Deepak Kaushal - Publications

Affiliations: 
Biomedical Sciences Tulane University, New Orleans, LA, United States 
Area:
Microbiology Biology, Pathology, Immunology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Esaulova E, Das S, Singh DK, Choreño-Parra JA, Swain A, Arthur L, Rangel-Moreno J, Ahmed M, Singh B, Gupta A, Fernández-López LA, de la Luz Garcia-Hernandez M, Bucsan A, Moodley C, Mehra S, ... ... Kaushal D, et al. The immune landscape in tuberculosis reveals populations linked to disease and latency. Cell Host & Microbe. PMID 33340449 DOI: 10.1016/j.chom.2020.11.013  0.4
2020 Coskun FS, Srivastava S, Raj P, Dozmorov I, Belkaya S, Mehra S, Golden NA, Bucsan AN, Chapagain ML, Wakeland EK, Kaushal D, Gumbo T, van Oers NSC. sncRNA-1 Is a Small Noncoding RNA Produced by in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis. Frontiers in Microbiology. 11: 1631. PMID 32849337 DOI: 10.3389/fmicb.2020.01631  0.52
2020 Ganatra SR, Bucsan AN, Alvarez X, Kumar S, Chatterjee A, Quezada M, Fish AI, Singh DK, Singh B, Sharan R, Lee TH, Shanmugasundaram U, Velu V, Khader SA, Mehra S, ... ... Kaushal D, et al. Anti-retroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV co-infection model. The Journal of Clinical Investigation. PMID 32544085 DOI: 10.1172/JCI136502  0.4
2020 Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Chronic Immune Activation in TB/HIV Co-infection: (Trends in Microbiology 28, XXX-XXX; 2020). Trends in Microbiology. PMID 32482557 DOI: 10.1016/j.tim.2020.05.006  0.4
2020 Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Chronic Immune Activation in TB/HIV Co-infection. Trends in Microbiology. PMID 32417227 DOI: 10.1016/j.tim.2020.03.015  0.4
2020 Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, ... ... Kaushal D, et al. S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis. The Journal of Clinical Investigation. PMID 32134742 DOI: 10.1172/JCI130546  0.4
2020 Ahmed M, Thirunavukkarasu S, Rosa BA, Thomas KA, Das S, Rangel-Moreno J, Lu L, Mehra S, Mbandi SK, Thackray LB, Diamond MS, Murphy KM, Means T, Martin J, Kaushal D, et al. Immune correlates of tuberculosis disease and risk translate across species. Science Translational Medicine. 12. PMID 31996462 DOI: 10.1126/scitranslmed.aay0233  0.4
2019 Gautam US, Mehra S, Kumari P, Alvarez X, Niu T, Tyagi JS, Kaushal D. Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner. Communications Biology. 2: 349. PMID 31925209 DOI: 10.1038/s42003-019-0594-0  0.4
2019 Alberto Choreño-Parra J, Bobba S, Rangel-Moreno J, Ahmed M, Mehra S, Rosa B, Martin J, Mitreva M, Kaushal D, Zúñiga J, Khader SA. Mycobacterium tuberculosis HN878 infection induces human-like B cell follicles in mice. The Journal of Infectious Diseases. PMID 31832640 DOI: 10.1093/infdis/jiz663  0.4
2019 Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Isoniazid and Rifapentine Treatment Eradicates Persistent in Macaques. American Journal of Respiratory and Critical Care Medicine. PMID 31647877 DOI: 10.1164/rccm.201903-0646OC  0.4
2019 Gautam US, Mehra S, Kumari P, Alvarez X, Niu T, Tyagi JS, Kaushal D. sensor kinase DosS modulates the autophagosome in a DosR-independent manner. Communications Biology. 2: 349. PMID 31552302 DOI: 10.1038/s42003-019-0594-0  0.4
2019 Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection. The Journal of Clinical Investigation. PMID 31479428 DOI: 10.1172/JCI125810  0.4
2019 Bucsan AN, Mehra S, Khader SA, Kaushal D. The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease. Pathogens and Disease. PMID 31381766 DOI: 10.1093/femspd/ftz037  0.4
