692. PMID 29696006 DOI: 10.3389/fmicb.2018.00692  0.52
2017 Lin X, Kumari N, DeMarino C, Kont YS, Ammosova T, Kulkarni A, Jerebtsova M, Vazquez-Meves G, Ivanov A, Dmytro K, Üren A, Kashanchi F, Nekhai S. Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03. Oncotarget. 8: 76749-76769. PMID 29100346 DOI: 10.18632/oncotarget.19999  0.52
2017 Barclay RA, Schwab A, DeMarino C, Akpamagbo Y, Lepene B, Kassaye S, Iordanskiy S, Kashanchi F. Exosomes from uninfected cells activate transcription of latent HIV-1. The Journal of Biological Chemistry. 292: 14764. PMID 28887434 DOI: 10.1074/jbc.A117.793521  0.48
2017 Akpamagbo YA, DeMarino C, Pleet ML, Schwab A, Rodriguez M, Barclay RA, Sampey G, Iordanskiy S, El-Hage N, Kashanchi F. HIV-1 Transcription Inhibitors Increase the Synthesis of Viral Non-Coding RNA that Contribute to Latency. Current Pharmaceutical Design. PMID 28641535 DOI: 10.2174/1381612823666170622101319  0.64
2017 Barclay RA, Schwab A, DeMarino C, Akpamagbo Y, Lepene B, Kassaye S, Iordanskiy S, Kashanchi F. Exosomes from uninfected cells activate transcription of latent HIV-1. The Journal of Biological Chemistry. PMID 28536264 DOI: 10.1074/jbc.M117.793521  0.48
2016 Pleet ML, Mathiesen A, DeMarino C, Akpamagbo YA, Barclay RA, Schwab A, Iordanskiy S, Sampey GC, Lepene B, Nekhai S, Aman MJ, Kashanchi F. Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. Frontiers in Microbiology. 7: 1765. PMID 27872619 DOI: 10.3389/fmicb.2016.01765  0.52
2016 DeMarino C, Schwab A, Pleet M, Mathiesen A, Friedman J, El-Hage N, Kashanchi F. Biodegradable Nanoparticles for Delivery of Therapeutics in CNS Infection. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 27372507 DOI: 10.1007/s11481-016-9692-7  0.68
2016 Aman MJ, Kashanchi F. Zika Virus: A New Animal Model for an Arbovirus. Plos Neglected Tropical Diseases. 10: e0004702. PMID 27149628 DOI: 10.1371/journal.pntd.0004702  0.68
2016 Ahsan NA, Sampey GC, Lepene B, Akpamagbo Y, Barclay RA, Iordanskiy S, Hakami RM, Kashanchi F. Presence of Viral RNA and Proteins in Exosomes from Cellular Clones Resistant to Rift Valley Fever Virus Infection. Frontiers in Microbiology. 7: 139. PMID 26904012 DOI: 10.3389/fmicb.2016.00139  0.52
2016 Iordanskiy S, Kashanchi F. Potential of Radiation-Induced Cellular Stress for Reactivation of Latent HIV-1 and Killing of Infected Cells. Aids Research and Human Retroviruses. 32: 120-4. PMID 26765533 DOI: 10.1089/AID.2016.0006  0.48
2015 Sardo L, Iordanskiy S, Klase Z, Kashanchi F. HIV-1 Nef blocks autophagy in human astrocytes. Cell Cycle (Georgetown, Tex.). 14: 3781-2. PMID 26697833 DOI: 10.1080/15384101.2015.1105700  0.6
2015 Sampey GC, Saifuddin M, Schwab A, Barclay R, Punya S, Chung MC, Hakami RM, Asad Zadeh M, Lepene B, Klase ZA, El-Hage N, Young M, Iordanskiy S, Kashanchi F. Exosomes from HIV-1 infected cells stimulate production of pro-inflammatory cytokines through TAR RNA. The Journal of Biological Chemistry. PMID 26553869 DOI: 10.1074/jbc.M115.662171  0.68
2015 Schwab A, Meyering SS, Lepene B, Iordanskiy S, van Hoek ML, Hakami RM, Kashanchi F. Extracellular vesicles from infected cells: potential for direct pathogenesis. Frontiers in Microbiology. 6: 1132. PMID 26539170 DOI: 10.3389/fmicb.2015.01132  0.48
2015 Iordanskiy S, Van Duyne R, Sampey GC, Woodson CM, Fry K, Saifuddin M, Guo J, Wu Y, Romerio F, Kashanchi F. Therapeutic doses of irradiation activate viral transcription and induce apoptosis in HIV-1 infected cells. Virology. 485: 1-15. PMID 26184775 DOI: 10.1016/j.virol.2015.06.021  0.68
2015 Tyagi M, Iordanskiy S, Ammosova T, Kumari N, Smith K, Breuer D, Ilatovskiy AV, Kont YS, Ivanov A, Üren A, Kovalskyy D, Petukhov M, Kashanchi F, Nekhai S. Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1. Retrovirology. 12: 63. PMID 26178009 DOI: 10.1186/s12977-015-0190-4  0.52
2015 Guendel I, Iordanskiy S, Sampey GC, Van Duyne R, Calvert V, Petricoin E, Saifuddin M, Kehn-Hall K, Kashanchi F. Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells. Journal of Neurovirology. 21: 257-75. PMID 25672887 DOI: 10.1007/s13365-015-0323-5  0.68
2015 Turpin J, Journo C, Ko NL, Sinet F, Carpentier A, Galioot A, Edwards D, Vandamme AM, Gazzolo L, Duc Dodon M, Gessain A, Kashanchi F, Balansard I, Lacoste R, Mahieux R. Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses. Journal of Virology. 89: 931-51. PMID 25355890 DOI: 10.1128/JVI.02150-14  0.68
2014 Chen H, Zhao Y, Li H, Zhang D, Huang Y, Shen Q, Van Duyne R, Kashanchi F, Zeng C, Liu S. Break CDK2/Cyclin E1 interface allosterically with small peptides. Plos One. 9: e109154. PMID 25290691 DOI: 10.1371/journal.pone.0109154  0.68
2014 Kumari N, Iordanskiy S, Kovalskyy D, Breuer D, Niu X, Lin X, Xu M, Gavrilenko K, Kashanchi F, Dhawan S, Nekhai S. Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription. Antimicrobial Agents and Chemotherapy. 58: 6558-71. PMID 25155598 DOI: 10.1128/AAC.02918-14  0.52
2014 Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, ... ... Kashanchi F, et al. Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. The Journal of Biological Chemistry. 289: 22284-305. PMID 24939845 DOI: 10.1074/jbc.M114.549659  0.68
2014 Jaworski E, Saifuddin M, Sampey G, Shafagati N, Van Duyne R, Iordanskiy S, Kehn-Hall K, Liotta L, Petricoin E, Young M, Lepene B, Kashanchi F. The use of Nanotrap particles technology in capturing HIV-1 virions and viral proteins from infected cells. Plos One. 9: e96778. PMID 24820173 DOI: 10.1371/journal.pone.0096778  0.68
2014 Amaya M, Voss K, Sampey G, Senina S, de la Fuente C, Mueller C, Calvert V, Kehn-Hall K, Carpenter C, Kashanchi F, Bailey C, Mogelsvang S, Petricoin E, Narayanan A. The role of IKKβ in Venezuelan equine encephalitis virus infection. Plos One. 9: e86745. PMID 24586253 DOI: 10.1371/journal.pone.0086745  0.68
2014 Sampey GC, Meyering SS, Asad Zadeh M, Saifuddin M, Hakami RM, Kashanchi F. Exosomes and their role in CNS viral infections. Journal of Neurovirology. 20: 199-208. PMID 24578033 DOI: 10.1007/s13365-014-0238-6  0.56
2014 Napier TC, Chen L, Kashanchi F, Hu XT. Repeated cocaine treatment enhances HIV-1 Tat-induced cortical excitability via over-activation of L-type calcium channels. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 354-68. PMID 24567038 DOI: 10.1007/s11481-014-9524-6  0.68
2014 Fleming A, Sampey G, Chung MC, Bailey C, van Hoek ML, Kashanchi F, Hakami RM. The carrying pigeons of the cell: exosomes and their role in infectious diseases caused by human pathogens. Pathogens and Disease. 71: 109-20. PMID 24449527 DOI: 10.1111/2049-632X.12135  0.64
2014 Narayanan A, Amaya M, Voss K, Chung M, Benedict A, Sampey G, Kehn-Hall K, Luchini A, Liotta L, Bailey C, Kumar A, Bavari S, Hakami RM, Kashanchi F. Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells. Virology. 449: 270-86. PMID 24418562 DOI: 10.1016/j.virol.2013.11.023  0.68
2014 Guendel I, Iordanskiy S, Van Duyne R, Kehn-Hall K, Saifuddin M, Das R, Jaworski E, Sampey GC, Senina S, Shultz L, Narayanan A, Chen H, Lepene B, Zeng C, Kashanchi F. Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication. Journal of Virology. 88: 1189-208. PMID 24227837 DOI: 10.1128/JVI.01940-13  0.68
2013 Shafagati N, Narayanan A, Baer A, Fite K, Pinkham C, Bailey C, Kashanchi F, Lepene B, Kehn-Hall K. The use of NanoTrap particles as a sample enrichment method to enhance the detection of Rift Valley Fever Virus. Plos Neglected Tropical Diseases. 7: e2296. PMID 23861988 DOI: 10.1371/journal.pntd.0002296  0.68
2013 Narayanan A, Iordanskiy S, Das R, Van Duyne R, Santos S, Jaworski E, Guendel I, Sampey G, Dalby E, Iglesias-Ussel M, Popratiloff A, Hakami R, Kehn-Hall K, Young M, Subra C, ... ... Kashanchi F, et al. Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA. The Journal of Biological Chemistry. 288: 20014-33. PMID 23661700 DOI: 10.1074/jbc.M112.438895  0.68
2013 Klase ZA, Sampey GC, Kashanchi F. Retrovirus infected cells contain viral microRNAs. Retrovirology. 10: 15. PMID 23391025 DOI: 10.1186/1742-4690-10-15  0.68