2018 Vashistha H, Marrero L, Reiss K, Cohen A, Malhotra A, Javed T, Bradley AE, Abbruscato F, Giusti S, Jimenez A, Mehra S, Kaushal D, Giorgio M, Pelicci PG, Kakoki M, et al. Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent. American Journal of Physiology. Renal Physiology. PMID 30207172 DOI: 10.1152/ajprenal.00608.2017  0.4
2018 Kuroda MJ, Sugimoto C, Cai Y, Merino KM, Mehra S, Araínga M, Roy CJ, Midkiff CC, Alvarez X, Didier ES, Kaushal D. High Turnover of Tissue Macrophages Contributes to Tuberculosis Reactivation in Simian Immunodeficiency Virus-Infected Rhesus Macaques. The Journal of Infectious Diseases. PMID 29432596 DOI: 10.1093/infdis/jix625  0.4
2017 Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, ... ... Kaushal D, et al. In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255022 DOI: 10.1073/pnas.1711373114  0.64
2017 Foreman TW, Veatch AV, LoBato DN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Lackner AA, Kousoulas KG, Khader SA, Kaushal D, Mehra S. Non-pathological infection of macaques by an attenuated mycobacterial vaccine is not reactivated in the setting of HIV coinfection. The American Journal of Pathology. PMID 28935575 DOI: 10.1016/j.ajpath.2017.08.014  0.64
2017 Veatch AV, Kaushal D. Opening Pandora's Box: Mechanisms of Mycobacterium tuberculosis Resuscitation. Trends in Microbiology. PMID 28911979 DOI: 10.1016/j.tim.2017.08.001  0.64
2017 Phillips BL, Gautam US, Bucsan AN, Foreman TW, Golden NA, Niu T, Kaushal D, Mehra S. LAG-3 potentiates the survival of Mycobacterium tuberculosis in host phagocytes by modulating mitochondrial signaling in an in-vitro granuloma model. Plos One. 12: e0180413. PMID 28880895 DOI: 10.1371/journal.pone.0180413  0.52
2017 Cheng CY, Gutierrez NM, Marzuki MB, Lu X, Foreman TW, Paleja B, Lee B, Balachander A, Chen J, Tsenova L, Kurepina N, Teng KWW, West K, Mehra S, Zolezzi F, ... ... Kaushal D, et al. Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis. Science Immunology. 2. PMID 28707004 DOI: 10.1126/sciimmunol.aaj1789  0.4
2017 Foreman TW, Mehra S, Lackner AA, Kaushal D. Translational Research in the Nonhuman Primate Model of Tuberculosis. Ilar Journal. 1-9. PMID 28575319 DOI: 10.1093/ilar/ilx015  0.4
2017 Hudock TA, Foreman TW, Bandyopadhyay N, Gautam US, Veatch A, LoBato DN, Gentry KM, Golden NA, Cavigli A, Mueller M, Hwang SA, Hunter RL, Alvarez X, Lackner AA, Bader JS, ... ... Kaushal D, et al. Hypoxia Sensing and Persistence Genes are Expressed During the Intra-granulomatous Survival of M. tuberculosis. American Journal of Respiratory Cell and Molecular Biology. PMID 28135421 DOI: 10.1165/rcmb.2016-0239OC  0.52
2016 Veatch AV, Niu T, Caskey J, McGillivray A, Gautam US, Subramanian R, Kousoulas KG, Mehra S, Kaushal D. Sequencing-relative to hybridization-based transcriptomics approaches better define Mycobacterium tuberculosis stress-response regulons. Tuberculosis (Edinburgh, Scotland). PMID 27729257 DOI: 10.1016/j.tube.2016.09.020  0.64
2016 Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, ... ... Kaushal D, et al. CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601645 DOI: 10.1073/pnas.1611987113  0.52
2015 Mothé BR, Lindestam Arlehamn CS, Dow C, Dillon MB, Wiseman RW, Bohn P, Karl J, Golden NA, Gilpin T, Foreman TW, Rodgers MA, Mehra S, Scriba TJ, Flynn JL, Kaushal D, et al. The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans. Tuberculosis (Edinburgh, Scotland). PMID 26526557 DOI: 10.1016/j.tube.2015.07.005  0.52
2015 Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, et al. Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nature Communications. 6: 8533. PMID 26460802 DOI: 10.1038/ncomms9533  0.52
2015 Gautam US, Mehra S, Kaushal D. In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice. Plos One. 10: e0135208. PMID 26270051 DOI: 10.1371/journal.pone.0135208  0.4