2013 Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, Zeng C, Kovalskyy D, El Kouni MH, Lepene B, Patanarut A, Nekhai S, Price DH, Kashanchi F. Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription. Journal of Molecular Biology. 425: 812-29. PMID 23247501 DOI: 10.1016/j.jmb.2012.12.005  0.68
2013 Chung MC, Narayanan A, Popova TG, Kashanchi F, Bailey CL, Popov SG. Bacillus anthracis-derived nitric oxide induces protein S-nitrosylation contributing to macrophage death. Biochemical and Biophysical Research Communications. 430: 125-30. PMID 23178574 DOI: 10.1016/j.bbrc.2012.11.042  0.68
2013 Tonry JH, Popov SG, Narayanan A, Kashanchi F, Hakami RM, Carpenter C, Bailey C, Chung MC. In vivo murine and in vitro M-like cell models of gastrointestinal anthrax. Microbes and Infection / Institut Pasteur. 15: 37-44. PMID 23108317 DOI: 10.1016/j.micinf.2012.10.004  0.68
2012 Sampey GC, Guendel I, Das R, Jaworski E, Klase Z, Narayanan A, Kehn-Hall K, Kashanchi F. Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 Infections. Biology. 1: 339-69. PMID 24832229 DOI: 10.3390/biology1020339  0.68
2012 Sampey GC, Van Duyne R, Currer R, Das R, Narayanan A, Kashanchi F. Complex role of microRNAs in HTLV-1 infections. Frontiers in Genetics. 3: 295. PMID 23251140 DOI: 10.3389/fgene.2012.00295  0.68
2012 Currer R, Van Duyne R, Jaworski E, Guendel I, Sampey G, Das R, Narayanan A, Kashanchi F. HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways. Frontiers in Microbiology. 3: 406. PMID 23226145 DOI: 10.3389/fmicb.2012.00406  0.68
2012 Breuer D, Kotelkin A, Ammosova T, Kumari N, Ivanov A, Ilatovskiy AV, Beullens M, Roane PR, Bollen M, Petukhov MG, Kashanchi F, Nekhai S. CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology. 9: 94. PMID 23140174 DOI: 10.1186/1742-4690-9-94  0.52
2012 Narayanan A, Kehn-Hall K, Senina S, Lundberg L, Van Duyne R, Guendel I, Das R, Baer A, Bethel L, Turell M, Hartman AL, Das B, Bailey C, Kashanchi F. Curcumin inhibits Rift Valley fever virus replication in human cells. The Journal of Biological Chemistry. 287: 33198-214. PMID 22847000 DOI: 10.1074/jbc.M112.356535  0.68
2012 Wayman WN, Dodiya HB, Persons AL, Kashanchi F, Kordower JH, Hu XT, Napier TC. Enduring cortical alterations after a single in-vivo treatment of HIV-1 Tat. Neuroreport. 23: 825-9. PMID 22828409 DOI: 10.1097/WNR.0b013e3283578050  0.68
2012 Van Duyne R, Guendel I, Klase Z, Narayanan A, Coley W, Jaworski E, Roman J, Popratiloff A, Mahieux R, Kehn-Hall K, Kashanchi F. Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery. Plos One. 7: e40662. PMID 22808228 DOI: 10.1371/journal.pone.0040662  0.68
2012 Narayanan A, Sampey G, Van Duyne R, Guendel I, Kehn-Hall K, Roman J, Currer R, Galons H, Oumata N, Joseph B, Meijer L, Caputi M, Nekhai S, Kashanchi F. Use of ATP analogs to inhibit HIV-1 transcription. Virology. 432: 219-31. PMID 22771113 DOI: 10.1016/j.virol.2012.06.007  0.68
2012 Henderson LJ, Narasipura SD, Adarichev V, Kashanchi F, Al-Harthi L. Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, β-catenin, and SMAR1 to repress HIV transcription. Journal of Virology. 86: 9495-503. PMID 22674979 DOI: 10.1128/JVI.00486-12  0.68
2012 Austin D, Baer A, Lundberg L, Shafagati N, Schoonmaker A, Narayanan A, Popova T, Panthier JJ, Kashanchi F, Bailey C, Kehn-Hall K. p53 Activation following Rift Valley fever virus infection contributes to cell death and viral production. Plos One. 7: e36327. PMID 22574148 DOI: 10.1371/journal.pone.0036327  0.68
2012 Kehn-Hall K, Narayanan A, Lundberg L, Sampey G, Pinkham C, Guendel I, Van Duyne R, Senina S, Schultz KL, Stavale E, Aman MJ, Bailey C, Kashanchi F. Modulation of GSK-3β activity in Venezuelan equine encephalitis virus infection. Plos One. 7: e34761. PMID 22496857 DOI: 10.1371/journal.pone.0034761  0.68
2012 Tonry JH, McNichol BA, Ramarao N, Chertow DS, Kim KS, Stibitz S, Schneewind O, Kashanchi F, Bailey CL, Popov S, Chung MC. Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells. Cellular Microbiology. 14: 1219-30. PMID 22452315 DOI: 10.1111/j.1462-5822.2012.01791.x  0.68
2012 Dubrovsky L, Van Duyne R, Senina S, Guendel I, Pushkarsky T, Sviridov D, Kashanchi F, Bukrinsky M. Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection. Biochemical and Biophysical Research Communications. 419: 95-8. PMID 22326260 DOI: 10.1016/j.bbrc.2012.01.137  0.68
2012 Baer A, Austin D, Narayanan A, Popova T, Kainulainen M, Bailey C, Kashanchi F, Weber F, Kehn-Hall K. Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication. The Journal of Biological Chemistry. 287: 7399-410. PMID 22223653 DOI: 10.1074/jbc.M111.296608  0.68
2012 Shrestha B, Sripadi P, Walsh CM, Razunguzwa TT, Powell MJ, Kehn-Hall K, Kashanchi F, Vertes A. Rapid, non-targeted discovery of biochemical transformation and biomarker candidates in oncovirus-infected cell lines using LAESI mass spectrometry. Chemical Communications (Cambridge, England). 48: 3700-2. PMID 22167302 DOI: 10.1039/c2cc17225a  0.68
2012 Narasipura SD, Henderson LJ, Fu SW, Chen L, Kashanchi F, Al-Harthi L. Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes. Journal of Virology. 86: 1911-21. PMID 22156527 DOI: 10.1128/JVI.06266-11  0.68
2011 Duyne RV, Narayanan A, K-Hall K, Saifuddin M, Shultz L, Kashanchi F. Humanized mouse models of HIV-1 latency. Current Hiv Research. 9: 595-605. PMID 22211664 DOI: 10.2174/157016211798998781  0.68
2011 Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Varying modulation of HIV-1 LTR activity by Baf complexes. Journal of Molecular Biology. 411: 581-96. PMID 21699904 DOI: 10.1016/j.jmb.2011.06.001  0.68
2011 Narayanan A, Popova T, Turell M, Kidd J, Chertow J, Popov SG, Bailey C, Kashanchi F, Kehn-Hall K. Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection. Plos One. 6: e20354. PMID 21655261 DOI: 10.1371/journal.pone.0020354  0.68
2011 Kehn-Hall K, Guendel I, Carpio L, Skaltsounis L, Meijer L, Al-Harthi L, Steiner JP, Nath A, Kutsch O, Kashanchi F. Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology. 415: 56-68. PMID 21514616 DOI: 10.1016/j.virol.2011.03.025  0.68
2011 Chung MC, Tonry JH, Narayanan A, Manes NP, Mackie RS, Gutting B, Mukherjee DV, Popova TG, Kashanchi F, Bailey CL, Popov SG. Bacillus anthracis interacts with plasmin(ogen) to evade C3b-dependent innate immunity. Plos One. 6: e18119. PMID 21464960 DOI: 10.1371/journal.pone.0018119  0.68
2011 Chung MC, Jorgensen SC, Tonry JH, Kashanchi F, Bailey C, Popov S. Secreted Bacillus anthracis proteases target the host fibrinolytic system. Fems Immunology and Medical Microbiology. 62: 173-81. PMID 21395696 DOI: 10.1111/j.1574-695X.2011.00798.x  0.68
2011 Narayanan A, Bailey C, Kashanchi F, Kehn-Hall K. Developments in antivirals against influenza, smallpox and hemorrhagic fever viruses. Expert Opinion On Investigational Drugs. 20: 239-54. PMID 21235430 DOI: 10.1517/13543784.2011.547852  0.68
2011 Atkins JL, Gorbunov NV, Trabosh V, Van Duyne R, Kashanchi F, Komarov AM. Ferrous iron is found in mesenteric lymph bound to TIMP-2 following hemorrhage/resuscitation. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 24: 279-89. PMID 21229381 DOI: 10.1007/s10534-010-9394-1  0.68
2011 Narayanan A, Kehn-Hall K, Bailey C, Kashanchi F. Analysis of the roles of HIV-derived microRNAs. Expert Opinion On Biological Therapy. 11: 17-29. PMID 21133815 DOI: 10.1517/14712598.2011.540564  0.68
2011 Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9. Molecular Pharmacology. 79: 185-96. PMID 20956357 DOI: 10.1124/mol.110.069062  0.68
2010 Xu M, Kashanchi F, Foster A, Rotimi J, Turner W, Gordeuk VR, Nekhai S. Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology. 7: 104. PMID 21126372 DOI: 10.1186/1742-4690-7-104  0.52
2010 Popova TG, Turell MJ, Espina V, Kehn-Hall K, Kidd J, Narayanan A, Liotta L, Petricoin EF, Kashanchi F, Bailey C, Popov SG. Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells. Plos One. 5: e13805. PMID 21072193 DOI: 10.1371/journal.pone.0013805  0.68