2015 Levine DM, Dutta NK, Eckels J, Scanga C, Stein C, Mehra S, Kaushal D, Karakousis PC, Salamon H. A tuberculosis ontology for host systems biology. Tuberculosis (Edinburgh, Scotland). 95: 570-4. PMID 26190839 DOI: 10.1016/j.tube.2015.05.012  0.4
2015 Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, Golden NA, Gautam US, Johnson AM, Alvarez X, Russell-Lodrigue KE, Doyle LA, Roy CJ, Niu T, Blanchard JL, ... ... Kaushal D, et al. The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence. American Journal of Respiratory and Critical Care Medicine. 191: 1185-96. PMID 25730547 DOI: 10.1164/rccm.201408-1502OC  0.52
2015 Phillips BL, Mehra S, Ahsan MH, Selman M, Khader SA, Kaushal D. LAG3 expression in active Mycobacterium tuberculosis infections. The American Journal of Pathology. 185: 820-33. PMID 25549835 DOI: 10.1016/j.ajpath.2014.11.003  0.4
2015 McGillivray A, Golden NA, Kaushal D. The Mycobacterium tuberculosis Clp gene regulator is required for in vitro reactivation from hypoxia-induced dormancy. The Journal of Biological Chemistry. 290: 2351-67. PMID 25422323 DOI: 10.1074/jbc.M114.615534  0.52
2015 Gautam US, McGillivray A, Mehra S, Didier PJ, Midkiff CC, Kissee RS, Golden NA, Alvarez X, Niu T, Rengarajan J, Sherman DR, Kaushal D. DosS Is Required for the Complete Virulence of Mycobacterium tuberculosis in Mice with Classical Granulomatous Lesions. American Journal of Respiratory Cell and Molecular Biology. 52: 708-16. PMID 25322074 DOI: 10.1165/rcmb.2014-0230OC  0.52
2014 Dutta NK, McLachlan J, Mehra S, Kaushal D. Humoral and lung immune responses to Mycobacterium tuberculosis infection in a primate model of protection (.) Trials in Vaccinology. 3: 47-51. PMID 25197327 DOI: 10.1016/j.trivac.2014.02.001  0.4
2014 Luo Q, Mehra S, Golden NA, Kaushal D, Lacey MR. Identification of biomarkers for tuberculosis susceptibility via integrated analysis of gene expression and longitudinal clinical data. Frontiers in Genetics. 5: 240. PMID 25104956 DOI: 10.3389/fgene.2014.00240  0.52
2014 Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, et al. Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge. Journal of Immunology (Baltimore, Md. : 1950). 193: 1799-811. PMID 25024382 DOI: 10.4049/jimmunol.1400676  0.4
2014 Gautam US, Mehra S, Ahsan MH, Alvarez X, Niu T, Kaushal D. Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages. Plos One. 9: e95220. PMID 24743303 DOI: 10.1371/journal.pone.0095220  0.4
2014 McGillivray A, Golden NA, Gautam US, Mehra S, Kaushal D. The Mycobacterium tuberculosis Rv2745c plays an important role in responding to redox stress. Plos One. 9: e93604. PMID 24705585 DOI: 10.1371/journal.pone.0093604  0.52
2013 Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, ... ... Kaushal D, et al. S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis. American Journal of Respiratory and Critical Care Medicine. 188: 1137-46. PMID 24047412 DOI: 10.1164/rccm.201304-0803OC  0.4
2013 Martinez AN, Mehra S, Kaushal D. Role of interleukin 6 in innate immunity to Mycobacterium tuberculosis infection. The Journal of Infectious Diseases. 207: 1253-61. PMID 23359591 DOI: 10.1093/infdis/jit037  0.4
2013 Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA. CXCR5⁺ T helper cells mediate protective immunity against tuberculosis. The Journal of Clinical Investigation. 123: 712-26. PMID 23281399 DOI: 10.1172/JCI65728  0.4
2013 Mehra S, Alvarez X, Didier PJ, Doyle LA, Blanchard JL, Lackner AA, Kaushal D. Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis. The Journal of Infectious Diseases. 207: 1115-27. PMID 23255564 DOI: 10.1093/infdis/jis778  0.4
2013 Renner NA, Sansing HA, Inglis FM, Mehra S, Kaushal D, Lackner AA, Maclean AG. Transient acidification and subsequent proinflammatory cytokine stimulation of astrocytes induce distinct activation phenotypes. Journal of Cellular Physiology. 228: 1284-94. PMID 23154943 DOI: 10.1002/jcp.24283  0.4