2010 Carpio L, Klase Z, Coley W, Guendel I, Choi S, Van Duyne R, Narayanan A, Kehn-Hall K, Meijer L, Kashanchi F. Erratum to: microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection. Journal of Rnai and Gene Silencing : An International Journal of Rna and Gene Targeting Research. 6: E386. PMID 20963190  0.68
2010 Sripadi P, Shrestha B, Easley RL, Carpio L, Kehn-Hall K, Chevalier S, Mahieux R, Kashanchi F, Vertes A. Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry. Plos One. 5. PMID 20830293 DOI: 10.1371/journal.pone.0012590  0.68
2010 Carpio L, Klase Z, Coley W, Guendel I, Choi S, Van Duyne R, Narayanan A, Kehn-Hall K, Meijer L, Kashanchi F. microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection. Journal of Rnai and Gene Silencing : An International Journal of Rna and Gene Targeting Research. 6: 386-400. PMID 20628499  0.68
2010 Guendel I, Carpio L, Pedati C, Schwartz A, Teal C, Kashanchi F, Kehn-Hall K. Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function. Plos One. 5: e11379. PMID 20614009 DOI: 10.1371/journal.pone.0011379  0.68
2010 Van Duyne R, Guendel I, Kehn-Hall K, Easley R, Klase Z, Liu C, Young M, Kashanchi F. The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients. Aids Research and Therapy. 7: 21. PMID 20604950 DOI: 10.1186/1742-6405-7-21  0.68
2010 Easley R, Carpio L, Dannenberg L, Choi S, Alani D, Van Duyne R, Guendel I, Klase Z, Agbottah E, Kehn-Hall K, Kashanchi F. Transcription through the HIV-1 nucleosomes: effects of the PBAF complex in Tat activated transcription. Virology. 405: 322-33. PMID 20599239 DOI: 10.1016/j.virol.2010.06.009  0.68
2010 Coley W, Van Duyne R, Carpio L, Guendel I, Kehn-Hall K, Chevalier S, Narayanan A, Luu T, Lee N, Klase Z, Kashanchi F. Absence of DICER in monocytes and its regulation by HIV-1. The Journal of Biological Chemistry. 285: 31930-43. PMID 20584909 DOI: 10.1074/jbc.M110.101709  0.68
2010 Morrow MP, Grant A, Mujawar Z, Dubrovsky L, Pushkarsky T, Kiselyeva Y, Jennelle L, Mukhamedova N, Remaley AT, Kashanchi F, Sviridov D, Bukrinsky M. Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1. Molecular Pharmacology. 78: 215-25. PMID 20479131 DOI: 10.1124/mol.110.065029  0.68
2010 Guendel I, Agbottah ET, Kehn-Hall K, Kashanchi F. Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. Aids Research and Therapy. 7: 7. PMID 20334651 DOI: 10.1186/1742-6405-7-7  0.68
2010 Easley R, Carpio L, Guendel I, Klase Z, Choi S, Kehn-Hall K, Brady JN, Kashanchi F. Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes. Journal of Virology. 84: 4755-68. PMID 20164218 DOI: 10.1128/JVI.00851-09  0.68
2010 Easley R, Van Duyne R, Coley W, Guendel I, Dadgar S, Kehn-Hall K, Kashanchi F. Chromatin dynamics associated with HIV-1 Tat-activated transcription. Biochimica Et Biophysica Acta. 1799: 275-85. PMID 19716452 DOI: 10.1016/j.bbagrm.2009.08.008  0.68
2009 Van Duyne R, Kehn-Hall K, Carpio L, Kashanchi F. Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case. Expert Review of Proteomics. 6: 515-26. PMID 19811073 DOI: 10.1586/epr.09.73  0.68
2009 Coley W, Kehn-Hall K, Van Duyne R, Kashanchi F. Novel HIV-1 therapeutics through targeting altered host cell pathways. Expert Opinion On Biological Therapy. 9: 1369-82. PMID 19732026 DOI: 10.1517/14712590903257781  0.68
2009 Kehn-Hall K, Kashanchi F. Novel insights into transcriptional elongation: ubiquitination of HEXIM1 and p-TEFb activity. Cell Cycle (Georgetown, Tex.). 8: 2485. PMID 19684463  0.68
2009 Van Duyne R, Pedati C, Guendel I, Carpio L, Kehn-Hall K, Saifuddin M, Kashanchi F. The utilization of humanized mouse models for the study of human retroviral infections. Retrovirology. 6: 76. PMID 19674458 DOI: 10.1186/1742-4690-6-76  0.68
2009 Guendel I, Carpio L, Easley R, Van Duyne R, Coley W, Agbottah E, Dowd C, Kashanchi F, Kehn-Hall K. 9-Aminoacridine inhibition of HIV-1 Tat dependent transcription. Virology Journal. 6: 114. PMID 19630958 DOI: 10.1186/1743-422X-6-114  0.68
2009 Charles S, Ammosova T, Cardenas J, Foster A, Rotimi J, Jerebtsova M, Ayodeji AA, Niu X, Ray PE, Gordeuk VR, Kashanchi F, Nekhai S. Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration. Journal of Cellular Physiology. 221: 469-79. PMID 19626680 DOI: 10.1002/jcp.21882  0.52
2009 Kashanchi F, Kehn-Hall K. Cyclin dependent kinases as attractive targets to prevent transcription from viral genomes. Current Pharmaceutical Design. 15: 2520-32. PMID 19601848  0.68
2009 Klase Z, Winograd R, Davis J, Carpio L, Hildreth R, Heydarian M, Fu S, McCaffrey T, Meiri E, Ayash-Rashkovsky M, Gilad S, Bentwich Z, Kashanchi F. HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression. Retrovirology. 6: 18. PMID 19220914 DOI: 10.1186/1742-4690-6-18  0.68
2009 Zhou M, Huang K, Jung KJ, Cho WK, Klase Z, Kashanchi F, Pise-Masison CA, Brady JN. Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29. Journal of Virology. 83: 1036-44. PMID 18971272 DOI: 10.1128/JVI.01316-08  0.6
2009 Chen H, Van Duyne R, Zhang N, Kashanchi F, Zeng C. A novel binding pocket of cyclin-dependent kinase 2. Proteins. 74: 122-32. PMID 18615713 DOI: 10.1002/prot.22136  0.68
2008 Burbelo PD, Meoli E, Leahy HP, Graham J, Yao K, Oh U, Janik JE, Mahieux R, Kashanchi F, Iadarola MJ, Jacobson S. Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology. 5: 96. PMID 18937847 DOI: 10.1186/1742-4690-5-96  0.68
2008 Agbottah E, Yeh WI, Berro R, Klase Z, Pedati C, Kehn-Hall K, Wu W, Kashanchi F. Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. Aids Research and Therapy. 5: 12. PMID 18544167 DOI: 10.1186/1742-6405-5-12  0.68
2008 Van Duyne R, Kehn-Hall K, Klase Z, Easley R, Heydarian M, Saifuddin M, Wu W, Kashanchi F. Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication. Expert Review of Proteomics. 5: 507-28. PMID 18532916 DOI: 10.1586/14789450.5.3.507  0.68
2008 Van Duyne R, Easley R, Wu W, Berro R, Pedati C, Klase Z, Kehn-Hall K, Flynn EK, Symer DE, Kashanchi F. Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. Retrovirology. 5: 40. PMID 18498648 DOI: 10.1186/1742-4690-5-40  0.68
2008 Berro R, Pedati C, Kehn-Hall K, Wu W, Klase Z, Even Y, Genevière AM, Ammosova T, Nekhai S, Kashanchi F. CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing. Journal of Virology. 82: 7155-66. PMID 18480452 DOI: 10.1128/JVI.02543-07  0.68
2008 Van Duyne R, Cardenas J, Easley R, Wu W, Kehn-Hall K, Klase Z, Mendez S, Zeng C, Chen H, Saifuddin M, Kashanchi F. Effect of transcription peptide inhibitors on HIV-1 replication. Virology. 376: 308-22. PMID 18455747 DOI: 10.1016/j.virol.2008.02.036  0.68
2008 Chevalier SA, Ko NL, Calattini S, Mallet A, Prévost MC, Kehn K, Brady JN, Kashanchi F, Gessain A, Mahieux R. Construction and characterization of a human T-cell lymphotropic virus type 3 infectious molecular clone. Journal of Virology. 82: 6747-52. PMID 18417569 DOI: 10.1128/JVI.00247-08  0.52
2008 Wu W, Kehn-Hall K, Pedati C, Zweier L, Castro I, Klase Z, Dowd CS, Dubrovsky L, Bukrinsky M, Kashanchi F. Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation. Virology Journal. 5: 41. PMID 18348731 DOI: 10.1186/1743-422X-5-41  0.68
2008 Ku SC, Lee J, Lau J, Gurumurthy M, Ng R, Lwa SH, Lee J, Klase Z, Kashanchi F, Chao SH. XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription. Journal of Virology. 82: 4343-53. PMID 18287238 DOI: 10.1128/JVI.02054-07  0.6
2008 Klase ZA, Van Duyne R, Kashanchi F. Identification of potential drug targets using genomics and proteomics: a systems approach. Advances in Pharmacology (San Diego, Calif.). 56: 327-68. PMID 18086417 DOI: 10.1016/S1054-3589(07)56011-4  0.68
2007 Klase Z, Kale P, Winograd R, Gupta MV, Heydarian M, Berro R, McCaffrey T, Kashanchi F. HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. Bmc Molecular Biology. 8: 63. PMID 17663774 DOI: 10.1186/1471-2199-8-63  0.6
2007 Lee J, Klase Z, Gao X, Caldwell JS, Stinski MF, Kashanchi F, Chao SH. Cellular homeoproteins, SATB1 and CDP, bind to the unique region between the human cytomegalovirus UL127 and major immediate-early genes. Virology. 366: 117-25. PMID 17512569 DOI: 10.1016/j.virol.2007.04.024  0.68