2012 Kaushal D, Mehra S. Faithful Experimental Models of Human Mycobacterium Tuberculosis Infection. Mycobacterial Diseases : Tuberculosis & Leprosy. 2. PMID 24490123 DOI: 10.4172/2161-1068.1000e108  0.4
2012 Bao L, Hazari S, Mehra S, Kaushal D, Moroz K, Dash S. Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298. The American Journal of Pathology. 180: 2490-503. PMID 22521303 DOI: 10.1016/j.ajpath.2012.02.024  0.4
2012 Kaushal D, Mehra S, Didier PJ, Lackner AA. The non-human primate model of tuberculosis. Journal of Medical Primatology. 41: 191-201. PMID 22429048 DOI: 10.1111/j.1600-0684.2012.00536.x  0.4
2012 Mehra S, Golden NA, Stuckey K, Didier PJ, Doyle LA, Russell-Lodrigue KE, Sugimoto C, Hasegawa A, Sivasubramani SK, Roy CJ, Alvarez X, Kuroda MJ, Blanchard JL, Lackner AA, Kaushal D. The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs. The Journal of Infectious Diseases. 205: 1203-13. PMID 22402035 DOI: 10.1093/infdis/jis102  0.52
2012 Dutta NK, Mehra S, Martinez AN, Alvarez X, Renner NA, Morici LA, Pahar B, Maclean AG, Lackner AA, Kaushal D. The stress-response factor SigH modulates the interaction between Mycobacterium tuberculosis and host phagocytes. Plos One. 7: e28958. PMID 22235255 DOI: 10.1371/journal.pone.0028958  0.4
2012 Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D. Aerosolized gentamicin reduces the burden of tuberculosis in a murine model. Antimicrobial Agents and Chemotherapy. 56: 883-6. PMID 22143521 DOI: 10.1128/AAC.05633-11  0.52
2012 Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D. Aerosolized gentamicin reduces the burden of tuberculosis in a murine model (Antimicrobial Agents and Chemotherapy (2012) 56, 2 (883-886)) Antimicrobial Agents and Chemotherapy. 56: 1672. DOI: 10.1128/AAC.00190-12  0.52
2011 Mehra S, Golden NA, Dutta NK, Midkiff CC, Alvarez X, Doyle LA, Asher M, Russell-Lodrigue K, Monjure C, Roy CJ, Blanchard JL, Didier PJ, Veazey RS, Lackner AA, Kaushal D. Reactivation of latent tuberculosis in rhesus macaques by coinfection with simian immunodeficiency virus. Journal of Medical Primatology. 40: 233-43. PMID 21781131 DOI: 10.1111/j.1600-0684.2011.00485.x  0.52
2011 Sestak K, Conroy L, Aye PP, Mehra S, Doxiadis GG, Kaushal D. Improved xenobiotic metabolism and reduced susceptibility to cancer in gluten-sensitive macaques upon introduction of a gluten-free diet. Plos One. 6: e18648. PMID 21533263 DOI: 10.1371/journal.pone.0018648  0.4
2010 Mehra S, Pahar B, Dutta NK, Conerly CN, Philippi-Falkenstein K, Alvarez X, Kaushal D. Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas. Plos One. 5: e12266. PMID 20824205 DOI: 10.1371/journal.pone.0012266  0.4
2010 Mehra S, Dutta NK, Mollenkopf HJ, Kaushal D. Mycobacterium tuberculosis MT2816 encodes a key stress-response regulator. The Journal of Infectious Diseases. 202: 943-53. PMID 20701538 DOI: 10.1086/654820  0.4
2010 Dutta NK, Mehra S, Didier PJ, Roy CJ, Doyle LA, Alvarez X, Ratterree M, Be NA, Lamichhane G, Jain SK, Lacey MR, Lackner AA, Kaushal D. Genetic requirements for the survival of tubercle bacilli in primates. The Journal of Infectious Diseases. 201: 1743-52. PMID 20394526 DOI: 10.1086/652497  0.4
2010 Dutta NK, Mehra S, Kaushal D. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. Plos One. 5: e10069. PMID 20386700 DOI: 10.1371/journal.pone.0010069  0.4
2009 Mehra S, Kaushal D. Functional genomics reveals extended roles of the Mycobacterium tuberculosis stress response factor sigmaH. Journal of Bacteriology. 191: 3965-80. PMID 19376862 DOI: 10.1128/JB.00064-09  0.4
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