2007 Kehn K, Berro R, Alhaj A, Bottazzi ME, Yeh WI, Klase Z, Van Duyne R, Fu S, Kashanchi F. Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells. Oncogene. 26: 5060-9. PMID 17334399 DOI: 10.1038/sj.onc.1210319  0.68
2007 Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, Agbottah E, Vertes A, Nekhai S, Kashanchi F. Identifying the membrane proteome of HIV-1 latently infected cells. The Journal of Biological Chemistry. 282: 8207-18. PMID 17237230 DOI: 10.1074/jbc.M606324200  0.68
2006 Ammosova T, Berro R, Jerebtsova M, Jackson A, Charles S, Klase Z, Southerland W, Gordeuk VR, Kashanchi F, Nekhai S. Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology. 3: 78. PMID 17083724 DOI: 10.1186/1742-4690-3-78  0.68
2006 Pumfery A, de la Fuente C, Kashanchi F. HTLV-1 Tax: centrosome amplification and cancer. Retrovirology. 3: 50. PMID 16899128 DOI: 10.1186/1742-4690-3-50  0.52
2006 Agbottah E, Deng L, Dannenberg LO, Pumfery A, Kashanchi F. Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription. Retrovirology. 3: 48. PMID 16893449 DOI: 10.1186/1742-4690-3-48  0.68
2006 de la Fuente C, Gupta MV, Klase Z, Strouss K, Cahan P, McCaffery T, Galante A, Soteropoulos P, Pumfery A, Fujii M, Kashanchi F. Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach. Retrovirology. 3: 43. PMID 16822311 DOI: 10.1186/1742-4690-3-43  0.68
2006 Pumfery A, de la Fuente C, Berro R, Nekhai S, Kashanchi F, Chao SH. Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics. Current Pharmaceutical Design. 12: 1949-61. PMID 16787240  0.52
2006 Yao K, Mandel M, Akyani N, Maynard K, Sengamalay N, Fotheringham J, Ghedin E, Kashanchi F, Jacobson S. Differential HHV-6A gene expression in T cells and primary human astrocytes based on multi-virus array analysis. Glia. 53: 789-98. PMID 16541415 DOI: 10.1002/glia.20333  0.68
2006 Berro R, Kehn K, de la Fuente C, Pumfery A, Adair R, Wade J, Colberg-Poley AM, Hiscott J, Kashanchi F. Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32. Journal of Virology. 80: 3189-204. PMID 16537587 DOI: 10.1128/JVI.80.7.3189-3204.2006  0.68
2006 Iordanskiy S, Berro R, Altieri M, Kashanchi F, Bukrinsky M. Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin. Retrovirology. 3: 4. PMID 16409631 DOI: 10.1186/1742-4690-3-4  0.68
2006 Agbottah E, Zhang N, Dadgar S, Pumfery A, Wade JD, Zeng C, Kashanchi F. Inhibition of HIV-1 virus replication using small soluble Tat peptides. Virology. 345: 373-89. PMID 16289656 DOI: 10.1016/j.virol.2005.09.062  0.68
2005 Haffar O, Dubrovsky L, Lowe R, Berro R, Kashanchi F, Godden J, Vanpouille C, Bajorath J, Bukrinsky M. Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein. Journal of Virology. 79: 13028-36. PMID 16189005 DOI: 10.1128/JVI.79.20.13028-13036.2005  0.68
2005 Kashanchi F, Brady JN. Transcriptional and post-transcriptional gene regulation of HTLV-1. Oncogene. 24: 5938-51. PMID 16155601 DOI: 10.1038/sj.onc.1208973  0.36
2005 Ammosova T, Jerebtsova M, Beullens M, Lesage B, Jackson A, Kashanchi F, Southerland W, Gordeuk VR, Bollen M, Nekhai S. Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. The Journal of Biological Chemistry. 280: 36364-71. PMID 16131488 DOI: 10.1074/jbc.M503673200  0.68
2005 Ammosova T, Berro R, Kashanchi F, Nekhai S. RNA interference directed to CDK2 inhibits HIV-1 transcription. Virology. 341: 171-8. PMID 16085226 DOI: 10.1016/j.virol.2005.06.041  0.52
2005 Liang WS, Maddukuri A, Teslovich TM, de la Fuente C, Agbottah E, Dadgar S, Kehn K, Hautaniemi S, Pumfery A, Stephan DA, Kashanchi F. Therapeutic targets for HIV-1 infection in the host proteome. Retrovirology. 2: 20. PMID 15780141 DOI: 10.1186/1742-4690-2-20  0.68
2005 Kehn K, Fuente Cde L, Strouss K, Berro R, Jiang H, Brady J, Mahieux R, Pumfery A, Bottazzi ME, Kashanchi F. The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation. Oncogene. 24: 525-40. PMID 15580311 DOI: 10.1038/sj.onc.1208105  0.52
2005 Agbottah E, de La Fuente C, Nekhai S, Barnett A, Gianella-Borradori A, Pumfery A, Kashanchi F. Antiviral activity of CYC202 in HIV-1-infected cells. The Journal of Biological Chemistry. 280: 3029-42. PMID 15531588 DOI: 10.1074/jbc.M406435200  0.52
2004 Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A. Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription. Journal of Virology. 78: 13522-33. PMID 15564463 DOI: 10.1128/JVI.78.24.13522-13533.2004  0.68
2004 Seelamgari A, Maddukuri A, Berro R, de la Fuente C, Kehn K, Deng L, Dadgar S, Bottazzi ME, Ghedin E, Pumfery A, Kashanchi F. Role of viral regulatory and accessory proteins in HIV-1 replication. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2388-413. PMID 15353294  0.68
2004 Kehn K, Berro R, de la Fuente C, Strouss K, Ghedin E, Dadgar S, Bottazzi ME, Pumfery A, Kashanchi F. Mechanisms of HTLV-1 transformation. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2347-72. PMID 15353292  0.68
2004 Lacoste V, de la Fuente C, Kashanchi F, Pumfery A. Kaposi's sarcoma-associated herpesvirus immediate early gene activity. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2245-72. PMID 15353285  0.68
2004 de la Fuente C, Kashanchi F. The expanding role of Tax in transcription. Retrovirology. 1: 19. PMID 15285790 DOI: 10.1186/1742-4690-1-19  0.52
2004 Kehn K, Deng L, de la Fuente C, Strouss K, Wu K, Maddukuri A, Baylor S, Rufner R, Pumfery A, Bottazzi ME, Kashanchi F. The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells. Retrovirology. 1: 6. PMID 15169570 DOI: 10.1186/1742-4690-1-6  0.52
2004 Ghedin E, Pumfery A, de la Fuente C, Yao K, Miller N, Lacoste V, Quackenbush J, Jacobson S, Kashanchi F. Use of a multi-virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP-chip analysis. Retrovirology. 1: 10. PMID 15169557 DOI: 10.1186/1742-4690-1-10  0.68
2004 Wu K, Bottazzi ME, de la Fuente C, Deng L, Gitlin SD, Maddukuri A, Dadgar S, Li H, Vertes A, Pumfery A, Kashanchi F. Protein profile of tax-associated complexes. The Journal of Biological Chemistry. 279: 495-508. PMID 14530271 DOI: 10.1074/jbc.M310069200  0.68
2003 Pumfery A, Deng L, Maddukuri A, de la Fuente C, Li H, Wade JD, Lambert P, Kumar A, Kashanchi F. Chromatin remodeling and modification during HIV-1 Tat-activated transcription. Current Hiv Research. 1: 343-62. PMID 15046258  0.52
2003 de la Fuente C, Maddukuri A, Kehn K, Baylor SY, Deng L, Pumfery A, Kashanchi F. Pharmacological cyclin-dependent kinase inhibitors as HIV-1 antiviral therapeutics. Current Hiv Research. 1: 131-52. PMID 15043199  0.52
2003 Zhou M, Deng L, Kashanchi F, Brady JN, Shatkin AJ, Kumar A. The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA. Proceedings of the National Academy of Sciences of the United States of America. 100: 12666-71. PMID 14569024 DOI: 10.1073/pnas.1835726100  0.68
2003 de la Fuente C, Wang L, Wang D, Deng L, Wu K, Li H, Stein LD, Denny T, Coffman F, Kehn K, Baylor S, Maddukuri A, Pumfery A, Kashanchi F. Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells. Molecular and Cellular Biochemistry. 245: 99-113. PMID 12708749  0.52
2002 Wang L, Deng L, Wu K, de la Fuente C, Wang D, Kehn K, Maddukuri A, Baylor S, Santiago F, Agbottah E, Trigon S, Morange M, Mahieux R, Kashanchi F. Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors. Molecular and Cellular Biochemistry. 237: 137-53. PMID 12236581  0.52
2002 Deng L, Ammosova T, Pumfery A, Kashanchi F, Nekhai S. HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter. The Journal of Biological Chemistry. 277: 33922-9. PMID 12114499 DOI: 10.1074/jbc.M111349200  0.52
2002 de la Fuente C, Santiago F, Deng L, Eadie C, Zilberman I, Kehn K, Maddukuri A, Baylor S, Wu K, Lee CG, Pumfery A, Kashanchi F. Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals. Bmc Biochemistry. 3: 14. PMID 12069692  0.52
2002 Furia B, Deng L, Wu K, Baylor S, Kehn K, Li H, Donnelly R, Coleman T, Kashanchi F. Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins. The Journal of Biological Chemistry. 277: 4973-80. PMID 11739381 DOI: 10.1074/jbc.M107848200  0.52
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